Abstract:
There is provided a therapeutic apparatus for photodynamic therapy that includes a hollow tube inserted into a living body; an unfolding part that is coupled to one end of the tube and is unfolded; a light irradiation part that is disposed in the unfolding part to irradiate light; and an operating part that is coupled to the other end of the tube to unfold the unfolding part, wherein the light irradiation part irradiates light when the unfolding part is unfolded. 
     The therapeutic apparatus for photodynamic therapy according to the present disclosure allows irradiation of light by unfolding tissues of the curved portion in the living body, using an unfolding part capable of being unfolded depending on the user&#39;s selection and the light irradiation part coupled to the unfolding part, there is an effect of allowing the use of the photodynamic therapy even in a portion that cannot be conventionally treated using the photodynamic therapy.

Description:
CROSS-REFERENCE TO RELATED APPLICATION 
       [0001]    This application is a National Stage of International Application No. PCT/KR2014/006901 filed Jul. 28, 2014 claiming priority from Korean Patent Application No. 10-2013-0088868 filed on Jul. 26, 2013, with the Korean Intellectual Property Office, the disclosure of which is incorporated herein by reference. 
     
    
     BACKGROUND 
       [0002]    The present disclosure relates to a therapeutic apparatus for removing the causative bacteria of the disease using a photodynamic therapy, and more specifically, to a therapeutic apparatus for photodynamic therapy that is available for a curved portion inside a human body (gastrointestinal tract). 
         [0003]    From the past, in the treatment of several pathogens, including bacteria, although the treatment has been performed mainly using antibiotics, according to the use of the antibiotics, recently, a death rate resulting from infection due to pathogen such as several kinds of bacteria (so-called super bacteria) exhibiting resistance to antibiotic has been tended. 
         [0004]    Meanwhile, when an antibiotic tolerance of a patient is low or when treatment using the antibiotics is difficult due to allergies to the antibiotics, there is a need for a development of new therapy capable of replacing antibiotics as a therapy against the pathogens. 
         [0005]    In order to solve these problems, a photodynamic therapy using light of a particular wavelength has been developed. However, in organs such as a gastrointestinal tract with many curved portions or wrinkles, since irradiation of light is difficult, a sufficient photodynamic therapy is not performed. For example, when considering the anatomy of the stomach, there was a problem in which the irradiation of light was not possible in the extremely curved portion as in  FIG. 1  illustrating a cross-sectional view and an endoscopic image of great curvature of stomach, or it was not possible to exhibit an effect even when the irradiation was possible. 
         [0006]    Although the therapeutic apparatus for photodynamic therapy according to the present disclosure uses antibiotics as a treatment of the existing microbes using the photodynamic therapy, it is intended to enhance the therapeutic effect by combining the photodynamic therapy with a patient who is not treated due to resistant to antibiotics or the existing antibiotic treatment. However, it is intended to allow the easy treatment of diseases generated from the causative bacteria in order to easily and sufficiently perform the irradiation of light to the curved portion in which the irradiation of light into the human body is difficult. To apply the photodynamic therapy to the curved portion, there is an urgent need for a development of a mechanism that unfolds the curved portion to a flat state to irradiate the light. 
         [0007]    The objects of the present disclosure are not limited to those mentioned above, and other problems which are not mentioned will be clearly understood by those skilled in the art from the following description. 
       SUMMARY 
       [0008]    An aspect of the present disclosure may include a tube that is inserted into a living body; a light irradiation part that is installed to be movable in and out of the tube and irradiates light in a state of being discharged to the outside of the tube; and an operating part that moves the light irradiation part to the inside and outside of the tube. 
         [0009]    A moving member movable inside the tube may be connected to a rear end of the light irradiation part. 
         [0010]    The light irradiation part may include a plurality of optical fiber bundles having leading ends radially unfolded while being discharged to the outside of the tube; and a fixing member in which a leading end is radially unfolded to both sides of the optical fiber bundle. 
         [0011]    The fixing member may be elastically supported by an elastic member that provides an elastic force in a direction in which the optical fiber bundle is unfolded. 
