that smooth layer that's helping to protect that plaque from rupturing so that there's benefits from these agents in in many ways but we want to see the cholesterol down did a big study many years ago called the sparkle study where we took patients who'd had a stroke we put them on a high dose of this atorvastatin medicine lipitor which is a common statin 80 milligrams and many of the patients were nervous oh that's too high it's a big big dose and the other comparison was the placebo right so big dose of atorvastatin versus placebo and