Abstract:
An ultrasound probe system includes a main body portion, an ultrasound observation portion transmitting ultrasound in a side surface direction of the main body portion and receiving a reflected wave, a distal-end portion provided such that a proximal-end face, on a proximal-end side is adjacent to a distal-end in an axial direction of the main body portion, a sheath portion housing the main body portion inside to be capable of advancing and retracting in the axial direction, a distal-end face arranged at a distal-end of the sheath portion and facing the proximal-end face, a specimen collecting portion provided on the proximal-end face and/or the distal-end face, the specimen collecting portion being formed at an acute angle to separate a specimen from a subject, and an edge portion arranged on the proximal-end face or the distal-end face to cross the entire circumference of the specimen collecting portion to cut the specimen.

Description:
CROSS REFERENCE TO RELATED APPLICATION 
       [0001]    This application is a continuation application of PCT/JP2013/082725 filed on Dec. 5, 2013 and claims benefit of Japanese Application No. 2013-005626 filed in Japan on Jan. 16, 2013, the entire contents of which are incorporated herein by this reference. 
     
    
     BACKGROUND OF THE INVENTION 
       [0002]    1. Field of the Invention 
         [0003]    The present invention relates to an ultrasound probe system including a sheath portion configured to house an elongated main body portion, which is provided with an ultrasound observation portion, to be movable back and forth in an insertion axial direction. 
         [0004]    2. Description of the Related Art 
         [0005]    Japanese Patent Application Laid-Open Publication No. 2004-216159 discloses a method and a configuration of an ultrasound probe system for inserting a sheath into a lumen together with an ultrasound probe in a state in which the ultrasound probe is inserted into the sheath and, after performing ultrasound observation of an examined region in the lumen using an ultrasound observation portion provided at a distal end in an axial direction of the ultrasound probe, pulling out the ultrasound probe from the sheath and, thereafter, inserting the specimen collecting tool into the sheath to collect a specimen, which is a living tissue of the examined region. 
       SUMMARY OF THE INVENTION 
       [0006]    An ultrasound probe system according to an aspect of the present invention includes: a bar-like main body portion; an ultrasound observation portion provided in the main body portion and configured to transmit ultrasound in a side surface direction of the main body portion and receive a reflected wave; a distal end portion provided such that a proximal end face, which is a surface on a proximal end side, is adjacent to a distal end in an axial direction of the main body portion, the distal end portion having a diameter larger than the main body portion; a cylindrical sheath portion having a diameter larger than the main body portion and configured to house the main body portion on an inside thereof to be capable of advancing and retracting in the axial direction; a distal end face arranged at a distal end of the sheath portion and facing the proximal end face; a specimen collecting portion provided on at least one of the proximal end face and the distal end face, an entire circumference of the specimen collecting portion being formed at an acute angle toward the axial direction in order to separate a specimen from a subject in an annular shape; and an edge portion arranged on the proximal end face or the distal end face to cross the entire circumference of the specimen collecting portion in order to cut the annular specimen collected by the specimen collecting portion. 
     
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         [0007]      FIG. 1  is a partial sectional view showing, in a closed state of a specimen collection port, a distal end side in an axial direction of an ultrasound probe system in a first embodiment; 
           [0008]      FIG. 2  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in an open state of the specimen collection port shown in  FIG. 1 ; 
           [0009]      FIG. 3  is a perspective view showing a distal end side in the axial direction of a sheath portion shown in  FIG. 1  together with an edge portion in enlargement; 
           [0010]      FIG. 4  is a partial sectional view showing positions in the axial direction in the closed state of the specimen collection port shown in  FIG. 1  in respective operation members of the sheath portion and a main body portion provided in a halfway position in the axial direction of the ultrasound probe system shown in  FIG. 1 ; 
           [0011]      FIG. 5  is a partial sectional view showing positions in the axial direction in the open state of the specimen collection port shown in  FIG. 2  in the respective operation members of the sheath portion and the main body portion shown in  FIG. 4 ; 
           [0012]      FIG. 6  is a partial sectional view showing a state in which the positions in the axial direction of the respective operation members of the sheath portion and the main body portion shown in  FIG. 5  are fixed in the closed state of the specimen collection port shown in  FIG. 2 ; 
           [0013]      FIG. 7  is a plan view of an O-shaped ring stop member viewed from a VII direction in  FIG. 6 ; 
           [0014]      FIG. 8  is a diagram schematically showing a state in which the ultrasound probe system is inserted into one lumen having a narrow portion due to a lesion part and the other lumen without a lesion part in a branch portion of a pulmonary periphery in a subject; 
           [0015]      FIG. 9  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration in which the distal end portion is detachable from the main body portion shown in  FIG. 1 ; 
           [0016]      FIG. 10  is a partial sectional view showing, in a closed state of a specimen collection port, a distal end side in an axial direction of an ultrasound probe system in a second embodiment; 
           [0017]      FIG. 11  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in an open state of the specimen collection port shown in  FIG. 10 ; 
           [0018]      FIG. 12  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing, in the closed state of the specimen collection port, a modification in which a step portion is provided in a part on an inner circumferential surface of a sheath portion facing a housing portion shown in  FIG. 10 ; 
           [0019]      FIG. 13  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in the open state of the specimen collection port shown in  FIG. 12 ; 
           [0020]      FIG. 14  is a partial sectional view schematically showing a connector provided at a proximal end of the ultrasound probe system shown in  FIG. 10 ; 
           [0021]      FIG. 15  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration of a modification excluding an edge portion from a housing portion of the ultrasound probe system shown in  FIG. 10 ; 
           [0022]      FIG. 16  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration of a modification in which a plurality of grooves along the axial direction are formed along a circumferential direction on an inner circumferential surface of the sheath portion of the ultrasound probe system shown in  FIG. 10 ; 
           [0023]      FIG. 17  is a sectional view of the sheath portion taken along line XVII-XVII in  FIG. 16 ; 
           [0024]      FIG. 18  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration of a modification in which a plurality of grooves along the axial direction are formed along the circumferential direction on an outer circumferential surface of the main body portion of the ultrasound probe system shown in  FIG. 10 ; 
           [0025]      FIG. 19  is a sectional view of the sheath portion and the main body portion taken along line XIX-XIX in  FIG. 18 ; and 
           [0026]      FIG. 20  is a diagram schematically showing an endoscope system including the ultrasound probe system in the first and second embodiments. 
       
    
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
       [0027]    Embodiments of the present invention are explained below with reference to the drawings. 
       First Embodiment 
       [0028]      FIG. 1  is a partial sectional view showing, in a closed state of a specimen collection port, a distal end side in an axial direction of an ultrasound probe system in the present embodiment.  FIG. 2  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in an open state of the specimen collection port shown in  FIG. 1 . 
