Judul: Analisis Willingness to Pay (WTP) dan Strategi Pengembangan Objek Wisata Pantai Lampuuk di Nanggroe Aceh Darussalam
Abstrak: Pantai Lmapuuk berada di kabupaten Aceh Besar Nanggroe Aceh Darussalam. Keindahan alam yang dimiliki telah menjadikan pantai Lmapuuk objek wisata yang banyak dikunjungi wisatawan. Pemerintah dalam melakukan pengembangan dan pengelolaan kekurangan dana.
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Judul: Kajian Sumberdaya Pantai Pasca Tsunami 2004 Untuk Pengembangan Wisata Pantai Lampuuk Kabupaten Aceh Besar Provinsi NAD
Abstrak: Pantai Lampuuk merupakan salah satu pantai yang terdapat di Kabupaten Aceh Besar. Pantai ini umumnya digunakan untuk kegiatan wisata seperti berenang, memancing, menikmati pemandangan, olahraga air dan snorkling. Tujuan dari penelitian ini adalah : (a) mengetahui keadaan fisik Pantai Lampuuk sebelum dan sesudah tsunami sebagai upaya bentuk atau sistem perlindungan wisata pantai terhadap ancaman tsunami, (b) menilai kesesuaian ekologis kawasan pantai dengan mengestimasi daya dukung kawasan Pantai Lampuuk untuk kegiatan wisata, (c) mengetahui persepsi wisatawan dan masyarakat sekitar terhadap kualitas lingkungan di kawasan Pantai Lampuuk, (d) mengetahui nilai ekonomi kegiatan wisata di kawasan Pantai Lampuuk. Penelitian ini dilakukan di kawasan Pantai Lampuuk Kabupaten Aceh Besar pada bulan Maret 2010 sampai bulan April 2010. Metode pengumpulan data yang diambil meliputi data primer (meninjau langsung) dan data sekunder (studi pustaka, buku-buku dan laporan ilimiah).
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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