Abstract:
The invention relates to a dermo-cosmetic composition for pets. This composition includes a diffusion solvent vehicle that enables, by a simple application to one or more points of the cutaneous surface, a diffusion over the entirety thereof and at the level of the sebaceous glands. The active ingredients, primarily include a complex of essential oils and poly-unsaturated fatty acids, stored in the sebaceous glands, can be salted out progressively with the sebum product to the surface of the skin.

Description:
RELATED U.S. APPLICATIONS 
       [0001]    Not applicable. 
       STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT 
       [0002]    Not applicable. 
       REFERENCE TO MICROFICHE APPENDIX 
       [0003]    Not applicable. 
       FIELD OF THE INVENTION 
       [0004]    This invention concerns a dermo-cosmetic composition for pets (including new “NAC” pets). 
       BACKGROUND OF THE INVENTION 
       [0005]    Veterinary dermatology products for animal preventive or maintenance usage are generally designed in the form of creams, lotions or shampoos. 
         [0006]    Their application to animals is always delicate and sometimes unpleasant for them. 
         [0007]    The user&#39;s normal trend is often to overdose the quantity of product applied as it is frequently the case for lotions and powders, which causes some disturbance in the animal. 
         [0008]    Powders, shampoos or lotions often have a localized effect, which does not make it possible to cover in one single application all needs for a dermo-cosmetic treatment:
       skin care and hydration;   soothing effect;   deodorant effect;   sanitizing &amp; purifying effect;   antioxidant and anti-radical effect; and   insect repellent effect.       
 
         [0015]    The purpose of this invention is to eliminate these disadvantages by achieving a composition easier to apply and that in its most elaborate formulation can meet many basic needs of an animal dermo-cosmetic treatment. 
         [0016]    The composition under the invention makes it possible after a localized application to diffuse the active ingredients over the whole surface through the diffusion carrier solvent. Then the invention uses the capacity of the sebaceous glands to store in certain conditions the treatment active ingredients and to gradually release them through the natural production of sebum. 
         [0017]    To that effect, the dermo-cosmetic composition under the invention, using the capacity of the sebaceous glands to store the active ingredient(s) and to diffuse them through the sebum, is characterized mainly in that it comprises at least:
       a carrier that is a solvent, and   a complex of essential oils is selected by themselves or in combination based on the effects to be achieved.       
 
         [0020]    This combination makes it possible to propose a composition ready for use made mainly of a carrier that is a solvent and of essential oils that, once applied in one or more locations of the animal coat, achieves treatment over the whole skin surface of the animal for several days. Tests performed showed that a result was achieved within 7 days minimum. 
         [0021]    According to another characteristic of the invention, the solvent making up the carrier is an ethoxydiglycol. 
         [0022]    According to another characteristic, the composition comprises:
       a carrier consisting of an organic solvent,   a complex of essential oils, and   polyunsaturated fatty acids used locally in animals.       
 
         [0026]    According to a further characteristic of the invention, the above-described composition can contain a soothing agent and/or an anti-inflammatory and/or anti-pruriginous agent. 
         [0027]    Other advantages and characteristics of the invention will become obvious when reading the description below. 
         [0028]    The purpose of the composition under the invention is to achieve a treatment of animal skin that has several effects:
       prevention and hydration;   soothing effect;   deodorant effect;   sanitizing and purifying effect;   antioxidant and anti-radical effect; and   insect-repellent effect.       
 
         [0035]    The advantage of the invention is to be able to combine all or part of the above effects based on the complexity of the composition from an application over a limited area of the animal skin. 
       BRIEF SUMMARY OF THE INVENTION 
       [0036]    The invention is based on the association of a unique and innovating aromatic synergy with other skin hydrating, soothing, antioxidant and nurturing ingredients. Each essential oil that is part of the composition is subject to a precise qualitative definition based on EOBBD (Essential Oil Botanically and Biochemically Defined, ISO 9002 Certified Quality Assurance Process) criteria. 
         [0037]    One single application is sufficient for a small size animal. Two will be necessary for a larger size animal. 
         [0038]    According to a basic formulation, the composition under the invention comprises at least one carrier that is made of an organic solvent or equivalent and of a concentrated complex of at least two essential oils. 
         [0039]    The presence of the carrier allows for the application of the composition in one or two locations of the skin surface, the diffusion of the product, its storage through the sebaceous glands and its gradual release. 
         [0040]    To date, the capacity of the carrier had been used only to provide the animal with an insecticide product. The advantage of the invention is to propose a complete treatment of the skin and coat that has a sanitizing, appeasing and soothing effect on the animal:
       Through restoration of a balanced cutaneous ecosystem, and   The invention makes it possible to prevent inflammatory and infectious disorders of the epiderm and the appeasing and soothing effect of the composition provides the animal with a feeling of well-being and freshness that is a mood stabilizer.       
 
