Abstract:
The present disclosure relates to fluid delivery devices for supplying a fluid, e.g., a flush medium, to a medical device, e.g., a vascular access device, inexpensively. The fluid delivery device includes a collapsible body defining a fluid reservoir and a connector for securing the fluid delivery device to the medical device. The collapsible body can include a bellows or pleated structure. In addition, structure including levers or plungers can be provided to collapse the body.

Description:
TECHNICAL FIELD 
       [0001]    The present disclosure relates to fluid delivery devices and, more particularly, to fluid delivery devices for delivering a fluids medium to a medical device, e.g., vascular access device. 
       BACKGROUND 
       [0002]    Fluid delivery devices for delivering fluid to a medical device for a variety of reasons are well known. For example, syringes are often used to deliver a variety of fluids to a medical vascular access device to provide medication or flush solutions to the vascular access device. Typically, a syringe is disposable and includes a syringe body, a syringe plunger and a sealing member supported on the plunger. The syringe assembly is unnecessarily complex and expensive to manufacture. 
       SUMMARY 
       [0003]    In one aspect, a fluid delivery device includes a body defining a fluid reservoir and a fluid outlet. A connector includes structure to connect the fluid delivery device to a medical device. The body includes one or more pleats and is collapsible to dispense fluid from the fluid reservoir through the fluid outlet. 
         [0004]    In some embodiments, the fluid delivery device includes a flange supported on one end of the body. 
         [0005]    In certain embodiments, the fluid delivery device includes a finger loop supported on the other end of the body opposite the flange. 
         [0006]    In some embodiments, each of the one or more pleats contains a predetermined volume of fluid. 
         [0007]    In certain embodiments, the body defines a plurality of recesses to facilitate gripping of the body. 
         [0008]    In some embodiments, the plurality of recesses includes recesses formed at each end of the body. 
         [0009]    In certain embodiments, the fluid delivery device includes a housing configured to receive the body. 
         [0010]    In some embodiments, the housing defines a cutout dimensioned to receive a clinician&#39;s finger to facilitate compression of the body. 
         [0011]    In certain embodiments, the connector includes spikes positioned to puncture the body. 
         [0012]    In some embodiments, the housing includes markings to identify the volume of fluid dispensed from the reservoir. 
         [0013]    In certain embodiments, the fluid delivery device includes a disc supported on the body within the housing. The disc can have one or more teeth which engage notches on the housing to lock the body in one of a plurality of positions. 
         [0014]    In another aspect, the fluid delivery device includes a collapsible body defining a fluid reservoir, a connector including structure to connect the collapsible body to a medical device, and a plurality of levers pivotally attached to the collapsible body. The levers are movable in relation to each other to move the collapsible body from an expanded position to a collapsed position. 
         [0015]    In some embodiments, a catch is configured to hold the levers in a position to retain the body in the collapsed position. 
         [0016]    In certain embodiments, the fluid delivery device includes a latching mechanism including a first arm extending from one of the plurality of levers having at least one tooth and a second arm extending from another one of the plurality of levers including a plurality of notches. The at least one tooth is advanceable over the notches to progressively lock the levers in relation to each other to prevent expansion of the collapsible body. 
         [0017]    In another aspect, the fluid delivery device includes a collapsible body defining a fluid reservoir, a connector including structure to connect the collapsible body to a medical device, and a clip positioned about the collapsible body. The clip is movable along the collapsible body towards the connector to dispense fluid from the fluid reservoir. 
         [0018]    In some embodiments, the clip is slidable along the collapsible body. 
         [0019]    In certain embodiments, the collapsible body includes an elongated neck portion and the clip is slidably disposed about the elongated neck portion. The clip can be configured to expand outwardly when the collapsible body is compressed to allow fluid to be dispensed from the fluid reservoir and return to an unexpanded state after compression to prevent reflux into the fluid reservoir. 
         [0020]    In yet another aspect, the fluid delivery device includes a collapsible body defining a fluid reservoir, a plunger, and a housing including a connector configured to engage a medical device. The housing is dimensioned to receive the collapsible body and accept the plunger and includes a puncturing port that is configured to puncture the collapsible body when the plunger is advanced to compress the collapsible body. 
         [0021]    In some embodiments, the plunger includes markings to indicate the amount of fluid dispensed from the fluid reservoir. 
