 doxapram hydrochloride (marketed as dopram, stimulex or respiram) is a respiratory stimulant. administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate. ==mechanism of action== thumb|alt=photograph of a vial of doxapram|a vial of doxapram doxapram stimulates chemoreceptors in the carotid bodies of the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem. ==appearance== doxapram is a white to off-white, odorless, crystalline powder that is stable in light and air. it is soluble in water, sparingly soluble in alcohol and practically insoluble in ether. injectable products have a ph from 3.5-5. benzyl alcohol or chlorobutanol is added as a preservative agent in the commercially available injections. ==uses== doxapram is used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. it may be useful for treating respiratory depression in patients who have taken excessive doses of drugs such as buprenorphine which may fail to respond adequately to treatment with naloxone.buprenorphine drug data sheet it is equally effective as pethidine in suppressing shivering after surgery.{{cite journal | last1 = singh | first1 = p | last2 = dimitriou | first2 = v | last3 = mahajan | first3 = rp | last4 = crossley | first4 = aw | title = d
Morpholines Pyrrolidones Respiratory_agents