Abstract:
A compound of the formula (I) ##STR1## or a salt thereof, wherein R is hydrogen atom, phenyl group which may be substituted freely or a group of --(CH 2 ) n  --R 1  wherein n is an interger from 1 to 3 and R 1  is hydrogen atom, hydroxy group, lower alkoxy group, mercapto group, lower alkylthio group, amino group, di-lower alkylamino group, C 3-11  alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, 5- or 6-membered heterocyclic group, or phenyl group which may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy; R 2  and R 7  are different, hydrogen atom, C 1-11  alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, lower alkoxyalkyl group, lower alkylthioalkyl group, phenyl group whch may be substiuted freely, aralkyl group whose nucleus may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy or haloalkyl gorup or 5- or 6-membered heterocyclic group; R 3 , R 4  and R 5  are, the same or different, hydrogen atom, halogen atom, cyano group, nitro group, amino group, lower alkyl group, lower haloalkyl group, hydroxy group, lower alkoxygroup, aryloxy group, carboxy group or lower alkoxycarbonyl group; R 6  is hydrogen atom, halogen atom, lower alkyl group, phenyl group which may be substituted freely or aralkyl group which may be substituted freely; or R 6  and R 7  may be combined to form a group of --(CH 2 ) m  --(m is 3 or 4), which is useful e.g., a plant growth inhibitor.

Description:
BACKGROUND OF THE INVENTION 
     1. Field of the Invention 
     This invention relates to novel compounds which belong to 1,4-dihydro-4-oxo-3-pyridinecarboxamides. The compounds of this invention show growth inhibitory activities on plants and also antiinflammatory activity. 
     2. Description of the Prior Arts 
     Some compounds belonging to 1,4-dihydro-4-oxo-3-pyridinecarboxamides are found in literatures. 
     In Bull. Acad. Pol. Sci., Ser. Sci. Chim. 23(11), 901 (1975), Zankowska-Jasinska. W. et al., reported on N-(4-chlorophenyl)-1,4-dihydro-4-oxo-1,2,6-triphenyl-3-pyridinecarboxamide and 1-(4-chlorophenyl)-1,4-dihydro-4-oxo-N,2,6-triphenyl-3-pyridinecarboxamide. In Zesz. Nauk. Uniw. Jagiellon., Pr. Chim, 21., 141 (1976), Zankowska-Jasinska. W. et al., reported on 1,4-dihydro-4-oxo-N,2,6-triphenyl-3-pyridinecarboxamide, 1,4-dihydro-4-oxo-N,1,2,6-tetraphenyl-3-pyridinecarboxaminde, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide. 
     In Yakugakuzassi, 101, 40 (1981), Kato et al. reported on four compounds, namely N-(4-clorophenyl)-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N-phenyl-1-(phenylmethyl)-3-pyridinecarboxamide, 1,4-dihydro-N-(4-methoxyphenyl)-2,6-dimethyl-4-oxo-1-(phenylmethyl)-3-pyridinecarboxamide and N-(4-chlorophenyl)-1,4-dihydro-2,6-dimethyl-4-oxo-1-(phenylmethyl)-3-pyridinecarboxamide, as one of the studies on reactivity of ketene derivatives but they did not refer to utility thereof. Canadian Patent No. 1,115,278 [and also J. B. Pierce et al, J. Med. Chem. 25, 131 (1982)], there are disclosed 4-pyridone compounds possessing antiinflammatory activity, i.e., 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide, N,1-dibutyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, N,1-didodecyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, N-(4-chlorophenyl)-1-ethyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, etc. 
     Cephalosporins which contain a partial structure of 1,4-dihydro-4-oxo-3-pyridinecarboxamide are known as medicine in Japanese Patent Unexamined Publication Nos. Sho 54(1979)-24892, Sho 51(1976)-43783 and Sho 51(1976)-48686. 
     On the other hand, 1,4-dihydro-4-oxo-3-pyridine-carboxylic acid derivatives as compounds which show plant growth regulating activity, especially chemical hybridizing activity, are known in Japanese Patent Unexamined Publication Nos. Sho 52(1977)-144,676 (see also U.S. Pat. No. 4,051,142) and Sho 57(1982)-114,573 (see also E.P. 40,082). However, plant growth inhibitory agents whose active ingredients are 1,4-dihydro-4-oxo-3-pyridinecarboxamide as in the formula (I) shown below are not known. 
     SUMMARY OF THE INVENTION 
     This invention provides compounds of the formula (I) and salts thereof. ##STR2## or a salt thereof wherein R is hydrogen atom, phenyl group which may be substituted freely or a group of --(CH 2 ) n  --R 1  wherein n is an integer from 1 to 3 and R 1  is hydrogen atom, hydroxy group, lower alkoxy group, mercapto group, lower alkylthio group, amino group, di-lower alkylamino group, C 3-11  alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, 5- or 6-membered heterocyclic group, or phenyl group which may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy; R 2  and R 7  are different, hydrogen atom, C 1-11  alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, lower alkoxyalkyl group, lower alkylthioalkyl group, phenyl group which may be substituted freely, aralkyl group whose nucleus may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy or haloalkyl group or 5-or 6-membered heterocyclic group; 
     R 3 , R 4  and R 5  are, the same of different, hydrogen atom, halogen atom, cyano group, nitro group, amino group, lower alkyl group, lower haloalkyl group, hydroxy group, lower alkoxy group, aryloxy group, carboxy group or lower alkoxycarbonyl group; 
     R 6  is hydrogen atom, halogen atom, lower alkyl group, phenyl group which may be substituted freely or aralkyl group which may be substituted freely; or R 6  and R 7  may be combined to form a group of --(CH 2 ) m  --(m is 3 or 4). 
     This invention also provides plant growth inhibitors which contain at least one kind of compounds of the formula (I) and salts thereof as active ingredient. 
     DESCRIPTION OF PREFERRED EMBODIMENTS 
     The term of &#34;lower&#34; used for lower alkyl, lower alkoxy or like group in this invention means a group containing 1-5 carbon atoms. Specifically, there may be mentioned as lower alkyl group methyl, ethyl, propyl, isopropyl, butyl, isobutyl, pentyl or isopentyl; as lower alkoxy group methoxy, ethoxy, propoxy, isopropoxy or butoxy; as lower alkoxycarbonyl group methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl or butoxycarbonyl; or as lower alkylthio group methylthio, ethylthio, propylthio, isopropylthio, butylthio or pentylthio. As lower alkenyl or lower alkynyl group may be mentioned vinyl, allyl, isopropenyl 2-butenyl, 1,3-butadienyl, 2-pentenyl, 1,4-pentadienyl, 1,6-heptadienyl, 1-hexenyl, ethynyl or 2-propynyl. 
     Examples of cycloalkyl group include cyclopropyl, cyclopentyl and cyclohexyl. 
     Examples of haloalkyl group include trifluoromethyl, chloromethyl and the like. 
     Examples of lower alkoxyalkyl group include methoxymethyl, ethoxymethyl, propoxymethyl, butoxymethyl and the like. 
     Examples of lower alkylthioalkyl group include methylthiomethyl, ethylthiomethyl, methylthioethyl, ethylthioethyl and the like. 
     Halogen atom includes chlorine, bromine, fluorine and iodine atom. 
     Examples of aralkyl group include benzyl, 3-phenylpropyl, 4-phenylbutyl and the like. 
     Examples of aryloxy group include phenyloxy, naphtyloxy and the like. 
     5- or 6-Membered heterocyclic group includes 5- or 6-membered one containing one to three hetero atoms selected from nitrogen atom, oxygen atom and sulfur atom. The examples of the 5-membered heterocyclic group are furyl, tetrahydrofuryl, thienyl, thiazolyl, isothiazolyl, oxazolyl, isooxazolyl or pyrazolyl and the 6-membered heterocyclic group are pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl. These heterocyclic groups may be substituted by alkyl as methyl or ethyl, halogen atom or phenyl. When the heterocyclic group is substituted by phenyl, it may form a condensed ring combining the two adjacent carbon atoms in the heterocyclic group with phenyl group. Examples of the condensed ring are benzothiazolyl, benzofuryl, quinazolinyl or quinoxalinyl group. 
     Examples of substituent of phenyl group and aralkyl group which may be substituted freely include halogen atom, lower alkyl, lower alkoxy, trihaloalkyl, nitro, cyano and the like, and as numbers of the substituents one or two is preferable. 
     The compound of the formula (I) in this invention may form an addition salt with an acid such as hydrochloric acid, sulfuric acid, phosphoric acid, methanesulfonic acid, p-toluenesulfonic acid or trifluoroacetic acid when sufficiently basic, and also form a salt with an inorganic base when it contains a carboxylic group. Such salts are also included in this invention. 
    
    
     The compound of the formula (I) in this invention may be prepared by any of the following methods. 
     (Method A) ##STR3## [R, R 2 , R 3 , R 4  and R 5  of the formula (II) are the same as those in the formula (I)] 
     This method comprises reacting a 3-aminoacrylic acid anilide derivative (II) or its tautomer with 2,2,6-trimethyl-4H-1,3-dioxin-4-one in an appropriate solvent (e.g., toluene or xylene) under heating at a temperature of e.g., 100°-140° C. 2-Ethyl-2,6-dimethyl-4H-1,3-dioxin-4-one is also useful in place of 2,2,6-trimethyl-4H-1,3-dioxin-4-one. Also, in this method, 3-aminoacrylic acid anilide derivative (II) is not necessarily required to be in its isolated form but may be in the form of the crude reaction mixture of an amine of the formula (III) with a compound of the formula (IV) ##STR4## [R, R 2 , R 3 , R 4  and R 5  in the formula (III) and (IV) are the same as those in the formula (I).] 
     For the practical purpose it is convenient to use the crude reaction mixture as such 
     (Method B) ##STR5## [R, R 2 , R 3 , R 4 , R 5 , R 6  and R 7  in the formula (III) and (V) are the same as those in the formula (I).] 
     This method comprises reacting a 4-pyrone compound (V) corresponding to the formula (I), i.e., 4-oxo-N-phenyl-4H-pyran-3-carboxamide with ammonia or an amine of the formula (III) or a salt thereof in an appropriate solvent (e.g., ethanol or water) at a temperature from room temperature to about 60° C. The amount of ammonia or the amine employed is equimolecular or more to the 4-pyrone compound or a large excess if needed. When the amine is used as its available salt, it is required to convert to its free form by addition of an organic or an inorganic base in an amount needed for neutralization or more. 
     (Method C) ##STR6## [R, R 2 , R 3 , R 4 , R 5 , R 6  and R 7  in the formula (VI) and (VII) are the same meaning as defined in the formula (I).] 
     This method comprises reacting a carboxylic acid corresponding to the formula (I), i.e., 1,4-dihydro-4oxo-3-pyridinecarboxylic acid derivative (VI) with an aniline derivative (VII) in the presence of a condensing agent for dehydration. It is advantageous to use as the condensing agent for dehydration 1-substituted-2-halopyridinium salt and a tertiary amine according to the method described in e.g., Japanese Patent Unexamined Publication No. Sho 52(1977)-57,102. (Method C&#39;) ##STR7## [R, R 2 , R 3 , R 4 , R 5 , R 6  and R 7  in the formula (VIII) and (VII) are the same meaning as defined in the formula (I), and X is halogen atom.] 
     This method comprises reacting an acid halide (VIII) prepared easily by the reaction of (VI) and halogenating agent such as thionyl chloride with an aniline derivative (VII) in the presence of a base. 
     (Method D) ##STR8## [R, R 2 , R 3 , R 4 , R 5  and R 7  of the formula (IX) are the same as those in the formula (I).] 
     This method comprises reacting a 1,4-dihydro-4-oxo-3-pyridinecarboxamide derivative (IX) with a halogenating reagent. It is especially advantageous to use as the halogenating reagent, N-chlorosuccinimide or N-bromosuccinimide in an appropriate chlorinated hydrocarbon solvent (e.g., dichloromethane, chloroform, tetrachloromethane, trichloroethylene or tetrachloroethane) in the presence or absence of free-radical initiator. 
     The reaction may be also conducted by dissolving the compound (IX) in a halogenated hydrocarbon as mentioned above, and blowing or dropping into the resultant solution bromine or chlorine in gaseous or liquid state. 
     In the above halogenation of the compound (IX), it may additionally give the substitution at phenyl group which is bonded at the amide nitrogen atom. 
     (Method E) 
     This method in conducted by treating a compound of the formula (I) (R 6  is halogen atom) with an alkali metal halide which concerns an exchange of halogen atom (R 6 ) in the formula (I). It is useful to synthesize a compound of the formula (I) in which R 6  is fluorine atom and which it is difficult to produce by direct introduction. 
     (Method F) ##STR9## [R, R 2 , R 3 , R 4 , R 5 , R 6  and R 7  in the formula (II), (X), (XI) and (XII) are the same as those in the formula (I).] 
     This method comprises reacting an 3-aminoacrylic acid anilide derivative (II) with acid halide (X) in the presence of a base to yield a compound of the formula (XI), and then reacting this compound (XI) with a N,N-dimethylamide dimethylketal derivative (XII). It is possible to use an ester of formic acid instead of (XII) in the case that R 7  is hydrogen atom. This method is useful to synthesize a compound of the formula (I) in which R 6  is aryl group. 
     For herbicidal applications, the compounds of the present invention are generally formulated into herbicidal compositions. These compositions can be solids such as dusts, granules, or wettable powders; or they can be liquids such as solutions, aerosols, or emulsifiable concentrates. 
     For example, solid compositions such as dusts, wettable powders or granules can be prepared by blending the active compound with a solid inert carrier such as the kaolinites, bentonites, clays, talcs, silicas and the like. Liquids compositions such as solutions or emulsifiable concentrates can be prepared by dissolving the active compound with a liquid inert solvent such as xylene, ethanol, acetone, dimethylformamide, some vegetable oils, water and so on. 
     Surface active agents for wetting, dispersing or emulsifying are generally used with the herbicidal compositions as above defined. For example; polyoxyethylene-alkyl ethers, polyoxyethylene-sorbitan fatty acid esters, and other nonionic types; alkyl and alkylarlyl sulfonates and sulfates and their sodium salts and other anionic types or other types of surface active agents. 
     For pre-emergence applications these herbicidal compositions are usually applied either as sprays, dusts, or granules in the area in which suppression of vegetation is desied. For post-emergence applications control of established plant growth, sprays or dusts are most commonly used. These formulations may contain 10-80% for wettable powders, 1-10% for granules, or 10-50% for emulsifiable concentrates by weight of active ingredient. Dosage of these herbicidal compositions for pre-emergence or postemergence applications is generally 0.1-2 Kg by weight of active ingredient. 
     This invention is illustrated further by examples hereinafter. Also, growth-inhibitory activities on plants of the compounds of the invention are shown in reference examples. 
