Judul: Relationship of Spatial between Topography and  Soil Characteristics of Classification Differentiae in Quaternary Volcanic Hills in  Subang, West Java
Abstrak: Penarikan batas satuan peta tanah (SPT) untuk daerah dengan keragaman topografi yang tinggi dapat didasarkan pada perbedaan topografinya. Namun banyak kasus menunjukkan fakta bahwa di dalam satuan topografi yang sama masih dijumpai keragaman karakteristik tanah yang tinggi. Penelitian ini dirancang untuk mengamati morfologi tanah dengan intensitas tinggi pada area sempit yang memiliki faktor pembentuk tanah homogen kecuali topografi, di perbukitan volkan kuarter di Subang, Jawa Barat. Penelitian ini dimaksudkan untuk mengungkapkan apakah keragaman spasial topografi, khususnya di daerah dengan tipologi seperti area studi, sejalan dengan keragaman karakteristik tanahnya. Hasil penelitian diharapkan dapat dijadikan dasar dalam menentukan strategi pengamatan dan penarikan batas untuk pemetaan tanah khususnya tingkat detil. Penelitian dilaksanakan pada area seluas 10 ha yang merupakan bagian dari PT. Perkebunan Buah Subang dengan melakukan 50 pemboran (boring) secara menyebar menurut segmen lereng dan pengamatan 6 (enam) profil pewakil. Didasarkan pada karakteristik morfologinya ke-6 (enam) profil pewakil telah diklasifikasikan menurut dua sistem klasifikasi. Hasil klasifikasi hingga Subgroup menurut Taksonomi Tanah menunjukkan bahwa ke-6 (enam) profil pewakil merupakan Typic Dystrudepts, yang berarti bahwa seluruh area studi hanya terdiri dari Typic Dystrudepts. Sementara itu hasil klasifikasi hingga kategori Macam Tanah menurut Sistem Klasifikasi Nasional menunjukkan area studi didominasi Latosol Kromik dan sebagian kecil tanahnya termasuk Latosol Haplik. Penelusuran lebih seksama menunjukkan masih ada keragaman morfologi di antara ke-6 (enam) profil yang dideskripsi, terlepas dari hasil klasifikasi yang homogen. Keragaman morfologi yang tergolong menonjol adalah warna tanah, yaitu 3 (tiga) profil memiliki hue 7.5YR, dan 2 (dua) profil memiliki hue 5YR, dan 1 (satu) profil memiliki hue 10YR. Keragaman lainnya antara lain ketebalan horizon genetik dan diagnostik. Namun demikian, hasil penelusuran hubungan antara posisi profil pewakil pada segmen lereng dengan keragaman morfologi tersebut menunjukkan hubungan yang tidak konsisten, yaitu hue dominan 7.5YR atau 5YR atau 10YR dan atau ketebalan horizon genetik dan diagnostik tertentu dari tanah di daerah studi tidak bersifat unik untuk profil pada segmen lereng tertentu., The delination of soil map unit (SMU) boundaries for areas with high topographical variability can be based on the topographic boundaries. However, many cases show the fact that in the same topographic unit there is still a high variability of soil characteristics. This study was designed to intensively observe soil morphology in a small area that has homogeneous soil forming factors except topography, in the quarternary volcanic hills in Subang, West Java. This study is intended to reveal whether the spatial variability of topography, especially in areas with a typology such as the study area, is in line with the variability of soil characteristics. The results of the research are expected to be used as a basis for determining the strategy of soil observation and SMU delineation, especially for the detailed mapping. The research was carried out in an area of 10 ha which is part of PT. Buah Subang by carrying out 50 augers spread according to the slope segment and observing six representative profiles. Based on their morphological characteristics, the six representative profiles have been classified according to two classification systems. The results of the classification to Subgroups according to Soil Taxonomy show that the six
Keyword: morfologi tanah pembeda, pemetaan tanah detil, satuan peta tanah

Judul: Studi Pemetaan Tanah Dengan Menggunakanarealkuncidlkecamatan Ciomas Dan Padarincang Kabupaten Serang, Banten
Abstrak: As natural and dinamic heterogcncous product, soil character are different from one place to another, following the variation factors of soil formation. The accurate soil mapping are needed (0 support regional planning. Study of soil mapping by using key area in Subdistrict of Ciomas and Padarincang of Serang Regency have been done.• The objective of this study are: to learn variation, characteristics, classification and delineation the soil mapping unit in the key area, to explore the soil mapping unit from the key area to entire survey area. That data are compared with data from Team of FEM IPB survey result (Team ofFEM IPB, 2003), that using combination ofLandlorm and Grid System methodes. Determination of key area was conducted at representatif area based on landform analyse from topographic and geological maps. At the key area, field observation of soil characteristic, and classification with Soil Taxonomy (Soil Survey Staff, 1996 and 1999). Was done the observation also for land characteristics. Therefore, design of soil mapping unit covered in the key area and factor that determine delineation of soil mapping unit, could be learned. Extrapolation to entire survey area due to relation of soil mapping unit at the key area with consideration of the landform. Survey area covered 15.365 Ha and the wide of key area 1.482 Ha. Soil subgroup in the key area are Typic Hapludults, Typic Dystrudepts, Lithic Eutrudox, Typic Kandiudox, Typic Endoaqualfs, Typic Hydraquents, Sulfic Tropaquepts and Lithic Troporthents. Soil subgroups based on FEM IPB Team are Thapto-Histic Fluvaquents, Aeric Tropic Fluvaquents, Tropic Fluvaquents, Thapto-Histic Tropic Fluvaquents, Typic Hydraquents, Typic Kandiudox, Aquic Kandiudox, Typic Hapludults and Lithic Tropaquepts. The survey area with volcanic slope landforms, that covered SPT 1, 2, 3, 4, and SPT 5, were found 6 subgroup of soil, while in mapping that done by Team FEM IPB, that covered SPT 4, 6, 7, 8, 9 and SPT 10, were found 7 soil subgroup. Of the closed depression landform (SPT 6 and 7) there were 3 soil subgroups, but according to the FEM IPB Team that covered SPT 1,2,3 and SPT 5 consist 5 soil subgroups. Mapping by using key area produce more accurate soil mapping unit at volcanic slope landforms, but less covering all soil varieties at flat area of closed depression landform. Grid system are better to do in flat survey area.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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