         [0012]    The moving member may include a rotating part in which the optical fiber bundle is connected to the leading end, the rotating part rotating together with the optical fiber bundle while being discharged to the outside of the tube; and a fixing part in which the rotating part is inserted into the inside and the fixing member is connected to the leading end. 
         [0013]    The operating part may rotate the rotating part in a state in which the optical fiber bundle is discharged to the outside of the tube. 
         [0014]    The operating part may control the rotational speed of the rotating part in response to an irradiation region in the living body. 
         [0015]    The operating part may include a first knob coupled to a rear end of the tube; and a second knob that is rotatably coupled to the first knob and is connected to the moving member. 
         [0016]    The sensing part that detects the rotation of the second knob or the contact of the first knob or the second knob may be coupled to the first knob and the second knob to control the operation of the light irradiation part. 
         [0017]    Another aspect of the present disclosure may include a hollow tube inserted into a living body; an unfolding part that is coupled to one end of the tube and is unfolded; a light irradiation part that is disposed in the unfolding part to irradiate light; and an operating part that is coupled to the other end of the tube to unfold the unfolding part, the light irradiation part may irradiate light when the unfolding part is unfolded. 
         [0018]    The unfolding part includes a plurality of unfolding frames that is inserted into the tube on one side and is coupled to a shaft disposed inside the tube; and variable panels to which the other sides of the plurality of unfolding frames are coupled by being spaced apart from each other, an elongated hole is formed on one side of the unfolding frame coupled to both sides of the variable panel of the plurality of unfolding frames so as to be spaced apart from the shaft, and a sliding rod connected to the operating part is inserted into the elongated hole, thereby making it possible to unfold the variable panel of the unfolding part depending on the position of the sliding rod of the elongated hole. 
         [0019]    The elongated hole of the unfolding frame coupled to one side of the variable panel may be formed in a direction facing the elongated hole of the unfolding frame coupled to the other side of the variable panel. 
         [0020]    On one side of the tube, a cylindrical cylinder to which the sliding load is coupled is inserted, and the cylinder may be connected to the operating part. 
         [0021]    One end of the variable panel may be formed in an arched shape or a straight line shape. 
         [0022]    The operating part may include a first knob coupled to the other end of the tube; and a second knob which is pivotally coupled to the first knob and is connected to the slide rod. 
         [0023]    The light irradiation part may be made up of a plurality of light sources coupled to the unfolding frame or the variable panel, a sensor configured to detect the rotation of the second knob or the contact of the first knob and the second knob may be coupled to one side of the first knob or the second knob, thereby controlling the operation of the light source. 
         [0024]    The unfolding part is configured to include a plurality of unfolding frames which is inserted into the tube at one side to exert elasticity and is made up of an elastic member connected to the operating part; and variable panels coupled to the other side of each unfolding frame to be spaced apart from each other, the elastic members of each unfolding frame is configured to be mutually unfolded or to approach by operation of the operating part, thereby allowing the unfolding operation and the folding operation of the variable panel. 
         [0025]    The elastic members of each unfolding frame may be formed in a twisted form or in a straight line form and may be arranged to intersect with each other. 
         [0026]    The therapeutic apparatus for photodynamic therapy according to the present disclosure allows irradiation of light by unfolding tissues of the curved portion in the living body, using an unfolding part capable of being unfolded depending on the user&#39;s selection and the light irradiation part coupled to the unfolding part, there is an effect of allowing the use of the photodynamic therapy even in a portion that cannot be conventionally treated using the photodynamic therapy. 
         [0027]    Effects of the present disclosure are not limited to those mentioned above, and other effects that haven not been mentioned will be clearly understood by those skilled in the art from the following description. 
