Abstract:
An apparatus and method for predicting potentially fatal arrhythmias up to twenty four hours in advance of the event by employing formulas indicating either too little or too much heart rate variability. A number of these formulas have both predetermined upper and lower limits, which if exceeded for a period of time are a predictor of a potentially fatal arrhythmia. When a patient&#39;s ALARM condition is predicted, whether the patient is indoors or outdoors, conscious or unconscious, a redundant protocol is utilized to relay that ALARM condition to a central monitoring station. The central monitoring station informs the patient&#39;s doctor, and then uses what ever means are available to transport the patient to the nearest emergency room for treatment. An apparatus and method for pacing the heart in a natural way, once a potentially fatal arrhythmia has been predicted is also disclosed.

Description:
BACKGROUND OF THE INVENTION 
     1. Field of the Invention 
     The normal heart rate is slightly irregular. Generally, normal irregularity of the heart rate reflects the permanent adaptation of the human body to the environment. In this context the first sign of an impaired heart rate is either a persistent increase or a persistent decrease in the variability of the heart&#39;s rate. Sometimes the change in the heart rate alternates between increases and decreases in the variability of the heart&#39;s rhythm, and vice versa. Prolonged increases, or decreases, and combinations thereof, can lead to cardiac adverse events ranging from non-sustained ventricular tachycardia to cardiac arrest. 
     It is believed the variability of the heart rate is controlled by two branches of the autonomic nervous system; the sympathetic branch and the parasympathetic branch. The sympathetic branch increases the heart rate. Its prime function is to prepare the body for stress, the so-called “fight or flight response.” The parasympathetic branch decreases the heart rate as when eating or sleeping. 
     This invention relates to the detection of normal and abnormal heart rate variability and the induction of normal heart rate variability. More particularly, the invention relates to methods and apparatus for the detection of a patient&#39;s heart rate variability that we believe is indicative of a patient&#39;s sympathetic/parasympathetic stress balance, or distress imbalance. 
     The invention also relates to heart monitoring devices used by individuals monitored in hospital intensive care units; by patient&#39;s after discharge from a hospital intensive care unit; and by patients when exercising to let them know that their stress state is optimal for conditioning their bodies. 
     The invention further relates to control of a pacemaker or cardioverter defibrillator with a pacemaker so that when the patient&#39;s heart rate is abnormal and distressful, according to the invention, a pacemaker or cardioverter defibrillator with a pacemaker induces a heart rate with a pseudo-normal or patient recorded variability for each particular patient. 
     The invention still further relates to a pacemaker that induces pseudo-normal or patient recorded heart rate variability. 
     2. Background Description 
     In the Soviet Union, Rhythmography, that is the study of normal and abnormal variations in the heart, was utilized extensively to determine the condition of individuals and their stress state. This was particularly true of cosmonauts. It was determined, for example, that the heart rate variability of a conditioned athlete is much greater than that of person with coronary disease. That is, the histogram of heart rate variation of a well conditioned athlete exhibits a broad range of variability in the Time Intervals between heart beats and a low relative Amplitude of the Mode. That is the highest number of Time Intervals recorded in a series of Time Intervals. The histogram of a person with a coronary disease exhibits a narrow range of variability and a high relative Amplitude of the Mode, that is the peak of the histogram. 
     Boris Golosarsky, previously received two patents in the Soviet Union, namely SU-1683679 and SU-1769894. SU-1683679 is for an apparatus, which enables a physician to determine the arithmetic Mean, the Mode, the relative Amplitude of the Mode, and the range of variability of a subject. In the second patent in the Soviet Union, SU-1769894, he disclosed how these measurements may be utilized together with electrosleep to treat post myocardial infarction e.g., heart attack patients. 
     GW Scientific, Inc. measured a patient&#39;s heart rate variability in relation to the patient&#39;s baseline heart variability using mathematical constructs such as UV, AMo, and DX, all as described in U.S. Pat. No. 5,718,235, incorporated herein by reference in its entirety. 
     Polar Electro Oy of Finland has a patented apparatus comprised of a chest strap with a two lead ECG signal sensor and transmitter, which transmits the heart beat Time Intervals to a wrist mounted unit that can be conveniently used in this invention. See U.S. Pat. Nos. 4,625,733; Des. 278,746; and Des. 287,403, all incorporated herein by reference in their entirety. 
     Pulse sensors of various types may also be used to detect the Time Interval between heart beats, (Start-of-Systole to Start-of-Systole, SOS), is essentially equal to the Time Interval between RR peaks in an electrocardiogram, (ECG). 
     Additional background information is disclosed by Baevsky, R. M., Kirillow, O. I., Kleckin, C. Z., (1984),  Mathematical Analysis of Stress Changes in Heart Rhythm , Moscow, Academy of Science, USSR. 
     Schmidt et al, “Heart-rate Turbulence After Ventricular Premature Beats As a Predictor of Mortality After Acute Myocardial Infarction,” Lancet Apr. 24, 1999; 353 (9162):1390-6, relates to ACRRs. This article discloses a formula for predicting myocardial infarction 21 to 24 months in advance. In contrast, the present invention predicts up 24 hours in advance. The formula in this article is quite different from those employed in the present invention. 
     SUMMARY OF THE INVENTION 
     Definitions 
     TABLE A shows there are five abnormal predictive markers, which are comprised of two continuums, the Heart Rate Variability continuum and the Heart Rate continuum, as well as Erratic Variability. The Heart Rate Variability continuum has, as its extremes, high and low variability. The Heart Rate continuum has, as its extremes, bradycardia and tachycardia. Erratic Variability, is comprised of Premature Ventricular Contractions (PVCs) and Atrial Fibrillation (A-Fib). TABLE A lists the parameters in each continuum Values for these parameters are calculated by formulas and compared with values which are considered normal and values which are considered abnormal as explained in the specification. These parameters in TABLE A are also labeled by reference numerals and these reference numerals may be employed elsewhere in the specification when discussing the parameters. 
     
       
         
               
             
               
               
               
             
               
             
               
               
               
             
               
             
               
               
             
           
               
                 TABLE A 
               
               
                   
               
             
             
               
                 HEART RATE VARIABILITY CONTINUUM 
               
             
          
           
               
                 High Variability 
                 Normal 
                 Low Variability 
               
               
                 dispersion of heart beats 
                   
                 centrality of heart beats 
               
               
                 Absolute SPS(1) 
                 Normal 
                 Absolute SPS(2) 
               
               
                 Absolute AMo(3) 
                 Normal 
                 Absolute AMo(4) 
               
               
                 Absolute DX(5) 
                 Normal 
                 Absolute DX(6) 
               
               
                 Absolute DX/Median(7) 
                 Normal 
                 Absolute DX/Median(8) 
               
               
                   
                   
                 Low HRV(9) 
               
               
                   
                   
                 2.0 Caution &gt; 2.5 
               
               
                   
                   
                 ALARM(10) 
               
             
          
           
               
                 HEART RATE CONTINUUM 
               
             
          
           
               
                 bradycardia(11) 
                 Normal 
                 tachycardia(12) 
               
             
          
           
               
                 ERRATIC VARIABILITY 
               
             
          
           
               
                   
                 ACRR(13) 
               
               
                   
                 PVCs &amp; A-Fib 
               
               
                   
               
             
          
         
       
     
     Data sources: ECG (RR) Time Intervals or pulse wave Start-of-Systole to Start-of-Systole (SOS) Time Intervals from the hardware sources discussed elsewhere. (Note: RR and SOS Time Intervals are used interchangeably to indicate the Time Interval between heart beats. 60 seconds divided by the Time Interval in seconds equals beats per minute, bpm.) 
     Time Interval: A Time Interval is the duration of time between heart beats, or RR peaks, preferably measured to an accuracy of 20 milliseconds, 0.02 seconds. The accuracy of the Time Interval can range from 15 milliseconds to 30 milliseconds. 
     Time Segment: A Time Segment is a series of Time Intervals, which can vary in length from 51 Time Intervals to 301 Time Intervals. The preferred default setting is 101 Time Intervals. Typically, from this 101 Time Intervals, up to about 6 outliers are removed. 
     The time between each heart beat is designated an RR Time Interval. RR Time Intervals are then divided into three subsets as shown in TABLE B. 
     
       
         
               
             
               
               
               
             
           
               
                 TABLE B 
               
             
             
               
                   
               
               
                 RR Time Intervals (milliseconds) 
               
             
          
           
               
                 NN 
                 ACRR 
                 MARR 
               
               
                   
               
               
                 75 to 125 
                 1 to 74 and/or 126 to 169 
                 0 and/or 170+ 
               
               
                   
               
             
          
         
       
     
     (Normal-to-Normal): Normal-to-Normal means a normal Time Interval between an RR peak. NN Time Intervals are used to calculate twelve of the thirteen predictive markers. NN equals 75 to 125 milliseconds. 
     ACRR (Abnormal Cardiac RR): Abnormal Cardiac RR means when the present Time Interval differs from the previous Time interval by +25% or −25%, and this situation occurs 50 or more times while accumulating a Time Segment of 101 NN Time Intervals, then this Time Segment is an ACRR Time Segment. If this condition persists for 52 minutes, or longer, then this is either a +2.5 or −2.5 point ALARM, as influenced by the results of “Absolute SPS” through “2.0 Caution&gt;2.5 ALARM” formulas, the first 10 formulas, for the parameters as set forth below. ACRRs are comprised of Premature Ventricular Contractions (PVCs), and Atrial Fibrillation (A-Fib). ACRRs equal intervals of 1 to 74 milliseconds, and/or 126 to 169 milliseconds. 
     MARR (Motion Activated RR): Motion Activated RR means some sort of motion influenced the Time Interval between the RR peaks. MARRs equal intervals of Zero and/or 170+ milliseconds. 
     Outliers are typically the three shortest and the three longest Time Intervals in a 101 NN Time Interval, Time Segment, and are discarded after ACRRs are removed from the Time Segment, and before calculations are made of the other 12 predictive markers. 
     Non-Stationarity: If the Median and the Mode differ from each other in a 101 Time Interval Time Segment by 20% or more, than this is a case of non-stationarity and the values generated are discarded and not included in any calculations. 
     The following 10 formulas are for parameters all related to heart rate variability, HRV. The ALARM trigger points and the number of Time Segments the ALARM condition is present are for patients 55 years and older. 
     Absolute Sympathetic/Parasympathetic Stress (ABS.SPS): Sympathetic/Parasympathetic Stress is determined by the formula: 
     
