Abstract:
A capsule type medical device to conduct an operation in an internal organic portion of a body, is provided with a capsule body to move in the internal organic portion; and an operating member incorporated in the capsule body and to conduct the operation in the internal organic portion. The capsule body includes a bellow section formed on a peripheral surface of the capsule body such that the bellow section stretches or contracts in a longitudinal direction of the capsule body.

Description:
[0001]     This application is based on Japanese Patent Application No. 2005-312493 filed on Oct. 27, 2005, No. 2005-331304 filed on Nov. 16, 2005, and No. 2005-364557 filed on Dec. 19, 2005, in Japanese Patent Office, the entire content of which is hereby incorporated by reference.  
       BACKGROUND OF THE INVENTION  
       [0002]     The present invention relates to a capsule type medical device for image picking-up in the organs, when mainly, a person takes down, and it moves in a predetermined organ.  
         [0003]     Conventionally, in order to inspect the internal organs, a tubular endoscopic apparatus which has an image pick-up lens and image pick-up element at the leading edge and is inserted from the mouth or anus, is well known. Because in this endoscopic apparatus, while the inspection of the internal organs is carried out, the tubular member is continued to be inserted from the outside to the internal organs, the discomfort feeling or pain is not small.  
         [0004]     In order to decrease the such a load of tested subject, recently, the capsule type medical device which the tested subject can take down a single item is developed. The capsule type medical device houses a micro image pick-up apparatus and is structured such that the picked-up image is transmitted to external devices by the radio, and after a predetermined organ is image picked-up, it is discharged from the anus naturally.  
         [0005]     Relating to this capsule type medical device, many patent journals are disclosed.  
         [0006]     For example, the first capsule whose outer shape is small and the second capsule whose outer shape is large are connected by a tube, and when takes down from the first capsule which is small, there is a capsule type medical device which can be taken down without any pain (refer to Patent Document 1).  
         [0007]     Further, there is small sized photographic apparatus in which the capsule type medical device is structured by the capsule unit housing a camera part, the capsule unit housing an LED for illumination, and the capsule unit housing a communication part, and after the tested subject takes down 3 kinds of capsule units one by one, when they are automatically connected and integrated, and the tested subject can easily takes down them (refer to Patent Document 2).  
         [0008]     Further, there is the capsule type medical device in which a camera providing respectively, for example, a telescopic lens and a wide lens at both ends, is independently provided, and its photographic direction is changed by being rotated in the body, (refer to Patent Document 3).  
         [0009]     Further, there is the capsule type medical device in which a spiral protrusion is provided on its outer peripheral surface, and when it is rotated in the rotating magnetic field, the propelling speed is enlarged, and it can be smoothly propelled along the tubular path (refer to Patent Document 4).  
         [0010]     Further, there is the capsule type medical device in which, when the spiral protrusion is provided on its outer peripheral surface and it is rotated in the rotating magnetic field, it can be introduced to the object part (refer to Patent Document 5).  
         [0011]     Other than that, there is the capsule type medical device in which the medicine housed in the inside can be injected in the body (refer to Patent Document 6).  
         [0012]     (Patent Document 1) Tokkai No. 2003-136387  
         [0013]     (Patent Document 2) Tokkai No. 2004-329292  
         [0014]     (Patent Document 3) Tokkai No. 2004-344655  
         [0015]     (Patent Document 4) Tokkai No. 2005-52502  
         [0016]     (Patent Document 5) Tokkai No. 2003-275170  
         [0017]     (Patent Document 6) Tokkai No. 2005-185567  
         [0018]     The capsule type medical device written in Patent Documents 1, 2 at least provides with the image pick-up lens for image picking-up organs, the image pick-up element which image forms the picked-up image and photoelectric converts it, LED which illuminates the organs to be picked-up at the time of image pick-up, image processing part for conducting a predetermined image processing on the photoelectric converted image, transmission part for transmitting outside the image of the image processing part, and receiving part for receiving the signal such as the image pick-up start from the outside, and sends the receives relating to the position or posture in the body.  
         [0019]     Further, the capsule type medical device announced by the manufacturers is formed in the size of, for example, about diameter 10 mm, length 25 mm.  
         [0020]     The capsule type medical device is naturally conveyed by the fibrillation in the organs in the human body shown in  FIG. 1 , however, the small bowel is narrow, and has many curved paths, and there is no security that this size capsule can surely pass the curved paths such as the small bowel. For example, in a part like a hair pin curve such as A part of the small bowel, depending on the largeness or length of the capsule type medical device, as shown in A part enlarged view of  FIG. 2 , the pass of the capsaule type medical apparatus becomes difficult.  
         [0021]     For a time, when the capsule type medical device is caught in the curved par t on the way, it is necessary that the tubular member like as the conventional endoscope is inserted into the organs and the catching of the capsule type medical device is corrected, or takes out is, and to the tested subject, new discomfort feeling or pain is added.  
       SUMMARY OF THE INVENTION  
       [0022]     In view of such a problem, the present invention is attained, and the first object is to provide a capsule type medical device which is structured bendably in the length direction and the risk which is caught when it passes the narrow bending part such as the small bowel is decreased.  
         [0023]     Further, when the capsule type medical device image picks up in the organs whose inner diameter is small such as the small bowel, the distance between the capsule type medical device and the inner wall of the organs, that is, the subject distance is not so much changed. However, when the capsule type medical device image picks-up in the organs whose inner diameter is large such as the stomach or the large bowel, the subject distance is changed by the position of the capsule type medical device. Accordingly, it is desirable that focus position can be adjusted corresponding to subject distance.  
         [0024]     Further, depending on the object of the image pick-up, because there is a case of partially enlarged and image picked-up or case of image pick-up of the large range, it is desirable that the angle of view to be image picked-up can be changed. Relating to this point, in the capsule type medical device written In Patent Document 3, by the camera respectively provided at both ends, for example, the image pick-up of telephoto and the image pick-up of the wide can be conducted. However, when these two cameras are provided, the capsule type medical device becomes large, and the tested subject hardly takes down, and it becomes difficult that it passes the organs which is narrow and has many bending parts like as the small bowel. Further, it cost much.  
         [0025]     In view of such a problem, the present invention is attained, and the second object of the present invention is to propose the capsule type medical device by which the distance between lenses is changed when it is a simple structure and a part of the image pick-up lens is moved in the optical axis direction, and the subject distance to be focused or the focal length can be changed.  
         [0026]     Further, when the image of the organs of the tested subject picked-up by the capsule type medical device is observed by the inspection doctor by an external device, there is a case where an anxious disease is discovered at the periphery of the picked-up image. In this case, as described above, the lens may be changed to the wide lens and image picked-up so that the wide range is picked-up, however, there is a problem that the image becomes small and it becomes difficult to be observed.  
         [0027]     Further, in the capsule type medical device written in Patent Document 4, by the external operation, it can be moved in the organs, however, it is difficult that the image pick-up direction is easily changed.  
         [0028]     In view of such a problem, the present invention is attained, and the third object of the present invention is to propose the capsule type medical device by which the optical axis of the image pick-up lens can be easily tilted, and a part positioned in the slant direction can also be image picked-up.  
