Abstract:
The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods.

Description:
FIELD OF THE INVENTION 
     The present invention relates to ribosomal protein genes, the corresponding mRNA, and specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate yeast and fungal species. In particular, the present invention relates to the gene corresponding to the ribosomal protein RPS7 and its corresponding mRNA. 
     BACKGROUND TO THE INVENTION 
     Detection and identification of yeast and fungi as the cause of infections has never been more important. The numbers of immunocompromised patients at risk for yeast and fungal infection continues to increase, as does the spectrum of fungal agents causing disease. Mortality from fungal infections, particularly invasive fungal infections, is 30% or greater in certain at risk patient groups (“ Stakeholder Insight: Invasive fungal infections ”, Datamonitor, January 2004). The array of available antifungal agents is growing; however, so too is the recognition of both intrinsic and emerging resistance to antifungal drugs. These factors are contributing to the increased need for cost containment in laboratory testing and has led to laboratory consolidation in testing procedures. 
     Invasive fungal infections are on the increase. In 2003, it was estimated that there were 9 million at risk patients of which 1.2 million developed infection. Immunocompromised patients including transplant and surgical patients, neonates, cancer patients, diabetics and those with HIV/AIDs are at high risk of developing invasive fungal infections (Datamonitor report: Stakeholder opinion—Invasive fungal infections, options outweigh replacements 2004). A large number of severe sepsis are reported each year. Despite improvements in its medical management, sepsis still constitutes one of the greatest challenges in intensive care medicine. Micro-organisms (bacteria, fungi and yeast) responsible for causing sepsis are traditionally detected in hospital laboratories with the aid of microbiological culture methods with poor sensitivity (25-82%), which are very time-consuming, generally taking from two to five days to complete, and up to eight days for the diagnosis of fungal infections Definitive diagnosis is usually based on either the recovery and identification of a specific agent from clinical specimens or microscopic demonstration of fungi with distinct morphological features. 
     However, there are numerous cases where these methods fail to provide conclusive proof as to the infecting agent. In these instances, the detection of specific host antibody responses can be used, although again this can be affected by the immune status of the patient. Time is critical in the detection and identification of bloodstream infections typically caused by bacteria and fungi. Effective treatment depends on finding the source of infection and making appropriate decisions about antibiotics or antifungals quickly and efficiently. Only after pathogens are correctly identified can targeted therapy using a specific antibiotic begin. Many physicians would like to see the development of better in vitro amplification and direct detection diagnostic techniques for the early diagnosis of yeast and fungi (“ Stakeholder Insight: Invasive fungal infections ”, Datamonitor, January 2004). Recently Roche™ launched a real time PCR based assay (Septifast™), for the detection of bacterial, fungal and yeast DNA in clinical samples. Therefore there is a clear need for the development of novel rapid diagnostic tests for clinically significant bacterial and fungal pathogens for bioanalysis applications in the clinical sector. This has led us to the search and identify novel fungal and yeast nucleic acid targets for application in Nucleic Acid Diagnostisc (NAD) tests. 
       Candida  spp. and  Aspergillus  spp. now rank as the most prominent pathogens infecting immunosupressed patients. In particular, infections are common in the urinary tract, the respiratory system and the bloodstream, at the site of insertion of stents, catheters and orthopaedic joints. Approximately, 10% of the known  Candida  spp. have been implicated in human infection. Invasive candidiasis occurs when candida enters the bloodstream and it is estimated to occur at a frequency of 8/100,000 population in the US with a mortality rate of 40%.  Candida albicans  is the 4 th  most common cause of bloodstream infection. Aspergillosis usually begins as a pulmonary infection that can progress to a life-threatening invasive infection in some patients and has a mortality rate of greater than 90%. Emerging mycoses agents include  Fusarium, Scedosporium , Zygomycetes and  Trichosporon  spp. (“ Stakeholder Insight: Invasive fungal infections ”, Datamonitor, January 2004). 
     Fungal and yeast nucleic acid based diagnostics have focused heavily on the ribosomal RNA (rRNA) genes, RNA transcripts, and their associated DNA/RNA regions. The rRNA genes are highly conserved in all fungal species and they also contain divergent and distinctive intergenic transcribed spacer regions. Ribosomal rRNA comprises three genes: the large sub-unit gene (28S), the small sub-unit gene (18S) and the 5.8S gene. The 28S and 18S rRNA genes are separated by the 5.8S rRNA and two internal transcribed spacers (ITS1 and ITS2). Because the ITS region contains a high number of sequence polymorphisms, numerous researchers have concentrated their efforts on these as targets (Atkins and Clark, 2004). rRNA genes are also multicopy genes with &gt;10 copies within the fungal genome. 
     A number of groups are working on developing new assays for fungal and yeast infections. US2004044193 relates to, amongst a number of other aspects, the transcription factor CaTEC1 of  Candida albicans ; inhibitors thereof, and methods for the diagnosis and therapy of diseases which are connected with a  Candida  infection; and also diagnostic and pharmaceutical compositions which contain the nucleotide sequences, proteins, host cells and/or antibodies. WO0183824 relates to hybridization assay probes and accessory oligonucleotides for detecting ribosomal nucleic acids from  Candida albicans  and/or  Candida dubiniensis . U.S. Pat. Nos. 6,017,699 and 5,426,026 relate to a set of DNA primers which can be used to amplify and speciate DNA from five medically important  Candida  species. U.S. Pat. No. 6,747,137 discloses sequences useful for diagnosis of  Candida  infections. EP 0422872 and U.S. Pat. No. 5,658,726 disclose probes based on 18S rRNA genes, and U.S. Pat. No. 5,958,693 discloses probes based on 28S rRNA, for diagnosis of a range of yeast and fungal species. U.S. Pat. No. 6,017,366 describes sequences based on chitin synthase gene for use in nucleic acid based diagnostics for a range of  Candida  species. 
     It is clear though, that development of faster, more accurate diagnostic methods are required, particularly in light of the selection pressure caused by modern anti-microbial treatments which give rise to increased populations of resistant virulent strains with mutated genome sequences. Methods that enable early diagnosis of microbial causes of infection enable the selection of a specific narrow spectrum antibiotic or antifungal to treat the infection (Datamonitor report: Stakeholder opinion—Invasive fungal infections, options outweigh replacements 2004; Datamonitor report: Stakeholder Opinion-Sepsis, under reaction to an overreaction, 2006). 
     RPS7 is one of more than 70 ribosomal proteins. It is found in prokaryotes and eukaryotes and functions in the small ribosomal subunit in the folding of rRNA which forms the head of the small ribosomal subunit. The rps7 gene encodes an essential protein which has a conserved function within the ribosome. In yeasts, for example  Saccharomyces cerevisiae  RPS7 is encoded by two genes differing at 14 base pair positions with each gene having 1 intron. Synetos et al. (1992) showed that  Saccharomyces  could survive with one copy of the gene but that deletion of both was lethal. Delbrück et al. (1997) cloned and sequenced the rps7 gene in  C. albicans  (GenBank Accession number U37009), determining that rps7 in  C. albicans  lacked an intron and shared 83% homology at an amino acid level with the RPS7 protein in  S. cerevisiae . This group also showed that the rps7 gene was up-regulated during hyphal formation with expression levels 3-6 fold higher than rRNA. This suggests that the gene is clinically relevant as morphogenesis from yeast form to hyphal formation is important in  Candida  spp. infections. In  Aspergillus  spp. in particular  A. fumigatus , the rps7 gene contains 3 exons and 2 introns and therefore the structure of the gene is different from those found in yeasts. 
     It is therefore an object of the invention to provide sequences and/or diagnostic assays that may be used in detection and identification of one or more yeast or fungal species. The present inventors have exploited the structural organization of the rps7 gene to design  Candida  and  Aspergillus  gene-specific primers. This has an advantage over the prior art in that if one wants to identify a fungal pathogen in a sample which contains  Candida  as a commensal, the approach of using universal primers may not be successful. There is a strong possibility that the  Candida  will out-compete the fungal pathogen in the amplification process and will be preferentially amplified, resulting in failure to detect the disease-causing pathogen. Furthermore, it has been suggested by Delbrück et al. 1997 that the sequence differences between different alleles of the rps7 gene on different chromosomes in one species may be even greater than differences between genes in different related asexual species. This would lead the skilled person away from selecting this gene as a target for molecular diagnostics. Also, different sequence types exist for some species, such as  Candida albicans , which would also lead one away from selecting this gene as a target gene for molecular diagnostics. 
     DEFINITIONS 
     As used herein, the following terms have the given meanings unless expressly stated to the contrary. 
     “Synthetic oligonucleotide” refers to molecules of nucleic acid polymers of 2 or more nucleotide bases that are not derived directly from genomic DNA or live organisms. The term synthetic oligonucleotide is intended to encompass DNA, RNA, and DNA/RNA hybrid molecules that have been manufactured chemically, or synthesized enzymatically in vitro. 
     An “oligonucleotide” is a nucleotide polymer having two or more nucleotide subunits covalently joined together. Oligonucleotides are generally about 10 to about 100 nucleotides. The sugar groups of the nucleotide subunits may be ribose, deoxyribose, or modified derivatives thereof such as OMe. The nucleotide subunits may be joined by linkages such as phosphodiester linkages, modified linkages or by non-nucleotide moieties that do not prevent hybridization of the oligonucleotide to its complementary target nucleotide sequence. Modified linkages include those in which a standard phosphodiester linkage is replaced with a different linkage, such as a phosphorothioate linkage, a methylphosphonate linkage, or a neutral peptide linkage. Nitrogenous base analogs also may be components of oligonucleotides in accordance with the invention. 
     A “target nucleic acid” is a nucleic acid comprising a target nucleic acid sequence. A “target nucleic acid sequence,” “target nucleotide sequence” or “target sequence” is a specific deoxyribonucleotide or ribonucleotide sequence that can be hybridized to a complementary oligonucleotide. 
     An “oligonucleotide probe” is an oligonucleotide having a nucleotide sequence sufficiently complementary to its target nucleic acid sequence to be able to form a detectable hybrid probe:target duplex under high stringency hybridization conditions. An oligonucleotide probe is an isolated chemical species and may include additional nucleotides outside of the targeted region as long as such nucleotides do not prevent hybridization under high stringency hybridization conditions. Non-complementary sequences, such as promoter sequences, restriction endonuclease recognition sites, or sequences that confer a desired secondary or tertiary structure such as a catalytic active site can be used to facilitate detection using the invented probes. An oligonucleotide probe optionally may be labelled with a detectable moiety such as a radioisotope, a fluorescent moiety, a chemiluminescent, a nanoparticle moiety, an enzyme or a ligand, which can be used to detect or confirm probe hybridization to its target sequence. Oligonucleotide probes are preferred to be in the size range of from about 10 to about 100 nucleotides in length, although it is possible for probes to be as much as and above about 500 nucleotides in length, or below 10 nucleotides in length. 
     A “hybrid” or a “duplex” is a complex formed between two single-stranded nucleic acid sequences by Watson-Crick base pairings or non-canonical base pairings between the complementary bases. “Hybridization” is the process by which two complementary strands of nucleic acid combine to form a double-stranded structure (“hybrid” or “duplex”). 
     A “fungus” or “yeast” is meant any organism of the kingdom Fungi, and preferably, is directed towards any organism of the phylum Ascomycota and most preferably is directed towards any organism of the class Hemiascomycetes. 
     “Complementarity” is a property conferred by the base sequence of a single strand of DNA or RNA which may form a hybrid or double-stranded DNA:DNA, RNA:RNA or DNA:RNA through hydrogen bonding between Watson-Crick base pairs on the respective strands. Adenine (A) ordinarily complements thymine (T) or uracil (U), while guanine (G) ordinarily complements cytosine (C). 
     The term “stringency” is used to describe the temperature, ionic strength and solvent composition existing during hybridization and the subsequent processing steps. Those skilled in the art will recognize that “stringency” conditions may be altered by varying those parameters either individually or together. Under high stringency conditions only highly complementary nucleic acid hybrids will form; hybrids without a sufficient degree of complementarity will not form. Accordingly, the stringency of the assay conditions determines the amount of complementarity needed between two nucleic acid strands forming a hybrid. Stringency conditions are chosen to maximize the difference in stability between the hybrid formed with the target and the non-target nucleic acid. 
     With “high stringency” conditions, nucleic acid base pairing will occur only between nucleic acid fragments that have a high frequency of complementary base sequences (for example, hybridization under “high stringency” conditions, may occur between homologs with about 85-100% identity, preferably about 70-100% identity). With medium stringency conditions, nucleic acid base pairing will occur between nucleic acids with an intermediate frequency of complementary base sequences (for example, hybridization under “medium stringency” conditions may occur between homologs with about 50-70% identity). Thus, conditions of “weak” or “low” stringency are often required with nucleic acids that are derived from organisms that are genetically diverse, as the frequency of complementary sequences is usually less. 
     ‘High stringency’ conditions are those equivalent to binding or hybridization at 42° C. in a solution consisting of 5×SSPE (43.8 g/l NaCl, 6.9 g/l NaH 2 PO 4 H 2 O and 1.85 g/l EDTA, ph adjusted to 7.4 with NaOH), 0.5% SDS, 5×Denhardt&#39;s reagent and 100 μg/ml denatured salmon sperm DNA followed by washing in a solution comprising 0.1×SSPE, 1.0% SDS at 42° C. when a probe of about 500 nucleotides in length is used. 
     “Medium stringency’ conditions are those equivalent to binding or hybridization at 42° C. in a solution consisting of 5×SSPE (43.8 g/l NaCl, 6.9 g/l NaH 2 PO 4 H 2 O and 1.85 g/l EDTA, pH adjusted to 7.4 with NaOH), 0.5% SDS, 5×Denhardt&#39;s reagent and 100 μg/ml denatured salmon sperm DNA followed by washing in a solution comprising 1.0×SSPE, 1.0% SDS at 42° C., when a probe of about 500 nucleotides in length is used. 
     ‘Low stringency’ conditions are those equivalent to binding or hybridization at 42° C. in a solution consisting of 5×SSPE (43.8 g/l NaCl, 6.9 g/l NaH 2 PO 4 H 2 O and 1.85 g/l EDTA, pH adjusted to 7.4 with NaOH), 0.1% SDS, 5×Denhardt&#39;s reagent [50×Denhardt&#39;s contains per 500 ml: 5 g Ficoll (Type 400, Pharamcia), 5 g BSA (Fraction V; Sigma)] and 100 μg/ml denatured salmon sperm DNA followed by washing in a solution comprising 5×SSPE, 0.1% SDS at 42° C., when a probe of about 500 nucleotides in length is used. 
     In the context of nucleic acid in-vitro amplification based technologies, “stringency” is achieved by applying temperature conditions and ionic buffer conditions that are particular to that in-vitro amplification technology. For example, in the context of PCR and real-time PCR, “stringency” is achieved by applying specific temperatures and ionic buffer strength for hybridisation of the oligonucleotide primers and, with regards to real-time PCR hybridisation of the probe/s, to the target nucleic acid for in-vitro amplification of the target nucleic acid. 
     “High stringency” when used in reference to in vitro amplification based detection systems, for example in PCR and real-time PCR, comprise conditions of a hybridisation (annealing) temperature in the range of 55° C. to 65° C. in a buffer environment containing MgCl 2  at a concentration of 1.5-8 mM. 
     “Medium stringency” when used in reference to in vitro amplification based detection systems for example in PCR and real-time PCR, comprise conditions of a hybridisation (annealing) temperature in the range of 45° C. to 54° C. in a buffer environment containing MgCl 2  at a concentration of 1.5-8 mM. 
     “Low stringency” when used in reference to in vitro amplification based detection systems for example in PCR and real-time PCR, comprise conditions of a hybridisation (annealing) temperature in the range of 40° C. to 44° C. in a buffer environment containing MgCl 2  at a concentration of 1.5-8 mM. 
     One skilled in the art will understand that substantially corresponding probes of the invention can vary from the referred-to sequence and still hybridize to the same target nucleic acid sequence. This variation from the nucleic acid may be stated in terms of a percentage of identical bases within the sequence or the percentage of perfectly complementary bases between the probe and its target sequence. Probes of the present invention substantially correspond to a nucleic acid sequence if these percentages are from about 100% to about 80% or from 0 base mismatches in about 10 nucleotide target sequence to about 2 bases mismatched in an about 10 nucleotide target sequence. In preferred embodiments, the percentage is from about 100% to about 85%. In more preferred embodiments, this percentage is from about 90% to about 100%; in other preferred embodiments, this percentage is from about 95% to about 100% 
     By “sufficiently complementary” or “substantially complementary” is meant nucleic acids having a sufficient amount of contiguous complementary nucleotides to form, under high stringency hybridization conditions, a hybrid that is stable for detection. 
     By “nucleic acid hybrid” or “probe:target duplex” is meant a structure that is a double-stranded, hydrogen-bonded structure, preferably about 10 to about 100 nucleotides in length, more preferably 14 to 50 nucleotides in length, although this will depend to an extent on the overall length of the oligonucleotide probe. The structure is sufficiently stable to be detected by means such as chemiluminescent or fluorescent light detection, autoradiography, electrochemical analysis or gel electrophoresis. Such hybrids include RNA:RNA, RNA:DNA, or DNA:DNA duplex molecules. 
     “RNA and DNA equivalents” refer to RNA and DNA molecules having the same complementary base pair hybridization properties. RNA and DNA equivalents have different sugar groups (i.e., ribose versus deoxyribose), and may differ by the presence of uracil in RNA and thymine in DNA. The difference between RNA and DNA equivalents do not contribute to differences in substantially corresponding nucleic acid sequences because the equivalents have the same degree of complementarity to a particular sequence. 
     By “preferentially hybridize” is meant that under high stringency hybridization conditions oligonucleotide probes can hybridize their target nucleic acids to form stable probe:target hybrids (thereby indicating the presence of the target nucleic acids) without forming stable probe:non-target hybrids (that would indicate the presence of non-target nucleic acids from other organisms). Thus, the probe hybridizes to target nucleic acid to a sufficiently greater extent than to non-target nucleic acid to enable one skilled in the art to accurately detect the presence of (for example  Candida ) and distinguish these species from other organisms. Preferential hybridization can be measured using techniques known in the art and described herein. 
     By “theranostics” is meant the use of diagnostic testing to diagnose the disease, choose the correct treatment regime and monitor the patient response to therapy. The theranostics of the invention may be based on the use of an NAD assay of this invention on samples, swabs or specimens collected from the patient. 
     SUMMARY OF THE INVENTION 
     The present invention provides a diagnostic kit for detection and identification of yeast and/or fungal species comprising an oligonucleotide probe capable of binding to at least a portion of the RPS7 gene or its corresponding mRNA. The oligonucleotide probe may have a sequence substantially homologous to or substantially complementary to a portion of the RPS7 gene or its corresponding mRNA. It will thus be capable of binding or hybridizing with a complementary DNA or RNA molecule. The RPS7 gene may be a fungal RPS7 gene. The RPS7 gene may be a yeast RPS7 gene. The nucleic acid molecule may be synthetic. The kit may comprise more than one such probe. In particular the kit may comprise a plurality of such probes. In addition the kit may comprise additional probes for other organisms, such as, for example, bacterial species or viruses. 
     The RPS7 gene codes for the ribosomal protein S7 which is a protein component of the small ribosomal subunit in yeast and fungi. It is required for ribosomal biogenesis and hence for protein synthesis. RPS7 is involved in the initiation of assembly of the 18S rRNA. 
     The present invention has identified high copy number mRNAs for use in yeast and fungal diagnostics. The identified sequences are suitable not only for in vitro DNA/RNA amplification based detection systems but also for signal amplification based detection systems. 
     Furthermore the sequences of the invention identified as suitable targets provide the advantages of having significant intragenic sequence heterogeneity in some regions, which is advantageous and enables aspects of the invention to be directed towards group or species-specific targets, and also having significant sequence homogeneity in some regions, which enables aspects of the invention to be directed towards genus-specific yeast and fungal primers and probes for use in direct nucleic acid detection technologies, signal amplification nucleic acid detection technologies, and nucleic acid in vitro amplification technologies for yeast and fungal diagnostics. The RPS7 sequences allow for multi-test capability and automation in diagnostic assays. 
     One of the advantages of the sequences of the present invention is that the intragenic RPS7 nucleotide sequence diversity between closely related yeast and fungal species enables specific primers and probes for use in diagnostics assays for the detection of yeast and fungi to be designed. The RPS7 nucleotide sequences, both DNA and RNA can be used with direct detection, signal amplification detection and in vitro amplification technologies in diagnostics assays. The RPS7 sequences allow for multi-test capability and automation in diagnostic assays. 
     The high copy number of the RPS7 mRNA provides an advantage for its use in diagnostics assays in combination with signal amplification detection technologies. Moreover, the labile nature of the RPS7 transcript allows this diagnostic target to be used in viability diagnostics assays. 
     The kit may further comprise a primer for amplification of at least a portion of the RPS7 gene. Suitably the kit comprises a forward and a reverse primer for a portion of the RPS7 gene. The portion of the RPS7 gene may be a portion of exon 3 of the  Aspergillus  RPS7 gene. Alternatively, the portion of the RPS7 gene may be equivalent to a portion of the region of the gene from base pair position 508 to base pair position 711 of the  C. albicans  RPS7 gene. Particularly preferred are kits comprising a probe for a portion of exon 3 of the  Aspergillus  RPS7 gene and a probe for a portion of the region of the gene equivalent to base pair position 508 to base pair position 711 of the  C. albicans  RPS7 gene. Equivalent regions to base pair position 508 to base pair position 711 can be found in other organisms, such as  Saccharomyces species  and  Cryptococcus neoformans , but not necessarily at position 508 to 711. The kit may also comprise additional probes. 
     The probe may have a sequence selected from the group the SEQ ID NO 1 through to SEQ ID NO 7, SEQ ID No 176 through to SEQ ID NO 189 and SEQ ID NO 378 through to SEQ ID NO 413 and SEQ ID NO 419 through to SEQ ID NO 448 or a sequence substantially homologous to or substantially complementary to those sequences which can also act as a probe for the RPS7 gene. 
     The kit may comprise at least one forward in vitro amplification primer and at least one reverse in vitro amplification primer, the forward amplification primer having a sequence selected from the group consisting of SEQ ID NO 8 through to SEQ 40, SEQ ID NO 414, SEQ ID NO 417, SEQ ID NO 418 or a sequence being substantially homologous or complementary thereto which can also act as a forward amplification primer, and the reverse amplification primer having a sequence selected from the group consisting of SEQ ID NO 3, SEQ ID NO 22 through to SEQ 49, SEQ ID NO 415 and SEQ ID NO 416 or a sequence being substantially homologous or complementary thereto which can also act as a reverse amplification primer. The diagnostic kit may be based on direct nucleic acid detection technologies, signal amplification nucleic acid detection technologies, and nucleic acid in vitro amplification technologies is selected from one or more of Polymerase Chain Reaction (PCR), Ligase Chain Reaction (LCR), Nucleic Acids Sequence Based Amplification (NASBA), Strand Displacement Amplification (SDA), Transcription Mediated Amplification (TMA), Branched DNA technology (bDNA) and Rolling Circle Amplification Technology (RCAT)), or other in vitro enzymatic amplification technologies. 
     The invention also provides a nucleic acid molecule selected from the group consisting of SEQ ID NO 1 through to SEQ ID NO 466 and sequences substantially homologous thereto, or substantially complementary to a portion thereof and having a function in diagnostics based on the RPS7 gene. The nucleic acid molecule may comprise an oligonucleotide having a sequence substantially homologous to or substantially complementary to a portion of a nucleic acid molecule of SEQ ID NO 1 through to SEQ ID NO 466. 
     The invention also provides a method of detecting a target organism in a test sample comprising the steps of:
         (i) Mixing the test sample with at least one oligonucleotide probe as defined above under appropriate conditions; and   (ii) hybridizing under high stringency conditions any nucleic acid that may be present in the test sample with the oligonucleotide to form a probe:target duplex; and   (iii) determining whether a probe:target duplex is present; the presence of the duplex positively identifying the presence of the target organism in the test sample.       

     The probe may have a sequence selected from the group consisting of SEQ ID NO 1 through to SEQ ID NO 49, SEQ ID NO 176 through to SEQ ID NO 189 and SEQ ID NO 378 through to SEQ ID NO 448 or a sequence substantially homologous to or substantially complementary to those sequences which can also act as a probe for the RPS7 gene. 
     The nucleic acid molecule and kits of the present invention may be used in a diagnostic assay to detect the presence of one or more yeast and/or fungal species, to measure yeast and/or fungal titres in a patient or in a method of assessing the efficacy of a treatment regime designed to reduce yeast and/or fungal titre in a patient or to measure yeast and/or fungal contamination in an environment. The environment may be a hospital, or it may be a food sample, an environmental sample e.g. water, an industrial sample such as an in-process sample or an end product requiring bioburden or quality assessment. 
     The kits and the nucleic acid molecule of the invention may be used in the identification and/or characterization of one or more disruptive agents that can be used to disrupt the RPS7 gene function. The disruptive agent may be selected from the group consisting of antisense RNA, PNA, and siRNA. 
     In some embodiments, the RPS7 gene is an  E. gossypil  gene. In some such embodiments, the RPS7 gene may be selected from the group consisting of: SEQ ID NO 54, SEQ ID NO 194, SEQ ID NO 212, or their respective mRNA equivalents, SEQ ID NO 55, SEQ ID NO 195, SEQ ID NO 213 or a portion thereof, or a sequence substantially homologous thereto, or substantially complementary to a portion of one or more sequences. 
     In some embodiments, the RPS7 gene is a  K. lactis  gene. In some such embodiments, the RPS7 gene may be selected from the group consisting of: SEQ ID NO 56, SEQ ID NO 196, SEQ ID NO 210, or their respective mRNA equivalents, SEQ ID NO 57, SEQ ID NO 197, SEQ ID NO 211 or a portion thereof, or a sequence substantially homologous thereto, or substantially complementary to a portion of one or more sequences. 
     In some embodiments, the RPS7 gene is a  D. hansenil  gene. In some such embodiments, the RPS7 gene may be selected from the group consisting of: SEQ ID NO 60, SEQ ID NO 200, SEQ ID NO 214, or their respective mRNA equivalents, SEQ ID NO 61, SEQ ID NO 201, SEQ ID NO 215 or a portion thereof, or a sequence substantially homologous thereto, or substantially complementary to a portion of one or more sequences. 
     In some embodiments of the invention, a nucleic acid molecule comprising a species-specific probe can be used to discriminate between species of the same genus. 
     For example,  Candida albicans  species specific probes may comprise oligonucleotides comprising sequences SEQ ID NO 6, SEQ ID NO 7 and SEQ ID NO 378 through SEQ ID NO 385 or a portion thereof, or a sequence substantially homologous thereto, or substantially complementary to a portion of one or more sequences. 
     The oligonucleotides of the invention may be provided in a composition for detecting the nucleic acids of yeast and fungal target organisms. Such a composition may also comprise buffers, enzymes, detergents, salts and so on, as appropriate to the intended use of the compositions. It is also envisioned that the compositions, kits and methods of the invention, while described herein as comprising at least one synthetic oligonucleotide, may also comprise natural oligonucleotides with substantially the same sequences as the synthetic nucleotide fragments in place of, or alongside synthetic oligonucleotides. 
     The invention also provides for an in vitro amplification diagnostic kit for a target yeast and/or fungal organism comprising at least one forward in vitro amplification primer and at least one reverse in vitro amplification primer, the forward amplification primer being selected from the group consisting of one or more of SEQ ID NO 8-40, SEQ ID NO 414, SEQ ID NO 417, SEQ ID NO 418 or a sequence being substantially homologous or complementary thereto which can also act as a forward amplification primer, and the reverse amplification primer being selected from the group consisting of one or more of SEQ ID NO 3, SEQ ID NO 22 through to SEQ ID NO 49, SEQ ID NO 415 and SEQ ID NO 416 or a sequence being substantially homologous or complementary thereto which can also act as a reverse amplification primer. 
     The invention also provides for a diagnostic kit for detecting the presence of a candidate yeast and/or fungal species, comprising one or more DNA probes comprising a sequence substantially complementary to, or substantially homologous to the sequence of the RPS7 gene of the candidate yeast and/or fungal species. The present invention also provides for one or more synthetic oligonucleotides having a nucleotide sequence substantially homologous to or substantially complementary to one or more of the group consisting of the RPS7 gene or mRNA transcript thereof, the yeast and or fungal RPS7 gene or mRNA transcript thereof, the yeast RPS7 gene or mRNA transcript thereof, one or more of SEQ ID NO 1-SEQ ID NO 466. 
     The nucleotide may comprise DNA. The nucleotide may comprise RNA. The nucleotide may comprise a mixture of DNA, RNA and PNA. The nucleotide may comprise synthetic nucleotides. The sequences of the invention (and the sequences relating to the methods, kits compositions and assays of the invention) may be selected to be substantially homologous to a portion of the coding region of the RPS 7 gene. The gene may be a gene from a target yeast or fungal organism. The sequences of the invention are preferably sufficient so as to be able form a probe:target duplex to the portion of the sequence. 
     The invention also provides for a diagnostic kit for a target yeast or fungal organism comprising an oligonucleotide probe substantially homologous to or substantially complementary to an oligonucleotide of the invention (which may be synthetic). It will be appreciated that sequences suitable for use as in vitro amplification primers may also be suitable for use as oligonucleotide probes: while it is preferable that amplification primers may have a complementary portion of between about 15 nucleotides and about 30 nucleotides (more preferably about 15-about 23, most preferably about 20 to about 23), oligonucleotide probes of the invention may be any suitable length. The skilled person will appreciate that different hybridization and or annealing conditions will be required depending on the length, nature &amp; structure (eg. Hybridization probe pairs for LightCycler, Taqman 5′ exonuclease probes, hairpin loop structures etc. and sequence of the oligonucleotide probe selected. Kits and assays of the invention may also be provided wherein the oligonucleotide probe is immobilized on a surface. Such a surface may be a bead, a membrane, a column, dipstick, a nanoparticle, the interior surface of a reaction chamber such as the well of a diagnostic plate or inside of a reaction tube, capillary or vessel or the like. 
     The target yeast or fungal organism may be selected from the group consisting of  C. albicans, C. glabrata, C. tropicalis, C. krusei, C. parapsilosis, C. dubliniensis, C. guillermondii, C. norvegiensis, C. lusitaniae, C. lipolytica, C. rugosa, C. catenulata, C. cifferi, C. famata, C. haemulonii, C. pulcherrima, C. utilis, C. kefyr, C. viswanthii, C. zealanoides. S. cerevisiae, C. neoformans, E. gossypii, K. Lactis, D. hansenii, Aspergillus nidulans, Aspergillus fumigatus Aspergillus terreus, A. versicolor, A. flavus, A. niger, A. candidus, A. clavatus, A. glaucus, Neosartorya fischeri  and  A. fischeri.    
     The target yeast organisms may be a  Candida  species for the given set of primers already experimentally demonstrated, and more preferably, selected from the group consisting of  C. albicans, C. glabrata, C. tropicalis, C. krusei, C. parapsilosis, C. dubliniensis, C. guillermondii, C. norvegiensis, C. lusitaniae, C. lipolytica, C. rugosa, C. catenulata, C. cifferi, C. famata, C. haemulonii, C. pulcherrima, C. utilis, C. kefyr, C. viswanthii, C. zealanoides . Under these circumstances, the amplification primers and oligonucleotide probes of the invention may be designed to a gene specific or genus specific region so as to be able to identify one or more, or most, or substantially all of the desired organisms of the target yeast organism grouping. Suitable forward amplification primers may be selected from the group consisting of: Can1F: 5′-AGC TGG TTT CAT GGA TGT-3′ (SEQ ID NO 40), SEQ ID NO 36, and SEQ ID NO 37, and/or, a mixture of SEQ ID NO 38 and 39. Suitable reverse amplification primer may be selected from the group consisting of Can2R: 5′-TCT GGG TAT CTG AT(A/G) GTT CT-3′ (SEQ ID NO 3), SEQ ID NO 2 and or a mixture of SEQ ID NOs 4 and 5, or indeed, oligonucleotides substantially complementary to one or more of SEQ ID NO 41, SEQ ID NO 42, SEQ ID NO 46, SEQ ID NO 47 and/or a mixture of SEQ ID NO 43-45, and/or a mixture of SEQ ID NO 48-49. Suitable genus-specific oligonucleotide probes are: CASP: 5′-TAA CAT CGT AGG CTA ATC-3′ (SEQ ID NO. 1), SEQ ID NO 6, or SEQ ID NO 7.  Candida  species specific probes may be selected from the group consisting of SEQ ID NO 378 through to SEQ ID NO 413. 
     The target fungal organisms may be an  Aspergillus  species for given set of primers already experimentally demonstrated, and more preferably, selected from the group consisting of  Aspergillus nidulans, Aspergillus fumigatus Aspergillus terreus, A. versicolor, A. flavus, A. niger, A. candidus, A. clavatus, A. glaucus, Neosartorya fischeri  and  A. fischeri . Suitable forward amplification primers may be SEQ ID NO 414, SEQ ID NO 417 and SEQ ID NO 418 with reverse primers selected may be SEQ ID NO 415 or SEQ ID NO 416.  Aspergillus  species specific probes may be selected from the group consisting of SEQ ID NO 419 through to SEQ ID NO 448. 
     The test sample may comprise cells of the target yeast and/or fungal organism. The method may also comprise a step for releasing nucleic acid from any cells of the target yeast or fungal organism that may be present in said test sample. Ideally, the test sample is a lysate of an obtained sample from a patient (such as a swab, or blood, urine, saliva, a bronchial lavage dental specimen, skin specimen, scalp specimen, transplant organ biopsy, stool, mucus, or discharge sample). The test samples may be a food sample, a water sample an environmental sample, an end product, end product or in-process industrial sample. 
     The invention also provides for the use of any one of SEQ ID NOs: 1-466 in a diagnostic assay for the presence of one or more yeast or fungal species. The species may be selected from the group consisting of  C. albicans, C. glabrata, C. tropicalis, C. krusei, C. parapsilosis, C. dubliniensis, C. guillermondii, C. norvegiensis, C. lusitaniae, C. lipolytica, C. rugosa, C. catenulata, C. cifferi, C. famata, C. haemulonii, C. pulcherrima, C. utilis, C. kefyr, C. viswanthii, C. zealanoides. S. cerevisiae, C. neoformans, E. gossypii, K. Lactis, D. hansenii, Aspergillus nidulans, Aspergillus fumigatus Aspergillus terreus, A. versicolor, A. flavus, A. niger, A. candidus, A. clavatus, A. glaucus, Neosartorya fischeri  and  A. fischeri.    
     The invention also provides for kits for use in theranostics, food safety diagnostics, industrial microbiology diagnostics, environmental monitoring, veterinary diagnostics, bio-terrorism diagnostics comprising one or more of the synthetic oligonucleotides of the invention. The kits may also comprise one or more articles selected from the group consisting of appropriate sample collecting instruments, reagent containers, buffers, labelling moieties, solutions, detergents and supplementary solutions. The invention also provides for use of the sequences, compositions, nucleotide fragments, assays, and kits of the invention in theranostics, Food safety diagnostics, Industrial microbiology diagnostics, Environmental monitoring, Veterinary diagnostics, Bio-terrorism diagnostics. 
     The nucleic acid molecules, composition, kits or methods may be used in a diagnostic nucleic acid based assay for the detection of yeast and/or fungal species. 
     The nucleic acid molecules, composition, kits or methods may be used in a diagnostic assay to measure yeast and/or fungal titres in a patient. The titres may be measured in vitro. 
     The nucleic acid molecules, composition, kits or methods may be used in a method of assessing the efficacy of a treatment regime designed to reduce yeast and/or fungal titre in a patient comprising assessing the yeast and/or fungal titre in the patient (by in vivo methods or in vitro methods) at one or more key stages of the treatment regime. Suitable key stages may include before treatment, during treatment and after treatment. The treatment regime may comprise an antifungal agent, such as a pharmaceutical drug. 
     The nucleic acid molecules, composition, kits or methods may be used in a diagnostic assay to measure potential yeast and/or fungal contamination, for example, in a hospital. 
     The nucleic acid molecules, composition, kits or methods may be used in the identification and/or characterization of one or more disruptive agents that can be used to disrupt the RPS7 gene function. Suitable disruptive agents may be selected from the group consisting of antisense RNA, PNA, siRNA. 
    