         [0022]    In yet another aspect, the fluid delivery device includes a deformable body defining a fluid reservoir, an airbag surrounding the deformable body, and a connector configured to connect the fluid delivery device to a medical device, wherein the airbag can be selectively inflated to dispense fluid from the deformable body. 
     
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         [0023]      FIG. 1A  is a side cross-sectional view of a fluid delivery device in an expanded state. 
           [0024]      FIG. 1B  is a side perspective view of the fluid delivery device of  FIG. 1A . 
           [0025]      FIG. 1C  is a side perspective view of the fluid delivery device of  FIG. 1A  in collapsed state. 
           [0026]      FIG. 2A  is a side cross-sectional view of another embodiment of the fluid delivery device in an expanded state. 
           [0027]      FIG. 2B  is a side cross-sectional view of the fluid delivery device of  FIG. 2A  in the collapsed state. 
           [0028]      FIG. 3  is a side cross-sectional view of another embodiment of the fluid delivery device. 
           [0029]      FIG. 4  is side cross-sectional view of another embodiment of the fluid delivery device in an expanded state. 
           [0030]      FIG. 5  is a front view of another embodiment of the fluid delivery device. 
           [0031]      FIG. 6  is a cross-sectional view of the fluid delivery device of  FIG. 5 . 
           [0032]      FIG. 7  is a front view of another embodiment of the fluid delivery device. 
           [0033]      FIG. 8  is a front view of another embodiment of the fluid delivery device. 
           [0034]      FIG. 9  is a front view of another embodiment of the fluid delivery device. 
           [0035]      FIG. 10  is a cross-sectional view of another embodiment of the fluid delivery device. 
           [0036]      FIG. 11  is a front view of another embodiment of the fluid delivery device. 
           [0037]      FIG. 12  is a cross-sectional view of another embodiment of the fluid delivery device. 
           [0038]      FIG. 13  is a side view of another embodiment of the fluid delivery device. 
           [0039]      FIG. 14  is a cross-sectional view of another embodiment of the fluid delivery device. 
           [0040]      FIG. 15A  is a front perspective view of another embodiment of the fluid delivery device. 
           [0041]      FIG. 15B  is a front perspective view of the fluid delivery device of  FIG. 15A  with parts separated. 
           [0042]      FIG. 15C  is a cross-sectional view of the fluid delivery device of  FIG. 15A . 
           [0043]      FIG. 16  is a front view of another embodiment of the fluid delivery device. 
           [0044]      FIG. 17  is a front view of another embodiment of the fluid delivery device. 
           [0045]      FIG. 18A  is a front perspective view of another embodiment of the fluid delivery device. 
           [0046]      FIG. 18B  is a cross-sectional view of the fluid delivery device of  FIG. 18A . 
           [0047]      FIG. 18C  is a cross-sectional view of the fluid delivery device of  FIG. 18B  including a plunger. 
           [0048]      FIG. 19  is a cross-sectional view of another embodiment of the fluid delivery device. 
       
    
    
     DETAILED DESCRIPTION OF EMBODIMENTS 
       [0049]    Embodiments of the presently disclosed fluid delivery device will now be described in detail with reference to the drawings wherein like reference numerals designate identical or corresponding elements in each of the several views. In this description, the term “proximal” is generally used to refer to the portion of the device that is closer to a clinician, while the term “distal” is generally used to refer to the portion of the device that is farther from the clinician. 
         [0050]    Many of the containers or fluid delivery devices herein are described as including a collapsible body. As used herein, the collapsible body may be formed of both resilient and non-resilient materials, including but not limited to, polyolefins such as polyethylene and polypropylene, fluorinated polyolefins such as polytetrafluoroethylene and perfluoroalkoxy, fluoroelastomers, polyamides such as nylon, polyesters, acrylic polymers, vinyl halide polymers such as polyvinyl chloride, and copolymers and combinations thereof. In addition, the containers described herein may be formed using any of a variety of known processes or combinations thereof, including injection molding and blow molding. 
         [0051]    As used herein, the term connector includes any known structure for connecting the delivery device to another medical device including luer connectors, screw threads, bayonet type couplings and other known connecting structure. Each connector defines a fluid outlet for dispensing a fluid. 