         [0029]      FIG. 3  is a perspective view showing a distal end side in the axial direction of a sheath portion shown in  FIG. 1  together with an edge portion in enlargement.  FIG. 4  is a partial sectional view showing positions in the axial direction in the closed state of the specimen collection port shown in  FIG. 1  in respective operation members of the sheath portion and a main body portion provided in a halfway position in the axial direction of the ultrasound probe system shown in  FIG. 1 .  FIG. 5  is a partial sectional view showing positions in the axial direction in the open state of the specimen collection port shown in  FIG. 2  in the respective operation members of the sheath portion and the main body portion shown in  FIG. 4 . 
         [0030]    Further,  FIG. 6  is a partial sectional view showing a state in which the positions in the axial direction of the respective operation members of the sheath portion and the main body portion shown in  FIG. 5  are fixed in the closed state of the specimen collection port shown in  FIG. 2 .  FIG. 7  is a plan view of an O-shaped ring stop member viewed from a VII direction in  FIG. 6 . 
         [0031]    As shown in  FIG. 1  and  FIG. 2 , an ultrasound probe system  1  is, for example, inserted through a not-shown treatment instrument insert-through channel formed in an insertion portion  122   a  of an endoscope  122  (see  FIG. 20  for both of the insertion portion  122   a  and the endoscope  122 ) or independently inserted into a subject. The ultrasound probe system  1  includes a bar-like, that is, elongated tubular main body portion  2  inserted into the subject via the treatment instrument insert-through channel or directly. 
         [0032]    Note that the main body portion  2  may be rigid or may be deformable and, for example, may be formed of a material having elasticity. Specific examples of the material having elasticity include polyamide resin. The main body portion  2  is formed of a material having higher stretchability in an axial direction E of the main body portion  2  than a below-mentioned sheath portion  5 . 
         [0033]    On a distal end side in the axial direction E in an inside  2   i  of the main body portion  2 , an ultrasound observation portion  13  that transmits ultrasound in a side surface direction S crossing the axial direction E of the main body portion  2  to thereby obtain an ultrasound image in a subject is provided. 
         [0034]    The ultrasound observation portion  13  is configured from a ring-like ultrasound transducer. The ultrasound observation portion  13  is fixed to the distal end side in the axial direction E on the inside  2   i  of the main body portion  2  by an adhesive  11  and fixed to a substrate  14  on which an IC  12  is mounted. 
         [0035]    On the inside  2   i  of the main body portion  2 , an ultrasound transducer cable  15  is extended to a back in the axial direction E from the substrate  14 . An extending end of the ultrasound transducer cable  15  is electrically connected to an electric connector  51  in a below-mentioned connector  40  (see  FIG. 14  for both of the electric connector  51  and the connector  40 ) fixed to a proximal end in the axial direction E of the main body portion  2 . The ultrasound transducer cable  15  is a cable for transmitting, to the ultrasound observation portion  13 , an electric pulse signal outputted from an ultrasound observation device  123  (see  FIG. 20 ) to which the electric connector  51  is connected. 
         [0036]    A distal end portion  3  having a diameter larger than the main body portion  2  is provided at a distal end in the axial direction E of the main body portion  2 . In the distal end portion  3 , a proximal end face  3   m  is formed as an inclined surface inclined further backward in the axial direction E toward an outer side in a radial direction from a part on an inner side having substantially a same diameter as an outer circumferential surface  2   g  at the distal end in the axial direction E of the main body portion  2 . 
         [0037]    Therefore, in the distal end portion  3 , a proximal end  3   k  in the axial direction E, which is an outer circumference end portion of the proximal end face  3   m , is formed at an acute angle by an outer circumferential surface on a proximal end side in the axial direction E of the distal end portion  3  and the proximal end face  3   m . That is, the proximal end  3   k  is formed as an acute edge portion. 
         [0038]    The proximal end  3   k  functions as a specimen collecting portion configured to collect a specimen in an examined region in the subject. Note that the specimen collecting portion may be separated from the proximal end  3   k . The specimen collecting portion may be fixed to the proximal end  3   k  by bonding or insert molding. 
         [0039]    A distal end face  3   s  at a distal end in the axial direction of the distal end portion  3  is formed as, for example, a curved surface. In  FIG. 1 , the distal end portion  3  has a substantially bullet-like shape in section. In the present embodiment, the distal end portion  3  is formed integrally with the main body portion  2 . 
         [0040]    An outer circumference of the main body portion  2  is covered with, along the axial direction E, the sheath portion  5  having a diameter larger than the main body portion  2  and having an outer diameter substantially the same as an outer diameter on the proximal end side in the axial direction E of the distal end portion  3 . Note that the sheath portion  5  is inserted into the subject having a plurality of curved portions. Therefore, in order to secure insertability, the sheath portion  5  is formed of resin having flexibility and having biocompatibility. Note that examples of the resin forming the sheath portion  5  include polyethylene, fluorocarbon resin, and PEEK. On a distal end side in the axial direction E of the sheath portion  5 , a part opposed to the ultrasound observation portion  13  has ultrasound permeability. 
         [0041]    The sheath portion  5  houses the main body portion  2  on an inside to be movable back and forth in the axial direction E. As shown in  FIG. 1  to  FIG. 3 , a distal end face  5   m  at a distal end in the axial direction E as an inclined surface further inclined backward in the axial direction E toward an inner side in a radial direction from an outer circumferential surface of the sheath portion  5 . 
         [0042]    Therefore, in the sheath portion  5 , a distal end  5   s  in the axial direction E, which is an outer circumference end portion of the distal end face  5   m , is formed at an acute angle by an outer circumferential surface on the distal end side in the axial direction E of the sheath portion  5  and the distal end face  5   m . That is, the distal end  5   s  is formed as an acute edge portion. 
         [0043]    The distal end  5   s  functions as a specimen collecting portion configured to collect a specimen in an examined region in the subject. Note that the specimen collecting portion may be separate from the distal end  5   s . Only the specimen collecting portion may be fixed to the distal end  5   s  by bonding or insert molding. 
         [0044]    Note that, as explained above, the specimen collecting portion is the proximal end  3   k  of the distal end portion  3  and the distal end  5   s  of the sheath portion  5  or being provided at the proximal end  3   k  and the distal end  5   s . However, the specimen collecting portion may be any one of the proximal end  3   k  and the distal end  5   s  itself or may be provided at any one of the proximal end  3   k  and the distal end  5   s.    
         [0045]    The sheath portion  5  is slid, whereby the distal end  5   s  of the sheath portion  5  comes into contact with the proximal end  3   k  of the distal end portion  3  as shown in  FIG. 1 . In this state, a below-mentioned specimen collection port  150  (see  FIG. 2 ) changes to a closed state. 
         [0046]    When the main body portion  2  is moved further forward in the axial direction E than the sheath portion  5  from a position where the distal end  5   s  shown in  FIG. 1  comes into contact with the proximal end  3   k  of the distal end portion  3  or when the sheath portion  5  is moved further backward in the axial direction E than the main body portion  2 , as shown in  FIG. 2 , the proximal end  3   k  separates from the distal end  5   s  in the axial direction E. At this point, as shown in  FIG. 2 , the specimen collection port  150  is opened between the proximal end  3   k  and the distal end  5   s.    