       
         
           SPS={square root over ((0.5 /DX ) 2 +( AMo/ 10))} 
           2 
         
       
     
     In a Time Segment of 95 NN Time Intervals (101 NN Time Intervals minus 6 outliers), if SPS equals or exceeds 48 for any 25 Time Segments out of 50 Time Segments, then this is a +2.5 point ALARM. In a Time Segment of 95 NN Time Intervals, if SPS is between 47 and 3.0, then this is normal condition. In a Time Segment of 95 NN Time Intervals, if SPS equals or is less than 2.5 for any 25 Time Segments out of 50 Time Segments, then this is a −2.5 point ALARM (Parameters 1 and 2 of TABLE A). 
     Absolute AMo (ABS.AMo): Amplitude of the Mode is the largest number of identical Time Intervals occurring in the Mode of a Time Segment, (e.g. 70 for 70 Time Intervals out of 95 Time Intervals.) 
     In a Time Segment of 95 NN Time Intervals, if AMo, the most frequent heart rate, occurs 90 times or more for any 25 Time Segments out of 50 is a 2.5 point ALARM. In a Time Segment of 95 NN Time Intervals, if the average rate occurs between 11 through 94 times is Normal. In a Time Segment of 95 NN Time Intervals, if AMo the most frequent heart rate occurs 10 times or less for any 25 Time Segments out of 50, then this is a −2.5 point ALARM. (Parameters 3 and 4 of TABLE A). 
     Absolute DX (Delta X): Delta X is the difference between the longest value for a Time Interval in a Time Segment and the shortest value, after outliers, and ACRRs, if any, have been discarded (e.g. longest equals 0.72 seconds less shortest equals 0.64 seconds=0.08 seconds=Delta X). 
     In a Time Segment of 95 NN Time Intervals, if the difference, DX, between the longest and the shortest heart rate is 0.06 seconds or less for any 25 Time Segments out of 50 is a +2.5 ALARM. In a Time Segment of 95 NN Time Intervals, if the difference between the longest and the shortest heart rate is between 0.49 through 0.07 seconds is normal. In a Time Segment of 95 NN Time Intervals, if the difference, DX, between the longest and the shortest Time Interval is 0.50 seconds or more for any 25 Time Segments out of 50, then this is a −2.5 ALARM. (Parameters 5 and 6 of TABLE A). 
     Median (M): The Median is the Time Interval in a Time Segment, in which there are equal number Time Intervals equal to or larger than, and equal to or smaller than the Median Time Interval (e.g. the 47th Time Interval in a 95 Time Interval Time Segment). 
     Absolute DX/Median (ABS.DX/M): Delta X divided by the Median is a combination of the two markers above, DX and Median. 
     In a Time Segment of 95 NN Time Intervals, if DX/Median equals or is less than 0.02 for any 25 Time Segments out of 50 is a +2.5 point ALARM. In a Time Segment of 95 NN Time Intervals, if DX/Median is between 0.025 and 0.420 is normal in a Time Segment of 95 NN Time Intervals, if DX/Median equals or exceeds 0.425 for any 25 Time Segments out of 50, then this is a −2.5 point ALARM. (Parameters 7 and 8 of TABLE A). 
     Low Heart Rate Variability (Low-HRV): Low-HRV is a condition where 100 or more Time Segments, which have a maximum variation 0.62 seconds or lower, with no more than two (2) exceptions, then this condition is a +2.5 ALARM. Low-HRV is a predictive marker of low heart rate variability. (Parameter 9 of TABLE A). 
     2.0 Caution&gt;2.5 ALARM: If CAUTION or ALARM signals, for the above four conditions (SPS, AMo, DX, and DX/M), exist for 960 minutes with a gap (a lack of a Caution or an ALARM) of no more than 60 minutes, then the +2.0 Caution (calculated as 4 times 0.5 CAUTION points) becomes a +2.5 ALARM. This parameter is a predictive marker of low heart rate variability. (Parameter 10 of TABLE A). 
     Moreover, a baseline for SPS, AMo, and DX is established between the 10th and 500th Time Segment. Any deviation above 150% or below 50% of the baseline for more than 45 minutes triggers both a Caution and an ALARM of 2.5 points for any one of the three formulas. The preferred baseline time is 24 hours. TABLE C summarizes the parameters for establishing a baseline. 
     
       
         
               
             
               
               
               
             
           
               
                 TABLE C 
               
             
             
               
                   
               
               
                 Parameters for triggering a Caution/ALARM after a baseline 
               
               
                 has been established 
               
             
          
           
               
                 SPS 
                 AMo 
                 DX 
               
               
                   
               
               
                 start = 10 Time 
                 start = 10 Time 
                 start = 10 Time Segments 
               
               
                 Segments 
                 Segments 
               
               
                 end = 500 Time 
                 end = 500 Time 
                 end = 500 Time Segments 
               
               
                 Segments 
                 Segments 
               
               
                 ALARMhigh = 
                 ALARMhigh = 1.50 
                 ALARMhigh = 1.50 points 
               
               
                 1.50 points 
                 points 
               
               
                 ALARMlow = 
                 ALARMlow = 0.50 
                 ALARMlow = 0.50 points 
               
               
                 0.50 points 
                 points 
               
               
                 CAUTIONhigh = 
                 CAUTIONhigh = 1.50 
                 CAUTIONhigh = 1.50 points 
               
               
                 1.50 points 
                 points 
               
               
                 CAUTIONlow = 
                 CAUTIONlow = 0.50 
                 CAUTIONlow = 0.50 points 
               
               
                 0.50 points 
                 points 
               
               
                 ALARMtime = 
                 ALARMtime = 45.00 
                 ALARMtime = 45.00 
               
               
                 45.00 minutes 
                   
               
               
                 CAUTIONtime = 
                 CAUTIONtime = 
                 CAUTIONtime = 45.00 
               
               
                 45.00 
                 45.00 
               
               
                   
               
             
          
         
       
     
     The points assigned to these parameters in TABLE C for these formulas relative to the patient&#39;s own baseline may differ from the points attached to these parameters SPS, AMo, and DX when measuring these parameters SPS, AMo, and DX as Abs.SPS, Abs.AMo, and Abs.DX against predetermined upper and lower limits (see Tables 1a-c) as explained elsewhere in this specification. 
     Moreover, in applying the formula for converting a 2 point CAUTION signal to a 2.5 point ALARM signal the following time periods are employed. 
     SpecialTime 1 =60; 60 minutes maximum time after AMo first triggers a Caution that other formulas must also trigger a Caution (SPS, DX, DX/Median). Then the following must occur. 
     SpecialTime 2 =960; 960 combined total CAUTION minutes of the formulas (SPS, AMo, DX, DX/Median), for the CAUTIONs to convert to a 2.5 point ALARM, except as set forth below. 
     GapTimeIndivMax=210; If the combined total of gaps in the four formulas (SPS, AMo, DX, DX/Median), equals or exceeds 210 minutes, then reset to zero. A “gap” is a non-CAUTION status. 
     GapTimeWindow=60; if a gap occurs in any of the four formulas, (SPS, AMo, DX, DX/Median), that is 60 minutes or longer, then reset to zero. 
     Heart Rate: If the heart rate is 40 bpm or 135 bpm for more than 45 minutes, then this is −2.5 or +2.5 point ALARM. (Parameters 11 and 12 of TABLE A). 
     The parameters calculated by the following formulas, “a” through “e” and “f”, can be substituted for AMo and/or DX. Typically for each of AMo and/or DX replaced, one or more of parameters “a” through “e” and “f” are substituted. 
     (a) Standard Deviation Average Normal to Normal, SDANN: SDANN is a measure of the dispersion around the mean of NN Time Intervals in a five minute Time Segment, after ACRRs (Premature Ventricular Contractions and Atrial Fibrillation, if any) have been discarded, according to the formula. A value of 50 or lower in a SDANN Time Segment is a predictive marker of a serious cardiac condition. 
     
