fit into a nice pattern except there's a missing one yes and the methodology of saying well we should search for that missing one because of all these symmetries it must be there that works and the question is why does and why does it work so it's not clear that works in biology so when I was a postdoc in San Diego I got to know Francis Crick who who was just become very interested in the brain he was a very impressive thinker but he was of the opinion that the idea that the elegant thing is going to be true did not necessarily apply to