         [0047]    The specimen collection port  150  is an introduction port for, when the ultrasound probe system  1  is inserted into a narrow portion  81   k  (see  FIG. 8 ) of a lumen (e.g., pulmonary periphery bronchi)  81  due to a lesion part  85 , which is an examined region in the subject, and the specimen collection port  150  changes to an open state in which the proximal end  3   k  separates from the distal end  5   s  in the axial direction E as shown in  FIG. 2 , introducing a specimen of the lesion part  85  in the narrow portion  81   k  to a vicinity of the outer circumferential surface  2   g  of the main body portion  2  in the sheath portion  5 . 
         [0048]    Note that, in a state in which the specimen is introduced to the vicinity of the outer circumferential surface  2   g  of the main body portion  2  via the specimen collection port  150 , as shown in  FIG. 1 , the main body portion  2  is moved backward in the axial direction E or the sheath portion  5  is moved forward in the axial direction E to a position where the specimen collection port  150  changes to the closed state in which the distal end  5   s  comes into contact with the proximal end  3   k , whereby the specimen is sandwiched by the distal end  5   s  and the proximal end  3   k . A part of the specimen is cut by at least one of the distal end  5   s  and the proximal end  3   k.    
         [0049]    As explained above, since the sheath portion  5  is formed in a diameter larger than the main body portion  2 , a space  8  is formed between an inner circumferential surface  5   n  of the sheath portion  5  and the outer circumferential surface  2   g  of the main body portion  2 . Note that in the space  8 , for example, saline functioning as an ultrasound transmission medium is filled from a below-mentioned pipe sleeve  25  (see  FIG. 4 ). 
         [0050]    As shown in  FIG. 2 , in the open state of the specimen collection port  150 , the saline leaks from the space  8 . However, instead, mucus or the like in the subject enters the space  8 , whereby the entered liquid functions as the ultrasound transmission medium. 
         [0051]    Note that, when an interval in a radial direction in the space  8  is narrow, that is, when an interval between the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5  in the radial direction is narrow, outside the subject, in the open state of the specimen collection port  150  shown in  FIG. 2 , the saline may be injected from the specimen collection port  150  into the space  8  using a capillary phenomenon. The capillary phenomenon tends to occur when hydrophilic treatment is applied to the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0052]    Further, on a distal end side in the axial direction E of the space  8 , a housing portion  8   y  is provided that has a predetermined length from the distal end  5   s  of the sheath portion  5  along the axial direction E and in which a specimen collected by at least one of the proximal end  3   y  and the distal end  5   s  is housed. 
         [0053]    Note that a part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  may be subjected to surface treatment to have higher hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . In other words, the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  may have a higher contact angle than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0054]    More specifically, hydrophobic coating may be applied to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y . Hydrophilic coating may be applied to the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0055]    Note that examples of the hydrophobic coating include coating performed using a fluorine-based coating material. Examples of the hydrophilic coating include coating by bioinspire, PEG, and other hydrophilic polymers. 
         [0056]    Naturally, it is also possible that coating is not performed and only the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  is formed of fluorine-based resin such as PTFE, PE, or the like, whereby the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  has higher hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0057]    When the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  has higher hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5  in this way, since the specimen contains fat as a main component, the specimen tends to adhere to a hydrophobic material. That is, the specimen tends to adhere to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y.    
         [0058]    Therefore, if the specimen is attracted to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y , the specimen is housed in an attracted state to be opposed to the specimen collection port  150 . Therefore, after surgery, the specimen can be easily extracted by tweezers or the like via the specimen collection port  150 . 
         [0059]    This is because, if the specimen adheres to the inner circumferential surface  5   n  of the sheath portion  5  in the housing portion  8   y , since the inner circumferential surface  5   n  is located further on the specimen collection port  150  side than the outer circumferential surface  2   g  of the main body portion  2 , after surgery, it is difficult to extract the specimen via the specimen collection port  150 . 
         [0060]    Further, as shown in  FIG. 1  to  FIG. 3 , in the housing portion  8   y , more specifically, on a distal end side in the axial direction E of the distal end face  5   m  and the inner circumferential surface  5   n  of the sheath portion  5 , an edge portion  7  having a predetermined length E 1  from the distal end  5   s  of the sheath portion  5  along the axial direction E and configured to cut a specimen housed in the housing portion  8   y  is provided. 
         [0061]    The edge portion  7  cuts, for example, a ring-like specimen housed in the housing portion  8   y  and forms the specimen, for example, in a C shape to make it easy to extract, after surgery, the specimen from the housing portion  8   y  using tweezers or the like via the specimen collection port  150 . 
         [0062]    This is because, since the specimen collected by being nipped by the proximal end  3   k  and the distal end  5   s  is housed in a ring shape in the housing portion  8   y , if the specimen keeps the ring shape, after surgery, it is difficult to extract the specimen via the specimen collection port  150 . Alternatively, this is because, if the specimen keeps the ring shape, when the specimen is extracted, the specimen has to be cut by scissors or the like in a state in which the specimen is grasped by the tweezers and extraction work is complicated. 
         [0063]    Note that, in the present embodiment, for example, one edge portion  7  is provided in the housing portion  8   y . However, a plurality of the edge portions  7  may be provided along a circumferential direction of the housing portion  8   y.    
         [0064]    As shown in  FIG. 4 , in a halfway position in the axial direction E of the ultrasound probe system  1 , more specifically, in a position further forward in the axial direction E than the below-mentioned connector  40  (see  FIG. 14 ) in the main body portion  2 , an operation member  21  of the main body portion  2  configured to move the main body portion  2  forward and backward in the axial direction E on an inside of the sheath portion  5  is fixed to the main body portion  2  by bonding, welding, or the like. Note that a position of the operation member  21  shown in  FIG. 4  indicates a position where the specimen collection port  150  is in the closed state in which the proximal end  3   k  and the distal end  5   s  come into contact with each other shown in  FIG. 1 . 
         [0065]    The operation member  21  is a member located outside the subject and operated by an examiner when the ultrasound probe system  1  is inserted into the subject. A finger hook  22  for operation, on which a finger of the examiner is hooked, is provided at a proximal end in the axial direction E of the operation member  21 . Note that the finger hook  22  may be provided integrally with the operation member  21  or may be separate from the operation member  21  and fixed to the operation member  21 . 
         [0066]    Therefore, in a state in which the finger is hooked on the finger hook  22 , when the examiner moves the operation member  21  forward in the axial direction E from the position shown in  FIG. 4  to a position shown in  FIG. 5 , the proximal end  3   k  of the distal end portion  3  separates from the distal end  5   s  of the sheath portion  5  forward in the axial direction E. Consequently, as shown in  FIG. 2 , the specimen collection port  150  changes to the open state. 
