Judul: Peran Serta Sektor Informal Kepariwisataan di Selabintana dalam Memperluas Kesempatan Kerja di Pedesaan (Studi Kasus di Desa Sudajayagirang, Kec. Sukabumi, Kabupaten Sukabumi, Jawa Barat)
Abstrak: Sejalan dengan sifat kepariwisataan itu, sektor ini formal kepariwisataan di Selabintana juga bersifat musiman, berfluktiasi sesuai dengan fluktuasi wisatawan yang datang. Pola pemilihan kegiatan sektor informal kepariwisataan bervariasi untuk tiap dusun. Pedagangan baso, pedagang asongan, pedagang tanaman hias, tukang foto dan pedagangjagung rebus didominasi oleh pekerja dari dusun Selabintana Kulon.
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Judul: Pengaruh parawisata terhadap peluang berusaha dan bekerja di sektor informal : Kasus di desa Bandungan, Kecamatan Ambarawa, Kabupaten Semarang, Jawa Tengah
Abstrak: Penelitian ini bertujuan untuk menelaah beragam usaha dissektor informal yang muncul akibat adanya kegiatan kepariwisataan. Selain itu ditelaah pula pola perilaku masyarakat setempat dalam hal pencarian nafkah. Lebih lanjut penelitian ini juga berusaha menelaah bagaimana struktur sosial masyarakat yang bersangkutan sehubungan dengan berkembangnya obyek pariwisata tersebut. Pola-pola hubungan yang dilihat adalah dalam kelembagaan usahatani dan sistem pelapisan sosial. Laporan ini merupakan hasil penelitian di daerah wisata Desa Bandungan. Informasi dan data diperoleh dari responden maupun informan. Responden adalah pekerja sektor informal dari berbagai jenis usaha, baik sebagai mata pencaharian pokok maupun sambilan. Selama penelitian telah diwawancarai 30 orang responden dan 8 orang informan. ...
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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