Abstract:
The present invention is directed to an assembled syringe for administering powder medicament in the field of medicine. By using a connecting tube, a solvent bottle containing diluent communicates with a solute bottle containing powder by external force, and the diluent is injected into the solute bottle through the connecting tube under pressure. After the powder is dissolved and mixed uniformly, the mixed solution is injected directly into a patient or added to a transfusion bottle or tube. Both the solvent and solute bottles are packaged into a sleeve to avoid contamination. Buckles on the plunger sleeve are fitted into restricting slots on the sleeve. The fitting of the slots and buckles restricts the position of the syringe, self-locking and controlling the magnitude of force by which the solute bottle is communicated with the solvent bottle, controlling the depth of insertion of the needle into the body, and preventing misoperation or damage during transport, fetching and using.

Description:
RELATED APPLICATIONS 
   This application is a national stage application, pursuant to 35 U.S.C. section 371, of International Application No. PCT/CN2004/000924 filed 10 Aug. 2004, which claims priority to CN 200320109812.7 filed 21 Nov. 2003; CN 200320109813.1 filed 21 Nov. 2003; CN 200420041883.2 filed 9 May 2004; and CN 200420042084.7 filed 23 Jun. 2004. 
   BACKGROUND OF THE INVENTION 
   1. Field of the Invention 
   The present invention is directed to syringes in the field of medicine, especially to an assembled syringe for administering powder medicament. According to the present invention a solvent bottle containing diluent communicates with a solute bottle containing powder via a connecting tube. The diluent is injected into the solute bottle through the connecting tube using pressure. After the powder is dissolved and mixed uniformly with the diluent, the mixed solution is injected directly into a patient or added to a transfusion bottle or a transfusion tube. Both the solvent bottle and the solute bottle are packaged into a sleeve to avoid contamination or cross-infection. Buckles provided on the plunger sleeve are fitted into restricting slots. The fitting of the slots and buckles restricts the syringe position, self-locking and controlling the magnitude of force by which the solute bottle communicates with the solvent bottle. This also allows control of the depth of insertion of the needle into the body, and prevents misoperation or damage during transport, fetching and using. The present invention is a novel design with industrial applicability and can be adapted to generalized use in the industries. 
   2. Description of the Related Technology 
   Conventionally in medical applications, syringes, vials and diluents are separately provided. When a nurse is preparing to inject powder medicament, such as penicillin, into the body of a patient, he/she has to pierce the needle of a syringe into a vial containing diluent, draw out the diluent into the syringe, pierce the needle of the syringe into a different vial containing the powder medicament, inject the diluent from the first vial into the second vial to dissolve the powder, then draw the mixed solution into the syringe again before administering it to the patient or adding it to a transfusion bottle or transfusion tube for bolus intravenous injection. The operation involves several medical components and is complicated. Contamination of the syringe or mishandling of the medicament may result. Such syringes must be handled with great care and skill, which may put a nurse operating the syringe under great stress. 
   A Chinese patent application entitled “Vial Type Pressurized Syringe for Powder Medicament” filed by some of the present inventors discloses a syringe structure that punctures an inner bladder of a vial containing the powder medicament by a needle provided on the front end of a plunger to uniformly mix the powder medicament under pressure with a diluent contained in a solute bottle before injection. This syringe structure is advantageous by its simplified structure but the following defects have been found during its use: 
   1. The inner bladder and the solute bottle are not provided with protective jackets and the inner ends of the inner bladder and the solute bottle are not provided with seal stoppers. The needle is not provided with a sheath. Contamination or cross-infection tends to happen due to poor sealing. 
   2. When a nurse is operating the syringe, it is very difficult for him/her to control the force applied to the plunger and the depth of injection of the needle. 
   3. The distance between the inner bladder and the solute bottle is very short, thus causing problems such as sway or damage due to engagement with each other. There may also be unintended communication during transportation, handling or operation. 
