to the macroscopic level this type of multi scale imaging can be very very important because in current medical practice or biomedical practice for cells and below we use optical microscopy so we're acquiring optical contrast but for tissues and above we switched to now optics we're gonna use MRI ultrasound x-ray CT what have you so we're talking about two different contrast mechanisms mechanisms preventing us from correlating images across all the lens skills as we know to understand about the problem we have to have a multiscale