         [0052]      FIG. 1A  is a side cross-sectional view and  FIGS. 1B-1C  are perspective views of an embodiment of the presently disclosed fluid delivery device shown generally as  100 . Delivery device  100  includes a body  104  that defines a fluid reservoir  101  and includes a connector  103 . The connector  103  defines a fluid outlet  103   a.  The body  104  includes one or more pleats or bellows  105  that can collapse to dispense the fluid contents of the fluid reservoir  101  from a fluid outlet  106  or be expanded to aspirate fluid into the reservoir  101 . Each bellow  105  may be dimensioned to contain a predetermined volume of liquid so as to provide a visual indication of the amount of fluid contained in the fluid reservoir  101  and the amount of fluid dispensed from the fluid reservoir  101 . For example, each bellow  105  may define a volume of 1 mL of fluid. Delivery device  100  may further include a finger loop  107  and a grip flange  109  for grasping the delivery device  100  so that the fluid reservoir  101  may be compressed to dispense fluid from within the fluid reservoir  101 . Finger loop  107  and/or grip flange  109  may be integrally formed with body  104 , or, in the alternative, may be connected to body  104  by, for example, screw threads. 
         [0053]      FIGS. 2A and 2B  are side, cross-sectional views of another embodiment of the delivery device, shown generally as  200 . Delivery device  200  includes a body  204  that defines a fluid reservoir  201  and further includes connector  203  defining a fluid outlet  206 . The connector  203  is supported adjacent to a distal end of body  204 . Two or more levers  205  are pivotally mounted to the distal end of body  203  via hinges  207 . The levers  205  are pivotable towards each other about hinges  207  to forcibly collapse the body  204  and dispense the fluid contents of the fluid reservoir  201 . In one embodiment, the levers  205  are substantially rigid and can be made of any suitable rigid material. Alternatively, levers  205  may be formed from any material capable of compressing body  204  to dispense the liquid within reservoir  201 . In another embodiment, the levers  205  are pivotally supported at the proximal end of body  204  by hinges  205 . The hinges  205  may be mechanical or living hinges. In one embodiment, the body  204  is formed from a collapsible non-resilient material including plastics, polymers or the like. Alternatively, resilient, collapsible materials may also be used to form the body  204 . 
         [0054]    The body  204  of the delivery device  200  may be squeezed using levers  205  from a first expanded position, as shown in  FIG. 2A , to a second collapsed position, as shown in  FIG. 2B . The fluid reservoir  201  may contain a predetermined amount of fluid that corresponds to a single dose of a medication or flushing liquid. A catch  209  may be provided on one lever  205  which is positioned to engage the other lever  205  to hold the levers  205  in the collapsed position after a predetermined dose of fluid has been dispensed to prevent the body  204  from expanding and generating reflux into the fluid reservoir  201 . 
         [0055]      FIG. 3  is a side, cross-sectional view of another embodiment of the delivery device, shown generally as  300 . Delivery device  300  includes a substantially rigid body  304  that defines a fluid reservoir  301  and a connector  303  defining a fluid outlet  306 . The body  304  is attached to a refill container  307  which defines a receptacle  307   a.  The body  304  and/or the refill container  307  may be marked with graduations or markings to identify the fluid volume contained within the body  304  and/or container  307 . Refill container  307  may be formed of any suitable material which may be a rigid material or a deformable or collapsible material such as a plastic fluid filled bag. The receptacle  307   a  of refill container  307  communicates with the reservoir  301  of body  304  via an aspiration port  308  and a check valve  309 . Check valve  309  is configured to only permit flow from the receptacle  307   a  into the reservoir  301 . In one embodiment, a plunger  305  may be pushed distally within reservoir  301  to dispense fluid from the fluid reservoir  301 . The check valve  309  prevents fluid flow into the refill container  307  from the reservoir  301 . In addition, the plunger  305  may be pulled proximally to open the check valve  309  to aspirate fluid from the receptacle  307   a  of refill container  307  into the fluid reservoir  301  through aspiration port  308 . In some embodiments, the plunger  305  may be designed to automatically retract to refill the fluid reservoir  301  using any suitable means including, but not limited to, a spring or other biasing device. Further, the area proximal of the plunger  305  may be sealed to allow a negative pressure to build proximally of the plunger  305  as the plunger  305  is pushed distally so that when the plunger  305  is no longer being forced distally, the negative pressure created proximally of the plunger  305  pulls the plunger  305  back in the proximal direction. In one embodiment, the container  307  can be upended to dump fluid from receptacle  307   a  into reservoir  301  through aspiration port  306 . 
