Question: What led to the downfall of the incan empire?

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question: What was the overall thing that led to the downfall of the incan empire?
short_answers: disease
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question: What specific thing led to the downfall of the Incan empire?
short_answers: smallpox
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question: What was the most devastating factor that led to the downfall of the incan empire?
short_answers: diseases
epidemic
context: The effects of smallpox on the Inca empire were even more devastating. Beginning in Colombia, smallpox spread rapidly before the Spanish invaders first arrived in the empire. The spread was probably aided by the efficient Inca road system. Smallpox was only the first epidemic. Other diseases, including a probable Typhus outbreak in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, and measles in 1618, all ravaged the Inca people.
question: What was the first epidemic leading to the downfall of the incan empire?
short_answers: smallpox
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question: What foreign power shift helped lead to the downfall of the incan empire?
short_answers: conquistadors
Spanish conquest

Answer: The downfall of the Incan Empire can be linked to both disease and Spanish conquistadors. The first epidemic was smallpox, followed by other diseases including a probable Typhus outbreak, influenza, diphtheria and measles all of which ravaged the Inca people. Likewise, the long-term effects of the arrival of the Spanish conquistadors on the population of South America were catastrophic. The Incan population suffered an exceptionally dramatic and rapid decline following contact with the Spanish.