     Furthermore, related specific compounds in addition to the compounds shown in the examples are as follows; 
     1. 1-butyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     2. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide 
     3. 2-ethyl-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     4. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     5. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     6. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     7. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     8. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     9. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     10. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     11. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide 
     12. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     13. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     14. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     15. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     16. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     17. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     18. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     19. 1,2-dibutyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide 
     20. 2-butyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide 
     21. 2-butyl-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     22. 2-butyl-1-(4-chlorophenylmetyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     23. 2-butyl-cyclohexylmetyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     24. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     25. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     26. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     27. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     28. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-pentyl-3-pyridinecarboxamide, 
     29. 1-butyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl)-3-pyridinecarboxamide, 
     30. 1-hexyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl)-3-pyridinecarboxamide, 
     31. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     32. 1-(4-chlorophenylmethyl0-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     33. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     34. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     35. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     36. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     37. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     38. 1-butyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide 
     39. 1,4-dihydro-6-methyl-4-oxo-1,2-dipentyl-N-phenyl-3-pyridinecarboxamide, 
     40. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide 
     41. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     42. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     43. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     44. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     45. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     46. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     47. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     48. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N,2-diphenyl-3pyridinecarboxamide, 
     49. 1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     50. 1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     51. 1-butyl-2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     52. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide, 
     53. 2-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     54. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide, 
     55. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl3-pyridinecarboxamide, 
     56. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     57. 2-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     58. 2-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     59. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     60. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     61. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     62. 2-(3-chlorophenyl)-1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     64. 2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     65. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     66. 2-(3-chlorophenyl)-1-(4chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     67. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     68. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     69. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     70. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     71. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     72. 1-butyl-1,4-dihydro-6-methyl-2-(2-methyphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     73. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide, 
     74. 1-hexyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     75. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-furylmethyl-3-pyridinecarboxamide, 
     76. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     77. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     78. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     79. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     80. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     81. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     82. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     83. 1-butyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     84. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide, 
     85. 1-hexyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     86. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide, 
     87. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     88. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-3-pyridinecarboxamide, 
     89. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     90. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     91. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     92. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     93. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     95. 2-(2-furyl)-1,4-dihydro-6-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide, 
     96. 1-hexyl-2-(2furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     97. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     98. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     99. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     100. 2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     101. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     102. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     103. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     104. 1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     105. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     106. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     107. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     108. 1,4- dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     109. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     110. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     111. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     112. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     113. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     114. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     115. 1-butyl-1,4-dihydro-6-methyl4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     116. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     117. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridine-carboxamide, 
     118. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(phenylmethyl)-2-(3-pyridyl)-3-pyridinecarboxamide, 
     119. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     120. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     121. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     122. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     123. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     124. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     125. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     126. 1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     127. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     128. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     129. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     130. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     131. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     132. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3- pyridinecarboxamide,3-pyridinecarboxamide, 
     133. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     134. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     135. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     136. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     137. 1-butyl-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     138. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     139. 2-ethyl-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     140. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     141. 2-ethyl-1,4- dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     142. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     143. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     144. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     145. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     146. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     147. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     148. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     149. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-propyl-3-pyridinecarboxamide, 
     150. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     151. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     152. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     153. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     154. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     155. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     156. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     157. 1,2-dibutyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     158. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-propyl-3-pyridinecarboxamide, 
     159. 2-butyl-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     160. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     161. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     162. 2-butyl-1-(4-methylphenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     163. 2-butyl-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     164. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     165. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     166. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     167. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     168. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     169. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-1-pentyl-4-oxo-3-pyridinecarboxamide, 
     170. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     171. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     172. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     173. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     174. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     175. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     176. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     177. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     178. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     179. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     180. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1,2-dipentyl-3-pyridinecarboxamide, 
     181. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     182. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide, 
     183. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     184. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     185. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     186. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     187. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     188. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     189. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     190. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-phenyl-3-pyridinecarboxamide, 
     191. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     192. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     193. 1cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     194. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     195. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     196. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     197. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     198. 1-butyl-2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     199. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     200. 2-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     201. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     202. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     203. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     204. 2-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     205. 2-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     206. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     207. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     208. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     209. 1-butyl-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     210. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     211. 2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     212. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     213. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     214. 2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     215. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     216. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     217. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     218. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     219. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     220. 1-butyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     221. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     222. 1-hexyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     223. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     224. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     225. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     226. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     227. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     228. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     229. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     230. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     231. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     232. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     233. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     234. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     235. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     236. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     237. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     238. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     239. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     240. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     241. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     242. 1-butyl-2(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     243. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     244. 2-(2-furyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     245. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     246. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     247. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     248. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     249. 2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     250. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     251. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     252. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     253. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     254. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     255. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     256. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     257. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     258. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     259. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     260. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     261. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     262. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     263. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     264. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     265. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     266. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     267. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     268. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     269. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     270. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     271. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     272. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     273. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     274. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     275. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     276. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     277. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     278. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     279. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     280. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     281. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     282. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     283. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     284. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     285. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     286. 1-butyl-N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     287. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl4-oxo-1-pentyl-3-pyridinecarboxamide, 
     288. N-(2-chlorophenyl)-2-ethyl-1-hexyl-1,4-dihydro-6-methyl4-oxo-3-pyridinecarboxamide, 
     289. N-(2-chlorophenyl)-2-ehtyl-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     290. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     291. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     292. N-(2-chlorophenyl)-1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     293. N-(2-chlorophenyl)-2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     294. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     295. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     296. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     297. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     298. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-propyl-3-pyridinecarboxamide, 
     299. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     300. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide, 
     301. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     302. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     303. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     304. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     305. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     306. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     307. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     308. 1,2-dibuyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     309. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     310. 2-butyl-N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     311. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     312. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     313. 2-butyl-N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     314. 2-butyl-N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     315. 2-butyl-N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     316. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     317. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     318. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     319. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     320. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     321. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     322. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     323. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     324. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     325. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     326. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     327. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     328. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     329. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     330. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     331. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1,2-dipentyl-3-pyridinecarboxamide, 
     332. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     333. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide, 
     334. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     335. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     336. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     337. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     338. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     339. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     340. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     341. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-phenyl-3-pyridinecarboxamide, 
     342. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     343. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-phenylmethyl3-pyridinecarboxamide, 
     344. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     345. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     346. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     347. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     348. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     349. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     350. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     351. 1-butyl-N,2-bis(2-chlorophenyl)1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     352. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     353. N,2-bis(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     354. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     355. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     356. N,2-bis(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     357. N,2-bis(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     358. N,2-bis(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     359. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     360. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     361. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     362. 1-butyl-N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     363. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     364. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     365. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     366. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     367. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     368. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     369. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     370. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     371. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     372. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     373. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     374. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     375. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     376. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     377. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     378. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     379. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     380. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     381. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     382. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     383. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     384. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     385. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     386. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     387. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     388. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     389. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     390. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     391. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     392. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     393. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     394. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     395. 1-butyl-N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     396. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 397. N-(2-chlorophenyl)-2-(2-furyl)-1-hexyl-1,4-dihydro-6-methyl-4oxo--3-pyridinecarboxamide, 
     398. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     399. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     400. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     401. N-(2-chlorophenyl)-1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     402. N-(2-chlorophenyl)-2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     403. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     404. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     405. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     406. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     407. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4oxo-1-pentyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     408. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     409. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     410. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     411. N-(2-chlorophenyl)-1-(4chlorophenylmethyl)-1,4-dihydro-6methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     412. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     413. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     414. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     415. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     416. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     417. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     418. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     419. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     420. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     421. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     422. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     423. N-(2-chlorophenyl)-1-cyclohexymethyl-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     424. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     425. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     426. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     427. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     428. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     429. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     430. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     431. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     432. N-(2-chlorophenyl)-1.4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     433. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     434. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     435. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     436. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     437. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     438. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     439. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     440. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-methylphenylmethyl)-3-pyridinecarboxamide, 
     441. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     442. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl-4-oxo-3-pyridinecarboxamide, 
     443. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     444. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     445. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     446. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     447. 1,4-dihydro-6methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide, 
     448. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     449. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     450. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     451. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     452. 1,4-dihydro-6-methyl-N-(2,3-dimethylpheny;)-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     453. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     454. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     455. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     456. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     457. 2-butyl-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     458. 2-butyl-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     459. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     460. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     461. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     462. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     463. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     464. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     465. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     466. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     467. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide, 
     468. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     469. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     470. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     471. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide, 
     472. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     473. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     474. 1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     475. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     476. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     477. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     478. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     479. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     480. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     481. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     482. 1-(2-furylmethyl)1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     483. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     484. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     485. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     486. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     487. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     488. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     489. 2-(2-chlorophenyl)-1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     490. 2(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     491. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     492. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     493. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     494. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     495. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     496. 2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     497. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     498. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     499. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     500. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     501. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     502. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     503. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     504. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     505. 1cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     506. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     507. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     508. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     509. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-pyridelmethyl)-3-pyridinecarboxamide, 
     510. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     511. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-1(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     512. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     513. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2(3-methylphenyl)-N-(2,3-dimethylmethyl)-4-oxo-3-pyridinecarboxamide, 
     514. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     515 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethyplhenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     516. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     517. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     518. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     519. 2-(2furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     520. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     521. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     522. 2-(2-furyl)-1-(2furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     523. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     524. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     525. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     526. 1,4-dihydro-6-methyl-N-(s,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide, 
     527. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     528. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     529. 1-cylcohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)--4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     530. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     531. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     532. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     533. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2ppyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     534. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     535. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)1-(4methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     536. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3ppyridyl)-3-pyridinecarboxamide, 
     537. 1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     538. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     539. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     540. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide, 
     541. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridylmethyl)-3-pyridinecarboxamide, 
     542. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     543. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     544. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     545. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     546. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3dimethylphenyl)-4-oxo-2-(4-puridyl)-3-pyridinecarboxamide, 
     547. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide, 
     548. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1(3-pyridylmethyl)-3-pyridinecarboxamide, 
     549. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1(4-pyridylmethyl)-3-pyridinecarboxamide, 
     550. 1-butyl-2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     551. 2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     552. 2-ethyl-1-hexyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)4-oxo-3-pyridinecarboxamide, 
     553. 2-ethyl-1,4dihydro-1(3-methoxypropyl)-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     554. 2-ethyl-1,4dihydro-1-(2-methoxyethyl)-6-methyl-N-(2,6dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     555. 1-(ethoxyethyl)-2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     556. 1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1,2-diphenyl-3-pyridinecarboxamide, 
     557. 1-(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     558. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     559. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     660. 1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     561. 1,4dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     562. 1,4dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     563. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6 -dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     564. 1,2-bis(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     565. 2-(2-chlorophenyl)-1(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     566. 2-(2-chlorophenyl)-1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     567. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     568. 1-(2-chlorophenyl)-2(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     569. 2-(2-chlorophenyl)-1(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     570. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     571. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     572. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     573. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     574. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     575. 2-(3-chlorophenyl)-8-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     576. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     577. 1,4dihydro-6-methyl-2(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     578. 1-(2-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     579. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     580. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-6-oxo-3-pyridinecarboxamide, 