       
           SDANN ={square root over (( nΣx ) 2 −( Σx ) 2   /n ( n− 1))} 
       
     
     (b) Point Normal to Normal 50 milliseconds, PNN50: PNN50 is a measure of the concentration of Time Intervals at 50 milliseconds or lower during a five minute PNN50 Time Segment. A value of 50 milliseconds or lower in a PNN50 Time Segment is a predictive marker of a serious cardiac condition. 
     (c) Amplitude of the Median (AM): The Amplitude of the Median is the 47th Time Interval occurring in a Time Segment, e.g. if the 47th Time interval is 0.70 and occurs 21 times, them AM equal 21. 
     (d) Full Width at Half Maximum (FWHM) The Full Width at Half Maximum is a measure of the dispersion of Time Intervals. The value of Half Maximum is one half of (AMo) or (AM) and the Full Width is the length of a horizontal line (DX) across the vertical line at right angles to the vertical line of (AMo) or (AM) through the point of Half Maximum. 
     (e and f) Kurtosis: Kurtosis is the description of the Gaussian distribution of data points. A Gaussian curve that is peaked is leptokurtic the vertical height of which is equivalent to AMo, FIG. 1 a . A Gaussian curve that is flat is platykurtic the horizontal base of which is equivalent to DX, FIG. 1 b.    
     Another available parameter is: 
     (g) ANN: Average of the NN values in a Time Segment. When ANN exceeds a predetermined percentage of the baseline values for a predetermined period of time, then a CAUTION or ALARM may be signaled. 
     Patient: A patient is anyone whose Time Intervals are measured. 
     OK: The patient&#39;s physical condition is normal and not stressed. 
     Caution: The patient has a potentially unhealthy stress condition. 
     ALARM: An ALARM is present when the patient&#39;s current HRV Status indicates a state of low heart rate variability, or a state of high heart rate variability, or ACRR&#39;s, for a predetermined number of Time Segments or a predetermined period of time. 
     Motion Sensor: A transducer detects a range of motions from, no motion, to slight motion, to moderate motion to heavy motion and over load. No motion for a predetermined period of time and a heart or pulse rate indicates a Comatose ALARM. Slight motion and a heart or pulse rate indicate sleep. Heavy motion indicates exercise and over load (spike) followed by no motion, indicates a fall. 
     Comatose ALARM: If Time Intervals are detected but no motion is detected for 30 or more minutes, then this is a +2.5 point Comatose ALARM. 
     Cardiac Arrest ALARM: If no Time Intervals are detected for 15 or more seconds and the galvanic skin response sensor indicates the ECG electrodes or the pulse sensor is in contact with the patient, then this is a +2.5 point Cardiac Arrest ALARM. 
     Long Term Cardiac Caution: If the heart rate is raised to, for example, 150 bpm, as is sometimes the case during a stress test, and a reading of the patient&#39;s heart rate is taken at the end of this strenuous exercise, and a second heart rate reading is taken one minute later, then if the difference between the two heart rates is 12 bpm or less, then the patient has a long term cardiac caution condition. If the heart rate is raised to say an aerobic target heart of, for example, 115 to 130 bpm, and a reading of the patient&#39;s heart rate is taken at the end of this aerobic exercise, and a second heart rate reading is taken one minute later, then if the difference between the two heart rates is 8 to 10 bpm or less, then the patient has a long term cardiac caution condition. The patient&#39;s functional and stress states may be displayed to the patient or a health care provider in an alphanumeric fashion, utilizing the HRV Status output. This enables the patient or health care provider to determine the patient&#39;s stress status substantially instantaneously at any time or place, and to attain a state of effective cardiovascular fitness. 
     Detection of abnormal heart rate variability in a series of Time Segments can therefore be used to signal a health care provider, or pacemaker, or cardioverter defibrillator with a pacemaker, to intervene according to the invention, or to indicate that the heart is being over stressed by the particular activity (e.g. physical, psychogenic) being engaged in. 
     Also according to the invention, a pacemaker or a cardioverter defibrillator with a pacemaker can be programmed to provide a normal, therapeutic heart rate variability rather than an unnatural steady beat as in the prior art. This may be accomplished by, (1) recording the patient&#39;s normal, variable heart rate, or (2) the normal, variable heart rhythm of an individual most nearly matching the patient&#39;s age, sex, race, build and athletic condition, or (3) using a random pulse generator that produces a normal, variable histographic heart rate, all in conjunction with an impedance pacemaker, (a pacemaker that detects respiration). 
     The details for an apparatus to perform the process aspects of the present invention are provided by U.S. Pat. No. 5,718,235, incorporated herein by reference. See, for example, FIG. 5 of U.S. Pat. No. 5,718,235. However, of course, the apparatus would be modified where necessary to contain a software program to perform the calculations and comparisons to perform the process of the present invention. Also, it could be modified to include interval detectors such as ultrasound doppler sensors, a piezo electric microphone, or any other appropriate sensor. 
     OBJECTS OF THE INVENTION 
     It is therefore an object of this invention to provide a method and apparatus for determining the patient&#39;s stress state. 
     Another preferred object of the invention is to provide such apparatus, which allows the patient to exercise in a stress state which will bring about a maximum conditioning effect. 
     A further preferred object of the invention is to provide such apparatus and method that the patient will be notified of non-optimal or an ALARM or Caution distress state. 
     Still another preferred object of the invention is to detect stress and distress states from simple parameters derived from the recording of a plurality of durations of successive Time Intervals between heart beats. 
     Still another preferred object of the invention is to detect cardiac distress. 
     Still another preferred object of the invention is to detect abnormal heart rate variability over a relatively short period of time and to signal this abnormality to a health care provider, or a pacemaker or a cardioverter defibrillator with a pacemaker, to initiate intervention. 
     Still another preferred object of the invention is to cause a pacemaker or cardioverter defibrillator with a pacemaker, to pace a heart with a normal heart rate variability. 
     Other preferred objects of the invention will be apparent from the following disclosure. 
     The invention accordingly comprises a method comprising several steps and the relation of one or more of such steps with respect to each of the others, and the apparatus embodying features of construction, elements, and arrangements of parts, which are adapted to effect such steps, all as exemplified in the following detailed disclosure. 
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS 
     For a fuller understanding of the nature and objects of the invention reference should be had to the following detailed description taken in connection with the accompanying drawings in which: the same reference characters refer to the same elements throughout the several views of the drawings. 
     FIG. 1 a  shows a plot of a Platykurtic Curve. 
     FIG. 1 b  shows a plot of a Leptokurtic Curve. 
     FIG. 2 a  shows a plot of Abs SPS versus time. 
     FIG. 2 b  shows a plot of Abs AMo versus time. 
     FIG. 2 c  shows a plot of Abs DX versus time. 
     FIG. 2 d  shows a plot of Abs DX/Median versus time. 
     FIG. 2 e  shows a plot of Low HRV versus time. 
     FIG. 2 f  shows a plot of ACRR versus time. 
     FIG. 2 g  shows a plot of Heart Rate versus time. 
     FIG. 2 h  shows a plot of HRV Status versus time. 
     FIG. 3 a  shows a plot of Abs SPS versus time. 
     FIG. 3 b  shows a plot of Abs AMo versus time. 
     FIG. 3 c  shows a plot of Abs DX versus time. 
     FIG. 3 d  shows a plot of Abs DX/Median versus time. 
     FIG. 3 e  shows a plot of Low HRV versus time. 
     FIG. 3 f  shows a plot of ACRR versus time. 
     FIG. 3 g  shows a plot of Heart Rate versus time. 
     FIG. 3 h  shows a plot of HRV Status versus time. 
     FIG. 4 a  shows a plot of Abs SPS versus time. 
     FIG. 4 b  shows a plot of Abs AMo versus time. 
     FIG. 4 c  shows a plot of Abs DX versus time. 
     FIG. 4 d  shows a plot of Abs DX/Median versus time. 
     FIG. 4 e  shows a plot of Low HRV versus time. 
     FIG. 4 f  shows a plot of ACRR versus time. 
     FIG. 4 g  shows a plot of Heart Rate versus time. 
     FIG. 4 h  shows a plot of HRV Status versus time. 
     FIG. 5 a  shows a plot of Abs SPS versus time. 
     FIG. 5 b  shows a plot of Abs AMo versus time. 
     FIG. 5 c  shows a plot of Abs DX versus time. 
     FIG. 5 d  shows a plot of DX/Median versus time. 
     FIG. 5 e  shows a plot of Low HRV versus time. 
     FIG. 5 f  shows a plot of ACRR versus time. 
     FIG. 5 g  shows a plot of Heart Rate versus time. 
     FIG. 5 h  shows a plot of HRV Status versus time. 
     FIG. 6 a  shows a plot of Abs SPS versus time. 
     FIG. 6 b  shows a plot of Abs AMo versus time. 
     FIG. 6 c  shows a plot of Abs DX versus time. 
     FIG. 6 d  shows a plot of DX/Median versus time. 
     FIG. 6 e  shows a plot of Low HRV versus time. 
     FIG. 6 f  shows a plot of ACRR versus time. 
     FIG. 6 g  shows a plot of Heart Rate versus time. 
     FIG. 6 h  shows a plot of HRV Status versus time. 
     FIGS. 7 a ,  7   b , and  7   c  show people carrying a cellular telephone, which would be silently activated to Dial 911, or a central monitoring station when an ALARM condition was predicted by the wrist monitor concealed under their sleeves. 
     FIG. 8 schematically shows an overall view of a process decision tree diagram of an embodiment of the present invention. 
     FIGS. 9 a-f  show portions of the decision tree diagram. 
     FIG. 10, shows a Recharge Base Station. 
     FIG. 11 shows a schematic diagram of the components of the wrist monitor. 
     FIG. 12 shows an EMS vehicle and personnel rescuing a patient who may have experienced a Comatose ALARM, or a Heart Attack, or suffered an accident. 
    