         [0043]    The originality of the composition makes it possible to bathe the animal 48 hours before or after the treatment, while still benefitting from the efficiency of the composition applied for one week minimum. 
     
    
     DETAILED DESCRIPTION OF THE INVENTION 
       [0044]    The organic solvent making up the carrier is preferably an intermediate polarity solvent, for example:
       an ethoxydiglycol or butylenes glycol, or propylene glycol, or glycerin in a proportion from 1% to 99% of the total composition in relation to its other components.       
 
         [0046]    More generally, the carrier is chosen from the following group:
       Acetone, acetonitrile, benzyl alcohol, butyldiglycol, dimethyl acetamide, dimethyl formamide, dipropylene glycol monobutyl ether, ethanol, isopropanol, methanol, ethylene glycol monoethyl ether, monoethyl acetamide, dipropylene glycol monomethyl ether, liquid polyoxyethylene-glycol, propylene glycol, 2-pyrrolidone, including N-methylpyrrolidone, diethyelene glycol monoethyl ether, ethylene glycol, diethyl phtalate, and a mixture of at least two of them.       
 
         [0048]    The above composition can be supplemented by polyunsaturated essential fatty acids to improve the skin surface. 
         [0049]    Polyunsaturated fatty acids omega 3 and omega 6 can be introduced by adding hemp seed oil (cannabis sativa) in a proportion that can range from 1% to 15% of the total composition or through natural substitutes such as:
       fish oil (orange roughy),   borage oil ( Borago Officinalis ),   coconut oil ( Cocos Nucifera ),   kukui oil,   sesame oil ( Sesamum indium ),   reconstituted synthetic AGPI&#39;s or natural extracts,   Eicopentaenoic acid (EPA) and docosahexaenoic acid (DHA),   shea butter,   olive oil ( Olea Europea ),   canola oil,   walnut oil,   soybean oil, and   anchusa oil ( Echium Plantagineum ),
 
that can be added to the composition in the proportion of 1 to 99%, more specifically 2% to 50% and preferably 5% to 10% of the total composition.
       
 
         [0063]    The composition can also contain a soothing and/or anti-inflammatory and/or anti-pruriginous agent. 
         [0064]    Preferably, the soothing agent is laureth 9 in the proportion of 0.8% to 3% or its substitutes, such as:
       menthol, and its salts, procaine, lidocaine, corticoids, by themselves or in combination of at least two of them.       
 
         [0066]    The laureth 9 polymer is a mixture of polyethylene glycol monolauric ethers with an average of 9 ethylene oxide groups per molecule. 
         [0067]    The anti-inflammatory agent can be bisabolol in the proportion of 1% to 5% or its substitutes:
       natural or synthetic azulene,   allantoin,   glycyrrhetinic 18 beta acid and its salts in the proportion of 0.01% to 10%, and preferably from 0.01 to 1%, and   aloe extracts,     calendula  extracts,   carrot extracts,
 
in the proportion of 0.01 to 10%, and preferably from 5 to 10%.
       
 
         [0074]    Bisabolol also called alpha-bisabolol has the following formulation:
   1-methyl-4(1,5-dimethyl-1 hydroxyhex-4(5)-enyl)-cyclohexen-1;   6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2 ol.   
 
         [0077]    The above composition contains an antioxidant and anti-radical product: tocopherol or vitamin E, in the form of tocopheryl acetate in the proportion of 0.2% to 2% or its substitutes, such as tocopheryl palmitate or tocopheryl linoleate. 
         [0078]    The composition also contains in combination with any one of the above compounds a thickening or stabilizing crystallization-inhibiting film-forming agent, such as polyvinyl pyrrolidone or a product chosen from the following group:
       hydroxymethyl cellulose, polyvinyl alcohols, vinyl acetate and vinyl pyrrolidone copolymers, polyethylene glycols, benzyl alcohol, mannitol, glycerol, sorbitol, polyoxyethylene sorbitan esters, lecithin, sodium carboxymethyl cellulose, acrylic derivatives such as methacrylates derived from polyesters of the trimethyl pentanediol/adipic acid type and others.       
 
         [0080]    The composition also contains an insect-repellent product, such as neem seed oil that is in fact  Azadirachta  indica at 0.25% of azadirachtin or its substitutes such as:
       castor oil ( Ricinus Communis ),   diethyl toluamide and butyl acetylaminopropionate,   dimethyl phtalate,   ethyl hexanediol,   natural and synthetic camphor,   pyrethrum and derivatives ( Pyrethum Album ), and   oil garlic ( Allium Sativum ).       
 