     581. 1,4dihydro-6-methyl-1,2-bis(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     582. 1,4dihydro-6-methyl-2-(2-methylphenyl)-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     583. 1,4dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     584. 1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     585. 1-(1-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     586. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     587. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     588. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4oxo-3-pyridinecarboxamide, 
     589. 1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     590. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-1(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     591. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     592. 1-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     593. 1-(3-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     594. 1-(4-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)4-oxo-3-pyridinecarboxamide, 
     595. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     596. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     597. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     598. 1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-(2-pyridyl)-3-pyridinecarboxamide, 
     599. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     600. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     601. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     602. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     603. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-pyridyl)-3-pyridinecarboxamide, 
     604. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     605. 1,4-dihydro-6-methyl-N-(2,6-dimethyphenyl)-4-oxo-1-phenyl-2(3-pyridyl)-3-pyridinecarboxamide, 
     606. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     607. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide, 
     608. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     609.1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     610. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     611. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     612. 1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-2(4-pyridyl)-3-pyridinecarboxamide, 
     613. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pryridyl)-3-pyridinecarboxamide, 
     614. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     615. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     616. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     617. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     618. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     619. 5-bromo-1-butyl-2-ethyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-44-oxo-3-pyridinecarboxamide, 
     620. 5-bromo-2-ethyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     621. 5-bromo-2-ethyl-1-hexyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     622. 5-bromo-2-ethyl-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-N-(2,6-dimethylphenyl)-4oxo-3-pyridinecarboxamide, 
     623. 5-bromo-2-ethyl-1,4-dihydro-1(2-methoxyethyl)-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     624. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     625. 2-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     626. 5-bromo-2-ethyl-N-(2,6-diethylmethyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     627. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     628. 2ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     629. 1-(2-ethoxyethyl)-2ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     630. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     631. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     632. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     6.33 N-(2,6diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2phenyl-3-pyridinecarboxamide, 
     634. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(4-methylphenyl)-4-2phenyl-3-pyridinecarboxamide, 
     635. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     636. 1,2-bis(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     637. 2-(2-chlorophenyl)-1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     638. 2-(2-chlorophenyl)-1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     639. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     640. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     641. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     642. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     643. 1-(2-chlorophenyl)-2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     644. 1,2-bis(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     645. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     646. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     647. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     648. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     649. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     650. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     651. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     652. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     653. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     654. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     655. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     656. N-(2,6-diethylphenyl)-1,4-dihydro-6methyl-2-(3-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     657. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     658. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     659. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     660. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     661. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     662. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(4-methylphenyl)-4-oxo- 3-pyridinecarboxamide, 
     663. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     664. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     665. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4oxo-3-pyridinecarboxamide, 
     666. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-8,6-methyl-4-oxo-3-pyridinecarboxamide, 
     667. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     668. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     669. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     670. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2(2-pyridyl)-3-pyridinecarboxamide, 
     671. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     672. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     673. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     674. N-(2,6-diethelphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     675. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(3-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     676. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2(2pyridyl)-3-pyridinecarboxamide, 
     677. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     678. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     679. 1(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     680. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     681. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide, 
     682. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide, 
     683. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     684. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     685. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     686. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     687. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     688. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     689. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     690. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     691. 5-bromo-1-(2-ethoxyethyl)-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     692. 5-bromo-2-ethyl-N-(2,6-diethelphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     693. 5-bromo-2-ethyl-N-(2,6-diethylphenyl)-1-hesyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     694. 5-bromo-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     695. 1-butyl-2-ethyl-Np(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     696. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     697. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     698. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     699. 2-ethyl-N-(2-ethyl-6methylphenyl)-1,4-dihydro-1(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     700. 1-(2-ethoxyethyl)-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     701. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide, 
     702. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     703. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     705. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     706. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     707. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     708. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     709. 1,2-bis(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     710. 2-(2-chlorophenyl)-1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     711. 2-(2-chlorophenyl)-1(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     712. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     713. 2(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     714. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     715. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     716. 1-(2-chlorophenyl)-2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     717. 1,2-bis(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     718. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-N-(2ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     719. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     720. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-=b 6-methyl-1(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     721. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     722. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     723. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl-4-oxo-3-pyridinecarboxamide, 
     724. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     725. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     726. N-(2-ethyl-6-methylphenyl)-8,6-methyl-1,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     727. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(3-methylphenyl)4-oxo-3-pyridinecarboxamide, 
     728. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     729. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6methyl-2(3-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     730. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     731. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     732. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     733. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     734. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     735. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     736. N-(2-ethyl-6methylphenyl)-2(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide, 
     737. 1(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-0x0-3-pyridinecarboxamide, 
     738. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     739. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     740. N-(2-ethyl-6methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl)-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     741. N-(2-ethyl-6-methylphenyl)-2(2-furyl)-1,4-dihydro-6-methyl)-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     742. N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     743. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridyl)-3-pyridinecarboxamide, 
     744. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     745. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     746. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     747. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2(2-pyridyl)-3-pyridinecarboxamide, 
     748. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(3-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     749. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     750. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide, 
     751. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     752. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     753. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pridyl)-3-pyridinecarboxamide, 
     754. N-(2-ethyl-6-methelphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide, 
     755. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     756. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(4-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide, 
     757. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide, 
     758. 1(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     759. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     760. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     761. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     762. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     763. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6methyl-1-(4-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide, 
     764. 5-bromo-1-butyl-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     765. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     766. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     767. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide, 
     768. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4oxo-3-pyridinecarboxamide, 
     769. 6-ethyl-1,4-dihydro-2-methyl-1(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     770. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-4oxo-N-phenyl-3-pyridinecarboxamide, 
     771. 1-cyclohexylmethyl-6-methyl-1,4-dihydro-2-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     772. 6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     773. 6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     774. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     775. 1-cyclohexylmethyl-6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     776. N-(2-chlorophenyl)-6ethyl-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     777. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-2-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     778. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     779. N-(2-chlorophenyl)-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     780. 6-ethyl-1,4-dihydro-4-oxo-N-phenyl-1-phenylmethyl-2-propyl-3-pyridinecarboxamide, 
     781. 6-ethyl-1,4-dihydro-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     782. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     783. 1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     784. 6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide, 
     785. 6-ethyl-1,4-dihydro-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     786. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     787. 1cyclohexylmethyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     788. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide, 
     789. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     790. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-2-propyl-3-pyridinecarboxamide, 
     791. N-(2-chlorophenyl)-1-clorohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-2-propyl-3-pyridinecarboxamide, 
     792. 2-butyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide, 
     793. 2-butyl-6-ethyl-1,4-dihydro-1(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     794. 2-butyl-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-N--phenyl-3-pyridinecarboxamide, 
     795. 2-butyl-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     796. 2-butyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     797/ 2-butyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     798. 2-butyl-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     799. 2-butyl-1-cyclohexylmethyl-6ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     800. 2-butyl-N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     801. 2-butyl-N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-1(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide, 
     802. 2-butyl-N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide, 
     803. 2-butyl-N-(2-chlorophenyl)-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide, 
     804. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     805. 6-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     806. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     807. 5-bromo-6-ethyl-N-(2,6diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     808. 5-bromo-6ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     809. 5-bromo-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     810. 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     811. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     812. 6-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     813. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     814. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-(2-phenylmethyl)-3-pyridinecarboxamide, 
     815. 1-butyl-5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     816. 5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     817. 5,6-diethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     818. 5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     819. 5,6-diethyl-N-(2,6 -diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-(1-phenylmethyl)-3-pyridinecarboxamide, 
     820. 1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     821. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     822. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     823. 6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     824. 6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide, 
     825. 5-bromo-1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     826. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     827. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     838. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     829. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide, 
     830. 1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     831. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     832. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     833. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     834. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     835. 1-butyl-5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     836. 5,6-diethyl-N-(2-ethyl-6methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     837. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     838. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     839. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide, 
     840. 1-butyl-6-ethyl-N-(2,6-dimethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 
     841. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     842. 6-ethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     843. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     844. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide, 
     845. 5-bromo-1-butyl-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     846. 5-bromo-6-ethyl-1,4-dihydro-2methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     847. 5-bromo-6-ethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     848. 5-bromo-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethelphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     849. 5-bromo-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide, 
     850. 1-butyl-6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     851. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     852. 6-ethyl-1-hexyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     853. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     854. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide, 
     855. 1-butyl-5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     856. 5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     857. 5,6-diethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide, 
     858. 5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide, 
     859. 5,6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     860. 5-ethyl-N-(2,6-diethylphenyl)-8,1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     861. N-(4-bromo-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     862. 2-butyl-5-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     863. 5-bromo-1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     864. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     865. 5-bromo-2-butyl-N-(2,6-diethylphenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     866. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-2-butyl-1-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     867. 1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     868. N-(4-bromo-2,6-diethylphenyl)-1-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     869. 2-butyl-1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     870. N-(4-bromo-2,6-diethylphenyl)-2-butyl-1-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     871. 5-bromo-N-(2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     872. 5-bromo-2-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-methyl-4-oxo-3-pyridinecarboxamide, 
     873. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1,2-dimethyl-4-oxo-3-pyridinecarboxamide, 
     874. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,5-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     875. N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1,5-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     876. 2-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     877. N-(4-bromo-2,6-diethylphenyl)-2-butyl-6-ethyl-1,4-dihydro-1,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     878. 5-chloro-N-(2,6diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     879. N-(4-bromo-2,6-diethylphenyl)5-chloro-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     880. 2-butyl-5-chloro-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     881. N-(4-bromo-2,6-diethylphenyl)-2-butyl-5-chloro-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     882. 5-bromo-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     883. N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     884. 5-bromo-2-butyl-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     885. 2-butyl-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     886. 5-bromo-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     887. N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     888. 5-bromo-2-butyl-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     889. 2-butyl-N-(2,6-diethyl-4-methylphenyl)1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     890. N-(4-bromo-2,6-diethylphenyl)-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide, 
     891. N-(4-bromo-2,6-diethylphenyl)-6-methyl-1,4-dihydro-2,5-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide, 
     892. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide, 
     893. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide, 
     894. N-(4-bromo-2,6-diethylphenyl)-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     895. N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     896. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     897. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 
     898. N-(4-bromo-2,6-diethylphenyl)-1-butyl-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     899. N-(4-bromo-2,6-diethylphenyl)-1-butyl-6-ethyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     900. 1-butyl-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     901. 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide, 
     902. 1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     903. 1-(3-bromophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     904. 2-ethyl-1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     905. 2-ethyl-1,4-dihydro-1-(3-iodophenyl)-6-methyl-4oxo-N-phenyl-3-pyridinecarboxamide, 
     906. 2-ethyl-1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl4-oxo-N-phenyl-3-pyridinecarboxamide, 
     907. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     908. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     909. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     910. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     911. 1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide, 
     912. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl3-pyridinecarboxamide, 
     913. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     914. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     915. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     916. 1(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide, 
     917. 2-butyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     918. 2-butyl-1(2,5-dichlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     919. 2-butyl-1(2,6-dichlorophenyl)1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide, 
     920. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide, 
     921. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide, 
     922. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide, 
     923. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide, 
     924. 1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide, 
     925. 1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     926. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide, 
     927. 2-butyl-1-(3-chloropheynl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide, 
     928. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo2-pentyl-3-pyridinecarboxamide, 
     929. 1(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     930. N-(2-chlorophenyl)-1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     931. N-(2-chlorophenyl)-1(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     932. 2-butyl-N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide, 
     933. N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide, 
     934. N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide, 
     935. 5-bromo-N-(2,6-diethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     936. 5-bromo-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     937. 5-bromo-N-(2,6-diethyl-4methylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     938. 5-bromo-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     939. 5-bromo-2-butyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     940. 5-bromo-N-(2,4,,6-triethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     941. 5-bromo-N-(2,4,6-triethylphenyl)-1,4-dihydro-1.6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     942. 5-bromo-N-(2,6-diethyl-4-propylphenyl)1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     943. 5bromo-2-butyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     944. 5-bromo-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     945. 5-bromo-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     946. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     947. 5-bromo-2-butyl-N-(2,6-diethyl-4(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     948. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-2-methoxymethyl-1,4-dimethyl-4-oxo-3-pyridinecarboxamide, 
     949. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     950. 5-bromo-N-(2,6diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     951. 5-bromo-2-butyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     952. 5bromo-N-(b 2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-2-methoxymethyl-1,6dimethyl-4-oxo-3-pyridinecarboxamide, 
     953. 5-bromo-N-(2,6-diethyl-4(1,1dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-2methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     954. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     955. 5-bromo-2-butyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     956. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     957. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     958. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     959. 5-bromo-N-(bromo-2,6-diethylphenyl)-2-butyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     960. 5-bromo-2-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     961. 5-bromo-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     962. 5-bromo-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     963. 5-bromo-2-butyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     964. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     965. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl)-4-oxo-3-pyridinecarboxamide, 
     966. 5-bromo-2-butyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     967. 5-bromo-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     968. 5-bromo-N-(b 2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     969. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     970. 5-bromo-2-butyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     971. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-2-methoxyphenyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     972. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     973. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     974. N-(4-amino-2,6-diethylphenyl)-5-bromo-2-butyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     975. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo3-pyridinecarboxamide, 
     976. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     977. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     978. 5-bromo-2-butyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     979. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     980. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4oxo-3-pyridinecarboxamide, 
     981. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     982. 5-bromo-2-butyl-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     983. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     984. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     985. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4oxo-2-propyl-3-pyridinecarboxamide, 
     986. 5-bromo-2-butyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     987. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     988. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     989. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     990. 5-bromo-2-butyl-N-(2,6-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     991. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro--2methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     992. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide, 
     993. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)1,4-dihydro-1,6-dimethyl-4oxo-2-propyl-3-pyridinecarboxamide, 
     994. 2-butyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,5,6trimethyl-4-oxo-3-pyridinecarboxamide, 
     995. N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     996. 2-butyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     997. N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     998. 2-butyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     999. N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1000. 2-butyl-N-(2,6-diethyl-4(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1001. N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1002. 2-butyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1003. 2-butyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1004. N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1005. 2-butyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1006. N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,5,6trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1007. 2-butyl-N-(2,6-dimethyl-4-methoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1008.N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1009. 2-butyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1010. N-(4-amino-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1011. N-(4-amino-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1012. N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1013. 2-butyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1014. N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-[1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1015. 2-butyl-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1016. N-(2,6-diethyl-4-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1017. 2-butyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1018. N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1019. 2-butyl-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide, 
     1020. 5-ethyl-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1021. 2-butyl-5-ethyl-N-(2,6-diethyl-6-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1022. 5-ethyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1023. 2-butyl-5-ethyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl--oxo-3-pyridinecarboxamide, 
     1024. 5-ethyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1025. 2-butyl-5-ethyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1026. 5-ethyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1027. 2-butyl-5-ethyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1028. 5-ethyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1029. 2-butyl-5-ethyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1030. 5-ethyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1031. 2-butyl-5-ethyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1032. 5-ethyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1033. 2-butyl-5-ethyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro--1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1034. 5-ethyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1035. 2-butyl-5-ethyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1036. 5-ethyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1037. 2-butyl-5-ethyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1038. 5-ethyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1039. 2-butyl-5-ethyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1040. N-(4-amino-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1041. N-(4-amino-2,6-diethylphenyl)-2-butyl-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1042. 5-ethyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1043. 2-butyl-5-ethyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1044. N-(4-amino-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1045. 2-butyl-N-(4-cyano-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     1046. 5-ethyl-n-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1047. 2-butyl-5-ethyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6dimethyl-4-oxo-3-pyridinecarboxamide, 
     1048. 5-ethyl-N-(2,6-diethyl-4ethoxycarbonylphenyl)-1,4-dihydro-1,6dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide, 
     1049. 2-butyl-5-ethyl-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide, 
     EXAMPLE 1 
     1-butyl-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide 
     A mixture of 4.42 g (18.47 mmol) of α-benzoylacetanilide, 1.89 g (25.84 mmol) of n-butylamine, one drop of acetic acid and 25 ml of toluene was refluxed for 1.5 hours, while the resulted water and excess of butylamine were removed through a Dean-Stark&#39;s water separator, together with about 12 ml of toluene. While heating, to the mixture was dropwise added a solution of 7.2 g (46.18 mmol) of 2-ethyl-2,6-dimethyl-4H-1,3-dioxin-4-one in 16 ml of toluene within about 30 minutes and after the resulted mixture was refluxed for forty minutes, it was cooled to room temperature. The crystals precipitated was separated by filtration and dried under vacuo to afford 3.72 g of the title compound having mp. 189.5°-193° C. 
     EXAMPLE 2 
     1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-pentyl-3-pyridinecarboxamide 
     1 g (3.23 mmol) of 6-methyl-4-oxo-N,2-diphenyl-4-H-pyran-3-carboxamide and 590 mg (6.78 mmol) of benzylamine were dissolved in 10 ml of ethanol, and the resulted mixture was stirred over night at room temperature. Ethanol was removed under vacuo. The crystal residue was recrystallized from ethylacetate to afford 700 mg of the title compound having mp. 164°-165.5° C. 
     EXAMPLE 3 
     5-bromo-1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide 
     To a mixture of 700 mg (1.90 mmol) of 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 14 ml of methylene chloride and 1.2 g (7.40 mmol) of sodium carbonate was added a solution of 303 mg (1.90 mmol) of bromine in 5 ml of methylene chloride under vigorous stirring. After the completion of addition the mixture was stirred for 6 hours. The insoluble product in methylene chloride was filtered off and the filtrate was concentrated in vacuo to give a crystalline residue. The residue was recrystallized from benzene and cyclohexane to afford 615 mg of the title compound having mp. 132.5°-133.5° C. 
     EXAMPLE 4 
     1,4-dihydro-2-methyl-4-oxo-N,5-diphenyl-1-phenylmethyl -3-pyridinecarboxamide 
     To a mixture of 2.66 g (10 mmol) of 3-benzylaminocrotonanilide, 0.87 g (11 mmol) of pyridine and 30 ml of methylene chloride was added a mixture of 1.45 ml (11 mmol) of phenylacetylchloride and 5 ml of methylene chloride under ice cooling. After the mixture was stirred for 2.5 hours under ice cooling, it was poured into ice water and extracted. The organic layer was dried and concentrated in an usual manner and the residue was crystallized form benzene and diethylether to afford 1.81 g of 2-phenylacetyl-3-phenylmethylamino-2-butenoylanilide. A mixture of 1.60 g (4.16 mmol) of 2-phenylacetyl-3-phenylmethylamino-2-butenoylanilide, 2.23 g of N,N-dimethylformamide dimethylacetal, 0.2 ml of triethylamine and 5 ml of benzene was refluxed for 80 minutes under nitrogen atmosphere. The reaction mixture was concentrated under vacuo to give an oily residue, which was purified by column chromatography and crystallization from ethylacetate to afford 0.70 g of the title compound. 