         [0029]     Further, the capsule type medical device written in Patent Document 5 can move, because is moved by rotating, along the inner wall surface in the it inside of small bowel whose inner diameter is small, however, in the stomach whose inner diameter is large, when it is rotated along the inner wall surface, because there is a possibility that it is rotated in unexpected direction, it is difficult to introduce the objective position.  
         [0030]     In view of such a problem, the present invention is attained, and the fourth object of the present invention is to propose the capsule type medical device in which, when it is structured so that it can move straightly, even when in the organ whose inner diameter is large, it can surely self-run to the objective position.  
         [0031]     Other than that, the fifth object of the present invention is to propose the capsule type medical device by which can inject the medicine accommodated inside for cure in the body, or sample the body fluid for inspection.  
         [0032]     Item 1. In the capsule type medical device having the image pick-up optical system for image picking-up in the organ in the body, the capsule type medical device characterized in that the bellow part stretching and contracting in the length direction is formed on the outer peripheral surface.  
         [0000]     Item 2. The capsule type medical device written in Item 1, wherein the bellow part is formed in the stretched condition, and it is sheathed by a member soluble in the organs in the contracted condition.  
         [0033]     Item 3. The capsule type medical device written in Item 1 or 2, wherein it has the bellow part which stretches and contracts in the length direction on the outer peripheral surface, and the first bellow member which at least sheathes the image pick-up lens, and the second bellow member which has the bellow part stretching and contracting in the length direction on the outer peripheral surface, and at least sheathes the image processing section for image processing the image picked-up by the image pick-up lens.  
         [0000]     Item 4. The capsule type medical device written in Item 3, wherein, the member at least holding the image pick-up lens, and the member at least holding the image processing section, are connected by the universal joint.  
         [0034]     Item 5. In the capsule type medical device having the image pick-up optical system for image picking-up in the body, the capsule type medical device which characterized in that it has the image pick-up optical system structured by the first lens and the second lens, and the sheath member at whose leading edge part, the first lens is formed, and which sheathes the second lens, and on whose outer peripheral surface, the bellow part stretching and contacting in the length direction is formed, and a drive member for stretching and contacting the bellow part, and when the drive member is driven and the bellow part is stretched and contacted, and the first lens is moved in the optical axis direction, the distance between lenses of the first lens and the second lens is changed.  
         [0000]     Item 6. The capsule type medical device written in Item 5, wherein, when the distance between lenses of the first lens and the second lens is changed, the subject distance to be focused is changed.  
         [0000]     Item 7. The capsule type medical device written in Item 5, wherein, when the distance between lenses of the first lens and the second lens is changed, the focal distance of the image pick-up optical system is changed.  
         [0035]     Item 8. In the capsule type medical device having the image pick-up optical system for image picking-up in the body, the capsule type medical device which is characterized in that: it has a front part housing the image pick-up optical system and image pick-up element, the rear part housing the image processing section for processing the picked-up image, and the joint rotatably connecting the front part and the rear part, and the bellow part which at least sheathes the joint, connected to the front part and rear part and stretches and contracts in the length direction, the drive part is driven, and when a predetermined part in the peripheral direction of the bellow part is contracted and the other part to the predetermined part is stretched, the axis center of the front part to the axis center in the length direction of the rear part is tilted in the predetermined direction.  
         [0036]     Item 9. The capsule type medical device written in Item 8, wherein the joint is a universal joint.  
         [0000]     Item 10. The capsule type medical device written in any one Item of Items 5-9, wherein the micro-mini motor for driving the drive member is provided.  
         [0037]     Item 11. The capsule type medical device characterized in that: it has the bellow part stretching and contracting in the length direction on the outer peripheral surface, the bellow part is composed of a plurality of bellow groups, and when a predetermined bellow group is individually stretches and contracts, it self-run.  
         [0038]     Item 12. The capsule type medical device written in Item 11, wherein the movement in which only the first bellow group positioned at the leading edge of the advancing direction stretches from the contract condition of all bellow groups and the leading edge part is moved forward, next, the first bellow group is contracted, and the second bellow group positioned at back of the first bellow group is stretched, in succession, when the second bellow group is contracted, the third bellow group positioned at back of the second bellow group is stretched, is successively repeated, and after the n-bellow positioned at the trailing edge of the advancing direction is stretched, when it is contracted, the trailing edge part advances forward.  
         [0000]     Item 13. The capsule type medical device written in Item 11 or 12, wherein the total length of the bellow groups in the stretched condition is shorter than the total length of the bellow groups in the contracted condition at the time of standstill.  
         [0039]     Item 14. The capsule type medical device written in any one Item of Items 11-14, wherein the member included by the bellow part is divided into at least two units, and each of units is connected by the universal joint, and bends around the universal joint.  
         [0040]     Item 15. The capsule type medical device written in Item 14, wherein it has the drive member for stretching and contracting the bellow part, and when drives the drive member, contracts a predetermined part in the peripheral direction of the bellow part, and stretches the other part to the predetermined part, the axis center of the other unit to the axis center in the length direction of one unit is bent around the universal joint.  
         [0041]     Item 16. The capsule type medical device written in any one Item of Items 11-15, wherein it is provided with at least the image pick-up lens, illumination part for illuminating the subject, image pick-up element for photo-electrically converting the picked-up image, image processing section for image processing the photo-electrically converted image, and transmission and reception section for transmitting the image processed image to the external devices.  
         [0000]     Item 17. The capsule type medical device written in any one Item of Items 11-16, wherein it is provided with the conductive high polymer actuator for driving the bellow group.  
         [0000]     Item 18. The capsule type medical device written in any one Item of Items 11-16, wherein it is provided with the shape memory alloy for driving the bellow group.  
         [0042]     Item 19. The capsule type medical device which is characterized in that: it is provided with the bellow part which is provided on the outer peripheral surface and stretches and contracts in the length direction, drive part for driving the bellow part, accommodation part connected to the bellow part, accommodates inside the medicine, and having the communicating hole communicating to the outside, and when the drive part is driven in the body, and the bellow part in the stretched condition is contracted, the medicine accommodated in the accommodation part is injected from the communicating hole.  
         [0043]     Item 20. The capsule type medical device which is characterized in that: it is provided with the bellow part which is provided on the outer peripheral surface and stretches and contracts in the length direction, drive part for driving the bellow part, accommodation part connected to the bellow part, accommodates inside the sampled body fluid, and having the communicating hole communicating to the outside, and when the drive part is driven in the body, and the bellow part in the contracted condition is stretched, the body fluid is sampled into the accommodation part from the communicating hole.  
         [0044]     Item 21. The capsule type medical device written in Item 19 or 20, wherein it is provided with at least the image pick-up lens, illumination part for illuminating the subject, image pick-up element for photo-electrically converting the picked-up image, image processing section for image processing the photo-electrically converted image, and transmission section for transmitting the image processed image to the external devices.  
         [0000]     Item 22. The capsule type medical device written in any one Item of Items 19-21, wherein the drive part has the micro-mini motor.  
         [0045]     According to the capsule type medical device written in Item 1, because the bellow part stretching and contracting in the length direction is formed on the outer peripheral surface, it is bendable in the length direction, even when the capsule type medical device is moved in the body by the fibrillation, and passes the place which is narrow like as the small bowel and bent many times, different from the conventional capsule type medical device, the risk to be caught is small.  