         [0088]    More generally, the composition under the invention can contain the following essential oils by themselves or in combination:
         Rosmarinus officinalis  in the proportion of 0.3% to 0.9% with a purifying and soothing sanitizing effect or eucalyptol.     Lavandula hybrida  in the proportion of 0.3% to 0.9% or  lavandula angustifolia  with a deodorant effect.     Eugenia caryophyllus  with an insect-repellent effect, in the proportion of 0.3% to 0.9%.     Melaleuca Alternifolia  or  origan majorana  in the proportion of 0.3% to 0.9% with an anti-infectious effect.     Cinnamorum Camphora  or camphor, in the proportion of 0.15% to 0.6% with a deodorant and anti-pruriginous effect.     Mentha Piperita  or  mentha orvensis  in the proportion of 0.15% to 0.6% with a deodorant effect.     Cedrus atlantica  or SAS libanus, in the proportion of 0.15% to 0.6% with an anti-parasitic, cicatrizant and anti-carcinogen effect.     Curcuma longa  or  curcuma zedoaria  in the proportion of 0.15% to 0.6% that also has an anti-parasitic effect.     Origanum compactum  or  origonum vulgare , in the proportion of 0.06% to 0.3% with an insect-repellent and antimicrobial effect.     Gaultheria procumbens  or its methyl salicylate substitute with a sedative and anti-pruriginous effect.   Synthetic musk or musk ketone, in the proportion of 0.06% to 0.3% to perfume or mask natural odors.       
 
         [0100]    The above compounds are used in combination in the composition under the invention based on the effects sought. 
         [0101]    More generally, the essential oils in the attached list can be combined in the composition under the invention. 
         [0000]    
       
         
               
             
               
               
               
               
               
             
               
               
               
               
             
           
               
                   
               
               
                 ESSENTIAL OIL COMPLEX SUBSTITUTES 
               
               
                   
               
             
             
               
                   
               
             
          
           
               
                 Ajowan 
                 Almond Tree, 
                 Ammi, Khella 
                 Odorant Dill Seed 
                 Angelica 
               
               
                   
                 Bitter 
               
               
                 White Armose 
                 Basilic 
                 Bay 
                 Bergamot 
                 Rosewood 
               
               
                 Herb 
               
               
                 Sandlewood 
                 Boldo 
                 Bucchu 
                 Cabreuva 
                 Cajeput 
               
               
                 Calamus 
                 Chamomile, 
                 Camphor 
                 Cinnamon, Ceylon 
                 Cinnamon, China 
               
               
                   
                 Roman or 
               
               
                   
                 Noble 
               
               
                 Cardamones 
                 Carrot 
                 Carvi 
                 Catmin 
                 Cedarwood, Atlas 
               
               
                 Cedarwood, 
                 Celeri 
                 Chenopodium 
                 Rockrose, 
                 Yellow Lemon 
               
               
                 Virginia 
                   
                 Vermifuge. 
                 Labdanum-Bearing 
               
               
                 Citronnella, 
                 Citronnella, Java 
                 Copahu 
                 Coriander 
                 Cubeb 
               
               
                 Ceylon 
               
               
                 Cumin 
                 Curcuma 
                 Evergreen Cypress 
                 Douglas 
                 Elemi 
               
               
                 Incense 
                 Black Spruce 
                 Tarragon 
                 Eucalyptus 
                 Lignum Vitae 
               
               
                 Galbanum 
                 Gaultheria, 
                 Juniper 
                 Geranium, 
                 Ginger 
               
               
                   
                 Wintergreen 
                   
                 Odorant 
               
               
                 Clove Tree 
                 Helichrysum 
                 Hyssop with lying 
                 Hyssopus 
                 Inula 
               
               
                   
                   
                 down branches 
                 Officinalis 
               
               
                   
               
             
          
           
               
                 Iormenie, Wild 
                 Lantana 
                 Laurus Nobilis 
                 Spike Lavender 
               
               
                 Chamomile 
               
               
                 Lavandula Officinalis 
                 Stoechas Lavender 
                 Lavandula Hybrida 
                 Lemongrass 
               
               
                 Pistacia Lentiscus 
                 Lepstospermum 
                 Sweet Lime 
                 Litsea 
               
               
                 Lovage 
                 Red Mandarin 
                 Sweet Marjoram 
                 Majorana Sylvestris 
               
               
                 Wild Marjoram 
                 Matricaria 
                 Larch 
                 Melissa Officinalis 
               