     The following Table 1 and Table 2 show physical properties of the compounds associated with this invention. Numbers in the column &#34;Evaluation&#34; in Table 2 were obtained as follows: 
     A carrier was prepared by mixing 50 parts (by weight) of talc, 25 parts of bentonite, 2 parts of Solpole-9047 (Toho Chemical Co., Ltd, Japan) and 3 parts of Solpole-5039 (Toho Chemical Co., Ltd, Japan). 50 parts of a test compound and 200 parts of the carrier were mixed to obtain 20% wettable powder, followed by dispersing the powder in distilled water to make a dispersion of the definite concentrations. 
     Seeds of Oryza sativa L., Echinochloa crus-galli L., and Raphanus sativus L. were germinated in a laboratory dish, to which the dispersion was added. After breeding for 7 days in a thermostatic box kept at 25° C. under illumination of fluorescent tubes, growth of plant was observed. In the column of &#34;Evaluation&#34; of Table 2, the designation 1 denotes no influence, 2 denotes 25% growth inhibition, 3 denotes 50% growth inhibition, 4 denotes 75% growth inhibition and 5 denotes 100% growth inhibition. 
     
                                           TABLE 1__________________________________________________________________________Example                                    Melting                                            MolecularNO.   R       R.sub.2                R.sub.3                     R.sub.4                         R.sub.5                             R.sub.6                                  R.sub.7                                      point (°C.)                                            formula Method__________________________________________________________________________1     phenylmethyl         C.sub.2 H.sub.5                H    H   H   H    CH.sub.3                                      155-157                                            C.sub.22 H.sub.22                                            N.sub.2 O.sub.2                                                    A2     4-methyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   153-154                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    A phenylmethyl3     butyl   n-C.sub.3 H.sub.7                &#34;    &#34;   &#34;   &#34;    &#34;   116-117                                            C.sub.20 H.sub.26                                            N.sub.2 O.sub.2                                                    A4     phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   150-152                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    A5     2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   132-133                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A6     phenylmethyl         n-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;   132-134                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A7     4-methyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A phenylmethyl8     phenylmethyl         iso-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;   112.5-114                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A9     &#34;       n-C.sub.5 H.sub.11                &#34;    &#34;   &#34;   &#34;    &#34;   114-115.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A10    &#34;       n-C.sub.7 H.sub.15                &#34;    &#34;   &#34;   &#34;    &#34;   86-88 C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    A11    &#34;       n-C.sub.9 H.sub.19                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.29 H.sub.36                                            N.sub.2 O.sub.2                                                    A12    &#34;       phenylmethyl                &#34;    &#34;   &#34;   &#34;    &#34;   190.5-193                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A13    4-methyl         phenylmethyl                H    H   H   H    CH.sub.3                                      188-189                                            C.sub.28 H.sub.26                                            N.sub.2 O.sub.2                                                    A phenylmethyl14    H       phenyl &#34;    &#34;   &#34;   &#34;    &#34;   277-279                                            C.sub.19 H.sub.16                                            N.sub.2 O.sub.2                                                    B15    methyl  &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   215-217                                            C.sub.20 H.sub.18                                            N.sub.2 O.sub.2                                                    B16    ethyl   &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   207-209                                            C.sub.21 H.sub.20                                            N.sub.2 O.sub.2                                                    B17    propyl  &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   180-183                                            C.sub.22 H.sub.22                                            N.sub.2 O.sub.2                                                    B18    butyl   &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   189.5-193                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    A19    pentyl  &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   170.5-173                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.                                                    B20    hexyl   &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   137-138.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A21    octyl   &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    A22    3-      &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   203-204.5                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.3                                                    A methoxypropyl23    2-      &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   191-192                                            C.sub.22 H.sub.22                                            N.sub.2 O.sub.3                                                    A methoxyethyl24    phenyl  &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   more than                                            C.sub.25 H.sub.20                                            N.sub.2 O.sub.2                                                    A                                      300° C.25    phenylmethyl         phenyl H    H   H   H    CH.sub.3                                      185.5-187.5                                            C.sub.26 H.sub.22                                            N.sub.2 O.sub.2                                                    A26    4-methyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   191.5-193                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A phenylmethyl27    4-chloro         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   198-200                                            C.sub.26 H.sub.21                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl28    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   168-171                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A29    2-furylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.20                                            N.sub.2 O.sub.                                                    A30    2-      &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   209-211                                            C.sub.25 H.sub.21                                            N.sub.3 O.sub.2                                                    A pyridylmethyl31    phenylmethyl         3-chloro                &#34;    &#34;   &#34;   &#34;    &#34;   227-229                                            C.sub.26 H.sub.21                                            ClN.sub.2 O.sub.2                                                    A         phenyl32    &#34;       4-chloro                &#34;    &#34;   &#34;   &#34;    &#34;   222.5-228                                            C.sub.26 H.sub.21                                            ClN.sub.2 O.sub.2                                                    A         phenyl33    &#34;       4-methyl                &#34;    &#34;   &#34;   &#34;    &#34;   172-175                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A         phenyl34    &#34;       2-furyl                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.20                                            N.sub.2 O.sub.3                                                    A35    &#34;       n-C.sub.3 H.sub.7                2-CH.sub.3                     &#34;   &#34;   &#34;    &#34;   139-140.5                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A36    4-chloro         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   124-125                                            C.sub.24 H.sub.25                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl37    2-phenylethyl         n-C.sub.3 H.sub.7                2-CH.sub.3                     H   H   H    CH.sub.3                                      132.5-134.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A38    butyl   phenyl &#34;    &#34;   &#34;   &#34;    &#34;   166.5-168.0                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A39    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   231-233                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A40    4-chloro         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   106-109                                            C.sub.27 H.sub.23                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl41    butyl   &#34;      2-Cl &#34;   &#34;   &#34;    &#34;   174-175                                            C.sub.23 H.sub.23                                            ClN.sub.2 O.sub.2                                                    A42    &#34;       &#34;      2-CH.sub.3                     3-CH.sub.3                         &#34;   &#34;    &#34;   221-224                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A43    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   214-216                                            C.sub.28 H.sub.26                                            N.sub.2 O.sub.2                                                    A44    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   215-217.5                                            C.sub.29 H.sub.28                                            N.sub.2 O.sub.2                                                    A45    butyl   &#34;      2-CH.sub.3                     6-CH.sub.3                         &#34;   &#34;    &#34;   166-168.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A46    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.28 H.sub.26                                            N.sub.2 O.sub.2                                                    A47    butyl   H      2-C.sub. 2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    &#34;   151-152.5                                            C.sub.21 H.sub.28                                            N.sub.2 O.sub.2                                                     C&#39;48    &#34;       C.sub.2 H.sub.5                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.23 H.sub.32                                            N.sub.2 O.sub.2                                                    A49    phenylmethyl         C.sub.2 H.sub.5                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         H   H    CH.sub.3  C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    A50    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    A51    propyl  n-C.sub.3 H.sub.7                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.23 H.sub.32                                            N.sub.2 O.sub.2                                                    A52    butyl   &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.34                                            N.sub.2 O.sub.2                                                    A53    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   152-154                                            C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    A54    butyl   n-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.25 H.sub.36                                            N.sub.2 O.sub.2                                                    A55    &#34;       iso-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.25 H.sub.36                                            N.sub.2 O.sub.2                                                    A56    &#34;       phenylmethyl                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.28 H.sub.34                                            N.sub.2 O.sub.2                                                    A57    &#34;       phenyl &#34;    &#34;   &#34;   &#34;    &#34;   152-153                                            C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    A58    phenyl  &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   more than                                            C.sub.29 H.sub.28                                            N.sub.2 O.sub.2                                                    A                                      300° C.59    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   100-103                                            C.sub.30 H.sub.30                                            N.sub.2 O.sub.2                                                    A60    2-phenylmethyl         phenyl &#34;    &#34;   &#34;   &#34;    &#34;   196-197.5                                            C.sub.31 H.sub.32                                            N.sub.2 O.sub.2                                                    A61    2-methylphenyl         phenyl 2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         H   H    CH.sub.3                                      162.5-163.5                                            C.sub.30 H.sub.30                                            N.sub.2 O.sub.2                                                    A62    phenyl  4-     &#34;    &#34;   &#34;   &#34;    &#34;   297-299                                            C.sub.30 H.sub.30                                            N.sub.2 O.sub.2                                                    A         methylphenyl63    butyl   C.sub.2 H.sub.5                &#34;    &#34;   &#34;   Br   &#34;         C.sub.23 H.sub.31                                            BrN.sub.2 O.sub.2                                                    D64    phenylmethyl         CH.sub.3                H    H   &#34;   H    C.sub.2 H.sub.5                                      135-137                                            C.sub.22 H.sub.22                                            N.sub.2 O.sub.2                                                    B65    &#34;       &#34;      &#34;    &#34;   &#34;   &#34;    n-C.sub.3 H.sub.7                                      112-113                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    B66    butyl   &#34;      &#34;    &#34;   &#34;   &#34;    phenyl                                      181-183                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    B67    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   104-106                                            C.sub.26 H.sub.22                                            N.sub.2 O.sub.2                                                    B68    &#34;       &#34;      &#34;    &#34;   &#34;   &#34;    CF.sub.3                                      78-80 C.sub.21 H.sub.17                                            F.sub.3 N.sub.2 O.sub.2                                                    B69    butyl   &#34;      2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    C.sub.2 H.sub.5                                      112.5-114.5                                            C.sub.23 H.sub.32                                            N.sub.2 O.sub.2                                                    B70    phenylmethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   133.5-135                                            C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    B71    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   109-111                                            C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    B72    butyl   &#34;      &#34;    &#34;   &#34;   Br   &#34;   132.5-133.5                                            C.sub.23 H.sub.31                                            BrN.sub.2 O.sub.2                                                    D73    2-      CH.sub.3                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         H   Br   C.sub.2 H.sub.5                                      126-129.5                                            C.sub.27 H.sub.31                                            BrN.sub.2 O.sub.2                                                    D phenylethyl74    butyl   &#34;      &#34;    &#34;   &#34;   H    n-C.sub.3 H.sub.7                                            C.sub.24 H.sub.34                                            N.sub.2 O.sub.2                                                    B75    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.28 H.sub.34                                            N.sub.2 O.sub.                                                    