Claim: A few drops of Visine brand eye drops taken internally will induce uncontrollable diarrhea.
Verdict: REFUTES

Retrieved passages:
title: Visine
text: but debilitating bouts of explosive diarrhea, akin to that of a laxative. This will not produce explosive diarrhea, but oral administration of Visine can induce dangerous side effects related to Visine's ingredient tetrahydrozoline hydrochloride such as: Anyone ingesting Visine should get medical attention or contact a poison control center immediately. Visine is formulated in several varieties: VISINE A.C. - Astringent/Redness Reliever Eye Drops (Tetrahydrozoline HCl 0.05%, Zinc sulfate 0.25%) VISINE FOR CONTACTS - For Silicone Hydrogel and Hydrophilic lenses VISINE L.R. (Oxymetazoline HCI 0.025%) VISINE TEARS (Glycerin 0.2%, Hypromellose 0.2%, Polyethylene glycol 400 1% - Used AS NEEDED) VISINE-A (Formerly

title: Visine
text: Visine Visine is a brand of eye drops produced by Johnson & Johnson. Johnson & Johnson acquired Visine, along with Pfizer's entire consumer healthcare portfolio, in December 2006. In some countries it is called Vispring. The active ingredients in the original Visine formulation are potassium chloride and tetrahydrozoline hydrochloride which is a vasoconstrictor, and therefore constricts the eye's superficial blood vessels. Visine is administered topically with 1 to 2 drops applied to the affected eye(s) up to 4 times daily . A common urban legend is that a few drops of Visine in an unsuspecting victim's drink will cause harmless

title: Visine
text: putting Visine eyedrops in drinking water bottles, threatening severe or fatal injury to drinkers. The urban legend about Visine's explosive diarrhea-inducing capacity is also perpetuated in the movie version of "I Hope They Serve Beer in Hell". In the movie, the main character Tucker Max (played by Matt Czuchry) is making fun of two women at the bar, in which one of them squirts Visine into his beer bottle. This leads to Tucker and an allegedly married woman he leaves the bar with to both have extreme explosive diarrhea. Visine Visine is a brand of eye drops produced by Johnson

title: Tetryzoline
text: putting a few drops of Visine in an unsuspecting person's beverage. However, the actual results of the prank may be worse, varying from severe nausea and vomiting to seizures or a coma. Diarrhea is not a side effect. In late August 2018, a South Carolina woman, was charged with murdering her husband by putting eye drops containing tetryzoline his drinking water. An autopsy found high concentrations of tetryzoline in his body. Tetryzoline has been used as a date rape drug in a number of cases due to its ability to cause dizziness and unconsciousness. Tetryzoline was used as a plot

title: Motofen
text: Food and Drug Administration (FDA) for diarrhea, it has also been successfully used by physicians for irritable bowel syndrome (IBS), and hyperhidrosis (chronic, severe sweating). Side effects include drowsiness, nausea, vomiting, burning eyes, blurred vision, dry eyes, dizziness, dry mouth, epigastric distress, and constipation (a paradoxical side effect). Side effects attributed to the atropine content (especially when taken in excess doses, or in children), include: flushing, dryness in many areas, urinary retention, insomnia, headache, anxiety, hyperthermia, and tachycardia. It is these side effects that make it undesirable for most patients to take higher amounts of the medicine. The recommended initial

title: Euphorbia tithymaloides
text: reduced visual actuity occur. Ingesting even a few seeds can cause violent and persistent vomiting and extreme diarrhea. If latex or root juice gets on the skin, the victim should immediately wash with soap and warm water. If latex or juice gets in the eye, continuous rinsing with fresh water should be the first course of action. Topical steroids are indicated for skin or eye contact. Intravenous fluids are often administered to counteract the fluid loss due to vomiting and diarrhea. The root is known to be a powerful emetic. A proteolytic enzyme known as pedilanthain can be extracted from

title: Eye drop
text: aerosolized dust particles. Antibiotic eye drops are prescribed when conjunctivitis is caused by bacteria but not when it is caused by a virus. In the case of allergic conjunctivitis, artificial tears can help dilute irritating allergens present in the tear film. These make the eye's pupil widen to maximum, to let an optimetrist have the best view inside the eyeball behind the iris. Afterwards in sunny weather they can cause dazzling and photophobia until the effect of the mydriatic has worn off. In Russia, Tropicamide, a mydriatic eye drop, is used to some degree as an inexpensive recreational drug. Like