   SUMMARY OF THE INVENTION 
   It is an object of the present invention to provide a syringe for premixing and administering powder medicament with novel design to overcome the drawbacks of existing syringes that are prone to contamination and cross-infection. The syringe according to the present invention is more practical and cost effective with considerable industrial applicability. 
   It is another object of the present invention to provide a syringe for premixing and administering powder medicament with novel design to overcome the problem of existing syringes that are difficult to operate and control. The syringe according to the present invention is easy to operate with shortened traveling distance of the needle, making the force applied to the plunger and injection depth of the needle easy to control. 
   It is yet another object of the present invention to provide a syringe for premixing and administering powder medicament with novel design to overcome the problem of loose fitting between the inner bladder and the solute bottle which can cause damage during transportation and handling by providing a locking configuration. 
   It is still yet another object of the present invention to provide a syringe for premixing and administering powder medicament with novel design to overcome the problem of return flow of the mixed medicament and the returning to the original position of the bracket after moving due to the pressure generated after the bracket has been pulled out. 
   The above and other objects of the present invention and the resolution of the technical problems are achieved by the following technical solutions. A syringe for power medicament premixing according the present invention comprises a plunger, a sleeve, a solvent bottle, a connecting tube, a solute bottle and a syringe needle with two piercing ends, in which the plunger is provided on the upper portion of the sleeve and the solvent bottle. Both the solvent bottle and the solute bottle are packaged in the sleeve, wherein the solvent bottle is provided above the solute bottle. A syringe needle having two piercing ends is connected to the bottom portion of the solute bottle. A hollow connecting tube with two piercing ends is provided between the solvent bottle and the solute bottle. One piercing end of the connecting tube is fixed to a bracket plugged into a bottom opening of the solvent bottle. At least two protrusions are formed on the inner side of the bracket. The protrusions are in contact with the bottom opening of the solvent bottle. The central portion of the solvent bottle and the sealing plug are provided with a guiding recess. The bottom opening of the solute bottle is also provided with a sealing plug made of surgical rubber or innoxious rubber. A guiding recess is provided at the central portion of the sealing plug. A piston is provided inside the solute bottle. One piercing end of the syringe needle with two piercing ends is fixed to a bracket plugged into the bottom opening of the solute bottle. At least two protrusions are formed on the inner side of the bracket. The protrusions are in contact with the bottom opening of the solute bottle. The sealing plug, bracket and the syringe needle with two piercing ends are covered with a protecting jacket. The protrusions can be in any form of a nipple, a fin or a hook. 
   The above and other objects of the present invention may be further achieved by the following technical solutions. 
   Said syringe for powder medicament premixing according to the present invention, in which the solvent bottle is applied with inner pressure and provided inside an inner sleeve. The inner sleeve is inserted into the solute bottle, and both the solute bottle and the inner sleeve are arranged inside the sleeve. The lower end face of the inner sleeve formed with holes is in contact with a piston. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is of normal pressure. A piston is provided on the upper end of the solvent bottle and under the plunger, wherein the solvent bottle is inserted into the solute bottle, or the solute bottle is inserted into the solvent bottle, or the outer diameters of the solvent bottle and the solute bottle are identical and a pushing sleeve is provided on the upper edge of the piston inside the solute bottle. 