    
     
       BRIEF DESCRIPTION OF THE FIGURES 
         FIG. 1 : a: Gel electrophoresis of  Candida  species RT-PCR partial RPS7 sequence amplified using primers Can1F and Can2R; b: Autoradiograph demonstrating the specificity of the  C. albicans  species specific probe, CASP. A and B: lane 1: Marker XIV; 2:  Candida albicans  partial RPS7 RT-PCR product; 3:  C. tropicalis  partial RPS7 RT-PCR product; 4:  C. parapsilosis  partial RPS7 RT-PCR product; 5:  C. glabrata  partial RPS7 RT-PCR product; 6:  C. dubliniensis  partial RPS7 RT-PCR product. These in vitro amplified products were generated using the  Candida  genus specific primers Can1F: 5′-AGC TGG TTT CAT GGA TGT-3′: SEQ ID NO: 40. and Can2R: 5′-TCT GGG TAT CTG AT(A/G) GTT CT-3′: SEQ ID NO: 3. 
         FIG. 2 : Inclusivity testing of the real-time PCR assay for  C. albicans  based on rps7 gene and incorporating primers SEQ ID No 40 and SEQ ID NO 3 and TaqMan probe SEQ ID NO 384—all 20  C. albicans  strains detected. 
         FIG. 3 : Specificity of the real-time PCR assay for  C. albicans  based on rps7 gene and incorporating primers SEQ ID No 40 and SEQ ID NO 3 and TaqMan probe SEQ ID NO 384. Cross-check of other  Candida  species related to pathology including  C. haemuloni, C. kefyr, C. pulcherrima, C. utilis, C. viswanthii, C. zeylanoides  and human DNA—no cross reaction observed. 
         FIG. 4 : Limit of detection of the real-time PCR assay for  C. albicans  based on rps7 gene and incorporating primers SEQ ID No 40 and SEQ ID NO 3 and TaqMan probe SEQ ID NO 384 and including serial dilutions (10 6 -1 cell equivalent) of  C. albicans  genomic DNA —Detection limit 10 cells. 
         FIG. 5 : Limit of detection of the real-time PCR assay for  A. fumigatus  based on rps7 gene and incorporating primers SEQ ID No 418 and SEQ ID NO 415 and TaqMan probe SEQ ID NO 419 and including serial dilutions (10 6 -1 cell equivalent) of  A. fumigatus  genomic DNA 5062-Detection limit 1 cell equivalent. 
         FIG. 6 : Inclusivity testing of the real-time PCR assay for  A. fumigatus (20 strains of  A. fumigatus ) based on rps7 gene and incorporating primers SEQ ID No 418 and SEQ ID NO 415 and TaqMan probe SEQ ID NO 419—all  A. fumigatus  strains detected. 
         FIG. 7 : Specificity testing of the real-time PCR assay for  A. fumigatus  based on rps7 gene and incorporating primers SEQ ID No 418 and SEQ ID NO 415 and TaqMan probe SEQ ID NO 419. Cross-reactivity testing panel included a range of  Aspergillus  species-no cross reaction detected. 
     
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     Materials and Methods 
     Organism and growth conditions:  Candida  species (CBS 562) were grown on Sabouraud agar (4% wt/vol glucose, 1% wt/vol peptone, 1.5% agar) overnight at 37° C. @ 180 rpm. A single colony was used to inoculate 10 ml of Sabouraud broth (Oxoid™) and grown overnight @ 37° C. 1 ml of overnight culture was used to inoculate 100 ml Sabouraud broth (Oxoid™) and allowed to grow to exponential and stationary phases, 8 hrs and 16 hrs respectively.  Aspergillus niger  was grown on Sabouraud agar for 48 hrs @ 30° C. A hypodermic needle was used to stab the agar and transferred to 100 ml Sabouraud broth and allowed to grow for 48 hours.  Aspergillus  species from slope or dessicated stocks were also grown in Sabouraud agar at 25° C. for 1-7 days. 
     Total RNA isolation: RNA extraction from  C. albicans  was carried out following growth to exponential phase using the RNeasy™ Mini Kit™ (Qiagen™). 1 ml of culture was centrifuged @ 10,000 rpm and the pellet was resuspended in 100 μl of YI lysis buffer (0.1M EDTA, 1M sorbitol, 0.1% β-Mercaptoethanol and 1000 U lyticase) and incubated @ 30° C. for 20 mins. The quality of total RNA was assessed by gel electrophoresis on 1.2% MOPS denaturing gel and quantified by fluoroimetry using a TBS-380™ minifluorometer (Turner Systems™). 
     RPS7 Fungal/Yeast genus specific in vitro amplification primer design: Total RNA was isolated from five  Candida  species,  C. albicans, C. glabrata, C. tropicalis, C. parapsilosis  and  C. dubliniensis  using the Ambion™ Yeast total RNA isolation kit and this was carried out according to the manufacturers instructions. An in vitro RT-PCR amplification was then carried out on all five isolated total RNA&#39;s to demonstrate the use of Can 1F (SEQ ID NO. 40) and Can2R (SEQ ID NO. 3) for generating sequences from uncharacterized yeast species ( C. tropicalis, C. parapsilosis  and  C. dubliniensis ). RT-PCR amplification was carried out on the isolated total RNAs from all  Candida  species examined using the Titan One Tube™ RT-PCR System (Roche) according to the manufacturers instructions using the in vitro amplification primers SEQ ID NO. 3 and SEQ ID NO. 40. The resultant RT-PCR in vitro amplified products were then electrophoresed on 1.2% agarose gels to determine the success of in vitro amplification and subsequently Southern blotted ( FIG. 1A ). The remainder of the RT-PCR in vitro amplified products from the uncharacterized  Candida  RPS7 sequences were then purified using the Roche High Pure™ PCR product purification kit according to the manufacturers instructions and subsequently sequenced using SEQ ID NO. 40 as a sequencing primer to generate novel RPS7 partial sequence data for these organisms (SEQ ID 64 and 65, 66 and 67, 68 and 69, 70 and 71). 
     
       
         
               
             
               
               
             
               
             
               
               
             
           
               
                 SEQ ID NO: 40 
               
             
          
           
               
                   
                 Can1F: 5′-AGC TGG TTT CAT GGA TGT-3′:. 
               
               
                   
                   
               
             
          
           
               
                 SEQ ID NO: 3 
               
             
          
           
               
                   
                 Can2R: 5′-TCT GGG TAT CTG AT(A/G) GTT CT-3′:. 
               
             
          
         
       
     
     Determination of  Candida, S. cerevisiae  and  C. neoformans  species partial RPS7 sequences using the in vitro PCR amplification—primers CanF1 (SEQ NO: 40) and CanR2 (SEQ ID NO: 3): In order to determine and expand the nucleotide sequence database for the  Candida  species partial RPS7 sequences and also to further demonstrate the broad use of the in vitro PCR amplification primers CanF1 (SEQ ID NO 40) and Can2R(SEQ ID NO 3) a series of PCR in vitro amplifications were carried out on the following  Candida strains, C. albicans  strains, 178, 180, 320, 369, 765, 16733, 1560, 9559, 4154, 2700, 562, 3822, 3156, 3345, 3328,  C. dubliniensis  3949,  C. glabrata  strains, 9087, 4692, 205444, 10269, 9556, 5563, 3959, 138, 3605, 3897, 8018, 3863, 3902, 604,  C. parapsilosis  strains, 3902, 604, 2194, 2196, 1001, 1716, 9557, 5579,  C. krusei  strains 5579, 9560, 6055, 17518, 573, 3165, 3922, 3847, and  C. tropicalis  strains 3895, 94, 4225, 5557, 15902, 4139, 3873, 3870, 8157, 2311. Total genomic DNA was isolated from each of these strains using the Edge Biosystems Genomic DNA purification kit and the integrity of the purified DNA was determined by electrophoresis of each of the isolated DNA samples on a 1.2% agarose gel. Each DNA sample was then subjected to in vitro PCR amplification using Taq DNA polymerase (Roche) in combination with CanF1 and CanR2 according to the manufacturers instructions. The PCR product amplified from each  Candida  strain genomic DNA was then purified using the Roche High Pure PCR product purification kit. The purified PCR products were then subjected to nucleotide sequencing using CanF1 as a sequencing primer. This resulted in the generation of novel partial RPS7 nucleotide sequences for all  Candida  strains tested. Sequences represented by SEQ ID 62 through SEQ ID NO. 175 represents the partial RPS7 nucleotide sequence generated for  Candida  strains tested for and described above. In addition, PCR amplification primers SEQ ID NO 40 and SEQ ID NO 3 were used to amplify DNA extracted from  Candida  species (n=20 species n=120 strains). These primers amplify at 204 by region of the rps7 gene equivalent to position 508 to 711 of the rps7 gene in  C. albicans  (Accession no: U37009). DNA was extracted on the MagNA Pure System (Roche Molecular Systems) using the MagNA pure Yeast and Bacterial isolation kit III following a pre-treatment of the  Candida  spp. cells with lyticase enzyme. Some DNA extracts were obtained using the EasyMag system (BioMerieux). PCR amplification was performed using the reagents and conditions outlined in Table 1. The PCR products for DNA sequencing were cleaned up using the ExoSAP-IT kit (USB) or the High Pure PCR purification kit (Roche). DNA sequencing of PCR products for  Candida  spp. was undertaken by an external sequence service provider, Sequiserve (Germany) using the SEQ ID NO 40 primer. In addition, PCR primers SEQ ID NO 40 and SEQ ID NO 3 were used to amplify DNA from  C. neoformans  and  S. cerevisiae  species. The PCR products were also sequenced by the external sequence provider, Sequiserve (Germany) using the SEQ ID NO 40 primer. Sequences ID NO 222 through to SEQ ID NO 325 represent the  Candida  spp. rps 7 gene (204 bp) sequences. SEQ ID NO 449 represents the  S. cerevisiae  rps 7 gene (204 bp) sequence and SEQ ID NO 451 represents the  C. neoformans  rps 7 gene sequence. 
                                   TABLE 1                   PCR reagents and conditions used to amplify the rps7 gene in         Candida  spp.  S. cerevisiae  and  C. neoformans .            PCR               conditions:   Reaction conditions   Cycle parameters:               ICycler   1 μL each primer @ 17 μM   94° C. 1 min       (50 μL)   5 μl 10X Buffer (Roche) -   30 × 45° C. 1 min           [100 mM Tris-HCl, 15 mM MgCl 2 ,   72° C. 1 min           500 mM KCl, pH 8.3].           1 μl (IU) Taq Polymerase   72° C. 7 min           (Roche)           1 μl of stock dNTP mix           (10 mM of each dNTP)           2-5 μl DNA template       LightCycler   1 μL each primer @ 10 μM   1 × 40° C. 10 min       (20 μL)   2 μL FastStart Mix (HybProbe   1 × 95° C. 10 min           kit)           2.4 μL (4 mM) MgCl 2             0.5 μL (1 U) LightCycler UNG   95° C. −10 sec           2 μL DNA template   45 × 55° C. −30 sec               72° C. −1 min               Cooling 40° C.                    
Generation of RPS7 Gene Exon 3 Sequence Information for  Aspergillus  Species.
 
     PCR primers forward primer SEQ ID NO 414 and reverse primer SEQ ID NO SEQ 415 were designed to amplify exon 3 (317 bp) from position 664-980 in RPS7 in  A. fumigatus  GenBank Accession no: XM_749453 in  Aspergillus  spp. DNA from 8 species (n=67 strains-Table 2) were PCR amplified with these primers and sequence information of the exon 3 fragment was successfully obtained for these strains. An independent set of primers, forward primer SEQ ID NO 417 and reverse primer SEQ ID NO 416 were designed and applied to amplify RPS7 gene (exon 3-317 bp) in  A. niger  strains (n=10-Table 2). PCR amplification of the RPS7 exon 3-317 by in the  Aspergillus  spp. was performed with these primers on the iCycler (BioRad) using the conditions described in Table 3. PCR products for DNA sequencing were cleaned up using the High Pure PCR purification kit (Roche). DNA sequencing was performed by an external sequence service provider, Sequiserve (Germany) using the SEQ ID NO 414 and SEQ ID NO 417 (forward) primers. 
     
       
         
               
             
               
               
               
             
               
               
               
             
           
               
                 TABLE 2 
               
             
             
               
                   
               
               
                   Aspergillus  species and strains for which 
               
               
                 exon 3 of the RPS7 gene was sequenced. 
               
             
          
           
               
                   
                   
                 Number of strains 
               
               
                   
                 Species name 
                 sequenced 
               
               
                   
                   
               
             
          
           
               
                   
                 
                   A. fumigatus 
                 
                 20 
               
               
                   
                 
                   A. terreus 
                 
                 10 
               
               
                   
                 
                   A. versicolor 
                 
                 5 
               
               
                   
                 
                   A. nidulans 
                 
                 7 
               
               
                   
                 
                   A. flavus 
                 
                 10 
               
               
                   
                 
                   A. niger 
                 
                 10 
               
               
                   
                 
                   A. candidus 
                 
                 5 
               
               
                   
                 
                   A. clavatus 
                 
                 5 
               
               
                   
                 
                   A. glaucus 
                 
                 5 
               
               
                   
                   
               
             
          
         
       
     
     
       
         
               
             
               
               
               
             
           
               
                 TABLE 3 
               
             
             
               
                   
               
               
                 PCR reagents and PCR conditions used for PCR amplification 
               
               
                 of the 317 bp region of exon 3 of the RPS7 gene in 
               
               
                   Apergillus  spp. for DNA sequencing. 
               
             
          
           
               
                 PCR 
                   
                   
               
               
                 conditions: 
                 Reaction conditions 
                 Cycle parameters: 
               
               
                   
               
               
                 ICycler 
                 1 μL each primer @ 10 μM 
                 94° C. 1 min 
               
               
                 (50 μL) 
                 5 μl 10X Buffer (Roche) - 
                 30 × 50/52° C. 1 min 
               
               
                   
                 [100 mM Tris-HCl, 15 mM 
                 72° C. 1 min 
               
               
                   
                 MgCl 2 , 500 mM KCl, pH 8.3]. 
               
               
                   
                 1 μl (IU) Taq Polymerase 
                 72° C. 7 min 
               
               
                   
                 (Roche) 
               
               
                   
                 1 μl of stock dNTP mix 
               
               
                   
                 (10 mM of each dNTP) 
               
               
                   
                 2-5 μl DNA template 
               
               
                   
               
             
          
         
       
     
     Development of prototype species specific  C. albicans  Nucleic Acid Diagnostics (NAD) assay based on the RPS7 gene sequence: The new and already existing RPS7 sequence data (SEQ ID NO 62-SEQ ID NO 175) were then examined and a  C. albicans  species specific oligonucleotide probe (CASP, SEQ ID NO. 1) was identified and then synthesised for use in hybridizing to the Southern blot as described above. The CASP (SEQ ID NO. 1) oligonucleotide probe was radioactively 5′ end labelled with gamma P 32  using T4 Polynucleotide Kinase (Roche) and was then hybridised to the Southern blot for 2 hours at 55° C. The hybridisation fluid was removed and the blot was then washed twice in 6×SSC, 0.1% SDS at room temperature for 10 minutes followed by a high stringency wash in 6×SSC, 0.1% SDS at 55° C. for 1 minute. The blot was exposed to X-Ray film and autoradiography was carried out for 2 hours at −70° C.  FIG. 1B  shows that CASP species specific oligonucleotide probe only hybridises to the  C. albicans  RT-PCR in vitro amplified product, thus demonstrating the use and potential of the RPS7 nucleic acid sequence as a target for the detection of a yeast species of interest. 
                         CASP: 5′-TAA CAT CGT AGG CTA ATC-3′:   SEQ ID NO. 1            
Design of Oligonucleotide Probes for  Candida  Spp.
 
     The sequence information obtained for the rps7 gene 204 by target region in  Candida  spp. representing the different sequence types obtained for each species (SEQ ID NO 222 through to SEQ ID NO 325) were aligned and analysed using bioinformatics tools, including Clustal W and BLAST programs and oligonucleotide probes were designed for the identification of different  Candida  species. For  C. albicans  identification, oligonucleotide probes SEQ ID NO 378 through to SEQ ID NO 385 were designed. For  C. krusei  identification, oligonucleotide probes SEQ ID NO 386 through to SEQ ID NO 389 were designed. For  C. parapsilosis  identification, oligonucleotide probes SEQ ID NO 390 through to SEQ ID NO 393 were designed. For identification of  C. tropicalis , oligonucleotide probes, SEQ ID NO 394 through to SEQ ID NO 405 were designed. For  C. glabrata  identification, oligonucleotide probes SEQ ID NO 406 through to SEQ ID NO 413 were designed. 
     Nucleic acid diagnostics assays were designed for  Candida  spp using the primers SEQ ID NO 40 and SEQ ID NO 3 and oligonucleotide probes SEQ ID NO 378-SEQ ID NO 413. Examples of the assays developed include real-time PCR TaqMan assays for 5  Candida  species including  C. albicans, C. krusei, C. tropicalis, C. glabrata  and  C. parapsilosis . An example of the  C. albicans  assay includes primers SEQ ID NO 40 and SEQ ID NO 3 and oligonucleotide probe SEQ ID NO 384 ( FIG. 2 ). An example of assay for  C. krusei  includes primers SEQ ID NO 40 and SEQ ID NO 3 and probe SEQ ID NO 386. An example of an assay for  C. glabrata  includes primers SEQ ID NO 40 and SEQ ID NO 3 and probe SEQ ID NO 412. An example of an assay for  C. tropicalis  includes primers SEQ ID NO 40 and SEQ ID NO 3 and probe SEQ ID NO 400. An example of an assay for  C. parapsilosis  includes primers SEQ ID NO 40 and SEQ ID NO 3 and probe SEQ ID NO 392. These species-specific assays were configured on the LightCycler real-time PCR machine and performed using the conditions and reagents described in Table 4. Each species assay was tested for inclusivity with 20 strains of the species and for each species assay the relevant strains (n=20) were detected. Each species assay was tested for cross-reactivity against a panel of species including 19 species of  Candida,  24 species of other yeasts and dermatophytes, 9 species of  Aspergillus,  15 bacterial species and human DNA (Table 5). Each species assay only detected strains of the species it was designed to detect and there was no cross-reaction with DNA from other  Candida  spp.,  Aspergillus  species, other yeasts, dermatophytes, bacteria or human DNA.  FIG. 3  shows an example of a specificity study with the  C. albicans  species-specific assay. The limits of detection (LOD) or sensitivities of the assays were determined using 10-serial dilutions (10 6 -1 cell equivalent) of genomic DNA from the relevant species. Detection limits of 10 cell equivalents were established for each species assay.  FIG. 4  shows the detection limit obtained for the  C. albicans  assay. 
     
       
         
               
             
               
               
               
             
               
               
               
               
             
           
               
                 TABLE 4 
               
               
                   
               
               
                 PCR reagents and thermocycling conditions: 
               
               
                   
               
             
             
               
                   
               
             
          
           
               
                   
                 PCR reagents 
                 Reaction Mix per 20 μl reaction 
               
               
                   
                   
                 FastStart mix 2 μL(Roche LightCycler DNA 
               
               
                   
                   
                 Master HybProbe kit Cat no 12239272001) 
               
               
                   
                   
                 MgCl 2  3.2 μl 
               
               
                   
                   
                 Probe 2 μL (Final 0.2 μM) 
               
               
                   
                   
                 Primer 1 μL (Final 0.5 μM) 
               
               
                   
                   
                 Primer 1 μL (Final 0.5 μM) 
               
               
                   
                   
                 UNG 0.5 μL (Optional) 
               
               
                   
                   
                 H 2 O 8.3 μL (8.8 μL if UNG not being used) 
               
               
                   
                   
                 DNA template 2 μL 
               
             
          
           
               
                   
                 Thermocycling 
                 40° C. 600 sec 
                 −1 cycle 
               
               
                   
                 conditions 
                 95° C. 600 sec 
                 −1 cycle 
               
               
                   
                   
                 95° C. 10 sec 
                 45 cycles 
               
               
                   
                   
                 62° C. 60 sec 
               
               
                   
                   
                 40° C. −10 sec 
                 −1 cycle 
               
               
                   
                   
               
             
          
         
       
     
     Panel of species included for cross-reactivity testing in the  Candida species  and  A. fumigatus  assays. 
                                           A. fumigatus       A. terreus       A. candidus           A. versicolor       A. nidulans       A. flavus           A. glaucus       A. niger       A. clavatus           C. albicans       C. glabrata       C. krusei           C. parapsilosis       C. tropicalis       C. dubliniensis           C. guillermondii       C. lipolytica       C. lusitanie           C. norvegensis       C. rugosa       C. catenulata           C. cifferii       C. famata       C. haemuloni           C. keyfr       C. pulcherrima       C. utilis           C. viswanthii       C. zeylanoides       Cryptococcus neoformans           S. cerevisiae       T. asahii       R. mucilaginosa           M. furfur       B. capitatus       Acremonium spp.           B australiensis       B hawiiensis       C lunata           F solani       M circillenoides       M ramoissimus           P. variotti       P lilicinus       Penicillium chry           R oryzae       Sced. apiosporum       Sced. prolificans           Scop. Brevicaulis       H. capsulatum       M. canis           T. quickeanum       T. rubrum       S. aureus           P. mirabilis       E. coli       S. marcescens           P. aeruginosa       E. cloacae       C. freundii           E. faecalis       S. pneumoniae       S. maltophilia           K. pneumoniae       E. aerogenes       A. baumani           K. oxytoca       E. faecium     Human DNA                    
Design of Oligonucleotide Primers and Probes for  Aspergillus  Spp.
 
     Following DNA sequencing, the exon 3 RPS7 317 bp, sequence information generated for PCR products amplified from  Aspergillus  spp. representing the different sequence types obtained for each species (SEQ ID NO 326 through to SEQ ID NO 377) were aligned and analysed using bioinformatics tools, including Clustal W and BLAST programs. PCR primer SEQ ID NO 418 was designed for amplification of a 125 by region of the RPS7 gene in  A. fumigatus  and other  Aspergillus  spp. in combination with PCR primer SEQ ID NO 415. For the identification of  A. fumigatus , oligonucleotide probes SEQ ID NO 419 through to SEQ ID NO 424 were designed. For the identification of  A. candidus , oligonucleotide probes SEQ ID NO 425 through to SEQ ID NO 428 were designed. For the identification of  A. terreus , oligonucleotide probes SEQ ID NO 429 through to SEQ ID NO 432 were designed. For the identification of  A. versicolor , oligonucleotide probes SEQ ID NO 433 through to SEQ ID NO 436 were designed. For the identification of  A. nidulans , oligonucleotide probes SEQ ID NO 437 through to SEQ ID NO 440 were designed. For the identification of  A. flavus  and oligonucleotide probes SEQ ID NO 441 and SEQ ID NO 442 were designed. Oligonucleotide probes SEQ ID NO 443 through SEQ ID NO 448 were designed for the identification of  A. clavatus.    
     Nucleic Acid Based Diagnostic Assay for  Aspergillus  species,  A. fumigatus:    
     Nucleic acid diagnostics assays were designed for  Aspergillus  spp using the primers SEQ ID NO 414 through to SEQ ID NO 418 and oligonucleotide probes SEQ ID 419 through to SEQ ID NO 448. One example of the assays developed is a real-time PCR TaqMan assay for  A. fumigatus  including primer sequences SEQ ID NO 418 and SEQ ID NO 415 and DNA oligonucleotide probe SEQ ID NO 419. This assay was configured on the LightCycler real-time PCR machine and performed using the conditions and reagents described in Table 4. The limit of detection (LOD) or sensitivity of the assay was determined using 10-serial dilutions (10 6 -1 cell equivalent) of genomic DNA from  A. fumigatus  strain number 5062.  FIG. 5  shows the LOD for the  A. fumigatus  assay as 1 genome equivalent. The specificity of the  A. fumigatus  assay was confirmed by testing the  A. fumigatus  assay for inclusivity using 20 strains of  A. fumigatus . All 20 strains were detected in the assay ( FIG. 6 ). The  A. fumigatus  assay was checked for cross-reactivity against a panel including 20 species of  Candida,  24 species dermatophytes, 8 species of  Aspergillus  spp. 15 bacterial species and human DNA. There was no cross-reaction of these strains/species or human DNA (Table 5) in the  A. fumigatus  assay.  FIG. 7  shows an example of cross-reactivity study performed using a panel of  Aspergillus  species DNA. 
     In so far as any sequence disclosed herein differs from its counterpart in the attached sequence listing in PatentIn3.3 software, the sequences within this body of text are to be considered as the correct version. 
     The words “comprises/comprising” and the words “having/including” when used herein with reference to the present invention are used to specify the presence of stated features, integers, steps or components but does not preclude the presence or addition of one or more other features, integers, steps, components or groups thereof. 
     It is appreciated that certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features of the invention which are, for brevity, described in the context of a single embodiment, may also be provided separately or in any suitable sub-combination. 
     SEQ IDs 
     Sites of probes, oligonucleotides etc. are shown in bold and underlined. 
     N or x=any nucleotide; w=a/t, m=a/c, r=a/g, k=g/t, s=c/g, y=c/t, h=a/t/c, v=a/g/c, d=a/g/t, b=g/t/c. 
     In some cases, specific degeneracy options are indicated in parenthesis: e.g.: (a/g) is either A or G. 
     
