Sigma and these organs you can quantify biomarkers for example measure a tumor volume and then sort of if you come to the more higher level of the more we're actually probably highest added value is sort of computer-aided interpretation and diagnosis there are probably very few applications at the moment really being used and probably the only one I can really think of where actually machine learning has had an impact at those high level features is at the moment in for example mammography screenings so there are some systems