         [0067]    On the contrary, when the operation member  21  is moved backward in the axial direction E from the position shown in  FIG. 5  to the position shown in  FIG. 4 , the proximal end  3   k  of the distal end portion  3  comes into contact with the distal end  5   s  of the sheath portion  5 . Consequently, as shown in  FIG. 1 , the specimen collection port  150  changes to the closed state. 
         [0068]    As shown in  FIG. 4  and  FIG. 5 , an operation member  23  of the sheath portion  5  is fixed to an outer circumference at a proximal end of the sheath portion  5  by bonding, welding, or the like. 
         [0069]    The operation member  23  is a member located outside the subject and operated by the examiner when the ultrasound probe system  1  is inserted into the subject and is a member configured to move the sheath portion  5  back and forth in the axial direction E. 
         [0070]    At a proximal end in the axial direction E of the operation member  23 , a finger hook  24  for operation, on which the finger of the examiner is hooked, is provided. Note that the finger hook  24  may be provided integrally with the operation member  23  or may be separate from the operation member  23  and fixed to the operation member  23  by bonding, welding, screw fastening, or the like. 
         [0071]    Further, a through-hole  23   h  piercing through the operation member  23  in a radial direction is formed in a part further forward in the axial direction E than a part where the finger hook  24  is provided on a proximal end side in the axial direction E of the operation member  23  and further backward in the axial direction E than the proximal end of the sheath portion  5 . In the through-hole  23   h , a pipe sleeve  25  for supplying fluid to the space  8  or discharging the fluid from the space  8  via the through-hole  23   h  is provided. Note that the pipe sleeve  25  has, for example, a lure pipe sleeve shape. 
         [0072]    For example, when the saline is supplied to the space  8  or when liquid or gas is supplied to the space  8  when the specimen is removed from the housing portion  8   y , a fluid supplying device is attached to the pipe sleeve  25 . Besides, when the space  8  is decompressed to allow the specimen to enter the housing portion  8   y  in the open state of the specimen collection port  150  or when the specimen housed in the housing portion  8   y  is sucked and extracted via the pipe sleeve  25 , a suction device is attached to the pipe sleeve  25 . 
         [0073]    An O-shaped ring  27  is provided further backward in the axial direction E than the through-hole  23   h  between an inner circumferential surface on the proximal end side in the axial direction E of the operation member  23  and an outer circumferential surface of the operation member  21 . 
         [0074]    The O-shaped ring  27  is a member configured to prevent the fluid in the space  8  from being discharged from the proximal end side in the axial direction E of the operation member  23  and prevent liquid on an outside from suddenly entering the space  8 . 
         [0075]    On an inner circumferential surface at the proximal end in the axial direction E of the operation member  23 , a stopper member  28  for the O-shaped ring  27  having a ring shape is fixed to the operation member  23  by screwing, bonding, press fitting, or the like. 
         [0076]    Note that, as shown in  FIG. 7 , a convex portion  28   t  may be provided on an inner circumferential surface  28   n  of the stopper member  28 . As shown in  FIG. 6 , two concave portions  21   p  and  21   q  that are separated along the axial direction E and in which the convex portion  28   t  can be fit may be provided in a position opposed to the convex portion  28   t  on an outer circumferential surface  21   g  of the operation member  21 . 
         [0077]    With such a configuration, when the convex portion  28   t  is fit in the concave portion  21   p  as shown in  FIG. 6 , as shown in  FIG. 1 , the operation member  21 , that is, the main body portion  2  is fixed in the position where the specimen collection port  150  is in the closed state in which the proximal end  3   k  comes into contact with the distal end  5   s . When the convex portion  28   t  is fit in the concave portion  21   q , as shown in  FIG. 2 , the operation member  21 , that is, the main body portion  2  is fixed in the position where the specimen collection port  150  is in the open state in which the proximal end  3   k  separates from the distal end  5   s.    
         [0078]    Next, action in the present embodiment is explained with reference to  FIG. 1  to  FIG. 7  and  FIG. 8 .  FIG. 8  is a diagram schematically showing a state in which the ultrasound probe system is inserted into one lumen having a narrow portion due to a lesion part and the other lumen without a lesion part in a branch portion of a pulmonary periphery in a subject. 
         [0079]    First, outside the subject, the examiner inserts the main body portion  2  from the distal end side in the axial direction E of the sheath portion  5  into the inside of the sheath portion  5  along the axial direction E. Note that this work may be substituted by covering an outer circumference of the main body portion  2  with the sheath portion  5  from a proximal end side in the axial direction E of the main body portion  2  along the axial direction E. 
         [0080]    Subsequently, the examiner injects the saline into the space  8 . Note that as explained above, this injection work may be performed from the pipe sleeve  25  or may be performed from the specimen collection port  150  making use of the capillary phenomenon. 
         [0081]    Thereafter, as shown in  FIG. 6 , the examiner fits the stopper member  28  in the concave portion  21   p  of the operation member  21  to thereby fix a position in the axial direction E of the main body portion  2  with respect to the sheath portion  5  in the closed state of the specimen collection port  150  shown in  FIG. 1  in which the distal end  5   s  comes into contact with the proximal end  3   k.    
         [0082]    Subsequently, for example, when the examiner performs collection of a specimen of a small-diameter pulmonary periphery, into which the insertion portion  122   a  of the endoscope  122  cannot be inserted, using the ultrasound probe system  1 , the examiner inserts the insertion portion  122   a  of the endoscope  122  into a bronchus via an oral cavity and, thereafter, after inserting the insertion portion  122   a  to a vicinity of an entrance of a pulmonary periphery bronchus, inserts, from the distal end side in the axial direction E, the ultrasound probe system  1  into the treatment instrument insert-through channel of the insertion portion  122   a  of the endoscope  122  from a treatment instrument insertion port  122   e  (see  FIG. 20 ) of the treatment instrument insert-through channel provided in an operation portion  122   b  (see  FIG. 20 ) of the endoscope  122 . 
         [0083]    Thereafter, after projecting a distal end side in the axial direction E of the ultrasound probe system  1  from a distal end opening of the insertion portion  122   a  of the treatment instrument insert-through channel, under X-ray observation, the examiner inserts the ultrasound probe system  1  into a target pulmonary periphery bronchus  80  as shown in  FIG. 8  while checking a position of the distal end side in the axial direction E of the ultrasound probe system  1 . 
         [0084]    In this case, as explained above, since the stopper member  28  is fit in the concave portion  21   p , that is, positions of the main body portion  2  and the sheath portion  5  are fixed, the closed state of the specimen collection port  150  is maintained. Therefore, since the proximal end  3   k  is in close contact with the distal end  5   s , at least one of the proximal end  3   k  and the distal end  5   s  does not shave a wall surface of the pulmonary periphery bronchus  80 , with which the ultrasound probe system  1  comes into contact, according to the insertion of the ultrasound probe system  1 . 