   Said syringe for powder medicament premixing according to the present invention, in which the solvent bottle is pressurized internally. Said sleeve is provided with restricting slots. The restricting slots comprise a first restricting slot and a second restricting slot, which are upside-down “L”-shaped and communicate with each other. A plunger sleeve integrated with the plunger is provided with buckles vertical to the plunger sleeve. The buckles are fitted into the first restricting slot or the second restricting slot. Two tongues are arranged on the two sides of the lower edge of the plunger sleeve and symmetrical to the axis thereof. Two slots corresponding to the positions of the tongues are arranged on the two sides of the upper edge of the inner sleeve and symmetrical to the axis thereof. The cross-section of the sleeve is of round shape, square shape, rectangular shape, ellipse shape, triangle shape, pentagon shape, or hexagon shape but with inner round shape, etc. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is pressurized internally. Said sleeve is provided with two restricting slots arranged at the two sides of the sleeve and symmetrical to the axis of the sleeve. The restricting slots comprise a first restricting slot and a second restricting slot, which are upside down “L”-shaped. Two buckles symmetrical to the axis of the plunger sleeve and vertical to the end face of the plunger sleeve are arranged on the plunger sleeve integrated with the plunger and are inserted into the first restricting slot or the second restricting slot respectively. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is under normal pressure. Said sleeve is provided with restricting slots, which comprise two “L”-shaped sections communicating with each other. The plunger sleeve integrated with the plunger is provided with buckles, which are inserted into the shorter portion on the upper end of the restricting slots. A viewing port is longitudinally arranged on the sleeve. The cross-section of the sleeve is of round shape, square shape, rectangular shape, ellipse shape, triangle shape, pentagon shape, or hexagon shape but with inner round shape, etc. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is under normal pressure. Said restricting slots are embedded in the inner wall of the sleeve. The restricting slots comprise two “L”-shaped sections communicating with each other. The cross-section of the sleeve is of round shape, square shape, rectangular shape, ellipse shape, triangle shape, pentagon shape, or hexagon shape, but with inner round shape, etc. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is under normal pressure. Said sleeve is provided with two restricting slots arranged at the two sides of the sleeve and symmetrical to the axis of the sleeve. The restricting slots comprise two “L”-shaped sections communicating with each other. Two buckles are symmetrically arranged on the plunger sleeve that is integrated with the plunger. Said two buckles are inserted into the shorter portion of the upper end of the two restricting slots respectively. The sleeve is provided with two viewing ports arranged symmetrically to the axis of the sleeve in the longitudinal direction. 
   Said syringe for powder medicament premixing according to the present invention, in which the inside of said solvent bottle is under normal pressure. Said sleeve is provided with two restricting slots embedded in the two inner sides of the sleeve and symmetrical to the axis of the sleeve. The restricting slots comprise two “L”-shaped sections communicating with each other. Two buckles symmetrically arranged on the plunger sleeve that is integrated with the plunger. Said two buckles are inserted into the shorter portion of the upper end of the two restricting slots respectively. The sleeve is provided with two viewing ports arranged symmetrically to the axis of the sleeve in the longitudinal direction. 

   
     BRIEF DESCRIPTION OF THE DRAWINGS 
       FIG. 1  is a schematic view of the solvent bottle with internal pressure according to the present invention. 
       FIG. 2  is a schematic view of the restricting slot and the buckle of the solvent bottle with internal pressure according to the present invention. 
       FIG. 3  is a schematic view of the solvent bottle with internal pressure with the buckle at position A according to the present invention. 
       FIG. 4  is a schematic view of the solvent bottle with internal pressure with the buckle at position B according to the present invention. 
       FIG. 5  is a schematic view of the solvent bottle with internal pressure with the buckle at position C according to the present invention. 
       FIG. 6  is a schematic view of the solvent bottle with internal pressure with the bracket fixing the connecting tube in the initial position according to the present invention. 
       FIG. 7  is a schematic view of the solvent bottle with internal pressure with the bracket fixing the two-ended syringe needle in the initial position according to the present invention. 
       FIG. 8  is a schematic view of the solvent bottle with internal pressure with the bracket fixing the connecting tube in buckle position B according to the present invention. 
       FIG. 9  is a schematic view of the solvent bottle with internal pressure with the bracket fixing the two-ended syringe needle in buckle position D according to the present invention. 
       FIG. 10  is a schematic view of the external structure of the solvent bottle with normal pressure according to the present invention. 
       FIG. 11  is a schematic view of the internal structure of the solvent bottle with normal pressure according to the present invention. 
       FIG. 12  is a schematic view of the solute bottle inserted into the solvent bottle with normal pressure according to the present invention. 
       FIG. 13  is a schematic view of the solute bottle having same diameter as the solvent bottle with normal pressure according to the present invention. 
