Judul: Sitotoksisitas Ekstrak Kulit Kayu Pinus merkusii Jungh. et de Vriese terhadap Sel Kanker Serviks HeLa
Abstrak: Cervical cancer is the most common death cause of cancer in Indonesian women. One of the efforts of cancer treatment is the utilization of natural materials compounds. Some plants have potential as anticancer, one of them is bark of Pinus merkusii. The purpose of this study was to determine the cytotoxic activity of Pinus merkusii bark extract against HeLa cells by microculture tetrazolium technique (MTT) assay. The study also tested the phytochemical content and the initial screening of cytotoxicity with Artemia salina. The Highest yield of 70% ethanol P. merkusii bark extract was 6.30%. Pinus merkusii contains flavonoids, triterpenoids, saponins and tannins. The results of cytotoxicity assay using A. salina showed that the Pinus merkusii bark extract has activity and potential as anticancer indicated by its LC50 values < 1000 μg/mL. The 70% ethanol extract of P. merkusii bark has highest cytotoxic activity against HeLa cells with IC50 value of 266.01 μg/mL which was higher than methanol, water, and aceton extract with IC50 values for respectively 408.13 μg/mL, 433.51 μg/mL, dan 880.24 μg/mL.
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Judul: Potensi Antikanker Ekstrak Daun Sirih Merah (Piper crocatum) terhadap Sel HeLa
Abstrak: Cervical cancer is the most common death cause of cancer in Indonesian after human breast cancer. One of the efforts of cancer treatment is the utilization of natural materials compounds. Some plants have potential as anticancer for example leaves of Piper crocatum. Base of previous study methanol extract Piper crocatum has IC50 values 44.25 μg/mL on breast cancer cells (T47D). The purpose of this study was to determine inhibition activity of Piper crocatum ethanol, waters extract and Piper crocatum leaves powder against HeLa and Chang cells by Microculture Tetrazolium Technique (MTT) assay. The result showed that Piper crocatum leaves powder has higher inhibition with value 86% at 800 ppm which was higher than water and ethanol 30% with % inhibition 46% at 800ppm and 39% at 400 ppm.
Keyword: Piper crocatum, HeLa cells lines, MTT, inhibition, cervical cancer

Judul: Osilasi regular dan chaotic pada sistem bandul yang diputar
Abstrak: Telah dipelajari perilaku sistem bandul yang diputar. Sistem ini memperlihatkan transisi dari osilasi regular ke osilasi chaotic melalui serangkaian penggandaan periode driving force. Parameter kontrol yang digunakan adalah amplitudo driving force (F) yang dinaikkan secara bertahap sebesar 0.001 N. Pada nilai 1 = 0.7 N terbentuk satu putaran pada ruang fasa, pada F = 0.75N terbentuk dua putaran, pada F = 0.775N terbentuk empat putaran, dan pada F = 0.782 N terbentuk delapan putaran. Pada saat nilai F diperbesar kembali, osilasi sistem berubah dari osilasi regular ke osilasi chaotic. Ketika keadaan chaotic tercapai, gerakan sistem sangat tidak beraturan dan sulit diprediksikan. Pada keadaan chaotic, perbedaan sangat kecil pada penentuan dua nilai sudut awal (1° dan 1.00001°) akan menghasilkan dua perilaku akhir sistem yang jauh berbeda. Selanjutnya ketika selang amplitudo driving force diperbesar (dari F = 0.735 N sampai dengan F = 0.806N ) gerakan sistem menampilkan perilaku keteraturan, dimana dihasilkan pola geometri yang teratur dan tersusun, kemudian ketika jangkauan amplitudo driving force diperbesar lagi (dari F = 0.65N sampai dengan F = 1.895N ) serangkaian gerakan periodik dan chaotic bergantian secara berulang.
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