         [0046]     According to the capsule type medical device written in Item 5, because the distance between lenses of the first lens and the second lens can be changed by the operation from the outside the body, the subject distance to be focused can be changed to near distance or far distance, or composed focal distance of the first lens and the second lens can be changed to the short focal distance or long focal distance.  
         [0047]     According to the capsule type medical device written in Item 8, by the operation from the outside the body, while the capsule type medical device is fixed, the optical axis of the image pick-up optical system can be tilted in the desired direction.  
         [0048]     According to the capsule type medical device written in Item 11, it can self-run by a simple structure, and as the conventional technology, because the movement is not rotation movement, but the straight movement, even when the capacity is large place, it can surely self-run and approach to the objective position.  
         [0049]     According to the capsule type medical device written in Item 19, the medicine accommodated inside can be directly injected to the disease for cure.  
         [0050]     According to the capsule type medical device written in Item 20, the body fluid in a predetermined organ can be sampled for inspection. 
     
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       [0051]      FIG. 1  is a view in the organs of the human body.  
         [0052]      FIG. 2  is an enlarged view in which the capsule type medical device is caught at A part of  FIG. 1 .  
         [0053]      FIG. 3  is a sectional view of the capsule type medical device before use.  
         [0054]      FIG. 4  is a sectional view of the capsule type medical device after it is taken down.  
         [0055]      FIG. 5  is a sectional view of the bent capsule type medical device.  
         [0056]      FIG. 6  is an enlarged view in which the capsule type medical device passes A part of  FIG. 1 .  
         [0057]      FIG. 7  is a sectional view of the capsule type medical device when the subject of the near distance is image picked-up from the front.  
         [0058]      FIG. 8  is a sectional view of the capsule type medical device when the subject of the far distance is image picked-up from the front.  
         [0059]      FIG. 9  is a sectional view of the capsule type medical device when the image pick-up optical system is tilted for image picking-up.  
         [0060]      FIG. 10  is a sectional view of the capsule type medical device in the stationary condition.  
         [0061]      FIG. 11  is a view showing the sequence in which the capsule type medical device self-runs.  
         [0062]      FIG. 12  is an enlarged view when as the actuator, the conductive high polymer actuator is used.  
         [0063]      FIG. 13  is an operation principle view of the conductive high polymer actuator.  
         [0064]      FIG. 14  is an enlarged view when as the actuator, the shape memory alloy is used.  
         [0065]      FIG. 15  is a side view and an upper surface view of the capsule type medical device which houses one universal joint and self-runs.  
         [0066]      FIG. 16  is an upper surface view of the capsule type medical device which houses two universal joints and self-runs.  
         [0067]      FIG. 17  is a sectional view of the capsule type medical device for injecting the medicine.  
         [0068]      FIG. 18  is a sectional view of the capsule type medical device for sampling the body fluid. 
     
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT  
     The First Embodiment  
       [0069]     Referring to the drawing, the first embodiment according to the capsule type medical device of the present invention will be described.  
         [0070]     Initially, based on  FIG. 3 , the structure of the capsule type medical device will be described, however,  FIG. 3  is a sectional view of the capsule type medical device before use.  
         [0071]     The present capsule type medical device  101  is structured by the front part  102 , rear part  103 , and the connection part  104  connecting the front part  102  and the rear part  103 .  
         [0072]     In the front part  102 , the image pick-up lens  121  structured in the wide angle, and for image picking-up in the organs of the person, image pick-up element  122  composed of CCD or CMOS, and for image-forming the image, picked-up by the image pick-up lens  121  and for photoelectric converting, and a plurality of illumination members  123  composed of LED, and for illuminating the organ to be image picked-up at the time of image picking-up, are housed, and they are held by the connection member  141 .  
         [0073]     Then, the trailing edge part  125   c  of the front body  125  (the first bellow member) having the flexible bellow part  125   a  on the outer peripheral surface is fixed to the connection member  141  of the connection part  104 , and the front body  125  sheathes the inside image pick-up element  122  in the water-tight condition. Hereupon, the leading edge part  125   b  of the front body  125  is formed into sphere-like so that it easily passes in the organ, and at least the leading edge part  125   b  is formed into transparent and equal thickness, and structured so that it does not hinder the image picking-up.  
         [0074]     Hereupon, the leading edge part  125   b  is formed so that the wall thickness is changed from the central part to the peripheral part, and is made a convex lens or concave lens, and may also structure the image pick-up optical system together with the image pick-up lens  121 .  
         [0075]     In the rear part  103 , the image processing section  131  for processing the image photoelectric converted by the image pick-up element  122 , transmission and reception section  132  for transmitting the image processed in the image processing section  131  to outside the body by the wireless, and for receiving the wireless signal from outside the body, and the battery  133  for supplying the electric source to each circuit part are housed, and they are held by the rear part holding member  142 .  
         [0076]     Then, the leading edge part  135   c  of the rear body  135  (the second bellow member) having the flexible bellow part  135   a  on the outer peripheral surface is fixed to the connection member  141  of the connection part  104 , and the rear body  135  sheathes the inside image processing section  131  in the water-tight condition. Hereupon, the trailing edge part  135   b  of the rear body  135  is also formed into sphere-like so that it easily passes in the organ.  
         [0077]     In the connection part  104 , the spherical member  143  having the spherical part  143   a  formed into spherical, is integrally connected to the connection member  141 , spherical part  143   a  is inserted into spherical hole  142   a  provided in the rear part holding member  142 , and the top part of the spherical part  143   a  is held by the holding plate  144  fixed to the rear part holding member  142 .  
         [0078]     By the above description, because the spherical part  143   a  is rotatable to the spherical hole  142   a , the universal joint is structured, and the connection member  141  is freely rotated in all directions to the rear part holding member  142 .  
         [0079]     Hereupon, as the universal joint, it is not limited to such a structure, but, for example, the first axis is rotatably passed into the C-shaped first member, the second axis is rotatably passed into the other C-shaped second member, and the second axis is rotatably passed into the hole provided in the peripheral wall center of the first axis, and the first axis and the second axis are crossed at right angle, and it may also be the universal joint in which the second member is 3-dimensionally rotated to the first member.  
         [0080]     The capsule type medical device  101  is structured as described above, further, before use, in the condition that the bellow part  125   a  of the front body  125  and the bellow part  135   a  of the rear body  135  are contracted, they are sheathed by the sheath member  151 , so that the capsule type medical device  101  is easily taken down. Hereupon, the sheath member  151  is formed of the material which is dissolved by the body fluid in the organ, for example, the gelatin formed of the bone of caw and the skin of pig, or the oblate formed of the agar and starch. Further, because the front body  125 , rear body  135  are molded in the condition that the bellow parts  125   a ,  135   a  are stretched, when the sheath member  151  which sheathes is dissolved, the bellow parts  125   a ,  135   a  are released from the contracted condition, and automatically stretched.  
         [0081]     Next, the mode of operation of the capsule type medical device  101  will be described.  
         [0082]     Initially, the tested subject takes down the capsule type medical device  101  from the direction of the front part  102 . In this time, because, in the capsule type medical device  101 , the bellow parts  125   a ,  135   a  of the front body  125 , rear body  135  are in the contracted condition, and the total length is short, and the bellow parts  125   a ,  135   a  having the concave and convex are sheathed, the resistance for taking down is small.  