B76    &#34;       &#34;      &#34;    &#34;   &#34;   &#34;    CF.sub.3                                      179-180                                            C.sub.26 H.sub.27                                            F.sub.3 N.sub.2 O.sub.2                                                    B77    butyl   &#34;      &#34;    &#34;   &#34;   &#34;    n-C.sub.4 H.sub.9                                            C.sub.25 H.sub.36                                            N.sub.2 O.sub.2                                                    B78    2-phenylethyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.29 H.sub.36                                            N.sub.2 O.sub.2                                                    B79    butyl   &#34;      &#34;    &#34;   phenyl                             &#34;    H   180-182                                            C.sub.27 H.sub.32                                            N.sub.2 O.sub.2                                                    F80    2-phenylethyl         &#34;      &#34;    &#34;   H   --(CH.sub.2)4--                                      188-190                                            C.sub.29 H.sub.34                                            N.sub.2 O.sub.2                                                    B81    phenylmethyl         &#34;      H    H   &#34;   phenyl                                  H   166-168                                            C.sub.26 H.sub.22                                            N.sub.2 O.sub.2                                                    F82    cyclohexyl-         C.sub.2 H.sub.5                &#34;    &#34;   &#34;   H    CH.sub.3  C.sub.22 H.sub.28                                            N.sub.2 O.sub.2                                                    A methyl83    4-methyl-         n-C.sub. 3 H.sub.7                &#34;    &#34;   &#34;   &#34;    &#34;   181-183                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    A phenylmethyl84    cyclohexyl-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.23 H.sub.30                                            N.sub.2 O.sub.2                                                    A methyl85    cyclohexyl-         n-C.sub.4 H.sub.9                H    H   H   H    CH.sub.3  C.sub.24 H.sub.32                                            N.sub.2 O.sub.2                                                    A methyl86    4-methyl-         iso-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A phenylmethyl87    cyclohexyl-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.32                                            N.sub.2 O.sub.2                                                    A methyl88    4-methyl-         n-C.sub.5 H.sub.11                &#34;    &#34;   &#34;   &#34;    &#34;   151-152.5                                            C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    A phenylmethyl89    phenylmethyl         C.sub.2 H.sub.5                2-CH.sub.3                     &#34;   &#34;   &#34;    &#34;         C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    A90    4-chloro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.23 H.sub.23                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl91    phenylmethyl         nC.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;   161-163.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A92    4-chloro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.25 H.sub.27                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl93    phenylmethyl         nC.sub.5 H.sub.11                &#34;    &#34;   &#34;   &#34;    &#34;   111.5-113                                            C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    A94    4-chloro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   155-156.5                                            C.sub.26 H.sub.29                                            ClN.sub.2 O.sub.2                                                    A phenylmethyl95    phenylmethyl         C.sub.2 H.sub.5                2-Cl &#34;   &#34;   &#34;    &#34;   174.5-177                                            C.sub.22 H.sub.21                                            ClN.sub.2 O.sub.2                                                    A96    phenylmethyl         nC.sub.3 H.sub.7                &#34;    &#34;   &#34;   &#34;    &#34;   171-171.5                                            C.sub.22 H.sub.23                                            ClN.sub.2 O.sub.2                                                    A97    phenylmethyl         nC.sub.4 H.sub.9                2-Cl H   H   H    CH.sub.3                                      121-123                                            C.sub.24 H.sub.25                                            ClN.sub.2 O.sub.2                                                    A98    phenylmethyl         nC.sub.3 H.sub.7                2-CH.sub.3                     3-CH.sub.3                         &#34;   &#34;    &#34;   126-128                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    A99    phenylmethyl         methoxy-                H    H   &#34;   &#34;    &#34;         C.sub.22 H.sub.22                                            N.sub.2 O.sub.3                                                    A         methyl100   phenylmethyl         2-methyl-                &#34;    &#34;   &#34;   &#34;    &#34;   173-174                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A         phenyl101   phenylmethyl         3-methyl-                &#34;    &#34;   &#34;   &#34;    &#34;   202.5-204.5                                            C.sub.27 H.sub.24                                            N.sub.2 O.sub.2                                                    A         phenyl102   phenylmethyl         2-chloro-                &#34;    &#34;   &#34;   &#34;    &#34;   194-196                                            C.sub.26 H.sub.21                                            ClN.sub.2 O.sub.2                                                    A         phenyl103   phenylmethyl         2-furyl                &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.20                                            N.sub.2 O.sub.3                                                    A104   methyl  nC.sub.4 H.sub.9                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    &#34;   95.5-96                                            C.sub.22 H.sub.30                                            N.sub.2 O.sub.2                                                    B105   methyl  &#34;      &#34;    &#34;   &#34;   Br   &#34;   180-180.5                                            C.sub.22 H.sub.29                                            BrN.sub.2 O.sub.                                                    D106   methyl  &#34;      &#34;    &#34;   &#34;   CH.sub.3                                  CH.sub.3                                      114.5-115.5                                            C.sub.23 H.sub.32                                            N.sub.2 O.sub.2                                                    B107   methyl  &#34;      &#34;    &#34;   4-Br                             H    &#34;   170.5-171.0                                            C.sub.22 H.sub.29                                            BrN.sub.2 O.sub.2                                                    B108   methyl  &#34;      &#34;    &#34;   &#34;   Br   &#34;   179.5-180                                            C.sub.22 H.sub.28                                            Br.sub.2 N.sub.2                                                    D.sub.2109   methyl  nC.sub.4 H.sub.9                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         4-Br                             CH.sub.3                                  CH.sub.3                                      139.0-140.0                                            C.sub.23 H.sub.31                                            BrN.sub.2 O.sub.2                                                    B110   methyl  nC.sub.3 H.sub.7                &#34;    &#34;   H   &#34;    &#34;   148-150.5                                            C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    B111   methyl  &#34;      &#34;    &#34;   4-Br                             &#34;    &#34;   156.0-156.5                                            C.sub.26 H.sub.29                                            BrN.sub.2 O.sub.2                                                    B112   methyl  nC.sub.5 H.sub.11                &#34;    &#34;   H   H    &#34;   98-98.5                                            C.sub.24 H.sub.34                                            N.sub.2 O.sub.2                                                    B113   3-chlorophenyl         nC.sub.4 H.sub.9                H    H   &#34;   &#34;    &#34;   210-211                                            C.sub.23 H.sub. 23                                            ClN.sub.2 O.sub.2                                                    B114   3-bromophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   204-205                                            C.sub.23 H.sub.23                                            BrN.sub.2 O.sub.2                                                    B115   3,5-bistri-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   248-249                                            C.sub.25 H.sub.22                                            F.sub.6 N.sub.2 O.sub.2                                                    B fluoromethyl- phenyl116   3-trifluoro         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   175-176                                            C.sub.24 H.sub.23                                            F.sub.3 N.sub.2 O.sub.2                                                    B methylphenyl117   3-methylphenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   110.5-111                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    B118   3-iodophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   211.5-216.5                                            C.sub.23 H.sub.23                                            IN.sub.2 O.sub.2                                                    B119   3-fluorophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   185.5-187                                            C.sub.23 H.sub.23                                            FN.sub.2 O.sub.2                                                    B120   3-ethylphenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   142-142.5                                            C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    B121   3,5-dichloro-         nC.sub.4 H.sub.9                H    H   H   H    CH.sub.3                                      218-218.5                                            C.sub.23 H.sub.22                                            Cl.sub.2 N.sub.2                                                    B.sub.2 phenyl122   3-methoxyphenyl         n-C.sub.4 H.sub.9                &#34;    &#34;   &#34;   &#34;    &#34;   140-142                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.3                                                    B123   2,3-dichloro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   178-180                                            C.sub.23 H.sub.22                                            ClN.sub.2 O.sub.2                                                    B phenyl124   3,4-dichloro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   199.5-200.0                                            C.sub.23 H.sub.22                                            Cl.sub.2 N.sub.2                                                    B.sub.2 phenyl125   3-chlorophenyl         &#34;      2-CH.sub.3                     3-CH.sub.3                         &#34;   &#34;    &#34;   123-124                                            C.sub.25 H.sub.27                                            ClN.sub.2 O.sub.2                                                    B126   3-chlorophenyl         &#34;      2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    &#34;   178-178.5                                            C.sub.27 H.sub.31                                            ClN.sub.2 O.sub.2                                                    B127   3-chlorophenyl         phenyl &#34;    &#34;   &#34;   &#34;    &#34;   242-243                                            C.sub.29 H.sub.27                                            ClN.sub.2 O.sub.2                                                    B128   H       nC.sub.4 H.sub.9                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         H   H    CH.sub.3                                      oil   C.sub.21 H.sub.28                                            N.sub.2 O.sub.2                                                    B129   H       3-bromo-                H    H   &#34;   &#34;    &#34;   286.5-289                                            C.sub.19 H.sub.15                                            BrN.sub.2 O.sub.2                                                    B         phenyl130   methyl  nC.sub.3 H.sub.7                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    &#34;   99.5-100.5                                            C.sub.21 H.sub.28                                            N.sub.2 O.sub.2                                                    B131   methyl  &#34;      &#34;    &#34;   4-Br                             &#34;    &#34;   159.0-160.0                                            C.sub.21 H.sub.27                                            BrN.sub.2 O.sub.2                                                    B132   methyl  &#34;      &#34;    &#34;   4-I &#34;    &#34;         C.sub.21 H.sub.27                                            IN.sub.2 O.sub.2                                                    B133   methyl  nC.sub.3 H.sub.7                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         4-OCH.sub.3                             H    CH.sub.3  C.sub.22 H.sub.30                                            N.sub.2 O.sub.3                                                    B134   methyl  &#34;      &#34;    &#34;   4-C.sub.2 H.sub.5                             &#34;    &#34;         C.sub.23 H.sub.32                                            N.sub.2 O.sub.2                                                    B135   methyl  3-chloro-                H    H   H   &#34;    &#34;   191.0-192.5                                            C.sub.20 H.sub.17                                            ClN.sub.2 O.sub.2                                                    B         phenyl136   ethyl   nC.sub.4 H.sub.9                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         4-Br                             &#34;    &#34;   143.5-145                                            C.sub.23 H.sub.31                                            BrN.sub.2 O.sub.2                                                    B137   H       &#34;      &#34;    &#34;   H   Br   CH.sub.3                                      163-166                                            C.sub.21 H.sub.27                                            BrN.sub.2 O.sub.2                                                    D138   methyl  nC.sub.3 H.sub.7                &#34;    &#34;   &#34;   &#34;    &#34;   183-184.5                                            C.sub.21 