         [0056]      FIG. 4  is a side, cross-sectional view of an embodiment of the delivery device, shown generally as  400 . Delivery device  400  includes a collapsible body  404  that defines a fluid reservoir  401  and includes a connector  403 . Two or more levers  405  are pivotally secured to body  404  adjacent luer  403 . The levers  405  are movable toward each other to forcibly compress and collapse the body  404  to dispense the fluid contents of the fluid reservoir  401 . The levers  405  may be made of any suitable rigid material. The hinges  421  may be mechanical or living hinges, and are shown in  FIG. 4  as a living hinge. 
         [0057]    Levers  405  include a latching mechanism comprising a first arm  407   a  having at least one tooth  419  that interfaces with notches  417  that are disposed on second arm  407   b.  Each notch  417  may be designed to correspond to a predetermined amount of fluid being dispensed out of the delivery device  400 . For example, each notch may correspond to 1 mL of dispensed fluid. Delivery device  400  may further include finger loops  409  for gripping levers  405  and a cap  413  for sealing or covering connector  403 . The delivery device  400  can also include a member, such as one or more tethers  423 , that attach the outside of the body  404  to an inner surface of the levers  405  such that when the levers  405  are pulled apart, the body  404  and fluid reservoir  401  defined therein will expand to allow fluid to be drawn into the fluid reservoir  401 . 
         [0058]    In use, the levers  405  are pushed together to dispense fluid from reservoir  401 . As this occurs, the tooth  419  of the latching mechanism is advanced over the notches  417  to progressively lock the levers  405  to different degrees of closure. Thus, the latching mechanism prevents body  404  from expanding to prevent reflux into reservoir  401 . As discussed above, body  401  may be formed from a collapsible resilient or non-resilient material. Latching mechanism prevents reflux caused by the inherent ability of a resilient material to return the body  401  to its non-deformed configuration. 
         [0059]      FIG. 5  illustrates an embodiment of the delivery device, shown generally as  500 . Delivery device  500  includes a collapsible body  504  that defines a fluid reservoir  501  and a connector  503  formed integrally w/ith body  504 . The body  504  is comprised of a flexible plastic bag that may be compressed, rolled from an end in tooth paste dispenser style, or otherwise pressurized to dispense fluid from reservoir  501 . The connector  503  may be sealed with a pull tab seal  505  that can be removed when it is desired to use the delivery device  500 . The body  504  may have markings  507  to indicate the amount of fluid contained in the fluid reservoir  501 . 
         [0060]      FIG. 6  shows a side, cross-sectional view of an embodiment of a delivery device  600 , similar to the embodiment of  FIG. 5 , including a collapsible body  604  that defines a fluid reservoir  601 , a connector  603  and a seal  605  that can be removed when it is desired to use the delivery device  600 . The connector  603  defines a fluid outlet  606 .  FIG. 6  is similar to  FIG. 5  except that connector  603  of body  604  is a separate member which is threadably attached to body  604 . 
         [0061]      FIG. 7  illustrates an embodiment of a delivery device  700  having a body  704  that defines a fluid reservoir  701 , a connector  703  and a seal  705  that can be removed when it is desired to use the delivery device  700 . The embodiment of  FIG. 7  is similar to the embodiment of  FIG. 5  except that the body  704  is elongated is formed from a squeeze-pop type bag. The bag edges of body  704  may be sealed together using RF energy. 
         [0062]      FIG. 8  illustrates an embodiment of the delivery device, shown generally as  800 . Delivery device  800  includes a collapsible body  804  that defines a fluid reservoir  801  and a connector  803 . The body  804  is comprised of a flexible plastic bag that may be compressed, rolled from an end in tooth paste dispenser style, or otherwise pressurized to dispense fluid. The connector  803  may be sealed with a pull tab seal  805  that can be removed when it is desired to use the delivery device. The body may have markings  807  to indicate the amount of fluid contained in the fluid reservoir  801 . The delivery device  800  may further comprise a clip  809  which is positioned about body  804 . The clip  809  may be removed from body  804  to disperse fluid from reservoir  801 , slid down along body  804  to disperse fluid, or slid upward about body  804  to check the body  804  for patency. The clip  809  may be of any suitable size or shape and may, alternately, roll along or roll up the body  804 . For example, the clip  809  may comprise two rollers that sandwich the body  804  under a bias. The rollers may be configured to rotate as the clip  809  is pushed or pulled over the body  804 . 