         [0083]     The taken down capsule type medical device  101  passes the oesophagus, when it arrives at the stomach, the sheath member  151  is dissolved by the gastric juice. Hereby, the contracted bellow parts  125   a ,  135   a  of the front body  125 , rear body  135  are as shown in  FIG. 4 , released from the contracted condition, automatically stretched, and becomes the condition at the time of molding. Accordingly, the capsule type medical device  101  becomes narrow and long, and easily directed in the advancing direction in the organ, and is easily moved by the fibrillation. The capsule type medical device  101  is moved to the stomach, small bowel, and large bowel by the fibrillation. Then, from the transmission and reception section  132  of the capsule type medical device  101 , the signal except the image signal is continuously transmitted to outside the body. Accordingly, by the external devices, not shown, composed of the receiving part, data processing part, display part and input part, the inspection doctor can grasp the position in the body of the capsule type medical device  101 .  
         [0084]     In the case where the capsule type medical device  101  arrives at a predetermined organ, when the inspection doctor operates the external device for image picking-up this organ and transmits the image pick-up signal, the transmission and reception section  132  of the capsule type medical device  101  receives the signal. Then, the signal received by the transmission and reception section  132  is transmitted to the image processing section  131 , and by the control of the control section provided in the image processing section  131 , the image pick-up of the organ is conducted. Hereupon, when image pick-up, the illumination member  123  is turned on, and illuminates the organ.  
         [0085]     The image of the organ which is the subject, is image formed on the image pick-up element  122  by the image pick-up lens  121 , and photoelectric converted. Then, the photoelectric converted signal is A/D conversion processed in the image processing section  131  and becomes the image signal, and compression processed and temporarily stored in the memory. The image signal in the memory is modulated in the transmission and reception section  132 , and transmitted to the external device outside the body in the electric wave through the antenna.  
         [0086]     Accordingly, the inspection doctor can observe the image of the organ of the tested subject by the external device or store in a predetermined memory mean.  
         [0087]     Hereupon, in the structure described above, when the capsule type medical device  101  is not operated, so that the battery  133  does not consume wastefully, the power source switch interlocking with the stretch and contraction of the bellow part  135   a  of the rear body  135 , is provided, only when the sheath member  151  is dissolved in the body and the bellow part  135   a  is stretched, the power source switch may also be turned on.  
         [0088]     Further, when from the coil arranged outside the body, the electric power is supplied to the power receiving coil provided in the capsule type medical device  101  by the electromagnetic induction, the battery  133  is not necessary.  
         [0089]     Further, the posture sensor is housed in the rear part  103 , and the posture of the capsule type medical device  101  may also be transmitted to the external device by the transmission and reception section  132 .  
         [0090]     In this manner, the capsule type medical device  101  is moved in the body by the fibrillation, however, when it passes a place which is narrow and bent many times like as the small bowel, there is a possibility that the conventional capsule type medical device is caught.  
         [0091]     However, in the present capsule type medical device  101 , a cover sheathing the inside member of the front part  102  and the rear part  103  is structured by the front body  125  having the bellow part  125   a  and the rear body  135  having the bellow part  135   a , and the inside member is accommodated by being divided into the front part  102  side and the rear part  103  side, and because they are connected by the universal joint of the connection part  104 , as shown in  FIG. 5 , the front part  102  can freely rotate in all directions to the rear part  103 . Accordingly, when it is conveyed to the bending part of the organ like A shown in  FIG. 1 , as shown in the enlarged view of  FIG. 6 , because the capsule type medical device  101  itself is bent corresponding to the curvature of the bending part, it can smoothly pass without being caught. Hereupon, for the bellow part of the capsule type medical device  101 , the condition shown in  FIG. 4  is the normal condition, however, when it passes the bending part, for example as shown in  FIGS. 5, 6 , because one hand bellow part is stretched, the other bellow part is compressed, when the capsule type medical device  101  passes the bending part and arrives at a straight line part, it naturally restores to a condition of  FIG. 4 .  
         [0092]     Further, although the below part  125   a  contributes to an action to prolong the total length in the organ, because it does not contribute to the passage of the bending part, it can also be neglected.  
         [0093]     Further, two or more universal joints may also be provided, and in this case, 3 sets or more bellow parts are provided.  
         [0094]     Further, when the gap between the front body  125 , rear body  135  for sheathing the inside member and the inside member, is enough, even when the connection section  104  does not necessarily have the universal joint, it bends in all directions by the bellow parts  125   a ,  135   a . Further, in this case, the bellow part may also be one set or 3 sets or more, further, the bellow parts may also be formed on all of the outer peripheral wall.  
       The Second Embodiment  
       [0095]     Referring to the drawings, the second embodiment according the capsule type medical device of the present invention will be described below.  
         [0096]     Initially, based on  FIG. 7 , the structure of the capsule type medical device will be described, and  FIG. 7  is a sectional view of the capsule type medical device when the subject of the near distance is image picked-up in the front.  
         [0097]     The present capsule type medical device  201  is structured by the front part  202 , rear part  203 , and the connection part  204  connecting the front part  202  and the rear part  203 .  
         [0098]     In the front part  202 , the second lens  221 , the image pick-up element  222  for image forming and photoelectric converting the picked-up image by the image pick-up optical system which will be described later, and a plurality of illumination members  223 , composed of LED, for illuminating the organ to be picked-up at the time of the image pick-up, are housed, and they are held by the connection member  241  of the connection part  204 .  
         [0099]     Then, the trailing edge part  225   c  of the front body  225  having the flexible bellow part  225   a  on the outer peripheral surface is fixed to the connection member  241 , and the sheath member  25  sheathes the housed second lens  221  in the water-tight condition. Further, on the leading edge part of the front body  225 , the first lens  225   b  integrally molded with the front body  225  is formed, and the image pick-up optical system is structured by the first lens  225   b  and the second lens  221 .  
         [0100]     Further, the leading edge part  225   d  of the front body  225  is formed into spherical, so that it can easily pass in the organ, and at least a part in which the first lens is formed, is formed into transparent.  
         [0101]     Hereupon, the first lens  225   b  may also not necessarily be integrally molded with the front body  225 , but, may also be independently formed and fixed to the front body  225 . In this case, it is more desirable that it is fixed to a position at which the relative interval to the second lens  221  can be changed.  
         [0102]     Further, in the front part  202 , a plurality of drive members  226  for stretching and contracting the bellow part  225   a  of the bellow member  225  from inside, are provided on the periphery, and when the drive member  226  goes forward and backward in the direction of optical axis O, the bellow part  225   a  is stretched and contracted in the direction of the optical axis O. In this case, a plurality of drive members  226  simultaneously integrally goes forward and backward. Further, as the actuator for moving the drive member  226 , it is desirable that the micro-mini motor is used.  
         [0103]     Then, when the drive member  226  is moved to the direction of the image pick-up element  222 , the bellow part  225   a  is compressed, and becomes the condition of  FIG. 8 . In this case, the bellow part  225   a  is molded in the condition that it is a little stretched condition from the condition of  FIG. 7 , and when the drive member  226  presses it, the bellow part  225   a  is shrunk.  
