Claim: Tumor-free flounder: Study underscores Boston Harbor rebirth.
Verdict: SUPPORTS

Retrieved passages:
title: Sarah Fraser Robbins
text: the swim was sponsored by the Massachusetts Audubon Society. In that year its name was changed to “Celebrate the Clean Harbor,” since the conditions had immensely improved. The Weld family sponsored a harbor cleanup research and monitoring program under the auspices of the Massachusetts Society to ensure that the federal funding necessary that the program was spent wisely. Currently, the race is sponsored by the New England Marathon Swimming Association. Robbins swam it for many years, and her daughter Sarah has succeeded her. In 1970, the University of Massachusetts Amherst bought the defunct Consolidated Lobster Company buildings at Hodgkins Cove

title: Menemsha Pond
text: of Lobsterville and Squibnocket, both of whom would never recover. The new dredging of Menemsha harbor, with its added depth and dock space, made it ideal for the newly innovated motor-powered fishing and leisure boats. The pond is dually administered by the towns of Aquinnah and Chilmark. Each town has their own harbormaster. Menemsha Pond supports commercial oyster farming. The towns also seed bay scallops, quahogs, and oysters in the pond. In addition, the Wampanoag Tribe of Gay Head runs a hatchery on the southwest side of the pond. In the past, the hatchery conducted flounder spawning programs. Currently, there

title: John Todd (Canadian biologist)
text: first trials, I knew that it was possible to do good things in bad places; in short, to heal the planet." By 1990 a full-scale project was being planned for Harwich's Flax Pond, a 15 acre site. The pond suffered from significant contamination due to leachates from a nearby landfill and septage lagoons. Oxygen levels in the water were low and coliform bacteria counts were high. Sediment deposits included high levels of ammonia, up to 300 times the usual levels of phosphorus, and 80 times the usual concentration of iron. A floating construction called a Pond Restorer was completed in

title: Massachusetts Water Resources Authority
text: bonds that financed major capital improvement projects. Since its creation in 1985, MWRA has completed $6.8 billion worth of upgrades to its water and sewer systems. These projects have all but reversed the effects of neglect and underfunding of the previous decades. With the sewer treatment facilities on Deer Island complete, the clean-up of Boston Harbor has gained national acclaim as one of the greatest environmental success stories of our time. On the drinking water side, massive upgrades to water infrastructure, including a state-of-the-art ozone disinfection plant and covered storage tanks throughout the district guarantee some of the best drinking

title: Boston Harbor
text: polluted that The Standells released a song in 1965 called "Dirty Water" which referred to the sorry state of the Charles River. Neal Stephenson, who attended Boston University from 1977 to 1981, based his second novel, "Zodiac", around pollution of the harbor. Since the writing of the song, the water quality in both the Harbor and the Charles River has significantly improved, and the projects have dramatically transformed Boston Harbor from one of the filthiest in the nation to one of the cleanest. Today Boston Harbor is safe for fishing and for swimming nearly every day, though there are still

title: Provincetown Harbor
text: resulted in the demise of native wildlife populations, occasionally in the form of fish kills. In 2004, tidal flow was successfully restored by the National Park Service, working together with other local, state, and federal agencies. In the following year, for the first time since Abraham Lincoln was president, legal-size clams were found in East Harbor. In 2008, the USGS officially renamed Pilgrim Lake, restoring the original appellation of East Harbor. The Portland gale of 1898 destroyed several wharves and fishing vessels within the harbor. In 2002, Provincetown Harbor Beach was selected by the US Environmental Protection Agency as one

title: Cysview
text: The results of the trial demonstrate that Hexvix identified lesions, including residual tumours, that were not detected with white light alone in 49% of the patients. It also demonstrated that the improved detection of lesions resulted in a significant reduction in tumour recurrence within 12 months. May 12, 2011 - Results announced from a clinical study which included retrospective follow up from 526 patients in a prospective randomized Phase III trial in 28 centers in EU and North America. After the follow-up period up to 5.5 years, the number of patients who have experienced recurrence of their bladder cancer is