     
    
     
       BRIEF DESCRIPTION OF DRAWINGS 
         [0028]    The above and other aspects, features and other advantages of the present disclosure will be more clearly understood from the following detailed description taken in conjunction with the accompanied drawings, in which: 
           [0029]      FIG. 1  is a schematic diagram illustrating a stomach of a person and an endoscopic photograph of great curvature of the stomach; 
           [0030]      FIG. 2  is a cross-sectional view of a therapeutic apparatus for photodynamic therapy according to an exemplary embodiment of the present disclosure; 
           [0031]      FIG. 3  is an exemplary view illustrating a state in which a light irradiation part is inserted into the tube; 
           [0032]      FIG. 4  is an exemplary view illustrating a state in which the light irradiation part is discharged to the outside of the tube; 
           [0033]      FIG. 5  is a cross-sectional view of a therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of the present disclosure; 
           [0034]      FIGS. 6A and 6B  illustrate operation diagrams of an unfolding part illustrated in  FIG. 5 ; 
           [0035]      FIGS. 7A through 7C  are plan views illustrating a state in which the unfolding part illustrated in  FIG. 5  is unfolded; 
           [0036]      FIGS. 8A and 8B  are cross-sectional views of a therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of the present disclosure; 
           [0037]      FIGS. 9A and 9B  are cross-sectional views of a therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of the present disclosure; and 
           [0038]      FIGS. 10A and 10B  are cross-sectional views of a therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of the present disclosure. 
       
    
    
     DETAILED DESCRIPTION 
       [0039]    Exemplary embodiments of the present disclosure will now be described in detail with reference to the accompanied drawings. 
         [0040]    The disclosure may, however, be exemplified in many different forms and should not be construed as being limited to the specific embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art. 
         [0041]    In the drawings, the shapes and dimensions of elements may be exaggerated for clarity, and the same reference numerals will be used throughout to designate the same or alike elements. 
         [0042]    Hereinafter, an exemplary embodiment of a therapeutic apparatus for photodynamic therapy according to the present disclosure will be described in detail with reference to the accompanied drawings. 
         [0043]      FIG. 2  is a cross-sectional view of a therapeutic apparatus for photodynamic therapy according to an exemplary embodiment of the present disclosure,  FIG. 3  is an exemplary view illustrating a state in which a light irradiation part is inserted into the tube, and  FIG. 4  is an exemplary view illustrating a state in which the light irradiation part is discharged to the outside of the tube. 
         [0044]    According to the illustrated configuration, the therapeutic apparatus for photodynamic therapy according to the present disclosure may include a tube  10  which is inserted into a living body; a light irradiation part  20  that is installed to be movable in and out of the tube  10  to irradiate light in a state of being discharged to the outside of the tube  10 ; and an operating part  30  that moves the light irradiation part  20  inside and outside of the tube  10 . 
         [0045]    The tube  10  is inserted into a living body, and for example, it is desirable to perform the photodynamic therapy, by being inserted into the curved sites or concavo-convex sites (mucosal wrinkle sites) of the inner wall of the living body, such as a gastrointestinal tract. 
         [0046]    A moving member  12  is movably mounted inside the tube  10 . The moving member  12  is moved inside the tube  10  by the operating part  30 , and the moving member  12  is connected to the rear end of the light irradiation part  20 . Therefore, when the moving member  12  is moved by the operating part  30 , the light irradiation part  20  is moved into and out of the tube  10  in conjunction with this movement. Furthermore, the moving member  12  is usually elastic and can be formed in a rod-like shape that is easily bent. 
         [0047]    The moving member  12  can desirably include a tube-shaped fixing part  14 , and a rotating part  16  inserted into the fixing part  14 . The rotating part  16  is a part in which optical fiber bundles  22  of the light irradiation part  20  are connected, and serves to rotate the optical fiber bundles  22  in a state in which the light irradiation part  20  is moved to the outside of the tube  10 . The rotating part  16  is desirably provided only at the leading end of the tube  10  rather than being provided over the entire tube  10 , and can rotate by receiving the transmitted power via an electric wire connected to the rear end. 
         [0048]    Meanwhile, the light irradiation part  20  can be provided with a light source such as an LED capable of irradiating the light of a particular frequency, depending on the bacteria, and in this embodiment, it is desirably made up of a plurality of optical fibers bundles  22 . Of course, in this embodiment, although the light irradiation part  20  has been described as being made up of the optical fiber bundles  22 , it is not necessarily limited thereto. 
         [0049]    As illustrated in  FIG. 4 , the leading ends of the optical fiber bundles  22  are desirably radially unfolded, while being discharged to the outside of the tube  10 . Thus, when configuring the optical fiber bundles  22  so as to be unfolded on the outside of the tube  10 , it is also possible to more effectively irradiate the curved portion in the living body with light. 
