Judul: Analysis of Beverage Inventory Control at PT XYZ Dramaga, Bogor Regency
Abstrak: Pertumbuhan pasar teh dan boba di Indonesia sedang mengalami pertumbuhan yang cepat. Salah satu merk teh dan boba yaitu PT XYZ yang memiliki cabang di Dramaga. Saat ini cabang tersebut mengalami kendala dalam mengelola persediaan karena permintaan yang fluktuatif tiap bulannya. Fokus pada penelitian ini adalah mengelola persediaan dari Choco Lava Milo dan Mango Yakult karena permintaannya yang cukup tinggi. Tahap awal dilakukan peramalan sebagai dasar untuk mengendalikan persediaan. Perhitungan persediaan dilakukan dengan Economic Order Quantity (EOQ). Metode peramalan yang dipilih adalah trend analysis karena tingkat kesalahannya terkecil. Berdasarkan hasil EOQ, kuantitas pemesanan optimum untuk Choco Lava Milo sebanyak 241 cup dan Mango Yakult sebanyak 244 cup. Total biaya persediaan yang dikeluarkan dengan EOQ adalah Rp3.367.898 sehingga gerai dapat menghemat biaya sebesar Rp 399.664 per tahun., The growth of the tea and boba market in Indonesia is experiencing rapid growth. One of the tea and boba brands is PT XYZ which has a branch in Dramaga. Currently, the branch is experiencing problems in managing inventory due to fluctuating demand every month. The focus of this research is managing the supply of Choco Lava Milo and Mango Yakult because demand is quite high. The initial stage is forecasting as a basis for controlling inventory. Inventory calculations are carried out using Economic Order Quantity (EOQ). The forecasting method chosen is trend analysis because the error rate is the smallest. Based on the EOQ results, the optimum order quantity for Choco Lava Milo is 241 cups and Mango Yakult is 244 cups. The total inventory costs incurred with EOQ are IDR 3.367.898 so the outlet can save costs of IDR 399.664 per year.
Keyword: Demand forecasting,, inventory control, EOQ, safety stock, Reorder Point

Judul: Demand Forecasting and Material Requirement Planning for a Tea and Boba Beverage Outlet
Abstrak: Pertumbuhan pasar minuman teh dan boba telah berkembang cepat di Indonesia. Gerai Haus! Dramaga merupakan salah satu gerai minuman teh dan boba yang mengalami kendala dalam perencanaan kebutuhan material/ bahan baku disebabkan perbedaan fluktuasi permintaan pada varian produk yang beragam, khususnya minuman. Penelitian ini dilakukan dari bulan Oktober 2023-Februari 2024 di gerai Haus! Dramaga, Bogor. Tujuan penelitian ini untuk mengetahui strategi proses produksi, mengklasifikasikan varian produk minuman menggunakan ABC Class-Based, menentukan metode peramalan terbaik produk varian minuman prioritas utama diantara metode Trend Analysis, Double Exponential Smoothing, dan Decomposition, dan menentukan kebutuhan jumlah dan jadwal pemesanan material/ komponen varian produk minuman pilihan. Strategi proses produksi yang diterapkan gerai Haus! Dramaga adalah strategi proses fokus berulang. Terdapat 12 varian produk minuman yang termasuk kategori produk prioritas utama. Metode peramalan terbaik untuk 10 varian adalah metode Trend Analysis. Sedangkan metode peramalan terbaik dua varian sisanya adalah metode Decomposition. Berdasarkan hasil peramalan, terdapat tiga varian yang mengalami trend kenaikan pada permintaan, yaitu Choco Cheese Crunchy, Choco Ovaltine dan Strawberry Tea. Jumlah kebutuhan komponen varian Choco Cheese Crunchy diperoleh dari kalkulasi Bill of Material dan Jadwal Induk Produksi, dengan jadwal pemesanan maksimal 12 kali per tahun dan ukuran lot pemesanan berdasarkan kebutuhan bulanan.
Keyword: ABC Class Based, Bill of Material, Material Requirement Planning, Peramalan Permintaan

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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