Judul: Profil Metabolit Ekstrak Daun Sembung (Blumea balsamifera) Menggunakan Kromatografi Cair-Spektrometri Massa
Abstrak: Sembung (Blumea balsamifera) merupakan tanaman herbal yang banyak digunakan untuk mengobati berbagai penyakit. Khasiat tanaman tersebut ditentukan oleh metabolitnya. Komposisi metabolit tanaman berbeda-beda dan dipengaruhi oleh beberapa faktor, di antaranya lokasi tumbuh dan jenis pelarut pengekstraksi. Penelitian ini bertujuan mengidentifikasi metabolit ekstrak daun menggunakan kromatografi cair-spektrometri massa/spektrometri massa (LC-MS/MS). Sampel asal Bogor dan Sukabumi dimaserasi menggunakan pelarut air dan etanol 70%. Kromatogram LC-MS/MS diolah menggunakan perangkat lunak Thermo Scientific Xcalibur 4.2 dan MZmine 2.53. Sebanyak 47 senyawa berhasil diidentifikasi. Dalam sampel asal Bogor, teridentifikasi 28 senyawa dalam ekstrak air dan 31 senyawa dalam ekstrak etanol 70%. Adapun senyawa asal Sukabumi yang terekstraksi dengan kedua pelarut tersebut masing-masing berjumlah 33. Senyawa tersebut termasuk golongan monoterpena, flavonoid, asam fenolat, kumarin, asam karboksilat, lignan, furan, asam ftalat, seskuiterpena lakton, dan kalkon.
Keyword: Blumea balsamifera, kromatogram, metabolit sekunder, MZmine

Judul: Pemprofilan Metabolit Ekstrak Daun dan Batang Sambiloto (Andrographis paniculata) Menggunakan Kromatografi Cair-Spektrometri Massa.
Abstrak: Sambiloto (Andrographis paniculata) banyak digunakan sebagai tanaman obat yang khasiatnya ditentukan oleh komposisi metabolit didalamnya. Komposisi metabolit yang terkandung dalam tanaman ini dapat dipengaruhi oleh beberapa faktor, salah satunya bagian tanaman yang diekstrak. Penelitian ini bertujuan mengidentifikasi komoposisi metabolit ekstrak daun dan batang sambiloto menggunakan kromatografi cair-spektrometri massa (LC-MS/MS) dan mengelompokkan dengan principal component analysis (PCA). Sampel batang dan daun dipisahkan dan diekstraksi dengan sonikasi menggunakan etanol 70%. Sebanyak 31 senyawa metabolit berhasil teridentifikasi dalam ekstrak. Senyawa metabolit tersebut termasuk dalam golongan asam fenolat, diterpen lakton, dan flavonoid. Berdasarkan hasil klasifikasi, setiap ekstrak terkelompok dalam kelasnya masing-masing, yaitu batang dan daun dengan total plot skor 92%.
Keyword: Andrographis paniculata, LC-MS/MS, metabolit sekunder, PCA

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
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