Judul: Desain Lanskap Terminal Bubulak Berbasis Ecological Landscape di Bubulak, Kota Bogor, Jawa Barat
Abstrak: Terminal Bubulak merupakan salah satu terminal yang ada di Kota Bogor yang berfungsi sebagai pengatur kedatangan dan keberangkatan angkutan umum serta sebagai sarana untuk mobilisasi masyarakat. Kondisi Terminal Bubulak saat ini belum memenuhi standar terminal tipe b karena belum tersedia fasilitas yang memadai. Selain itu kondisi perkerasan yang rusak mengakibatkan terjadinya banyak genangan di beberapa titik, tempat pembuangan sampah yang berada di dekat area penerimaan. Secara ekologis kondisi ini menyebabkan terganggunya aktivitas yang ada pada tapak sehingga harus segera ditanggulangi, maka perlu dilakukan penelitian desain Terminal Bubulak berbasis ecological landscape melalui penerapan yang mencakup stormwater green infrastructure, penanaman tanaman yang beragam, pemilahan sampah, material yang ramah lingkungan dan trotoar yang mempunyai roof top yang berfungsi memperbaiki iklim mikro bagi tapak dan lingkungan sekitarnya. Penelitian ini bertujuan untuk mendesain Terminal Bubulak berbasis Ecological Landscape. Penelitian dilakukan dengan metode survei lapangan dan studio desain dengan tahapan pengerjaan yaitu ; riset dan analisis, perancangan, dan gambar konstruksi. Konsep dasar dari tapak penelitian ini adalah “Eco-Public Terminal” yang didasarkan pada lanskap ekologis untuk memenuhi dan meningkatkan kualitas hidup masyarakat, perancangan tersebut memperhatikan persepsi dan preferensi pengguna serta potensi dan permasalahan yang ada di tapak. Penelitian ini berfokus pada penyediaan fasilitas dan utilitas yang lengkap untuk terminal tipe b. Strategi penerapan konsep tersebut melalui peningkatan fungsi ekologis, peningkatan fungsi estetika, peningkatan fungsi sosial, dan pemenuhan kebutuhan fasilitas terminal bagi pengguna. Konsep desain yang diaplikasikan pada lanskap terminal Bubulak mengimplementasikan bentuk dari senjata tradisional Jawa Barat yaitu Kujang yang merupakan ikon Kota Bogor, kemudian dikembangkan dalam pembagian area-area yaitu area kedatangan, area parkir, area kantor, area service, dan area inti. Hasil penelitian ini berupa site plan, detail engineering design, gambar potongan, ilustrasi perspektif, dan animasi.
Keyword: Landscape Terminal, Terminal Type B, Infrastructure of Land Transportation, Green Open Space

Judul: Perencanaan Lanskap Terminal Baranangsiang sebagai Upaya Revitalisasi Terminal Tipe A di Kota Bogor
Abstrak: Terminal as node in the transport network plays an important role to regulate the movement of passengers or goods safely, orderly, conveniently, and efficiently in terms of time and cost. Bogor Baranangsiang Terminal (TBB) that has been serving needs of public transport users currently in disorganized and overload conditions. It is often a source of traffic congestion for the the surrounding area. The method used in this study followed the design process found by Gold which includes preparation, inventory, analysis, synthesis and planning by identifying the physical, biophysical, technical and social, and legal aspects. This study produces a landscape plan and a description plan of the TBB includes space planning, facilities and activities, circulations, greenery, and carrying capacity area. Those are obtained through descriptional and spatial analysis. The basic concept of this plan is Convenience and Care Terminal (Terminal C2). The development of the concept is done by adding 5 355.6 m2 (24.3%) area so that the total area be 27 455.6 m2 (± 2.74 ha).
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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