         [0050]    Further, in this embodiment, when the optical fiber bundles  22  are discharged to the outside of the tube  10  (see  FIG. 4 ), the leading ends are configured to be radially unfolded, and when inserted into the tube  10  (see  FIG. 3 ), it is configured to maintain a pursed shape by the inner wall of the tube  10 . Therefore, when the user inserts the tube  10  into a living body, the optical fiber bundles  22  are inserted into the interior of the tube  10  and are easily inserted into the irradiation site, and when reaching the irradiation site the optical fiber bundles  22  are discharged to the outside of the tube  10  to irradiate light. 
         [0051]    Meanwhile, the light irradiation part  20  may further include fixing members  24   a  that are each rotatably mounted to both sides of the optical fiber bundle  22 . The fixing members  24  are connected to the leading end of the fixing part  14  of the moving member  12 , and serve to evenly unfold the curved portion or uneven portion (mucosal fold) of the inner wall of a living body such as a gastrointestinal tract. That is, the fixing member  24  is a rod shape with a tension that is unfolded, while being discharged to the outside of the tube  10 , and the optical fiber bundles  22  can be radially unfolded between both fixing members  24 , while maintaining the curved portion or uneven portion in an unfolded state. 
         [0052]    The end of the fixing member  24  connected to the moving member  12  can be elastically supported by an elastic member such as a torsion spring so that the fixing member  24  more evenly unfolds the curved portion. In this way, it is possible to more evenly unfold the fixing member  24  into the curved portions of the living body interior wall, by providing an elastic force in a direction in which the optical fiber bundles  22  are unfolded by the elastic member. 
         [0053]    Next, the operating part  30  can be operated to rotate the rotating part  16  of the moving member  12  (the fixing part  14  is not operated) in a state in which the light irradiation part  20  is discharged to the outside of the tube  10 . Thus, when the optical fiber bundles  20  is rotated together with the rotating part  16 , it is possible to more effectively irradiate the curved portion in the living body with light. In other words, when the optical fiber bundles  22  rotate in an unfolded state, since the optical fiber bundles  22  can come into contact with each of the surfaces of the curved portions in the living body, a more effective therapeutic treatment is possible. 
         [0054]    At this time, the operating part  30  is capable of controlling the rotational speed of the rotating part  16 , depending on the light irradiation area of the living body. For example, in the case of the wide light irradiation area, the operating part  30  increases the rotational speed to more widely unfold the optical fiber bundles  22 . In the case of the narrow light irradiation area, the operating part  30  decreases the rotational speed so that the optical fiber bundles  22  can concentrically irradiate light to a narrow area. 
         [0055]    Meanwhile, the operating part  30  can include a first knob  32  coupled to the rear end of the tube  10 ; and a second knob  34  that is rotatably coupled to the first knob  32  and is connected to the moving member  12 . A user can rotate the second knob  34 , by pursing the fingers after gripping the first knob  32  and the second knob  34  between palm and fingers, and the rotating part  16  can rotate, while the moving member  12  is moved front and back by this action. 
         [0056]    Also, a sensing part (not illustrated) for sensing the rotation of the second knob  34  or the contact between the first knob  34  and the second knob  32  may be coupled to the first knob  32  or the second knob  34  to control the operation of the light irradiation part  20 . For example, the sensing part detects the contact between the first knob  32  and the second knob  34  when a user rotates the second knob  34 , and may perform control so that the optical fiber bundle  22  emits light. 
         [0057]    Hereinafter, another exemplary embodiment of a therapeutic apparatus for photodynamic therapy according to the present disclosure will be described in detail with reference to the accompanied drawings. 
         [0058]      FIG. 5  is a cross-sectional view of a therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of the present disclosure,  FIGS. 6A and 6B  are operation diagrams of an unfolding part illustrated in  FIG. 5 , and  FIGS. 7A through 7   c  are plan views illustrating a state in which the unfolding part illustrated in  FIG. 5  is unfolded. 