         [0104]     Hereupon, it may also be structured that the bellow part  225   a  is molded in the condition that it is shrunk, inverse to 2 in  FIG. 7 , the drive member  226  presses it from the side of the image pick-up element  222 , and the bellow part  225   a  is stretched.  
         [0105]     In the rear part  203 , the image processing section  231  for processing the image photoelectric converted by the image pick-up element  222 , the transmission and reception section  232  having the antenna, for transmitting the image processed in the image processing section  231  in the wireless to the outside of body, and for receiving the wireless signal from the outside of body, and the battery  232  for supplying the power source to each of circuit parts are housed, and they are held by the rear part holding member  242 .  
         [0106]     Then, the leading edge part  235   c  of the rear body  235  having the flexible bellow part  235   a  on the outer peripheral surface is fixed to the connection member  241  of the connection part  204 , and the intermediate part  235   d  of the rear body  235  is fixed to the trailing edge part  242   b  of the rear part holding member  242 , and the rear body  235  sheathes the inside image processing section  231  in the water-tight condition. Hereupon, the trailing edge part  235   b  of the rear body  235  is also formed into spherical so that it easily passes in the organ.  
         [0107]     Further, in the rear part  203 , the drive member  236  for moving the bellow part  235   a  of the rear body  235  from the inside, are provided on the periphery at the plural places, and by the control of the control section provided in the image processing section  231 , each of drive members  236  independently goes forward and backward. Hereby, desired drive member  236  is moved backward, presses the bellow part  235   a  and makes shrunk. On the one hand, the other drive member  236  is moved forward, because it retreats from the bellow part  235   a , the bellow part  235   a  is stretched. Hereupon, in the normal condition, each drive member  236  retreats forward from the bellow part  235   a , and the bellow part  235   a  is in the condition at the time of molding. Further, as the actuator for driving each of drive members  236 , it is desirable that the micro-mini motor is used.  
         [0108]     In the connection part  204 , the spherical member  243  having the spherically formed spherical part  243   a  is integrally connected to the connection member  241 , the spherical part  243   a  is inserted into a spherical hole  242   a  provided in the rear par t holding member  242 , and the top part of the spherical part  243   a  is held by the holding plate  244  fixed to the rear part holding member  242 .  
         [0109]     From the above description, because the spherical part  243   a  is rotatable to the spherical hole  242   a , the universal joint is structured, and the connection member  241  is freely rotated to the rear part holding member  242  in all directions.  
         [0110]     Hereupon, as the universal joint, it is not limited to such a structure, but the universal joint in which, for example, the first axis is rotatably inserted into C-shaped first member, and the second axis is rotatably inserted into other C-shaped second member, and the second axis is rotatably inserted into the hole provided in the peripheral wall center of the first axis, and crossed at right-angle, and the second member rotates 3-dimensionally to the first member, may also be allowable.  
         [0111]     Other than that, relating to the battery, when the electric power is supplied from the coil arranged outside the body to the power receiving coil provided in the capsule type medical device  201  by the electromagnetic induction, the battery is unnecessary.  
         [0112]     Further, the posture sensor is housed in the rear part  203 , and the posture of the capsule type medical device  201  may also be transmitted to the external device by the transmission and reception section  232 .  
         [0113]     Next, the mode of operation of the capsule type medical device  201  will be described.  
         [0114]     Initially, the tested subject takes down the capsule type medical device  201  from the direction of the front part  102 .  
         [0115]     Then, The capsule type medical device  201  is moved to the stomach, small bowel, and large bowel by the fibrillation. From the transmission and reception section  232  of the capsule type medical device  201 , the signal except the image signal is continuously transmitted to outside the body. Accordingly, by the external devices, not shown, composed of the receiving part, data processing part, display part and input part, the inspection doctor can grasp the position in the body of the capsule type medical device  201 .  
         [0116]     Hereupon, depending on the case, there is a case where the capsule type medical device  201  is inserted from the anus.  
         [0117]     In the case where the capsule type medical device  201  arrives at a predetermined organ, when the inspection doctor operates the external device for image picking-up this organ and transmits the image pick-up signal, the transmission and reception section  232  of the capsule type medical device  201  receives the signal. Then, the signal received by the transmission and reception section  232  is transmitted to the image processing section  231 , and by the control of the control section provided in the image processing section  231 , the image pick-up of the organ is conducted. Hereupon, when image pick-up, the illumination member  223  is turned on, and illuminates the organ.  
         [0118]     The image of the organ which is image picked-up, is image formed on the image pick-up element  222  by the image pick-up lens  221 , and photoelectric converted. Then, the photoelectric converted signal is A/D conversion processed in the image processing section  231  and becomes the image signal, and compression processed and temporarily stored in the memory. The image signal in the memory is modulated in the transmission and reception section  232 , and transmitted to the external device outside the body in the electric wave through the antenna.  
         [0119]     Accordingly, the inspection doctor can observe the image of the organ of the tested subject by the external device or store in a predetermined memory mean.  
         [0120]     Further, in the case where the organ is image picked-up, in the capsule type medical device  201  in the condition of  FIG. 7 , when the focus of the image is adjusted on the part of the near direction and the part of the far distance is not sharp, when the inspection doctor operates the external device and transmits the distance signal to the capsule type medical device  201 , through the transmission and reception section  232 , the control section in the image processing section  231  controls the micro-mini motor and moves the drive member  226 . Then, a plurality of drive members  226  simultaneously press the bellow part  225   a  of the front body  225  and contract it, and changes from the condition of  FIG. 7  to the condition of  FIG. 8 , and the first lens  225   b  is gone back on the side of the image pick-up element  222 . Hereby, the distance between lenses of the first lens  225   b  and the second lens  221  is reduced, the far distance part of the image pick-up element  222  is focused, and the focus of the image becomes sharp.  
         [0121]     In this manner, by the operation from the outside the body, the subject distance to be focused, can be changed.  
         [0122]     Further, by the lens composition of the first lens  225   b  and the second lens  221 , when the distance between lenses is changed, the focal distance can also be changed. Accordingly, for example, the condition of  FIG. 7  is long focal distance, and the condition of  FIG. 8  is short focal distance, and from the same position, it can be image picked-up at different angle of view.  
         [0123]     Hereupon, when the drive member  226  is moved by the micro-mini motor, even when the photographing distance is changed, or the focal distance is changed, it can be changed in step-less or set predetermined step number.  
       The Third Embodiment  
       [0124]     Referring to the drawings, the third embodiment according the capsule type medical device of the present invention will be described below.  
         [0125]     When the image of the organs of the tested subject is observed by the inspection doctor by an external device, there is a case where an anxious disease is discovered at the periphery of the picked-up image. In this case, as described above, the lens may be changed to the wide lens and image picked-up so that the wide range is picked-up, however, there is a problem that the image becomes small and it becomes difficult to be observed.  