         [0063]      FIG. 9  illustrates another embodiment of the delivery device, shown generally as  900 . Delivery device  900  includes a collapsible body  904  that defines a fluid reservoir  901  with an elongated neck portion  909  and a connector  903 . The body  904  is comprised of a flexible plastic bag that may be compressed by hand. The body  904  may have markings  907  to indicate the amount of fluid contained in the fluid reservoir  901 . The delivery device  900  may further comprise a clip  905  disposed on the elongated neck portion  909  of body  904 . The clip  905  may be configured to expand outwardly when body  904  is compressed to allow fluid to be dispensed from the fluid reservoir  901  and, thereafter, automatically close to prevent reflux into the fluid reservoir  901 . 
         [0064]      FIG. 10  is a cross-sectional view of another embodiment of the delivery device, shown generally as  1000 . Delivery device  1000  includes a collapsible body  1004  that defines a fluid reservoir  1001  and includes a connector  1003 . As shown in  FIG. 10 , the connector  1003  is welded into the body  1004 . The body  1004  defines a mustard pack that may be compressed or, rolled from an end in tooth paste dispenser style to dispense fluid. The delivery device  1000  has a seal portion  1005  that covers connector  1003 . The seal portion  1005  may be notched at  1107  to allow for tearing of the seal portion  1005  so that the connector  1003  may be exposed and fluid may be dispensed from the device  1000 . 
         [0065]      FIG. 11  is a side view of another embodiment of the delivery device shown generally as  1100 . Delivery device  1100  includes a collapsible, semi-rigid body  1104  that defines a fluid reservoir  1101  attached to a connector  1103  which defines a fluid outlet. The body  1104  may include at least one section comprising one or more bellows or pleats  1105  and a section  1107  defining recesses  1107   a  for gripping. The body  1104  can be gripped by positioning a clinician&#39;s fingers into recesses  1107   a  to compress the bellows  1105  and dispense fluid from reservoir  1101 . As described above, each bellow  1105  may contain to a predetermined volume of dispensed liquid, e.g. 1 mL. 
         [0066]      FIG. 12  is a cross-sectional view of an embodiment of the delivery device, shown generally as  1200 . Delivery device  1200  includes a collapsible body  1204  that defines a fluid reservoir  1201  and a housing  1209  that includes a connector  1203 . The collapsible body  1204  may comprise a fluid filled bag. The housing  1209  may include a puncturing port  1205  that is configured to puncture the body  1204  when the body  1204  is pushed against the puncturing port  1205  with a requisite or predetermined force to dispense the contents of the fluid reservoir  1201 . The housing  1209  is configured to accept a plunger  1211  such that the plunger  1211  can be selectively advanced to compress the body  1204  in the housing  1209  against the puncturing port  1205  to puncture the body  1204 , and to selectively force fluid out of the fluid reservoir  1201  after puncture. The plunger  1211  may have markings  1207  that indicate the amount of fluid dispensed from the fluid reservoir  1201  as the plunger  1211  is advanced into housing  1209 . The plunger  1211  may be removably or permanently slidably attached to the housing  1209 . If the plunger  1211  is removable, then the body  1204  that defines the fluid reservoir  1201  may be replaceable and the device  1200  may be reusable. 
         [0067]      FIG. 13  is a side view of an embodiment of the delivery device, shown generally as  1300 . Delivery device  1300  includes a rigid body  1304  that is dimensioned to receive a collapsible fluid reservoir  1301  and supports a connector  1303 . A plunger  1305  may be slidably disposed within the rigid body  1304  such that the plunger  1305  directly contacts one end of the fluid reservoir  1301 . As the plunger  1305  is advanced within rigid body  1304 , the fluid reservoir  1301  is collapsed to force the fluid out through connector  1303 . The plunger  1305  may be mechanically linked to lever  1307 , such as by a pawl-ratchet type mechanism, such that a discrete advancement of lever  1307  advances the plunger  1305  distally toward connector  1303  a predetermined distance. Each discrete advancement of the lever  1307  may create a noticeable click that corresponds to a predetermined volume of fluid to be dispensed. The rigid body  1304  may have markings indicative of the volume of fluid being dispensed. 