       
         
               
               
               
               
             
               
               
             
           
               
                 SEQ ID NO 1 
                 TAACATCGTAGGCTAATC 
                 CASP 
                   
               
               
                   
               
               
                 SEQ ID NO 2 
                 TCTGGGTATCTGATGTTCT 
                 Can2R-n15 
               
               
                   
               
               
                 SEQ ID NO 3 
                 TCTGGGTATCTGAT(a/g)GTTCT 
                 Can2R-d15: 
               
               
                   
               
               
                 SEQ ID NO 4 
                 TCTGGGTATCTGATAGTTCT 
                 Can2R-A15: 
               
               
                   
               
               
                 SEQ ID NO 5 
                 TCTGGGTATCTGATGGTTCT 
                 Can2R-G15: 
               
               
                   
               
               
                 SEQ ID NO 6 
                 TAACATCGTAGGCTAATC 
                   C. albicans  antisense probe 
               
               
                   
               
               
                 SEQ ID NO 7 
                 GATTAGCCTACGATGTTA 
                   C. albicans  specific probe 
               
               
                   
               
               
                 RPS7 primer (i) 
                   
                   
               
               
                 SEQ ID NO 8 
                 ATGGnTAGAGGnCCAAAGAAnCA 
                   
               
               
                   
               
               
                 SEQ ID NO 9 
                 ATGG(c/g)TAGAGG(a/t)CCAAAGAA(g/a)CA 
                   
               
               
                   
               
               
                 SEQ ID NO 10 
                 ATGGCTAGAGGnCCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 11 
                 ATGGCTAGAGGnCCAAAGAAACA 
                   
               
               
                   
               
               
                 SEQ ID NO 12 
                 ATGGGTAGAGGnCCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 13 
                 ATGGGTAGAGGnCCAAAGAAACA 
                   
               
               
                   
               
               
                 SEQ ID NO 14 
                 ATGGCTAGAGGACCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 15 
                 ATGGCTAGAGGACCAAAGAAACA 
                   
               
               
                   
               
               
                 SEQ ID NO 16 
                 ATGGCTAGAGGTCCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 17 
                 ATGGCTAGAGGTCCAAAGAAACA 
                   
               
               
                   
               
               
                 SEQ ID NO 18 
                 ATGGGTAGAGGACCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 19 
                 ATGGGTAGAGGACCAAAGAAACA 
                   
               
               
                   
               
               
                 SEQ ID NO 20 
                 ATGGGTAGAGGTCCAAAGAAGCA 
                   
               
               
                   
               
               
                 SEQ ID NO 21 
                 ATGGGTAGAGGTCCAAAGAAACA 
                   
               
               
                   
               
               
                 RPS7 primer (ii) 
                   
                   
               
               
                 SEQ ID NO 22 
                 GCnCCAAGACCATCnGCTGGTCCnCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 23 
                 GC(c/t/a)CCAAGACCATC(t/c)GCTGGTCC(a/t)CACA 
                   
               
               
                   
               
               
                 SEQ ID NO 24 
                 GCCCCAAGACCATCTGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 25 
                 GCTCCAAGACCATCTGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 26 
                 GCACCAAGACCATCTGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 27 
                 GCCCCAAGACCATCCGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 28 
                 GCTCCAAGACCATCCGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 29 
                 GCACCAAGACCATCCGCTGGTCCACACA 
                   
               
               
                   
               
               
                 SEQ ID NO 30 
                 GCCCCAAGACCATCTGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 31 
                 GCTCCAAGACCATCTGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 32 
                 GCACCAAGACCATCTGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 33 
                 GCCCCAAGACCATCCGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 34 
                 GCTCCAAGACCATCCGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 SEQ ID NO 35 
                 GCACCAAGACCATCCGCTGGTCCTCACA 
                   
               
               
                   
               
               
                 RPS7 primer (iii) 
                   
                   
               
               
                 SEQ ID NO 36 
                 CCAGCTGGTTTCATGGATGTnATCA 
                   
               
               
                   
               
               
                 SEQ ID NO 37 
                 CCCAGCTGGTTTCATGGATGT(c/t)ATCA 
                   
               
               
                   
               
               
                 SEQ ID NO 38 
                 CCCAGCTGGTTTCATGGATGTCATCA 
                   
               
               
                   
               
               
                 SEQ ID NO 39 
                 CCCAGCTGGTTTCATGGATGTTATCA 
                   
               
               
                   
               
               
                 SEQ ID NO 40 
                 
                   AGCTGGTTTCATGGATGT 
                 
                 Can1F genus specific primer 
               
               
                   
               
               
                 RPS7 primer (iv) 
                   
                   
               
               
                 SEQ ID NO 41 
                 AGAACnATCAGATACCCAGAnCCA 
                   
               
               
                   
               
               
                 SEQ ID NO 42 
                 AGAAC(c/t)ATCAGATACCCAGA(c/t)CCA 
                   
               
               
                   
               
               
                 SEQ ID NO 43 
                 AGAACTATCAGATACCCAGACCCA 
                   
               
               
                   
               
               
                 SEQ ID NO 44 
                 AGAACTATCAGATACCCAGATCCA 
                   
               
               
                   
               
               
                 SEQ ID NO 45 
                 AGAACCATCAGATACCCAGACCCA 
                   
               
               
                   
               
               
                 SEQ ID NO 46 
                 AGAACnATCAGATACCCAGA 
                   
               
               
                   
               
               
                 SEQ ID NO 47 
                 AGAAC(c/t)ATCAGATACCCAGA 
                 degen.3′-5′genus spec. primer 
               
               
                   
               
               
                 SEQ ID NO 48 
                 AGAACCATCAGATACCCAGA 
                   
               
               
                   
               
               
                 SEQ ID NO 49 
                 AGAACTATCAGATACCCAGA 
                   
               
               
                   
               
             
          
           
               
                 SEQ ID NO: 50:  S. cerevisiae   
                   
               
               
                   AGCTGGTTTC ATGGATGT CT AGATGCCACC AATGAAAACT TCAGATTGGT CTACGATGTC AAGGGTAGAT 
               
               
                   
               
               
                 TCGCTGTCCA CCGTATCACC GATGAAGAAG CTTCTTACAA GTTGGGTAAG GTCAAGAAGG TTCAATTAGG 
               
               
                   
               
               
                 TAAGAAGGGT GTTCCATACG TTGTTACCCA CGATGGT AGA   ACTATCAGAT   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 51: 
               
               
                   AGCUGGUUUC AUGGAUGU CU AGAUGCCACC AAUGAAAACU UCAGAUUGGU CUACGAUGUC AAGGGUAGAU 
               
               
                   
               
               
                 UCGCUGUCCA CCGUAUCACC GAUGAAGAAG CUUCUUACAA GUUGGGUAAG GUCAAGAAGG UUCAAUUAGG 
               
               
                   
               
               
                 UAAGAAGGGU GUUCCAUACG UUGUUACCCA CGAUGGU AGA   ACUAUCAGAU   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 52;  C. glabrata   
               
               
                   AGCTGGTTTC ATGGATGT TT GGAAGCTACC AACGAAAACT TCAGATTGGT CTACGACGTC AAGGGTAGAT 
               
               
                   
               
               
                 TCGCTGTCCA CCGTATCACT GACGAAGAAG CTTCCTACAA GTTGGGTAAG GTCAAGAAGG TCCAATTGGG 
               
               
                   
               
               
                 TAAGAAGGGT GTTCCATACG TTGTCACTGA CGATGGT AGA   ACTATCAGAT   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 53;  C. glabrata   
               
               
                   AGCUGGUUUC AUGGAUGU UU GGAAGCUACC AACGAAAACU UCAGAUUGGU CUACGACGUC AAGGGUAGAU 
               
               
                   
               
               
                 UCGCUGUCCA CCGUAUCACU GACGAAGAAG CUUCCUACAA GUUGGGUAAG GUCAAGAAGG UCCAAUUGGG 
               
               
                   
               
               
                 UAAGAAGGGU GUUCCAUACG UUGUCACUGA CGAUGGU AGA   ACUAUCAGAU   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 54;  E. gossypii   
               
               
                   AGCTGGTTTC ATGGATGT CT AGAGGCTACC AACGAGAACT TCAGATTGGT ATACGATGTC AAGGGCAGAT 
               
               
                   
               
               
                 TTGCTGTCCA CCGTATCACC GATGAGGAGG CTACTTACAA GTTGGGTAAG GTTAAGCGCG TTCAGCTAGG 
               
               
                   
               
               
                 TAAGAAGGGT GTCCCATACG TGGTCACTCA CGACGGC AGA   ACCATCAGAT   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 55;  E. gossypii   
               
               
                   AGCUGGUUUC AUGGAUGU CU AGAGGCUACC AACGAGAACU UCAGAUUGGU AUACGAUGUC AAGGGCAGAU 
               
               
                   
               
               
                 UUGCUGUCCA CCGUAUCACC GAUGAGGAGG CUACUUACAA GUUGGGUAAG GUUAAGCGCG UUCAGCUAGG 
               
               
                   
               
               
                 UAAGAAGGGU GUCCCAUACG UGGUCACUCA CGACGGC AGA   ACCAUCAGAU   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 56;  K. lactis   
               
               
                   AGCTGGTTTC ATGGATGT TT GGAAGCTACC AACGAAAACT TCAGATTGGT CTACGATGTT AAGGGTAGAT 
               
               
                   
               
               
                 TCGCTGTCCA CCGTATCACT GATGAAGAAG CTTCCTACAA GTTGGCTAAG GTCAAGAAGG TTCAACTAGG 
               
               
                   
               
               
                 TAAGAAGGGT ATTCCATACG TCGTTACCCA CGACGGT AGA   ACCATCAGAT   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 57;  K. lactis   
               
               
                   AGCUGGUUUC AUGGAUGU UU GGAAGCUACC AACGAAAACU UCAGAUUGGU CUACGAUGUU AAGGGUAGAU 
               
               
                   
               
               
                 UCGCUGUCCA CCGUAUCACU GAUGAAGAAG CUUCCUACAA GUUGGCUAAG GUCAAGAAGG UUCAACUAGG 
               
               
                   
               
               
                 UAAGAAGGGU AUUCCAUACG UCGUUACCCA CGACGGU AGA   ACCAUCAGAU   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 58;  C. albicans  RPS7 
               
               
                   AGCTGGTTTC ATGGATGT CT GGAAGCTACC AACGAACATT TCAGATTAGC CTACGATGTT AAAGGTAAAT 
               
               
                   
               
               
                 TCGCCGTTCA CAGAATTTCT GCTGAAGAAG CTGTCTACAA ATTGGGTAAA GTCAAGAAAG TCCAATTAGG 
               
               
                   
               
               
                 TAAGAAAGGT GTTCCATACG TTGTTACCCA CGACGGT AGA   ACTATCAGAT   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 59;  C. albicans  RPS7 
               
               
                   AGCUGGUUUC AUGGAUGU CU GGAAGCUACC AACGAACAUU UCAGAUUAGC CUACGAUGUU AAAGGUAAAU 
               
               
                   
               
               
                 UCGCCGUUCA CAGAAUUUCU GCUGAAGAAG CUGUCUACAA AUUGGGUAAA GUCAAGAAAG UCCAAUUAGG 
               
               
                   
               
               
                 UAAGAAAGGU GUUCCAUACG UUGUUACCCA CGACGGU AGA   ACUAUCAGAU   ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 60;  D. hansenii   
               
               
                   AGCTGGTTTC ATGGATGT CT AGAAGCTACC AACGAACACT TCAGATTAAT CTATGATGTC AAGGGTAGAT 
               
               
                   
               
               
                 TCACTGTCCA CAGAATCACT GCTGAAGAAG CTTCTTACAA GTTAGCTAAG GTCAAGAAGG TCCAATTAGG 
               
               
                   
               
               
                 TAAGAGAGGT ATTCCATACG TTGTCACCCA CGACGGT AGA ACTATCAGAT ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 61;  D. hansenii   
               
               
                   AGCUGGUUUC AUGGAUGU CU AGAAGCUACC AACGAACACU UCAGAUUAAU CUAUGAUGUC AAGGGUAGAU 
               
               
                   
               
               
                 UCACUGUCCA CAGAAUCACU GCUGAAGAAG CUUCUUACAA GUUAGCUAAG GUCAAGAAGG UCCAAUUAGG 
               
               
                   
               
               
                 UAAGAGAGGU AUUCCAUACG UUGUCACCCA CGACGGU AGA ACUAUCAGAU ACCCAGA   
               
               
                   
               
               
                 SEQ ID NO: 62;  C. albicans   
               
               
                 ACCTACCCAGCTGGTTTCATGGATGTCATCACCTTGGAAGCTACCAACGAACATTTCA   GA    300 
               
               
                   
               
               
                     TTAGCCTACGATGTTA   AAGGTAAATTCGCCGTTCACAGAATTTCTGCTGAAGAAGCTGTC 360 
               
               
                   
               
               
                 TACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTT 420 
               
               
                   
               
               
                 ACCCACGACGGTAGAACTATCAGATACCCAGATCCATTGATCAGAGCTAACGATACCGTT 480 
               
               
                   
               
               
                 SEQ ID NO: 63;  C. albicans   
               
               
                 ACCUACCCAGCUGGUUUCAUGGAUGUCAUCACCUUGGAAGCUACCAACGAACAUUUCA   GA    300 
               
               
                   
               
               
                     UUAGCCUACGAUGUUA   AAGGUAAAUUCGCCGUUCACAGAAUUUCUGCUGAAGAAGCUGUC 360 
               
               
                   
               
               
                 UACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUU 420 
               
               
                   
               
               
                 ACCCACGACGGUAGAACUAUCAGAUACCCAGAUCCAUUGAUCAGAGCUAACGAUACCGUU 480 
               
               
                   
               
               
                 SEQ ID NO: 64;  C. glabrata   
               
               
                 ACCTACCCAGCTGGTTTCATGGATGTTATCACCTTGGAAGCTACCAACGAAAACTTCAGA 300 
               
               
                   
               
               
                 TTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTGACGAAGAAGCTTCC 360 
               
               
                   
               
               
                 TACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTC 420 
               
               
                   
               
               
                 ACTGACGATGGTAGAACTATCAGATACCCAGACCCAAACATCAAGGTCAATGACACCGTC 480 
               
               
                   
               
               
                 SEQ ID NO: 65;  C. glabrata   
               
               
                 ACCUACCCAGCUGGUUUCAUGGAUGUUAUCACCUUGGAAGCUACCAACGAAAACUUCAGA 300 
               
               
                   
               
               
                 UUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUGACGAAGAAGCUUCC 360 
               
               
                   
               
               
                 UACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUC 420 
               
               
                   
               
               
                 ACUGACGAUGGUAGAACUAUCAGAUACCCAGACCCAAACAUCAAGGUCAAUGACACCGUC 480 
               
               
                   
               
               
                 SEQ ID NO: 66;  C. tropicalis   
               
               
                 -----------------------------------GGAAGCTACCAACGAACACTTCA GA   25 
               
               
                   
               
               
                   TTGATTTACGATGTT AAAGGTAAATTCGCTGTTCACAGAATTTCTGCTGAAGAAGCTTCT  85 
               
               
                   
               
               
                 TACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTC 145 
               
               
                   
               
               
                 ACCCACGATGGT AGAACCATCAGATACCCAGA ---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 67;  C. Tropicalis   
               
               
                 -----------------------------------GGAAGCUACCAACGAACACUUCAGA  25 
               
               
                   
               
               
                 UUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUGCUGAAGAAGCUUCU  85 
               
               
                   
               
               
                 UACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUC 145 
               
               
                   
               
               
                 ACCCACGAUGGUAGAACCAUCAGAUACCCAGA---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 68;  C. parapsilosis   
               
               
                 -----------------------------------GGAAGCCACCAATGAAAACTTTA GA   25 
               
               
                   
               
               
                   TTGATTTACGATGTC AAAGGTAGATTTGCTGTCCACAGAATCTCAGCTGAAGAAGCCACT  85 
               
               
                   
               
               
                 TACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTC 145 
               
               
                   
               
               
                 ACCCACGATGGT AGAACCATCAGATACCCAGA ---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 69;  C. parapsilosis   
               
               
                 -----------------------------------GGAAGCCACCAAUGAAAACUUUAGA  25 
               
               
                   
               
               
                 UUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAGCUGAAGAAGCCACU  85 
               
               
                   
               
               
                 UACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUC 145 
               
               
                   
               
               
                 ACCCACGAUGGUAGAACCAUCAGAUACCCAGA---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 70;  C. dubliniensis   
               
               
                 -----------------------------------GGAAGCTACCAACGAAAACTTCA GA   25 
               
               
                   
               
               
                   TTGGTCTACGACGTCA AGGGTAGATTCGCTGTCCACCGTATCACTGACGAAGAAGCTTCC  85 
               
               
                   
               
               
                 TACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTC 145 
               
               
                   
               
               
                 ACTGACGATGGT AGAACYATCAGATACCCAGA ---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 71;  C. dubliniensis   
               
               
                 -----------------------------------GGAAGCUACCAACGAAAACUUCAGA  25 
               
               
                   
               
               
                 UUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUGACGAAGAAGCUUCC  85 
               
               
                   
               
               
                 UACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUC 145 
               
               
                   
               
               
                 ACUGACGAUGGUAGAACYAUCAGAUACCCAGA---------------------------- 177 
               
               
                   
               
               
                 SEQ ID NO: 72; &gt; C. albicans 369 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 73; &gt; C. albicans 369 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 74; &gt; C. albicans 178 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 75; &gt; C. albicans 178 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 76; &gt; C. albicans 180 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 77; &gt; C. albicans 180 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 78; &gt; C. albicans 320 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 79; &gt; C. albicans 320 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 80; &gt; C. albicans 765 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 81; &gt; C. albicans 765 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 82; &gt; C. albicans 16733 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 83; &gt; C. albicans 16733 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 84; &gt; C. albicans 15640 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 85; &gt; C. albicans 15640 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 86; &gt; C. albicans 9559 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 87; &gt; C. albicans 9559 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 88; &gt; C. albicans 4154 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 89; &gt; C. albicans 4154 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 90; &gt; C. albicans 2700 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 91; &gt; C. albicans 2700 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 92; &gt; C. albicans 562 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 93; &gt; C. albicans 562 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 94; &gt; C. albicans 3822 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 95; &gt; C. albicans 3822 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 96; &gt; C. albicans 3156 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 97; &gt; C. albicans 3156 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 98; &gt; C. albicans 3345 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 99; &gt; C. albicans 3345 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 100; &gt; C. albicans 3328 
               
               
                 CATCACCTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 101; &gt; C. albicans 3328 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 102; &gt; C. glabrata 90876 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 103; &gt; C. glabrata 90876 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 104; &gt; C. glabrata 4692 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 105; &gt; C. glabrata 4692 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 106; &gt; C. glabrata 205444 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 107; &gt; C. glabrata 205444 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 108; &gt; C. glabrata 10269 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 109; &gt; C. glabrata 10269 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 110; &gt; C. glabrata 9556 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 111; &gt; C. glabrata 9556 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 112; &gt; C. glabrata 5563 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 113; &gt; C. glabrata 5563 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 114; &gt; C. glabrata 3959 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 115; &gt; C. glabrata 3959 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 116; &gt; C. glabrata 138 
               
               
                 CATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 117; &gt; C. glabrata 138 
               
               
                 CAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 118; &gt; C. glabrata 3605 
               
               
                 TATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 119; &gt; C. glabrata 3605 
               
               
                 UAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 120; &gt; C. glabrata 3897 
               
               
                 TATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 121; &gt; C. glabrata 3897 
               
               
                 UAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 122; &gt; C. glabrata 8018 
               
               
                 TATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 123; &gt; C. glabrata 8018 
               
               
                 UAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 124; &gt; C. glabrata 3863 
               
               
                 TATCACCTTGGAAGCTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTG 
               
               
                   
               
               
                 ACGAAGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTCACTGAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 125; &gt; C. glabrata 3863 
               
               
                 UAUCACCUUGGAAGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUG 
               
               
                   
               
               
                 ACGAAGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUCACUGAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 126; &gt; C. parapsilosis 3902 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 127; &gt; C. parapsilosis 3902 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 128; &gt; C. parapsilosis 604 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 129; &gt; C. parapsilosis 604 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 130; &gt; C. parapsilosis 2194 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 131; &gt; C. parapsilosis 2194 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 132; &gt; C. parapsilosis 2196 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 133; &gt; C. parapsilosis 2196 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 134; &gt; C. parapsilosis 1001 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 135; &gt; C. parapsilosis 1001 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 136; &gt; C. parapsilosis 1716 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 137; &gt; C. parapsilosis 1716 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 138; &gt; C. parapsilosis 9557 
               
               
                 CATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 139; &gt; C. parapsilosis 9557 
               
               
                 CAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 140; &gt; C. krusei 5579 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 141; &gt; C. krusei 5579 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 142; &gt; C. krusei 9560 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 143; &gt; C. krusei 9560 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 144; &gt; C. krusei 6055 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 145; &gt; C. krusei 6055 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 146; &gt; C. krusei 17518 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 147; &gt; C. krusei 17518 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 148; &gt; C. krusei 573 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 149; &gt; C. krusei 573 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 150; &gt; C. krusei 3165 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 151; &gt; C. krusei 3165 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 152; &gt; C. krusei 3922 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 153; &gt; C. krusei 3922 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 154; &gt; C. krusei 3847 
               
               
                 CATCACTTTAGATGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 155; &gt; C. krusei 3847 
               
               
                 CAUCACUUUAGAUGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 156; &gt; C. tropicalis 3895 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 157; &gt; C. tropicalis 3895 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 158; &gt; C. tropicalis 94 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 159; &gt; C. tropicalis 94 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 160; &gt; C. tropicalis 4225 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 161; &gt; C. tropicalis 4225 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUGAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 162; &gt; C. tropicalis 5557 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 163; &gt; C. tropicalis 5557 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 164; &gt; C. tropicalis 15902 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 165; &gt; C. tropicalis 15902 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 166; &gt; C. tropicalis 4139 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 167; &gt; C. tropicalis 4139 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 168; &gt; C. tropicalis 3873 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 169; &gt; C. tropicalis 3873 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 170; &gt; C. tropicalis 3870 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 171; &gt; C. tropicalis 3870 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 172; &gt; C. tropicalis 8157 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 173; &gt; C. tropicalis 8157 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 174; &gt; C. tropicalis 2311 
               
               
                 CATCACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 175; &gt; C. tropicalis 2311 
               
               
                 CAUCACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ ID NO: 176;  Saccharomyces cerevisiae   
               
               
                   Saccharomyces cerevisiae  probe 1 
               
               
                 GATTGGTCTACGATGTCA 
               
               
                   
               
               
                 SEQ ID NO 177;  Saccharomyces cerevisiae   
               
               
                   Saccharomyces cerevisiae  probe 2 
               
               
                 TGACATCGTAGACCAATC 
               
               
                   
               
               
                 SEQ ID NO: 178;  Eremothecium gossypii   
               
               
                   Eremothecium gossypii  probe 1 
               
               
                 GATTGGTATACGATGTCA 
               
               
                   
               
               
                 SEQ ID NO: 179;  Eremothecium gossypii   
               
               
                   Eremothecium gossypii  probe 2 
               
               
                 TGACATCGTATACCAATC 
               
               
                   
               
               
                 SEQ ID NO 180;  Kluyveromyces lactis   
               
               
                   Kluyveromyces lactis  probe 1 
               
               
                 GATTGGTCTACGATGTTA 
               
               
                   
               
               
                 SEQ ID NO: 181;  Kluyveromyces lactis   
               
               
                   Kluyveromyces lactis  probe 2 
               
               
                 TAACATCGTAGACCAATC 
               
               
                   
               
               
                 SEQ ID NO 182;  C. dubliniensis  and  Candida glabrata   
               
               
                   C. dubliniensis  and  Candida glabrata  probe 1 
               
               
                 GATTGGTCTACGACGTCA 
               
               
                   
               
               
                 SEQ ID NO 183;  C. dubliniensis  and  Candida glabrata   
               
               
                   C. dubliniensis  and  Candida glabrata  probe 2 
               
               
                 TGACGTCGTAGACCAATC 
               
               
                   
               
               
                 SEQ ID NO 184;  Debaryomyces hansenii   
               
               
                   Debaryomyces hansenii  probe 1 
               
               
                 GATTGATCTATGACGTCA 
               
               
                   
               
               
                 SEQ ID NO: 185;  Debaryomyces hansenii   
               
               
                   Debaryomyces hansenii  probe 2 
               
               
                 TGACGTCATAGATCAATC 
               
               
                   
               
               
                 SEQ ID NO 186;  C. tropicalis   
               
               
                   C. tropicalis  probe 1 
               
               
                 GATTGATTTACGATGTTA 
               
               
                   
               
               
                 SEQ ID NO 187;  C. tropicalis   
               
               
                   C. tropicalis  probe 2 
               
               
                 TAACATCGTAAATCAATC 
               
               
                   
               
               
                 SEQ ID NO 188;  C. parapsilosis   
               
               
                   C. parapsilosis  probe 1 
               
               
                 GATTGATTTACGATGTCA 
               
               
                   
               
               
                 SEQ ID NO 189;  C. parapsilosis  probe 2 
               
               
                 
                   C. parapsilosis 
                 
               
               
                 TGACATCGTAAATCAATC 
               
               
                   
               
               
                 SEQ ID NO 190;  Saccharomyces cerevisiae   
               
               
                   ATGGCTAGAG GACCAAAGAA GCA TCTAAAA AGATTAGCAG CTCCACACCA CTGGTTATTG  60 
               
               
                   
               
               
                 GACAAGTTGT CCGGTTGTTA C GCCCCAAGA CCATCTGCTG GTCCACA CAA ATTGCGTGAA 120 
               
               
                   
               
               
                 TCCTTGCCAT TGATTGTCTT TCTAAGAAAC AGATTAAAGT ATGCTTTGAA CGGCCGTGAA 180 
               
               
                   
               
               
                 GTCAAGGCTA TCTTGATGCA ACGTCACGTT AAAGTGGACG GTAAGGTTAG AACCGACACT 240 
               
               
                   
               
               
                 ACCTA CCC                                  CATC AC TCTAGATG CCACCAATGA AAACTTCA GA  300 
               
               
                   
               
               
                   TTGGTCTACG ATGTCA AGGG TAGATTCGCT GTCCACCGTA TCACCGATGA AGAAGCTTCT 360 
               
               
                   
               
               
                 TACAAGTTGG GTAAGGTCAA GAAGGTTCAA TTAGGTAAGA AGGTGTTCC ATACGTTGTT 420 
               
               
                   
               
               
                 ACCCACGATG GT                                CCCA AACA TCAAGGTCAA TGACACTGTT 480 
               
               
                   
               
               
                 AAGATCGACT TGGCCTCTGG TAAGATTACT GATTTCATCA AGTTCGATGC CGGTAAGTTG 540 
               
               
                   
               
               
                 GTTTACGTTA CTGGTGGTCG TAACTTGGGT CGTATCGGTA CTATCGTTCA CAAGGAAAGA 600 
               
               
                   
               
               
                 CACGATGGTG GTTTCGATTT AGTTCACATC AAGGACTCCT TGGACAACAC TTTCGTCACT 660 
               
               
                   
               
               
                 AGATTGAACA ATGTCTTCGT CATCGGTGAA CAAGGTAAGC CTTACATTTC TTTGCCAGGT 720 
               
               
                   
               
               
                 AAGGGTAAGG GTATCAAGTT GTCTATTGCT GAAGAACGTG ACAGAAGAAG AGCTCAACAA 780 
               
               
                   
               
               
                 TTATAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 191; RNA;  Saccharomyces cerevisiae   
               
               
                   AUGGCUAGAG GACCAAAGAA GCA UCUAAAA AGAUUAGCAG CUCCACACCA CUGGUUAUUG  60 
               
               
                   
               
               
                 GACAAGUUGU CCGGUUGUUA C GCCCCAAGA CCAUCUGCUG GUCCACA CAA AUUGCGUGAA 120 
               
               
                   
               
               
                 UCCUUGCCAU UGAUUGUCUU UCUAAGAAAC AGAUUAAAGU AUGCUUUGAA CGGCCGUGAA 180 
               
               
                   
               
               
                 GUCAAGGCUA UCUUGAUGCA ACGUCACGUU AAAGUGGACG GUAAGGUUAG AACCGACACU 240 
               
               
                   
               
               
                 ACCUA CCC                                  CAUC AC UCUAGAUG CCACCAAUGA AAACUUCA GA  300 
               
               
                   
               
               
                   UUGGUCUACG AUGUCA AGGG UAGAUUCGCU GUCCACCGUA UCACCGAUGA AGAAGCUUCU 360 
               
               
                   
               
               
                 UACAAGUUGG GUAAGGUCAA GAAGGUUCAA UUAGGUAAGA AGGGUGUUCC AUACGUUGUU 420 
               
               
                   
               
               
                 ACCCACGAUG GU                                CCCA AACA UCAAGGUCAA UGACACUGUU 480 
               
               
                   
               
               
                 AAGAUCGACU UGGCCUCUGG UAAGAUUACU GAUUUCAUCA AGUUCGAUGC CGGUAAGUUG 540 
               
               
                   
               
               
                 GUUUACGUUA CUGGUGGUCG UAACUUGGGU CGUAUCGGUA CUAUCGUUCA CAAGGAAAGA 600 
               
               
                   
               
               
                 CACGAUGGUG GUUUCGAUUU AGUUCACAUC AAGGACUCCU UGGACAACAC UUUCGUCACU 660 
               
               
                   
               
               
                 AGAUUGAACA AUGUCUUCGU CAUCGGUGAA CAAGGUAAGC CUUACAUUUC UUUGCCAGGU 720 
               
               
                   
               
               
                 AAGGGUAAGG GUAUCAAGUU GUCUAUUGCU GAAGAACGUG ACAGAAGAAG AGCUCAACAA 780 
               
               
                   
               
               
                 UUAUAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 192;  Candida glabrata   
               
               
                   ATGGCTAGAG GACCAAAGAA GCA TCTAAAG AGATTAGCAG CTCCACACCA CTGGTTGTTG  60 
               
               
                   
               
               
                 GACAAGTTGT CCGGCTGTTA C GCCCCAAGA CCATCCGCTG GTCCACA CAA GTTGCGTGAA 120 
               
               
                   
               
               
                 TCCCTACCAT TGATCGTTTT CTTGAGAAAC AGATTAAAGT ACGCTTTGAA CGGTCGTGAA 180 
               
               
                   
               
               
                 GTTAAGGCTA TCATGATGCA ACGTCATGTT AAGGTTGACG GTAAGGTCAG AACTGACGCT 240 
               
               
                   