         [0126]     In this case, when the inspection doctor operates the external device and the tilt signal is transmitted to the capsule type medical device  201 , the control section in the image processing section  231  controls the micro-mini motor by the transmission and reception section  232 , and each drive member  236  is moved. Then, the drive member  236  positioned in the direction in which the image pick-up optical system is wanted to tilt is moved backward, and the bellow part  235   a  is pressed and contracted. Hereby, as shown in  FIG. 9 , the front part  202  rotates in the direction of the drive member  236  moved backward, around the spherical apart  243   a . In this case, because to the contracted bellow part  235   a , the other bellow part  235   a  placed at least 180° position is stretched, the drive member  236  in the vicinity of the stretched bellow part  235   a  is moved forward, and retreated from the bellow part  235   a . Accordingly, while the capsule type medical device  201  is fixed, the axis center of the front part  202 , that is, the optical axis O of the image pick-up optical system is tilted to the axis center C of the rear part  203 , and the organ in the desired direction can be image picked-up.  
         [0127]     Hereupon, the above structure is reversed, and the drive member  236  placed in the reversal position to the direction wanted to tilt the image pick-up optical system is moved forward, and the bellow part  235   a  may also be pressed and stretched. Hereby, the bellow part  235   a  positioned in the direction wanted to tilt the image pick-up optical system is contracted, and it is in the condition same as described above.  
         [0128]     Further, when the drive member  236  is moved by the micro-mini motor, the image pick-up optical system can be tilted in the arbitrary direction at the arbitrary angle.  
         [0129]     In this manner, only the image pick-up optical system is tilted in the desired direction without moving the capsule type medical device, and in that condition, further focused subject distance or focal distance can be changed.  
         [0130]     Further, as described above, a fact that the front part  202  of the capsule type medical device  201  is tilted to the rear part  203 , is not only effective for changing the photographing direction, but also effective when the capsule type medical device  201  passes the organ which is narrow and has many bending part.  
         [0131]     Hereupon, in the above description, the bellow part  235   a  is formed in the rear body  235 , however, the bellow part  235   a  is made the separated member from the rear body  235 , and may also connect to the front part  202  and rear part  203 .  
         [0132]     Further, the capsule type medical device  201  described as above, has the bellow part  225   a  and the bellow part  235   a , after the photographing direction is changed, the subject distance to be focused, or focal distance can be changed, however, only the bellow part  225   a  is provided, and it may also be allowable that the subject distance to be focused, or focal distance is only changed, or only the bellow part  235   a  is provided, and the photographing direction is only changed.  
         [0133]     Further, as the actuator for driving the drive members  226 ,  236 , it is not necessarily limited to the micro-mini motor, but the conductive high polymer actuator, shape memory ally, piezo-electric element may also be used.  
         [0134]     Other than that, in the above description, the drive members  226 ,  236  of the capsule type medical device  201  positioned in the body of the tested subject, are operated by the communication from outside the body, however, the drive members  226 ,  236  may also be automatically driven. That is, CPU having the program for driving the drive members  226 ,  236  is housed in the capsule type medical device  201 , and when a predetermined condition is satisfied, the drive members  226 ,  236  are automatically driven, and the subject distance or focal distance may also be changed.  
       The Fourth Embodiment  
       [0135]     Referring to the drawing, the fourth embodiment according to the capsule type medical device of the present invention will be described.  
         [0136]     Initially, based on  FIG. 10 , the structure of the capsule type medical device will be described, however,  FIG. 10  is a sectional view of the capsule type medical device in the stationary condition.  
         [0137]     The present capsule type medical device  301  is structured by the front part  302 , rear part  303 , and the bellow part  304  connecting the front part  302  and the rear part  303 .  
         [0138]     In the front part  302 , the image pick-up lens  311  for image picking-up in the organ of the person, image pick-up element  312  composed of CCD or CMOS, and for image-forming the image, picked-up by the image pick-up lens  311  and for photoelectric converting, and a plurality of illumination parts  313  composed of LED, and for illuminating the organ to be image picked-up at the time of image picking-up, are housed, and they are held in the font of the front part substrate  315 . Further, in the rear of the front part substrate  315 , the image processing section  316  for processing the image photoelectric converted by the image pick-up element  312  is arranged, and held by the front part substrate  315 .  
         [0139]     Then, the image pick-up lens  311  held by the front part substrate  315  is sheathed by the front body  318  in the water-tight condition. Hereupon, at least leading edge part  318   a  of the front body  318  is formed into transparent and equal in thickness, and structured so that it does not hinder the image pick-up.  
         [0140]     In the rear part  303 , the transmission and reception section  321  having the antenna, for transmitting the image processed in the image processing section  316  in the wireless to the outside of body, and for receiving the wireless signal from the outside of body, and the battery  322  for supplying the power source to each of circuit parts are housed, and they are held by the rear part substrate  325 . Further, in the front part side, which is the reversal side of the rear part substrate  325 , the control section  326  for controlling the timing of the image pick-up, or for controlling for self-running the capsule type medical device which will be described later, is arranged, and held by the rear part substrate  325 .  
         [0141]     Then, the transmission and reception section  321  held by the rear part substrate  325  is sheathed by the rear body  328  in the water-tight condition.  
         [0142]     Further, the image processing section  316  of the front part, the control section  326  of the rear part  303 , the battery  322  and the transmission and reception section  321  are flexibly and electrically connected by the connection member  341  composed of a flexible print substrate or a plurality of lead wires.  
         [0143]     Herein, when the bellow part  304  is compressed as in  FIG. 10 , the maximum outer diameter of the bellow part  304  is formed larger than the outer diameter of the front body  318  and the rear body  328 .  
         [0144]     Further, although it is not shown in  FIG. 10 , the bellow part  304  is composed of a plurality of bellow groups as will be described later, and the actuator for respectively stretching and contracting a predetermined bellow group is provided in the inside of the bellow part  304 .  
         [0145]     Next, the self-running action of the capsule type medical device will be described.  
         [0146]     Initially, when the tested subject takes down the capsule type medical device from the direction of the front part  302 , the capsule type medical device passes the oesophagus, and arrives at the stomach, and is moved to the small bowel, and large bowel by the fibrillation. Then, from the transmission and reception section  321  of the capsule type medical device, the signal except the image signal is continuously transmitted to outside the body. Accordingly, by the external devices, not shown, composed of the receiving part, data processing part, display part and input part, the inspection doctor can grasp the position in the body of the capsule type medical device.  
         [0147]     In the case where the capsule type medical device arrives at a predetermined organ, when the inspection doctor operates the external device for image picking-up this organ and transmits the image pick-up signal, the transmission and reception section  321  of the capsule type medical device receives this signal. Then, by the signal received by the transmission and reception section  321 , the control section  326  controls and the image pick-up of the organ is conducted. Hereupon, when image pick-up, the illumination part  323  is turned on, and illuminates the organ.  
         [0148]     The image of the organ which is the subject, is image formed on the image pick-up element  312  by the image pick-up lens  311 , and photoelectric converted. Then, the photoelectric converted signal is A/D conversion processed in the image processing section  316  and becomes the image signal, and compression processed and temporarily stored in the memory. The image signal in the memory is modulated in the transmission and reception section  321 , and transmitted to the external device outside the body in the electric wave through the antenna.  
         [0149]     Accordingly, the inspection doctor can observe the image of the organ of the tested subject by the external device or store in a memory mean such as the hard disk or CD.  
         [0150]     Herein, in the case where it is wanted that the capsule type medical device in the organ is self-run to the arbitrary position, and image pick-up is conducted, when the inspection doctor transmits the movement signal by the external device, the transmission and reception section  321  of the capsule type medical device receives this signal, and based on the signal, the control section  326  controls the actuator, not shown, and stretches and contracts the bellow group of the bellow part  304 , and the capsule type medical device is self-run.  
