   inositol trisphosphate receptor (insp3r) is a membrane glycoprotein complex acting as a ca2+ channel activated by inositol trisphosphate (insp3). insp3r is very diverse among organisms, and is necessary for the control of cellular and physiological processes including cell division, cell proliferation, apoptosis, fertilization, development, behavior, learning and memory. inositol triphosphate receptor represents a dominant second messenger leading to the release of ca2+ from intracellular store sites. there is strong evidence suggesting that the insp3r plays an important role in the conversion of external stimuli to intracellular ca2+ signals characterized by complex patterns relative to both space and time. for example, ca2+ waves and oscillations. the insp3 receptor was first purified from rat cerebellum by neuroscientists surachai supattapone and solomon snyde
Genes_on_chromosome_12 Genes_on_chromosome_3 Genes_on_chromosome_6 Inositol Signal_transduction Transmembrane_receptors