  columbus city is a city in louisa county, iowa, united states. the population was 391 at the 2010 census. it is part of the muscatine micropolitan statistical area. ==history== columbus city was platted in the 1840s. ==geography== columbus city is located at  (41.258225, -91.375711).{{cite web|url=http://www.census.gov/geo/www/gazetteer/gazette.html|publisher=[[united 
Cities_in_Iowa Cities_in_Louisa_County,_Iowa Muscatine,_Iowa_micropolitan_area