               
               
                 ACCTA CCC                       TATC AC CTTGGAAG CTACCAACGA AAACTTCA GA  300 
               
               
                   
               
               
                   TTGGTCTACG ACGTCA AGGG TAGATTCGCT GTCCACCGTA TCACTGACGA AGAAGCTTCC 360 
               
               
                   
               
               
                 TACAAGTTGG GTAAGGTCAA GAAGGTCCAA TTGGGTAAGA AGGGTGTTCC ATACGTTGTC 420 
               
               
                   
               
               
                 ACTGACGATG GT                                CCCA AACA TCAAGGTCAA TGACACCGTC 480 
               
               
                   
               
               
                 AAGGTCGACT TGGCTTCCGG TAAGATCACT GACTACATCA AGTTCGACAT TGGTAAGTTG 540 
               
               
                   
               
               
                 GTCTACATCA CCGGTGGTCG TAACTTGGGT CGTATCGGTA CCATCGTTCA CAAGGAAAGA 600 
               
               
                   
               
               
                 CACGATGGTG GTTTCGACTT GGTTCACGTC AAGGACTCCT TGGACAACAC TTTCGTCACC 660 
               
               
                   
               
               
                 AGATTGAACA ACGTTTTCGT TATCGGTGAA CAAGGTAAGC CATACATCTC CTTGCCAAAG 720 
               
               
                   
               
               
                 GGTAAGGGTA TCAAGTTGAC CATTGCTGAA GAACGTGACA GAAGAAGAGC TCAACAAGGT 780 
               
               
                   
               
               
                 TTATAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 193; RNA;  Candida glabrata   
               
               
                   AUGGCUAGAG GACCAAAGAA GCA UCUAAAG AGAUUAGCAG CUCCACACCA CUGGUUGUUG  60 
               
               
                   
               
               
                 GACAAGUUGU CCGGCUGUUA C GCCCCAAGA CCAUCCGCUG GUCCACA CAA GUUGCGUGAA 120 
               
               
                   
               
               
                 UCCCUACCAU UGAUCGUUUU CUUGAGAAAC AGAUUAAAGU ACGCUUUGAA CGGUCGUGAA 180 
               
               
                   
               
               
                 GUUAAGGCUA UCAUGAUGCA ACGUCAUGUU AAGGUUGACG GUAAGGUCAG AACUGACGCU 240 
               
               
                   
               
               
                 ACCUA CCC                                  UAUC AC CUUGGAAG CUACCAACGA AAACUUCA GA  300 
               
               
                   
               
               
                   UUGGUCUACG ACGUCA AGGG UAGAUUCGCU GUCCACCGUA UCACUGACGA AGAAGCUUCC 360 
               
               
                   
               
               
                 UACAAGUUGG GUAAGGUCAA GAAGGUCCAA UUGGGUAAGA AGGGUGUUCC AUACGUUGUC 420 
               
               
                   
               
               
                 ACUGACGAUG GU                                CCCA AACA UCAAGGUCAA UGACACCGUC 480 
               
               
                   
               
               
                 AAGGUCGACU UGGCUUCCGG UAAGAUCACU GACUACAUCA AGUUCGACAU UGGUAAGUUG 540 
               
               
                   
               
               
                 GUCUACAUCA CCGGUGGUCG UAACUUGGGU CGUAUCGGUA CCAUCGUUCA CAAGGAAAGA 600 
               
               
                   
               
               
                 CACGAUGGUG GUUUCGACUU GGUUCACGUC AAGGACUCCU UGGACAACAC UUUCGUCACC 660 
               
               
                   
               
               
                 AGAUUGAACA ACGUUUUCGU UAUCGGUGAA CAAGGUAAGC CAUACAUCUC CUUGCCAAAG 720 
               
               
                   
               
               
                 GGUAAGGGUA UCAAGUUGAC CAUUGCUGAA GAACGUGACA GAAGAAGAGC UCAACAAGGU 780 
               
               
                   
               
               
                 UUAUAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 194;  Eremothecium gossypii   
               
               
                   ATGGCTAGAG GACCAAAGAA GCA CCTGAAG AGATTGGCAG CTCCACACCA CTGGTTGTTG  60 
               
               
                   
               
               
                 GACAAGCTAT CCGGCTGTTA C GCTCCAAGA CCATCCGCTG GTCCACA CAA GTTGCGCGAG 120 
               
               
                   
               
               
                 TCTTTGCCAT TGATCGTCTT CTTGAGAAAC AGATTAAAGT ATGCTTTGAA CGGTCGCGAG 180 
               
               
                   
               
               
                 GTCAAGGCCA TCCTAATGCA GCGTCATGTT AAGGTTGACG GTAAGGTCAG AACTGACACT 240 
               
               
                   
               
               
                 ACCTA CCC                                  CATC AC TCTAGAGG CTACCAACGA GAACTTCA GA  300 
               
               
                   
               
               
                   TTGGTATACG ATGTCA AGGG CAGATTTGCT GTCCACCGTA TCACCGATGA GGAGGCTACT 360 
               
               
                   
               
               
                 TACAAGTTGG GTAAGGTTAA GCGCGTTCAG CTAGGTAAGA AGGGTGTCCC ATACGTGGTC 420 
               
               
                   
               
               
                 ACTCACGACG GC                                 CCCA AACA TCAAGGTTAA CGACACCGTC 480 
               
               
                   
               
               
                 AAGGTTGACC TTGCTACTGG TAAGATTACC GACTTCATCA AGTTCGACAC TGGTAAGTTG 540 
               
               
                   
               
               
                 GTGTACGTCA CCGGTGGCCG TAACTTGGGC CGTATTGGTG TCATCACCCA CAGAGAGAGA 600 
               
               
                   
               
               
                 CACGAGGGTG GCTTTGACTT GGTTCACATC AAGGACTCCT TGGAGAACAC TTTCGTCACC 660 
               
               
                   
               
               
                 AGATTGAACA ACGTTTTCGT CATCGGTGAG CAAGGTAGAC CATGGATCTC CTTGCCAAGG 720 
               
               
                   
               
               
                 GGTAAGGGTA TTAAGTTGTC CATTGCTGAG GAGCGTGACC GTAGAAGAGC TCAACAAGGT 780 
               
               
                   
               
               
                 TTGTAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 195; RNA;  Eremothecium gossypii   
               
               
                   AUGGCUAGAG GACCAAAGAA GCA CCUGAAG AGAUUGGCAG CUCCACACCA CUGGUUGUUG  60 
               
               
                   
               
               
                 GACAAGCUAU CCGGCUGUUA C GCUCCAAGA CCAUCCGCUG GUCCACA CAA GUUGCGCGAG 120 
               
               
                   
               
               
                 UCUUUGCCAU UGAUCGUCUU CUUGAGAAAC AGAUUAAAGU AUGCUUUGAA CGGUCGCGAG 180 
               
               
                   
               
               
                 GUCAAGGCCA UCCUAAUGCA GCGUCAUGUU AAGGUUGACG GUAAGGUCAG AACUGACACU 240 
               
               
                   
               
               
                 ACCUA CCC                                  CAUC AC UCUAGAGG CUACCAACGA GAACUUCA GA  300 
               
               
                   
               
               
                   UUGGUAUACG AUGUCA AGGG CAGAUUUGCU GUCCACCGUA UCACCGAUGA GGAGGCUACU 360 
               
               
                   
               
               
                 UACAAGUUGG GUAAGGUUAA GCGCGUUCAG CUAGGUAAGA AGGGUGUCCC AUACGUGGUC 420 
               
               
                   
               
               
                 ACUCACGACG GC                                CCCA AACA UCAAGGUUAA CGACACCGUC 480 
               
               
                   
               
               
                 AAGGUUGACC UUGCUACUGG UAAGAUUACC GACUUCAUCA AGUUCGACAC UGGUAAGUUG 540 
               
               
                   
               
               
                 GUGUACGUCA CCGGUGGCCG UAACUUGGGC CGUAUUGGUG UCAUCACCCA CAGAGAGAGA 600 
               
               
                   
               
               
                 CACGAGGGUG GCUUUGACUU GGUUCACAUC AAGGACUCCU UGGAGAACAC UUUCGUCACC 660 
               
               
                   
               
               
                 AGAUUGAACA ACGUUUUCGU CAUCGGUGAG CAAGGUAGAC CAUGGAUCUC CUUGCCAAGG 720 
               
               
                   
               
               
                 GGUAAGGGUA UUAAGUUGUC CAUUGCUGAG GAGCGUGACC GUAGAAGAGC UCAACAAGGU 780 
               
               
                   
               
               
                 UUGUAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 196;  Kluyveromyces lactis   
               
               
                   ATGGCTAGAG GACCAAAGAA GCA TCTAAAG AGATTAGCAG CTCCACATCA TTGGATGTTG  60 
               
               
                   
               
               
                 GACAAGTTGT CCGGTTGTTA C GCACCAAGA CCATCTGCTG GTCCACA CAA GTTGCGTGAA 120 
               
               
                   
               
               
                 TCCTTGCCAT TGATCGTTTT CTTGAGAAAC AGATTAAAGT ATGCTTTGAA CGGTCGTGAA 180 
               
               
                   
               
               
                 GTCAAGGCCA TCTTGATGCA ACGTCATGTC AAGGTTGACG GTAAGGTCAG AACCGACACT 240 
               
               
                   
               
               
                 ACTTT CCC                                  TATC AC CTTGGAAG CTACCAACGA AAACTTCA GA  300 
               
               
                   
               
               
                   TTGGTCTACG ATGTTA AGGG TAGATTCGCT GTCCACCGTA TCACTGATGA AGAAGCTTCC 360 
               
               
                   
               
               
                 TACAAGTTGG CTAAGGTCAA GAAGGTTCAA CTAGGTAAGA AGGGTATTCC ATACGTCGTT 420 
               
               
                   
               
               
                 ACCCACGACG GT                                CCCA AACA TCAAGGTTAA CGACACCGTT 480 
               
               
                   
               
               
                 AAGGTTGATT TGGCTACTGG TACTATCACC GATTTCATCA AATTCGACAC TGGTAAGTTG 540 
               
               
                   
               
               
                 GTTTATGTTA CCGGTGGTCG TAACTTGGGT AGAGTTGGTA CCATCGTCCA CAGAGAAAGA 600 
               
               
                   
               
               
                 CACGAAGGTG GTTTCGATTT GGTTCACATC AAGGATTCTT TGGAAAACAC TTTCGTCACC 660 
               
               
                   
               
               
                 AGATTGAACA ACGTTTTCGT CATCGGTGAA CCAGGTAGAC CATGGATCTC CTTGCCAAAG 717 
               
               
                   
               
               
                 GGTAAGGGTA TCAAGTTGAC CATCTCTGAA GAACGTGACC GTAGAAGAGC TCAACATGGT 777 
               
               
                   
               
               
                 TTGTAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 197; RNA;  Kluyveromyces lactis   
               
               
                   AUGGCUAGAG GACCAAAGAA GCA UCUAAAG AGAUUAGCAG CUCCACAUCA UUGGAUGUUG  60 
               
               
                   
               
               
                 GACAAGUUGU CCGGUUGUUA C GCACCAAGA CCAUCUGCUG GUCCACA CAA GUUGCGUGAA 120 
               
               
                   
               
               
                 UCCUUGCCAU UGAUCGUUUU CUUGAGAAAC AGAUUAAAGU AUGCUUUGAA CGGUCGUGAA 180 
               
               
                   
               
               
                 GUCAAGGCCA UCUUGAUGCA ACGUCAUGUC AAGGUUGACG GUAAGGUCAG AACCGACACU 240 
               
               
                   
               
               
                 ACUUU CCC                                  UAUC AC CUUGGAAG CUACCAACGA AAACUUCA GA  300 
               
               
                   
               
               
                   UUGGUCUACG AUGUUA AGGG UAGAUUCGCU GUCCACCGUA UCACUGAUGA AGAAGCUUCC 360 
               
               
                   
               
               
                 UACAAGUUGG CUAAGGUCAA GAAGGUUCAA CUAGGUAAGA AGGGUAUUCC AUACGUCGUU 420 
               
               
                   
               
               
                 ACCCACGACG GU                                CCCA AACA UCAAGGUUAA CGACACCGUU 480 
               
               
                   
               
               
                 AAGGUUGAUU UGGCUACUGG UACUAUCACC GAUUUCAUCA AAUUCGACAC UGGUAAGUUG 540 
               
               
                   
               
               
                 GUUUAUGUUA CCGGUGGUCG UAACUUGGGU AGAGUUGGUA CCAUCGUCCA CAGAGAAAGA 600 
               
               
                   
               
               
                 CACGAAGGUG GUUUCGAUUU GGUUCACAUC AAGGAUUCUU UGGAAAACAC UUUCGUCACC 660 
               
               
                   
               
               
                 AGAUUGAACA ACGUUUUCGU CAUCGGUGAA CCAGGUAGAC CAUGGAUCUC CUUGCCAAAG 717 
               
               
                   
               
               
                 GGUAAGGGUA UCAAGUUGAC CAUCUCUGAA GAACGUGACC GUAGAAGAGC UCAACAUGGU 777 
               
               
                   
               
               
                 UUGUAA--- 786 
               
               
                   
               
               
                 SEQ ID NO 198;  Candida albicans   
               
               
                   ATGGGTAGAG GTCCAAAGAA ACA CTTGAAA AGATTAGCAG CTCCATCTCA CTGGATGTTG  60 
               
               
                   
               
               
                 GNCAAATTGT CCGGTACTTA T GCTCCAAGA CCATCTGCTG GTCCACA CAN ATTGAGAGAA 120 
               
               
                   
               
               
                 TCATTACCAT TGGNTGTCTT TTTAAGAAAC AGATTGNAGT ATGCTTTGTG CGGTAGAGAA 180 
               
               
                   
               
               
                 GTCAAAGCCA TCATGATGCA ACAACACGTT CAAGTTGTCG GTAAAGTCAG AACTGATACC 240 
               
               
                   
               
               
                 ACCTA CCC                                  CATC AC CTTGGAAG CTACCAACGA ACATTTCA GA  300 
               
               
                   
               
               
                   TTAGCCTACG ATGTTA AAGG TAAATTCGCC GTTCACAGAA TTTCTGCTGA AGAAGCTGTC 360 
               
               
                   
               
               
                 TACAAATTGG GTAAAGTCAA GAAAGTCCAA TTAGGTAAGA AAGGTGTTCC ATACGTTGTT 420 
               
               
                   
               
               
                 ACCCACGACG GT                                TCCA TTGA TCAGAGCTAA CGATACCGTT 480 
               
               
                   
               
               
                 AAAATCGATT TGGCTACCGG TAAGATCGRT AGTTTCATCA AATTCGACAC TGGTAGATTA 540 
               
               
                   
               
               
                 GTTATGGTTA CTGGTGGTAG AAATTTGGGT AGAGTTGGTG TTATTGTCCA CAGAGAAAAA 600 
               
               
                   
               
               
                 CTCGAAGGAG GTTTCGATTT GGTCCACATC AAAGATGCTT TGGAAAACAC TTTCGTTACC 660 
               
               
                   
               
               
                 AGATTGTCTA ACGTTTTTGT TATTGGTACT GAAGCCGGTA AACCATGGGT CTCATTACCA 720 
               
               
                   
               
               
                 AAGGGTAAAG GTATCAAATT GTCTATTTCT GAAGAAAGAG ACAGAAGAAN AGCTCAACAA 780 
               
               
                   
               
               
                 GGTTTGTAA--- 789 
               
               
                   
               
               
                 SEQ ID NO 199; RNA;  Candida albicans   
               
               
                   AUGGGUAGAG GUCCAAAGAA ACA CUUGAAA AGAUUAGCAG CUCCAUCUCA CUGGAUGUUG  60 
               
               
                   
               
               
                 GNCAAAUUGU CCGGUACUUA U GCUCCAAGA CCAUCUGCUG GUCCACA CAN AUUGAGAGAA 120 
               
               
                   
               
               
                 UCAUUACCAU UGGNUGUCUU UUUAAGAAAC AGAUUGNAGU AUGCUUUGUG CGGUAGAGAA 180 
               
               
                   
               
               
                 GUCAAAGCCA UCAUGAUGCA ACAACACGUU CAAGUUGUCG GUAAAGUCAG AACUGAUACC 240 
               
               
                   
               
               
                 ACCUA CCC                                  CAUC AC CUUGGAAG CUACCAACGA ACAUUUCA GA  300 
               
               
                   
               
               
                   UUAGCCUACG AUGUUA AAGG UAAAUUCGCC GUUCACAGAA UUUCUGCUGA AGAAGCUGUC 360 
               
               
                   
               
               
                 UACAAAUUGG GUAAAGUCAA GAAAGUCCAA UUAGGUAAGA AAGGUGUUCC AUACGUUGUU 420 
               
               
                   
               
               
                 ACCCACGACG GU                                UCCA UUGA UCAGAGCUAA CGAUACCGUU 480 
               
               
                   
               
               
                 AAAAUCGAUU UGGCUACCGG UAAGAUCGRU AGUUUCAUCA AAUUCGACAC UGGUAGAUUA 540 
               
               
                   
               
               
                 GUUAUGGUUA CUGGUGGUAG AAAUUUGGGU AGAGUUGGUG UUAUUGUCCA CAGAGAAAAA 600 
               
               
                   
               
               
                 CUCGAAGGAG GUUUCGAUUU GGUCCACAUC AAAGAUGCUU UGGAAAACAC UUUCGUUACC 660 
               
               
                   
               
               
                 AGAUUGUCUA ACGUUUUUGU UAUUGGUACU GAAGCCGGUA AACCAUGGGU CUCAUUACCA 720 
               
               
                   
               
               
                 AAGGGUAAAG GUAUCAAAUU GUCUAUUUCU GAAGAAAGAG ACAGAAGAAN AGCUCAACAA 780 
               
               
                   
               
               
                 GGUUUGUAA--- 789 
               
               
                   
               
               
                 SEQ ID NO 200;  Debaryomyces hansenii   
               
               
                   ATGGGTAGAG GTCCAAAGAA GCA CTTGAAG AGATTAGCAG CACCATCCCA CTGGATGTTG  60 
               
               
                   
               
               
                 GACAAATTGT CCGGTACTTA C GCACCAAGA CCATCTGCTG GTCCTCA CAA ATTGAGAGAA 120 
               
               
                   
               
               
                 TCTTTACCAT TGGTTATCTT CTTAAGAAAC AGACTTAAGT ATGCCTTAAA CGGTAGAGAA 180 
               
               
                   
               
               
                 GTCAAGGCCA TCTTGATGCA AGAACACGTC AAGGTTGATG GTAAAGTTAG AACCGATGCT 240 
               
               
                   
               
               
                 ACTTT CCC                                  CATC AC TTTAGAAG CTACCAACGA ACACTTCA GA  300 
               
               
                   
               
               
                   TTAATCTATG ATGTCA AGGG TAGATTCACT GTCCACAGAA TCACTGCTGA AGAAGCTTCT 360 
               
               
                   
               
               
                 TACAAGTTAG CTAAGGTCAA GAAGGTCCAA TTAGGTAAGA GAGGTATTCC ATACGTTGTC 420 
               
               
                   
               
               
                 ACCCACGACG GT                                TCCA TTGA TCAGAGCCAA CGATTCCGTT 480 
               
               
                   
               
               
                 AAGGTTGACT TAGCTACCGG TAAGATCACT GACTTTATCA GCTTTGACAC TGGTAGATTA 540 
               
               
                   
               
               
                 GTCATGGTTA CTGGTGGTCG TAACATGGGT AGAGTTGGTG TTATCACCCA CAGAGAAAAG 600 
               
               
                   
               
               
                 CACGAGGGTG GTTTCGATTT AGTCCACATC AAGGATTCTT TGGAAAACAC TTTCGTTACC 660 
               
               
                   
               
               
                 AGATTAACTA ACGTCTTCAT CGTCGGTACT GAAGCTGGTA AGCCACACAT TTCTTTACCA 720 
               
               
                   
               
               
                 AAGGGTAAGG GTATTAAGTT ATCCATCTCT GAAGAACGTG ACAGAAGAAG AAACCAACAA 780 
               
               
                   
               
               
                 CTTATCAACT AA 792 
               
               
                   
               
               
                 SEQ ID NO 201; RNA;  Debaryomyces hansenii   
               
               
                   AUGGGUAGAG GUCCAAAGAA GCA CUUGAAG AGAUUAGCAG CACCAUCCCA CUGGAUGUUG  60 
               
               
                   
               
               
                 GACAAAUUGU CCGGUACUUA C GCACCAAGA CCAUCUGCUG GUCCUCA CAA AUUGAGAGAA 120 
               
               
                   
               
               
                 UCUUUACCAU UGGUUAUCUU CUUAAGAAAC AGACUUAAGU AUGCCUUAAA CGGUAGAGAA 180 
               
               
                   
               
               
                 GUCAAGGCCA UCUUGAUGCA AGAACACGUC AAGGUUGAUG GUAAAGUUAG AACCGAUGCU 240 
               
               
                   
               
               
                 ACUUU CCC                                  CAUC AC UUUAGAAG CUACCAACGA ACACUUCA GA  300 
               
               
                   
               
               
                   UUAAUCUAUG AUGUCA AGGG UAGAUUCACU GUCCACAGAA UCACUGCUGA AGAAGCUUCU 360 
               
               
                   
               
               
                 UACAAGUUAG CUAAGGUCAA GAAGGUCCAA UUAGGUAAGA GAGGUAUUCC AUACGUUGUC 420 
               
               
                   
               
               
                 ACCCACGACG GU                                UCCA UUGA UCAGAGCCAA CGAUUCCGUU 480 
               
               
                   
               
               
                 AAGGUUGACU UAGCUACCGG UAAGAUCACU GACUUUAUCA GCUUUGACAC UGGUAGAUUA 540 
               
               
                   
               
               
                 GUCAUGGUUA CUGGUGGUCG UAACAUGGGU AGAGUUGGUG UUAUCACCCA CAGAGAAAAG 600 
               
               
                   
               
               
                 CACGAGGGUG GUUUCGAUUU AGUCCACAUC AAGGAUUCUU UGGAAAACAC UUUCGUUACC 660 
               
               
                   
               
               
                 AGAUUAACUA ACGUCUUCAU CGUCGGUACU GAAGCUGGUA AGCCACACAU UUCUUUACCA 720 
               
               
                   
               
               
                 AAGGGUAAGG GUAUUAAGUU AUCCAUCUCU GAAGAACGUG ACAGAAGAAG AAACCAACAA 780 
               
               
                   
               
               
                 CUUAUCAACU AA 792 
               
               
                   
               
               
                 SEQ ID NO 202; U37009.1  Candida albicans  SGY-243 
               
               
                 GAATTCGTTGCTTGAGCAAGAGGAAAAGCTTACTAAATTGATAAAGCAGGCAAATAGAAATAGTACTTGG 
               
               
                   
               
               
                 TTCAAATGGAATAAATAGTTTGTGTGTTGATTTCGCGAAAAAGAAATGTAAAGTAATACTGATTAGGGCT 
               
               
                   
               
               
                 ATAGCCCTAACTGGTTTCTCGCACTCTTTTCACTACCAATTACTAAAAAAAAAAAATTTGGTGAAAAAAA 
               
               
                   
               
               
                 AAAATTATCTACCACTCCCTATACCATCATCATCAACAATAAACCCACAATGGGTAGAGGTCCAAAGAAA 
               
               
                   
               
               
                 CACTTGAAAAGATTAGCAGCTCCATCTCACTGGATGTTGGNCAAATTGTCCGGTACTTATGCTCCAAGAC 
               
               
                   
               
               
                 CATCTGCTGGTCCACACANATTGAGAGAATCATTACCATTGGNTGTCTTTTTAAGAAACAGATTGNAGTA 
               
               
                   
               
               
                 TGCTTTGTGCGGTAGAGAAGTCAAAGCCATCATGATGCAACAACACGTTCAAGTTGTCGGTAAAGTCAGA 
               
               
                   
               
               
                 ACTGATACCACCTACCCAGCTGGTTTCATGGATGTCATCACCTTGGAAGCTACCAACGAACATTTCAGAT 
               
               
                   
               
               
                 TAGCCTACGATGTTAAAGGTAAATTCGCCGTTCACAGAATTTCTGCTGAAGAAGCTGTCTACAAATTGGG 
               
               
                   
               
               
                 TAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCACGACGGTAGAACTATC 
               
               
                   
               
               
                 AGATACCCAGATCCATTGATCAGAGCTAACGATACCGTTAAAATCGATTTGGCTACCGGTAAGATCGRTA 
               
               
                   
               
               
                 GTTTCATCAAATTCGACACTGGTAGATTAGTTATGGTTACTGGTGGTAGAAATTTGGGTAGAGTTGGTGT 
               
               
                   
               
               
                 TATTGTCCACAGAGAAAAACTCGAAGGAGGTTTCGATTTGGTCCACATCAAAGATGCTTTGGAAAACACT 
               
               
                   
               
               
                 TTCGTTACCAGATTGTCTAACGTTTTTGTTATTGGTACTGAAGCCGGTAAACCATGGGTCTCATTACCAA 
               
               
                   
               
               
                 AGGGTAAAGGTATCAAATTGTCTATTTCTGAAGAAAGAGACAGAAGAANAGCTCAACAAGGTTTGTAAGT 
               
               
                   
               
               
                 TTTATTCGCACTACAAAAAAAAAAATRTTTTRTGAAAATGAAAAAAACCAACGTAAATAATGTACATTAA 
               
               
                   
               
               
                 TTGCTAACCTTCAATAAGTTGTT 
               
               
                   
               
               
                 SEQ ID NO 203; RNA;  Candida albicans  SGY-243 
               
               
                 GAAUUCGUUGCUUGAGCAAGAGGAAAAGCUUACUAAAUUGAUAAAGCAGGCAAAUAGAAAUAGUACUUGG 
               
               
                   
               
               
                 UUCAAAUGGAAUAAAUAGUUUGUGUGUUGAUUUCGCGAAAAAGAAAUGUAAAGUAAUACUGAUUAGGGCU 
               
               
                   
               
               
                 AUAGCCCUAACUGGUUUCUCGCACUCUUUUCACUACCAAUUACUAAAAAAAAAAAAUUUGGUGAAAAAAA 
               
               
                   
               
               
                 AAAAUUAUCUACCACUCCCUAUACCAUCAUCAUCAACAAUAAACCCACAAUGGGUAGAGGUCCAAAGAAA 
               
               
                   
               
               
                 CACUUGAAAAGAUUAGCAGCUCCAUCUCACUGGAUGUUGGNCAAAUUGUCCGGUACUUAUGCUCCAAGAC 
               
               
                   
               
               
                 CAUCUGCUGGUCCACACANAUUGAGAGAAUCAUUACCAUUGGNUGUCUUUUUAAGAAACAGAUUGNAGUA 
               
               
                   
               
               
                 UGCUUUGUGCGGUAGAGAAGUCAAAGCCAUCAUGAUGCAACAACACGUUCAAGUUGUCGGUAAAGUCAGA 
               
               
                   
               
               
                 ACUGAUACCACCUACCCAGCUGGUUUCAUGGAUGUCAUCACCUUGGAAGCUACCAACGAACAUUUCAGAU 
               
               
                   
               
               
                 UAGCCUACGAUGUUAAAGGUAAAUUCGCCGUUCACAGAAUUUCUGCUGAAGAAGCUGUCUACAAAUUGGG 
               
               
                   
               
               
                 UAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCACGACGGUAGAACUAUC 
               
               
                   
               
               
                 AGAUACCCAGAUCCAUUGAUCAGAGCUAACGAUACCGUUAAAAUCGAUUUGGCUACCGGUAAGAUCGRUA 
               
               
                   
               
               
                 GUUUCAUCAAAUUCGACACUGGUAGAUUAGUUAUGGUUACUGGUGGUAGAAAUUUGGGUAGAGUUGGUGU 
               
               
                   
               
               
                 UAUUGUCCACAGAGAAAAACUCGAAGGAGGUUUCGAUUUGGUCCACAUCAAAGAUGCUUUGGAAAACACU 
               
               
                   
               
               
                 UUCGUUACCAGAUUGUCUAACGUUUUUGUUAUUGGUACUGAAGCCGGUAAACCAUGGGUCUCAUUACCAA 
               
               
                   
               
               
                 AGGGUAAAGGUAUCAAAUUGUCUAUUUCUGAAGAAAGAGACAGAAGAANAGCUCAACAAGGUUUGUAAGU 
               
               
                   
               
               
                 UUUAUUCGCACUACAAAAAAAAAAAURUUUURUGAAAAUGAAAAAAACCAACGUAAAUAAUGUACAUUAA 
               
               
                   
               
               
                 UUGCUAACCUUCAAUAAGUUGUU 
               
               
                   
               
               
                 SEQ ID NO 204; XM_446360.1  Candida glabrata  CBS138, partial mRNA 
               
               
                 ATGGCTAGAGGACCAAAGAAGCATCTAAAGAGATTAGCAGCTCCACACCACTGGTTGTTGGACAAGTTGT 
               
               
                   
               
               
                 CCGGCTGTTACGCCCCAAGACCATCCGCTGGTCCACACAAGTTGCGTGAATCCCTACCATTGATCGTTTT 
               
               
                   
               
               
                 CTTGAGAAACAGATTAAAGTACGCTTTGAACGGTCGTGAAGTTAAGGCTATCATGATGCAACGTCATGTT 
               
               
                   
               
               
                 AAGGTTGACGGTAAGGTCAGAACTGACGCTACCTACCCAGCTGGTTTCATGGATGTTATCACCTTGGAAG 
               
               
                   
               
               
                 CTACCAACGAAAACTTCAGATTGGTCTACGACGTCAAGGGTAGATTCGCTGTCCACCGTATCACTGACGA 
               
               
                   
               
               
                 AGAAGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTCCAATTGGGTAAGAAGGGTGTTCCATACGTTGTC 
               
               
                   
               
               
                 ACTGACGATGGTAGAACTATCAGATACCCAGACCCAAACATCAAGGTCAATGACACCGTCAAGGTCGACT 
               
               
                   
               
               
                 TGGCTTCCGGTAAGATCACTGACTACATCAAGTTCGACATTGGTAAGTTGGTCTACATCACCGGTGGTCG 
               
               
                   
               
               
                 TAACTTGGGTCGTATCGGTACCATCGTTCACAAGGAAAGACACGATGGTGGTTTCGACTTGGTTCACGTC 
               
               
                   
               
               
                 AAGGACTCCTTGGACAACACTTTCGTCACCAGATTGAACAACGTTTTCGTTATCGGTGAACAAGGTAAGC 
               
               
                   
               
               
                 CATACATCTCCTTGCCAAAGGGTAAGGGTATCAAGTTGACCATTGCTGAAGAACGTGACAGAAGAAGAGC 
               
               
                   