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
     The present invention includes analysis of the Kurtosis of patient data. Kurtosis is the degree of peakedness or flatness of a probability distribution, relative to the normal distribution with the same variance. Kurtosis is the description of the Gaussian distribution of data points and involves the concepts of leptokurtic and platykurtic curves. 
     A leptokuric curve pertains to a probability distribution more heavily concentrated around the mean, i.e., having a sharper, narrower peak, than the normal distribution with the same variance. Moreover, a leptokurtic curve is a Gaussian curve that is peaked and has a vertical height equivalent to AMo as shown in FIG. 1 a.    
     A platykurtic curve of a probability distribution has a broader, flatter peak than the normal distribution with the same variance. Moreover, a platykurtic curve is a Gaussian curve that is flat and has a horizontal base equivalent to DX as shown in FIG. 1 b.    
     A mesokurtic curve (not shown) is normal. 
     The formula for kurtosis is Formula I as follows: 
     
       
         Kurtosis=(Σ( X−μ ) 4 /( Nδ ) 4 )−3  I, 
       
     
     wherein δ is the standard deviation. 
     In Formula I, the parameter (Σ(X−μ) 4 /(N δ) 4 ) equals a 4  defined as in Formula II.                a   4     =         (       ∑     i   =   1     k          (           f   i          (       X   i     -     X   _       )       4     /   n     )       )       s   4       .           II                              
     In the Formula II, a 4 =3 is mesokurtic (normal distribution); a 4 &gt;3 is leptokurtic; and a 4 &lt;3 is platykurtic. The formula evolves from a value of 3 down to a definition of DX, and evolves from a value of 3 up to a definition of AMo. 
     The absolute ALARM settings for DX and AMo are as follows: 
     Decreased HRV DX ALARM is ≦0.06; 
     Decreased HRV AMo ALARM is ≧90; 
     Increased HRV DX ALARM is ≧0.5; and 
     Increased HRV AMo ALARM is ≦10. 
     For any person, but especially for an ambulatory person age 18-54, a kurtosis value (a 4 )≧30 is an Increased HRV ALARM. and a kurtosis value (a 4 )≦0.3 is an Decreased HRV ALARM., for a ratio of at least about 28 to 31 out of 50 Time Segments, wherein at least about 30 Time Segments are measured. 
     A patient&#39;s heart rate can be measured and then analysis of the Kurtosis of the heart rate leads to sympathetic and parasympathetic heart parameters which can be employed to predict arrhythmia. 
     TABLES 1a, 1b and 1c list the names of the parameters and the ranges of predetermined normal values of these parameters. This results in formulas used to predict arrhythmia. TABLES 1a, 1b and 1c list the points assigned to Caution or ALARM conditions recorded. If at any time the points total 2.0 or less, the patient&#39;s HRV health is satisfactory. In the calculations up to 3 high outliers and 3 low outliers per Time Segment are permitted. 
     
       
         
               
               
               
               
               
               
               
             
               
               
               
               
               
               
               
             
           
               
                 TABLE 1a 
               
               
                   
               
               
                   
                   
                 Standard 
                 Standard 
                 Hi-Risk 
                   
                   
               
               
                 Names of 
                   
                 Age 18 to 54 
                 Age 55+ 
                 All Ages 
                 ER 
                 Apnea 
               
               
                 Parameters Used 
                 Points 
                 (predict) 
                 (predict) 
                 (predict) 
                 (predict) 
                 (detect) 
               
               
                   
               
             
             
               
                   
               
             
          
           
               
                 (defaults) 
                   
                   
                   
                   
                   
                   
               
               
                 resolution 
                   
                 0.06 
                 0.06 
                 0.20 
                 0.20 
                 0.06 
               
               
                 outliers (high/low) 
                   
                 3 
                 3 
                 3 
                 3 
                 3 
               
               
                 segment size 
                   
                 101 
                 101 
                 101 
                 101 
                 101 
               
               
                 (intervals) 
               
               
                 (ABS.SPS.HI) 
               
               
                 ALARMHIGH 
                   
                 48 
                 48 
                 48 
                 48 
                 48 
               
               
                 ALARMtrigger 
                 +1.0 
                 30 
                 15 
                 560 
                 48 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 +0.5 
                 5 
                 10 
                 460 
                 45 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 700 
                 50 
               
               
                 (ABS.SPS.LO) 
               
               
                 ALARMLOW 
                   
                 2.50 
                 4.00 
                 3.50 
                 6.00 
                 4.00 
               
               
                 ALARMtrigger 
                 −1.0 
                 25 
                 15 
                 35 
                 10 
                 37 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 40 
                 50 
                 50 
               
               
                 Cautiontrigger 
                 −0.5 
                 15 
                 10 
                 30 
                 9 
                 37 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 40 
                 50 
                 50 
               
               
                 (ABS.AMo.HI) 
               
               
                 ALARMHIGH 
                   
                 90 
                 90 
                 95 
                 95 
                 n/a 
               
               
                 ALARMtrigger 
                 +1.0 
                 30 
                 15 
                 575 
                 48 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 +0.5 
                 15 
                 10 
                 460 
                 45 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 (ABS.AMo.LOW) 
               
               
                 ALARMLOW 
                   
                 10 
                 10 
                 10 
                 10 
                 n/a 
               
               
                 ALARMtrigger 
                 −1.0 
                 25 
                 20 
                 7 
                 25 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 10 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 −0.5 
                 15 
                 15 
                 5 
                 20 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 10 
                 50 
                 n/a 
               
               
                   
               
             
          
         
       
     
     
       
         
               
               
               
               
               
               
               
             
               
               
               
               
               
               
               
             
           
               
                   
                 TABLE 1b 
               
               
                   
                   
               
               
                   
                   
                 Standard 
                 Standard 
                 Hi-Risk 
                   
                   
               
               
                   
                   
                 Age 18 to 54 
                 Age 55+ 
                 All Ages 
                 ER 
                 Apnea 
               
               
                   
                 Points 
                 (predict) 
                 (predict) 
                 (predict) 
                 (predict) 
                 (detect) 
               
               
                   
                   
               
             
             
               
                   
               
             
          
           
               
                 Name of 
                   
                   
                   
                   
                   
                   
               
               
                 Parameters 
               
               
                 Used 
               
               
                 (defaults) 
               
               
                 resolution 
                   
                 0.06 
                 0.06 
                 0.20 
                 0.20 
                 0.06 
               
               
                 outliers (high/low) 
                   
                 3 
                 3 
                 3 
                 3 
                 3 
               
               
                 segment size 
                   
                 101 
                 101 
                 101 
                 101 
                 101 
               
               
                 (ABS.DX.LO) 
                   
               
               
                 ALARMLOW 
                   
                 0.06 
                 0.06 
                 0.06 
                 0.06 
                 n/a 
               
               
                 ALARMtrigger 
                 −1.0 
                 25 
                 20 
                 575 
                 48 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 −0.5 
                 10 
                 15 
                 460 
                 45 
                 n/a 
               
               
                 Caution segments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 (ABS.DX.HI) 
               
               
                 ALARMHIGH 
                   
                 0.50 
                 0.50 
                 0.50 
                 0.50 
                 n/a 
               
               
                 ALARMtrigger 
                 +1.0 
                 30 
                 15 
                 40 
                 15 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 50 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 +0.5 
                 15 
                 10 
                 35 
                 10 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 50 
                 50 
                 n/a 
               
               
                 Name of Formulas 
               
               
                 Used 
               
               
                 (ABS.DX/M.LO) 
               
               
                 ALARMLO 
                   
                 0.02 
                 0.02 
                 0.02 
                 0.02 
                 n/a 
               
               
                 ALARMtrigger 
                 −1.0 
                 25 
                 15 
                 575 
                 48 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 −0.5 
                 5 
                 5 
                 460 
                 45 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 700 
                 50 
                 n/a 
               
               
                 (ABS.DX/M.HI) 
               
               
                 ALARMHIGH 
                   
                 0.425 
                 0.425 
                 0.425 
                 0.425 
                 n/a 
               
               
                 ALARMtrigger 
                 +1.0 
                 25 
                 20 
                 45 
                 20 
                 n/a 
               
               
                 ALARMsegments 
                   
                 50 
                 50 
                 50 
                 50 
                 n/a 
               
               
                 Cautiontrigger 
                 +0.5 
                 15 
                 15 
                 40 
                 18 
                 n/a 
               
               
                 Cautionsegments 
                   
                 50 
                 50 
                 50 
                 50 
                 n/a 
               
               
                 SpecialTime 1 
                 +2.5 
                 60 
                 60 
                 60 
                   
                 n/a 
               
               
                 (minutes) 
               
               
                 SpecialTime 2 to 
                   
                 960 
                 960 
                 960 
                   
                 n/a 
               
               
                 shift CAUTION to 
               
               
                 ALARM (minutes) 
               
               
                 GapTimeIndividual 
                   
                 210 
                 210 
                 210 
                   
                 n/a 
               
               
                 Maximum 
               
               
                 (minutes) 
               
               
                 GapTime Window 
                   
                 60 
                 60 
                 60 
                   
                 n/a 
               
               
                 (minutes) 
               
               
                   
               
             
          
         
       
     
     
       
         
               
               
               
               
               
               
               
             
               
               
               
               
               
               
               
             
           
               
                   
                 TABLE 1c 
               
               
                   
                   
               
               
                   
                   
                 Standard 
                 Standard 
                 Hi-Risk 
                   
                   
               
               
                   
                   
                 Age 18 to 54 
                 Age 55+ 
                 All Ages 
                 ER 
                 Apnea 
               
               
                   
                 Points 
                 (predict) 
                 (predict) 
                 (predict) 
                 (predict) 
                 (detect) 
               
               
                   
                   
               
             
             
               
                   
               
             
          
           
               
                 Names of 
                   
                   
                   
                   
                   
                   
               
               
                 Parameters Used 
               
               
                 (defaults) 
               
               
                 resolution 
                   
                 0.06 
                 0.06 
                 0.20 
                 0.20 
                 0.06 
               
               
                 outliers 
                   
                 3 
                 3 
                 3 
                 3 
                 3 
               
               
                 segment size 
                   
                 101 
                 101 
                 101 
                 101 
                 101 
               
               
                 Low-HRV 
               
               
                 segments 
                 +2.5 
                 100 
                 100 
                 100 
                 100 
                 n/a 
               
               
                 maximum 
                   
                 0.62 
                 0.62 
                 0.62 
                 0.62 
                 n/a 
               
               
                 variation (seconds) 
               
               
                 segment exceptions 
                   
                 2 
                 2 
                 2 
                 2 
                 n/a 
               
               
                 ACRR 
               
               
                 ALARMhigh 
                 +2.5 
                 50 
                 65 
                 30 
                 50 
                 n/a 
               
               
                 Cautionhigh 
                 +2.5 
                 50 
                 65 
                 30 
                 50 
                 n/a 
               
               
                 ALARMtime 
                   
                 35 
                 52 
                 135 
                 40 
                 n/a 
               
               
                 Cautiontime 
                   
                 35 
                 52 
                 135 
                 40 
                 n/a 
               
               
                 HEART RATE 
               
               
                 (bpm) 
               
               
                 ALARMhigh 
                 +2.5 
                 135 
                 135 
                 120 
                 135 
                 n/a 
               
               
                 ALARMlow 
                 +2.5 
                 45 
                 45 
                 40 
                 45 
                 n/a 
               
               
                 CAUTIONhigh 
                 +2.5 
                 135 
                 135 
                 120 
                 100 
                 n/a 
               
               
                 CAUTIONlow 
                 +2.5 
                 45 
                 45 
                 40 
                 45 
                 n/a 
               
               
                 ALARMtime 
                   
                 45 
                 45 
                 60 
                 45 
                 n/a 
               
               
                 (minutes) 
               
               
                 Names of Formulas 
               
               
                 Used 
               
               
                 Apnea detection 
               
               
                 ALARMHIGH 
                   
                 n/a 
                 n/a 
                 n/a 
                 n/a 
                 3 
               
               
                 cautionhigh 
                   
                 n/a 
                 n/a 
                 n/a 
                 n/a 
                 3 
               
               
                 threshold 
                   
                 n/a 
                 n/a 
                 n/a 
                 n/a 
                 120 
               
               
                 outof 
                   
                 n/a 
                 n/a 
                 n/a 
                 n/a 
                 9 
               
               
                   
               
             
          
         
       
     
     If at any time the points total +2.5 or higher, or −2.5 or lower, then the patient is at risk of experiencing a potentially fatal arrhythmia within the next two to 24 hours. 
     TABLES 1a, 1b and 1c set forth the following: 
     The settings predicting an adverse event for ambulatory patient&#39;s age 18 to 54; 
     the settings predicting an adverse event for ambulatory patients age 55 and older; 
     the settings predicting an adverse event for High Risk patients, e.g. patients of all ages in the Cardiac Care Unit (CCU); 
     the settings predicting an adverse event for patients of all ages in the Emergency Room (ER); and the settings for detecting a sleep apnea arousal. 
     In particular, the invention relates to the discovery that monitoring a variety of Kurtosis parameters for sympathetic and parasympathetic heart activity and then measuring these parameters against predetermined limits results in an accurate predictor of heart arrhythmia. Thus, part of the invention is that the inventor has determined key upper and lower values of ranges of these parameters for various classes of patients. Values within the ranges are normal. These parameters for a patient are measured and a score is calculated. When the score is sufficiently above or below normal, a caution signal or alarm signal is generated. 
     Knowing these predetermined values for a variety of parameters disclosed by this specification enables one skilled in the art to select other Kurtosis parameters of low variability or high variability activity and determine high and low values of these parameters which define normal ranges and values which predict arrhythmia. Measurement of more than one parameter leads to more accurate predictions. 
     In TABLES 1a, 1b and 1c, the first columns under “(defaults)” list resolution which is the number of 0.02 Time Intervals whose values are averaged together. These first columns also list outliers, which are the three longest Time Intervals and the 3 shortest Time Intervals in a Time Segment, which are deleted before any formula calculations are made. These first columns also list segment size, which is the number of NN Time Intervals in a Time Segment after ACRRs are removed and stored separately, and MARRs (FIG. 9 d ) are removed and stored separately, and outliers are deleted. 
     Post-MI (myocardial infarction) patients will use one of the two Standard settings, depending on age. If, in a 24 hour period ALARMS are triggered and the patient experiences an adverse cardiac event, then the Hi-Risk settings are substituted for a 24 hour period. If the patient still triggers ALARMS and the patient does not experience an adverse cardiac event, then the software would have to be customized for that patient. 
     These first columns also list the titles to the group of absolute formulas ABS.SPS; ABS.AMo; ABS.DX; ABS.DX/M; low-HRV; ACRR; Heart Rate; and NN-Acceleration relating to the SPS formulas. 
     The term “ABS” is an abbreviation for “absolute.” Thus, these values are applied to all patients in the specified category. For example, ABS.SPS is an absolute value (upper or lower limit) of SPS (sympathetic/parasympathetic stress). The patient&#39;s measured value of SPS is compared to the ABS.SPS limits to determine if the patient&#39;s health is in danger. 
     TABLE  1   a  discloses the parameters relating to upper and lower limits for SPS as well as upper and lower limits for AMo. 
     TABLE  1   b  discloses the parameters relating to the upper and lower limits of DX as well as the upper and lower limits of DX/M. TABLE  1   b  also provides for Special Time and Gap Time parameters. 
     TABLE  1   c  discloses low-HRV (defined above); ACRR (defined above); heart rate; and NN-Acceleration. 
     For example, for patients age 18 to 54, if a patient records 30 or more Time Segments out of 50 Time Segments where the patient&#39;s SPS value is 48 or higher, or 25 or more Time Segments out of 50 Time Segments where the patient&#39;s SPS value is 2.50 or lower, then the patient is experiencing an SPS ALARM condition, which is assigned a value +1.0 points if the formula value is 48 or larger, and a value of −1.0 points if the value is 2.50, or less. 
     If the patient records 5 to 29 Time Segments out of 50 Time Segments, where the patient&#39;s SPS value is 48 or higher, then the patient is experiencing a Caution condition, which is assigned a value of +0.5 points. If a patient records 15 to 24 Time Segments out of 50 Time Segments, where the patient&#39;s SPS value is an SPS value of 2.50 or lower, then patient is experiencing an SPS Caution condition, which is assigned a value of −0.5 points. 
     The same analysis set forth above, applies to patients in the other categories of TABLES 1a-c. 
     FIGS. 2 a  through  2   g  are charts, which deal with a patient&#39;s cardiac condition. The total points, if any, are totaled in the top chart, FIG. 2 h,  HRV Status. Points are assigned to each cardiac condition as set forth in TABLES 1a, 1b and 1c. 
     In FIGS. 2 a  through  2   d,  a Caution condition is assigned a value of either +0.5 if decreased variability is indicated, or −0.5 if increased variability is indicated. An ALARM condition is assigned a value of either +1.0 if decreased variability is indicated, or −1.0 if increased variability is indicated. 
     In FIG. 2 e  an ACRR ALARM condition (there is no Caution) is assigned a value of either +2.5 or −2.5, depending upon the cardiac condition indicated in FIGS. 2 a  through  2   d,  which is either decreased variability and thus an ALARM of +2.5, or increased variability, and thus an ALARM of −2.5. If neither a decreased nor an increased variability is indicated in FIGS. 2 a  through  2   d,  then the ALARM is +2.5, with no more than two consecutive time intervals which did not qualify as an ACRR Time Interval. 
     In FIG. 2 f  a low HRV ALARM condition (there is no Caution) is assigned a value of +2.5. 
     In FIG. 2 g  a Heart Rate ALARM condition, (there is no Caution) is assigned a value of either +2.5 or −2.5, depending upon the cardiac condition indicated in FIGS. 2 a  through  2   d,  which is either decreased variability and thus an ALARM of +2.5, or increased variability, and thus an ALARM of −2.5. If neither a decreased nor an increased variability is indicated in FIGS. 2 a  through  2   d,  then the ALARM is +2.5. 
     In FIG. 2 h,  numeral  141  indicates the +2.5 HRV Status ALARM level of decreased variability. Numeral  143  indicates +2.0 HRV Status Caution level of decreased variability. Numeral  145  indicates zero, 0, HRV Status level. Numeral  147  indicates −2.0 HRV Status Caution level of increased variability. Numeral  149  indicates −2.5 HRV Status ALARM level of increased variability. Numeral  151  indicates the sum of all the Cautions and/or ALARMS as may be recorded in FIGS. 2 a  through  2   g.    
     In FIG. 2 a,  numeral  101  indicates the decreased variability ALARM level for the formula Abs SPS. Numeral  103  indicates the increased variability ALARM level for the formula Abs SPS. Numeral  105  indicates the patient&#39;s recorded value for the Abs SPS formula. 
     In FIG. 2 b,  numeral  107  indicates the decreased variability ALARM level for the formulas Abs AMo. Numeral  109  indicates the increased variability ALARM level for the formula Abs AMo. Numeral  111  indicates the patient&#39;s recorded value for the Abs AMo formula. 
     In FIG. 2 c,  numeral  113  indicates the decreased variability ALARM level for the formula Abs DX. Numeral  115  indicates the increased variability ALARM level for the formula Abs DX. numeral  117  indicates the patient&#39;s recorded value for the Abs DX formula. 
     In FIG. 2 d,  numeral  119  indicates the decreased variability ALARM level for the formula Abs DX/Median. Numeral  121  indicates the increased variability ALARM level for the formula DX/Median. Numeral  123  indicates the patient&#39;s recorded value for the DX/Median formula. 
     In FIG. 2 e,  numeral  129  indicates the ALARM level for Low HRV. Numeral  131  indicates the patient&#39;s recorded level for Low HRV. 
     In FIG. 2 f,  numeral  125  indicates the upper ALARM limit of ACRRs per 101 NN heart beats. Numeral  127  indicates the patient&#39;s recorded value for ACRRs. 
     In FIG. 2 g,  numeral  133  indicates the upper ALARM level for Heart Rate. Numeral  137  indicates the lower ALARM level for Heart rate. Numeral  135  indicates the difference between numeral  133  and numeral  137 .  139  indicates the patient&#39;s recorded level for Heart Rate. 
     FIGS. 3 a  through  3   g  are charts, which deal with a patient&#39;s cardiac condition. The total points, if any, are totaled in the top chart, FIG. 3 h,  HRV Status. Points are assigned to each cardiac condition as set forth in TABLES 1a, 1b and 1c. 
     In FIGS. 3 a  through  3   e,  numeral  150  indicates both decreased and increased heart rate variability Cautions, and numeral  152  , ALARMS. 
     In FIG. 3 f,  numeral  152  indicates both decreased and increased heart rate variability ALARMS. 
     FIG. 3 g  indicates heart rate. 
     In FIG. 3 h,  numeral  156  indicates first a decreased heart variability ALARM, then an increased heart variability ALARM, and then finally a decreased heart variability ALARM. 
     FIGS. 4 a  through  4   g  are charts, which deal with a patient&#39;s cardiac condition. The total points, if any, are totaled in the top chart, FIG. 4 h,  HRV Status. Points are assigned to each cardiac condition as set forth in TABLES 1a, 1b and 1c. 
     In FIGS. 4 a  through  4   e  numeral  152  (if present) indicates increased heart rate variability ALARMS. 
     In FIG. 4 f,  numeral  152  indicates both decreased and increased heart rate variability ALARMS. 
     FIG. 4 g  indicates heart rate. 
     In FIG. 4 h,  numeral  154  indicates an increased variability HRV Status Caution, and numeral  156  indicates an increased variability HRV Status ALARM. 
     FIGS. 5 a  through  5   g  are charts, which deal with patient&#39;s cardiac condition. The total points, if any, are totaled in the top chart, FIG. 5 h,  HRV Status. Points are assigned to each cardiac condition as set forth in TABLES 1a, 1b and 1c. 
     In FIG. 5 e,  numeral  152  indicates a decreased variability Low HRV ALARM. 
     In FIG. 5 h,  numeral  156  indicates a decreased variability HRV Status ALARM. 
     FIGS. 6 a  through  6   g  are charts, which deal with patient&#39;s cardiac condition. The total points, if any, are totaled in the top chart, FIG. 6 h,  HRV Status. Points are assigned to each cardiac condition as set forth in TABLES 1a, 1b and 1c. 
     In FIGS. 6 a  through  6   g,  several high variability CAUTIONS, numeral  150 , and ALARMS, numeral  152  are indicated. 
     Parameter Ranges 
     The parameter upper and lower limits listed in the Tables 1a-c may be employed over a range of typically less than about ±10%, preferably less than about ±5%. 
     For example: For SPS (Sympathetic Parasympathetic Stress), for ambulatory patients age 18 to 54, the upper limit listed on Table 1a is 48 for at least 30 out of 50 Time Segments. However, in practice an upper limit is selected in the range from 46 to 50 for at least 30 out of 50 Time Segments. 
     In general, the CAUTION or ALARM signal for the particular parameter may operate suitably if the number of trigger segments (listed in the Tables 1a-c for that respective parameter) are adjusted by ±2, preferably ±1, so long as the adjustment is at most 20% of the number of trigger segments (listed in the Tables 1a-c for that respective parameter) rounded off to the nearest integer. 
     For example, for SPS (Sympathetic Parasympathetic Stress), for ambulatory patients age 18 to 54, Table 1a lists an ABS.SPS.HI Caution signal when the value for SPS is greater than or equal to the upper limit of 48 for a ratio of at least 5 of 50 Time Segments. A suitable range for “about 5” is 4 to 6 out of 50 Time Segments. Table 1a lists an ABS.SPS.HI ALARM signal when the value for SPS is greater than or equal to the upper limit of 48 for a ratio of at least about 30 out of 50 Time Segments. A practical range for a ratio of “about 30” is 28 to 32 out of 50 Time Segments. 
     Moreover, the number of CAUTION segments and/or ALARM segments of 101 Time Intervals can be reduced by as much as 40%, preferably by as much as 20% and still be used to predict heart conditions, so long as the ratios of trigger segments to Caution segments and ALARM segments, of Tables 1a, 1b, and 1c with at most the above-described adjustments, are employed. Thus, in obtaining these ratios, at least 30, preferably at least about 50 Time Segments are measured. 
     For example, for ABS.SPS.HI ALARM of a standard ambulatory person age 18 to 54, Table 1a lists 30 out of 50 Time Segments to signal an alarm. However, 24 out of 30 Time Segments could also signal an alarm because this maintains the ratio listed by Table 1a. 
     Thus, ranges for other parameters of the present invention for a standard ambulatory person age 18 to 54 are described as follows. 
     For the SPS lower limit, for ambulatory patients age 18 to 54, of about 2.5, a CAUTION is signaled when the value for SPS is less than or equal to the lower limit for a ratio of at least about 13 to 17 out of 50 Time Segments, and an ALARM is signaled when the value for SPS is less than or equal to the lower limit for a ratio of at least about 23-27 out of 50 Time Segments. In obtaining these ratios, at least about 30, preferably at least about 50, Time Segments are measured. 
     For AMo (Amplitude of the Mode) for ambulatory patients age 18 to 54, the upper limit is about 85 to about 95 and a CAUTION is signaled when the value for AMo is greater than or equal to the upper limit for a ratio of at least about 13 to 17 out of 50 Time Segments, and an ALARM is signaled when the value for AMo is greater than or equal to the upper limit for a ratio of at least about 28 to 32 out of 50 Time Segments, wherein at least about 30, preferably at least about 50, Time Segments are measured. 
     Also, for AMo for ambulatory patients age 18 to 54, the lower limit is about 8 to about 12, and a Caution is signaled when the value for AMo is less than or equal to the lower limit for a ratio of at least about 13 to 17 out of 50 Time Segments, and an ALARM is signaled when the value for AMo is less than or equal to the lower limit for a ratio of at least about 23 to 27 out of 50 Time Segments, wherein at least about 30, preferably at least about 50 Time Segments are measured. 
     For DX (Delta X) for ambulatory patients age 18 to 54, the upper limit is about 0.4 to about 0.6 and a Caution is signaled when the value for DX is greater than or equal to the upper limit for a ratio of at least about 13 to about 17 out of 50 Time Segments, and an ALARM is signaled when the value for DX is greater than or equal to the upper limit for a ratio of at least about 28 to 32 out of 50 Time Segments, wherein at least about 30, preferably at least about 50 Time Segments are measured. 
     Also, for DX (Delta X) for ambulatory patients age 18 to 54, the lower limit is about 0.05 to about 0.07 and a Caution is signaled when the value for DX is less than or equal to the lower limit for a ratio of at least about 8 to about 12 out of 50 Time Segments, and an ALARM is signaled when the value for DX is less than or equal to the lower limit for a ratio of at least about 23 to about 27 out of 50 Time Segments, wherein at least about 30, preferably at least about 50 Time Segments are measured. 
     For DX/M for ambulatory patients age 18 to 54, the upper limit is about 0.4 to 0.5 and a Caution is signaled when the value for DX/M is greater than or equal to the upper limit for a ratio of at least about 13 to about 17 out of 50 Time Segments, and an ALARM is signaled when the value for DX/M is greater than or equal to the upper limit for a ratio of at least about 23 to about 27 out of 50 Time Segments, wherein at least about 30, preferably at least about 50, Time Segments are measured. 
     Also, for DX/M for ambulatory patients age 18 to 54, the lower limit Caution is about 0.015 to about 0.025, a Caution is signaled when the value for DX/M is less than or equal to the lower limit for a ratio of at least about 4 to 6 out of 50 Time Segments, and an ALARM is signaled when the value for DX/M is less than or equal to the lower limit for a ratio of at least about 23 to 27 out of 50 Time Segments, wherein at least about 30, preferably at least about 50, Time Segments are measured. 
     For Low-HR, Table 1c lists a maximum variation of 0.62 seconds or lower for 100 or more Time Segments with no more than 2 exceptions. The maximum variation may be selected from a range of about 0.56 to about 0.68 seconds. 
     Table 1c lists ACRRs, for a standard 18 to 54 year old person, as when the present Time Interval differs from the previous Time Interval by about +25% or about −25%, and this situation occurs for a ratio of about 50 or more times while accumulating a Time Segment of 101 NN Time Intervals. If this condition persists for 35 minutes, or longer, then this is either a +2.5 or −2.5 point ALARM. It is suitable to select a time from 30 to 40 minutes to signal an ALARM. 
     Pacemaker and Cardiodefibrillator with a Pacemaker 
     At present, pacing is accomplished by making all beats the same duration in time. TABLE 2 is a pacing schedule that can be incorporated in an implantable cardioverter defibrillator, which induces much more natural pacing. Also, TABLE 2 shows the typical longest and shortest values of Time Intervals in a Time Segment and subtracts the two numbers to calculate DX. 
     
       
         
               
               
               
               
               
               
               
             
               
               
               
               
               
               
               
             
           
               
                 TABLE 2 
               
               
                   
               
               
                   
                   
                   
                 beats 
                   
                   
                 (Longest minus 
               
               
                 Breaths/ 
                   
                 Heart Rate 
                 per min. 
                   
                 AMo 
                 shortest) 
               
               
                 Minute 
                   
                 (sec) 
                 (bpm) 
                 AMo 
                 Secs 
                 DX 
               
               
                   
               
             
             
               
                   
               
             
          
           
               
                  24 &gt; 27+ 
                   
                 0.44 
                   
                   
                   
                 (0.50 − 0.42) 
               
               
                   
                 Mode 
                 0.46 
                 130 
                 50 
                 0.46 
                   
               
               
                   
                   
                 0.48 
                   
                   
                   
                 DX = 0.08 
               
               
                  22 &gt; 25+ 
                   
                 0.50 
                   
                   
                   
                 (0.56 − 0.46) 
               
               
                   
                 Mode 
                 0.52 
                 115 
                 47 
                 0.52 
               
               
                   
                   
                 0.54 
                   
                   
                   
                 DX = 0.10 
               
               
                 20 &gt; 23 
                   
                 0.56 
                   
                   
                   
                 (0.64 − 0.52) 
               
               
                   
                 Mode 
                 0.58 
                 103 
                 44 
                 0.58 
               
               
                   
                   
                 0.60 
                   
                   
                   
                 DX = 0.12 
               
               
                 18 &gt; 21 
                   
                 0.62 
                   
                   
                   
                 (0.70 − 0.56) 
               
               
                   
                 Mode 
                 0.64 
                 94 
                 41 
                 0.64 
               
               
                   
                   
                 0.66 
                   
                   
                   
                 DX = 0.14 
               
               
                 16 &gt; 19 
                   
                 0.68 
                   
                   
                   
                 (0.76 − 0.60) 
               
               
                   
                 Mode 
                 0.70 
                 86 
                 38 
                 0.70 
               
               
                   
                   
                 0.72 
                   
                   
                   
                 DX = 0.16 
               
               
                 14 &gt; 17 
                   
                 0.74 
                   
                   
                   
                 (0.82 − 0.64) 
               
               
                   
                 Mode 
                 0.76 
                 79 
                 35 
                 0.76 
               
               
                   
                   
                 0.78 
                   
                   
                   
                 DX = 0.18 
               
               
                 12 &gt; 15 
                   
                 0.80 
                   
                   
                   
                 (0.88 − 0.68) 
               
               
                   
                 Mode 
                 0.82 
                 73 
                 32 
                 0.82 
               
               
                   
                   
                 0.84 
                   
                   
                   
                 DX = 0.20 
               
               
                 10 &gt; 13 
                   
                 0.86 
                   
                   
                   
                 (0.96 − 0.74) 
               
               
                   
                 Mode 
                 0.88 
                 68 
                 29 
                 0.88 
               
               
                   
                   
                 0.90 
                   
                   
                   
                 DX = 0.22 
               
               
                  8 &gt; 11 
                   
                 0.92 
                   
                   
                   
                 (1.04 − 0.80) 
               
               
                   
                 Mode 
                 0.94 
                 64 
                 26 
                 0.94 
               
               
                   
                   
                 0.96 
                   
                   
                   
                 DX = 0.24 
               
               
                 5 &gt; 9 
                   
                 0.98 
                   
                   
                   
                 (1.12 − 0.86) 
               
               
                   
                 Mode 
                 1.00 
                 60 
                 23 
                 1.00 
               
               
                   
                   
                 1.02 
                   
                   
                   
                 DX = 0.26 
               
               
                   
               
             
          
         
       
     
     In TABLE 2, ranges such as 5&gt;9 mean 5 to 9. Mode means the heart rate and 24&gt;27+ is breaths per minute. The number of heart beats in a Time Segment typically ranges from about 25 to about 300, preferably ranges from about 50 to about 200, and most preferably is about 101. 
     TABLE 2 shows a breaths per minute column. For example, if the patient&#39;s breathing cycle is detected to be in the range of 14 to 17 breaths per minutes, the pacing range would range from 0.82 seconds to 0.64 seconds, as set forth in column DX, for 101 beats. The most frequently occurring beat for this patient would be 0.76 seconds, which would occur 35 times out of 101 beats. Thus, the AMo is 35. Of course the same ratios may be applied over Time Segments having more or less than 101 Time Intervals, e.g., from about 25 to about 300 Time Intervals. 
     The breaths per minute associated with a shown group of values for the parameters of heart rate and bpm, AMo, AMo Secs and DX can be shifted up or down to account for age or to overdrive the patient&#39;s heart when required. For example, TABLE 3 shows 24&gt;27 breaths per minute associated with the following parameter values: Heart rate at mode 0.46 sec, 130 bpm, AMo=50, AMo Secs 0.46, and DX=0.08. If desired, 24-27 breaths per minute may be shifted to be associated with the parameter values which TABLE 3 shows associated with 22-25 breaths/minute, namely, Heart Rate at mode 0.52, 115 bpm, AMo=47, AMo Secs=0.52 and DX=0.10. 
     As an alternative to the natural pacing described above, software for the parameters described in FIGS. 1 a-b  and Tables 1a, 1b and 1c may be employed. If the software triggers an ALARM condition, then it triggers a vagal nerve stimulator incorporated with the implantable cardioverter defibrillator to stimulate the vagal in the expectation that the ALARM conditions predicted by the software would cease. 
     Wrist Monitor Decision Tree 
     The explanation of the wrist monitor decision tree, is contained in FIGS. 8 and 9 a-f  in which steps are identified by reference numbers. FIG. 10 shows an apparatus of the present invention which includes a wrist monitor  1921 . The patient obtains the wrist monitor, step  901  (FIG. 9 b ), the wrist monitor  1921  (FIG. 9 a ) is either connected to the patient&#39;s wrist, step  902  (FIG. 9 b ), or it is not connected step  928 , as determined by a galvanic skin sensor attached to the wrist monitor&#39;s band. When the wrist monitor  1921  is connected to the patient&#39;s wrist, step  902 , the date and time is recorded in the memory of the wrist monitor  1921 , step  901   a.  Should the patient remove the wrist monitor  1921  from his/her wrist, then the date and time is recorded in the memory of the wrist monitor  1921 , step  901   a.    
     After the connection of the wrist monitor,  1921  to the patient&#39;s wrist, step  902 , then either a pulse wave is detected, step  906 , or no pulse wave is detected, step  908 . If no pulse wave is detected, step  908 , then a prerecorded message will sound from the wrist monitor, step  921  instructing the patient to try repositioning the pulse sensor over the radial artery. If after, say five minutes no pulse is detected, then a pre-recorded message will instruct the patient to substitute a two electrode ECG waist band for the pulse sensor. 
     Finally, the wrist monitor  1921  will detect movement in the patient&#39;s arm, step  910 , or it will not detect motion, step  920 , using a strain gauge or some other piezo electric device. 
     If the wrist monitor  1921 , is connected, step  902 , and detects a pulse, step  906 , and detects movement, step  910 , and no HRV Status ALARMS, nor high ACRR ALARMS, nor MARR ALARMs, then the patient&#39;s health is acceptable, step  918  (FIG. 9 a ). 
     If the wrist monitor  1921  is connected, step  902  (FIG. 9 b ), and detects a pulse, step  906 , but does not detect movements, step  921  (FIG. 9 a ), then it is assumed the patient is comatose, step  913  (FIG. 9 b ), and a signal is sent, step  917   a,  to the patient&#39;s land line  1905 , or cellular telephone  1929 , to dial a central monitoring station, step  911  (FIG. 9 b ), the central monitoring station will call the local Emergency Medical Service (EMS), which is equipped with caller ID, and thus knows the patient&#39;s location to which they will dispatch an ambulance and transport the patient to the Emergency Room. 
     If the wrist monitor  1921 , is connected, step  902 , and does not detect a pulse, step  908 , and does not detect movement, step  916 , then it is assumed the patient is dying or dead, step  917 , and a signal is sent to the patient&#39;s land line  1905 , or cellular telephone  1929  to dial the Central monitoring station  911  (FIG. 9 b ) or the local Emergency Medical Service (EMS), which is equipped with caller ID and thus knows the patient&#39;s location to which EMS will dispatch an ambulance and transport the patient to the Emergency Room. 
     Should a patient experience an ALARM condition and wish to report it to the central monitoring station  911 , then the patient can report the ALARM condition to the central monitoring station  911 , by pushing a button on his/her wrist monitor  1921 , step  961  (FIG. 9 b ), and the date and time is recorded in the memory of the wrist monitor  1921 , step  901   a.  Should a patient want to cancel an ALARM condition reported to the central monitoring station, step  911 , then the patient can cancel the ALARM condition to the central monitoring station, step  911 , by pushing a different button on his/her wrist monitor  1921 , step  962  (FIG. 9 b ), and the date and time is recorded in the memory of the wrist monitor  1921 , step  901   a.    
     If the wrist monitor  1921  (FIG. 10) detects movement just prior to a pulse wave, step  910  (FIG. 9 a ), then that pulse wave RR is designated a MARR, Motion artifact RR, step  923  (FIG. 9 d ), and is stored in a separate bin. A bin is a term of computer art for a separate storage area. Should more than four minutes of continuous MARRs be accumulated, then the wrist monitor  1921  automatically calls the central monitoring station  911  (FIG. 9 b ), and apprizes them of the patient&#39;s excessive MARR&#39;s condition. The central monitoring station  911 , then calls the patient, step  911  (FIG. 9 e ), to try and determine the cause of the MARRs, and suggest to the patient the appropriate action. 
     If the patient is home, and the patient&#39;s land line does not have a dial tone, then the ALARM message is transmitted, by the patient&#39;s cellular telephone  1929 , step  941  (FIG. 9 f ) and pager  1931 , step  945 , to the central monitoring station, step  911  (FIG. 9 e ). As a last resort, either the patient, step  901 , or a Good Samaritan, step  917 , may rescue the patient (FIG. 9 e ). 
     Also, after movement is detected, then the sympathetic and parasympathetic parameters are measured (FIG. 9 d ). In operation, the wrist monitor  1921  separately stores ACRRs, step  920 , and MARRs, step  923 , and deletes the outliners, such that 101 NN Time Intervals remain which constitutes a Time Segment. Of course a Time Segment can be made with a different number of NN or RR Time Intervals as explained elsewhere in this specification. If an ALARM condition is detected, step  939  (FIG. 9 f ), the central monitoring station is contacted, step  911  (FIG. 9 e ) via a land line, step  943 , cell phone, step  941 , and/or pager, step  945  . A determination is also made of the consciousness, step  929 , or unconsciousness, step  915 , (FIG. 9 e ) of the patient. 
     Whether the patient is conscious, step  929 , or unconscious, step  915  (FIG. 9 e ), and an ALARM message is received by the central monitoring station, step  911 , there are five alternatives which can help get the patient to the nearest Emergency Room. The Central Monitoring Station will suggest to the conscious patient that he/she go to the nearest Emergency Room, step  971  . The Central Monitoring Station calls EMS (emergency medical services) and asks EMS to transport the patient to the nearest Emergency Room, step  972  . The central Monitoring Station calls the patient&#39;s MD. The patient&#39;s doctor calls EMS and asks EMS to transport the patient to nearest Emergency Room, step  973  . A Good Samaritan discovers the patient, step  917 , and calls EMS at  911  and asks EMS to transport the patient to the nearest Emergency Room, step  974  . The patient goes to the nearest Emergency Room, step  975  (FIG. 9 f ). 
     Recharge Base Station 
     FIG. 10 shows an embodiment of a recharge base station  1960  apparatus for the cellular telephone  1929 , wrist monitor  1921  and pager  1931  . Recharge base station  1960  is typically connected to a 110 volt, 60 cycle, AC plug  1962 , which powers the recharge base station  1960 , and which, through step down transformers, not shown, recharges the batteries of the cellular telephone  1929  and wrist monitor  1921  . Of course the base station can be designed to handle any local voltage. A stand-by battery, not shown, within the recharge base station  1960  is available to power the land line telephone  1905 , the cell phone  1929 , and/or the pager  1931 , should the AC power source be inoperative. 
     Should the wrist monitor  1921  worn by a patient, step  901 , detect an ALARM condition  939 , FIG. 9 f,  comatose condition  913 , dying or dead condition  917 , Hi/Lo HRV, ACRR  920  (FIG. 9 d ), MARR  923  (FIG. 9 d ), then the base station  1960 , will first attempt to dial out, to the central monitoring station  911  (FIG. 9 b ), on the land line telephone  1905  . 
     Hi/Lo HRV, as indicated, is calculated based on the following parameters shown in diamond shaped decision tree boxes of FIG. 9 d : SPS (step  925 ), AMo (step  927 ), DX (step  929 ), DX/M (step  931 ), Heart rate (HR) (step  933 ), Low HRV (step  935 ), and the total score ranges from +2.0 (caution)&gt;+2.5 (alarm) (step  937 ). Negative output (parasympathetic) exits to the left of the diamond shaped decision tree boxes  925 ,  927 ,  929 ,  931 ,  933 ,  935 ,  937  with negative numbers, and positive output (sympathetic) exits to the right of the boxes with positive numbers. If after about fifteen to thirty seconds contact is not established with the central monitoring station, step  911 , then the cellular telephone  1929 , will call the central monitoring station, step  911 , and report the ALARM condition. Should the cellular telephone  1929 , make contact with the central monitoring station, step  911 , then the pager  1931 , will report an ALARM condition to the central monitoring station, step  911  . When the patient is outside the home then, with the exception of the land line telephone alternative  1905 , the same protocol applies. 
     “Grab-the line” technology is installed so that if the land line hand set  1905  is being used or is off the hook, and ALARM message to the central monitoring station, step  911 , can still be transmitted. “GRAB-THE-LINE” technology is supplied by the local telephone company and is used when an emergency exists. It interrupts a busy line to convey an emergency message. 
     When an ALARM is transmitted to the central monitoring station, step  911 , the type of ALARM: comatose  913  (FIG. 9 b ), dying or dead  917  (FIG. 9 b ), Hi/Lo HRV (FIG. 9 d ), HR  933 , Lo HRV  935 , ACRR  920  (FIG. 9 d ), MARR  923  (FIG. 9 d ), is indicated to the central monitoring station, step  911 . 
     FIG. 11 schematically shows components of the wrist monitor  1921 . The wrist monitor  1921  would include one or more sensor(s)  2010  for measuring Time Intervals and other parameters described above, a microprocessor  2000  for performing calculations of the present method, memory  2020  for storing information to perform the calculations or resulting from the calculations, and a radio transmitter for communicating with the base station components such as the land line, cellular telephone or pager (or the wrist monitor could include or be hard wired to a pager). The wrist monitor  1921  could also be provided with an audible alarm. 
     EXAMPLES 
     Example 1 
     TABLE 3 shows the parameters used in Example 1 on typical patient for whom sympathetic and parasympathetic parameters were measured and compared to absolute upper and lower limits. 
     
