Judul: Profil Metabolik Umbi Tiga Spesies Amorphophallus Indonesia
Abstrak: Umbi dorman dari tiga species Amorphophallus yakni iles-iles (Amorphophallus muelleri), suweg (A. paeoniifolius) dan acung (A. variabilis) dievaluasi menggunakan GC-MS dalam rangka mengetahui kandungan metabolomiknya. Umbi adalah umur 2 tahun, yang ditanam di Kebun Percobaan Leuwikopo, IPB, Darmaga, Indonesia. Pengujian metabolomik dilakukan di Laboratorium Litbang Kesehatan Jakarta. Pelarut yang digunakan untuk ekstraksi adalah pelarut polar berupa air. Hasil menunjukkan adanya keragaman kandungan senyawa pada ketiga umbi yang diuji. Terdapat 12 senyawa yang termasuk dalam kelompok antioksidan-vitamin, asam lemak jenuh, asam lemak tidak jenuh, fitosterol, alkohol, aldehid dan alkena yang dapat digunakan untuk membedakan species tersebut.
Keyword: Amorphophallus muelleri, Amorphophallus paeoniifolius, Amorphophallus variabilis, metobolomik, kekerabatan

Judul: Metabolomic of Three Antibacterial Potential
Medicinal Plant Species in Belitung Regency
Abstrak: Pemanfaatan Ipomoea cairica, Poikilospermum suaveolens, dan Schima wallichii sebagai tumbuhan obat telah dilakukan oleh masyarakat Melayu di Kabupaten Belitung secara turun- menurun. Namun, informasi mengenai senyawa kimia spesifik yang terkandung pada ketiga spesies tersebut masih terbatas. Penelitian ini bertujuan menganalisis senyawa metabolit tak tertarget pada I. cairica, P. suaveolens, dan S. wallichii yang berpotensi sebagai obat antibakteri dan digunakan sebagai pembeda antar spesies dengan pendekatan analisis metabolit berbasis LC-MS/MS. Sampel daun diekstraksi dengan teknik maserasi menggunakan pelarut etanol. Analisis metabolomik tak tertarget dilakukan menggunakan LC-MS/MS (UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS ThermiScientific). Data metabolit dianalisis dengan perangkat lunak Mzmine 3.9.0 dan Metaboanalyst 6.0. Hasil analisis menunjukkan sebanyak 755 metabolit terdeteksi pada ketiga spesies yang diamati. Kelompok metabolit yang teridentifkasi pada ketiga spesies adalah asam amino, asam lemak, terpenoid, flavonoid, alkaloid, steroid, kumarin, dan fenolik. Senyawa dominan yang terdeteksi pada masing-masing kelompok menunjukkan adanya potensi antibakteri. Senyawa kaskarosida C, arctigenin, eserolin fumarat, akanthosida merupakan kandidat penanda kimia spesies I. cairica. Senyawa 2-Quinolinekarboksilat, klovanediol diasetat, ramipril, dan metil deoksikolat merupakan kandidat senyawa spesies P. suaveolens. Senyawa apigenin-7-O-glukuronida, procyanidin B2, ginnalin A, dan kamellikaempferosida B merupakan kandidat penanda kimia spesies S. wallichii. Analisis gugus berdasarkan ciri metabolit mengelompokan seluruh individu menjadi 3 kelompok sesuai dengan spesiesnya. Spesies S. wallichii lebih dekat dengan spesies P. suaveolens berdasarkan profil metabolit ketiga spesies tersebut.
Keyword: heatmap, LC-MS/MS, metabolit, analisis gugus, biomarker

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
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