for other uses see aaa (disambiguation)  aaa or aaa+ is an abbreviation for atpases associated with diverse cellular activities. they share a common conserved module of approximately 230 amino acid residues. this is a large, functionally diverse protein family belonging to the aaa+ superfamily of ring-shaped p-loop ntpases, which exert their activity through the energy-dependent remodeling or translocation of macromolecules. aaa proteins couple chemical energy provided by atp hydrolysis to conformational changes which are transduced into mechanical force exerted on a macromolecular substrate. aaa proteins are functionally and organizationally diverse, and vary in activity, stability, and mechanism.{{cite journal |author=erzberger jp, berger jm |title=evolutionary relationships and structural mechanisms of aaa+ proteins |journal=annu. rev. biophys. biomol. struct. |volume=35 |pages=93-114 |year=2006 |pmid=16
Protein_domains Protein_families Single-pass_transmembrane_proteins