 itraconazole (r51211), invented in 1984, is a triazole antifungal agent prescribed to patients with fungal infections. the drug may be given orally or intravenously. == medical uses == itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). in particular, it is active against aspergillus, which fluconazole is not. it is also licensed for use in blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis. itraconazole is over 99% protein-bound and has virtually no penetration into cerebrospinal fluid. therefore, it should never be used to treat meningitis or ot
Belgian_inventions Dioxolanes Janssen_Pharmaceutica Lactams Organochlorides Phenol_ethers Piperazines Triazole_antifungals