               
               
                 TCAACAAGGTTTATAA 
               
               
                   
               
               
                 SEQ ID NO 205; RNA  Candida glabrata  CBS138, partial mRNA 
               
               
                 AUGGCUAGAGGACCAAAGAAGCAUCUAAAGAGAUUAGCAGCUCCACACCACUGGUUGUUGGACAAGUUGU 
               
               
                   
               
               
                 CCGGCUGUUACGCCCCAAGACCAUCCGCUGGUCCACACAAGUUGCGUGAAUCCCUACCAUUGAUCGUUUU 
               
               
                   
               
               
                 CUUGAGAAACAGAUUAAAGUACGCUUUGAACGGUCGUGAAGUUAAGGCUAUCAUGAUGCAACGUCAUGUU 
               
               
                   
               
               
                 AAGGUUGACGGUAAGGUCAGAACUGACGCUACCUACCCAGCUGGUUUCAUGGAUGUUAUCACCUUGGAAG 
               
               
                   
               
               
                 CUACCAACGAAAACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACUGACGA 
               
               
                   
               
               
                 AGAAGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUCCAAUUGGGUAAGAAGGGUGUUCCAUACGUUGUC 
               
               
                   
               
               
                 ACUGACGAUGGUAGAACUAUCAGAUACCCAGACCCAAACAUCAAGGUCAAUGACACCGUCAAGGUCGACU 
               
               
                   
               
               
                 UGGCUUCCGGUAAGAUCACUGACUACAUCAAGUUCGACAUUGGUAAGUUGGUCUACAUCACCGGUGGUCG 
               
               
                   
               
               
                 UAACUUGGGUCGUAUCGGUACCAUCGUUCACAAGGAAAGACACGAUGGUGGUUUCGACUUGGUUCACGUC 
               
               
                   
               
               
                 AAGGACUCCUUGGACAACACUUUCGUCACCAGAUUGAACAACGUUUUCGUUAUCGGUGAACAAGGUAAGC 
               
               
                   
               
               
                 CAUACAUCUCCUUGCCAAAGGGUAAGGGUAUCAAGUUGACCAUUGCUGAAGAACGUGACAGAAGAAGAGC 
               
               
                   
               
               
                 UCAACAAGGUUUAUAA 
               
               
                   
               
               
                 SEQ ID NO 206; M64293.  S. cerevisiae  ribosomal protein S7 gene, exons 1 and 2 
               
               
                 GATCTAATCCTTCTCCTGGCCTACCGTCTGTGCAACCATTAGTCATGATTACGTGTGTTGCGCCTTATCT 
               
               
                   
               
               
                 TGTCATTATGGCAGCATACTTTTCGTAGTCCTTTCCTGCGCACGTTGTCCATTTTCGTAACCACGTAAAA 
               
               
                   
               
               
                 AGTCCTAATGGAGAGCTGGGTACTGCATTTTTTCGATGTTTTCAATATTCAGTTCAGCAGGAAATAAACA 
               
               
                   
               
               
                 AATAAACAAACATTAAAATATCTGGTTTTTTTTCCCAGAGACGCGTGGAAGCACCCATGCATCACTATTT 
               
               
                   
               
               
                 ATTTTTAAACAGCCGTACATTCTGTAATTTTGCTTCCTTTTTCTTCCTGCGTTCTTTTTTTCTTGAACTG 
               
               
                   
               
               
                 TCGTTTTCCGTTATTTTTTTCGGTGACATCAGTTGAAAGTAGCAGCGGCCTAGGCGACGGTAGCTCTTTG 
               
               
                   
               
               
                 TAGTCGTGGTAAGGGGGAGTAGCAATTCACTTAGTACGTGGTCTTGGAGTTAGGCTGGCTCGGACTGGCC 
               
               
                   
               
               
                 CTGGCAAGTCCTGTTCTGTGTGGTAGTATTGAAATTTCAGAGATTGTCGGCAATACTAGTATATTAAAAA 
               
               
                   
               
               
                 TTATACTATAATTTAATCTAGTGTTGAAATACTTTCTTATATAGCGATTTTTCTGCCCAAAACAAACCAA 
               
               
                   
               
               
                 AGAATCAATACGCAAAGATGGCTAGAGGACCGTATGTTTGACTATAGACTTTGATTATAATTACGCAAGG 
               
               
                   
               
               
                 ATGAGAAGAATGATAGACAAGAAACAAGTGGAGTCTTAACCAAACGAATAGGAACAACAATGAACCAGTT 
               
               
                   
               
               
                 TATGTCCATTTAATTTTAGATCATCCTGGGATTGTACAAATATTTTACGAGTAATGATTTACTAACGAGC 
               
               
                   
               
               
                 ACAATGAAAAAAATAAAATGTCTGTATCTTCATTATACATTCATTTTTGCCCTTTTTTCTCATTTTTTTC 
               
               
                   
               
               
                 CGTACAGAAAGAAGCATCTAAAAAGATTAGCAGCTCCACACCACTGGTTATTGGACAAGTTGTCCGGTTG 
               
               
                   
               
               
                 TTACGCCCCAAGACCATCTGCTGGTCCACACAAATTGCGTGAATCCTTGCCATTGATTGTCTTTCTAAGA 
               
               
                   
               
               
                 AACAGATTAAAGTATGCTTTGAACGGCCGTGAAGTCAAGGCTATCTTGATGCAACGTCACGTTAAAGTGG 
               
               
                   
               
               
                 ACGGTAAGGTTAGAACCGACACTACCTACCCAGCTGGTTTCATGGATGTCATCACTCTAGATGCCACCAA 
               
               
                   
               
               
                 TGAAAACTTCAGATTGGTCTACGATGTCAAGGGTAGATTCGCTGTCCACCGTATCACCGATGAAGAAGCT 
               
               
                   
               
               
                 TCTTACAAGTTGGGTAAGGTCAAGAAGGTTCAATTAGGTAAGAAGGGTGTTCCATACGTTGTTACCCACG 
               
               
                   
               
               
                 ATGGTAGAACTATCAGATACCCAGACCCAAACATCAAGGTCAATGACACTGTTAAGATCGACTTGGCCTC 
               
               
                   
               
               
                 TGGTAAGATTACTGATTTCATCAAGTTCGATGCCGGTAAGTTGGTTTACGTTACTGGTGGTCGTAACTTG 
               
               
                   
               
               
                 GGTCGTATCGGTACTATCGTTCACAAGGAAAGACACGATGGTGGTTTCGATTTAGTTCACATCAAGGACT 
               
               
                   
               
               
                 CCTTGGACAACACTTTCGTCACTAGATTGAACAATGTCTTCGTCATCGGTGAACAAGGTAAGCCTTACAT 
               
               
                   
               
               
                 TTCTTTGCCAAAGGGTAAGGGTATCAAGTTGTCTATTGCTGAAGAACGTGACAGAAGAAGAGCTCAACAA 
               
               
                   
               
               
                 GGTTTATAAATTTCATAACAACTTAATTATTTTCTTCTTTTGTATATCTCCATTAATGTTTATTAGAAAT 
               
               
                   
               
               
                 TGAATTTTAAAATAATACATCGTATCTTCCTTTTTCGACTGGCAGTAATATAACGTATAATATATATATT 
               
               
                   
               
               
                 AGGTGTGTGTATATATATCCGTATTGTAATATTGATAGTAAAAATACGCTAACCCTGAAATAGAAGGCGT 
               
               
                   
               
               
                 ATGATAAGACGTACTGACACTACGCACTACCACAATATATGCGTTGTGTGTGTGTGTGTGTGTGTGTGTG 
               
               
                   
               
               
                 TGTGTGATTGTATTGGAATATATATACTTACTAAAATTAAGCTTATATGGTTCGCATATTGACTATTTAT 
               
               
                   
               
               
                 AAGGATATTCAACTTGTATGTCCTTTCTTAACCAAATTTTCTTCTTTCTCTTGGTGGTAACATGTTCCAC 
               
               
                   
               
               
                 AAACTTCTCAGTACAATGATCCACTTTGAATTTCTTTATGAAAACAGGGTCCCATAATTCAGAACCGACG 
               
               
                   
               
               
                 CCGAGATC 
               
               
                   
               
               
                 SEQ ID NO 207; RNA  S. cerevisiae  ribosomal protein S7 gene, exons 1 and 2 
               
               
                 GAUCUAAUCCUUCUCCUGGCCUACCGUCUGUGCAACCAUUAGUCAUGAUUACGUGUGUUGCGCCUUAUCU 
               
               
                   
               
               
                 UGUCAUUAUGGCAGCAUACUUUUCGUAGUCCUUUCCUGCGCACGUUGUCCAUUUUCGUAACCACGUAAAA 
               
               
                   
               
               
                 AGUCCUAAUGGAGAGCUGGGUACUGCAUUUUUUCGAUGUUUUCAAUAUUCAGUUCAGCAGGAAAUAAACA 
               
               
                   
               
               
                 AAUAAACAAACAUUAAAAUAUCUGGUUUUUUUUCCCAGAGACGCGUGGAAGCACCCAUGCAUCACUAUUU 
               
               
                   
               
               
                 AUUUUUAAACAGCCGUACAUUCUGUAAUUUUGCUUCCUUUUUCUUCCUGCGUUCUUUUUUUCUUGAACUG 
               
               
                   
               
               
                 UCGUUUUCCGUUAUUUUUUUCGGUGACAUCAGUUGAAAGUAGCAGCGGCCUAGGCGACGGUAGCUCUUUG 
               
               
                   
               
               
                 UAGUCGUGGUAAGGGGGAGUAGCAAUUCACUUAGUACGUGGUCUUGGAGUUAGGCUGGCUCGGACUGGCC 
               
               
                   
               
               
                 CUGGCAAGUCCUGUUCUGUGUGGUAGUAUUGAAAUUUCAGAGAUUGUCGGCAAUACUAGUAUAUUAAAAA 
               
               
                   
               
               
                 UUAUACUAUAAUUUAAUCUAGUGUUGAAAUACUUUCUUAUAUAGCGAUUUUUCUGCCCAAAACAAACCAA 
               
               
                   
               
               
                 AGAAUCAAUACGCAAAGAUGGCUAGAGGACCGUAUGUUUGACUAUAGACUUUGAUUAUAAUUACGCAAGG 
               
               
                   
               
               
                 AUGAGAAGAAUGAUAGACAAGAAACAAGUGGAGUCUUAACCAAACGAAUAGGAACAACAAUGAACCAGUU 
               
               
                   
               
               
                 UAUGUCCAUUUAAUUUUAGAUCAUCCUGGGAUUGUACAAAUAUUUUACGAGUAAUGAUUUACUAACGAGC 
               
               
                   
               
               
                 ACAAUGAAAAAAAUAAAAUGUCUGUAUCUUCAUUAUACAUUCAUUUUUGCCCUUUUUUCUCAUUUUUUUC 
               
               
                   
               
               
                 CGUACAGAAAGAAGCAUCUAAAAAGAUUAGCAGCUCCACACCACUGGUUAUUGGACAAGUUGUCCGGUUG 
               
               
                   
               
               
                 UUACGCCCCAAGACCAUCUGCUGGUCCACACAAAUUGCGUGAAUCCUUGCCAUUGAUUGUCUUUCUAAGA 
               
               
                   
               
               
                 AACAGAUUAAAGUAUGCUUUGAACGGCCGUGAAGUCAAGGCUAUCUUGAUGCAACGUCACGUUAAAGUGG 
               
               
                   
               
               
                 ACGGUAAGGUUAGAACCGACACUACCUACCCAGCUGGUUUCAUGGAUGUCAUCACUCUAGAUGCCACCAA 
               
               
                   
               
               
                 UGAAAACUUCAGAUUGGUCUACGAUGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACCGAUGAAGAAGCU 
               
               
                   
               
               
                 UCUUACAAGUUGGGUAAGGUCAAGAAGGUUCAAUUAGGUAAGAAGGGUGUUCCAUACGUUGUUACCCACG 
               
               
                   
               
               
                 AUGGUAGAACUAUCAGAUACCCAGACCCAAACAUCAAGGUCAAUGACACUGUUAAGAUCGACUUGGCCUC 
               
               
                   
               
               
                 UGGUAAGAUUACUGAUUUCAUCAAGUUCGAUGCCGGUAAGUUGGUUUACGUUACUGGUGGUCGUAACUUG 
               
               
                   
               
               
                 GGUCGUAUCGGUACUAUCGUUCACAAGGAAAGACACGAUGGUGGUUUCGAUUUAGUUCACAUCAAGGACU 
               
               
                   
               
               
                 CCUUGGACAACACUUUCGUCACUAGAUUGAACAAUGUCUUCGUCAUCGGUGAACAAGGUAAGCCUUACAU 
               
               
                   
               
               
                 UUCUUUGCCAAAGGGUAAGGGUAUCAAGUUGUCUAUUGCUGAAGAACGUGACAGAAGAAGAGCUCAACAA 
               
               
                   
               
               
                 GGUUUAUAAAUUUCAUAACAACUUAAUUAUUUUCUUCUUUUGUAUAUCUCCAUUAAUGUUUAUUAGAAAU 
               
               
                   
               
               
                 UGAAUUUUAAAAUAAUACAUCGUAUCUUCCUUUUUCGACUGGCAGUAAUAUAACGUAUAAUAUAUAUAUU 
               
               
                   
               
               
                 AGGUGUGUGUAUAUAUAUCCGUAUUGUAAUAUUGAUAGUAAAAAUACGCUAACCCUGAAAUAGAAGGCGU 
               
               
                   
               
               
                 AUGAUAAGACGUACUGACACUACGCACUACCACAAUAUAUGCGUUGUGUGUGUGUGUGUGUGUGUGUGUG 
               
               
                   
               
               
                 UGUGUGAUUGUAUUGGAAUAUAUAUACUUACUAAAAUUAAGCUUAUAUGGUUCGCAUAUUGACUAUUUAU 
               
               
                   
               
               
                 AAGGAUAUUCAACUUGUAUGUCCUUUCUUAACCAAAUUUUCUUCUUUCUCUUGGUGGUAACAUGUUCCAC 
               
               
                   
               
               
                 AAACUUCUCAGUACAAUGAUCCACUUUGAAUUUCUUUAUGAAAACAGGGUCCCAUAAUUCAGAACCGACG 
               
               
                   
               
               
                 CCGAGAUC 
               
               
                   
               
               
                 SEQ ID NO 208; M64294. A  S. cerevisiae  ribosomal protein S7 gene, exons 1 and 2 
               
               
                 GTAAGATTTAGAATAGTTTCTTTTCATATAACGTCGACTAAGTATAACAATAGATACACCACTATTGAGG 
               
               
                   
               
               
                 AAAGATGGCTAGAGGACCGTATGTTGATTTCCACCTAAAAAAATGAAGAGTTGGCAAAACAAGATAATAG 
               
               
                   
               
               
                 TTTTCTTTGAAGATGGGTACCCTCTCATGATTGGTACAAGTGATTTGCACCAAAGTGACGATGCGGACTA 
               
               
                   
               
               
                 AAGAAAGAATATAAGAAGTTGTGTTTATCTATCGGAAGATAGAATTCTGATGAGAAAACTTTATCCTTGT 
               
               
                   
               
               
                 TAAGAACAGATAAGCATTGCGGGATATTTTTACTAACAAGAGTACGTTTAATAATGTTAATACGATTTTT 
               
               
                   
               
               
                 CATATAGAAAGAAGCATCTAAAGAGATTAGCAGCTCCACACCATTGGTTATTGGACAAGTTGTCCGGTTG 
               
               
                   
               
               
                 TTACGCCCCAAGACCATCTGCTGGTCCACACAAATTGCGTGAATCCTTGCCATTGATTGTCTTTCTAAGA 
               
               
                   
               
               
                 AACAGATTAAAGTATGCTTTGAACGGCCGTGAAGTCAAGGCTATCTTGATGCAACGTCACGTCAAAGTTG 
               
               
                   
               
               
                 ACGGTAAGGTTAGAACTGACACCACCTACCCAGCTGGTTTCATGGACGTCATCACTCTAGATGCCACCAA 
               
               
                   
               
               
                 TGAAAACTTCAGATTGGTCTACGATGTCAAGGGTAGATTCGCTGTCCACCGTATCACCGATGAAGAAGCC 
               
               
                   
               
               
                 TCTTACAAATTGGGTAAGGTCAAGAAGGTTCAATTAGGTAAGAAGGGTGTTCCATACGTTGTTACCCACG 
               
               
                   
               
               
                 ATGGTAGAACTATCAGATACCCAGACCCAAACATCAAGGTCAATGACACTGTTAAGATTGATTTGGCCTC 
               
               
                   
               
               
                 TGGTAAGATTACTGATTTCATCAAGTTCGATGCCGGTAAGTTGGTTTACGTTACTGGTGGTCGTAACTTG 
               
               
                   
               
               
                 GGTCGTATCGGTACTATCGTTCACAAGGAAAGACACGATGGTGGTTTCGATTTGGTTCACATCAAGGACT 
               
               
                   
               
               
                 CCTTGGACAACACTTTCGTCACTAGATTGAACAATGTCTTCGTCATTGGTGAACAAGGTAAGCCTTACAT 
               
               
                   
               
               
                 TTCTTTGCCAAAGGGTAAGGGTATCAAGTTGTCTATTGCTGAAGAACGTGACAGAAGAAGAGCTCAACAA 
               
               
                   
               
               
                 GGTTTGTAAACATTTTAAATATTGTTATCTGCCCTCTCTTCGTCTTTTG 
               
               
                   
               
               
                 SEQ ID NO 209; RNA A  S. cerevisiae  ribosomal protein S7 gene, exons 1 and 2 
               
               
                 GUAAGAUUUAGAAUAGUUUCUUUUCAUAUAACGUCGACUAAGUAUAACAAUAGAUACACCACUAUUGAGG 
               
               
                   
               
               
                 AAAGAUGGCUAGAGGACCGUAUGUUGAUUUCCACCUAAAAAAAUGAAGAGUUGGCAAAACAAGAUAAUAG 
               
               
                   
               
               
                 UUUUCUUUGAAGAUGGGUACCCUCUCAUGAUUGGUACAAGUGAUUUGCACCAAAGUGACGAUGCGGACUA 
               
               
                   
               
               
                 AAGAAAGAAUAUAAGAAGUUGUGUUUAUCUAUCGGAAGAUAGAAUUCUGAUGAGAAAACUUUAUCCUUGU 
               
               
                   
               
               
                 UAAGAACAGAUAAGCAUUGCGGGAUAUUUUUACUAACAAGAGUACGUUUAAUAAUGUUAAUACGAUUUUU 
               
               
                   
               
               
                 CAUAUAGAAAGAAGCAUCUAAAGAGAUUAGCAGCUCCACACCAUUGGUUAUUGGACAAGUUGUCCGGUUG 
               
               
                   
               
               
                 UUACGCCCCAAGACCAUCUGCUGGUCCACACAAAUUGCGUGAAUCCUUGCCAUUGAUUGUCUUUCUAAGA 
               
               
                   
               
               
                 AACAGAUUAAAGUAUGCUUUGAACGGCCGUGAAGUCAAGGCUAUCUUGAUGCAACGUCACGUCAAAGUUG 
               
               
                   
               
               
                 ACGGUAAGGUUAGAACUGACACCACCUACCCAGCUGGUUUCAUGGACGUCAUCACUCUAGAUGCCACCAA 
               
               
                   
               
               
                 UGAAAACUUCAGAUUGGUCUACGAUGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACCGAUGAAGAAGCC 
               
               
                   
               
               
                 UCUUACAAAUUGGGUAAGGUCAAGAAGGUUCAAUUAGGUAAGAAGGGUGUUCCAUACGUUGUUACCCACG 
               
               
                   
               
               
                 AUGGUAGAACUAUCAGAUACCCAGACCCAAACAUCAAGGUCAAUGACACUGUUAAGAUUGAUUUGGCCUC 
               
               
                   
               
               
                 UGGUAAGAUUACUGAUUUCAUCAAGUUCGAUGCCGGUAAGUUGGUUUACGUUACUGGUGGUCGUAACUUG 
               
               
                   
               
               
                 GGUCGUAUCGGUACUAUCGUUCACAAGGAAAGACACGAUGGUGGUUUCGAUUUGGUUCACAUCAAGGACU 
               
               
                   
               
               
                 CCUUGGACAACACUUUCGUCACUAGAUUGAACAAUGUCUUCGUCAUUGGUGAACAAGGUAAGCCUUACAU 
               
               
                   
               
               
                 UUCUUUGCCAAAGGGUAAGGGUAUCAAGUUGUCUAUUGCUGAAGAACGUGACAGAAGAAGAGCUCAACAA 
               
               
                   
               
               
                 GGUUUGUAAACAUUUUAAAUAUUGUUAUCUGCCCUCUCUUCGUCUUUUG 
               
               
                   
               
               
                 SEQ ID NO 210 
               
               
                 XM_451697.1  Kluyveromyces lactis  NRRL Y-1140, KLLA0B03652g predicted mRNA 
               
               
                 ATGGCTAGAGGACCAAAGAAGCATCTAAAGAGATTAGCAGCTCCACATCATTGGATGTTGGACAAGTTGT 
               
               
                   
               
               
                 CCGGTTGTTACGCACCAAGACCATCTGCTGGTCCACACAAGTTGCGTGAATCCTTGCCATTGATCGTTTT 
               
               
                   
               
               
                 CTTGAGAAACAGATTAAAGTATGCTTTGAACGGTCGTGAAGTCAAGGCCATCTTGATGCAACGTCATGTC 
               
               
                   
               
               
                 AAGGTTGACGGTAAGGTCAGAACCGACACTACTTTCCCAGCTGGTTTCATGGATGTTATCACCTTGGAAG 
               
               
                   
               
               
                 CTACCAACGAAAACTTCAGATTGGTCTACGATGTTAAGGGTAGATTCGCTGTCCACCGTATCACTGATGA 
               
               
                   
               
               
                 AGAAGCTTCCTACAAGTTGGCTAAGGTCAAGAAGGTTCAACTAGGTAAGAAGGGTATTCCATACGTCGTT 
               
               
                   
               
               
                 ACCCACGACGGTAGAACCATCAGATACCCAGACCCAAACATCAAGGTTAACGACACCGTTAAGGTTGATT 
               
               
                   
               
               
                 TGGCTACTGGTACTATCACCGATTTCATCAAATTCGACACTGGTAAGTTGGTTTATGTTACCGGTGGTCG 
               
               
                   
               
               
                 TAACTTGGGTAGAGTTGGTACCATCGTCCACAGAGAAAGACACGAAGGTGGTTTCGATTTGGTTCACATC 
               
               
                   
               
               
                 AAGGATTCTTTGGAAAACACTTTCGTCACCAGATTGAACAACGTTTTCGTCATCGGTGAACCAGGTAGAC 
               
               
                   
               
               
                 CATGGATCTCCTTGCCAAAGGGTAAGGGTATCAAGTTGACCATCTCTGAAGAACGTGACCGTAGAAGAGC 
               
               
                   
               
               
                 TCAACATGGTTTGTAA 
               
               
                   
               
               
                 SEQ ID NO 211 
               
               
                 RNA  Kluyveromyces lactis  NRRL Y-1140, KLLA0B03652g predicted mRNA 
               
               
                 AUGGCUAGAGGACCAAAGAAGCAUCUAAAGAGAUUAGCAGCUCCACAUCAUUGGAUGUUGGACAAGUUGU 
               
               
                   
               
               
                 CCGGUUGUUACGCACCAAGACCAUCUGCUGGUCCACACAAGUUGCGUGAAUCCUUGCCAUUGAUCGUUUU 
               
               
                   
               
               
                 CUUGAGAAACAGAUUAAAGUAUGCUUUGAACGGUCGUGAAGUCAAGGCCAUCUUGAUGCAACGUCAUGUC 
               
               
                   
               
               
                 AAGGUUGACGGUAAGGUCAGAACCGACACUACUUUCCCAGCUGGUUUCAUGGAUGUUAUCACCUUGGAAG 
               
               
                   
               
               
                 CUACCAACGAAAACUUCAGAUUGGUCUACGAUGUUAAGGGUAGAUUCGCUGUCCACCGUAUCACUGAUGA 
               
               
                   
               
               
                 AGAAGCUUCCUACAAGUUGGCUAAGGUCAAGAAGGUUCAACUAGGUAAGAAGGGUAUUCCAUACGUCGUU 
               
               
                   
               
               
                 ACCCACGACGGUAGAACCAUCAGAUACCCAGACCCAAACAUCAAGGUUAACGACACCGUUAAGGUUGAUU 
               
               
                   
               
               
                 UGGCUACUGGUACUAUCACCGAUUUCAUCAAAUUCGACACUGGUAAGUUGGUUUAUGUUACCGGUGGUCG 
               
               
                   
               
               
                 UAACUUGGGUAGAGUUGGUACCAUCGUCCACAGAGAAAGACACGAAGGUGGUUUCGAUUUGGUUCACAUC 
               
               
                   
               
               
                 AAGGAUUCUUUGGAAAACACUUUCGUCACCAGAUUGAACAACGUUUUCGUCAUCGGUGAACCAGGUAGAC 
               
               
                   
               
               
                 CAUGGAUCUCCUUGCCAAAGGGUAAGGGUAUCAAGUUGACCAUCUCUGAAGAACGUGACCGUAGAAGAGC 
               
               
                   
               
               
                 UCAACAUGGUUUGUAA 
               
               
                   
               
               
                 SEQ ID NO 212; NM_209058.1|  Eremothecium gossypii  ADL391Cp (ADL391C), mRNA 
               
               
                 ATGGCTAGAGGACCAAAGAAGCACCTGAAGAGATTGGCAGCTCCACACCACTGGTTGTTGGACAAGCTAT 
               
               
                   
               
               
                 CCGGCTGTTACGCTCCAAGACCATCCGCTGGTCCACACAAGTTGCGCGAGTCTTTGCCATTGATCGTCTT 
               
               
                   
               
               
                 CTTGAGAAACAGATTAAAGTATGCTTTGAACGGTCGCGAGGTCAAGGCCATCCTAATGCAGCGTCATGTT 
               
               
                   
               
               
                 AAGGTTGACGGTAAGGTCAGAACTGACACTACCTACCCAGCTGGTTTCATGGATGTCATCACTCTAGAGG 
               
               
                   
               
               
                 CTACCAACGAGAACTTCAGATTGGTATACGATGTCAAGGGCAGATTTGCTGTCCACCGTATCACCGATGA 
               
               
                   
               
               
                 GGAGGCTACTTACAAGTTGGGTAAGGTTAAGCGCGTTCAGCTAGGTAAGAAGGGTGTCCCATACGTGGTC 
               
               
                   
               
               
                 ACTCACGACGGCAGAACCATCAGATACCCAGACCCAAACATCAAGGTTAACGACACCGTCAAGGTTGACC 
               
               
                   
               
               
                 TTGCTACTGGTAAGATTACCGACTTCATCAAGTTCGACACTGGTAAGTTGGTGTACGTCACCGGTGGCCG 
               
               
                   
               
               
                 TAACTTGGGCCGTATTGGTGTCATCACCCACAGAGAGAGACACGAGGGTGGCTTTGACTTGGTTCACATC 
               
               
                   
               
               
                 AAGGACTCCTTGGAGAACACTTTCGTCACCAGATTGAACAACGTTTTCGTCATCGGTGAGCAAGGTAGAC 
               
               
                   
               
               
                 CATGGATCTCCTTGCCAAGGGGTAAGGGTATTAAGTTGTCCATTGCTGAGGAGCGTGACCGTAGAAGAGC 
               
               
                   
               
               
                 TCAACAAGGTTTGTAA 
               
               
                   
               
               
                 SEQ ID NO 213; RNA  Eremothecium gossypii  ADL391Cp (ADL391C), mRNA 
               
               
                 AUGGCUAGAGGACCAAAGAAGCACCUGAAGAGAUUGGCAGCUCCACACCACUGGUUGUUGGACAAGCUAU 
               
               
                   
               
               
                 CCGGCUGUUACGCUCCAAGACCAUCCGCUGGUCCACACAAGUUGCGCGAGUCUUUGCCAUUGAUCGUCUU 
               
               
                   
               
               
                 CUUGAGAAACAGAUUAAAGUAUGCUUUGAACGGUCGCGAGGUCAAGGCCAUCCUAAUGCAGCGUCAUGUU 
               
               
                   
               
               
                 AAGGUUGACGGUAAGGUCAGAACUGACACUACCUACCCAGCUGGUUUCAUGGAUGUCAUCACUCUAGAGG 
               
               
                   
               
               
                 CUACCAACGAGAACUUCAGAUUGGUAUACGAUGUCAAGGGCAGAUUUGCUGUCCACCGUAUCACCGAUGA 
               
               
                   
               
               
                 GGAGGCUACUUACAAGUUGGGUAAGGUUAAGCGCGUUCAGCUAGGUAAGAAGGGUGUCCCAUACGUGGUC 
               
               
                   
               
               
                 ACUCACGACGGCAGAACCAUCAGAUACCCAGACCCAAACAUCAAGGUUAACGACACCGUCAAGGUUGACC 
               
               
                   
               
               
                 UUGCUACUGGUAAGAUUACCGACUUCAUCAAGUUCGACACUGGUAAGUUGGUGUACGUCACCGGUGGCCG 
               
               
                   
               
               
                 UAACUUGGGCCGUAUUGGUGUCAUCACCCACAGAGAGAGACACGAGGGUGGCUUUGACUUGGUUCACAUC 
               
               
                   
               
               
                 AAGGACUCCUUGGAGAACACUUUCGUCACCAGAUUGAACAACGUUUUCGUCAUCGGUGAGCAAGGUAGAC 
               
               
                   
               
               
                 CAUGGAUCUCCUUGCCAAGGGGUAAGGGUAUUAAGUUGUCCAUUGCUGAGGAGCGUGACCGUAGAAGAGC 
               
               
                   
               
               
                 UCAACAAGGUUUGUAA 
               
               
                   
               
               
                 SEQ ID NO 214; XM_460509.1  Debaryomyces hansenii  CBS767 hypothetical 
               
               
                 protein (DEHA0F03674g) partial mRNA 
               
               
                 ATGGGTAGAGGTCCAAAGAAGCACTTGAAGAGATTAGCAGCACCATCCCACTGGATGTTGGACAAATTGT 
               
               
                   
               
               
                 CCGGTACTTACGCACCAAGACCATCTGCTGGTCCTCACAAATTGAGAGAATCTTTACCATTGGTTATCTT 
               
               
                   
               
               
                 CTTAAGAAACAGACTTAAGTATGCCTTAAACGGTAGAGAAGTCAAGGCCATCTTGATGCAAGAACACGTC 
               
               
                   
               
               
