different factors , especially genetic , effect individual attitude to regular physical activity in iranian traditional medicine .
our aim was to conduct a comparative revision and evaluation of the effect of genetic factors on physical activity in classic medicine and iranian traditional medicine .
in this study , we reviewed persian resources in the research center of traditional medicine at shiraz university of medical sciences .
we also evaluated the texts on physical activity and genetics in pubmed and google scholar .
the results of classical medicine revision showed the effect of especial genes on obesity and sedentary behavior .
it is also derived from iranian traditional medicine resources that physical activity and sedentary behavior is affected by individual mizaj .
the results showed that those with hot and cold mizaj have different genetic potentials in sedentary behavior and physical activity .
such categorization would be helpful in identifying illnesses due to sedentary life in special groups of people .
 background : different factors , especially genetic , effect individual attitude to regular physical activity in iranian traditional medicine . 
 it was believed that individual physical activity attitude is affected by mizaj too . 
 our aim was to conduct a comparative revision and evaluation of the effect of genetic factors on physical activity in classic medicine and iranian traditional medicine.methods:in this study , we reviewed persian resources in the research center of traditional medicine at shiraz university of medical sciences . 
 we also evaluated the texts on physical activity and genetics in pubmed and google scholar.results:the results of classical medicine revision showed the effect of especial genes on obesity and sedentary behavior . 
 it is also derived from iranian traditional medicine resources that physical activity and sedentary behavior is affected by individual mizaj.conclusion:the results showed that those with hot and cold mizaj have different genetic potentials in sedentary behavior and physical activity . 
 such categorization would be helpful in identifying illnesses due to sedentary life in special groups of people . 
 it would also allow designing dedicated treatment for each person . 