Judul: Efikasi Pencegahan Hiperkolesterolemia Dengan Kombinasi Emping Ketan Hitam dan Dadih Secara In Vivo pada Tikus Percobaan
Abstrak: Hiperkolesterolemia merupakan salah satu faktor risiko terjadinya penyakit kardiovaskular. Penelitian ini bertujuan menganalisis efek emping ketan hitam dan dadih sebagai pencegahan hiperkolesterolemia secara in vivo pada hewan coba tikus. Penelitian ini menggunakan 15 ekor tikus putih yang dibagi menjadi tiga kelompok perlakuan, yaitu kelompok kontrol negatif (A), hiperkolesterolemia (B), dan pencegahan hiperkolesterolemia. Penelitian dilaksanakan selama 5 minggu, tikus kelompok kontrol negatif (A) diberi aquades, kelompok hiperkolesterolemia (B), diberi diet kolesterol 1%, dan kelompok pencegahan kolesterolemia (C) diberi emping dadih. Darah tikus diambil pada minggu ke 2, 4, dan 5 dan dianalisis kadar kolesterol total, LDL, HDL, dan trigliserida. Hasil penelitian ini menunjukkan pemberian emping dadih berpengaruh nyata terhadap pencegahan hiperkolesterolemia. Kelompok yang diberi emping dadih menunjukkan pencegahan kenaikan kadar LDL dan kolesterol hati, namun tidak berpengaruh terhadap HDL. Kandungan lemak yang tinggi pada emping dadih membuat kadar trigliserida yang meningkat.
Keyword: black, glutinous rice, cholesterol, dadih, HDL, LDL

Judul: Efficacy of Dadih and Black Glutinous Rice as an Cholesterol Lowering Alternative (Antihypercholesterolemia) in Hypercholesterolemic Rats Model
Abstrak: Hiperkolesterolemia merupakan faktor resiko penyakit kardiovaskular seperti aterosklerosis. Penelitian ini bertujuan menganalisis kadar total kolesterol, trigliserida, High Density Lipoprotein (HDL), dan Low Density Lipoprotein (LDL) dalam darah, serta kolesterol organ hati pada tikus hiperkolesterolemia yang diberi dadih dan ketan hitam (emping-dadih) dibandingkan dengan obat atorvastatin. Penelitian ini menggunakan 10 ekor tikus putih yang dibagi menjadi dua kelompok perlakuan, yaitu kelompok “emping-dadih” (ED) dan atorvastatin (AT). Penelitian dilaksanakan 9 minggu mencakup 5 minggu pertama diberikan diet kolesterol 1%, dan 4 minggu terakhir kelompok ED diberikan “emping-dadih” serta kelompok AT diberikan atorvastatin. Berdasarkan studi ini dapat disimpulkan bahwa “emping-dadih” dengan dosis tertentu mempunyai kemampuan yang sama dengan atorvastatin dalam menurunkan kadar kolesterol total dan LDL. Keduanya tidak memiliki efek berbeda terhadap kadar HDL. “Emping-dadih” berpotensi menaikkan kadar trigliserida walaupun dalam studi ini masih dalam rentang normal. “Emping-dadih” juga mampu menjaga kadar kolesterol hati tikus sama seperti kelompok yang diberi atorvastatin., Hypercholesterolemia is a risk factor for cardiovascular diseases such as atherosclerosis. This study aimed to analyze the levels of total cholesterol, triglycerides, High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL) in the blood, as well as liver cholesterol in hypercholesterolemic rats given dadih and black glutinous rice (emping-dadih) compared to atorvastatin. This study used 10 white rats divided into two treatment groups, i.e., the group treated with “emping-dadih” (ED) and the group treated with atorvastatin (AT). This study was conducted for 9 weeks. The first 5 weeks, all groups were given 1% cholesterol diet, and the last 4 weeks, the ED group was given emping dadih, and AT group was given atorvastatin. Based on this study, “emping dadih” can be concluded that “emping-dadih” with a certain dose has the same ability as atorvastatin in reducing total and LDL cholesterol levels. Both also have no different effect on HDL levels. “Emping dadih” has a potential to raise triglyceride levels even though in this study it is still within the normal range. “Emping-dadih” also maintained liver cholesterol levels the same as the atorvastatin rat group with no noticeable difference.
Keyword: black glutinous rice, dadih, hypercholesterolemia, LDL, Rat

Judul: Characteristic of Overshooting Top (OT) Based on  Himawari  8  Satellite  as  a  Convective  Cloud  Feature  that  Generates  Extreme Weather in the Java Island Region
Abstrak: Overshooting Top (OT) is a feature at the top of a convective cloud that is associated with extreme weather. Research on OT in tropical Indonesia is still very limited. The existence of geostationary satellites with wide area coverage and fast frequency observations is useful for observing the fast dynamics of the OT life cycle. Therefore, this study intends to analyze the relationship between OT and extreme weather, updraft and thermodynamic conditions of OT when extreme weather occurs, the best objective method for detecting OT in the day time and night time, and the spatiotemporal distribution of OT in the tropical region of Java Island during the 2018-2021 period. Based on visual analysis using visible channel and Himawari 8 sandwich products, 87% of extreme weather events in Java were accompanied by the appearance of OT. It indicates that the presence of the OT pattern is a convection cloud pattern or feature that is closely related to extreme weather events for the Java Island region. The existence of a time lag between the appearance of OT and extreme weather events on Java Island indicates that the OT of convection cloud can be used as a precursor or nowcasting for the appearance of extreme weather. Most of the convective cloud OT features during extreme weather events on Java Island have altitude that were only able to exceed the altitude of the equilibrium level and few were able to exceed the tropopause level of 9 km – 16 km. The difference in atmospheric conditions during extreme weather events on Java Island, which is in the tropics and subtropics, is a strong and unstable convective energy condition characterized by a larger CAPE, as well as unstable KI, LI, SI and TTI values. It is offset by kinematic factors in the form of a weak vertical wind shear (bulk wind shear 0-6 km) and a higher freezing point height. The difference between extreme weather events in the Java Island region and other tropical regions compared to subtropical regions is the strong updraft speed of convection clouds. The IRW Texture COMB algorithm based on the IRW-Texture Gradient modification and the COMB algorithm shows a significant increase in quality for detecting OT and non-OT pixels in Java. Rainy days with rainfall > 50 mm/day are very common in areas with an altitude of > 500 m. On the other hand, the level of convection activity which is indicated by the presence of OT and lightning is significantly reduced in this area. OT of convective clouds appear more frequently during the DJF season and less frequently during the JJA season. OT often appears during the day time and rarely at night time. Most OTs appear in the central part, away from the south and north coasts of Java Island during the day, while OTs that appear near the south and north coasts of Java Island can appear in the morning or afternoon.
Keyword: convective clouds, extreme weather, Overshooting Tops, Himawari 8 Satellite