   

   DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
   Advantages and features of the present invention will become apparent from the following detailed descriptions of the invention in conjunction with the accompanying drawings. 
   Embodiment 1 
     FIGS. 10 and 11  show a syringe for premixing and administering powder medicament according to the present invention. The syringe basically comprises a plunger  1 , a cylindrical sleeve  5 , a solvent bottle  8 , a connecting tube  14 , a solute bottle  10  and a syringe needle  16  having two piercing ends. The solvent bottle  8  containing a diluent  18  is not pressurized and is under normal pressure. The plunger  1  is provided above the sleeve  5  and the solvent bottle  8 . Both the solvent bottle  8  and the solute bottle  10  are packaged inside the sleeve  5 . The solvent bottle  8  is positioned on the solute bottle  10  and is partially inserted and slidably fitted into the solute bottle  10 . The lower end of the solute bottle is connected with the syringe needle  16 . 
   Two restricting slots  4  are formed on the sleeve  5  symmetrical to the central axis of the sleeve  5 . The restricting slots  4  comprise two “L”-shaped right angle portions communicating with each other. The longer section of a first “L”-shaped portion of the restricting slots is long enough to allow the needle-like connecting tube  14  to pierce through a sealing plug  12  and a piston  9 . The longer section of the second “L”-shaped portion of the restricting slots facilitates a nurse to control the piercing depth of the needle. The shorter sections of the first and the second “L”-shaped portions of the restricting slots are designed for self-locking, that is, a plunger sleeve  2  integrated with the plunger  1  is provided with two symmetrically arranged buckles  3 , which are inserted into the shorter sections of the “L”-shaped portions of the restricting slots  4  and are fitted with the restricting slots  4  in a slidable fashion to achieve self-locking. The buckles  3  are located inside the shorter section of the upper end of the restricting slot  4  to keep it in a self-locking status before use. A viewing port  6  is longitudinally provided on the sleeve  5  to observe the mixing of the powder with the diluent. The viewing port  6  can be configured longer as shown by the dashed lines in  FIG. 10  to observe the connecting tube  14  piercing through the sealing plug  12  and the piston  9 . 
   A piston  17  is provided inside the solvent bottle  8  at the upper end and is located under the plunger  1 . The hollow connecting tube  14  with two piercing ends is provided between the solvent bottle  8  and the solute bottle  10 . One end of the connection tube  14  is fixed on a bracket  13  located on the lower end of the solvent bottle  8 . Two protrusions  25  are formed on two inner sides of the bracket  13 . Protrusions  25  are in contact with the bottom opening of the solvent bottle  8 . The bottom opening of the solvent bottle  8  and the solute bottle  10  are provided respectively with sealing plugs  12  and  15  made of surgical rubber or innoxious rubber. Guiding recesses  26  and  29  are formed on the central portions of the sealing plugs  12  and  15  respectively. The piston  9  is provided inside the solute bottle  10  and is located under the solvent bottle  8 . One end of the syringe needle  16  is fixed to the bracket  11  plugged into the lower end of the solute bottle  10 . Two protrusions  28  are formed on the two inner sides of the bracket  11 . The protrusions  28  are in contact with the bottom opening of the solute bottle  10 . The protrusions  25  and  28  are in the form of protruding nipples. The protecting jacket  7  covers the sealing plug  15 , the bracket  11  and the syringe needle  16 . 