         [0151]     Based on  FIG. 11 , the sequence for self-running the capsule type medical device by this stretching and contracting of the bellow group, will be described.  
         [0152]      FIG. 11  shows the condition that the capsule type medical device self-runs in the sequence of (A)-(F) to the right direction in the drawing.  
         [0153]     The bellow part  304  of the capsule type medical device  301  shown in  FIG. 11  is formed of 4 bellow groups J 1 -J 4  each of which has 3 protrusions, and each of bellow groups independently stretches and contracts.  
         [0154]     Initially, in  FIG. 11 (A), the capsule type medical device  301  is in the condition before self-running, and the bellow groups J 1 -J 4  are all contracted and grounded.  
         [0155]     Next, in  FIG. 11 (B), when only the leading edge bellow group J 1  (the first bellow group) is stretched, the front part  302  (leading edge part) is moved forward. In this case, because the bellow groups J 1 -J 4  are grounded, even when the bellow group J 1  and the front part  302  are floated, they are held, and the capsule type medical device  301  does not fall forward.  
         [0156]     In succession, in  FIG. 11 ©, the stretched bellow group J 1  is contracted, and the second bellow group J 2  (the second bellow group) is stretched. In this case, even when the bellow group J 2  is floated, because the bellow group J 1  and bellow groups J 3 , J 4  are grounded, the capsule type medical device  301  does not fall forward and backward.  
         [0157]     In succession, in  FIG. 11 (D), the stretched bellow group J 2  is contracted, and the third bellow group J 3  (the third bellow group) is stretched. In this case, even when the bellow group J 3  is floated, because the bellow groups J 1 , J 2  and bellow group J 4  are grounded, the capsule type medical device  301  does not fall forward and backward.  
         [0158]     In succession, in  FIG. 11 (E), the stretched bellow group J 3  is contracted, and the trailing edge bellow group J 4  is stretched. In this case, even when the bellow group J 4  is floated, because the bellow groups J 1 -J 3  are grounded, the capsule type medical device  301  does not fall backward.  
         [0159]     Finally, in  FIG. 11 (F), the stretched bellow group J 4  is contracted, Hereby, the rear part  303  (trailing edge part) is moved forward, and the whole of the capsule type medical device  301  is moved forward from the condition of  FIG. 11 (A).  
         [0160]     When such a moving motion is repeated, the capsule type medical device  301  surely advances by little and little.  
         [0161]     Further, when the operation reversal to the above description is conducted, the capsule type medical device  301  is moved backward.  
         [0162]     In this manner, by the external operation, the capsule type medical device  301  can be self-run to a predetermined position in the organ, and the image pick-up can be done at an adequate position.  
         [0163]     Hereupon, the number of the bellow groups is not limited, and when the bellow group positioned at the most leading edge is the first bellow group, the n-th bellow group positioned at the most trailing edge is the n-th bellow group.  
         [0164]     Further, the number of protrusions of the bellow group is not also limited.  
         [0165]     Further, when the total length of the bellow group of stretched condition is shorter than the total length of the bellow group of the contracted condition at the time of stasis, it can stably and surely self-run.  
         [0166]     Next, the actuator for moving the bellow group will be described.  
         [0167]      FIG. 12  is an enlarged view when the conductive high polymer actuator is used as the actuator, and  FIG. 12 (A) is a view of the condition that the bellow part is contracted, and  FIG. 12 (B) is a view of the condition that the bellow part is stretched.  
         [0168]     In  FIG. 12 , the conductive high polymer actuator  351  is adhered to the bending each inside of the bellow part  304 . When the voltage is not applied on this conductive high polymer actuator  351 , the bellow part  304  is contracted as shown in  FIG. 12 (A), however, when the voltage is applied on the conductive high polymer actuator  351 , because the conductive high polymer actuator  351  is bent, the bellow part  304  is stretched as shown in  FIG. 12 (B).  
         [0169]     Herein, an example of the principle of operation of the conductive high polymer actuator  351  is shown in  FIG. 13 .  
         [0170]     In the conductive high polymer actuator  351 , gold is plated on both surfaces of the ion conductive high polymer gel  351   a  formed of positive ion or water molecule, and metal films  351   b ,  351   c  are formed, and the voltage of, for example, about 2V is applied on metal films  351   b ,  351   c  through the switch, not shown. Then, the conductive high polymer actuator  351  is bent on the side of the metal film  351   b  connected to the positive electrode side from the condition of  FIG. 13 (A) to the condition of  FIG. 13 (B).  
         [0171]     Further, as the actuator for moving the bellow group, the shape memory alloy may also be used, and this one example is shown in the enlarged view of  FIG. 14 .  
         [0172]      FIG. 14 (A) is a view of the condition that the bellow part is contracted,  FIG. 14 (B) is a view of the condition that the bellow part is stretched, and numeral  361  is the shape memory alloy. When the voltage is not applied on the shape memory alloy  361 , it is contracted as shown in  FIG. 14 (A), and the bellow part  304  is also contracted. However, when the voltage is applied on the shape memory alloy  361 , it Is heated, it is stretched as shown in  FIG. 14 (B), and the bellow part  304  is also stretched.  
         [0173]     Other than that, as the actuator for moving the bellow group, the piezo-electric element, or micro-mini motor may also be used.  
         [0174]     Further, the capsule type medical device  301  shown in  FIG. 11  is an embodiment which linearly self-runs, however, the universal joints shown in  FIGS. 3-5  are housed in the capsule type medical device  301 , and the capsule type medical device  301  may also be structured so that it is flexible in the length direction, and is moved in the body by the fibrillation, and can pass a position which is narrow and bending at many times like as the small bowel. Further, the drive member shown in  FIG. 9  is housed in the capsule type medical device and by the transmission from the outside, the capsule type medical device may also be bent in a predetermined direction and self-run.  
         [0175]      FIG. 15  is a view of the capsule type medical device  301  in which one universal joint is housed,  FIG. 15 (A) is its side view, and  FIG. 15 (B) is its upper surface view. In addition that the guide part  302   a  is provided on the bottom part of the front part  302 , the guide part  303   a  is provided on the bottom part of the rear part  303 , and it may also be bent as in  FIG. 15 (B) and self-run.  
         [0176]     Hereupon, the guide parts  302   a ,  303   a  may also be formed like as the rotating wheel.  
         [0177]      FIG. 16  is an upper surface view of the capsule type medical device  301  in which 2 universal joints are housed. As same as in  FIG. 15 (A), it has the guide parts  302   a ,  303   a . When the capsule type medical device  301  advances, the universal joint positioned forward as shown in  FIG. 16 (A) is bent, and when it goes backward, the universal joint positioned backward as shown in  FIG. 16 (B) may be bent. Further, as shown in  FIG. 16 (C), both of the universal joint positioned forward and the universal joint positioned backward are bent, and may also be gone forward, and backward.  
         [0178]     Of course, the number of the universal joint is not limited to one or two, but, 3 or more joints may also be provided.  
       The Fifth Embodiment  
       [0179]     Referring to the drawing, the fifth embodiment according to the capsule type medical device of the present invention will be described.  