         [0068]      FIG. 14  is a side, cross-sectional view of an embodiment of the delivery device shown generally as  1400 . Delivery device  1400  includes a deformable body  1404  that defines a fluid reservoir  1401  and includes a connector  1403 . The body  1404  is comprised of a semi-rigid flexible plastic container that may be compressed in a manner similar to a plastic squeeze bottle to dispense fluid. The connector  1403  may be sealed with a pull tab seal or cap as described above that can be removed when it is desired to use the delivery device. The body  1404  may have markings to indicate the amount of fluid contained in the fluid reservoir  1401 . 
         [0069]      FIG. 15A  is a perspective view,  FIG. 15B  is an exploded view, and  FIG. 15C  is a cross-sectional view of an embodiment of the delivery device shown generally as  1500 . Delivery device  1500  includes a collapsible body  1504  that defines a fluid reservoir, a housing  1509  configured to hold the body  1504 , and a connector  1503  disposed on a distal end of the housing  1509 . The connector  1503  may be integrally formed with housing  1509 , or releasably attachable thereto. As shown, the body  1504  includes one or more bellows  1505  as described herein. The body  1504  is removably positioned within housing  1509  such that the device  1500  may be reusable. Alternatively, the body  1504  may also be permanently attached to the housing  1509  via any suitable method. The connector  1503  may include one or more spikes  1515  that puncture the body  1504  and enter into the fluid reservoir  1501  when the body  1504  is pushed up against the spikes  1515  during compression of body  1504  in the housing  1509  to dispense fluid from body  1504 . 
         [0070]    The housing  1509  has a cutout  1511  dimensioned to receive a finger or thumb to provide access to body  1504  and facilitate compression of body  1504  to dispense fluid from the fluid reservoir  1501 . The housing  1509  may have markings  1507  that correspond to the amount of fluid that is in the fluid reservoir  1501 . The delivery device  1500  may also include a locking feature wherein the body  1504  supports a disc  1506  ( FIG. 15C ) having one or more teeth  1513  that communicate with one or more notches  1517  ( FIG. 15C ) formed on an inner wall of housing  1509  to lock the body  1504  in a plurality of positions as fluid is dispensed from reservoir  1504 . By locking the body  1504  in compressed positions, reflux into body  1504  can be prevented. Each notch  1517  may correspond to a predetermined amount of fluid to be dispensed, such as, for example 1 mL. 
         [0071]      FIG. 16  is a side view of an embodiment of the delivery device, shown generally as  1600 . Delivery device  1600  includes a deformable body  1604  that defines a fluid reservoir  1601  and includes a connector  1603 . The body  1604  may be a flexible bag or semi-rigid flexible container that may be compressed as described herein. The delivery device  1600  may include rigid members  1605  disposed against the body  1604 . The rigid members  1605  may be squeezed together to dispense fluid from the fluid reservoir  1601 . 
         [0072]    In one embodiment, the rigid members  1605  are strapped together using one or more locking members  1607 . The locking members  1607  may be in the form of cable ties which include a band  1608  having notches  1609  and a receiving portion  1611  defining an opening (not shown). The band  1608  extends through the opening in receiving portion  1611  such that as the notches  1609  are pulled through receiving portion  1611 , the receiving portion  1611  prevents reverse motion of the band  1608 . By preventing reverse motion of band  1608  in relation to receiving portion  1611  expansion of fluid reservoir  1601  and reflux of fluid into the fluid reservoir  1604  are prevented. Each notch  1609  may correspond to a predetermined amount of dispensed fluid, such as 1 mL. The locking members  1607  may have markings to indicate the amount of fluid contained in or dispensed from the fluid reservoir  1601 . 
         [0073]    Device  1600  may further include a stop mechanism  1613  including a first member  1615 , a second member  1619 , and a stop  1617 . First member  1615  and second member  1619  may be attached to the body  1604  or rigid member  1605 . As shown, stop  1617  may be slidably attached to second member  1619  and movable to a desired fixed position that corresponds to a predetermined amount of total fluid to be dispensed by device  1600 . As the fluid reservoir  1601  is dispensed, stop  1617  will contact first member  1615  and prevent further dispensing of fluid. 
