Judul: Pengaruh Lempuyang Gajah (Zingeber zerumbat L.) dan Fraksi Ekstraknya terhadap Kadar Kolestelor, Trigliserida dan Glukosa Darah dan Hati Tikus Sprague Dawley
Abstrak: Lempuyang gajah (Zingiber zerumbet L.) adalah salah satu dari tumbuhan obat tradisional yang sering digunakan sebagai obat luar maupun dalam, disamping sebagai makanan lalapan dan bumbu masakan. Komponen kimia utama yang dikandungnya antara lain minyak atsiri yang terdiri dari senyawa zerumbon, a-pinen, a-kariofilen, kamfer dan sineol. Penelitian ini bertujuan untuk mempelajari pengaruh aktifitas lempuyang gajah dalam bentuk tepung, ekstrak steam distillation, ekstrak etanol 95% dan jamu terhadap kadar kolesterol, trigliserida dan glukosa darah dan hati tikus. Selain itu juga dipelajari sifat fisiko kimia ekstrak lempuyang gajah yang diperoleh dari teknik steam distillation dan ekstraksi dengan pelarut etanol 95%.
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Judul: Potensi Teh Herbal Lempuyang Gajah (Zingiber zerumbet L.) sebagai Antioksidan pada Tikus Sprague-Dawley Hiperkolesterolemia
Abstrak: Hypercholesterolemic conditions can increase lipid peroxidation and as an indicator of the presence of free radicals in the body. This research aimed to determine the efficacy of lempuyang gajah (Zingiber zerumbet L.) herbal tea as an antioxidant to prevent lipid peroxidation in hypercholesterolemic rats. Twenty six rats were divided into 4 following groups: normal, hypercholesterolemia, extract 1 (low dose), and extract 2 (high dose) groups. Hypercholesterolemia were induced in rats by high cholesterol diet (1.5% cholesterol) and oral administration of propil tiourasil (PTU) 0.5 mg/kg bw in six weeks. Before necropsied, rats were given standard diet for the last four weeks. Lipid peroxide concentrations in the liver were analyzed using thiobarbituric acid (TBA) assay with spectrofotometer UVVis at 532 nm. Results showed that feeding cholesterol free diet in the last four weeks normalized liver lipid peroxide concentration in the three treatment groups. The average of all groups were 40.88±13 nmol/g (p=0.317). Addition of extract reduced correlation between liver lipid peroxide concentration and blood cholesterol concentration on the extract groups (1 and 2). This observation suggest that components of lempuyang gajah herbal tea can prevent lipid peroxidation in liver.
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Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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