         [0085]    Since the positions of the main body portion  2  and the sheath portion  5  are fixed, the closed state of the specimen collection port  150  is maintained. Therefore, a situation is prevented in which, according to the insertion of the ultrasound probe system  1 , the specimen collection port  150  is opened by the wall surface of the pulmonary periphery bronchus  80 , with which the ultrasound probe system  1  comes into contact, and insertability of the ultrasound probe system  1  is deteriorated. Besides, as explained above, the wall surface of the pulmonary periphery bronchus  80  is prevented from being shaved by the distal end  5   s  and the proximal end  3   k.    
         [0086]    After inserting the ultrasound probe system  1  into the pulmonary periphery bronchus  80 , the examiner searches for a lesion part  85  while performing ultrasound observation using the ultrasound observation portion  13 . 
         [0087]    In this case, when the examiner can recognize from an observation image of the ultrasound observation portion  13  that, as shown in  FIG. 8 , the distal end side in the axial direction E of the ultrasound probe system  1  is inserted into a lumen  82  without the lesion part  85  from a branch of the pulmonary periphery bronchus  80 , more specifically, when the examiner recognizes from the observation image that the distal end side in the axial direction E of the ultrasound probe system  1  is not inserted into a center of the lesion part  85 , the examiner pulls out the distal end side in the axial direction E of the ultrasound probe system  1  from the lumen  82  and inserts the distal end side in the axial direction E of the ultrasound probe system  1  into another lumen  81 . 
         [0088]    As a result, when the examiner can recognize from the observation image of the ultrasound observation portion  13  that, as shown in  FIG. 8 , the distal end side in the axial direction E of the ultrasound probe system  1  is located in the center of the lesion part  85  from the branch of the pulmonary periphery bronchus  80  and inserted into the lumen  81  in which a narrow portion  81   k  is formed by the lesion part  85 , the examiner locates a distal end in the axial direction E of the ultrasound probe system  1  on an examiner&#39;s side about 1 cm from the center of the lesion part  85 . 
         [0089]    Thereafter, the examiner moves the main body portion  2  forward in the axial direction E by, about 1 cm from a position shown in  FIG. 6  to a position shown in  FIG. 5  using the operation member  21 . As a result, the diameter of the narrow portion  81   k  is expanded by the distal end portion  3  and, as shown in  FIG. 2 , the proximal end  3   k  in contact with the distal end  5   s  moves forward in the axial direction E, whereby the specimen collection port  150  is opened. 
         [0090]    According to the opening of the specimen collection port  150 , since the narrow portion  81   k  is formed in the lumen  81  in which the lesion part  85  is formed, a part of the lesion part  85  is introduced into the sheath portion  5  to a vicinity of the outer circumferential surface  2   g  on a distal end side in the axial direction of the main body portion  2  via the specimen collection port  150 . In this case, if the suction device is attached to the pipe sleeve  25  to decompress the space  8 , the part of the lesion part  85  easily enters the sheath portion  5  more surely. 
         [0091]    According to the opening of the specimen collection port  150 , the ultrasound observation portion  13  moves forward about 1 cm in the axial direction E. However, in most cases, 2 cm or more of the lesion part  85  is present in the axial direction E, the ultrasound observation portion  13  does not lose sight of the lesion part  85  according to the movement. 
         [0092]    Thereafter, after confirming from the observation image that a lesion part is rendered, the examiner adjusts a position in the axial direction E of the main body portion  2  or the sheath portion  5  according to necessity while observing the observation image in the ultrasound observation portion  13 . 
         [0093]    Subsequently, in order to collect a large volume of specimen of the lesion part  85 , the examiner moves the main body portion  2  back and forth in the axial direction E or moves the sheath portion  5  back and forth in the axial direction E using the operation member  23 . 
         [0094]    As a result, a living tissue of the lesion part  85  is housed in the housing portion  8   y  via the specimen collection port  150  as a specimen by at least one of the distal end  5   s  and the proximal end  3   k . Note that, in this case, when the suction device is attached to the pipe sleeve  25  to decompress the space  8 , the specimen can be more easily housed in the housing portion  8   y . Note that when the space  8  is decompressed, a collection quantity of specimen can be increased. Further, it is possible to collect specimen even in a bronchus with a slightly larger inner lumen. 
         [0095]    A ring-like specimen housed in the housing portion  8   y  is partially cut in the edge portion  7  and formed in, for example, a C shape. If, for example, hydrophobic coating is applied to a part on the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  as explained above, the specimen is attracted to the part on the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y.    
         [0096]    Thereafter, the examiner moves the main body portion  2  backward in the axial direction E until the stopper member  28  fits in the concave portion  21   p  and pulls out the ultrasound probe system  1  from the treatment instrument insert-through channel of the endoscope  122 , that is, pulls out the ultrasound probe system  1  to an outside of the subject. 
         [0097]    Subsequently, on the outside of the subject, the examiner moves the main body portion  2  forward in the axial direction E again or moves the sheath portion  5  backward in the axial direction E to thereby change the specimen collection port  150  to the open state as shown in  FIG. 2 . Thereafter, the examiner extracts, using the tweezers or the like, via the specimen collection port  150 , the specimen housed in the housing portion  8   y  on the outer circumferential surface  2   g  of the main body portion  2  and cut by the edge portion  7 . 
         [0098]    Note that the extraction of the specimen may be performed by immersing the distal end side in the axial direction E of the ultrasound probe system  1  in liquid to thereby drop the specimen into the liquid. Further, the extraction of the specimen may be performed by supplying the liquid from the pipe sleeve  25  to the space  8  or may be performed by sucking the liquid from the pipe sleeve  25  via the space  8 . 
         [0099]    Thereafter, after the extraction of the specimen ends, the examiner moves the main body portion  2  backward in the axial direction E until the stopper member  28  fits in the concave portion  21   p  or moves the sheath portion  5  forward in the axial direction E to bring the proximal end  3   k  into contact with the distal end  5   s . That is, the examiner changes the specimen collection port  150  to the closed state as shown in  FIG. 1 . 
         [0100]    Finally, the examiner discards the sheath portion  5  and the main body portion  2 . 
         [0101]    As explained above, in the present embodiment, during the ultrasound observation of the lesion part  85  by the ultrasound observation portion  13 , the main body portion  2  is moved back and forth in the axial direction E or the sheath portion  5  is moved back and forth in the axial direction E. Consequently, it is possible to collect the specimen of the lesion part  85  using at least one of the proximal end  3   k  of the distal end portion  3  and the distal end  5   s  of the sheath portion  5 . 
         [0102]    Therefore, during the ultrasound observation of the lesion part  85  by the ultrasound observation portion  13 , it is possible to collect the specimen of the lesion part  85  surely and with high position accuracy. 