         [0059]    Referring to these drawings, the therapeutic apparatus for photodynamic therapy according to another exemplary embodiment of present disclosure includes a hollow tube  100  inserted into a living body, an unfolding part  200  that is coupled to one end of the tube  100  and is unfolded, a light irradiation part  200  that is disposed in the unfolding part  200  to irradiate light, and an operating portion  400  that is coupled to the other end of the tube  100  to unfold the unfolding portion  200 . 
         [0060]    The tube  100  is inserted into a living body, a through-hole through which one end and the other end communicate with each other is formed inside the tube, and the unfolding part  200  and the operating part  400  are coupled to one end of the tube  100  to operate the unfolding part  200 . Thus, after one side of the tube  100  to which the unfolding part  200  is coupled is inserting into a living body, the operating part  400  is operated to unfold the unfolding part  200 . 
         [0061]    At this time, the light irradiation part  300  is disposed in the unfolding part  200  to be able to irradiate light, when the unfolding part  200  is unfolded. 
         [0062]    The unfolding part  200  according to the present disclosure will more specifically be described below with reference to  FIGS. 6A and 6B , and  FIGS. 7A through 7C . 
         [0063]    The unfolding part  200  includes a plurality of unfolding frames  210  coupled to the shaft  100  coupled to the tube  100  so as to be rotated by being inserted into one side of the tube  100 , and a variable panel  220  to which distal ends of the plurality of unfolding frames  210  are coupled to be spaced apart from each other. 
         [0064]    The unfolding frame  210  is configured to be able to support the entire unfolding part  200 , in the unfolding frame  210  formed at both ends of the plurality of unfolding frames  210 , an elongated hole  213  in the other direction spaced from the shaft  110  coupled to the tube  100  is formed. The sliding rod  215  connected to an operating part  400  is inserted into the elongated hole  213 , and rotates the unfolding frame  210  coupled to both ends of the variable panel  220  of the plurality of unfolding frames  210  around the shaft  110 , along the direction of movement of the sliding rod  215 . Thus, the variable panel  220  is unfolded when rotating of the unfolding frame  210  coupled to both ends. 
         [0065]    When pressing the unfolded variable panel  220  to be in contact with the curved portion in a living body in this state, when unfolding the variable panel  220  after bringing the variable panel  220  into contact with the curved portion in the folded state of the variable panel  220 , the living body portion of the curved portion is unfolded so that the light irradiation is possible. 
         [0066]    The elongated hole  213  of the unfolding frame  210  coupled to both ends of the variable panel  220  of the plurality of unfolding frames  210  coupled to the variable panel  220  is formed in directions opposite to each other as in  FIG. 3 , and is desirably configured so that the variable panel  220  can be unfolded when the sliding rod  215  moves in the direction of the operating portion  400 . 
         [0067]    Although the sliding rod  215  itself may be connected to the operating portion  400 , it should be configured so that the same tension is applied to both ends of the sliding rod  215 , when the sliding rod  215  itself is connected to the operating part  400 . However, in this case, since the connection between the sliding rod  215  and the operating part  400  is complicated, a problem of difficulty in reliable operation may occur. Thus, it is preferable to insert the cylindrical cylinder  120  to which the sliding rod  215  is coupled into one side of the tube  100  as in  FIG. 3 , and it is preferable to connect the cylinder  120  to the operating part  400 . Further, an elastic body (not illustrated) can be coupled to the other side direction or one side direction of the cylinder  120  so that the cylinder  120  can be moved in the one side direction when an external force is not applied to the cylinder  120 . 
         [0068]    Although the operating part  400  can be configured to unfold the unfolding frame  210  by being formed into various shapes, the operating part  400  according to the present disclosure is desirably configured to include a first knob  410  that is coupled to the other end of the tube  100  so that a user can be easily used, and a second knob  420  that is pivotally coupled to the first knob  410  and is connected to the sliding rod  215 . Accordingly, it is desirably configured so that a user can rotate the second knob  420 , by pursing the fingers after gripping the first knob  410  and the second knob  420  between palm and fingers, and can rotate the sliding rod  215 . 