                 AAGGTTGATGGTAAAGTTAGAACCGATGCTACTTTCCCAGCTGGTTTCATGGATGTCATCACTTTAGAAG 
               
               
                   
               
               
                 CTACCAACGAACACTTCAGATTAATCTATGATGTCAAGGGTAGATTCACTGTCCACAGAATCACTGCTGA 
               
               
                   
               
               
                 AGAAGCTTCTTACAAGTTAGCTAAGGTCAAGAAGGTCCAATTAGGTAAGAGAGGTATTCCATACGTTGTC 
               
               
                   
               
               
                 ACCCACGACGGTAGAACTATCAGATACCCAGATCCATTGATCAGAGCCAACGATTCCGTTAAGGTTGACT 
               
               
                   
               
               
                 TAGCTACCGGTAAGATCACTGACTTTATCAGCTTTGACACTGGTAGATTAGTCATGGTTACTGGTGGTCG 
               
               
                   
               
               
                 TAACATGGGTAGAGTTGGTGTTATCACCCACAGAGAAAAGCACGAGGGTGGTTTCGATTTAGTCCACATC 
               
               
                   
               
               
                 AAGGATTCTTTGGAAAACACTTTCGTTACCAGATTAACTAACGTCTTCATCGTCGGTACTGAAGCTGGTA 
               
               
                   
               
               
                 AGCCACACATTTCTTTACCAAAGGGTAAGGGTATTAAGTTATCCATCTCTGAAGAACGTGACAGAAGAAG 
               
               
                   
               
               
                 AAACCAACAACTTATCAACTAA 
               
               
                   
               
               
                 SEQ ID NO 215; RNA  Debaryomyces hansenii  CBS767 hypothetical 
               
               
                 protein (DEHA0F03674g) partial mRNA 
               
               
                 AUGGGUAGAGGUCCAAAGAAGCACUUGAAGAGAUUAGCAGCACCAUCCCACUGGAUGUUGGACAAAUUGU 
               
               
                   
               
               
                 CCGGUACUUACGCACCAAGACCAUCUGCUGGUCCUCACAAAUUGAGAGAAUCUUUACCAUUGGUUAUCUU 
               
               
                   
               
               
                 CUUAAGAAACAGACUUAAGUAUGCCUUAAACGGUAGAGAAGUCAAGGCCAUCUUGAUGCAAGAACACGUC 
               
               
                   
               
               
                 AAGGUUGAUGGUAAAGUUAGAACCGAUGCUACUUUCCCAGCUGGUUUCAUGGAUGUCAUCACUUUAGAAG 
               
               
                   
               
               
                 CUACCAACGAACACUUCAGAUUAAUCUAUGAUGUCAAGGGUAGAUUCACUGUCCACAGAAUCACUGCUGA 
               
               
                   
               
               
                 AGAAGCUUCUUACAAGUUAGCUAAGGUCAAGAAGGUCCAAUUAGGUAAGAGAGGUAUUCCAUACGUUGUC 
               
               
                   
               
               
                 ACCCACGACGGUAGAACUAUCAGAUACCCAGAUCCAUUGAUCAGAGCCAACGAUUCCGUUAAGGUUGACU 
               
               
                   
               
               
                 UAGCUACCGGUAAGAUCACUGACUUUAUCAGCUUUGACACUGGUAGAUUAGUCAUGGUUACUGGUGGUCG 
               
               
                   
               
               
                 UAACAUGGGUAGAGUUGGUGUUAUCACCCACAGAGAAAAGCACGAGGGUGGUUUCGAUUUAGUCCACAUC 
               
               
                   
               
               
                 AAGGAUUCUUUGGAAAACACUUUCGUUACCAGAUUAACUAACGUCUUCAUCGUCGGUACUGAAGCUGGUA 
               
               
                   
               
               
                 AGCCACACAUUUCUUUACCAAAGGGUAAGGGUAUUAAGUUAUCCAUCUCUGAAGAACGUGACAGAAGAAG 
               
               
                   
               
               
                 AAACCAACAACUUAUCAACUAA 
               
               
                   
               
               
                 SEQ ID NO 216; XM_657428.1  Aspergillus nidulans  FGSC A4 40S ribosomal 
               
               
                 protein S7 (AN4916.2), mRNA 
               
               
                 ATGGCTGCCATCAACAAGATCGCCCACAACTCGCCGTCGAGGCAGAACCCTTCCGAGCTGGAGACCGCGA 
               
               
                   
               
               
                 TCGCGGGTGCTCTCTTCGACTTGGAGAGCAACACACAGGACCTGAAGGCTACTCTCCGGCCTCTGCAGTT 
               
               
                   
               
               
                 CGTGTCTGCTCGTGAGGTCGAGGTCGGCCACGGCAAGAAGGCTGTCATCATCTTCGTCCCCGTCCCTCTC 
               
               
                   
               
               
                 CTCCAGGCCTTCCACAAGATCCAGCAGCGCCTTACCCGTGAACTCGAGAAGAAGTTCTCGGACCGCCACG 
               
               
                   
               
               
                 TCCTCTTCGTCGCTCAGCGCCGCATCCTCCCCAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGCCCCCGTTCCCGTACCCTTACTGCCGTTCACGACGCCATCCTCGACGACCTCGTCTACCCC 
               
               
                   
               
               
                 GTTGAGATTGTCGGCAAGCGCATCCGCACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTCGACG 
               
               
                   
               
               
                 AGAAGGAGCGTGGTGGTGTTGACCACCGCCTCGACGCCTACGGCGAGGTCTACCGTCGTCTGACGGGTCG 
               
               
                   
               
               
                 TGCTGTCGTTTTCGAGTTCCCCCAGGGTGGTGCTTCTGAGTTTTAA 
               
               
                   
               
               
                 SEQ ID NO 217; RNA  Aspergillus nidulans  FGSC A4 40S ribosomal 
               
               
                 protein S7 (AN4916.2), mRNA 
               
               
                 AUGGCUGCCAUCAACAAGAUCGCCCACAACUCGCCGUCGAGGCAGAACCCUUCCGAGCUGGAGACCGCGA 
               
               
                   
               
               
                 UCGCGGGUGCUCUCUUCGACUUGGAGAGCAACACACAGGACCUGAAGGCUACUCUCCGGCCUCUGCAGUU 
               
               
                   
               
               
                 CGUGUCUGCUCGUGAGGUCGAGGUCGGCCACGGCAAGAAGGCUGUCAUCAUCUUCGUCCCCGUCCCUCUC 
               
               
                   
               
               
                 CUCCAGGCCUUCCACAAGAUCCAGCAGCGCCUUACCCGUGAACUCGAGAAGAAGUUCUCGGACCGCCACG 
               
               
                   
               
               
                 UCCUCUUCGUCGCUCAGCGCCGCAUCCUCCCCAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGCCCCCGUUCCCGUACCCUUACUGCCGUUCACGACGCCAUCCUCGACGACCUCGUCUACCCC 
               
               
                   
               
               
                 GUUGAGAUUGUCGGCAAGCGCAUCCGCACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUCGACG 
               
               
                   
               
               
                 AGAAGGAGCGUGGUGGUGUUGACCACCGCCUCGACGCCUACGGCGAGGUCUACCGUCGUCUGACGGGUCG 
               
               
                   
               
               
                 UGCUGUCGUUUUCGAGUUCCCCCAGGGUGGUGCUUCUGAGUUUUAA 
               
               
                   
               
               
                 SEQ ID NO 218; &gt;XM_749453.1  Aspergillus fumigatus  Af293 ribosomal 
               
               
                 protein S7e (Afu3g10730) partial mRNA 
               
               
                 ATGGCTGCTATCAACAAGATCGCCCACAACTCGCCATCGAGGCAGAACCCCTCCGAGCTGGAGACTGCGA 
               
               
                   
               
               
                 TCGCCGGCGCTCTCTACGACTTGGAGAGCAATACACAGGACCTGAAGGCCACCCTTCGGCCCCTGCAGTT 
               
               
                   
               
               
                 TGTCTCTGCCCGTGAGGTTGAGGTCGGCCACGGCAAGAAGGCCGTTATCATCTTCGTCCCCGTCCCTCTC 
               
               
                   
               
               
                 CTCCAGGGCTTCCACAAGATCCAGCAGCGCCTGACCCGTGAGCTCGAGAAGAAGTTCTCCGACCGCCACG 
               
               
                   
               
               
                 TCCTCTTTGTTGCTCAGCGCCGCATCCTGCCCCGCCCTAAGCGCTCTGTCAACTCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGTCCTCGCTCTCGCACCCTGACCGCTGTCCACGACGCCATCCTCAACGACCTCGTTTACCCC 
               
               
                   
               
               
                 GTCGAGATCGTCGGCAAGCGTATCCGCACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACG 
               
               
                   
               
               
                 AGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGCCTACGGCGAGGTTTACCGCCGACTAACCGGCCG 
               
               
                   
               
               
                 CTCTGTTGTCTTCGAGTTCCCCCAGAGCGGTGCCGCCGAGTACTAG 
               
               
                   
               
               
                 SEQ ID NO 219; RNA  Aspergillus fumigatus  Af293 ribosomal protein S7e 
               
               
                 (Afu3g10730) partial mRNA 
               
               
                 AUGGCUGCUAUCAACAAGAUCGCCCACAACUCGCCAUCGAGGCAGAACCCCUCCGAGCUGGAGACUGCGA 
               
               
                   
               
               
                 UCGCCGGCGCUCUCUACGACUUGGAGAGCAAUACACAGGACCUGAAGGCCACCCUUCGGCCCCUGCAGUU 
               
               
                   
               
               
                 UGUCUCUGCCCGUGAGGUUGAGGUCGGCCACGGCAAGAAGGCCGUUAUCAUCUUCGUCCCCGUCCCUCUC 
               
               
                   
               
               
                 CUCCAGGGCUUCCACAAGAUCCAGCAGCGCCUGACCCGUGAGCUCGAGAAGAAGUUCUCCGACCGCCACG 
               
               
                   
               
               
                 UCCUCUUUGUUGCUCAGCGCCGCAUCCUGCCCCGCCCUAAGCGCUCUGUCAACUCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGUCCUCGCUCUCGCACCCUGACCGCUGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCC 
               
               
                   
               
               
                 GUCGAGAUCGUCGGCAAGCGUAUCCGCACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACG 
               
               
                   
               
               
                 AGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGCCUACGGCGAGGUUUACCGCCGACUAACCGGCCG 
               
               
                   
               
               
                 CUCUGUUGUCUUCGAGUUCCCCCAGAGCGGUGCCGCCGAGUACUAG 
               
               
                   
               
               
                 SEQ ID NO 220: &gt;XM_001213780.1  Aspergillus terreus  NIH2624 40S ribosomal 
               
               
                 protein S7 (ATEG_04602) mRNA, complete cds 
               
               
                 ATGGCTGCTATCAACAAGATCGCCCACAACTCGCCGTCTCGGCAGAACCCCTCCGAGCTGGAGACCGCGA 
               
               
                   
               
               
                 TCGCCGGTGCTCTGTTCGACCTCGAGAGCAACACCACCGACCTGAAGGCCACCCTCCGCCCCCTTCAGTT 
               
               
                   
               
               
                 CGTGTCTGCTCGTGAGGTTGAGGTCGGCCACGGCAAGAAGGCCGTCATCATCTTCGTCCCTGTCCCTCTC 
               
               
                   
               
               
                 CTCCAGGGCTTCCACAAGATCCAGCAGCGTCTGACCCGTGAGCTCGAGAAGAAGTTCTCCGACCGCCACG 
               
               
                   
               
               
                 TCCTCTTCGTTGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGTCCCCGTTCCCGCACTCTGACGGCCGTCCACGACGCCATCCTCACCGACCTCGTCTACCCC 
               
               
                   
               
               
                 GTCGAGATCGTCGGCAAGCGCATCCGCACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTCGACG 
               
               
                   
               
               
                 AGAAGGAGCGCGGCGGTGTCGACCACCGCCTCGATGCCTACGGCGAGGTCTACCGTCGTCTCACCGGCCG 
               
               
                   
               
               
                 TGCCGTCGTCTTCGAGTTCCCCCAGAGCGGTGCTGCTGACTACTAA 
               
               
                   
               
               
                 SEQ ID NO 221; RNA  Aspergillus terreus  NIH2624 40S ribosomal 
               
               
                 protein S7 (AUEG_04602) mRNA, complete cds 
               
               
                 AUGGCUGCUAUCAACAAGAUCGCCCACAACUCGCCGUCUCGGCAGAACCCCUCCGAGCUGGAGACCGCGA 
               
               
                   
               
               
                 UCGCCGGUGCUCUGUUCGACCUCGAGAGCAACACCACCGACCUGAAGGCCACCCUCCGCCCCCUUCAGUU 
               
               
                   
               
               
                 CGUGUCUGCUCGUGAGGUUGAGGUCGGCCACGGCAAGAAGGCCGUCAUCAUCUUCGUCCCUGUCCCUCUC 
               
               
                   
               
               
                 CUCCAGGGCUUCCACAAGAUCCAGCAGCGUCUGACCCGUGAGCUCGAGAAGAAGUUCUCCGACCGCCACG 
               
               
                   
               
               
                 UCCUCUUCGUUGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAA 
               
               
                   
               
               
                 GCAGAAGCGUCCCCGUUCCCGCACUCUGACGGCCGUCCACGACGCCAUCCUCACCGACCUCGUCUACCCC 
               
               
                   
               
               
                 GUCGAGAUCGUCGGCAAGCGCAUCCGCACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUCGACG 
               
               
                   
               
               
                 AGAAGGAGCGCGGCGGUGUCGACCACCGCCUCGAUGCCUACGGCGAGGUCUACCGUCGUCUCACCGGCCG 
               
               
                   
               
               
                 UGCCGUCGUCUUCGAGUUCCCCCAGAGCGGUGCUGCUGACUACUAA 
               
               
                   
               
               
                 SEQ NO 222:  C. albicans  1899 
               
               
                 CATCACYTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTYGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ NO 223:  C. albicans  1899 
               
               
                 CAUCACYUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUYGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ NO 224  C. albicans  2738 
               
               
                 CATCACYTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTYGCTGTTCACAGAATYTCTG 
               
               
                   
               
               
                 STGAAGAAGCTGCCTAYAAATTGGGTAAAGTCAAGAAAGTYCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ NO 225  C. albicans  2738 
               
               
                 CAUCACYUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUYGCUGUUCACAGAAUYUCUG 
               
               
                   
               
               
                 SUGAAGAAGCUGCCUAYAAAUUGGGUAAAGUCAAGAAAGUYCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ NO 226  C. albicans  1912 
               
               
                 CATCACYTTGGAAGCTACCAACGAACATTTCAGATTAGTCTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTACAAATTGGGTAAAGTCAAGAAAGTCCAATTAGGTAAGAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ NO 227  C. albicans  1912 
               
               
                 CAUCACYUUGGAAGCUACCAACGAACAUUUCAGAUUAGUCUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUACAAAUUGGGUAAAGUCAAGAAAGUCCAAUUAGGUAAGAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ NO 228  C. parapsilosis  6318 
               
               
                 YATTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ NO 229  C. parapsilosis  6318 
               
               
                 YAUUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ NO 230  C. parapsilosis  6395 
               
               
                 CATCACTTTGGAAGCTACYAAYGAACATTTTMGATTGATCTACGATGTYAAAGGTAGATTYGCTGTYCAYAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCCACYTACAAATTGGGTAAAGTTAAGAAAGTCCAATTAGGTAAAAAGGGAATYCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ NO 231:  C. parapsilosis  6395 
               
               
                 CAUCACUUUGGAAGCUACYAAYGAACAUUUUMGAUUGAUCUACGAUGUYAAAGGUAGAUUYGCUGUYCAYAGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCCACYUACAAAUUGGGUAAAGUUAAGAAAGUCCAAUUAGGUAAAAAGGGAAUYCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ NO 232:  C. parapsilosis  96141 
               
               
                 CATTACTTTGGAAGCCACCAACGAACACTTTAGATTGATTTACGATGTTAARGGTAGATTYGCTGTCCACAGAATYTCTG 
               
               
                   
               
               
                 CTGARGAAGCCACCTACAAATTGGGTAAAGTTAAGAAAGTCCAATTAGGTAAAAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGYAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ NO 233:  C. parapsilosis  96141 
               
               
                 CAUUACUUUGGAAGCCACCAACGAACACUUUAGAUUGAUUUACGAUGUUAARGGUAGAUUYGCUGUCCACAGAAUYUCUG 
               
               
                   
               
               
                 CUGARGAAGCCACCUACAAAUUGGGUAAAGUUAAGAAAGUCCAAUUAGGUAAAAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGYAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 234:  C. parapsilosis  96137 
               
               
                 CATTACTTTGGAAGCCACCAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACCATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 235:  C. parapsilosis  96137 
               
               
                 CAUUACUUUGGAAGCCACCAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACCAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 236:  C. parapsilosis  96143rep 
               
               
                 CATCACTTTGGAAGCTACYAAYGAACATTTYAGATTGATCTACGATGTYAAAGGTAGATTYGCTGTYCAYAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCCACYTACAAATTGGGTAAAGTTAAGAAAGTCCAATTAGGTAAAAAGGGAATYCCATACGTTGTCACCCAY 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 237:  C. parapsilosis  96143rep 
               
               
                 CAUCACUUUGGAAGCUACYAAYGAACAUUUYAGAUUGAUCUACGAUGUYAAAGGUAGAUUYGCUGUYCAYAGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCCACYUACAAAUUGGGUAAAGUUAAGAAAGUCCAAUUAGGUAAAAAGGGAAUYCCAUACGUUGUCACCCAY 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 238:  C. parapsilosis  109 
               
               
                 YAYTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 239:  C. parapsilosis  109 
               
               
                 YAYUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 240:  C. parapsilosis  2195 
               
               
                 YATTACYTTGGAAGCYACYAAYGAAAACTTYAGATTGRTYTACGAYGTCAARGGTAGATTYGCTGTCCACMGWATMTCWG 
               
               
                   
               
               
                 MYGAAGAAGCYWCYTACAARTTGGGTAARGTCAAGARRGTCCAATTGGGTAAGAAGGGWRTYCCATACGTTGTCACYSAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 241:  C. parapsilosis  2195 
               
               
                 YAUUACYUUGGAAGCYACYAAYGAAAACUUYAGAUUGRUYUACGAYGUCAARGGUAGAUUYGCUGUCCACMGWAUMUCWG 
               
               
                   
               
               
                 MYGAAGAAGCYWCYUACAARUUGGGUAARGUCAAGARRGUCCAAUUGGGUAAGAAGGGWRUYCCAUACGUUGUCACYSAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 242:  C. parapsilosis  2315 
               
               
                 CATCACTTTGGAAGCTACYAAYGAACATTTYAGATTGATCTACGATGTYAAAGGTAGATTYGCTGTCCACAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCCACYTACAAATTGGGTAAAGTTAAGAAAGTCCAATTAGGTAAAAAGGGAATYCCATACGTTGTCACCCAY 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 243:  C. parapsilosis  2315 
               
               
                 CAUCACUUUGGAAGCUACYAAYGAACAUUUYAGAUUGAUCUACGAUGUYAAAGGUAGAUUYGCUGUCCACAGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCCACYUACAAAUUGGGUAAAGUUAAGAAAGUCCAAUUAGGUAAAAAGGGAAUYCCAUACGUUGUCACCCAY 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 244:  C. krusei  6199 
               
               
                 CATCACTTTAGAWGCAACCAACGAACACTTCAGATTAATCTATGACATCAAGGGTAGATTCGCAATCCACAGAATCACCC 
               
               
                   
               
               
                 CAGAAGAAGCTGCATACAAGTTATGTAAGGTCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCTTATGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 245:  C. krusei  6199 
               
               
                 CAUCACUUUAGAWGCAACCAACGAACACUUCAGAUUAAUCUAUGACAUCAAGGGUAGAUUCGCAAUCCACAGAAUCACCC 
               
               
                   
               
               
                 CAGAAGAAGCUGCAUACAAGUUAUGUAAGGUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCUUAUGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 246:  C. tropicalis  8072 
               
               
                 CATTACCTTGGAAGCTACCAACGAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 247:  C. tropicalis  8072 
               
               
                 CAUUACCUUGGAAGCUACCAACGAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 248:  C. tropicalis  2316 
               
               
                 CATCACTTTRGAWGCWACCAACGAACAYTTCAGATTAATCTACGAYGTCAAGGGTAAATTCGCTGTCCACAGAATCACYG 
               
               
                   
               
               
                 CTGAAGAAGCTGCCTMCAAATTGGTTAARGTMAAGAAAGTCCAATTAGGTAAGARAGGTGTTCCWTACGTTGTTACCCAC 
               
               
                   
               
               
                 GAYGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 249:  C. tropicalis  2316 
               
               
                 CAUCACUUURGAWGCWACCAACGAACAYUUCAGAUUAAUCUACGAYGUCAAGGGUAAAUUCGCUGUCCACAGAAUCACYG 
               
               
                   
               
               
                 CUGAAGAAGCUGCCUMCAAAUUGGUUAARGUMAAGAAAGUCCAAUUAGGUAAGARAGGUGUUCCWUACGUUGUUACCCAC 
               
               
                   
               
               
                 GAYGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 250:  C. dubliniensis  16971 
               
               
                 CATYACYTTRGAAGCTACYAAYGAACATTTCAGATTAGTWTACGATGTTAAAGGTAAATTYGCYGTTCAYAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTKCCTACAAATTGGGTAAAGTYAARAAAGTCCAATTRGGTAARAAAGGTGTTCCATAYGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 251:  C. dubliniensis  16971 
               
               
                 CAUYACYUURGAAGCUACYAAYGAACAUUUCAGAUUAGUWUACGAUGUUAAAGGUAAAUUYGCYGUUCAYGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUKCCUACAAAUUGGGUAAAGUYAARAAAGUCCAAUURGGUAARAAAGGUGUUCCAUAYGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 252:  C. dublininesis  16721 
               
               
                 CATYACYTTRGAAGCTACYAAYGAACATTTCAGATTAGTWTACGATGTTAAAGGTAAATTYGCYGTTCAYAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTKCCTACAAATTGGGTAAAGTYAAGAAAGTCCAATTRGGTAARAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 253:  C. dublininesis  16721 
               
               
                 CAUYACYUURGAAGCUACYAAYGAACAUUUCAGAUUAGUWUACGAUGUUAAAGGUAAAUUYGCYGUUCAYAGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUKCCUACAAAUUGGGUAAAGUYAAGAAAGUCCAAUURGGUAARAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 254:  C. dubliniensis  16197 
               
               
                 CATYACYTTRGAAGCTACYAAYGAACATTTCAGATTAGTWTACGATGTTAAAGGTAAATTYRCYGTTCAYAGAATCTCTG 
               
               
                   
               
               
                 CTGAAGAAGCTKCCTACAAATTGGGTAAAGTYAARAAAGTCCAATTRGGTAARAAAGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 255:  C.dubliniensis  16197 
               
               
                 CAUYACYUURGAAGCUACYAAYGAACAUUUCAGAUUAGUWUACGAUGUUAAAGGUAAAUUYRCYGUUCAYAGAAUCUCUG 
               
               
                   
               
               
                 CUGAAGAAGCUKCCUACAAAUUGGGUAAAGUYAARAAAGUCCAAUURGGUAARAAAGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 256:  C. norvegenesis  2145 
               
               
                 TATCACTTTAGAAGCAACCAACGAAAACTTCAGATTAATCTACGACATCAAGGGTAGATTCGCAATTCACAGAATCACTC 
               
               
                   
               
               
                 CTGAAGAAGCAGCATACAAGTTATGTAAGATCAAGAAGGTCCAATTAGGTAAGAAGGGTATTCCATAYGTTGTTACACAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 257:  C. norvegenesis  2145 
               
               
                 UAUCACUUUAGAAGCAACCAACGAAAACUUCAGAUUAAUCUACGACAUCAAGGGUAGAUUCGCAAUUCACAGAAUCACUC 
               
               
                   
               
               
                 CUGAAGAAGCAGCAUACAAGUUAUGUAAGAUCAAGAAGGUCCAAUUAGGUAAGAAGGGUAUUCCAUAYGUUGUUACACAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 258:  C. guilliermondii  23 
               
               
                 CATCACCTTGGAGGCCACCAACGAGCACTTYAGATTGGTGTACGACGTCAAGGGTAGATTTGCTGTCCACAGAATCACCG 
               
               
                   
               
               
                 CTGAGGAGGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTTCAATTGGGYAAGAGAGGTATTCCATACGTTGTGACCCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 259:  C. guilliermondii  23 
               
               
                 CAUCACCUUGGAGGCCACCAACGAGCACUUYAGAUUGGUGUACGACGUCAAGGGUAGAUUUGCUGUCCACAGAAUCACCG 
               
               
                   
               
               
                 CUGAGGAGGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUUCAAUUGGGYAAGAGAGGUAUUCCAUACGUUGUGACCCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 260:  C. guilliermondii  8167 
               
               
                 ATCACCTTGGAGGCTACCAACGAGCACTTCAGATTGGTGTACGATGTCAAGGGTAGATTTGCTGTCCACAGAATCACCGC 
               
               
                   
               
               
                 TGAAGAGGCTTCCTACAAGTTGGGTAAGGTCAAGAAGGTTCAATTGGGTAAGAGAGGTATTCCATACGTTGTTACCCACG 
               
               
                   
               
               
                 ACGGTAGAACCATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 261:  C. guilliermondii  8167 
               
               
                 AUCACCUUGGAGGCUACCAACGAGCACUUCAGAUUGGUGUACGAUGUCAAGGGUAGAUUUGCUGUCCACAGAAUCACCGC 
               
               
                   
               
               
                 UGAAGAGGCUUCCUACAAGUUGGGUAAGGUCAAGAAGGUUCAAUUGGGUAAGAGAGGUAUUCCAUACGUUGUUACCCACG 
               
               
                   
               
               
                 ACGGUAGAACCAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 262:  C. lusitaniae  64 
               
               
                 CACCTTGGARGCCACCAACGAAAACTTCAGATTGGTGTACGACATCAAGGGTAGATTCACTGTCCACAGAATCACCGCTG 
               
               
                   
               
               
                 ARGAAGGTTCCTACAAGTTGGGTAAGGTCAAGAAGATYGCTTTGGGCAAGAAGGCTATCCCATACGTGGTTACCCACGAY 
               
               
                   
               
               
                 GGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 263:  C. lusitaniae  64 
               
               
                 CACCUUGGARGCCACCAACGAAAACUUCAGAUUGGUGUACGACAUCAAGGGUAGAUUCACUGUCCACAGAAUCACCGCUG 
               
               
                   
               
               
                 ARGAAGGUUCCUACAAGUUGGGUAAGGUCAAGAAGAUYGCUUUGGGCAAGAAGGCUAUCCCAUACGUGGUUACCCACGAY 
               
               
                   
               
               
                 GGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 264:  C. lipolytica  112 
               
               
                 CAGATTGGTGTACGACGTCAAGGGTAGATTCGCCGTGCACAGAATCACCGCCGAGGAGTCCACCTACAAGTTGGCCAAGA 
               
               
                   
               
               
                 TCAAGAAGGTCCAGTTGGGCAAGAAGAGTATCCCCTACGCCGTCACCCACGACGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 265:  C. lipolytica  112 
               
               
                 CAGAUUGGUGUACGACGUCAAGGGUAGAUUCGCCGUGCACAGAAUCACCGCCGAGGAGUCCACCUACAAGUUGGCCAAGA 
               
               
                   
               
               
                 UCAAGAAGGUCCAGUUGGGCAAGAAGAGUAUCCCCUACGCCGUCACCCACGACGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 266:  C. lipolytica  31 
               
               
                 CATCACCTTGGRRGCCACCAACGAAAACTTCAGATTGGTGTACGACATCAAGGGTAGATTCACTGTCCACAGAATCACCG 
               
               
                   
               
               
                 CTGAGGAAGGTTCCTACAAGTTGGGTAAGGTCAAGAAGATYGCTTTGGGCAAGAAGGCTATCCCATACGTGGTTACCCAC 
               
               
                   
               
               
                 GAYGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 267:  C. lipolytica  31 
               
               
                 CAUCACCUUGGRRGCCACCAACGAAAACUUCAGAUUGGUGUACGACAUCAAGGGUAGAUUCACUGUCCACAGAAUCACCG 
               
               
                   
               
               
                 CUGAGGAAGGUUCCUACAAGUUGGGUAAGGUCAAGAAGAUYGCUUUGGGCAAGAAGGCUAUCCCAUACGUGGUUACCCAC 
               
               
                   
               
               
                 GAYGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 268:  C. lipolytica  113 
               
               
                 TTCAGATTGGTGTACGACGTCAAGGGTAGATTCGCCGTGCACAGAATCACCGCCGAGGAGTCCACCTACAAGTTGGCCAA 
               
               
                   
               
               
                 GATCAAGAAGGTCCAGTTGGGCAAGAAGAGTATCCCCTACGCCGTCACCCACGACGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 269:  C. lipolytica  113 
               
               
                 UUCAGAUUGGUGUACGACGUCAAGGGUAGAUUCGCCGUGCACAGAAUCACCGCCGAGGAGUCCACCUACAAGUUGGCCAA 
               
               
                   
               
               
                 GAUCAAGAAGGUCCAGUUGGGCAAGAAGAGUAUCCCCUACGCCGUCACCCACGACGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 270:  C. rugosa  85 
               
               
                 CTTGAGCTACCAACGAAAACTTCASMTTGATCTACGACGTCAAGGGTAGATTTGCCGTCCACAGAATCACCGCTGAAGAA 
               
               
                   
               
               
                 GCTTCGTACAAGTTGGSYAAGGTYAAGTCCGTCCAATTGGGYAAGMGMSKKATYCCTTACGCYGTTACYCACGAYGGTAG 
               
               
                   
               
               
                 AACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 271:  C. rugosa  85 
               
               
                 CUUGAGCUACCAACGAAAACUUCASMUUGAUCUACGACGUCAAGGGUAGAUUUGCCGUCCACAGAAUCACCGCUGAAGAA 
               
               
                   
               
               
                 GCUUCGUACAAGUUGGSYAAGGUYAAGUCCGUCCAAUUGGGYAAGMGMSKKAUYCCUUACGCYGUUACYCACGAYGGUAG 
               
               
                   
               
               
                 AACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 272:  C. rugosa  613 
               
               
                 CCTTGGAAGCTACCAACGAAAACTTCAGATTGATCTACGACGTCAAGGGTAGATTTGCCGTCCACAGAATCACCGCTGAA 
               
               
                   
               
               
                 GAAGCTTCGTACAAGTTGGSYAAGGTYAAGTCCGTCCAATTGGGYAAGMGMSKKATTCCTTACGCYGTTACYCACGAYGG 
               
               
                   