H.sub.27                                            BrN.sub.2 O.sub.2                                                    D139   methyl  &#34;      &#34;    &#34;   4-Br                             &#34;    &#34;   204-205                                            C.sub.21 H.sub.26                                            Br.sub.2 N.sub.2                                                    D.sub.2140   methyl  &#34;      &#34;    &#34;   4-C.sub.2 H.sub.5                             &#34;    &#34;   169-173.5                                            C.sub.23 H.sub.31                                            BrN.sub.2 O.sub.2                                                    D141   ethyl   nC.sub.4 H.sub.9                &#34;    &#34;   4-Br                             &#34;    &#34;   210-210.5                                            C.sub.23 H.sub.30                                            Br.sub.2 N.sub.2                                                    D.sub.2142   methyl  nC.sub.3 H.sub.7                &#34;    &#34;   4-C.sub.2 H.sub.5                             CH.sub.3                                  &#34;         C.sub.24 H.sub.34                                            N.sub.2 O.sub.2                                                    B143   methyl  &#34;      &#34;    &#34;   4-I &#34;    &#34;         C.sub.22 H.sub.29                                            IN.sub.2 O.sub.2                                                    B144   methyl  nC.sub.4 H.sub.9                &#34;    &#34;   4-Br                             C.sub.2 H.sub.5                                  &#34;   oil   C.sub.24 H.sub.33                                            BrN.sub.2 O.sub.2                                                    B145   methyl  nC.sub.3 H.sub.7                2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         H   H    C.sub.2 H.sub.5                                            C.sub.22 H.sub.30                                            N.sub.2 O.sub.2                                                    B146   methyl  nC.sub.4 H.sub.9                &#34;    &#34;   4-Br                             CH.sub.3                                  &#34;         C.sub.24 H.sub.33                                            BrN.sub.2 O.sub.2                                                    B147   phenyl  &#34;      H    H   H   H    CH.sub.3                                      213.0-214.0                                            C.sub.23 H.sub.24                                            N.sub.2 O.sub.2                                                    B148   2-methylphenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   183.0-185.0                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    B149   2-chlorophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   153.0-154.0                                            C.sub.23 H.sub.23                                            ClN.sub.2 O.sub.2                                                    B150   methyl  phenyl 2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   CH.sub.3                                  &#34;         C.sub.25 H.sub.28                                            N.sub.2 O.sub.2                                                    B151   3-cyanophenyl         nC.sub.4 H.sub.9                H    H   &#34;   H    &#34;   207.5-209.5                                            C.sub.24 H.sub.23                                            N.sub.3 O.sub.2                                                    B152   3-nitrophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   184.5-186                                            C.sub.23 H.sub.23                                            N.sub.3 O.sub.4                                                    B153   4-chlorophenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   192.0-192.5                                            C.sub.23 H.sub.23                                            ClN.sub.2 O.sub.2                                                    B154   4-methylphenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   163.5-165.0                                            C.sub.24 H.sub.26                                            N.sub.2 O.sub.2                                                    B155   3-chloro-2-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   163.0-164.0                                            C.sub.24 H.sub.25                                            ClN.sub.2 O.sub.2                                                    B methylphenyl156   3-chloro-4-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.24 H.sub.25                                            ClN.sub.2 O.sub.2                                                    B methylphenyl157   5-chloro-2-         nC.sub.4 H.sub.9                H    H   H   H    CH.sub.3  C.sub.24 H.sub.25                                            ClN.sub.2 O.sub.2                                                    B methylphenyl158   3-pyridyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.22 H.sub.23                                            N.sub.3 O.sub.2                                                    B159   3-bromophenyl         &#34;      2-CH.sub.3                     3-CH.sub.3                         &#34;   &#34;    &#34;   157.5-158.0                                            C.sub.25 H.sub.27                                            BrN.sub.                                                    B O.sub.2160   3-methylphenyl         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   165.0-166.5                                            C.sub.26 H.sub.30                                            N.sub.2 O.sub.2                                                    B161   3-trifluoro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;   157.5-158.0                                            C.sub.26 H.sub.27                                            F.sub.3 N.sub.2 O.sub.2                                                    B methylphenyl162   3-bromophenyl         &#34;      2-C.sub.2 H.sub.5                     6-C.sub.2 H.sub.5                         &#34;   &#34;    &#34;   136.5-137.5                                            C.sub.27 H.sub.31                                            BrN.sub.2 O.sub.2                                                    B163   3-trifluoro-         &#34;      &#34;    &#34;   &#34;   &#34;    &#34;         C.sub.28 H.sub.31                                            F.sub.3 N.sub.2 O.sub.2                                                    B methylphenyl164   methyl  n-C.sub.3 H.sub.7                &#34;    &#34;   &#34;   Br   C.sub.2 H.sub.5                                            C.sub.22 H.sub.29                                            BrN.sub.2 O.sub.2                                                    D165   methyl  &#34;      &#34;    &#34;   4-OCH.sub.3                             &#34;    CH.sub.3  C.sub.22 H.sub.29                                            BrN.sub.2 O.sub.3                                                    D166   methyl  &#34;      &#34;    &#34;   I   &#34;    &#34;         C.sub.21 H.sub.26                                            BrIN.sub.2 O.sub.2                                                    D__________________________________________________________________________ 
    
     
                                           TABLE 2__________________________________________________________________________                                   EvaluationExampleIR           NMR                   Conc.                                       PlantsNo.  ν value (cm.sup.-1)        Method             Chemical shift δ value                            Solvent                                   (ppm)                                       X Y Z__________________________________________________________________________1    1617,   KBr  1.40 (3H,t), 2.26 (3H,s),                            CDCl.sub.3                                    20 4 4 11663         3.40 (2H,q), 5.22 (2H,s),                                   100 4 4 2             6.43 (1H,s),             6.70-7.75(10H,m),             12.76(1H,br)2    1600,   KBr  1.37 (3H,t), 2.26 (3H,s),                            &#34;       20 4 4 11638,        2.32 (3H,s), 3.25 (2H,q),                                   100 4 4 11664         5.18 (2H,s), 6.43 (1H,s),             6.60-7.75 (9H,m),             12.83 (1H,br)3    1630,   KBr  1.04 (6H,t), 0.7-2.0 (6h,m),                            &#34;       20 3 4 31675         2.31 (3H,s), 3.27 (2H,t),                                   100 3 4 3             3.87 (2H,t), 6.31 (1H,s),             6.90-7.60 (5H,m),             12.60 (1H,br)4    1627,   KBr  0.98 (3H,t), 1.80 (2H,six),                            &#34;        20                                       4 4 11667         2.24 (3H,s), 3.18 (2H,t),                                   100 4 4 1             5.16 (2H,s), 6.40 (1H,s),             6.70-7.70 (10H,m),             12.75 (1H,br)5    1625,   KBr  1.07 (3H,t), 1.63 (2H,six),                            &#34;       20 3 4 11673         2.31 (3H,s), 2.91 (2H,t),                                   100 3 4 1             3.36 (2H,t), 4.10 (2H,t),             6.32 (1H,s), 6.90-7.70 (10H,m),             12.69 (1H,br)6    1630,   KBr  0.89 (3H,t), 1.00-2.00 (4H,m),                            CDCl.sub.3                                    20 4 4 11675         2.25 (3H,s), 3.22 (2H,t),                                   100 4 4 2             5.19 (2H,s), 6.41 (1H,s),             6.70-7.70 (10H,m), 12.70 (1H,br)7    1640,   KBr  0.92 (3H,t), 1.10-2.20 (4H,m),                            &#34;       20 4 4 11665         2.24 (3H,s), 2.30 (3H,s),                                   100 4 4 1             3.25 (2H,t), 5.15 (2H,s),             6.41 (1H,s), 6.70-7.75 (9H,m),             12.74 (1H,br)8    1620,   KBr  0.95 (6H,d), 2.90 (1H,m),                            &#34;       20 4 4 11660         2.23 (3H,s), 3.46 (2H,d),                                   100 4 4 1             5.20 (2H,s), 6.41 (1H,s),             6.70-7.70 (10H,m),             12.42 (1H,br)9    1627,   KBr  0.87 (3H,t,), 1.00-2.10 (6H,m),                            &#34;       20 4 4 11670         2.22 (3H,s), 3.23 (2H,t),                                   100 4 4 1             5.16 (2H,s), 6.40 (1H,s),             6.70-7.70 (10H,m),             12.63 (1H,br)10   1637,   KBr  0.83 (3H,t), 1.00-2.00 (10H,m),                            &#34;       20 3 4 11663         2.22 (3H,s), 3.20 (2H,t),                                   100 4 4 1             5.14 (2H,s), 6.36 (1H,s),             6.70-7.75 (10H,m),             12.70 (1H,br)11   1600,   Neat 0.86 (3H,t), 0.90-2.00 (14H,m),                            CDCl.sub.3                                    20 3 4 11630,        2.24 (3H,s), 3.20 (2H,t),                                   100 3 4 11670         5.18 (2H,s), 6.40 (1H,s),             6.70-7.70 (10H,m), 12.65 (1H,br)12   1623,   KBr  2.23 (3H,s), 4.70 (2H,s),                            &#34;       20 1 4 11660         5.00 (2H,s), 6.47 (1H,s),                                   100 1 4 1             6.60-7.65 (15H,m),             12.83 (1H,br)13   1627,   KBr  2.20 (3H,s), 2.31 (3H,s),                            &#34;       20 2 4 11657         4.73 (2H,s), 5.00 (2H,s),                                   100 2 4 1             6.50 (1H,s), 6.65-7.70 (15H,m),             12.83 (1H,br)14   1610,   KBr                         20 1 3 11640,                              100 2 4 1166015   1625,   KBr  2.36 (3H,s), 3.14 (3H,s),                            CDCl.sub.3                                    20 2 3 31663         6.51 (1H,s),          100 2 4 5             6.85-7.60 (10H,m),             12.53 (1H,br)16   1617,   KBr  1.06 (3H,t), 2.42 (3H,s),                            CDCl.sub.3                                    20 1 4 11663         3.68 (2H,q), 6.51 (1H,s),                                   100 4 4 1             6.90-7.60 (10H,m),             12.45 (1H,br)17   1617,   KBr  0.59 (3H,t), 1.45 (2H,six),                            &#34;       20 4 4 11677         2.40 (3H,s), 3.48 (2H,t),                                   100 4 4 1             6.48 (1H,s), 6.80-7.65 (10H,m),             12.50 (1H,br)18   1600,   KBr  0.66 (3H,t), 0.50-1.80 (4H,m),                            &#34;       20 3 4 11617,        2.40 (3H,s), 3.58 (2H,t),                                   100 3 4 21680         6.51 (1H,s), 6.60- 7.65 (10H,m),             12.49 (1H,br)19   1617,   KBr  0.71 (3H,t), 0.50-1.70 (6H,m),                            &#34;       20 4 4 11675         2.38 (3H,s), 3.50 (2H,t),                                   100 4 4 3             6.32 (1H,s), 6.80-7.50 (10H,m),             12.53 (1H,br)20   1617,   KBr  0.77 (3H,t), 0.50-1.80 (8H,m),                            &#34;       20 4 4 11675         2.41 (3H,s), 3.57 (2H,t),                                   100 4 4 1             6.51 (1H,s), 6.85-7.60 (10H,m),             12.57 (1H,br)21   1600,   KBr  0.58 (3H,t), 0.40-1.60 (12H,m),                            CDCl.sub.3                                    20 4 4 11620,        2.38 (3H,s), 3.66 (2H,t),                                   100 4 4 11680         6.43 (1H,s), 6.80-7.50 (10H,m),             12.07 (1H,br)22   1617,   KBr  1.67 (2H,m), 2.40 (3H,s),                            &#34;       20 3 4 11677         3.00 (2H,t), 3.12 (3H,s),                                   100 3 5 1             3.70 (2H,t), 6.48 (1H,s),             6.80-7.60 (10H,m), 12.46 (1H,br)23   1623,   KBr  2.44 (3H,s), 3.12 (3H,s),                            &#34;       20 4 4 11670         3.22 (2H,t), 3.85 (2H,t),                                   100 4 4 1             6.48 (1H,s), 6.80-7.60 (10H,m),             12.35 (1H,br)24   1623,   KBr                        20  1 4 11675                               100 1 4 125   1620,   KBr  2.27 (3H,s), 4.89 (2H,s)                            CDCl.sub.3                                    20 4 4 11675         6.59 (1H,s), 6.55-7.60 (15H,m),                                   100 4 4 1             12.46 (1H,br)26   1620,   KBr  2.25 (3H,s), 2.28 (3H,s),                            CDCl.sub.3                                    20 4 4 11673         4.79 (2H,s), 6.55 (1H,s),                                   100 4 4 1             6.50-7.60 (14H,m),             12.48 (1H,br)27   1625,   KBr  2.25 (3H,s), 4.80 (2H,s),                            &#34;       20 4 4 11665         6.58 (1H,s),          100 4 4 1             6.55-7.60 (14H,m),             12.38 (1H,br)28   1613,   KBr  2.42 (3H,s), 2.68 (2H,t),                            &#34;       20 1 4 11673         3.80 (2H,t), 6.52 (1H,t),                                   100 3 4 1             6.50-7.60 (15H,m),             12.43 (1H,br)29   1623,   KBr  2.43 (3H,s), 4.78 (2H,s),                            &#34;       20 4 4 11673         5.75 (1H,m), 6.20 (1H,dd),                                   100 4 4 1             6.50 (1H,s), 6.80-7.55 (11H,m),             12.35 (1H,br)30   1617,   KBr  2.30 (3H,s), 4.91 (2H,s),                            &#34;       20 4 4 11667         6.58 (1H,s),          100 4 4 1             6.50-8.45 (14H,m),             12.53 (1H,br)31   1615,   KBr  2.30 (3H,s), 4.82 (2H,s),                            CDCl.sub.3                                    20 4 4 11665         6.59 (1H,s),          100 4 4 1             6.60-7.60 (14H,m),             12.60 (1H,br)32   1623,   KBr  2.26 (3H,s), 4.82 (2H,s),                            &#34;1670         6.57 (1H,s),             6.55-7.60 (14H,m),             12.55 (1H,br)33   1623,   KBr  2.22 (3H,s), 2.30 (3H,s)                            &#34;       20 3 4 11673         4.82 (2H,s), 6.52 (1H,s),                                   100 3 4 1             6.55-7.60 (14H,m),             12.39 (1H,br)34   1625,   Neat 2.23 (3H,s), 4.86 (2H,s)                            &#34;       20 4 4 11675         6.18 (1H,m), 6.35 (1H,dd),                                   100 4 4 3             6.57 (1H,s), 6.70-7.70 (11H,m),             12.30 (1H,br)35   1623,   KBr  1.00 (3H,t), 1.75 (2H,six),                            &#34;       20 4 4 11660         2.24 (3H,s), 2.40 (3H,s),                                   100 4 4 1             3.20 (2H,t), 5.17 (2H,s),             6.39 (1H,s), 5.17 (2H,s),             12.43 (1H,br)36   1630,   KBr  1.00 (3H,t), 1.75 (2H,six)                            CDCl.sub.3                                    20 4 4 11675         2.21 (3H,s), 2.39 (3H,s),                                   100 4 4 2             3.20 (2H,t), 5.11 (2H,s),             6.38 (1H,s), 6.70-8.05 (8H,m).             