         [0069]    In this case, the second knob  420  is connected to the guide bar  430  extending through the tube  100 , and the guide bar  430  is connected to the sliding rod  215  or the cylinder  120 , during operation of each of the knobs  410  and  420 , it pulls the sliding rod  215  or the cylinder  120  or pushes the sliding rod to unfold the unfolding frame  210 , or purses the sliding rod to perform the unfolding/folding operations of the variable panel  220 . 
         [0070]    Referring to  FIGS. 7A  though  7 C, the light irradiation part  300  is made up of a plurality of light sources  310  coupled to the unfolding frame  210  or the variable panel  220 , and a sensor for sensing the rotation of the second knob  420  or the contact between the first knob  410  and the second knob  420  is desirably coupled to the one side of the first knob  410  or the second knob  420  to be able to control the operation of the light source  310 . 
         [0071]    An LED laser fiber or the like can be coupled to the light source  310  to be able to irradiate light of a particular frequency, depending on the causative bacteria, and can also be configured so that a laser is irradiated. The light source  310  is a light source used in a photodynamic therapy and is disclosed in advance in the technical field to which the present disclosure pertains, and thus, the detailed description thereof will be omitted. 
         [0072]    Since such a light source  310  is desirably configured to be irradiated only when the variable panel  220  is unfolded, it is desirably configured to detect the rotation of the second knob  420  or to be irradiated only when the first knob  410  and the second knob  420  come into contact with each other. Therefore, according to the embodiments, a sensor for sensing the rotation angle of the second knob  420 , a sensor for sensing the contact or alike can be used. 
         [0073]    Further, although one end of the variable panel  220  can be formed in various shapes, it can also be convexly formed in other side direction or can also be concavely in one side direction as in  FIGS. 7A to 7C  so that the curved portions in the body can be effectively unfolded, and may be formed in a straight line shape. 
         [0074]      FIGS. 8A and 8B , and  FIGS. 9A and 9B  illustrate still other examples of the present disclosure, and are configured to operate the variable panel  210  by introducing an elastic member  230  into the unfolding part  200 . 
         [0075]    First, the unfolding part  200  is made up of a plurality of unfolding frame  210  that exerts resilience by being inserted into the tube  100  on one side and includes an elastic member  230  connected to the operating part  400 , and variable panels  220  coupled to the other side of the unfolding frame  210  to be spaced apart from each other. 
         [0076]    Here, the elastic members  230  of the unfolding frame  210  are constituted in a twisted form or are configured in a straight line form and are disposed in the form of intersecting with each other. 
         [0077]    Furthermore, the one side of each elastic member  230  is exposed to the outside of the tube  100 , and an operating part (the guide bar  430  connected to the second knob  420  of the operating part  400 ) is connected to the other side. Thus, when operating the operating part, each elastic member  230  is pulled and drawn into the tube  100 , or is pulled out to unfold or purse the other sides of each unfolding frame  210 , thereby allowing the unfolding and the folding operation of the variable panel  220 . 
         [0078]    In this case, since the leading end of the tube  100  is in contact with the elastic member  230 , when the elastic member  230  is drawn into and drawn out of the tube  100 , it presses the elastic member  230 , thereby allowing such an operation. 
         [0079]    To this end, when the elastic member  230  is configured in a twisted form, each elastic member is initially arranged outside the tube as illustrated in  FIG. 8A  and in an outward convex state. 
         [0080]    At this time, when the guide bar  430  is pulled, the convex portions of each elastic member  230  are pressed by the pulled force and the leading end of the tube  100 , and are inverted in a concave form inside the tube, whereby each unfolding frame  210  becomes an unfolded state. 
         [0081]    In contrast, elastic member  230  is in a state in which the guide bar  430  is pressed and inverted is restored, while being exposed to the outward direction of the tube  100  and becomes its original position in a convex state, and at this time, each unfolding frame  210  is in parallel to each other and becomes the unfolded state. 
         [0082]    Meanwhile, when the respective elastic members  230  are configured in a straight line form as illustrated in  FIGS. 9A and 9B , and are disposed in a cross shape, they are configured to intersect with each other, and the cross points are connected by the shaft. 
         [0083]    Further, by introducing the support member  240  such as a spring into each elastic member  230 , they are pursed when drawn into the tube  10  and are unfolded when drawn out of the tube  100 . 
