Judul: Perubahan Sosial Masyarakat Desa Bantarjati, Kecamatan Klapanunggal, Kabupaten Bogor
Abstrak: Bantarjati merupakan desa yang berada di sekitar kawasan industri atau bangunan pabrik, kondisi tersebut memberikan perubahan pada kehidupan masyarakat. Penelitian ini dilakukan untuk menganalisis sumber yang menyebabkan perubahan sosial, fenomena perubahan sosial, hubungan antara karakteristik individu dengan sikapnya terhadap perubahan sosial yang terjadi, dan tingkat kesejahteraan masyarakat desa. Metode dalam penelitian ini adalah metode kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa terjadi perubahan sosial dalam beberapa aspek, yaitu terjadi perubahan lapisan sosial pada masyarakat, terbentuknya kelompok-kelompok sosial yang baru, perubahan pada aktivitas ekonomi masyarakat, perubahan pada nilai-nilai budaya masyarakat, dan kesejahteraan masyarakat desa. Sikap masyarakat terhadap perubahan yang terjadi sebagian besar bernilai netral, kemudian positif, dan pada urutan terakhir bernilai negatif. Pada karakteristik usia dan lama pendidikan memiliki hubungan yang negatif dengan sikap masyarakat sikap masyarakat terhadap perubahan yang terjadi. Kemudian pada karakteristik tingkat pendapatan memiliki hubungan yang rendah dengan sikap masyarakat. Selain itu, jenis kelamin dan jenis pekerjaan tidak memiliki perbedaan yang nyata dengan sikap masyarakat.
Keyword: Bogor Agricultural University, Institut Pertanian Bogor, Cultural values, Public attitudes, Social structures, Human ecology, Rank spearman, Chi-square, Rural community, Industrial area, Social culture, IPB

Judul: Perubahan Sosial Budaya Masyarakat Desa Lingkar Kampus sebagai Dampak Keberadaan Institut Pertanian Bogor
Abstrak: The objectives of this research is to analyze the waves of social change that occurred in Babakan Village since the presence campus of IPB. The result showed that the impact that caused is impact on community life aspects that is structural aspects and cultural aspects of Babakan village community. The changes on structural aspects are the increase of livelihoods diversity, the patterns of stratification changes, the establishment of new social groups, increasingly fading of social interaction and demographic pattern changes. Besides that, the changes on cultural aspects of community are the elements of rural culture changes, the shift of values and norms that exist in the society and also life style change of the rural community. Public attitudes towards the existence of campus of IPB mostly positive value. Public attitudes towards the presence of IPB’s campus has a negative relationship with society characteristics including age, income level and period of resided in Babakan village. Education level have positive relationship with public attitudes. There is also no significant differences in gender characteristic in the formation of attitudes towards the existence campus of IPB.
Keyword: public attitudes, structural and cultural change, Social change

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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