12.50 (1H,br)37   1627,   KBr  1.06 (3H,t), 1.75 (2H,six),                            &#34;       20 4 4 21653         2.30 (3H,s), 2.37 (3H,s)                                   100 4 4 2             2.90 (2H,t), 3.40 (2H,t),             4.08 (2H,t), 6.30 (1H,s),             6.80-8.00 (9H,m), 12.50 (1H,br)38   1610,   KBr  0.66 (3H,t), 0.50-1.80( 4H,m),                            &#34;       20 4 4 11675         2.32 (3H,s), 2.39 (3H,s),                                   100 4 4 3             3.50 (2H,t), 6.51 (1H,s),             6.80-7.90 (9H,m),             12.25 (1H,br)39   1623,   KBr  2.27 (3H,s), 2.36 (3H,s),                            &#34;       20 4 4 11667         4.83 (2H,s), 6.57 (1H,s),                                   100 4 4 2             6.55-7.84 (14H,m),             12.28 (1H,br)40   1623,   KBr  2.27 (3H,s), 2.35 (3H,s),                            &#34;       20 3 4 11673         4.81 (2H,s), 6.57 (1H,s),                                   100 4 4 2             6.55-7.85 (13H,m),             12.21 (1H,br)41   1623,   KBr  0.65 (3H,t), 0.40-1.80 (4H,m),                            CDCl.sub.3                                    20 4 4 11680         2.41 (3H,t), 3.52 (2H,t),                                   100 4 4 1             6.50 (1H,t), 6.70-8.17 (9H,m),             12.90 (1H,br)42   1607,   KBr  0.65 (3H,t), 0.40-1.80 (4H,m)                            CDCl.sub.3                                    20 4 4 11680         2.12 (3H,t), 2.21 (3H,t),                            +      100 4 4 1             2.43 (3H,t), 3.62 (2H,t),                            DMSO-d.sup.6             6.46 (1H,t), 6.70-7.50 (8H,t),             11.63 (1H,br)43   1605,   KBr  2.20 (6H,t), 2.23 (3H,t),                            CDCl.sub.3                                    20 4 4 11617,        4.81 (2H,s), 6.53 (1H,t),                                   100 4 4 11677         6.50-7.60 (13H,m),             12.05 (1H,m)44   1603,   KBr  2.20 (6H,ms), 2.42 (3H,t),                            &#34;       20 1 2 11625         2.66 (2H,t), 3.80 (2H,t)                                   100 1 3 11675         6.50 (1H,t), 6.50-7.60 (13H,m),             12.00 (1H,br)45   1620,   KBr  0.67 (3H,t), 0.40-1.80 (4H,m),                            &#34;       20 3 4 51675         2.20 (6H,t), 2.40 (3H,t),                                   100 3 4 5             3.60 (2H,t), 6.49 (1H,t),             6.87-7.20 (8H,m), 11.13 (1H,br)46   1625,   KBr  2.10 (6H,s), 2.24 (3H,s),                            CDCl.sub.3                                    20 4 4 11650         4.84 (2H,s), 6.60 (1H,s),                                   100 4 4 1             6.60-7.30 (13H,m),             11.05 (1H,br)47   1630,   KBr  1.06 (3H,t), 1.18 (6H,t),                            &#34;       20 1 2 41675         0.75-2.10 (4H,m), 2.35 (3H,s),                                   100 1 2 4             2.63 (4H,q), 3.89 (2H,t),             6.43 (1H,s), 7.25 (3H,s),             8.44 (1H,s), 11.80 (1H,br)48   1630,   Neat 1.20 (6H,t), 0.70-2.00 (10H,m),                            &#34;       20 3 3 51660    Neat 2.40 (3H,s), 2.65 (4H,q),                                   100 5 4 5             3.35 (2H,q), 3.90 (2H,t),             6.37 (1H,s), 7.03 (3H,s),             11.80 (1H,br)49   1630,   Neat 1.20 (6H,t), 1.33 (3H,t),                            &#34;       20 1 2 31660         2.27 (3H,s), 2.70 (4H,q),                                   100 3 4 5             3.30 (2H,q), 5.23 (2H,s),             6.49 (1H,s), 6.80-7.50 (8H,m),             11.81 (1H,br)50   1630,   Neat 1.19 (6H,t), 1.21 (3H,t),                            &#34;       20 5 5 51650         2.35 (3H,s), 2.66 (4H,q),                                   100 5 5 5             2.95 (2H,t), 3.37 (2H,q),             4.15 (2H,t), 6.39 (1H,s),             7.00-7.40 (8H,m), 11.70 (1H,br)51   1625,   KBr  1.18 (6H,t), 0.80-2.10 (10H,m),                            CDCl.sub.3                                    20 1 1 31660         2.37 (3H,s), 2.67 (4H,q),                                   100 4 4 4             3.30 (H,t), 3.85 (2H,t),             6.39 (1H,s), 7.03 (3H,s),             11.80 (1H,br)52   1627,   Neat 1.17 (6H,t), 0.60-2.00 (12H,m),                            &#34;       20 2 3 51650,        2.37 (3H,s), 2.65 (4H,q),                                   100 4 4 51663         3.20 (2H,t), 3.90 (2H,t),             6.37(1H,s), 7.03 (3H,s),             11.82 (1H,br)53   1630,   KBr  0.95 (3H,t), 1.19 (6H,t),                            &#34;       20 3 4 11665         1.70 (2H,six), 2.26 (3H,s),                                   100 3 4 4             2.70 (4H,q), 3.23 (2H,t),             5.18 (2H,s), 6.44 (1H,s),             6.80-7.50 (8H,m), 11.80 (1H,br)54   1630,   Neat 1.18 (6H,t), 0.60-2.00 (14H,m),                            &#34;       20 2 1 41665         2.38 (3H,s), 2.65 (4H,q),                                   100 4 4 4             3.23 (2H,t), 3.92 (2H,t),             6.39 (1H,s), 7.03 (3H,s),             11.78 (1H,br)55   1647    Neat 0.98 (6H,d), 1.17 (6H,t),                            &#34;       20 1 2 4             0.50-2.00 (8H,m), 2.39 (3H,s),                                   100 5 5 4             2.65 (4H,q), 3.22 (2H,d),             3.95 (2H,t), 6.38 (1H,s),             7.02 (3H,s), 12.05 (1H,s),56   1630,   Neat 0.91 (3H,t), 1.10 (6H,t),                            CDCl.sub.3                                    20 3 4 51660         0.70-2.00 (4H,m), 2.36 (3H,s),                                   100 5 4 5             2.55 (4H,q), 3.80 (2H,t),             4.93 (2H,s), 6.46 (2H,s),             7.00-7.35 (8H,m), 12.70 (1H,br)57   1620,   KBr  0.59 (3H,t), 1.10 (6H,t),                            &#34;       20 2 4 41667         0.50-1.80 (4H,m), 2.43 (3H,s),                                   100 4 4 4             2.50 (4H,q), 3.62 (2H,t),             6.53 (1H,s), 7.00-7.50 (8H,m),             11.06 (1H,br)58   1623,   KBr                         20 4 4 11673                               100 4 4 159   1625,   KBr  1.10 (6H,t), 2.29 (3H,s),                            CDCl.sub.3                                    20 4 4 11667         2.50 (4H,q), 4.91 (2H,s),                                   100 4 4 3             6.60 (1H,s), 6.60-7.40 (13H,m),             10.98 (1H,br)60   1620,   KBr  1.10 (6H,t), 2.44 (3H,s),                            &#34;       20 1 1 11660         2.50 (4H,q), 2.67 (2H,t),                                   100 1 2 1             3.83 (2H,t), 6.50 (1H,s),             6.50-7.40 (13H,m), 11.02 (1H,br)61   1600,   KBr  1.10 (6H,t), 1.90 (3H,s),                            CDCl.sub.3                                    20 3 4 31620,        2.02 (3H,s), 2.52 (4H,q),                                   100 3 4 41665         6.59 (1H,s), 6.80-7.10 (12H,m),             11.02 (1H,br)62   1620,   KBr                         20 2 3 11673                               100 3 4 163   1660    Neat 1.18 (6H,t), 0.80- 2.00 (10H,m),                            CDCl.sub.3                                    20 4 5 5             2.65 (4H,q), 2.74 (3H,s),                                   100 5 5 5             3.32 (2H,q), 4.06 (2H,t),             7.10 (3H,s), 11.20 (1H,br)64   1625,   KBr  1.19 (3H,t), 2.51 (2H,q),                            &#34;       20 4 4 21660         2.82 (3H,s), 5.16 (2H,s),                                   100 4 4 2             6.43 (1H,s), 6.70-7.75 (10H,m),             12.68 (1H,br)65   1600,   KBr  0.93 (3H,t), 1.65 (2H,six),                            &#34;       20 3 3 11620,        2.45 (2H,t), 2.87 (3H,s),                                   100 3 3 11673         5.25 (2H,s), 6.40 (1H,s),             6.70-7.75 (10H,m),             12.70 (1H,br)66   1600,   KBr  0.62 (3H,t), 0.50-1.80 (4H,m),                            CDCl.sub.3                                    201630,        2.95 (3H,s), 3.85 (2H,t),                                   1001665         6.36 (1H,s), 6.90-7.75 (10H,m),             12.60 (1H,br)67   1600,   KBr  2.85 (3H,s), 5.09 (2H,s),                            &#34;       20 1 1 11615,        6.47 (1H,s), 6.64-7.75 (15H,m),                                   100 2 1 21665         12.53 (1H,br)68   1607,   KBr  2.76 (3H,s), 5.30 (2H,s),                            &#34;       20 2 4 11630,        6.47 (1H,s),          100 3 4 11680         6.72-7.75 (10H,m),             11.62 (1H,br)69   1620.   KBr  1.19 (6H,t), 0.80-2.00 (10H,m),                            &#34;       20 4 4 51650         2.65 (6H,q), 2.90 (3H,s),                                   100 5 5 5             3.93 (2H,t), 6.42 (1H,s),             7.06 (3H,s), 11.71 (1H,br)70   1625,   KBr  1.18 (6H,t), 1.22 (3H,t),                            &#34;       20 1 1 41660         2.55 (2H,q), 2.65 (4H,q),                                   100 3 4 4             2.79 (3H,s), 5.20 (2H,s),             6.49 (1H,s), 6.80-7.50 (8H,m),             11.80 (1H,br)71   1627,   KBr  1.19 (6H,t), 1.27 (3H,t),                            CDCl.sub.3                                    20 4 5 51650    KBr  2.63 (2H,q), 2.65 (4H,q),                                   100 5 5 5             2.92 (3H,s), 2.90 (2H,t),             4.18 (2H,t), 6.42 (1H,s),             7.00-7.30 (8H,m), 11.75 (1H,br)72   1605,   KBr  1.18 (6H,t), 0.80-2.00 (10H,m),                            &#34;       20 1 2 51650         2.65 (4H,q), 2.84 (3H,s),                                   100 4 4 5             3.08 (2H,q), 4.00 (2H,t),             7.06 (3H,s), 11.05 (1H,br)73   1615,   KBr  1.16 (6H,t), 1.27 (3H,t),                            &#34;       20 4 5 51645,        2.65 (4H,q), 2.85 (3H,s),                                   100 5 5 51665         3.00 (2H,t), 3.05 (2H,q),             4.22 (2H,t), 6.95-7.30 (8H,m),             10.89 (1H,br)74   1630,   KBr  1.18 (6H,t), 0.80-2.00 (12H,m)                            &#34;       20 2 3 51660         2.60 (2H,t), 2.65 (4H,q),                                   100 5 5 5             2.86 (3H,s), 3.90 (2H,t),             6.38 (1H,s), 7.02 (3H,s),             11.72 (1H,br)75   1625,   KBr  1.00 (3H,t), 1.19 (6H,t), 1.20-                            &#34;       20 1 1 31660         1.70 (2H,m), 2.52 (2H,t), 2.63                                   100 2 3 4             (4H,q), 2.89( 3H,s), 2.95 (2H,t),             4.11 (2H,t), 6.38 (1H,s),             6.95-7.30 (8H,m), 11.57 (1H,br)76   1630,   KBr  1.18 (6H,t), 2.63 (4H,q),                            CDCl.sub.3                                    20 4 4 31653         2.96 (3H,s), 3.00 (2H,t),                                   100 5 5 3             4.23 (2H,t), 6.97 (1H,s),             6.95-7.30 (8H,m), 10.88 (1H,br)77   1630,   KBr  1.20 (6H,t), 0.80-2.00 (14H,m),                            &#34;       20 1 1 31660         2.60 (2H,t), 2.65 (4H,q),             2.86 (3H,s), 3.93 (2H,t),             6.40 (1H,s), 7.05 (3H,s),             11.73 (1H,br)78   1625,   KBr  1.20 (6H,t), 0.80-1.80 (7H,m),                            &#34;       20 1 2 41660         2.60 (2H,t), 2.67 (4H,q),                                   100 2 2 4             2.93 (3H,s), 2.97 (2H,t)             4.15 (2H,t), 6.41 (1H,s),             7.00-7.40 (8H,m), 11.61 (1H,br)79   1655    KBr  1.17 (6H,t), 0.80-2.00 (7H,m),                            &#34;       20 1 2 1             2.65 (4H,q), 2.83 (3H,s),                                   100 2 2 1             3.92 (2H,t), 7.02 (3H,s),             7.10-7.60 (6H,m), 11.57 (1H,br)80   1620,   KBr  1.19 (6H,t), 1.70 (4H,m),                            &#34;       20 1 3 41650         2.62 (4H,m), 2.67 (4H,q),                                   100 2 3 4             2.93 (3H,s), 2.95 (2H,t),             4.20 (2H,t), 7.00-7.40 (8H,m),             11.72 (1H,br)81   1630,   KBr  2.79 (3H,s), 5.10 (2H,s),                            CDCl.sub.3                                    20 1 1 11650,        6.80-7.70 (16H,m),    100 1 2 11670         12.60 (1H,br)82                0.80-2.00 (13H,m), 1.28 (3H,s),                            &#34;       20 4 4 1             2.36 (3H,ms), 3.80 (2H,d),                                   100 4 4 1             6.35 (1H,s), 6.80-7.80 (5H,m),             12.66 (1H,br)83   1630,   KBr                         20 4 4 11673                               100 4 4 184                0.70-2.10(18H,m), 2.36 (3H,s),                            CDCl.sub.3                                    20 4 4 2             3.78 (2H,d), 6.36 (1H,s),                                   100 4 4 2             6.80-7.75 (5H,m), 12.57 (1H,br)85   1625,   Neat 0.50-2.10 (20H,m), 2.34 (3H,s),                            &#34;       20 3 4 11670         3.75 (2H,d), 6.30 (1H,s),                                   100 4 4 1             6.80-7.70 (5H,m), 12.60 (1H,br)86   1630,   Neat 0.97 (6H,d), 1.70-2.30 (3H,m),                            CDCl.sub.3                                    20 4 4 11663         2.25 (3H,s), 2.31 (3H,s),                                   100 4 4 1             3.50 (2H,d), 5.65 (2H,d),             6.40 (1H,s), 6.70-7.70 (9H,m),             12.45 (1H,br)87   1623,   Neat 0.60-2.30 (14H,m), 0.95 (6H,d),                            &#34;       20 4 4 21663         2.32 (3H,s), 3.82 (2H,d),                                   100 4 4 2             6.33 (1H,s), 6.80-7.70 (5H,m),             12.38 (1H,br)88   1600,   KBr                         20 4 4 11645,                              100 3 4 1166789   1630,   KBr                         20 4 4 41667                               100 4 4 490   1633,   Neat                        20 4 4 11667                               100 4 4 391   1613,   KBr                         20 4 4 11627,                              100 4 4 1166792   1633,   Neat 0.70-2.00 (7H,m), 2.22 (3H,s),                            CDCl.sub.3                                    20 4 4 11667         2.39 (3H,s), 3.20 (2H,t),                                   100 4 4 1             5.13 (2H,s), 6.40 (1H,s),             6.70-8.07 (8H,m), 12.47 (1H,br)93   1610,   KBr  0.60-2.00 (9H,m), 2.26 (3H,s),                            &#34;       20 4 4 11627,        2.41 (3H,s), 3.26 (2H,t),                                   100 4 4 11657         5.19 (2H,s), 6.41 (1H,s),             6.70-8.05(9H,m), 12.54 (1H,br)94   1630,   Neat                        20 1 4 11670                               100 1 4 195   1633,   KBr  1.37 (3H,t), 2.26 (3H,s),                            CDCl.sub.3                                    20 4 4 11675         3.22 (2H,q), 5.13 (2H,s),                                   100 4 4 2             6.44 (1H,s), 6.70-8.43 (9H,m),             13.22 (1H,br)96                1.00 (3H,t), 1.77 (2H,m),                            CDCl.sub.3                                    20 4 4 1             2.26 (3H,s), 3.20 (2H,t),                                   100 4 4 1             5.20 (2H,s), 6.43 (1H,s),             6.70-8.33 (9H,m), 13.18 (1H,br)97   1637,   KBr  0.70-2.00 (7H,m), 2.26 (3H,s),                            &#34;       20 4 4 11680         3.18 (2H,t), 5.16 (2H,s),                                   100 4 4 1             6.39 (1H,s), 6.70-8.40 (9H,m),             13.18 (1H,br)98   1605,   KBr                         20 4 4 11630,                              100 4 4 3167399   1630,   Neat 2.25 (3H,s), 3.41 (3H,s),                            CDCl.sub.3                                    20 4 4 11670         5.01 (2H,s), 5.45 (2H,s),                                   100 4 4 1             6.50 (1H,s), 6.70-7.77 (10H,m),             12.45(1H,br)100               2.05 (3H,s), 2.30 (3H,s),                            &#34;       20 3 4 1             4.83 (2H,d), 6.31 (1H,s),                                   100 3 4 1             6.60-7.60 (14H,m), 12.50 (1H,br)101  1600,   KBr  2.16 (3H,s), 2.25 (3H,s),                            CDCl.sub.3                                    20 4 4 11623,        4.79 (2H,d), 6.53 (1H,s),                                   100 4 4 11670         6.50-7.60 (14H,m),             12.40 (1H,br)102  1627,   KBr  2.32 (3H,s), 4.66 (1H,d),                            &#34;       20 4 4 11677         5.05 (1H,d), 6.63 (1H,s),                                   100 4 4 1             6.60-7.60 (14H,m),             12.67 (1H,br)103  1625,   Neat                        20 4 4 11680                               100 4 4 3104  1630,   KBr  0.80-2.00 (7H,m), 1.18 (6H,t),                            CDCl.sub.3                                    20 5 5 51657,        2.36 (3H,s), 2.65 (4H,q),                                   100 5 5 51637         3.38 (2H,t), 3.60 (3H,s),             6.42 (1H,s), 7.08 (3H,s),             11.80 (1H,br)105  1667    KBr                         20 4 5 