of penetration for this type of imaging so this is going to extend the capability of fluorescent proteins and some of the derivatives this technology is being tested at Washington University for a human studies for human applications and this is one example where a breast tumor was imaged using standard ultrasound imaging and photoacoustic imaging we can see the CM tumor using a very safe light dose the laser intensity is one-half of the safety limit and a safety light safety limit is less than one-tenth of the dams threshold so this is