Judul: Aktivitas hepatoproteksi Ekstrak Polifenol Buah Delima (Punica granatum L.) Terhadap Tikus Putih yang Diinduksi Parasetamol
Abstrak: The patient of liver disease more increase. Pomegranate has been higher antioxidant activities and reported as hepatoprotection. The research to make for activity pomegranate polifenol as hepatoprotector and influence in liver histopathology of rat to induction by paracetamol. Polyphenol extracted by mixture solvent acetone:water:acetid acid (90:9.5:0.5). There are 22 rats randomly divided into 7 following group, they are group I allowed fed with strandard pellet, group II allowed fed with strandard pellet and paracetamol 500 mg/kg BB, group III allowed fed with strandard pellet, paracetamol 500 mg.kg BB, and cursil-70 13.3 mg/kg BB, group IV, V, VI, and VII allowed fed with strandard pellet, paracetamol 500 mg/kg BB, and extract polyphenol of pomegranate with doses 13.3 mg/kg BB, 100 mg/kg BB, 250 mg/kg BB, and 500 mg/kg BB for severally group. Experiment was conducted for 34 days and at the last day, observed liver histopathology about number of necrotic cells, apoptosis cells, kupfer cells, and fatty degeneration. Polyphenol extract of pomegranate with dose 500 mg/kg BB to point out possible chase destruction of liver (p<0.05) because number of necrotic cells is low, nothing apoptosis cells, number of kupfer cells is low, and fatty degeneration is low
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Judul: Aktivitas Fraksi Polifenol Buah Delima (Punica granatum L.) terhadap Peroksidasi Lipid Darah Tikus yang Diinduksi Parasetamol
Abstrak: Pomegranate (Punica granatum L.) has been reported to have the higher antioxidant activities than other medicinal plants. The aim of this study was to investigate polyphenol fraction activities from pulp pomegranate against blood lipid peroxidation (TBARS) in rats induced by paracetamol. Twenty two rats were divided into 7 groups. One normal group induced aquades and six treatment groups induced paracetamol (500 mg/KgBW) during 34 days. Positive control group of treatment induced Cursil®70 (13.3 mg/KgBW), and another groups induced polyphenol fraction doses 13.3 mg/KgBW, 100 mg/KgBW, 250 mg/KgBW, and 500 mg/KgBW, respectively. Polyphenol were extracted by acetone:water:acetic acid (90:9.5:0.5). TBARS was reacted by thiobarbituric acid (TBA) 1% and analysed by spectrophotometer in λ=532 nm. Polyphenol yields have got 36.2%. Paracetamol inductions as long as 34th days increased TBARS levels 120.66%. The PC and FD13.3 decreased TBARS 8.14% and 10.45% not significantly (p=0.548). FD100, FD250, and FD500 decreased TBARS 18.18%, 33.23%, and 41.84% (p<0.05), respectively.
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Judul: Metrik Einstein (Anti-) Self-Dual Berdimensi Empat dengan Metode Cartan
Abstrak: Gravitational field equation can be formulated in differential forms (differential geometry), which describes gravity as a manifestation of the curvature of space-time. Curvature of space-time is characterized by a metric that satisfies the gravitational field equation. With differential forms it can be formulated the (anti-) self-dual Einstein equation, which is a modification of the Cartan structure in (anti-) self-dual basis. Calculation of (anti-) self-dual metric with (anti-) self-dual Einstein equation is simpler than the calculation using Christoffel symbols.
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