Judul: Evaluasi Aktivitas Antidiare Isolat Lactobacillus dari Air Susu Ibu
Abstrak: Sebagian besar isolat Lactobacillus yang berasal dari air susu ibu (ASI) diketahui memiliki sifat antimikroba termasuk terhadap E. coli. Berdasarkan hasil penelitian sebelumnya, isolat-isolat tersebut mampu bertahan dalam lingkungan asam dan garam empedu sehingga menjadi kandidat probiotik. Penelitian ini bertujuan mengetahui aktivitas antimikroba isolat Lactobacillus asal ASI terhadap isolat E. coli patogenik (EPEC K1.1) dan mengetahui efektivitas isolat Lactobacillus asal ASI untuk mencegah kejadian diare pada tikus percobaan serta untuk menentukan tiga isolat Lactobacillus asal ASI yang dapat mencegah diare pada tikus percobaan.
Keyword: 

Judul: Potensi bakteri asam laktat probiotik indigenus sebagai antidiare dan imunomodulator pada tikus percobaan
Abstrak: Diare akut merupakan penyebab utama kematian bayi di negara-negara berkembang, termasuk Indonesia. Beberapa bakteri patogen penyebab diare yaitu Escherichia coli, Shigella sp., Salmonella sp., dan Helicobacter pylori (Lestari, 2009). WHO menyatakan ada sekitar 4 milyar kasus diare infeksi setiap tahun dengan tingkat mortalitas 3-4 juta per tahun (Zein et. al., 2004). Arief (2008) telah berhasil mengisolasi 10 BAL indigenus dari daging sapi yang berasal dari beberapa pasar tradisional di daerah Bogor. Ke-10 BAL tersebut memiliki karakteristik sebagai bakteri probiotik dan menghasilkan senyawa antimikroba yang menghambat pertumbuhan bakteri enteropatogenik seperti Enterotoxigenic Escherichia coli (ETEC), Staphylococcus aureus, dan Salmonella typhimurium. Secara in vitro, ke-10 BAL tersebut diuji aktivitas antimikrobanya terhadap Enteropathogenic Escherichia coli (EPEC). Berdasarkan hasil identifikasi diketahui bahwa Lactobacillus plantarum 2C12 dan Lactobacillus fermentum 2B4 memiliki penghambatan terbaik terhadap EPEC (Arief, 2008). Berdasarkan beberapa fakta tersebut, dalam penelitian ini akan diteliti lebih lanjut mengenai potensi BAL, terutama L. plantarum 2C12 dan L. fermentum 2B4, sebagai antidiare dan imunomodulator. Penelitian ini dilakunan secara in vivo menggunakan tikus percobaan.
Keyword: 

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
Keyword: