if you want to beat top humans in a two-player zero-sum game, the best approach is to just approximate the Nash equilibrium because now, no matter what they're going to do, you're going to beat them. Now, I would argue that if your objectives are different, so for example, if you really want to beat up on a weak player and exploit them, then yeah, you don't want to necessarily play Nash equilibrium. You want to adapt to their weaknesses. This is challenging to do correctly, because if you try to adapt to a weak players weaknesses,