 u.s. route 176 (us 176) is a spur of us 76 in the u.s. states of north carolina and south carolina. the u.s. highway runs  from us 25 business and north carolina highway 225 (nc 225) in hendersonville, north carolina, east to us 52 in goose creek, south carolina. us 176 serves the transition region between the blue ridge mountains and foothills of western north carolina and the upstate, midlands, and lowcountry regions of south carolina. the highway passes through and connects spartanburg, one of two major cities in the upstate, and columbia, the south carolina [[state capital
Three-digit_U.S._Highways Transportation_in_Berkeley_County,_South_Carolina Transportation_in_Calhoun_County,_South_Carolina Transportation_in_Greenville_County,_South_Carolina Transportation_in_Henderson_County,_North_Carolina Transportation_in_Lexington_County,_South_Carolina Transportation_in_Newberry_County,_South_Carolina Transportation_in_Orangeburg_County,_South_Carolina Transportation_in_Polk_County,_North_Carolina Transportation_in_Richland_County,_South_Carolina Transportation_in_Spartanburg_County,_South_Carolina Transportation_in_Union_County,_South_Carolina U.S._Highways_in_North_Carolina U.S._Highways_in_South_Carolina U.S._Route_76