assume that at test time we don't have one of sequences available so we have to use another imaging sequence and if you don't do then the main invariant features you see you end up with horrible results in your in your segmentation where you're supposed to to spot a brain tumor which you can probably see here quite nicely and here when you have done the domain adaptation even if you switch one sequence to another you actually do quite well good so the last two minutes I just want to talk about some challenges which we have