title: Emedastine
text: Emedastine Emedastine (trade name Emadine) is a second generation antihistamine used in eye drops to alleviate the symptoms of allergic conjunctivitis. It acts as a H receptor antagonist. It works by blocking the action of histamine that causes allergic symptoms. It is used in form of the difumarate. The emedastine difumarate is a white, crystalline, water-soluble fine powder. Emedastine eye drops is usually applied twice a day to the affected eye. When the patients with allergic conjunctivitis were treated with 0.05% emedastine difumarate ophthalmic solution for six weeks, the signs and symptoms such as redness, itching and swelling of the

title: Eye drop
text: other anticholinergics, when taken recreationally, tropicamide acts as a deliriant. According to one reporter, when injected intravenously, as is most often the case, the drug often "brings on suicidal feelings." Syringe designed saline drops (e.g. Wallace Cameron Ultra Saline Minipod) are distributed in modern needle-exchange programmes as they can be used efficiently either by injection or ophthalmic (if the drug is potent in small doses) route of administer which is compared to intravenous use; By demonstration, the elimination of latanoprost acid from plasma is rapid (half-life 17 minutes) after either ophthalmic or intravenous administration. Steroid and antibiotic eye drops may

title: Eye drop
text: shortness of breath, and in rare occasions, reduced libido and depression. Alpha agonists can cause burning or stinging, fatigue, headache, drowsiness, dry mouth and nose, and also they have a higher likelihood of allergic reaction. Carbonic anhydrase inhibitors may cause stinging, burning, and eye discomfort. Lubricant eye drops may cause some side effects and one should consult a doctor if pain in the eye or changes in vision occur. Furthermore, when redness occurs but lasts more than 3 days, one should immediately consult a doctor. Eye droppers are also used in watercolor painting. Eye drop Eye drops are saline-containing drops

title: Brimonidine/timolol
text: patients who need more than one medication to lower IOP, the fixed combination product offers the advantages of reducing the number of drops and medication bottles, improving patient compliance, and decreasing ocular exposure to preservatives in ophthalmic solutions. The most common adverse effects affecting 5 to 15% of the patients include allergic conjunctivitis, conjunctival folliculosis, conjunctival hyperemia, eye pruritus, ocular burning, and stinging. 1 to 5% of the patients in clinical trials experienced asthenia, blepharitis, corneal erosion, depression, epiphora, eye discharge, eye dryness, eye irritation, eye pain, eyelid edema, eyelid erythema, eyelid pruritus, foreign body sensation, headache, hypertension, oral dryness,

title: Emedastine
text: to emedastine or any other excipients of the preparation. Benzalkonium chloride contained in the bottle of emedastine solution can discolor soft contact lenses, so people who wear contact lenses should be careful using it. The most common adverse effect was headache (11%). The other minor adverse effects encountered in less than 5% of patients were asthenia, burning or stinging sensation, unpleasant taste, blurred vision, eye dryness and tearing. Emedastine Emedastine (trade name Emadine) is a second generation antihistamine used in eye drops to alleviate the symptoms of allergic conjunctivitis. It acts as a H receptor antagonist. It works by blocking

title: Eye drop
text: cause stinging for one or two minutes when first used and if stinging continues, medical advice should be sought. Also, one should tell their doctor if vision changes occur or if they experience persistent sore throat, fever, easy bleeding or bruising when using drops with chloramphenicol. Also, one should be aware of symptoms of an allergic reaction, such as: rash, itching, swelling, dizziness, and trouble breathing. Prostaglandin analogs may cause changes in iris color and eyelid skin, growth of eyelashes, stinging, blurred vision, eye redness, itching, and burning. Beta blockers' side effects include low blood pressure, reduced pulse rate, fatigue,

title: Tiabendazole
text: disorders and decreasing weaning weight have been observed, also at high exposure. Effects on humans from use as a drug include nausea, vomiting, loss of appetite, diarrhea, dizziness, drowsiness, or headache; very rarely also ringing in the ears, vision changes, stomach pain, yellowing eyes and skin, dark urine, fever, fatigue, increased thirst and change in the amount of urine occur. Carcinogenic effects have been shown at higher doses. Intermediate arylamidine 2 is prepared by the dry HCl catalyzed addition of aniline to the nitrile function of 4-cyanothiazole (1). Amidine (2) is then converted to its "N"-chloro analog 3 by means