         [0180]     Initially, referring to  FIG. 17 , the capsule type medical device for injecting the medicine in the organ for cure will be described.  
         [0181]      FIG. 17 (A) is a sectional view of the capsule type medical device when it is not operated, and initially, based on this view, description will be made.  
         [0182]     The present capsule type medical device  401  is structured by the front part  402 , rear part  403 , and the bellow part  404  connecting the front part  402  and the rear part  403 .  
         [0183]     In the front part  402 , the front part sheath member  411 , and the front part substrate  412  for holding the front part sheath member  411  are provided, and the medicine is accommodated in the about semi-spherical accommodation part  413  formed in the water-tight condition by the front part sheath member  411 , and the front part substrate  412 .  
         [0184]     In the rear part  403 , the rear part sheath member  421 , and the rear part substrate  422  for holding the rear part sheath member  421  are provided, and the micro-mini motor  424  (drive part), transmission and reception section  425 , control section  426  and battery  427  are housed in the about semi-spherical accommodation part  423  formed in the water-tight condition by the rear part sheath member  421 , and the rear part substrate  422 .  
         [0185]     Hereupon, the screw shaft  424   a  having the male screw is protruded to the front part side from the micro-mini motor  424 , and the male screw of the screw shaft  424   a  is engaged with the female screw of the female screw part  412   a  provided on the rear part side of the front part substrate  412 .  
         [0186]     The transmission and reception section  425  has the antenna and transmits the wireless signal, and makes find the position of the capsule type medical device at the outside the body, or receives the wireless signal from the outside of body so that the medicine is injected as will be described later.  
         [0187]     The control section  426  is CPU for controlling the micro-mini motor  424  or the transmission and reception section  425 .  
         [0188]     The battery  427  is the power source of the micro-mini motor  424 , the transmission and reception section  425 , and the control section  426 .  
         [0189]     Further, the guide shaft  422   a  is protruded from the rear part substrate  422  to the front part side, and the deep hole of the deep hole part  412   b  protruded to the rear part side from the front part substrate  412  and the guide shaft  422   a  are engaged. Then, two sets of such a guide shaft  422   a  and deep hole part  412   b  are provided, both of which have the phase of about 180° in the peripheral direction of the capsule type medical device.  
         [0190]     Further, a plurality of small holes  412   c  are provided in the front part substrate  412 , and the small hole  412   c  is covered by the filter  414  having the mesh by which the powder is not passed but the air can be passed.  
         [0191]     Next, the injection action of the medicine by the capsule type medical device  401  will be described.  
         [0192]     Initially, when the tested subject takes down the capsule type medical device in the condition of  FIG. 17 (A) from the direction of the front part  402 , the capsule type medical device passes the oesophagus, and arrives at the stomach, and is moved to the small bowel, and large bowel by the fibrillation. Then, from the transmission and reception section  425  of the capsule type medical device, the wireless signal is continuously transmitted to outside the body. Accordingly, by the external devices, not shown, composed of the receiving part, data processing part, display part and input part, the inspection doctor can grasp the position in the body of the capsule type medical device.  
         [0193]     In the case where the capsule type medical device arrives at a predetermined organ, when the doctor operates the external device for injecting the medicine in this organ for cure and transmits the injection signal, the transmission and reception section  425  of the capsule type medical device receives this signal. Then, by the signal received by the transmission and reception section  425 , the control section  426  controls and rotates the micro-mini motor  424 .  
         [0194]     When the micro-mini motor  424  is rotated, because the male screw of the screw shaft  424   a  is rotated to the female screw of the female screw part  412   a , the distance of the front part substrate  412  and the rear part substrate  422  comes close. Hereupon, in this case, because the guide shaft  122   a  of the rear part substrate  422  is engaged with the deep hole part  412   b  of the front part substrate  412 , there is no case where the rear part substrate  422  is rotated to the front part substrate  412  and twisted.  
         [0195]     Hereby, as shown in  FIG. 17 (B), the bellow part  404  is contracted and the inside space  431  surrounded by the front part substrate  412 , rear part substrate  422 , and bellow part  404  is reduced, and the air in the inside space  431  is compressed. Accordingly, the inside force of the inside space  431  is increased, and the inside pressure of the accommodation part  413  is also increased through the filter  414  provided in the front part substrate  412 , and the plurality of small holes  412   c . Then, when the inside pressure is more than a predetermined value, the medicine accommodated in the accommodation part  413  is injected from the communication hole  411   a  provided in the front part sheath member  411 .  
         [0196]     Accordingly, the medicine accommodated inside can be directly injected and the cure can be made.  
         [0197]     Further, inversely structured to above description, the body fluid in the organ can be sampled for the inspection. This will be described based on  FIG. 18 . However, because the basic structure is the same as the structure for injecting the medicine as shown in  FIG. 17 , the description for the same structure will be neglected.  
         [0198]     In  FIG. 18 , the most different point from  FIG. 17  is a point that, when the tested subject takes down the capsule type medical device  401 , the bellow part  404  is contracted as in  FIG. 18 (A). Then, in a predetermined organ, the bellow part  404  is stretched as in  FIG. 18 (B). Hereby, the inside space  431  is increased, and the air in the inside space  431  is swelled. Accordingly, the inside pressure of the inside space  431  is reduced, and the inside pressure of the accommodation part  413  is also decreased through a plurality of small holes  412   c  provided in the front part substrate  412  and the filter  414 . Then, when the inside pressure is less than a predetermined value, the body fluid in the organ enters into the accommodation part  413  from the communication hole  411   a.    
         [0199]     Accordingly, the body fluid in an arbitrary organ can be sampled and inspected.  
         [0200]     Hereupon, as the drive part for stretching the bellow part  404 , the conductive high polymer actuator, shape memory alloy, piezo-electric element may also be used other than the micro-mini motor.  
         [0201]     Further, in the case of the structure in which the capsule type medical device injects the medicine or samples the body liquid, the image pick-up apparatus for image picking-up in the organ, may also be provided.  
         [0202]     Further, the capsule type medical device does not have only one of the moving structure as described above, the structure for injecting the medicine, the structure for sampling the body fluid, however, it may also simultaneously have  
         [0000]     two or three of these structures.  
         [0203]     Other than that, in each of above described capsule type medical device  301 ,  401 , although not shown, there is no hinder when the capsule type medical device is taken down, it is desirable that the bellow parts  304 ,  404  are sheathed by the sheath member formed of the material dissolved by the body fluid in the organ. As the material, for example, gelatin formed of the bone of caw, and the skin of pig or oblate formed of agar and farina is used.  
         [0204]     Further, when the electric power is supplied to the power receiving coil provided in the capsule type medical device from the coil arranged outside the body by the electromagnetic induction, the batteries  322 ,  427  are unnecessary.  
         [0205]     Further, the posture sensor is housed in the rear parts  303 ,  403 , and the posture of the capsule type medical device may also be transmitted to the external device by the transmission and reception sections  321 ,  425 .  
         [0206]     Further, it may also be allowable that CPU in which the stretching and contracting motion of the bellow parts  304 ,  404  is written as the program is housed in the capsule type medical device, and the apparatus is automatically moved in the body, the medicine is injected, or the body fluid is sampled.