               
                 Wild Mint 
                 Peppermint 
                 Pennyroyal 
                 Yarrow 
               
               
                 St. Johns-wort 
                 Nutmeg 
                 Myrrh 
                 Myrtle 
               
               
                 Spikenard 
                 Niaouli 
                 Orange Tree 
                 Sweet Orange 
               
               
                 Origanum 
                 Spanish Origanum 
                 Origanum Vulgare 
                 Palmarosa 
               
               
                 Grapefruit 
                 Patchouli 
                 Parsley 
                 Landes Pine 
               
               
                 Pinus Syvestris 
                 Black Pepper 
                 Aromatic Vinyl 
                 Rosemarinus Officinalis 
               
               
                   
                   
                 Pyrrolidone 
               
               
                 Pyramidal Rosemary 
                 Bulgarian Rose 
                 Sandalwood Amyris 
                 Santolina 
               
               
                   
                   
                   
                 Dwarf Cypress 
               
               
                 Balsam Fir 
                 Siberian Fir 
                 Silver Fir 
                 Savory 
               
               
                 Sassafras 
                 Small Leaf Sage 
                 Salvia Officinalis 
                 Clary 
               
               
                 Wild Thyme 
                 Blue Tansy 
                 Tea tree 
                 Turpentine 
               
               
                 Thuya 
                 Thyme 
                 Savory Leaf Thyme 
                 Goldenrod 
               
               
                 Fleabane 
                 Lemon Verbena 
                 Vetiver 
                 Ylang-ylang, Full 
               
               
                   
                   
                   
                 Distillation 
               
               
                 Ylang-ylang, First 
               
               
                 Batch 
               
               
                   
               
             
          
         
       
     
         [0102]    The essential oils were selected based on precise specifications with regard to the active ingredients they contain. Among the active ingredients can be found in particular sesquiterpenes with anti-inflammatory properties, phenol compounds with locally immunostimulating and anti-infectious properties, other phenol compounds (eugenol et carvacrol) with insectifuge and repellent effects and esters with antalgesic and decongestant properties that may temper, even prevent, a possibly irritant action of the phenols on the skin. 
         [0103]    A formula especially suited for the composition under the invention contains:
       As carrier and skin solvent, an ethoxydiglycol.   As vegetal oil rich in polyunsaturated fatty acids, hemp oil (cannabis sativa).   As concentrated essential oils:
             Rosmarius Officinalis, Lavendula Hybrida,        Eugenia Caryophyllus, Melaleuca Alternifolia,        Cinnamomum Camphora, Mentha Piperita,        Cedrus Atlantica, Curcuma Longa, Origanum Compactum,        Gaultheria Procumbens , Musk.   
           As insect repellent and soothing product, neem seed extract ( azadirachta  Indica) at 0.25% of azadirachtin).   As soothing, desensitizing and anti-pruriginous ingredients, laureth 9.   As thickening, stabilizing crystallization-inhibiting agent forming a film on the animal skin, polyvinyl pyrrolidone as mentioned above in the description.   A vitamin E with antioxidant function, such as D alpha tocopherol or tocopheryl acetate, or the products mentioned above in the description, or the products mentioned above (other antioxidants): butyl hydroxyanisole, butyl hydroxytoluene, ascorbic acid, sodium metabisulfate, propyl gallate, sodium thiosulfate, mixture of no more than two of them.   An anti-inflammatory agent such as alpha-bisabolol, bisabolol or its substitutes as mentioned above in the description.       
 
         [0117]    The formulation active ingredients can be included in whole or in part in a “delay” formulation allowing for extended release time and thus extended action duration of these active ingredients. The compounds allowing for that modification can be chosen among beta-cyclodextrins, silica, cellulose fibers, nylon, poly-methacrylates. 
         [0118]    A delay or scheduled release formula can allow for extended release of the active ingredients up to twenty-eight days after application. The delay formulas use:
       Beta-cyclodextrins, cyclic natural sugars: present in the formulation with a concentration ranging from 2 to 10%.   And/or cellulose fibers from wood: present in the formulation with a concentration ranging from 2 to 10%.   And/or polymethyl methacrylate and nylon spheres: present in the formulation with a concentration ranging from 4 à 12%.   And/or coated or non-coated silica microreservoirs: present in the formulation with a concentration ranging from 2 to 10%.   And/or linear polyester polymers with a molecular weight of 800 through 5000 Daltons both occlusive and retentive: present in the formulation with a concentration ranging from 10 to 20%.       
 
         [0124]    The proportions of each component are taken in the above-mentioned percentage values, said values being expressed in percentages of the total and full composition.