title: Visine
text: OCUHIST) (Naphazoline hydrochloride 0.025%, Pheniramine maleate 0.3%) VISINE MAXIMUM (Glycerin 0.2%, Hypromellose 0.36%, Polyethylene glycol 400 1.0%, Tetrahydrozoline HCI 0.05%) VISINE TOTALITY (Glycerin 0.2%, Hypromellose 0.36%, Polyethylene glycol 400 1.0%, Tetrahydrozoline HCI 0.05%, Zinc sulfate 0.25%) The effect of Visine causing upset gastrointestinal effects when being ingested is depicted in the movie "Wedding Crashers" where John Beckwith (portrayed by Owen Wilson) poisons Sack's (Bradley Cooper) drink, causing him to suffer all night. John Beckwith also uses the Visine several times over the course of the film to fake crying. This movie has gained notoriety for encouraging the deadly prank of

title: Tetryzoline
text: were given 2 drops of 0.5 mg/ml tetryzoline eye drops (0.025–0.05 mg) at 0, 4, 8 and 12 h. Within 24 h time window since the last dose, tetryzoline blood serum concentration of the subjects was 13.0–210.0 ng/ml and urine concentration was 11–400 ng/ml. Both reached their maximum about 9 h post last dose. These levels correspond to normal ocular use of tetryzoline. Higher concentrations may indicate misuse of the drug or poisoning. Chemically, tetryzoline is a derivative of imidazoline. It has two enantiomers. An urban legend suggests that tetryzoline can cause violent diarrhea if given orally, such as by

title: Oxymetazoline
text: Drug Administration for topical treatment of persistent facial erythema (redness) associated with rosacea in adults. Due to its vasoconstricting properties, oxymetazoline is also used to treat nose bleeds and eye redness due to minor irritation (marketed as Visine L.R. in the form of eye drops). Rebound congestion, or rhinitis medicamentosa, may occur. A 2006 review of the pathology of rhinitis medicamentosa concluded that use of oxymetazoline for more than three days may result in rhinitus medicamentosa and recommended limiting use to three days. In a submission to the Therapeutic Goods Administration, a Novartis representative concluded, "The justification was not based

title: Cefuroxime
text: injecting the eye with cefuroxime after cataract surgery will lower the chance of developing endophthalmitis after surgery. Cefuroxime is generally well-tolerated and its side effects are usually transient. If ingested after food, this antibiotic is both better absorbed and less likely to cause its most common side effects of diarrhea, nausea, vomiting, headaches/migraines, dizziness, and abdominal pain compared to most antibiotics in its class. Although a widely stated cross-allergic risk of about 10% exists between cephalosporins and penicillin, recent assessments have shown no increased risk for a cross-allergic reaction for cefuroxime and several other second-generation or later cephalosporins. In US

title: Capsaicin
text: pain to the skin and, if ingested in large amounts by adults or small amounts by children, can produce nausea, vomiting, abdominal pain, and burning diarrhea. Eye exposure produces intense tearing, pain, conjunctivitis, and blepharospasm. The primary treatment is removal from exposure. Contaminated clothing should be removed and placed in airtight bags to prevent secondary exposure. For external exposure, bathing the mucous membrane surfaces that have contacted capsaicin with oily compounds such as vegetable oil, paraffin oil, petroleum jelly (Vaseline), creams, or polyethylene glycol is the most effective way to attenuate the associated discomfort; since oil and capsaicin are both

title: Tetryzoline
text: an eye-drop topical solution containing tetryzoline. This results in that inmate almost immediately running to a porta-potty toilet and enduring violent diarrhea due to the poisoning. Tetryzoline Tetryzoline (INN, also known as tetrahydrozoline) a drug used in some over-the-counter eye drops and nasal sprays. Tetryzoline is an alpha agonist for alpha-2 receptor and imidazoline receptor I-1 agonist. Mainly due to its alpha-2 agonism it can constrict conjuctival blood vessels of the eye when taken in the form of eye drops. This relieves the redness of the eye caused by minor ocular irritants. To treat allergic conjunctivitis, tetryzoline can be combined