title: William B. Golden
text: directly into the harbor, greatly improving the beach ecosystem and economy in the area. Accordingly, in January 1985, State Senator Golden went on to form the nonprofit environmental group Save the Harbor/Save the Bay with Judge Paul Garrity and Boston Globe columnist Ian Menzies, to lobby for the restoration and preservation of Boston Harbor and Massachusetts Bay. The Environmental Protection Agency now calls the Boston Harbor a "great American jewel." Golden serves as the Executive Director of the National Institute for Coastal and Harbor Infrastructure (NICHI). The website for the non-profit organization states that "NICHI is committed to building a

title: Brentuximab vedotin
text: by targeted cells. The vesicle containing the drug is fused with lysosomes and lysosomal cysteine proteases, particularly cathepsin B, start to break down valine-citrulline linker and MMAE is no longer bound to the antibody and is released directly into the tumor environment. In a 2010 clinical trial, 34% of patients with refractory Hodgkin Lymphoma achieved complete remission and another 40% had partial remission. Tumor reductions were achieved in 94% of patients. In ALCL, 87% of patients had tumors shrink at least 50% and 97% of patients had some tumor shrinkage. Reports in 2013 showed interim results from a Phase II,

title: Moon Island (Massachusetts)
text: Quincy's beaches, the City of Quincy filed a lawsuit in state court against the MDC. As a result, the Massachusetts Water Resources Authority (MWRA) was created to manage the cleanup of Boston Harbor. Judge Troy made a judicial decision that prohibited the attachment of any new buildings or homes to the existing sewer system until a plan was established to solve the sewerage overflow problem in Boston Harbor. In 1985, the MWRA assumed control of all of the MDCs water and sewer systems. Because these systems were below federal standards, a federal court order mandated the construction of a new

title: Boston Harbor
text: the Nut Island sewage treatment plant in Quincy and the companion Deer Island plant adjacent to Winthrop had far-reaching environmental and political effects. Fecal coliform bacteria levels forced frequent swimming prohibitions along the harbor beaches and the Charles River for many years. The city of Quincy sued the Metropolitan District Commission (MDC) and the separate Boston Water and Sewer Commission in 1982, charging that unchecked systemic pollution of the city’s waterfront contributed to the problem. That suit was followed by one by the Conservation Law Foundation and finally by the United States government, resulting in the landmark court-ordered cleanup of

title: Brigham and Women's Hospital
text: of EGFR mutations and their role in directing management with targeted tyrosine kinase inhibitors. Since 2003 this has reshaped the approach at the molecular diagnostic testing center at the Brigham and Women's Hospital/Dana-Farber Cancer Institute. In 2017, the hospital will host the first human clinical trials to reverse the ageing process using NAD+. The trials will be headed by biologist David Sinclair. Brigham and Women's represents the 1980 merger of three Harvard-affiliated Boston hospitals: In 1954, the Peter Bent Brigham hospital became the location for the first ever successful kidney transplant, performed by Joseph Murray, on Richard Herrick. After a

title: Shawmut Peninsula
text: move the site of Winthrop's colonial settlement to the peninsula from what is now Charlestown. The Charlestown peninsula lacked a source of fresh water, while the Shawmut peninsula had an "excellent spring" on the north side of what is now Beacon Hill. Reclamation projects began in 1820 and continued intermittently until 1900 and created the Boston neighborhoods of the South End, Back Bay, and Fenway-Kenmore. The Back Bay Fens, a freshwater urban wild in the latter area, is a remnant of the salt marshes that once surrounded Shawmut Peninsula. Although this project eliminated the wetland ecosystem that existed there at

