Judul: Proses Peroksida Lipid Kelinci Hiperlipidemia pada Pemberian Senyawa Penurun Kolesterol
Abstrak: Radikal bebas banyak mendapat perhatian akhir-akhir i11i karena dianggap memiliki peran yang cukup signifikan dalam tejadinya berbagai penyakit degeneratif. Hiperlipidemia adalah salah satu faktor resiko utama dari aterosklerosis yang mengarah pada penyakit degeneratif tersebut. Penelitian ini bertujuan mengukur konsentrasi lipid peroksida pada darah kelinci yang hiperlipidemia dan pengaruh senyawa penurun kolesterol terhadap konsentrasi lipid peroksidanya. Sebanyak 20 ekor kelinci jantan galur New Zealand white dibagi menjadi empat kelompok percobaan, yaitu kelompok normal yang hanya diberi pakan standar, hiperlipidemia yang diberi pakan aterogenik (kolesterol 0.5% dan minyak kelapa 5%), lovastatin yang diberi campuran pakan aterogenik dan lovastatin (57 mglhari), dan ekstrak yang diberi campuran pakan aterogenik dan ekstrak ramuan daun jati belanda.
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Judul: Proses Peroksidasi Lipid Kelinci yang Hiperlipidemia pada Pemberian Senyawa Penurun Kolesterol
Abstrak: Free radicals, such as lipid peroxide, are having much attention right now because their significant role in degenerative disease. Hyperlipidemia is one of the major risk factor for atherosclerosis and lead to degenerative disease. The aim of this study was to determine the effect of cholesterol lowering substance to the blood peroxide lipid concentration in hyperlipidemic rabbit. Twenty four male New Zealand white rabbits were divided into four groups: normal (given standard rabbit feed), hyperlipidemia (given atherogenic rabbit feed contained 0.5% cholesterol and 5% coconut oil), lovastatin (given mixture of atherogenic rabbit feed and lovastatin 57 mg/day), and extract (given atherogenic rabbit feed and jati belanda leaves extract mixture). Thiobarbitnric acid (TBA) method was used in blood lipid peroxide analysis, measuring the MDA product by spectrophotometer at 532 nm. The result showed that the atherogenic rabbit feed caused the elevation of MDA concentration, which means the elevation of lipid peroxidation process. Blood lipid peroxide concentration in hyperlipidemia group increased 163.76% compared with normal group (1.30 ± 0.38 nmol/ml). Lovastatin and jati belanda leaves extract mixture can act as antioxidant which can lowering blood lipid peroxide concentration 46.92% and 53.03% respectively at 8th week compared with hyperlipidemia group.
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Judul: The impact and contribution of the tourism sector to the Indonesian economy : an I-O and SAM approach
Abstrak: Tourism is an important and strategic sector for the Indonesian economy. The sector has been growing for the last two decades to enhance its contribution to the GDP, employment, regional, local economy, and to strengthen the balance of payment. In particular, a planned economy was introduced to provide substantial opportunities to utilize tourism as a mechanism for national development. As a service-based sector, tourism as also considered to be a vehicle of converting the manufacturing economy to a service economy which makes the delivery of the product rather than the creation of the product the most important thing.
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