         [0074]      FIG. 17  is a side view of another embodiment of the delivery device, shown generally as  1700 . Delivery device  1700  includes a deformable body  1704  that defines a fluid reservoir  1701  and includes a connector  1703  defining a fluid outlet. The body  1704  may be a semi-rigid flexible plastic container or a flexible bag that may be compressed as described herein. Device  1700  further includes an airbag  1707  surrounding the body  1704  such that the airbag  1707  may be selectively inflated to effect dispensing of fluid from the fluid reservoir  1701 . The airbag  1707  may include check valve  1709  that allows air to selectively enter the airbag  1707  but prevents air from exiting the airbag  1707 . Airbag  1707  may also have a release valve (not shown) to selectively expel air therefrom. Similar to the embodiment of  FIG. 16 , the delivery device  1700  may include rigid members  1705  disposed against the body  1704  and strapped together as described above. Rigid members  1705  may be moved together to increase pressure within airbag  1707  and dispense fluid from body  1704 . 
         [0075]      FIG. 18A  is a perspective view and  FIGS. 18B and 18C  are cross-sectional views of another embodiment of the delivery device shown generally as  1800 . Delivery device  1800  includes a collapsible body  1804  that defines a fluid reservoir  1801 , a housing  1805  configured to hold body  1804 , and a connector  1803 . The connector  1803  may form part of the housing  1805 , or be attachable thereto. Referring to  FIG. 18A , the body  1804  is shown in a pre-blow-molded state. Referring to  FIG. 18B and 18C , the body  1804  is shown after blow molding and/or filling with fluid. The body  1804  may be provided as a cartridge which can be removably attached to housing  1805  via any suitable method including, but not limited to, a screw fit or snap fit. The body  1804  may thus be replaceable and the device  1800  may be reusable. Alternatively, the body  1804  may also be permanently attached to the housing  1805  via any suitable method. 
         [0076]    As shown in  FIGS. 18A-C , the housing  1805  includes two or more arms  1807  that form a partial boundary for the body  1804 . Arms  1807  form a track for a plunger  1813  (shown in  FIG. 18C ) to slidably interact therewith to compress the body  1804  and dispense fluid from the fluid reservoir  1801 . The delivery device  1800  may also include a locking feature wherein one or more of the arms  1807  include one or more notches  1809  that communicate with one or more teeth  1811  on a plunger  1813  to progressively lock the position of the plunger  1813  in relation to the housing  1809  in progressively more advanced states. The locking feature prevents proximal movement of plunger  1813  as plunger  1813  is advanced to compress the fluid reservoir  1801  to prevent expansion of the fluid reservoir  1801  which may result in reflux of fluid into the fluid reservoir  1801 . As described with respect to previous embodiments, each notch  1809  may correspond to a predetermined amount of fluid to be dispensed, such as, for example 1 mL, allowing the clinician to control the amount of fluid dispensed from the fluid reservoir  1801 . Plunger  1813  may have markings thereon that correspond to the volume of fluid contained in the fluid reservoir  1801 . Alternatively or in conjunction therewith, the housing  1809  may also have markings to determine the amount of dispensed fluid based on the position of plunger  1813  in relation to the housing  1805 . 
         [0077]      FIG. 19  is a cross-sectional view of an embodiment of a system  1900  and method for filling a body  1904  that defines a fluid reservoir  1901 . Body  1904  includes a filling port  1903 . The system  1900  includes a fill tube  1906  and seal clamps  1902 . The fill tube  1906  may be inserted into filling port  1903  as the reservoir  1901  is held in place by seal clamps  1902  such that the reservoir  1901  can be filled with fill tube  1906 . To prevent bubbles or air pockets, the reservoir  1901  may be filled until overflow fluid  1908  leaks from filling port  1903 . Thereafter, the fill tube  1906  may be removed from filling port  1903 , and filling port  1903  may be sealed using seal clamps  1902  or using any suitable sealing method, including melting, capping, gluing, heat sealing etc. 
         [0078]    Persons skilled in the art will understand that the devices and methods specifically described herein and illustrated in the accompanying drawings are non-limiting exemplary embodiments. It is envisioned that the elements and features illustrated or described in connection with one exemplary embodiment may be combined with the elements and features of another without departing from the scope of the present disclosure. As well, one skilled in the art will appreciate further features and advantages of the disclosure based on the above-described embodiments. Accordingly, the disclosure is not to be limited by what has been particularly shown and described, except as indicated by the appended claims.