major vessels and in between them is going to be the area of low flow just like if you have two sprinklers right and you turn down the pressure you're going to get a dry area in between so there are issues and like most things there there's a you know an advantage and a disadvantage you do not want blood pressure to go too low under certain circumstances and the other part of the question was that you know the timing of blood pressure medicines which is very important what you can do is a 24 hour blood pressure monitor and sometimes