5                                   100 4 5 5106  1620,   KBr  0.70-2.00 (7H,m), 1.18 (6H,t),                            CDCl.sub. 3                                    20 4 5 51655         2.17 (3H,s), 2.30 (3H,s),                                   100 5 5 5             2.67 (4H,q), 3.40 (2H,t),             3.61 (3H,s), 7.08 (3H,s),             11.85 (1H,br)107  1640,   KBr  0.70-2.00 (7H,m), 1.16 (6H,t),                            &#34;       20 5 5 51667         2.36 (3H,s), 2.61 (4H,q),                                   100 5 5 5             3.34 (2H,t), 3.57 (3H,s),             6.38 (1H,s), 7.16 (2H,s),             11.99 (1H,br)108  1625,   KBr  0.70-2.00 (7H,m), 1.18 (6H,t),                            &#34;       20 5 5 51660         2.36 (3H,s), 2.62 (4H,q),                                   100 5 5 5             3.35 (2H,t), 3.57 (3H,s),             7.16 (2H,s), 11.75 (1H,br)109               0.70-2.00 (7H,m), 1.16 (6H,t),                            &#34;       20 5 5 5             2.16 (3H,s), 2.40 (3H,s),                                   100 5 5 5             2.63 (4H,q), 3.33 (2H,t)             3.61 (3H,s), 7.16 (2H,s),             12.07 (1H,br)110  1620,   KBr  1.03 (3H,t), 1.20 (6H,t),                            &#34;       20 5 5 51650         1.73 (2H,m), 2.17 (3H,s),                                   100 5 5 5             2.40 (3H,s), 2.63 (4H,q),             3.27 (2H,t), 3.62 (3H,s),             7.11 (3H,s), 11.83 (1H,br)111  1625,   KBr  1.17 (6H,t), 0.70-2.00 (5H,m),                            CDCl.sub.3                                    20 5 5 51655         2.16 (3H,s), 2.40 (3H,s),                                   100 5 5 5             2.62 (4H,q), 3.31 (2H,t),             3.61 (3H,s), 7.19 (2H,s),             12.04 (1H,br)112  1620,   KBr  0.70-2.00 (9H,m), 1.18 (6H,t),                            &#34;       20 4 4 41657         2.17 (3H,s), 2.30 (3H,s),                                   100 5 4 4             2.67 (4H,a), 3.40 (2H,t),             3.61 (3H,s), 7.00 (3H,s),             11.85 (1H,br)113  1630,   KBr  0.60-1.90 (7H,m), 1.89 (3H,s),                            &#34;       20 4 4 11677         4.01 (2H,t), 6.41 (1H,s),                                   100 4 4 1             6.90-7.70 (9H,m), 12.73 (1H,br)114  1600,   KBr                         20 4 4 11637,                              100 4 5 11667115  1635,   KBr  0.50-1.90 (7H,m), 1.78 (3H,s),                            CDCl.sub.3                                    20 3 5 11687         2.95 (2H,t), 6.44 (1H,s),                                   100 4 5 1             7.00-8.10 (8H,m), 12.60 (1H,br)116  1600,   KBr  0.40-2.10 (7H,m), 1.81 (3H,s),                            CDCl.sub.3                                    20 4 4 11635,        2.89 (2H,t), 6.41 (1H,s),                                   100 4 4 11680         6.80-8.00 (9H,m), 12.78 (1H,br)117  1603,   KBr  0.40-2.00 (7H,m), 1.78 (3H,s),                            &#34;       20 4 3 11640,        .234 (3H,s), 3.00 (2H,t),                                   100 4 3 11670         6.35 (1H,s), 6.70-7.90 (9H,m),             13.11 (1H,br)118  1600,   KBr  0.35-2.00 (7H,m), 1.87 (3H,s),                            &#34;       20 1 4 11635,        3.00 (2H,t), 6.37 (1H,s),                                   100 1 4 11675         6.70-8.00 (9H,m), 12.90 (1H,br)119  1600,   KBr  0.40-2.00 (7H,m), 1.85 (3H,s),                            &#34;       20 4 4 11640,        3.03 (2H,t), 6.38 (1H,s),                                   100 4 4 11685         6.75-7.80 (9H,m), 12.82 (1H,br)120  1605,   KBr  0.40-2.20 (7H,m), 1.24 (3H,t),                            &#34;       20 4 4 11640,        1.84 (3H,s), 2.69 (2H,q),                                   100 4 4 11675         3.05 (2H,t), 6.39 (1H,s),             6.70-7.85 (9H,m), 13.07 (1H,br)121  1600,   KBr  0.50-2.00 (7H,m), 1.88 (3H,s),                            CDCl.sub.3                                    20 1 4 11637,        3.00 (2H,t), 6.37 (1H,s),                                   100 1 4 11695         6.75-7.80 (8H,m), 12.72 (1H,br)122  1600,   KBr  0.40-2.00 (7H,m), 1.91 (3H,s),                            &#34;       20 4 4 11633,        3.08 (2H,t), 3.82 (3H,s),                                   100 4 4 11673         6.42 (1H,s), 6.60-7.80 (9H,m),             12.90 (1H,br)123  1603,   KBr  0.40-2.00 (7H,m), 2.00-2.70 (1H,                            &#34;       20 4 4 11640,        m), 1.85 (3H,s), 3.10-3.90                                   100 4 4 11675         (1H,m), 6.46 (1H,s), 6.80-7.85             (8H,m), 12.73 (1H,br)124  1600,   KBr  0.50-2.00 (7H,m), 1.85 (3H,s),                            &#34;       20 4 4 11635,        3.00 (2H,t), 6.36 (1H,s),                                   100 4 4 11680         6.70-7.80 (8H,m), 12.75 (1H,br)125  1610,   KBr  0.50-1.80 (7H,m), 1.87 (3H,s),                            &#34;       20 4 4 11640,        2.29 (6H,s), 3.03 (2H,t),                                   100 4 4 21673         6.43 (1H,s), 6.40-7.83 (7H,m),             12.40 (1H,br)126  1637,   KBr  0.50-1.90 (7H,m), 1.20 (6H,t),                            CDCl.sub.3                                    20 1 4 11660         1.89 (3H,s), 2.70 (4H,q),                                   100 1 4 1             3.05 (2H,t), 6.45 (1H,s),             7.00-7.55 (7H,m), 12.00 (1H,br)127  1633,   KBr  1.12 (6H,t), 2.03 (3H,s),                            &#34;       20 4 4 11663         2.54 (4H,q), 6.61 (1H,s),                                   100 4 4 1             6.60-7.50 (12H,m),             11.00 (1H,br)128               0.50-1.93 (7H,m), 1.16 (6H,t),                            &#34;       20 1 4 5             2.10 (3H,s), 2.62 (4H,q),                                   100 4 4 5             2.90-3.35 (2H,m), 6.23 (1H,s),             7.06 (3H,s), 11.44 (1H,br),             12.23 (1H,s)129  1653,   KBr  2.31 (3H,s), 6.23 (1H,s),                            CDCl.sub.3                                    20 1 1 11683         6.80-7.70 (9H,m),                            -DMSO-d.sup.6                                   100 1 1 1             10.90-12.00 (1H,br),             12.53 (1H,br)130  1633,   KBr  1.03 (3H,t), 1.19 (6H,t),                            CDCl.sub.3                                    20 5 5 51637         1.67 (2H,six), 2.30 (3H,s),                                   100 5 5 5             2.66 (4H,q), 3.30 (2H,t),             3.49 (3H,s), 6.33 (1H,s),             7.05 (3H,s), 11.90 (1H,br)131  1637,   KBr  1.03 (3H,t), 1.16 (6H,t),                            CDCl.sub.3                                    20 5 5 51663         1.67 (2H,six), 2.32 (3H,s),                                   100 5 5 5             2.62 (4H,q), 3.30 (2H,t),             3.53 (3H,s), 6.35 (1H,s),             7.16 (2H,s), 12.05 (1H,br)132               1.01 (3H,t), 1.16 (6H,t),                            &#34;       20 5 5 5             1.70 (2H,six), 2.34 (3H,s),                                   100 5 5 5             2.57 (4H,q), 3.30 (2H,t),             3.57 (3H,s), 6.38 (1H,s),             7.35 (2H,s), 12.00 (1H,br)133               1.04 (3H,t), 1.18 (6H,t), 1.70                            &#34;       20 5 5 5             (2H,six), 2.36 (3H,s), 2.63                                   100 5 5 5             (4H,q), 3.32 (2H,t), 3.58 (3H,s),             3.77 (3H,s), 6.40 (1H,s),             6.64 (2H,s), 11.47 (1H,br)134               1.18 (6H,t), 1.22 (3H,t),                            &#34;       20 4 5 5             0.80-2.10 (5H,m), 2.35 (3H,s),                                   100 5 5 5             2.62 (6H,q), 3.32 (2H,t),             3.56 (3H,s), 6.37 (1H,s),             6.87 (2H,s), 11.60 (1H,br)135  1600,   KBr  2.32 (3H,s), 3.11 (3H,s),                            &#34;       20 1 3 21633,        6.47 (1H,s), 6.70-7.70 (9H,m),                                   100 1 3 51675         12.75 (1H,br)136  1633,   KBr  1.18 (6H,t), 1.38 (3H,t),                            CDCl.sub.3                                    20 5 5 51667         0.70-2.00 (7h,m), 2.40 (3H,s),                                   100 5 5 5             2.64 (4H,q), 3.10-3.70 (2H,m),             4.02 (2H,q), 6.41 (1H,s),             7.20 (2H,s), 12.08 (1H,br)137          KBr  1.16 (6H,t), 0.45-2.00 (7H,m),                            &#34;       20 1 3 51657         2.44 (3H,s), 2.63 (4H,q),                                   100 1 5 5             2.80-3.40 (2H,m), 7.09 (3H,s),             11.75 (2H,br)138  1613,   KBr  1.03 (3H,t), 1.18 (6H,t),                            &#34;       20 5 5 51660         1.70 (2H,six), 2.70 (3H,s),                                   100 5 5 5             2.68 (4H,q), 3.28 (2H,t),             3.68 (3H,s), 7.11 (3H,s),             11.07 (1H,br)139  1610,   KBr  1.03 (3H,t), 1.16 (6H,t),                            &#34;       20 5 5 51660         1.70 (2H,six), 2.62 (4H,q),                                   100 5 5 5             2.69 (3H,s), 3.27 (2H,t),             3.67 (3H,s), 7.17 (2H,s),             11.27 (1H,br)140  1600,   KBr  1.03 (3H,t), 1.18 (6H,t), 1.23                            &#34;       20 4 5 51667         (3H,t), 1.70 (2H,six), 2.61                                   100 5 5 5             (2H,q), 2.66 (4H,q), 2.68 (3H,s),             3.27 (2H,t), 3.67 (3H,s),             6.93 (2H,s), 10.86 (1H,br)141  1607,   KBr  1.17 (6H,t), 1.43 (3H,t),                            CDCl.sub.3                                    20 5 5 51663         0.60-2.00 (7H,m), 2.63 (4H,q),                                   100 5 5 5             2.75 (3H,s), 3.00-3.60 (2H,m),             4.14 (2H,q), 7.19 (2H,s),             11.35 (1H,br)142               1.03 (3H,t), 1.18 (6H,t),                            &#34;       20 4 5 5             1.23 (3H,t), 1.70 (2H,six),                                   100 5 5 5             2.17 (3H,s), 2.40 (3H,s),             2.60 (2H,q), 2.65 (4H,q),             3.32 (2H,t), 3.61 (3H,s),             6.91 (2H,s), 11.62 (1H,br)143  1620,   KBr  1.03 (3H,t), 1.16 (6H,t),                            &#34;       20 4 5 51660         1.70 (2H,six), 2.16 (3H,s),                                   100 4 5 5             2.40 (3H,s), 2.60 (4H,q),             3.32 (2H,t), 3.62 (3H,s),             7.38 (2H,s), 12.05 (1H,br)144  1617,   KBr  1.17 (6H,t), 1.23 (3H,t),                            &#34;       20 5 5 51650         0.70-2.20 (7H,m), 2.39 (3H,s),                                   100 5 5 5             2.63 (4H,q), 2.67 (2H,q),             3.33 (2H,t), 3.61 (3H,s),             7.20 (2H,s), 12.16 (1H,br)145  1633,   Neat 1.03 (3H,t), 1.19 (6H,t),                            &#34;       20 3 5 51663         1.28 (3H,t), 1.70 (2H,six),                                   100 4 5 5             2.67 (6H,q), 3.40 (2H,t),             3.59 (3H,s), 6.46 (1H,s),             7.10 (3H,s), 11.82 (1H,br)146  1617,   KBr  1.18 (6H,t), 1.25 (3H,t),                            CDCl.sub.3                                    20 3 4 51667         0.70-2.00 (7H,m), 2.17 (3H,s)                                   100 4 5 5             2.65 (4H,q), 2.81 (2H,q),             3.10-3.60 (2H,m), 3.67 (3H,s),             7.19 (2H,s), 12.08 (1H,br)147  1625,   KBr  0.40-1.20 (7H,m), 1.83 (3H,s),                            &#34;       20 4 4 11690         3.02 (2H,t), 6.41 (1H,s),                                   100 4 4 1             6.80-7.90 (10H,m),             13.02 (1H,br)148  1633,   KBr  0.35-2.00 (7H,m), 1.73 (3H,s),                            &#34;       20 4 4 11677         1.93 (3H,s), 2.00-2.50 (1H,m),                                   100 4 4 1             3.25-3.95 (1H,m), 6.43 (1H,s),             6.70-7.85 (9H,m), 13.13 (1H,br)149  1603,   KBr  0.40-2.00 (7H,m), 1.84 (3H,s),                            &#34;       20 4 4 11640,        2.00-3.90 (2H,m), 6.40 (1H,s),                                   100 4 4 11673         6.80-8.00 (9H,m), 12.87 (1H,br)150               1.10 (6H,t), 2.24 (3H,s),                            &#34;       20 4 5 5             2.41 (3H,s), 2.51 (4H,q),                                   100 5 5 5             3.23 (3H,s), 6.85-7.55 (8H,m),             11.23 (1H,br)151  1633,   KBr  0.40-2.00 (7H,m), 1.81 (3H,s),                            CDCl.sub.3                                    20 4 4 11680,        2.97 (2H,t), 6.43 (1H,s),                                   100 4 4 12280         6.80-8.00 (9H,m), 12.63 (1H,br)152  1600,   KBr  0.40-2.00 (7H,m), 1.87 (3H,s),                            CDCl.sub.3                                    20 4 3 11637,        2.97 (2H,t), 6.44 (1H,s),                            -DMSO-d.sup.6                                   100 4 4 11680         6.80-8.70 (9H,m), 12.60 (1H,br)153  1633,   KBr  0.40-2.00 (7H,m), 1.82 (3H,s),                            CDCl.sub.3                                    20 1 4 11685         3.01 (2H,t), 6.37 (1H,s),                                   100 1 4 1             6.80-7.85 (9H,m), 12.82 (1H,br)154  1600,   KBr  0.40-2.00 (7H,m), 1.86 (3H,s),                            CDCl.sub.3                                    20 4 4 11633,        2.41 (3H,s), 2.83 (2H,t),                            -DMSO-d.sup.6                                   100 4 4 11675         6.33 (1H,s), 6.80-8.00 (9H,m),             12.56 (1H,br)155  1600,   KBr  0.40-2.00 (7H,m), 1.80 (3H,s),                            CDCl.sub.3                                    20 4 4 11637,        2.05 (3H,s), 2.00-2.60 (1H,m),                                   100 4 4 11673         3.25-3.90 (1H,m), 6.46 (1H,s),             6.80-7.80 (8H,m)             12.90 (1H,br)156               0.40-2.00 (7H,m), 1.86 (3H,s),                            CDCl.sub.3                                    20 4 4 1             2.45 (3H,s), 3.03 (2H,t),                                   100 4 4 1             6.40 (1H,s), 6.80-7.85 (8H,s),             12.85 (1H,br)157               0.30-2.50 (7H,m), 1.81 (3H,s),                            &#34;       20 4 3 1             1.98 (3H,s), 1.90-2.50 (1H,m),                                   100 4 3 1             3.20-4.10 (1H,m), 6.49 (1H,s),             6.75-7.90 (8H,m), 12.87 (1H,s)158               0.40-2.00 (7H,m), 1.79 (3H,s),                            &#34;       20 1 4 1             2.50-3.40 (2H,m), 6.42 (1H,s),                                   100 4 4 1             6.80-8.90 (9H,m),             12.70 (1H,s),159  1613,   KBr  0.40-2.00 (7H,m), 1.88 (3H,s),                            &#34;       20 4 4 11637,        2.31 (6H,s), 3.03 (2H,t),                                   100 4 4 11683         6.42 (1H,s), 6.75-7.90 (7H,m),             12.41 (1H,br)160  1605,   KBr  0.40-2.00 (7H,m), 1.88 (3H,s),                            &#34;       20 4 4 11637,        2.29 (6H,s), 2.41 (3H,s),                                   100 4 4 21673         3.05 (2H,t), 6.42 (1H,s),             6.70-7.90 (7H,m), 12.56 (1H,br)161  1613,   KBr  0.40-2.00 (7H,m), 1.86 (3H,s),                            CDCl.sub.3                                    20 4 4 11640,        2.30 (6H,s), 2.50-3.50 (2H,m),                                   100 4 4 21680         6.44 (1H,s), 6.70-8.00 (7H,m),             12.38 (1H,br)162  1635,   KBr  0.40-2.00 (7H,m), 1.22 (6H,t),                            &#34;       20 3 4 21667         1.91 (3H,s), 2.69 (4H,q),                                   100 4 4 2             2.50-3.50 (2H,m), 6.47 (1H,s),             6.80-8.00 (7H,m), 11.93 (1H,br)163  1633,   KBr  0.40-2.00 (7H,m), 1.19 (3H,s),                            &#34;       20 1 2 11655         1.87 (3H,s), 2.65 (4H,q),                                   100 4 5 3             2.20-4.10 (2H,m), 6.47 (1H,s),             6.80-7.90 (7H,m), 11.85 (1H,br)164               1.03 (3H,t), 1.16 (6H,t),                            &#34;       20 5 5 5             1.29 (3H,t), 1.70 (2H,six),                                   100 5 5 5             2.63 (4H,q), 3.07 (2H,q),             3.27 (2H,t), 3.72 (3H,s),             7.06 (3H,s), 10.95 (1H,br)165               1.04 (3H,t), 1.18 (6H,t),                            &#34;       20 5 5 5             1.70 (2H,six), 2.64 (4H,q)                                   100 5 5 5             2.76 (3H,s), 3.34 (2H,t),             3.68 (3H,s), 3.77 (3H,s),             6.64 (2H,s), 10.64 (1H,br)166               1.01 (3H,t), 1.18 (6H,t),                            CDCl.sub.3                                    20 5 5 5             1.70 (2H,six), 2.74 (3H,s),                                   100 5 5 5             2.61 (4H,q), 3.32 (2H,t),             3.76 (3H,s), 7.39 (2H,s),             11.13 (1H,br)__________________________________________________________________________ X: Oryza sativa L. Y: Echinochloa crusgalli L. Z: Raphanus sativus L.