         [0103]    In the present embodiment, the edge portion  7  configured to cut the specimen housed in the housing portion  8   y  is provided in the housing portion  8   y.    
         [0104]    Further, the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  has more hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0105]    Therefore, the specimen housed in the housing portion  8   y  is cut by the edge portion  7 . The specimen adheres to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y . Consequently, it is possible to easily collect the specimen from the housing portion  8   y  via the specimen collection port  150 . 
         [0106]    Therefore, certainty of diagnostic properties for a lesion part is improved. A reduction in an examination time and reexamination are unnecessary. Therefore, it is possible not only to reduce burdens on the examiner and the subject but also, for example, to select an appropriate method of treatment. 
         [0107]    Consequently, it is possible to provide the ultrasound probe system  1  including a configuration with which collection of a specimen of an examined region can be performed during ultrasound observation and the collected specimen is easily extracted. 
         [0108]    Note that a modification is explained below with reference to  FIG. 9 .  FIG. 9  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration in which the distal end portion is detachable from the main body portion shown in  FIG. 1 . 
         [0109]    In the present embodiment explained above, the distal end portion  3  is formed integrally with the main body portion  2 . However, the distal end portion  3  is not limited to this and may be provided separately from the main body portion  2 . 
         [0110]    More specifically, as shown in  FIG. 9 , a small-diameter portion  2   w , on an outer circumferential surface of which a screw  2   r  is formed, is formed at the distal end in the axial direction E of the main body portion  2 . At the distal end portion  3 , a concave groove  3   x  along the axial direction E, in which the small-diameter portion  2   w  can be fit, is formed in a center in a radial direction of the distal end portion  3 . Further, a screw groove  3   r , with which the screw  2   r  is screwed, is formed on an inner circumferential surface of the concave groove  3   x . On the outer circumferential surface of the distal end portion  3 , a rotation groove  3   v  for rotating the distal end portion  3  in order to fix the distal end portion  3  to the small-diameter portion  2   w  is formed. 
         [0111]    Therefore, the distal end portion  3  can be attached to a distal end in the axial direction E of the main body portion  2  simply by fitting the small-diameter portion  2   w  in the concave groove  3   x , rotating the distal end portion  3  in one direction using the rotation groove  3   v , and screwing the screw  2   r  in the screw groove  3   r . The distal end portion  3  can be pulled out from the distal end in the axial direction E of the main body portion  2  simply by rotating the distal end portion  3  in the other direction using the rotation groove  3   v  and removing the small-diameter portion  2   w  from the concave groove  3   x.    
         [0112]    With such a configuration, since the distal end portion  3  including the proximal end  3   k  configured to collect a specimen can be removed from the main body portion  2 . Therefore, if the distal end portion  3  is removed, an outer surface of the main body portion  2  can be cleaned, disinfected, and sterilized. Therefore, the main body portion  2  can be used again. According to a purpose, it is possible to mount, on the main body portion  2 , a plurality of kinds of the distal end portion  3  having different angles of the proximal end  3   k.    
         [0113]    Note that the other effects are the same as the effects in the first embodiment. 
       Second Embodiment 
       [0114]      FIG. 10  is a partial sectional view showing, in a closed state of a specimen collection port, a distal end side in an axial direction of an ultrasound probe system in the present embodiment.  FIG. 11  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in an open state of the specimen collection port shown in  FIG. 10 . 
         [0115]      FIG. 12  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing, in the closed state of the specimen collection port, a modification in which a step portion is provided in a part on an inner circumferential surface of a sheath portion facing a housing portion shown in  FIG. 10 .  FIG. 13  is a partial sectional view showing the distal end side in the axial direction of the ultrasound probe system in the open state of the specimen collection port shown in  FIG. 12 .  FIG. 14  is a partial sectional view schematically showing a connector provided at a proximal end of the ultrasound probe system shown in  FIG. 10 . 
         [0116]    Compared with the ultrasound probe system in the first embodiment shown in  FIG. 1  to  FIG. 8 , a configuration of the ultrasound probe system in the second embodiment is different in that an ultrasound observation portion  33  is provided movably back and forth in the axial direction in the main body portion  2 . 
         [0117]    Therefore, only the difference is explained. Components same as the components in the first embodiment are denoted by the same reference numerals and signs and explanation of the components is omitted. 
         [0118]    As shown in  FIG. 10  and  FIG. 11 , in the present embodiment, on the inside  2   i  of the main body portion  2 , the ultrasound observation portion  33  that transmits ultrasound in the side surface direction S of the main body portion  2  to thereby obtain an ultrasound image in a subject is provided to be movable back and forth in the axial direction E. 
         [0119]    More specifically, the ultrasound observation portion  33  is provided at a distal end in the axial direction E of an ultrasound probe  31  housed to be movable back and forth in the axial direction E on the inside  2   i  of the main body portion  2 . That is, the ultrasound probe  31  including the ultrasound observation portion  33  is provided to be not fixed to the main body portion  2 . 
         [0120]    More specifically, the ultrasound probe  31  is configured from a mechanical radial scanning probe. 
         [0121]    The ultrasound probe  31  includes the ultrasound observation portion  33  located at the distal end in the axial direction E and configured from a single ultrasound transducer, a housing  36  configured to retain the ultrasound observation portion  33 , and the ultrasound transducer cable  15  extended backward in the axial direction E from the ultrasound observation portion  33  to the below-mentioned connector  40  (see  FIG. 14 ) and configured to transmit, to the ultrasound observation portion  33 , an electric pulse signal outputted from the below-mentioned ultrasound observation device  123  (see  FIG. 20 ). 
         [0122]    The ultrasound probe  31  includes a flexible shaft  35  including the ultrasound transducer cable  15  and extended backward in the axial direction E from the housing  36 . The flexible shaft  35  gives rotation power to the housing  36 . That is, the ultrasound observation portion  33  rotates together with the housing  36  with the rotation power given by the flexible shaft  35 . 
         [0123]    As shown in  FIG. 14 , in the connector  40  provided at the proximal end in the axial direction E of the ultrasound probe system  1 , for example, in a connector cover  48  formed of resin, a proximal end in the axial direction E of the flexible shaft  35  is connected to a connector main body  49  via a rotation transmission shaft  44  and a bearing  46  prevented from coming off the connector cover  48  by a fixing pin  47 . When an electric connector  51  and rotation transmission pins  52  extending from the connector main body  49  are connected to the ultrasound observation device  123 , a rotation driving force is transmitted to the flexible shaft  35  from a driving source provided in the ultrasound observation device  123 . Note that the connector main body  49  is fixed to the connector cover  48  by the fixing pin  47 . 
         [0124]    In the connector  40 , a shield cover  50  for noise reduction formed of metal such as stainless steel or a copper alloy is provided between the connector cover  48  and the connector main body  49 . 