   When in use, the plunger  1  is rotated to make the buckle  3  locate on the upper end of the restricting slot  4 , then the plunger  1  is pressed by hand until the buckle  3  moves along the restricting slot  4  to the lower end of the first portion, then the solvent bottle  8  is applied with pressure through the plunger sleeve  2 , so that the needle-like connecting tube  14  fixed on the bracket  13  will pierce through the sealing plug  12  and the piston  9  when the connecting tube  14  is moving with the bracket  13 . Now the solvent bottle  8  and the solute bottle  10  are communicated with each other via the connecting tube  14 . The diluent will enter the solute bottle to dissolve and mix the powder medicament uniformly under the pressure inside the solvent bottle  8  generated by pressing the plunger  1 . The protecting jacket  7  is then removed and the syringe needle  16  is injected into the patient, or a transfusion bottle or a transfusion tube. The plunger  1  is rotated again so that the buckles  3  enter the second portion of the restricting slot  4 . Then the plunger  1  is pushed again to make the piston  9  move downwardly so that the mixed medicament is forced into the muscle of a patient or a transfusion bottle or a transfusion tube through the syringe needle  16  to finish a complete operation. Because the syringe needle  16  is fixed to the bracket  11 , the bracket  11  will move upwardly to make the syringe needle  16  pierce through the sealing plug  15  of the solute bottle  10  when the syringe needle  16  is injected into the patient or the transfusion bottle. Thus the mixed medicament may enter a human body or a transfusion bottle or tube. 
   The solvent bottle  8  and the solute bottle  10  are integrated inside the sleeve  5  to form an assembly. The assembly can be used only once and should be discarded after use. In fact it is a self-destructive syringe. It is very safe and the problem of cross-contamination can be avoided. 
   Embodiment 2 
   The inside of the solute bottle  10  is under normal pressure. The restricting slot  4  is fitted into the inner wall of the sleeve  5 . The shape of the cross section of the sleeve  5  is of round shape, rectangle shape, square shape, ellipse shape, triangle shape, pentagon shape, or hexagon shape but with inner round shape. Said protrusions  25  and protrusions  28  are three protruding fins or hooks. Other configurations are similar to that of embodiment 1. 
   Embodiment 3 
   As shown in  FIGS. 10 and 12 , the inside of the solvent bottle  8  is under normal pressure, in which the solute bottle  10  is inserted into the solvent bottle  8 . Said protrusions  25  and protrusions  28  are each of five numbers. Other configurations are similar to those of embodiment 1. 
   Embodiment 4 
   As shown in  FIGS. 10 and 13 , the inside of the solute bottle  10  is under normal pressure, in which the solvent bottle  8  and the solute bottle  10  have the same outer diameter. A pushing sleeve  30  is provided on the upper edge of the piston  9  of the solute bottle  10 . Said protrusions  28  and protrusions  25  are each of three numbers and are in a shape of protruding rings. Other configurations are similar to those of embodiment 1. 
   Embodiment 5 
   As shown in  FIG. 1 , this embodiment is characterized in that the inside of the solvent bottle  8  is applied with pressure. The solvent bottle  8  is inserted into an inner sleeve  19  and is able to move along the inner sleeve  19 . Both the solute bottle  10  and the inner sleeve  19  are provided inside the sleeve  5 . The lower end face of the inner sleeve  19  is provided with a hole  27  and is in contact with the piston  9 . The syringe comprises a plunger, a sleeve, a solvent bottle  8 , a connecting tube  14 , a solute bottle  10  and a syringe needle  16  with two piercing ends, in which the plunger  1  is provided on the upper portion of the sleeve  5  and the solvent bottle  8 . Both the solvent bottle  8 , which is provided above the solute bottle  10 , and the solute bottle  10  are packaged in the sleeve  5 . The syringe needle  16  having two piercing ends is connected to the bottom portion of the solute bottle  10 . The connecting tube  14  with two piercing ends is provided between the solvent bottle  8  and the solute bottle  10 . One piercing end of the connecting tube  14  is fixed to a bracket  13  plugged into a bottom opening of the solvent bottle  8 . As shown in  FIG. 6 , three protrusions  25  are formed on the inner side of the bracket  13 . The protrusions  25  are in contact with the bottom opening of the solvent bottle  8 . As shown in  FIGS. 1 ,  6  and  8 , the bottom opening of the solvent bottle  8  is provided with a sealing plug  12  made of surgical rubber or innoxious rubber. The central portion of the sealing plug  12  is provided with a guiding recess  26 . As shown in  FIGS. 1 ,  7  and  9 , the bottom opening of the solute bottle  10  is provided with a sealing plug  15  made of surgical rubber or innoxious rubber. The central portion of the sealing plug  15  is provided with a guiding recess  29 . A piston  9  is contained inside the solute bottle  10 . As shown in  FIG. 1 , one piercing end of the syringe needle  16  is fixed to a bracket  11  plugged into the bottom opening of the solute bottle  10 . As shown in  FIGS. 7 and 9 , the inner side of the bracket  11  is provided with three protrusions  28 , which are in contact with the bottom opening of the solute bottle  10 . The sealing plug  15 , the bracket  11  and the syringe needle  16  with two piercing ends are covered with a protecting jacket  7 . The protrusions  25  and  28  can be protruding rings. Any configuration that allows for moving along the bottle opening and being locked with the step formed outside the bottle opening are acceptable. 