               
               
                 TAGAACYATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 273:  C. rugosa  613 
               
               
                 CCUUGGAAGCUACCAACGAAAACUUCAGAUUGAUCUACGACGUCAAGGGUAGAUUUGCCGUCCACAGAAUCACCGCUGAA 
               
               
                   
               
               
                 GAAGCUUCGUACAAGUUGGSYAAGGUYAAGUCCGUCCAAUUGGGYAAGMGMSKKAUUCCUUACGCYGUUACYCACGAYGG 
               
               
                   
               
               
                 UAGAACYAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 274:  C. rugosa  41 
               
               
                 CATCTCGCTTGAAGCCACCAACGAAAACTTCAGATTGATCTACGACGTCAAGGGTAGATTTGCCGTCCACAGAATCACCG 
               
               
                   
               
               
                 CYGAAGWGGCYTCGTACAAGTTGGSYAAGGTYAAGTCCGTCCAATTGGGYAAGMGMSKKATYCCTTACGCYGTYACYCAC 
               
               
                   
               
               
                 GACGGTAGAACTAYCAGATACCCAG 
               
               
                   
               
               
                 SEQ 275:  C. rugosa  41 
               
               
                 CAUCUCGCUUGAAGCCACCAACGAAAACUUCAGAUUGAUCUACGACGUCAAGGGUAGAUUUGCCGUCCACAGAAUCACCG 
               
               
                   
               
               
                 CYGAAGWGGCYUCGUACAAGUUGGSYAAGGUYAAGUCCGUCCAAUUGGGYAAGMGMSKKAUYCCUUACGCYGUYACYCAC 
               
               
                   
               
               
                 GACGGUAGAACUAYCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 276:  C. rugosa  44 
               
               
                 TCGCTTGAGCCACCAACGAAAACTTCAGATTGATCTACGACGTCAAGGGTAGATTTGCCGTCCACAGAATCACCGCTGAA 
               
               
                   
               
               
                 GAGGCYTCGTACAAGTTGGSYAAGGTYAAGTCCGTCCAATTGGGYAAGMGMSKKATYCCTTACGCYGTYACYCACGACGG 
               
               
                   
               
               
                 TAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 277:  C. rugosa  44 
               
               
                 UCGCUUGAGCCACCAACGAAAACUUCAGAUUGAUCUACGACGUCAAGGGUAGAUUUGCCGUCCACAGAAUCACCGCUGAA 
               
               
                   
               
               
                 GAGGCYUCGUACAAGUUGGSYAAGGUYAAGUCCGUCCAAUUGGGYAAGMGMSKKAUYCCUUACGCYGUYACYCACGACGG 
               
               
                   
               
               
                 UAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 278:  C. rugosa  46 
               
               
                 TCGCTTGAGCCACCAACGAAAACTTCAGATTGATCTACGACGTCAAGGGTAGATTTGCCGTCCACAGAATCACCGCTGAA 
               
               
                   
               
               
                 GAGGCYTCGTACAAGTTGGSYAAGGTYAAGTCCGTCCAATTGGGYAAGMGMSKKATYCCTTACGCYGTYACYCACGACGG 
               
               
                   
               
               
                 TAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 279:  C. rugosa  46 
               
               
                 UCGCUUGAGCCACCAACGAAAACUUCAGAUUGAUCUACGACGUCAAGGGUAGAUUUGCCGUCCACAGAAUCACCGCUGAA 
               
               
                   
               
               
                 GAGGCYUCGUACAAGUUGGSYAAGGUYAAGUCCGUCCAAUUGGGYAAGMGMSKKAUYCCUUACGCYGUYACYCACGACGG 
               
               
                   
               
               
                 UAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 280:  C. famata  1 
               
               
                 CATCACTTTAGAAGCYACCAACGAACACTTCAGATTAATCTAYGAYGTCAAGGGTAGATTCACTGTYCACAGAATCACCG 
               
               
                   
               
               
                 CYGAAGAAGCTTCTTACAAGTTAGCTAAGGTYAAGAAGGTYCAATTAGGTAAGAGWGGTATTCCATACGTTGTYACCCAC 
               
               
                   
               
               
                 GATGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 281:  C. famata  1 
               
               
                 CAUCACUUUAGAAGCYACCAACGAACACUUCAGAUUAAUCUAYGAYGUCAAGGGUAGAUUCACUGUYCACAGAAUCACCG 
               
               
                   
               
               
                 CYGAAGAAGCUUCUUACAAGUUAGCUAAGGUYAAGAAGGUYCAAUUAGGUAAGAGWGGUAUUCCAUACGUUGUYACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 282:  C. famata  2 
               
               
                 CATCACYTTAGAAGCYACCAACGAACACTTCAGATTRATCTATGAYGTCAAGGGTAGATTCACTGTCCACAGAATCACYG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAGTTAGCYAAGGTCAAGAAGGTCCAATTAGGTAAGAGAGGTATTCCATACGYTGTYACWCAC 
               
               
                   
               
               
                 GAYGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 283:  C. famata  2 
               
               
                 CAUCACYUUAGAAGCYACCAACGAACACUUCAGAUURAUCUAUGAYGUCAAGGGUAGAUUCACUGUCCACAGAAUCACYG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAGUUAGCYAAGGUCAAGAAGGUCCAAUUAGGUAAGAGAGGUAUUCCAUACGYUGUYACWCAC 
               
               
                   
               
               
                 GAYGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 284:  C. famata  3 
               
               
                 CATCACTTTAGAAGCYACCAACGAACACTTCAGATTAATCTAYGAYGTCAAGGGTAGATTCACTGTYCACAGAATCACCG 
               
               
                   
               
               
                 CYGAAGAAGCTTCTTACAAGTTAGCTAAGGTYAAGAAGGTYCAATTAGGTAAGAGRGGTATTCCATACGTTGTYACCCAC 
               
               
                   
               
               
                 GATGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 285:  C. famata  3 
               
               
                 CAUCACUUUAGAAGCYACCAACGAACACUUCAGAUUAAUCUAYGAYGUCAAGGGUAGAUUCACUGUYCACAGAAUCACCG 
               
               
                   
               
               
                 CYGAAGAAGCUUCUUACAAGUUAGCUAAGGUYAAGAAGGUYCAAUUAGGUAAGAGRGGUAUUCCAUACGUUGUYACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 286:  C. famata  4 
               
               
                 CATCACYTTAGAAGCYACCAACGAACACTTCAGATTRATCTATGAYGTCAAGGGTAGATTCACTGTCCACAGAATCACYG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAGTTAGCYAAGGTCAAGAAGGTCCAATTAGGTAAGAGAGGTATTCCATAYGYTGTYACWCAC 
               
               
                   
               
               
                 GAYGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 287:  C. famata  4 
               
               
                 CAUCACYUUAGAAGCYACCAACGAACACUUCAGAUURAUCUAUGAYGUCAAGGGUAGAUUCACUGUCCACAGAAUCACYG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAGUUAGCYAAGGUCAAGAAGGUCCAAUUAGGUAAGAGAGGUAUUCCAUAYGYUGUYACWCAC 
               
               
                   
               
               
                 GAYGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 288:  C. famata  5 
               
               
                 CATCACTTTAGAAGCYACCAACGAACACTTCAGATTRATCTATGAYGTCAAGGGTAGATTCACTGTCCACAGAATCACYG 
               
               
                   
               
               
                 CTGAAGAAGCTTCTTACAAGTTAGCYAAGGTCAAGAAGGTCCAATTAGGTAAGAGAGGTATTCCATACGTTGTYACMCAC 
               
               
                   
               
               
                 GAYGGTAGAACTATCAG 
               
               
                   
               
               
                 SEQ 289:  C. famata  5 
               
               
                 CAUCACUUUAGAAGCYACCAACGAACACUUCAGAUURAUCUAUGAYGUCAAGGGUAGAUUCACUGUCCACAGAAUCACYG 
               
               
                   
               
               
                 CUGAAGAAGCUUCUUACAAGUUAGCYAAGGUCAAGAAGGUCCAAUUAGGUAAGAGAGGUAUUCCAUACGUUGUYACMCAC 
               
               
                   
               
               
                 GAYGGUAGAACUAUCAG 
               
               
                   
               
               
                 SEQ 290:  C. haemuloni  52 
               
               
                 CACCTTGGAGGCCACCAACGAGAACTTCAGATTGGTGTACGATGTCAAGGGTAGATTCACTGTCCACAGAATCACCGCTG 
               
               
                   
               
               
                 AGGAGGCTTCCTACAAGCTCGGTAAGGTCARGAAGATCGCTTTGGGTAAGAGAGGTGTTCCATACGTTGTCACCCACGAC 
               
               
                   
               
               
                 GGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 291:  C. haemuloni  52 
               
               
                 CACCUUGGAGGCCACCAACGAGAACUUCAGAUUGGUGUACGAUGUCAAGGGUAGAUUCACUGUCCACAGAAUCACCGCUG 
               
               
                   
               
               
                 AGGAGGCUUCCUACAAGCUCGGUAAGGUCARGAAGAUCGCUUUGGGUAAGAGAGGUGUUCCAUACGUUGUCACCCACGAC 
               
               
                   
               
               
                 GGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 292:  C. haemulonii  53 
               
               
                 CACCTTGGAGGCCACCAACGAGAACTTCAGATTGGTGTACGAYGTCAAGGGTAGATTCACTGTCCACAGAATCACCGCTG 
               
               
                   
               
               
                 AGGAGGCTTCTTACAAGCTCGGTAAGGTCAGAAAGATCGCYTTGGGTAAGAGAGGTATYCCATACGTTGTCACCCACGAC 
               
               
                   
               
               
                 GGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 293:  C. haemulonii  53 
               
               
                 CACCUUGGAGGCCACCAACGAGAACUUCAGAUUGGUGUACGAYGUCAAGGGUAGAUUCACUGUCCACAGAAUCACCGCUG 
               
               
                   
               
               
                 AGGAGGCUUCUUACAAGCUCGGUAAGGUCAGAAAGAUCGCYUUGGGUAAGAGAGGUAUYCCAUACGUUGUCACCCACGAC 
               
               
                   
               
               
                 GGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 294:  C. pulcherrima  36 
               
               
                 GATCACTTTGGAGGCYACCAACGAGAACTTYAGATTGATCTAYGACGTVAAGGGTAGATTYACTGTGCACAGAATCACSR 
               
               
                   
               
               
                 CCGAGGAGGSCTCKTACAAGTTGGGYAAGGTCAGAAAGATCGCCTTGGGYAAGAGAGGYGTKCCTTACGCYGTSACCCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 295:  C. pulcherrima  36 
               
               
                 GAUCACUUUGGAGGCYACCAACGAGAACUUYAGAUUGAUCUAYGACGUVAAGGGUAGAUUYACUGUGCACAGAAUCACSR 
               
               
                   
               
               
                 CCGAGGAGGSCUCKUACAAGUUGGGYAAGGUCAGAAAGAUCGCCUUGGGYAAGAGAGGYGUKCCUUACGCYGUSACCCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 296:  C. pulcherrima  37 
               
               
                 GATCACTTTGGAGGCYACCAACGAGAACTTCAGATTGATCTAYGACGTMAAGGGTAGATTYACTGTGCACAGAATCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCTCKTACAAGTTGGGYAAGGTCAGAAAGATYGCCTTGGGYAAGAGAGGYGTKCCTTACGCYGTVACYCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 297:  C. pulcherrima  37 
               
               
                 GAUCACUUUGGAGGCYACCAACGAGAACUUCAGAUUGAUCUAYGACGUMAAGGGUAGAUUYACUGUGCACAGAAUCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCUCKUACAAGUUGGGYAAGGUCAGAAAGAUYGCCUUGGGYAAGAGAGGYGUKCCUUACGCYGUVACYCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 298:  C. pulcherrima  38 
               
               
                 GATCACTTTGGAGGCYACCAACGAGAACTTYAGATTGATCTAYGACGTVAAGGGTAGATTYACTGTGCACAGAATCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCTCKTACAAGTTGGGYAAGGTCAGAAAGATCGCCTTGGGYAAGAGAGGYGTKCCTTACGCYGTSACYCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 299:  C. pulcherrima  38 
               
               
                 GAUCACUUUGGAGGCYACCAACGAGAACUUYAGAUUGAUCUAYGACGUVAAGGGUAGAUUYACUGUGCACAGAAUCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCUCKUACAAGUUGGGYAAGGUCAGAAAGAUCGCCUUGGGYAAGAGAGGYGUKCCUUACGCYGUSACYCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 300:  C. pulcherrima  39 
               
               
                 GATCACTTTGGAGGCCACCAACRAGAACTTCAGATTGATCTAYGACGTMAAGGGTAGATTCACYGTGCACAGAATCACCG 
               
               
                   
               
               
                 CCGAGGAGGCCTCKTACAAGTTGGGYAAGGTCAGAAAGATCGCCTTGGGYAAGAGAGGYGTKCCTTACGCYGTMACYCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 301:  C. pulcherrima  39 
               
               
                 GAUCACUUUGGAGGCCACCAACRAGAACUUCAGAUUGAUCUAYGACGUMAAGGGUAGAUUCACYGUGCACAGAAUCACCG 
               
               
                   
               
               
                 CCGAGGAGGCCUCKUACAAGUUGGGYAAGGUCAGAAAGAUCGCCUUGGGYAAGAGAGGYGUKCCUUACGCYGUMACYCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 302:  C. pulcherrima  40 
               
               
                 GATCACTTTGGAGGCCACCAACGAGAACTTYAGATTGATCTAYGACGTSAAGGGTAGATTYACTGTGCACAGAATCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCTCKTACAAGTTGGGYAAGGTCAGAAAGATYGCCTTGGGYAAGAGWGGYGTKCCTTACGCYGTSACYCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 303:  C. pulcherrima  40 
               
               
                 GAUCACUUUGGAGGCCACCAACGAGAACUUYAGAUUGAUCUAYGACGUSAAGGGUAGAUUYACUGUGCACAGAAUCACCG 
               
               
                   
               
               
                 CCGAGGAGGSCUCKUACAAGUUGGGYAAGGUCAGAAAGAUYGCCUUGGGYAAGAGWGGYGUKCCUUACGCYGUSACYCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 304:  C. utilis  50 
               
               
                 CTTGGAGGCCACCAACGAGAACTTCAGATTGGTCTACGATGTCAAGGGTAGATTTGCTGTCCACAGAATCACCGATGATG 
               
               
                   
               
               
                 AAGCTTCTTACAAGCTTGCTAAGGTCAAGAAGGTTCAATTGGGTAAGAGAGGTATCCCATACGTTGTTACCCACGACGGT 
               
               
                   
               
               
                 AGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 305:  C. utilis  50 
               
               
                 CUUGGAGGCCACCAACGAGAACUUCAGAUUGGUCUACGAUGUCAAGGGUAGAUUUGCUGUCCACAGAAUCACCGAUGAUG 
               
               
                   
               
               
                 AAGCUUCUUACAAGCUUGCUAAGGUCAAGAAGGUUCAAUUGGGUAAGAGAGGUAUCCCAUACGUUGUUACCCACGACGGU 
               
               
                   
               
               
                 AGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 306:  C. utilis  51 
               
               
                 CTTGGAGGCCACCAACGAGAACTTCAGATTGGTCTACGATGTCAAGGGTAGATTTGCTGTCCACAGAATCACCGATGATG 
               
               
                   
               
               
                 AAGCTTCTTACAAGCTTGCTAAGGTCAAGAAGGTTCARTTGGGTAAGAGAGGTATCCCATACGTTGTTACCCACGACGGT 
               
               
                   
               
               
                 AGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 307:  C. utilis  51 
               
               
                 CUUGGAGGCCACCAACGAGAACUUCAGAUUGGUCUACGAUGUCAAGGGUAGAUUUGCUGUCCACAGAAUCACCGAUGAUG 
               
               
                   
               
               
                 AAGCUUCUUACAAGCUUGCUAAGGUCAAGAAGGUUCARUUGGGUAAGAGAGGUAUCCCAUACGUUGUUACCCACGACGGU 
               
               
                   
               
               
                 AGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 308:  C. kefyr  59 
               
               
                 CACCTTGGACRCTACCAAMGAAAACTTCAGATTGGTCTACGACGTTAAGGGTAGATTCGCTGTCCACCGTATCACCGACG 
               
               
                   
               
               
                 AAGAAGCTTCTTACAAATTGGGTAAGGTCAGAAAGGTCCAACTAGGTAAGAAGGGTATTCCATACGTTGTTACCCACGAC 
               
               
                   
               
               
                 GGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 309:  C. kefyr  59 
               
               
                 CACCUUGGACRCUACCAAMGAAAACUUCAGAUUGGUCUACGACGUUAAGGGUAGAUUCGCUGUCCACCGUAUCACCGACG 
               
               
                   
               
               
                 AAGAAGCUUCUUACAAAUUGGGUAAGGUCAGAAAGGUCCAACUAGGUAAGAAGGGUAUUCCAUACGUUGUUACCCACGAC 
               
               
                   
               
               
                 GGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 310:  C. kefyr  3898 
               
               
                 TGTCACCTTGGACGCTACCAACGAAAACTTCAGATTGGTCTACGACGTTAAGGGTAGATTCGCTGTCCACCGTATCACCG 
               
               
                   
               
               
                 ACGAAGAAGCTTCTTACAAATTGGGTAAGGTCAGAAAGGTCCAACTAGGTAAGAAGGGTATTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GACGGTAGAACYATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 311:  C. kefyr  3898 
               
               
                 UGUCACCUUGGACGCUACCAACGAAAACUUCAGAUUGGUCUACGACGUUAAGGGUAGAUUCGCUGUCCACCGUAUCACCG 
               
               
                   
               
               
                 ACGAAGAAGCUUCUUACAAAUUGGGUAAGGUCAGAAAGGUCCAACUAGGUAAGAAGGGUAUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GACGGUAGAACYAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 312:  C. viswanathii  92 
               
               
                 CATCACCTTGGAAGCCACCAACGAACACTTCAGATTGGTCTACGACGTCAAGGGTAGATTTGCTGTCCACAGAATCTCCG 
               
               
                   
               
               
                 CTGAAGAAGCYTCCTACAAGTTGGGCAAGGTCAAGAAGGTTGCYTTGGGTAAGAAGGGTGTTCCTTACGTTGTCACCCAC 
               
               
                   
               
               
                 GACGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 313:  C. viswanathii  92 
               
               
                 CAUCACCUUGGAAGCCACCAACGAACACUUCAGAUUGGUCUACGACGUCAAGGGUAGAUUUGCUGUCCACAGAAUCUCCG 
               
               
                   
               
               
                 CUGAAGAAGCYUCCUACAAGUUGGGCAAGGUCAAGAAGGUUGCYUUGGGUAAGAAGGGUGUUCCUUACGUUGUCACCCAC 
               
               
                   
               
               
                 GACGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 314:  C. viswanathii  93 
               
               
                 YAYTACTTTGGAAGCCACYAATGAAAACTTTAGATTGATTTACGATGTCAAAGGTAGATTTGCTGTCCACAGAATCTCAG 
               
               
                   
               
               
                 CTGAAGAAGCCACTTACAAATTGGGTAAAGTCAAGAGAGTCCAATTGGGTAAGAAGGGAATCCCATACGTTGTCACCCAC 
               
               
                   
               
               
                 GATGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 315:  C. viswanathii  93 
               
               
                 YAYUACUUUGGAAGCCACYAAUGAAAACUUUAGAUUGAUUUACGAUGUCAAAGGUAGAUUUGCUGUCCACAGAAUCUCAG 
               
               
                   
               
               
                 CUGAAGAAGCCACUUACAAAUUGGGUAAAGUCAAGAGAGUCCAAUUGGGUAAGAAGGGAAUCCCAUACGUUGUCACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 316:  C. zeylanoides  74 
               
               
                 TCTTGAGGCTACCAACGAGCACTTCAGATTGGTGTACGACGTCAAGGGTAGATTCGCCGTGCACAGAATCACCGCCGAGG 
               
               
                   
               
               
                 AGTCCACCTACAAGTTGGCCAAGATCAAGAAGGTCCAGTTGGGCAAGAAGAGTATCCCCTACGCCGTCACCCACGACGGT 
               
               
                   
               
               
                 AGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 317:  C. zeylanoides  74 
               
               
                 UCUUGAGGCUACCAACGAGCACUUCAGAUUGGUGUACGACGUCAAGGGUAGAUUCGCCGUGCACAGAAUCACCGCCGAGG 
               
               
                   
               
               
                 AGUCCACCUACAAGUUGGCCAAGAUCAAGAAGGUCCAGUUGGGCAAGAAGAGUAUCCCCUACGCCGUCACCCACGACGGU 
               
               
                   
               
               
                 AGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 318:  C. zeylanoides  67 
               
               
                 TCTCTCTTGAGCCACCAAYGAGCACTTCAGATTGGTGTAYGACGTMAAGGGTAGATTYGCYGTGCACAGAATCACCGCKG 
               
               
                   
               
               
                 AGGAGTCSAMYTACAAGTTGGCCAARATCAAGAAGGTKCASTTRGGCAAGAARAGCATCCCYTACGCYGTCACCCAYGAY 
               
               
                   
               
               
                 GGYAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 319:  C. zeylanoides  67 
               
               
                 UCUCUCUUGAGCCACCAAYGAGCACUUCAGAUUGGUGUAYGACGUMAAGGGUAGAUUYGCYGUGCACAGAAUCACCGCKG 
               
               
                   
               
               
                 AGGAGUCSAMYUACAAGUUGGCCAARAUCAAGAAGGUKCASUURGGCAAGAARAGCAUCCCYUACGCYGUCACCCAYGAY 
               
               
                   
               
               
                 GGYAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 320:  C. zeylanoides  69 
               
               
                 TCTCTCTTGAGCCACCAAYGAGCACTTCAGATTGGTGTAYGACGTMAAGGGTAGATTYGCYGTGCACAGAATCACCGCSG 
               
               
                   
               
               
                 AGGAGTCSAMYTACAAGTTGGCCAARATCAAGAAGGTKCASTTRGGCAAGAARAGCATCCCYTACGCYGTCACCCAYGAY 
               
               
                   
               
               
                 GGYAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 321:  C. zeylanoides  69 
               
               
                 UCUCUCUUGAGCCACCAAYGAGCACUUCAGAUUGGUGUAYGACGUMAAGGGUAGAUUYGCYGUGCACAGAAUCACCGCSG 
               
               
                   
               
               
                 AGGAGUCSAMYUACAAGUUGGCCAARAUCAAGAAGGUKCASUURGGCAAGAARAGCAUCCCYUACGCYGUCACCCAYGAY 
               
               
                   
               
               
                 GGYAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 322:  C. zeylanoides  68 
               
               
                 TCTCTCTTGAGCCWCCAACGAGCACTTCAGATTGGTGTACGACGTCAAGGGTAGATTCGCCGTGCACAGAATCACCGCCG 
               
               
                   
               
               
                 AGGAGTCCACCTACAAGTTGGCCAAGATCAAGAAGGTCCAGTTGGGCAAGAAGAGTATCCCCTACGCCGTCACCCACGAC 
               
               
                   
               
               
                 GGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 323:  C. zeylanoides  68 
               
               
                 UCUCUCUUGAGCCWCCAACGAGCACUUCAGAUUGGUGUACGACGUCAAGGGUAGAUUCGCCGUGCACAGAAUCACCGCCG 
               
               
                   
               
               
                 AGGAGUCCACCUACAAGUUGGCCAAGAUCAAGAAGGUCCAGUUGGGCAAGAAGAGUAUCCCCUACGCCGUCACCCACGAC 
               
               
                   
               
               
                 GGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 324:  C. zeylanoides  70 
               
               
                 CTACCAACRAACACTTCAGATTGATTTACGATGTTAAAGGTAAATTCGCTGTTCACAGAATTTCTGCTGAAGAAGCTTCT 
               
               
                   
               
               
                 TACAAATTAGGTAAAGTCAAGAAGGTTCAATTAGGTAAAAAAGGTGTTCCATACGTTGTCACCCACGATGGTAGAACTAT 
               
               
                   
               
               
                 CAGATACCCAG 
               
               
                   
               
               
                 SEQ 325:  C. zeylanoides  70 
               
               
                 CUACCAACRAACACUUCAGAUUGAUUUACGAUGUUAAAGGUAAAUUCGCUGUUCACAGAAUUUCUGCUGAAGAAGCUUCU 
               
               
                   
               
               
                 UACAAAUUAGGUAAAGUCAAGAAGGUUCAAUUAGGUAAAAAAGGUGUUCCAUACGUUGUCACCCACGAUGGUAGAACUAU 
               
               
                   
               
               
                 CAGAUACCCAG 
               
               
                   
               
               
                 SEQ 326:  A. fumigatus 2204 
               
               
                 GTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCTC 
               
               
                   
               
               
                 TCGCACCCTGACCGCTGTCCACGACGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGCA 
               
               
                   
               
               
                 CCAAGGAGGACGGCAGCAAGACTCTCAAGGTCGTTCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGCC 
               
               
                   
               
               
                 TACGGCGAGGTTTACCGCCGACTAACCGGCCGCTCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 327:  A. fumigatus 2204 
               
               
                 GUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCUC 
               
               
                   
               
               
                 UCGCACCCUGACCGCUGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGCA 
               
               
                   
               
               
                 CCAAGGAGGACGGCAGCAAGACUCUCAAGGUCGUUCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGCC 
               
               
                   
               
               
                 UACGGCGAGGUUUACCGCCGACUAACCGGCCGCUCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 328:  A. fumigatus 5062 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCTGTCCACGACGCCATCCTCACCGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTTTACCGCCGACTAACCGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 329:  A. fumigatus 5062 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCUGUCCACGACGCCAUCCUCACCGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUUUACCGCCGACUAACCGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 330:  A. fumigatus 133.61 
               
               
                 TGTTGCTCAGCGCCGCATCCTGCCCCGCCCTAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCTGTCCACGACGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTTTACCGCCGACTAACCGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 331:  A. fumigatus 133.61 
               
               
                 UGUUGCUCAGCGCCGCAUCCUGCCCCGCCCUAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCUGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUUUACCGCCGACUAACCGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 332:  A. fumigatus 419.64 
               
               
                 TGTTGCTCAGCGCCGCATCCTGCCCCGCCCTAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCTGTCCACGACGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTTTACCGCCGACTAACCGGCCGCTCTGTTATCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 333:  A. fumigatus 419.64 
               
               
                 UGUUGCUCAGCGCCGCAUCCUGCCCCGCCCUAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCUGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUUUACCGCCGACUAACCGGCCGCUCUGUUAUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 334:  A. terreus 2729 
               
               
                 CGTTGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACGGCCGTCCACGACGCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTCGACGAGAAGGAGCGCGGCGGTGTCGACCACCGCCTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTCTCACCGGCCGTGCCGTCGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 335:  A. terreus 2729 
               
               
                 CGUUGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACGGCCGUCCACGACGCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUCGACGAGAAGGAGCGCGGCGGUGUCGACCACCGCCUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUCUCACCGGCCGUGCCGUCGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 336:  A. flavus 108.30 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCAAGCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACTGCTGTCCACGACGCCATCCTCGGCGACCTGGTCTACCCCGTTGAGATCGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGATGGCAGCAAGACCCTCAAGGTCATCCTGGATGAGAAGGAGCGTGGTGGTGTTGACCACCGTCTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGTTTGACCGGCCGCAACGTCGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 337:  A. flavus 108.30 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCAAGCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACUGCUGUCCACGACGCCAUCCUCGGCGACCUGGUCUACCCCGUUGAGAUCGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGAUGGCAGCAAGACCCUCAAGGUCAUCCUGGAUGAGAAGGAGCGUGGUGGUGUUGACCACCGUCUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGUUUGACCGGCCGCAACGUCGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 338:  A. flavus 117.62 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCAAGCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACTGCTGTCCACGACGCCATCCTCGGCGACCTGGTCTACCCCGTTGAGATCGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCTCAAGGTCATCCTGGATGAGAAGGAGCGTGGTGGTGTTGACCACCGTCTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGTTTGACCGGCCGCAACGTCGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 339:  A. flavus 117.62 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCAAGCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACUGCUGUCCACGACGCCAUCCUCGGCGACCUGGUCUACCCCGUUGAGAUCGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCUCAAGGUCAUCCUGGAUGAGAAGGAGCGUGGUGGUGUUGACCACCGUCUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGUUUGACCGGCCGCAACGUCGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 340:  A. nidulans 5231 
               
               
                 CGTCGCTCAGCGCCGCATCCTCCCCAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGTACCCTCACTGCTGTTCACGATGCCATCCTTGACGACCTCGTCTACCCCGTTGAGATTGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACTCTCAAGGTTATCCTCGACGAGAAGGAGCGTGGTGTTGACCACCACCGCCTCGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTCTGACGGGTCGTGCTGTCGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 341:  A. nidulans 5231 
               
               
                 CGUCGCUCAGCGCCGCAUCCUUCCCAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGUACCCUCACUGCUGUUCACGAUGCCAUCCUUGACGACCUCGUCUACCCCGUUGAGAUUGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACUCUCAAGGUUAUCCUCGACGAGAAGGAGCGUGGUGGUGUUGACCACCGCCUCGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUCUGACGGGUCGUGCUGUCGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 342:  A. nidulans 4190 
               
               
                 CGTCGCTCAGCGCCGCATCCTCCCCAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGTACCCTTACTGCCGTTCACGACGCCATCCTCGACGACCTCGTCTACCCCGTTGAGATTGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTCGACGAGAAGGAGCGTGGTGGTGTTGACCACCGCCTCGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTCTGACGGGTCGTGCTGTCGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 343:  A. nidulans 4190 
               
               
                 CGUCGCUCAGCGCCGCAUCCUCCCCAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGUACCCUUACUGCCGUUCACGACGCCAUCCUCGACGACCUCGUCUACCCCGUUGAGAUUGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUCGACGAGAAGGAGCGUGGUGGUGUUGACCACCGCCUCGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUCUGACGGGUCGUGCUGUCGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 344:  A. nidulans 100.2 
               
               
                 CGTCGCTCAGCGCCGCATCCTCCCCAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGTACCCTTACTGCCGTTCACGACGCCATCCTCGACGACCTCGTCTACCCCGTTGAGATTGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTCGACGAGAAGGAGCGTGGTGGTGTTGACCACCGCCTCGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTCTGACGGGTCGTGCTGTCGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 345:  A. nidulans 100.2 
               
               
                 CGUCGCUCAGCGCCGCAUCCUCCCCAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGUACCCUUACUGCCGUUCACGACGCCAUCCUCGACGACCUCGUCUACCCCGUUGAGAUUGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUCGACGAGAAGGAGCGUGGUGGUGUUGACCACCGCCUCGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUCUGACGGGUCGUGCUGUCGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 346:  A. versicolor  323 
               