         [0084]    In this case, one end of each elastic member  230  is connected to the guide bar  430  of the operating part  300  and is operated according to the operation of each of the knobs  410  and  420 . 
         [0085]    At this time, when the elastic member  230  is drawn into the tube  100 , the support member  240  is compressed, and when the elastic member  230  is drawn out, the support member  240  is inflated, and one sides of each elastic member  230  are unfolded. 
         [0086]    In contrast, when the support member is not introduced, the intersection points of each elastic member  230  are fixed, and when one sides of each elastic member  230  are spaced at a predetermined interval in such a fixed state, when each of the elastic members  230  is drawn into the tube  100 , it is pursed, and when drawn out, it exerts the elasticity and is unfolded. 
         [0087]      FIGS. 10A and 10B  illustrate still another exemplary embodiment of the unfolding part  200  according to the present disclosure, sliding grooves  250  arranged in a manner corresponding to one another and forming a cross-shape when viewed from the side which is formed on the inner surface of the tube  100 , and the inner surfaces of the sliding grooves  250  are formed in a helical shape. 
         [0088]    Further, a first connecting member  260  having elasticity is provided at one ends of each unfolding frame  210 , and balls  270  connected to the end of the first connecting member  260  and inserted into the sliding grooves  250  are provided. 
         [0089]    Also, a second connecting member  280  having elasticity is connected to the guide bar  430  of the operating part  400 , and each ball  270  is connected to the second connecting member  280 . 
         [0090]    In the unfolding part  200  configured in this way, when pressing the respective knobs  410  and  420  of the operating part  400  to come close to each other, the guide bar  430  is pulled, and simultaneously, each ball  270  moves in the inward direction of the tube  100  while riding on the sliding grooves  250  by the second connecting member  280 , and the second connecting member  280  is in an inflated state. 
         [0091]    At this time, each ball  270  moves to intersect with each other along the sliding grooves  250 , and each unfolding frame  210  is gradually open by the first connecting member  260 , and the first connecting member  260  is also in an inflated state. 
         [0092]    When each ball  270  is moved and located at the distal end of the sliding groove  250 , the interval of each unfolding frame  210  is maximally open, and the variable panel  220  is completely unfolded. 
         [0093]    Furthermore, one ends of each unfolding frame  210  preferably rest on the leading end of the sliding groove  250  to be prevented from entering the sliding groove  250 , so that the unfolding operation of each unfolding frame  210  can be smoothly performed. 
         [0094]    In contrast, when the respective knobs  410  and  420  of the operating part  400  are open to be away from each other, the guide bar  430  is pulled, and simultaneously, the inflated second connecting member  280  shrinks, and at this time, the first connecting member  260  also shirks, and each ball  270  moves in the outward direction of the tube  100 , while riding on the sliding groove  250 . 
         [0095]    Thus, as each ball  270  moves in an outward direction of the tube  100  while riding on the sliding groove  250 , while each unfolding frame  210  is gradually folded, when each ball  270  is located at the leading end of the sliding groove  250 , the tube is completely folded, and simultaneously, the variable panel  220  is also folded. 
         [0096]    Furthermore, the leading end or the distal end or both ends of the sliding groove  250  are formed with receiving grooves  255  so that the balls  270  can sit thereon, and when the balls  170  are located at the leading end and the distal end, the grooves can also preferably perform a stopper so that the balls can be stopped at that position. 
         [0097]    The exemplary embodiments described in the specification and the accompanied drawings merely exemplarily explain some of the technical ideas contained in the present disclosure. Thus, since the exemplary embodiments disclosed herein are intended to illustrate the technical spirit of the present disclosure rather than limit the same, it is obvious that the scope of the technical idea of the present disclosure is not limited by the exemplary embodiments. Modifications and specific examples that can be easily analogized within the scope of the technical idea included in the specification and the drawings of the present disclosure by those skilled in the art should be construed as being included in the scope of right of the present disclosure. 
         [0098]    While exemplary embodiments have been illustrated and described above, it will be apparent to those skilled in the art that modifications and variations could be made without departing from the spirit and scope of the present disclosure as defined by the appended claims.