       
         
               
               
               
             
           
               
                   
                 TABLE 3 
               
               
                   
                   
               
             
             
               
                   
                 General Preferences 
                   
               
               
                   
                 Code Version = v1.09i 
                 Min Dx = 0.01 
               
               
                   
                 Segment_size = 101 
                 Graphs/Hours = 24 
               
               
                   
                 Resolution = 0.06 
                 Auto Pause = 0 
               
               
                   
                 Cluster Min = 3 
               
               
                   
                 Baseline: 10-500 
               
               
                   
                 Outliers = 3 
               
               
                   
                 Ectopic Min-Max = 0.75 -&gt; 1.25 
               
               
                   
                 FlexType = 1 
               
               
                   
                 FlexStress = 0 
               
               
                   
                 FlexCoun = 3 
               
               
                   
                 FlexStress Count = 3 
               
               
                   
                 HRV STATUS 
                 Abs.Dx.Lo 
               
               
                   
                 Caution-Lo = −2.00 
                 Caution-Lo = 0.06 
               
               
                   
                 Caution-Hi = 2.00 
                 Caution-Tm = 10/50 
               
               
                   
                 Graph Avg = 1 pts 
                 Graph Avg = 3 pts 
               
               
                   
                 Caution-Tm = 30.00 
                 Alarm-Lo = 0.06 
               
               
                   
                 Use avg as val? yes 
                 Shunt? no 
               
               
                   
                 Alarm-Lo = −2.50 
                 Alarm-Tm = 15/50 
               
               
                   
                 Shunt? no 
               
               
                   
                 Alarm-Hi = 2.50 
               
               
                   
                 Alarm-Tm = 30.00 
               
               
                   
                 Abs.SPS.Hi 
                 Abs.Dx/Mdn.Hi 
               
               
                   
                 Caution-Hi = 48.00 
                 Caution-Hi = 0.43 
               
               
                   
                 Caution-Tm = 5/50 
                 Caution-Tm = 15/50 
               
               
                   
                 Graph Avg = 3 pts 
                 Graph Avg = 3 pts 
               
               
                   
                 Alarm-Hi = 48.00 
                 Alarm-Hi = 0.43 
               
               
                   
                 Shunt? no 
                 Shunt? no 
               
               
                   
                 Alarm-Tm = 15/50 
                 Alarm-Tm = 20/50 
               
               
                   
                 Abs.SPS.Lo 
                 Abs.Dx/Mdn.Lo 
               
               
                   
                 Caution-Lo = 4.00 
                 Caution-Lo = 0.02 
               
               
                   
                 Caution-Tm = 5/50 
                 Caution-Tm = 5/50 
               
               
                   
                 Graph Avg = 3 pts 
                 Graph Avg = 3 pts 
               
               
                   
                 Alarm-Hi = 4.00 
                 Alarm-Lo = 0.02 
               
               
                   
                 Shunt? no 
                 Shunt? no 
               
               
                   
                 Alarm-Tm = 10/50 
                 Alarm-Tm = 15/50 
               
               
                   
                 Abs.AMo.Hi 
                 ACRR 
               
               
                   
                 Caution-Hi = 90.00 
                 Caution-Lo = 0.85 
               
               
                   
                 Caution-Tm = 15/50 
                 Caution-Hi = 50.00 
               
               
                   
                 Graph Avg = 3 pts 
                 Graph Avg = 10 pts 
               
               
                   
                 Alarm-Hi = 90.00 
                 Caution-Tm = 52.00 
               
               
                   
                 Shunt? no 
                 Use avg as val? no 
               
               
                   
                 Alarm-Tm = 20/50 
                 Alarm-Lo = 0.85 
               
               
                   
                   
                 Shunt? no 
               
               
                   
                   
                 Alarm-Hi = 50.00 
               
               
                   
                   
                 Alarm-Tm = 52.00 
               
               
                   
                 Abs.AMo.Lo 
                 Low HRV 
               
               
                   
                 Caution-Lo = 10.00 
                 Caution-Lo = 45.00 
               
               
                   
                 Caution-Tm = 15/50 
                 Caution-Hi = 1.10 
               
               
                   
                 Graph Avg = 3 pts 
                 Graph Avg = 10 pts 
               
               
                   
                 Alarm-Lo = 10.00 
                 Caution-Tm = 30.00 
               
               
                   
                 Shunt? no 
                 Use avg as val? yes 
               
               
                   
                 AlarmTm = 20/50 
                 Alarm-Lo = 0.85 
               
               
                   
                   
                 Shunt? no 
               
               
                   
                   
                 Alarm-Hi = 1.10 
               
               
                   
                   
                 Alarm-Tm = 0.00 
               
               
                   
                 Abs.Dx.Hi 
                 Heart Rate 
               
               
                   
                 Caution-Hi = 0.50 
                 Caution-Lo = 45.00 
               
               
                   
                 Caution-Tm = 5/50 
                 Caution-Hi = 135.00 
               
               
                   
                 Graph Avg = 3 pts 
                 Graph Avg = 3 pts 
               
               
                   
                 Alarm-Hi = 0.50 
                 Caution-Tm = 45.00 
               
               
                   
                 Shunt? no 
                 Use avg as val? yes 
               
               
                   
                 Alarm-Tm = 10/50 
                 Alarm-Lo = 45.00 
               
               
                   
                   
                 shunt? no 
               
               
                   
                   
                 Alarm-Hi = 135.00 
               
               
                   
                   
                 Alarm-Tm = 30.00 
               
               
                   
                   
               
             
          
         
       
     
     It should be apparent that embodiments other than the above-described come within the spirit and scope of the present invention. Hence, the present invention is not limited by the above disclosure, but rather, is defined by the claims appended hereto.