               
                 CGTCGCTCAGCGCCGCATCCTTCCCAAGCCCAAGCGCTCCGTCAACTCTCGCACCAACCAGAAGCAGAAGCGCCCTCGTT 
               
               
                   
               
               
                 CTCGCACCCTGACGGCTGTCCACGACTCCATCCTTGACGACCTCGTCTACCCCGTTGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCTCAAGGTCATCCTCGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTCGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTTTGACCGGTCGTGCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 347:  A. versicolor 1323 
               
               
                 CGUCGCUCAGCGCCGCAUCCUUCCCAAGCCCAAGCGCUCCGUCAACUCUCGCACCAACCAGAAGCAGAAGCGCCCUCGUU 
               
               
                   
               
               
                 CUCGCACCCUGACGGCUGUCCACGACUCCAUCCUUGACGACCUCGUCUACCCCGUUGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCUCAAGGUCAUCCUCGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUCGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUUUGACCGGUCGUGCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 348:  A. versicolor 2196 
               
               
                 CGTCGCTCAGCGCCGCATCCTTCCTAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCTCGTT 
               
               
                   
               
               
                 CTCGCACTCTGACGGCTGTCCACGACTCCATCCTTGACGACCTCGTCTACCCCGTTGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCTCAAGGTCATCCTCGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTCGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTTTGACCGGTCGTGCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 349:  A. versicolor 2196 
               
               
                 CGUCGCUCAGCGCCGCAUCCUUCCUAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCUCGUU 
               
               
                   
               
               
                 CUCGCACUCUGACGGCUGUCCACGACUCCAUCCUUGACGACCUCGUCUACCCCGUUGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCUCAAGGUCAUCCUCGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUCGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUUUGACCGGUCGUGCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 350:  A. versicolor 5058 
               
               
                 CGTCGCTCAGCGCCGCATCCTTCCTAAGCCTAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGCACCCTGACGGCCGTCCACGATGCTATCCTTGACGACCTCGTCTACCCCGTTGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCTCAAGATCATCCTCGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTTGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTTTGACTGGTCGTGCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 351:  A. versicolor 5058 
               
               
                 CGUCGCUCAGCGCCGCAUCCUUCCUAAGCCUAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGCACCCUGACGGCCGUCCACGAUGCUAUCCUUGACGACCUCGUCUACCCCGUUGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCUCAAGAUCAUCCUCGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUUGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUUUGACUGGUCGUGCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 352:  A. versicolor 6898 
               
               
                 CGTCGCTCAGCGCCGCATCCTTCCTAAGCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGCACCCTGACGGCCGTCCACGATGCCATCCTTGACGACCTCGTCTACCCCGTTGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCTCAAGATCATCCTCGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTTGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTTTGACTGGTCGTGCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 353:  A. versicolor 6898 
               
               
                 CGUCGCUCAGCGCCGCAUCCUUCCUAAGCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGCACCCUGACGGCCGUCCACGAUGCCAUCCUUGACGACCUCGUCUACCCCGUUGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCUCAAGAUCAUCCUCGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUUGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUUUGACUGGUCGUGCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 354:  A. versicolor 111.32 
               
               
                 CGTTGCTCAGCGCCGCATCCTTCCTAAGCCTAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCCCGTT 
               
               
                   
               
               
                 CCCGCACCCTGACGGCCGTCCACGATGCTATCCTTGACGACCTCGTCTACCCCGTTGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCTCAAGATCATCCTCGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTTGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGTTTGACTGGTCGTGCTGTTGTTTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 355:  A. versicolor 111.32 
               
               
                 CGUUGCUCAGCGCCGCAUCCUUCCUAAGCCUAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCCCGUU 
               
               
                   
               
               
                 CCCGCACCCUGACGGCCGUCCACGAUGCUAUCCUUGACGACCUCGUCUACCCCGUUGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACGCUCAAGAUCAUCCUCGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUUGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGUUUGACUGGUCGUGCUGUUGUUUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 356:  A. clavatus 7944 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CCCGCACCCTGACTGCCGTTCACGACGCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTCGGCAAGCGCACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCGTCCTTGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGTTTAACCGGCCGCTCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 357:  A. clavatus 7944 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CCCGCACCCUGACUGCCGUUCACGACGCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUCGGCAAGCGCACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCGUCCUUGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGUUUAACCGGCCGCUCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 358:  A. clavatus 2391 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCCGTCAACTCCCGCTCCAACCAGAAGCAGAAGCGCCCTCGCT 
               
               
                   
               
               
                 CCCGCACTCTGACCGCTGTTCACGACGCCATCCTCACTGATCTCGTCTTCCCCGTCGAGATCGTCGGCAAGCGCACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTTGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGCTTAACCGGCCGCTCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 359:  A. clavatus 2391 
               
               
                   
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCCGUCAACUCCCGCUCCAACCAGAAGCAGAAGCGCCCUCGCU 
               
               
                   
               
               
                 CCCGCACUCUGACCGCUGUUCACGACGCCAUCCUCACUGAUCUCGUCUUCCCCGUCGAGAUCGUCGGCAAGCGCACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUUGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGCUUAACCGGCCGCUCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 360:  A. candidus 9695 
               
               
                 CGTCGCTCAGCGCCGCATCCTGTCGCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCT 
               
               
                   
               
               
                 CGCGCACTCTGACCGCCGTGCACGACAACATCCTGACCGACCTGGTCTACCCCGTCGAGATCGTCGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCTCAAGGTTATCCTGGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTGGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGACTGACGGGCCGCAACGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 361:  A. candidus 9695 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGUCGCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCU 
               
               
                   
               
               
                 CGCGCACUCUGACCGCCGUGCACGACAACAUCCUGACCGACCUGGUCUACCCCGUCGAGAUCGUCGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCUCAAGGUUAUCCUGGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUGGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGACUGACGGGCCGCAACGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 362:  A. candidus 567.65 
               
               
                 CGTCGCTCAGCGCCGCATCCTGTCGCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCT 
               
               
                   
               
               
                 CGCGCACTCTGACCGCCGTGCACGACAACATCCTGACCGACCTTGTCTACCCCGTCGAGATCGTCGGCAAGCGCGTCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCTCAAGGTTATCCTGGACGAGAAGGAGCGTGGCGGCGTTGACCACCGTCTGGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGACTGACGGGCCGCAACGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 363:  A. candidus 567.65 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGUCGCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCU 
               
               
                   
               
               
                 CGCGCACUCUGACCGCCGUGCACGACAACAUCCUGACCGACCUUGUCUACCCCGUCGAGAUCGUCGGCAAGCGCGUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCUCAAGGUUAUCCUGGACGAGAAGGAGCGUGGCGGCGUUGACCACCGUCUGGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGACUGACGGGCCGCAACGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 364:  A. candidus 225.80 
               
               
                 CGTCGCTCAGCGCCGCATCCTGTCGCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCT 
               
               
                   
               
               
                 CGCGCACTCTGACCGCCGTGCACGACAACATCCTGACCGACCTCGTCTACCCCGTCGAGATCGTCGGCAAGCGCGTCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCTCAAGGTTATCCTGGACGAGAAGGAGCGCGGCGGCGTTGACCACCGCCTGGACGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGACTCACCGGCCGCAACGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 365:  A. candidus 225.80 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGUCGCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGAAGCAGAAGCGCCCCCGCU 
               
               
                   
               
               
                 CGCGCACUCUGACCGCCGUGCACGACAACAUCCUGACCGACCUCGUCUACCCCGUCGAGAUCGUCGGCAAGCGCGUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCCUCAAGGUUAUCCUGGACGAGAAGGAGCGCGGCGGCGUUGACCACCGCCUGGACGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGACUCACCGGCCGCAACGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 366:  A. glaucus 2425 
               
               
                 CGTCGCTCAGCGCCGCATCCTCTCCCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGACCCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CGCGTACTCTGACCGCTGTCCACGACTCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTTGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCATCAAGGTTGTTCTCGACGAGAAGGAGCGCGGTGGTGTTGACCACAGACTTGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCAGACTGACCGGCCGTGCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 367:  A. glaucus 2425 
               
               
                 CGUCGCUCAGCGCCGCAUCCUCUCCCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGACCCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CGCGUACUCUGACCGCUGUCCACGACUCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUUGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCAUCAAGGUUGUUCUCGACGAGAAGGAGCGCGGUGGUGUUGACCACAGACUUGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCAGACUGACCGGCCGUGCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 368:  A. glaucus MA542 
               
               
                 CATCGCTCAGCGCCGCATCCTCTCCCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGACCCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACCGCTGTCCACGACTCCATCCTCACTGACCTCGTCTACCCCGTCGAGATCGTTGGCAAGCGCATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCATCAAGGTTGTTCTCGACGAGAAGGAGCGCGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCAGACTGACCGGCCGTGCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 369:  A. glaucus MA542 
               
               
                 CAUCGCUCAGCGCCGCAUCCUCUCCCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGACCCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACCGCUGUCCACGACUCCAUCCUCACUGACCUCGUCUACCCCGUCGAGAUCGUUGGCAAGCGCAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCAUCAAGGUUGUUCUCGACGAGAAGGAGCGCGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCAGACUGACCGGCCGUGCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 370:  A. glaucus MA5279 
               
               
                 CATCGCTCAGCGCCGCATCCTCTCCCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGACCCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACTGCTGTCCACGACTCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTTGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCATCAAGGTTGTTCTCGACGAGAAGGAGCGCGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCAGACTGACCGGCCGTGCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 371:  A. glaucus MA5279 
               
               
                 CAUCGCUCAGCGCCGCAUCCUCUCCCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGACCCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACUGCUGUCCACGACUCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUUGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACCAUCAAGGUUGUUCUCGACGAGAAGGAGCGCGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCAGACUGACCGGCCGUGCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 372:  A. glaucus 117314 
               
               
                 CGCTCAGCGCCGCATCCTCTCCCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGACCCAGAAGCGTCCCCGTTCCC 
               
               
                   
               
               
                 GCACTCTGACCGCTGTCCACGACTCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTTGGCAAGCGCATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACCATCAAGGTTGTTCTTGACGAGAAGGAGCGCGGTGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTCTACCGCAGACTGACCGGCCGTGCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 373:  A. glaucus 117314 
               
               
                 CGCUCAGCGCCGCAUCCUCUCCCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGACCCAGAAGCGUCCCCGUUCCC 
               
               
                   
               
               
                 GCACUCUGACCGCUGUCCACGACUCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUUGGCAAGCGCAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACCAUCAAGGUUGUUCUUGACGAGAAGGAGCGCGGUGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUCUACCGCAGACUGACCGGCCGUGCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 374:  A. glaucus 297.71 
               
               
                 CGCTCAGCGCCGCATCCTCTCCCGCCCCAAGCGCTCCGTCAACTCGCGCACCAACCAGACCCAGAAGCGTCCCCGTTCCC 
               
               
                   
               
               
                 GCACTCTGACTGCTGTCCACGASTCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTTGGCAAGCGTATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACCATCAAGGTTGTTCTCGACGAGAAGGAGCGCGGTGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTCTACCGCAGACTGACCGGCCGTGCCGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 375:  A. glaucus 297.71 
               
               
                 CGCUCAGCGCCGCAUCCUCUCCCGCCCCAAGCGCUCCGUCAACUCGCGCACCAACCAGACCCAGAAGCGUCCCCGUUCCC 
               
               
                   
               
               
                 GCACUCUGACUGCUGUCCACGASUCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUUGGCAAGCGUAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACCAUCAAGGUUGUUCUCGACGAGAAGGAGCGCGGUGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUCUACCGCAGACUGACCGGCCGUGCCGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 376:  A. niger 124.49 
               
               
                 CGTTGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCCGCCAGCTCTCGTTCCAACCAGAAGCAGAAGCGTCCCCGTT 
               
               
                   
               
               
                 CCCGCACTCTGACTGCTGTCCACGACGCCATCCTCACCGACCTCGTCTACCCCGTCGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCTCCAAGACCCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACCGCCTTGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGTCGGTTGACTGGCCGTGCTGTTGTCTTTGAATTCCCCCAGGG 
               
               
                   
               
               
                 SEQ 377:  A. niger 124.49 
               
               
                 CGUUGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCCGCCAGCUCUCGUUCCAACCAGAAGCAGAAGCGUCCCCGUU 
               
               
                   
               
               
                 CCCGCACUCUGACUGCUGUCCACGACGCCAUCCUCACCGACCUCGUCUACCCCGUCGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCUCCAAGACCCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACCGCCUUGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGUCGGUUGACUGGCCGUGCUGUUGUCUUUGAAUUCCCCCAGGG 
               
               
                   
               
               
                 SEQ 378: Alb1 
               
               
                 5′ attgtctacgatgttaaaggtaaattc 3′ 
               
               
                   
               
               
                 SEQ 379: Alb1 
               
               
                 5′ gaatttacctttaacatcgtagacaat 3′ 
               
               
                   
               
               
                 SEQ 380: Alb2 
               
               
                 5′ agaatttctgctgaagaagctgcct 3′ 
               
               
                   
               
               
                 SEQ 381: Alb2 
               
               
                 5′ aggcagcttcttcagcagaaattct 3′ 
               
               
                   
               
               
                 SEQ 382: Alb3a 
               
               
                 5′ tcagattagtctacgatgttaaaggtaaa3′ 
               
               
                   
               
               
                 SEQ 383: Alb3a 
               
               
                 5′ tttacctttaacatcgtagactaatctga 3′ 
               
               
                   
               
               
                 SEQ 384: Alb3 
               
               
                 5′ tcagattagtctacgatgttaaaggtaaattc 3′ 
               
               
                   
               
               
                 SEQ 385: Alb3 
               
               
                 5′ gaatttacctttaacatcgtagactaatctga 3′ 
               
               
                   
               
               
                 SEQ 386: kru2 
               
               
                 5′ agctgcatacaagttatgtaaggtc 3′ 
               
               
                   
               
               
                 SEQ 387: kru2 
               
               
                 5′ gaccttacataacttgtatgcagct 3′ 
               
               
                   
               
               
                 SEQ 388: Kru1 
               
               
                 5′ tcaccccagaagaagctgcat 3′ 
               
               
                   
               
               
                 SEQ 389: Kru1 
               
               
                 5′ atgcagcttcttctggggtga 3′ 
               
               
                   
               
               
                 SEQ 390: Parap1 
               
               
                 5′ aaagtagatttgcttgccac 3′ 
               
               
                   
               
               
                 SEQ 391: Parap1 
               
               
                 5′ gtggcaagcaaatctacttt 3′ 
               
               
                   
               
               
                 SEQ 392: Parap2 
               
               
                 5′ aagggaatcccatacgttgtca 3′ 
               
               
                   
               
               
                 SEQ 393: Parap2 
               
               
                 5′ tgacaacgtatgggattccctt 3′ 
               
               
                   
               
               
                 SEQ 394: Trop1 
               
               
                 5′ taccaacgaacacttcagattgattta 3′ 
               
               
                   
               
               
                 SEQ 395: Trop1 
               
               
                 5′ taaatcaatctgaagtgttcgttggta 3′ 
               
               
                   
               
               
                 SEQ 396: Trop2 
               
               
                 5′ ttctgctgaagaagcttcttacaa 3′ 
               
               
                   
               
               
                 SEQ 397: Trop2 
               
               
                 5′ ttgtaagaagcttcttcagcagaa 3′ 
               
               
                   
               
               
                 SEQ 398: Trop3 
               
               
                 5′ acagaatttctgctgaagaagcttcttacaa 3′ 
               
               
                   
               
               
                 SEQ 399: Trop3 
               
               
                 5′ ttgtaagaagcttcttcagcagaaattctgt 3′ 
               
               
                   
               
               
                 SEQ 400: Trop4 
               
               
                 5′ cgaacacttcagattgatttacgatgttaaa 3′ 
               
               
                   
               
               
                 SEQ 401: Trop4 
               
               
                 5′ tttaacatcgtaaatcaatctgaagtgttcg 3′ 
               
               
                   
               
               
                 SEQ 402: Trop6 
               
               
                 5′ tttaacatcgtaaatcaatctgaagtgttcg3′ 
               
               
                   
               
               
                 SEQ 403: Trop6 
               
               
                 5′ cgaacacttcagattgatttacgatgttaaa 3′ 
               
               
                   
               
               
                 SEQ 404: Trop9 
               
               
                 5′ ttacctttaacatcgtaaatcaatctgaagtgttcgttggt 3′ 
               
               
                   
               
               
                 SEQ 405: Trop9 
               
               
                 5′ accaacgaacacttcagattgatttacgatgttaaaggtaa 3′ 
               
               
                   
               
               
                 SEQ 406: Glab1 
               
               
                 5′ tatcactgacgaagaagcttc 3′ 
               
               
                   
               
               
                 SEQ 407: Glab1 
               
               
                 5′ gaagcttcttcgtcagtgata 3′ 
               
               
                   
               
               
                 SEQ 408: Glab2 
               
               
                 5′ ttgggtaaggtcaagaaggtccaatt 3′ 
               
               
                   
               
               
                 SEQ 409: Glab2 
               
               
                 5′ aattggaccttcttgaccttacccaa 3′ 
               
               
                   
               
               
                 SEQ 410: Glab3 
               
               
                 5′ tatcactgacgaagaagcttcctacaa 3′ 
               
               
                   
               
               
                 SEQ 411: Glab3 
               
               
                 5′ ttgtaggaagcttcttcgtcagtgata 3′ 
               
               
                   
               
               
                 SEQ 412: Glab 5 
               
               
                 5′ atacgttgtcactgacgatggt 3′ 
               
               
                   
               
               
                 SEQ 413: Glab 5 
               
               
                 5′ accatcgtcagtgacaacgtat 3′ 
               
               
                   
               
               
                 SEQ 414: MycoSEQ AF1F 
               
               
                 5′ GACCGCCACGTCCTCTT 3′ 
               
               
                   
               
               
                 SEQ 415: MycoSEQ AF1R 
               
               
                 5′ CTCTGGGGGAACTCGAA 3′ 
               
               
                   
               
               
                 SEQ 416: MycoSEQ NIG1R 
               
               
                 5′ CCCTGGGGGAATTCAAA 3′ 
               
               
                   
               
               
                 SEQ 417: MycoSEQ NIG1F 
               
               
                 5′ GACCGCCACGTTCTCTT 3′ 
               
               
                   
               
               
                 SEQ 418: AF6 FOW 
               
               
                 5′ AGCAAGACTCTCAAGGTC 3′ 
               
               
                   
               
               
                 SEQ 419: ASP2 
               
               
                 5′ AGGTTTACCGCCGACTAACC 3′ 
               
               
                   
               
               
                 SEQ 420: ASP2 
               
               
                 5′ GGTTAGTCGGCGGTAAACCT 3′ 
               
               
                   
               
               
                 SEQ 421: AFUM1 
               
               
                 5′ CGCTGTCCACGACGCCATCCTCA 3′ 
               
               
                   
               
               
                 SEQ 422: AFUM1 
               
               
                 5′ TGAGGATGGCGTCGTGGACAGCG 3′ 
               
               
                   
               
               
                 SEQ 423: AFUM2 
               
               
                 5′ CCGACTAACCGGCCGCTCTG 3′ 
               
               
                   
               
               
                 SEQ 424: AFUM2 
               
               
                 5′ CAGAGCGGCCGGTTAGTCGG 3′ 
               
               
                   
               
               
                 SEQ 425: ACAN1 
               
               
                 5′ CGTGCACGACAACATCCTGACCGA 3′ 
               
               
                   
               
               
                 SEQ 426: ACAN1 
               
               
                 5′ TCGGTCAGGATGTTGTCGTGCACG 3′ 
               
               
                   
               
               
                 SEQ 427: ACAN2 
               
               
                 5′ CGGCGGCGTTGACCACCGCCTGGAC 3′ 
               
               
                   
               
               
                 SEQ 428: ACAN2 
               
               
                 5′ GTCCAGGCGGTGGTCAACGCCGCCG 3′ 
               
               
                   
               
               
                 SEQ 429: ATERR1 
               
               
                 5′ CGGCGGTGTCGACCACCGCCTC 3′ 
               
               
                   
               
               
                 SEQ 430: ATERR1 
               
               
                 5′ GAGGCGGTGGTCGACACCGCCG 3′ 
               
               
                   
               
               
                 SEQ 431: ATERR2 
               
               
                 5′ CGTCTCACCGGCCGTGCCGTCGTC 3′ 
               
               
                   
               
               
                 SEQ 432: ATERR2 
               
               
                 5′ GACGACGGCACGGCCGGTGAGACG 3′ 
               
               
                   
               
               
                 SEQ 433: AVER1 
               
               
                 5′ CTTGACGACCTCGTCTACCCCGTTG 3′ 
               
               
                   
               
               
                 SEQ 434: AVER1 
               
               
                 5′ CAACGGGGTAGACGAGGTCGTCAAG 3′ 
               
               
                   
               
               
                 SEQ 435: AVER2 
               
               
                 5′ CTACCGTCGTTTGACCGGTCGTGCTGTTG 3′ 
               
               
                   
               
               
                 SEQ 436: AVER2 
               
               
                 5′ CAACAGCACGACCGGTCAAACGACGGTAG 3′ 
               
               
                   
               
               
                 SEQ 437: ANID1 
               
               
                 5′ GTACCCTCACTGCTGTTCACGATGC 3′ 
               
               
                   
               
               
                 SEQ 438: ANID1 
               
               
                 5′ GCATCGTGAACAGCAGTGAGGGTAC 3′ 
               
               
                   
               
               
                 SEQ 439: ANID2 
               
               
                 5′ GTCGTCTGACGGGTCGTGCTGTC 3′ 
               
               
                   
               
               
                 SEQ 440: ANID2 
               
               
                 5′ GACAGCACGACCCGTCAGACGAC 3′ 
               
               
                   
               
               
                 SEQ 441: AFLAV1 
               
               
                 5′ GCCGTTTGACCGGCCGCAACGTCGTC 3′ 
               
               
                   
               
               
                 SEQ 442: AFLAV1 
               
               
                 5′ GACGACGTTGCGGCCGGTCAAACGGC 3′ 
               
               
                   
               
               
                 SEQ 443: ACLAV1 
               
               
                 5′ CGAGATCGTCGGCAAGCGCAC 3′ 
               
               
                   
               
               
                 SEQ 444: ACLAV1 
               
               
                 5′ GTGCGCTTGCCGACGATCTCG 3′ 
               
               
                   
               
               
                 SEQ 445: ACLAV2 
               
               
                 CGGCCGCTCCGTTGTCTTCGAG 3′ 
               
               
                   
               
               
                 SEQ 446: ACLAV2 
               
               
                 5′ CTCGAAGACAACGGAGCGGCCG 3′ 
               
               
                   
               
               
                 SEQ 447: ACLAV3 
               
               
                 5′ CGCCGTTTAACCGGCCGCTCCGTTGTC 3′ 
               
               
                   
               
               
                 SEQ 448: ACLAV3 
               
               
                 5′ GACAACGGAGCGGCCGGTTAAACGGCG 3′ 
               
               
                   
               
               
                 SEQ 449:  S. cerevisiae  33 
               
               
                 CATCACTCTAGATGCCACCAATGAAAACTTCAGATTGGTCTACGATGTCAAGGGTAGATTCGCTGTCCACCGTATCACCG 
               
               
                   
               
               
                 ATGAAGAAGCYTCTTACAARTTGGGTAAGGTCAAGAAGGTYCAATTAGGTAAGAAGGGTGTTCCATACGTTGTTACCCAC 
               
               
                   
               
               
                 GATGGTAGAACTATCAGATACCCAG 
               
               
                   
               
               
                 SEQ 450:  S. cerevisiae  33 
               
               
                 CAUCACUCUAGAUGCCACCAAUGAAAACUUCAGAUUGGUCUACGAUGUCAAGGGUAGAUUCGCUGUCCACCGUAUCACCG 
               
               
                   
               
               
                 AUGAAGAAGCYUCUUACAARUUGGGUAAGGUCAAGAAGGUYCAAUUAGGUAAGAAGGGUGUUCCAUACGUUGUUACCCAC 
               
               
                   
               
               
                 GAUGGUAGAACUAUCAGAUACCCAG 
               
               
                   
               
               
                 SEQ 451:  C. neoformans 114 
               
               
                 GGTGTACGATGTCAAGGGTAGATTCACYSTSCACAGAATCACCGCYGAGGAGKCTWCCTACAAGYTSGSYAAGRTCARGA 
               
               
                   
               
               
                 AGRTCSMKTTGGGYAAGAGRRGTRTYCCMTACGYYGTCASCCACGACGGTAGAACTATCAGATACCCAGA 
               
               
                   
               
               
                 SEQ 452:  C. neoformans 114 
               
               
                 GGUGUACGAUGUCAAGGGUAGAUUCACYSUSCACAGAAUCACCGCYGAGGAGKCUWCCUACAAGYUSGSYAAGRUCARGA 
               
               
                   
               
               
                 AGRUCSMKUUGGGYAAGAGRRGURUYCCMUACGYYGUCASCCACGACGGUAGAACUAUCAGAUACCCAGA 
               
               
                   
               
               
                 SEQ 453:  A. fischeri _131700 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCCGTCCACGACGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTACCCGC 
               
               
                   
               
               
                 ACCAAGGAAGACGGCAGCAAGACTCTCAAGGTCATCCTCGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTCTACCGCCGACTGACCGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 454:  A. fischeri _131700 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCCGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUACCCGC 
               
               
                   
               
               
                 ACCAAGGAAGACGGCAGCAAGACUCUCAAGGUCAUCCUCGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUCUACCGCCGACUGACCGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 455:  A. fischeri _211390 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCTGTCCACGATGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTTTACCGCCGACTAACTGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 456:  A. fischeri _211390 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCUGUCCACGAUGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUUUACCGCCGACUAACUGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 457:  A. fischeri _214525 
               
               
                 CGTCGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGTCCTCGCT 
               
               
                   
               
               
                 CTCGCACCCTGACCGCTGTCCACGATGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGTGGTGTTGACCACAGACTCGATGC 
               
               
                   
               
               
                 CTACGGCGAGGTTTACCGCCGACTAACTGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 458:  A. fischeri _214525 
               
               
                 CGUCGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGUCCUCGCU 
               
               
                   
               
               
                 CUCGCACCCUGACCGCUGUCCACGAUGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGC 
               
               
                   
               
               
                 ACCAAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGUGGUGUUGACCACAGACUCGAUGC 
               
               
                   
               
               
                 CUACGGCGAGGUUUACCGCCGACUAACUGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 459:  N. fischeri _1085 
               
               
                 CGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCCGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCTCGCTCCC 
               
               
                   
               
               
                 GCACCCTGACCGCTGTCCACGACGCCATCCTCAACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTTTACCGCCGACTAACCGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 460:  N. fischeri _1085 
               
               
                 CGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCCGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCUCGCUCCC 
               
               
                   
               
               
                 GCACCCUGACCGCUGUCCACGACGCCAUCCUCAACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUUUACCGCCGACUAACCGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 461:  N. fischeri _14726 
               
               
                 TGCTCAGCGCCGCATCCTGCCCCGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCTCGCTCTC 
               
               
                   
               
               
                 GCACCCTGACCGCTGTCCACGACGCCATCCTCACCGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTCTACCGCCGACTAACCGGCCGCTCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 462:  N. fischeri _14726 
               
               
                 UGCUCAGCGCCGCAUCCUGCCCCGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCUCGCUCUC 
               
               
                   
               
               
                 GCACCCUGACCGCUGUCCACGACGCCAUCCUCACCGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUCUACCGCCGACUAACCGGCCGCUCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 463:  N. fischeri _19426 
               
               
                 TGCTCAGCGCCGCATCCTGCCACGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCTCGCTCTC 
               
               
                   
               
               
                 GCACCCTGACCGCCGTCCACGACGCCATCCTCGACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTCTACCGCCGACTAACCGGCCGTGCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 464:  N. fischeri _19426 
               
               
                 UGCUCAGCGCCGCAUCCUGCCACGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCUCGCUCUC 
               
               
                   
               
               
                 GCACCCUGACCGCCGUCCACGACGCCAUCCUCGACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUCUACCGCCGACUAACCGGCCGUGCUGUUGUCUUCGAGUUCCCCCAGAG 
               
               
                   
               
               
                 SEQ 465:  N. fischeri _20179 
               
               
                 TGCTCAGCGCCGCATCCTGCCACGCCCCAAGCGCTCTGTCAACTCCCGCACCAACCAGAAGCAGAAGCGCCCTCGCTCTC 
               
               
                   
               
               
                 GCACCCTGACCGCCGTCCACGACGCCATCCTCGACGACCTCGTTTACCCCGTCGAGATCGTCGGCAAGCGTATCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACTCTCAAGGTCATCCTGGACGAGAAGGAGCGTGGCGGTGTTGACCACAGACTCGATGCCTA 
               
               
                   
               
               
                 CGGCGAGGTCTACCGCCGACTAACCGGCCGTGCTGTTGTCTTCGAGTTCCCCCAGAG 
               
               
                   
               
               
                 SEQ 466:  N. fischeri _20179 
               
               
                 UGCUCAGCGCCGCAUCCUGCCACGCCCCAAGCGCUCUGUCAACUCCCGCACCAACCAGAAGCAGAAGCGCCCUCGCUCUC 
               
               
                   
               
               
                 GCACCCUGACCGCCGUCCACGACGCCAUCCUCGACGACCUCGUUUACCCCGUCGAGAUCGUCGGCAAGCGUAUCCGCACC 
               
               
                   
               
               
                 AAGGAGGACGGCAGCAAGACUCUCAAGGUCAUCCUGGACGAGAAGGAGCGUGGCGGUGUUGACCACAGACUCGAUGCCUA 
               
               
                   
               
               
                 CGGCGAGGUCUACCGCCGACUAACCGGCCGUGCUGUUGUCUUCGAGUUCCCCCAGAG 
               
             
          
         
       
     
     REFERENCES 
     
         
         “ Stakeholder Insight: Invasive fungal infections ”, Datamonitor, January 2004 
         “ Stakeholder Insight: Sepsis, Under reaction to an overreaction ”, Datamonitor March 2006 
         Atkins S. D. and Clark I. M. (2004) Fungal Molecular Diagnostics: A Mini Review.  J. Appl. Genet.  45, 3-15. 
         Delbrück, S., Sonneborn, A., Gerads, M., Grablowitz, A. H. And Ernst, J. F. (1997). Characterization and regulation of genes encoding ribosomal proteins L39 and S7 of human pathogen  Candida albicans . Yeast. 13, 1199-1210. 
         Synetos, D., Dabeva, M. D. and Warner, J. R. (1992). The yeast ribosomal protein S7 and its genes.  J. Biol. Chem.  267, 3008-3013.