Judul: Perancangan dan Implementasi Container dengan Konsep Swarm dan Metode Ingress Load Balancing Menggunakan Docker
Abstrak: Masjid Alumni IPB ingin mengembangkan suatu sistem yang disebut masjid berbagi. Masjid berbagi merupakan suatu sistem berbasis aplikasi web dan mobile dan terhubung ke cloud. Masjid berbagi dibuat untuk pengelolaan dan berbagi informasi tentang kegiatan masjid-masjid. Semua aplikasi dan informasi disimpan pada server masjid berbagi sehingga server masjid berbagi harus dapat melayani permintaan oleh masjid-masjid. Pada penelitian ini bertujuan untuk perancangan dan implementasi container menggunakan docker dengan menerapkan docker swarm dan load balancing ingress. Penelitian ini dibagi kedalam empat tahap utama yaitu komunikasi (analisis lingkungan), penerapan container, pengujian dan analisis. Pada penelitian dilakukan perbandingan penerapan dengan satu sampai lima container untuk mengetahui pengaruh banyak container dengan respon server, request yang dapat dilayani dan throughput. Hasil penelitian menunjukkan semakin banyak container lebih baik daripada hanya menggunakan satu container karena dapat meningkatkan respon time dan banyak sucess request. Tetapi banyaknya container harus tetap diperhatikan.
Keyword: Docker, Container, Ingress load balancing, Docker swarm

Judul: Container Management System REST API Development for NVIDIA DGX A100 Server
Abstrak: Server NVIDIA DGX A100 memiliki konfigurasi yang tidak mudah untuk digunakan oleh peneliti. Penggunaan container pada server dapat memudahkan pengguna baik dari sisi peneliti maupun admin. Selain itu, container memiliki kelebihan pada sisi keamanan, yaitu kegagalan container pengguna tidak berdampak pada kegagalan sistem secara keseluruhan. Sampai saat ini, belum ada sistem manajemen pada server tersebut yang dapat menyesuaikan kebutuhan dan memberikan kemudahan pengguna. Penelitian ini bertujuan untuk mengimplementasikan REST API sistem manajemen container pada server NVIDIA DGX A100 di Institut Pertanian Bogor (IPB). Metode yang digunakan adalah prototyping dengan dua iterasi. Terdapat empat tahap pada metode ini, yaitu komunikasi, perencanaan cepat dan pemodelan rancangan cepat, konstruksi prototipe, serta penyebaran, pengiriman, dan umpan balik. Hasil penelitian ini adalah REST API sistem manajemen container yang menjamin isolasi antar pengguna, keamanan server, dan efisiensi pengelolaan container. Pengujian REST API menggunakan black box testing dengan empat skenario. Hasil pengujian menunjukkan keberhasilan implementasi pada semua endpoint berdasarkan setiap skenario yang ada antara hasil dan masukan sudah sesuai seperti yang diharapkan. Penelitian ini juga dapat dijadikan acuan untuk pengembangan sistem manajemen container pada jenis HPC lainnya., The NVIDIA DGX A100 server has a configuration that is not easy for researchers to use. The use of containers on the server can make it easier for users both from the researcher and admin side. In addition, containers have advantages in terms of security, namely the failure of the user container does not have an impact on the failure of the system as a whole. Until now, there has been no management system on the server that can customize the needs and provide user convenience. This research aims to implement REST API container management system on NVIDIA DGX A100 server at Bogor Agricultural University (IPB). The method used is prototyping with two iterations. There are four stages in this method, namely communication, rapid planning and rapid design modeling, prototype construction, and deployment, delivery, and feedback. The result of this research is a container management system REST API that ensures isolation between users, server security, and container management efficiency. REST API testing uses black box testing with four scenarios. The test results show successful implementation on all endpoints based on each scenario between the results and input are as expected. This research can also be used as a reference for the development of container management systems on other types of HPC.
Keyword: Docker, Container, HPC, NVIDIA DGX A100

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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