         [0125]    The rotation transmission shaft  44  is in contact with an inner circumferential surface of the connector cover  48  via an O-shaped ring  45 . A sheath fixing ring  43  is pivotably screwed with a screw formed on an outer circumference on a distal end side in the axial direction E of the connector cover  48 . 
         [0126]    On an inside of the sheath fixing ring  43 , a sheath fixing pipe sleeve  41 , to which the proximal end in the axial direction E of the main body portion  2  is fixed, is provided. A rubber ring  42  is provided between an outer circumference of the sheath fixing pipe sleeve  41  and an inner circumference of the sheath fixing ring  43 . 
         [0127]    The sheath fixing ring  43  compresses the rubber ring  42  in a radial direction according to rotation. When the rubber ring  42  is compressed in the radial direction, an inner diameter of the rubber ring  42  decreases and the rubber ring  42  comes into contact with an outer circumferential surface of the sheath fixing pipe sleeve  41 . Consequently, a position at the proximal end in the axial direction E of the main body portion  2  is fixed. 
         [0128]    Note that, although not shown in the figure, in the present embodiment, as in the first embodiment, as shown in  FIG. 4  and  FIG. 5 , the operation member  21  configured to move the main body portion  2  back and forth in the axial direction E, and the operation member  23  configured to move the sheath portion  5  back and forth in the axial direction E, is provided further forward in the axial direction E than the connector  40  in a halfway position in the axial direction E of the ultrasound probe system  1 . 
         [0129]    In the present embodiment, as in the first embodiment, as shown in  FIG. 6 , the ultrasound probe system  1  may include a structure for fixing a position in the axial direction E of the main body portion  2  with respect to the sheath portion  5  using fitting of the stopper member  28  provided in the operation member  23  in the concave portions  21   p  and  21   q  provided in the operation member  21 . 
         [0130]    In the present embodiment, an ultrasound transmission medium is filled on the inside  2   i  of the main body portion  2 . Note that examples of the ultrasound transmission medium filled in the inside  2   i  include sterilized water, distilled water, and liquid paraffin. 
         [0131]    As shown in  FIG. 12  and  FIG. 13 , in the sheath portion  5 , a part facing the housing portion  8   y  is formed thinner in the radial direction than other parts. Therefore, a step portion  5   d  having a predetermined length from the distal end of the sheath portion  5  may be formed on the inner circumferential surface  5   n.    
         [0132]    If the step portion  5   d  is formed in a part of the inner circumferential surface  5   n  facing the housing portion  8   y , even if the space  8  between the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  of the sheath portion  5  is extremely narrow as shown in  FIG. 12  and  FIG. 13 , it is possible to secure a large housing space for a specimen using the step portion  5   d.    
         [0133]    The surface treatment for increasing hydrophobicity may be applied to a part of the outer circumferential surface  2   g  of the main body portion  2  opposed to the inner circumferential surface  5   n  formed by the step portion  5   d  of the sheath portion  5 . In other words, the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  may have a higher contact angle than the other parts on the outer circumferential surface  2   g  of the main body portion  2  not facing the housing portion  8   y  and the inner circumferential surface  5   n  formed by the step portion  5   d.    
         [0134]    More specifically, the hydrophobic coating may be applied to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y . The hydrophilic coating may be applied to the other parts on the outer circumferential surface  2   g  of the main body portion  2  not facing the housing portion  8   y  and the inner circumferential surface  5   n  formed by the step portion  5   d  of the sheath portion  5 . 
         [0135]    Naturally, it is also possible that coating is not performed and only the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  is formed of fluorine-based resin such as PTFE, PE, or the like, whereby the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  has higher hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  formed by the step portion  5   d  of the sheath portion  5 . 
         [0136]    When the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y  has higher hydrophobicity than the other parts on the outer circumferential surface  2   g  of the main body portion  2  and the inner circumferential surface  5   n  formed by the step portion  5   d  of the sheath portion  5  in this way, since the specimen contains fat as a main component, the specimen tends to adhere to a hydrophobic material. That is, the specimen tends to adhere to the part of the outer circumferential surface  2   g  of the main body portion  2  facing the housing portion  8   y.    
         [0137]    Note that the step portion  5   d  may be formed on the inner circumferential surface  5   n  of the sheath portion  5  of the ultrasound probe system  1  in the first embodiment. 
         [0138]    Note that a part opposed to the ultrasound observation portion  33  on the distal end side in the axial direction E of the sheath portion  5  has ultrasound permeability. 
         [0139]    Further, in the sheath portion  5 , a blade  30  may be provided along the axial direction E in a part through which ultrasound transmitted from the ultrasound observation portion  33  to the side surface direction S does not pass. Therefore, since stretchability in the axial direction E of the sheath portion  5  is deteriorated by the blade  30 , as shown in  FIG. 10  and  FIG. 12 , the specimen collection port  150  is prevented from suddenly opening when the specimen collection port  150  is inserted into the lesion part  85  in the pulmonary periphery bronchus  80  on the distal end side in the axial direction E of the ultrasound probe system  1  in the closed state. 
         [0140]    Note that the other components are the same as the components in the first embodiment. 
         [0141]    Next, action in the present embodiment is explained. 
         [0142]    First, an examiner takes out the sheath portion  5  and the main body portion  2  from a sterilized pack and fills the ultrasound transmission medium in the inside  2   i  of the main body portion  2 . 
         [0143]    Subsequently, the examiner inserts the ultrasound probe system  1  into the inside  2   i  of the main body portion  2  and rotates the sheath fixing ring  43  (see  FIG. 14 ) to thereby fix the proximal end in the axial direction E of the main body portion  2  as explained above. 
         [0144]    Thereafter, a step of filling saline in the space  8 , a step of inserting the distal end side in the axial direction E of the ultrasound probe system  1  to the pulmonary periphery bronchus  80 , a step of collecting a specimen of the lesion part  85  using the proximal end  3   k  and the distal end  5   s  to be housed in the housing portion  8   y , and a step of extracting the specimen housed in the housing portion  8   y  outside the subject after the collection are the same as the steps in the first embodiment explained above. Therefore, explanation of the steps is omitted. 
         [0145]    Note that, in the present embodiment, when the ultrasound probe system  1  is inserted in the pulmonary periphery bronchus  80  as shown in  FIG. 8 , as shown in  FIG. 14 , the proximal end in the axial direction E of the main body portion  2  is fixed using the sheath fixing pipe sleeve  41 , the rubber ring  42 , and the sheath fixing ring  43 . In addition, the main body portion  2  has higher stretchability in the axial direction E than the sheath portion  5 . Therefore, the stopper member  28  fits in the concave portion  21   p  as shown in  FIG. 6 . In a state in which the proximal end  3   k  of the distal end portion  3  is in contact with the distal end  5   s  of the sheath portion  5  with pressure backward in the axial direction E (the closed state of the specimen collection port shown in  FIG. 6  corresponding to  FIG. 4 ), as shown in  FIG. 12 , the distal end portion  3  is pressed forward in the axial direction E by the distal end  5   s  of the sheath portion  5 , whereby the main body portion  2  expands forward in the axial direction E. As a result, the ultrasound probe  31  is in a state in which the ultrasound probe  31  moves backward in the axial direction E on the inside  2   i  of the main body portion  2 . 