title: Moon Island (Massachusetts)
text: all clams taken in the area required purification processing before sale or consumption. Pollution on the Boston and Quincy beaches worsened. In 1939, a legislature committee found that Quincy Bay and Hingham Harbor were "revolting" and "in violation of all public health requirements." Both Boston and Quincy beaches have been closed since 1890. More than of raw sewage were being dumped into Boston Harbor daily. The following year, Massachusetts State planners recommended the construction of sewage treatment plants at Moon Island, Deer Island, and Nut Island in Quincy. On August 4, 1951, then Secretary of Labor, Maurice J. Tobin, dedicated

title: Neighborhoods of Norwich, Connecticut
text: to a pleasure craft marina on the south end and a decaying industrial zone with a sewage treatment plant on the north end. Several important buildings in downtown have been renovated, specifically the Wauregan Hotel, Chelsea Landing and Otis Library. Although not completely salvaged, Hollyhock Island was freed of the abandoned Duffy Mill complex. In 2012 a $22 million Intermodal Transportation Center was dedicated on Hollyhock Island. As of March 2015, the building remains mostly vacant except for serving as a turnaround for the region's Southeast Area Transit Authority (SEAT) buses. The harbor area and Howard T. Brown Park are

title: J. William Harbour
text: was accepted to the Howard Hughes Medical Institute–National Institutes of Health (HHMI–NIH) Research Scholars Program in Bethesda, MD, where he carried out research in the National Cancer Institute laboratory of Dr. John Minna. This research resulted in a breakthrough discovery published in the journal "Science" in 1988, with Harbour as first author. Previously it had been thought that mutations in the retinoblastoma gene, the first tumor suppressor gene to be discovered, would be limited to the rare eye cancer retinoblastoma. However, Harbour and co-authors showed that the gene was commonly mutated in a common form of lung cancer. This discovery

title: Ipilimumab
text: further trials. On June 19, 2009, the Mayo Clinic reported two prostate cancer patients involved in a phase II study using MDX-010 therapy who had been told initially that their condition was inoperable but had their tumors shrunk by the drug such that operation was possible and are now cancer-free as a result. This press report however was criticized as premature and somewhat inaccurate. The clinical trials were still at an early stage and were run alongside other treatments – which could have been the real explanation for the tumor shrinkage. It was too early to say whether ipilimumab made

title: Wollaston Beach
text: from the Nut Island plant at the end of Houghs Neck. The outfall pipe was known as the 'bubbler'. Officials permanently closed the beach to shell fishing and even swimmers. In 1982, the city of Quincy successfully sued the Commonwealth of Massachusetts for violating the Clean Water Act. The city of Quincy has been a leader in environmental cleanup around Massachusetts Bay and, in 1988, a program was established to help clean up Massachusetts Bay beaches, and testing along Wollaston Beach has demonstrated since 2006 that it is once again safe for swimming and recreation. In 1990, Massachusetts Bay was

title: Boston Harbor Islands National Recreation Area
text: involved using the old tanks and granite canals on Moon Island. In 2008, Peddocks Island was used for filming scenes in Martin Scorsese's "Shutter Island". The Boston Harbor Islands National Recreation Area is made up of a series of discrete islands and other places on and around Boston Harbor. These include: Two islands (Castle Island and Spinnaker Island) in Boston Harbor are not part of the National Recreation Area, and other former islands ("e.g." Apple Island, Governors Island and Noddle's Island) were obliterated by the formation of East Boston and the expansion of Logan International Airport before the area was

title: East Harbor
text: East Harbor East Harbor is the name of a tidal estuary in Truro, Massachusetts that was formerly a harbor until it was cut off from Cape Cod Bay. It is now within Cape Cod National Seashore. After an oxygen depletion and fish kill in 2001, the town and the National Park Service began to explore options to restore the estuary. Over time, the blockage of tides has caused numerous ecological problems. The lack of tidal flushing had deprived the system of salty, nutrient-poor, oxygen-rich Cape Cod Bay water and it became a stagnant freshwater pond. These conditions resulted in midge