Judul: IPB (Bogor Agricultural University)
Abstrak: Hypercholesterolemia and LDL oxidation are the major factors of atherosclerosis. The ethanol extract of the ginger (EEG) and Zn each posses effect reduce cholesterol and antioxidant. These research combined EEG and Zn as antihypercholesterolemia and antioxidant to prevent atheroma in New Zealand white fed rabbits atherogenic diet and hypercholesterolemia rabbits. Twenty eight male rabbits were divided into seven groups. For 6 weeks, group 1 was fed with a normal diet and group 3 was fed with an atherogenic diet. Beside the atherogenic diet, group 2,4,5,6, and 7 were also treated by supplementary treatment. Second phase research, 24 male hypercholesterolemia rabbits were divided into 6 groups. For 6 weeks, group 1 was fed with a normal diet. Fed rabbits atherogenic diet group 2,4,5,6, and 7 and hypercholesterolemia rabbits group 2,3,4,5, and 6 were treated by supplementary treatment, which are Zn 6.67 mg/kg, EEG 200 mg/kg, combination EEG 50 mg/kg and Zn 6.67 mg/kg, combination EEG 100 mg/kg and Zn 6.67 mg/kg, and atorvastatin (positive control) 1.9 mg/kb BW per day. Combination EEG 50 mg/kg and Zn 6.67 mg/kg and combination EEG 100 mg/kg and Zn 6.67 mg/kg treatment impeded the increase of total cholesterol, LDL, and prevent atheroma equal to the positive control. Based on the ability to restrain the increase of MDA (lipid peroxidation) in fed rabbits atherogenic diet the treatment with combination EEG 50 mg/kg and Zn 6.67 mg/kg resulted higher than positive control or the other treatment. Based on reduced plaque atheroma in hypercholesterolemia rabbits, combination EEG 50 mg/kg and Zn 6.67 mg/ kg treatment also the best result. These researches concluded that combination EEG 50 mg/kg and Zn 6.67 mg/kg BW per day treatment exhibited the highest atheroma prevention effect in fed rabbits atherogenic diet or hypercholesterolemia rabbits as compared to the positive control or the other treatments.
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Judul: Lipid Peroxide Concentration in The Liver of Hyperlipidemic Rabbits Treated by Hypolipidemic Substance.
Abstrak: Degenerative disease has caused the highest mortality in the world. The disease may occur due to our life style which prefer fast food than traditional one and overeating resulted in hyperlipidemic. This condition will increase lipid peroxidation caused by free radicals in the body such as in the liver. The objective of this research is to determine the influence of hypolipidemic substance on lipid peroxide in the liver of hyperlipidemic rabbits. Twenty four male New Zealand White rabbits were divided into four group: group I (normal), group II (Hyperlipidemic), group III (mixture of Jati Belanda), and group IV (lovastatin). Lipid peroxide concentration was measured by TBA (thiobarbiturit acid) assay that measure malondyaldehida (MDA) as product of lipid peroxidation using spectrophotometer at λ = 532 nm (Yagi et al 1994). The result of the research showed that feeding rabbits with chow contains 0.5% cholesterol and 5% of palm oil caused hyperlipidemic. Lipid peroxide concentration of rabbit’s liver in group II increased two times compared with group I. Group III and IV had lower lipid peroxide concentration of rabbit’s liver compared with group II which is 58.83% and 49.06%. This data showed that Jati Belanda leave mixture and lovastatin decreased lipid peroxidation in the liver.
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Judul: Karakter Lanskap Lokal pada Pantun Adat Minangkabau
Abstrak: Minangkabau adalah salah satu kebudayaan tertua dan terbesar di Indonesia. Minangkabau dikenal oleh keunikan dan ciri khasnya sendiri dari abad ke abad. Keunikan dan ciri khas itu tidak hanya melekat pada budaya, tapi juga melekat pada aspek lainnya seperti warisan budaya, peninggalan sejarah, budaya tradisional, hingga karakter lanskapnya. Salah satu warisan budaya terkenal Minangkabau adalah Pantun. Pantun adalah warisan budaya Minangkabau yang paling dekat kaitannya dengan kehidupan sehari-hari masyarakat Minangkabau. Pantun biasanya digunakan sebagai pelengkap atau tambahan pada percakapan harian, sebagai pembuka atau sambutan pada acara adat, atau sebagai pepatah dan peribahasa yang digunakan sehari-hari. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis bacaan pantun adat Minangkabau yang menunjukkan karakter lanskap lokal Minangkabau. Penelitian ini menggunakan metode deskriptif dengan melakukan analisis dan studi literatur melalui wawancara dan observasi lapang. Keberagaman elemen lanskap baik dari segi elemen fitur alami maupun elemen fitur buatan yang terkandung di dalam pantun adat Minangkabau mencerminkan kekayaan karakter lanskap Minangkabau itu sendiri. Fitur alami dan buatan yang ada dalam pantun mempunyai bobot yang relatif sama atau seimbang. Fitur alami yang paling dominan dalam pantun adalah landform, khususnya elemen gunung. Fitur buatan yang paling dominan adalah elemen pemukiman, khususnya elemen pasar. Karakter kunci lanskap Minangkabau adalah gunung Marapi, gunung Singgalang, danau Singkarak, danau Maninjau, dan bukit Barisan. Karakter lanskap Minangkabau memperlihatkan lanskap pemukiman yang berada di tengah elemen-elemen pembentuk lanskap yang luas seperti gunung, lautan, sawah atau ladang, dan sungai. Keberadaan elemen lanskap yang terdapat pada pantun Adat Minangkabau baik pantun lama maupun pantun baru masih terjaga kelestariannya. Keberadaan fitur lanskap pada pantun adat Minangkabau merupakan adaptasi lingkungan sekitar oleh sastrawan Minangkabau yang dituangkan kedalam karya seni berbentuk literatur.
Keyword: lanskap budaya, lanskap tradisional, taman vernakular, rumah gadang, lanskap minangkabau, pantun adat