our models we train with machine learning it actually matters and quite often we don't have access to data from all different sites or from all different vendors and if you every time you then go to your radiologist colleague and tell them well just annotate a few more data set and then I can do some retraining they don't really react very well to this at least in my experience okay so I want to show you three different applications for where we at the moment use deep learning and we're actually has had significant impact really