Judul: Keefektifan minyak mimba [Azadirachta indica] terhadap persembuhan seabies pada kelinci [Orytolagus cuniculus]
Abstrak: Penelitian ini bertujuan untuk mengetahui keefektifan minyak mimba sebagai obat herbal alternatif untuk pengobatan scabies. Sebanyak 8 ekor kelinci yang telah terinfeksi scabies secara alamiah (naturally infected) dibagi menjadi 2 kelompok, masing-masing kelompok berjumlah 4 ekor. Kelompok pertama diobati dengan sediaan gammexane (S1,2,3,4) secara topikal sehari dua kali (pagi dan sore) selama satu bulan, kelompok dua diobati dengan minyak mimba (M1,2,3,4) secara topikal sehari dua kali (pagi dan sore) selama satu bulan. Sebagai kontrol digunakan satu ekor kelinci yang juga telah terinfeksi scabies. Hasil penelitian menunjukkan bahwa keefektifan minyak mimba sama dengan sediaan gammexane, khususnya untuk menyembuhkan luka atau kerak akibat scabies, dan juga efektif untuk mengurangi luasan lesio scabies. Walaupun demikian, minyak mimba tidak efektif untuk meningkatkan pertumbuhan rambut pada kebotakan akibat scabies. Waktu yang dibutuhkan minyak mimba untuk persembuhan scabies lebih lambat dibandingkan gammexane. Aktifitas kerja obat gammexane dan minyak mimba rata-rata bekerja setelah minggu ke-2 pengobatan….
Keyword: Scabies, Neem oil, Gammexane, Azadirachta indica, Orytolagus cuniculus

Judul: Potential of Areca Nut Seeds (Areca catechu) and Noni (Morinda citrifolia) as Antiscabies in Rabbits Infected with Sarcoptes scabiei.
Abstrak: Skabies adalah penyakit kulit yang disebabkan oleh tungau Sarcoptes scabiei dan hidup di jaringan kulit. Kelinci merupakan salah satu hewan yang sering terinfeksi skabies. Penelitian ini bertujuan untuk melihat potensi yang dimiliki oleh biji pinang dan mengkudu sebagai antiskabies pada kelinci yang terinfeksi skabies. Penelitian ini menggunakan dua puluh empat ekor kelinci yang terbagi menjadi empat kelompok yakni kontrol negatif, kontrol positif, krim biji pinang 5%, dan krim mengkudu 5%. Setiap kelompok terdiri dari enam ekor kelinci. Hewan percobaan diberikan olesan krim setiap hari sebanyak dua kali pagi dan sore hari. Persembuhan luka diamati pada hari ke-0, 5, 10, 15 lalu diberi nilai skoring. Hari ke-0 dan hari ke-15 dilakukan skin scraping lalu dilakukan pemeriksaan mikroskopis untuk konfirmasi jumlah tungau Sarcoptes scabiei pada kelinci yang terinfeksi skabies. Hasil dari penelitian ini memperlihatkan keropeng pada kelinci yang terinfeksi skabies setelah diberi krim biji pinang dan krim mengkudu menunjukkan persempitan atau penutupan luka dan pengurangan jumlah tungau Sarcoptes scabiei pada pemeriksaan mikroskopis. Berdasarkan analisis dengan metode molecular docking, senyawa aktif dari biji pinang dan mengkudu memiliki potensi untuk pengobatan skabies. Senyawa aktif didalam ekstrak biji pinang dan mengkudu yang diduga menunjukan antiskabies adalah arecoline (-5.68 kkal/mol) dan anthraquinone (7.39 kkal/mol). Hasil ini menggambarkan biji pinang dan mengkudu memiliki potensi dan dapat digunakan sebagai pengobatan alternatif untuk kasus skabies., Scabies is a skin disease caused by the Sarcoptes scabiei mite and lives in skin tissue. Rabbits are one of the animals that are often infected with scabies. This research aims to see the potential of areca nut and noni seeds as anti-scabies in rabbits infected with scabies. This study used twenty-four rabbits which were divided into four groups, namely negative control, positive control, 5% areca nut cream, and 5% noni cream. Each group consists of six rabbits. Experimental animals were given cream every day twice in the morning and evening. Wound healing was observed on days 0, 5, 10, 15 and then scored. On days 0 and 15, skin scraping was carried out and then a microscopic examination was carried out to confirm the number of Sarcoptes scabiei mites in rabbits infected with scabies. The results of this study showed that scabs on rabbits infected with scabies after being given betel nut cream and noni cream showed narrowing or closure of the wound and a reduction in the number of Sarcoptes scabiei mites on microscopic examination. Based on analysis using the molecular docking method, active compounds from areca nut and noni seeds have the potential to treat scabies. The active compounds in areca nut and noni seed extracts which are thought to exhibit antiscabies are arecoline (-5.68 kcal/mol) and anthraquinone (7.39 kcal/mol). These results illustrate that areca nut and noni seeds have potential and can be used as an alternative treatment for scabies cases.
Keyword: kelinci, Sarcoptes scabiei, biji pinang, mengkudu, molecular docking

Judul: Distribusi Tegangan-Regangan pada Tahap Konstruksi Struktur Atas Jalan Layang Tol BORR (Bogor Outer Ring Road) Seksi IIA Span P6 – P12
Abstrak: Land transportation network system consists of road and bridge, both of them has important role in connecting each region, in addition to support the transportation activity inside. Bogor city government had planned construction of Elevated Toll Road, Bogor Outer Ring Road (BORR) Section IIA on Kedunghalang – Kedungbadak roads to reduce the congestion occurs in that region currenly. The constructin concept is segmental bridge and precast segmental box girder as main component, construction method which used is “span by span erection with launching gantry”. The purpose of this research is to analyze the stress-strain and displacement that occurs on top of structre when the construction stage takes place. The methods of this research are collecting data, modelling in CSI Bridge V15, and analysis of stress-strain distribution. During the construction process, the entire structure of the box girder and column are secure against stress and compressive strain, but with the addititonal condition which is most of box girder structure and all of column structure is unsafe to stress and tensile strain. Compressive stress, tensile stress, compressive strain and tensile strain that occurs in span 2 of box girder (76 614 mm distance) after the construction steps are finished is represents respectively 2122.39 kN/m2, 3412.96 kN/m2, 7.01E-05, and 1.13E-04. In addition, the compressive stress, tensile stress, compressive strain and tensile strain that occurs in column 2 side A after constructions work is finished, the results gained are presented continously as 3632.5 kN/m2, 5708 kN/m2, 1.2E-04, and 1.89E-04, while on the B side are 4570.5 kN/m2, 7176.2 kN/m2, 1.51E-04 and 2.37E-04. The maximum deflection occurs at step 11 and 12 is in the amount of 16.7 mm, these results indicate that the structure of bridges / fly-over is stiff and safe.Obtained maximum deflection is 16.7 mm, the results show that the structure of the bridge/ fly-over is safe.
Keyword: CSI Bridge V15, span by span with launching gantry, box girder, stress-strain