   As shown in  FIGS. 1 and 2 , two restricting slots  4  are symmetrically arranged at the two sides of sleeve  5  symmetrical to the central axis of the sleeve  5 . The restricting slots  4  comprise a first restricting slot  21  and a second restricting slot  23  which are an upside down “L”-shape and communicate with each other. The plunger sleeve  2  integrated with the plunger  1  is provided with two buckles  3  fitted into and moving along the first restricting slot  21  and the second restricting slot  23  respectively. The buckles  3  are arranged vertical to the circumferential end face of the plunger sleeve and symmetrical to the axis of the plunger sleeve  2 . 
   As shown in  FIGS. 3 ,  4  and  5 , two tongues  24  are arranged on the two sides of the lower edge of the plunger sleeve  2  and symmetrical to the axis thereof. Two slots corresponding to the positions of the tongues  24  are arranged on the two sides of the upper edge of the plunger sleeve  2  and symmetrical to the axis thereof. The tongues  24  are inserted into the slots  22  respectively. The cross-section of the sleeve is of round shape. 
   During the preparation of the present embodiment, the solute bottle  10  contained with powder medicament  20  and the solvent bottle  8  contained with diluent  18  are packaged into the sleeve  5  in advance. In the initial state, the buckle  3  is located on the upper end of the first restricting slot  21 , i.e. position A, as shown in  FIG. 2  and  FIG. 3 . 
   When performing an injection, push the plunger  1  slightly to make the buckle  3  rotate into the first restricting slot  21 . Then push the plunger  1  to make the solvent bottle  8  move along the inner sleeve  19  by pushing the plunger sleeve  2  until the buckle  3  reaches the end of the first restricting slot, i.e. position B. At this time, the tongue  24  is inserted into the slot  22  of the inner sleeve  19 , as shown in  FIG. 4 . During this process, due to the effect of pressure, the connecting tube  14  having two piercing ends will pierce through the piston  9  and the sealing plug  12  so that solvent bottle  8  is communicated with the solute bottle  10 . The diluent  18  inside the solvent bottle  8  will be automatically injected into the solute bottle  10  through the connecting tube  14  by the effect of inner pressure to dissolve powder medicament  20 . At the same time, the bracket  13  moves along the bottom opening of the solvent bottle  8  until its end face is in contact with the sealing plug  12 , as shown in  FIG. 8 . During this process, the inner sleeve  19  and the piston  9  move relative to each other and the syringe needle  16  having two piercing ends does not pierce through the sealing plug  15  yet. 
   After the above process, the plunger  1  is pulled up and rotated to make the buckle  3  reach the upper end of the second restricting slot  23  through the connecting portion between the first and the second restricting slots  21  and  23 , i.e. position C. During this operation, the tongue  24  is detached from the slot  22  and the tongue  24  is moved to the upper edge of the slot  22 . At the same time, because the plunger  1  is pulled up and the solvent bottle  8  and the bracket  13  are moved upwardly, the lower end of the connecting tube  14  is drawn out from the piston  9  to disconnect the communication between the solvent bottle  8  and the solute bottle  10  to avoid backflow of liquid medicament due to overpressure inside the solute bottle  10 . 
   The next step is to inject the solution into a human body, a transfusion bottle or a transfusion tube. When the syringe needle  16  is injected into a human body or a transfusion bottle or tube, the counterforce is strong enough to make the bracket  11  slip along the bottom opening of the solute bottle until the end face of the bracket  11  is in contact with the sealing plug  15 , as shown in  FIG. 9 . At this time, the syringe needle  16  has pierced through the sealing plug  15  and the buckle  3  moves along the second restricting slot  23  and down to the bottom end thereof, i.e. position D. By the force applied on the upper edge of the inner sleeve  19  by the tongue  24  of the plunger sleeve  2 , the end face of the inner sleeve  19  is pressed against the piston  9  to make the liquid medicament inject into the human body or the transfusion bottle or tube via the syringe needle  16 , thus to complete the process of injection. 
   Because protrusions  25  and  28  are arranged inside the brackets  13  and  11 , when the end faces of the brackets  13  and  11  are in contact with the sealing plugs  12  and  15  respectively, the protrusions  25  and  28  are positioned to the step at the bottom opening of the solvent bottle  8  and the solute bottle  10  and are locked thereto; therefore the brackets  13  and  11  will not move back to their original positions when the plunger  1  is pulled up or when the syringe needle is drawn out from the human body, ensuring the proper operation and self-destruction for one-time use of the syringe according to the present invention. 
   The present invention has apparent advantages and benefits. It can be known from the above description that the present invention does not have the defects of the existing syringe. The structure of the present invention is more robust and variable for use. The present invention has the following advantages: 
   1. The syringe for medicament powder premixing according to the present invention integrates the solute bottle contained with medicament powder to the syringe needle with two piercing ends. The structure is simple and allows for easy operation, time saving, improved work efficiency, reduced intensity of work, and significantly lowered cost. At the same time, a nurse operating the syringe according to the present invention can be released from stress because misoperation and mistakes can be avoided. 
   2. The syringe for medicament powder premixing according to the present invention has a relatively simple structure and low additional production cost because it can be achieved by slightly changing the structure of the existing syringe. It is worthwhile comparing the added production cost with its great benefit. Therefore it has great industrial applicability. 
   3. The syringe for medicament powder premixing according to the present invention is safer in design. By fitting the restricting slots provided on the sleeve with the buckles provided on the plunger sleeve, it is has both position-limiting and locking functions. Thus, it is easy to control the force applied to the plunger when the bottles are communicating and to manage the depth of injection. The solute bottle and the solvent bottle are fixed to avoid loosening by engaging the buckles on the sleeve with the restricting slots on the plunger sleeve. Therefore, misoperation or damage during transportation and handling can be avoided. The syringe according to the present invention is more practical and meets the requirements of the normal syringe products. 
   Both the solute bottle and the solvent bottle of the syringe for medicament powder premixing according to the present invention are packaged inside the sleeve with a sealing plug and protecting jacket. The medicament powder and the diluent of predetermined dosage are contained in advance during production of the syringe. Therefore contamination and cross-infection can be avoided. The whole syringe is in an aseptic package and will not be in contact with air during operation. The syringe according to the present invention is designed to be used only once and then discarded. 
   The syringe for medicament powder premixing according to the present invention is provided with slots on both the plunger sleeve and the inner sleeve, and with a sliding construction of the bracket along the opening of the bottle. When the connecting tube is pulled out after the solvent bottle and the solute bottle have been connected, such construction can ensure that the medicament inside the solute bottle will not flow back and the bracket will not return to the original position after moving, so that such construction has a self-destruction function and can be used only once. 
   Having thus described several embodiments of this invention, it is to be appreciated that various alterations, modifications, and improvements will readily occur to those skilled in the art. Such alterations, modifications, and improvements are intended to be part of this disclosure, and are intended to be within the spirit and scope of the invention. Accordingly, the foregoing description and drawings are by way of example only.