         [0146]    Finally, after extracting the specimen from the housing portion  8   y , the examiner discards the main body portion  2  and the sheath portion  5 . Thereafter, after cleaning the ultrasound probe  31  taken out from the inside  2   i  of the main body portion  2 , the examiner puts the ultrasound probe  31  in a sterilized pack and sterilizes and stores the ultrasound probe  31 . 
         [0147]    As explained above, in the present embodiment, the ultrasound probe  31  including the ultrasound observation portion  33  is provided to be movable back and forth in the axial direction E on the inside  2   i  of the main body portion  2 . That is, the ultrasound probe  31  including the ultrasound observation portion  33  is provided not to be fixed to the main body portion  2 . 
         [0148]    Therefore, after collection of the specimen, the main body portion  2  to which the distal end portion  3  provided with the proximal end  3   k  used for the specimen collection is fixed and the sheath portion  5  including the distal end  5   s  used for the specimen collection are discarded. However, the ultrasound probe  31  provided with the ultrasound observation portion  33  can be reused. Therefore, it is possible to perform specimen collection work at lower costs than in the first embodiment. 
         [0149]    Note that the other effects are the same as the effects in the first embodiment. 
         [0150]    A modification of the present embodiment is explained with reference to  FIG. 15 .  FIG. 15  is a partial sectional view of a distal end side in an axial direction of an ultrasound probe system showing a configuration of the modification in which the edge portion  7  is excluded from the housing portion  8   y  of the ultrasound probe system  1  shown in  FIG. 10 . 
         [0151]    As shown in  FIG. 15 , the edge portion  7  does not have to be provided in the housing portion  8   y . Therefore, it is difficult to extract the specimen housed in the housing portion  8   y . Otherwise, effects same as the effects in the second embodiment can be obtained. 
         [0152]    Another modification is explained below with reference to  FIG. 16  and  FIG. 17 .  FIG. 16  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration of a modification in which a plurality of grooves  5   e  along the axial direction are formed along a circumferential direction on the inner circumferential surface  5   n  of the sheath portion  5  of the ultrasound probe system  1  shown in  FIG. 10 .  FIG. 17  is a sectional view of the sheath portion taken along line XVII-XVII in  FIG. 16 . 
         [0153]    As shown in  FIGS. 16 and 17 , a plurality of grooves  5   e  along the axial direction E may be formed along the circumferential direction on the inner circumferential surface  5   n  of the sheath portion  5 . 
         [0154]    With such a configuration, the sheath portion  5  or the main body portion  2  can be smoothly moved back and forth in the axial direction E by the plurality of grooves  5   e . A space of the housing portion  8   y  can be secured larger by a size of the groove  5   e  than in the present embodiment shown in  FIG. 10 . Besides, eccentricity of the sheath portion  5  with respect to the main body portion  2  can be suppressed as much as possible by the plurality of grooves  5   e . Therefore, it is possible to surely collect a specimen. Note that the other effects are the same as the effects in the second embodiment. 
         [0155]    Another modification is explained below with reference to  FIG. 18  and  FIG. 19 .  FIG. 18  is a partial sectional view of the distal end side in the axial direction of the ultrasound probe system showing a configuration of a modification in which a plurality of grooves  2   e  along the axial direction are formed along the circumferential direction on the outer circumferential surface  2   g  of the main body portion  2  of the ultrasound probe system shown in  FIG. 10 .  FIG. 19  is a sectional view of the sheath portion and the main body portion taken along line XIX-XIX in  FIG. 18 . 
         [0156]    As shown in  FIG. 18  and  FIG. 19 , the plurality of groves  2   e  along the axial direction E may be formed along the circumferential direction on the outer circumferential surface  2   g  of the main body portion  2 . 
         [0157]    With such a configuration, the sheath portion  5  or the main body portion  2  can be smoothly moved back and forth in the axial direction E by the plurality of grooves  2   e . The space of the housing portion  8   y  can be secured larger by a size of the groove  2   e  than in the present embodiment shown in  FIG. 10 . Besides, eccentricity of the sheath portion  5  with respect to the main body portion  2  can be suppressed as much as possible by the plurality of grooves  2   e . Therefore, it is possible to surely collect a specimen. 
         [0158]    As shown in  FIG. 18 , the proximal end face  3   m  of the distal end portion  3  may be formed on a flat surface. That is, the proximal end  3   k  does not have to be formed at an acute angle. In this case, the proximal end  3   k  does not configure the specimen collecting portion. 
         [0159]    That is, in such a configuration, only the distal end  5   s  of the sheath portion  5  configures the specimen collecting portion. With such a configuration, effects same as the effects in the second embodiment can be obtained. 
         [0160]    The other effects are the same as the effects in the second embodiment. 
         [0161]    Naturally, the configurations shown in  FIG. 15  to  FIG. 19  can also be applied to the ultrasound probe system in the first embodiment. 
         [0162]    In the present embodiment, as shown in  FIG. 9  in the first embodiment, the distal end portion  3  may be provided separately from the main body portion  2 . 
         [0163]    Note that the ultrasound probe system  1  in the first and second embodiments explained above is used in, for example, an endoscope system shown in  FIG. 20 . 
         [0164]      FIG. 20  is a diagram schematically showing an endoscope system including the ultrasound probe system in the first and second embodiments. 
         [0165]    As shown in  FIG. 20 , the endoscope  122  included in an endoscope system  200  includes the long endoscope insertion portion  122   a  having flexibility. The operation portion  122   b  is provided on an examiner&#39;s side of the endoscope insertion portion  122   a.    
         [0166]    Further, a universal cord  122   c  is extended from the operation portion  122   b . A scope connector  122   d  is provided at an end portion of the universal cord  122   c . A video processor device and a light source device not shown in the figure are connected to the scope connector  122   d.    
         [0167]    The treatment instrument insertion port  122   e  is opened near a coupling portion of the endoscope insertion portion  122   a  and the operation portion  122   b . The treatment instrument insert-through channel communicates with the treatment instrument insertion port  122   e . The treatment instrument insert-through treatment instrument channel is formed in the endoscope insertion portion  122   a , and a distal end thereof is opened on a distal end face of the endoscope insertion portion  122   a.    
         [0168]    The connector  40  provided at the proximal end of the ultrasound probe system  1  is connected to a connector receiving portion  123   a  of the ultrasound observation device  123 . The ultrasound observation device  123  causes a monitor  124  to display an ultrasound image obtained by the ultrasound observation portion  13  ( 33 ). 
         [0169]    The present invention is not limited to the embodiments explained above and various alterations, modifications, and the like are possible in a range in which the gist of the present invention is not changed.