Judul: Aktivitas antijerawat formula campuran meniran dan temu lawak serta aktivitas inhibisinya terhadap katalase Staphylococcus aureus
Abstrak: Acne is an inflammation of skin caused by Staphylococcus aureus, S. epidermidis, and Propionibacterium acnes bacteria. Antiacne activity of temu lawak and meniran has been analyzed through antibacterial activities against S. aureus and S. epidermidis and inhibition of S. aureus catalase activity. Temu lawak and meniran were extracted by using maceration technique in 96% ethanol with two different maceration methods, Indonesian and traditional chinese medicine. S. aureus and S. epidermidis were successfully isolated. The growth of S. aureus was inhibited by temu lawak extract with minimum bactericidal concentration (MBC) 150 ppm and inhibition zone index 0.38. The growth of S. epidermidis was inhibited by mixture of temu lawak 2/3 and meniran 1/6 with MBC 300 ppm and inhibition zone index 0.40. Thin layer chromatography profile of both extracts showed curcuminoid band. Catalase enzyme was successfully isolated from S. aureus. Mixture of temulawak 2/3 and meniran 1/6 gave the best catalase inhibition activity, 6.88% in 500 ppm formula concentration.
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Judul: Aktivitas antijerawat formula campuran temu lawak dan meniran serta penentuan sidik jari kromatografinya
Abstrak: Anti-acne activity of extracts from C. xanthorriza and P. niruri has been analyzed through antioxidant and antibacterial activity assays. Extraction process was conducted by two different maceration methods, Indonesian and traditional chinese medicine (TCM) with ethanol 96% as the solvent. Formula 6 (2/3 C. xanthorriza:1/6 P. niruri:1/6 starch) was the most active anti-acne formula with IC50 of antioxidant values of 93.17 ppm, the minimum inhibitory concentration against Staphylococcus epidermidis was 0.25 mg/mL, and the minimum bactericidal concentration was 0.50 mg/mL. Moreover, TCM maceration was better than the Indonesian method in terms of antioxidant and antibacterial activities. Fingerprint analysis of formula was undertaken using thin layer chromatography. The optimum mobile phase was chloroform that gave 9 bands. Further, the (HPLC) analysis with C18 as column and gradient of acetonitrile and water as the mobile phase showed that the peak area of phyllanthin and curcumin increased when the standard compounds were added into the sample.
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Judul: Analisis Struktur Atas Gedung Diploma IPB terhadap Beban Gempa Berdasarkan SNI 03-1726-2002 dan SNI 03-1726-2012
Abstrak: Gedung Diploma IPB masih menggunakan SNI 03-1726-2002 dalam perencanaan strukturnya. SNI tersebut kemudian diubah seiring dengan keluarnya peraturan baru yang termuat dalam SNI 03-1726-2012. Tujuan dari penelitian ini adalah mengetahui ketahanan struktur atas gedung Diploma IPB terhadap beban gempa ditinjau berdasarkan waktu getar alami dan partisipasi massa, mengetahui besarnya gaya geser dasar seismik, dan membandingkan besarnya simpangan berdasarkan kedua SNI. Partisipasi massa arah X yang dihasilkan yaitu sebesar 0.9417 pada modal ke 9 dan 0.9006 pada modal ke 12 pada arah Y. Kedua nilai tersebut telah memenuhi kedua standar SNI. Waktu getar alami telah memenuhi standar SNI 2002, namun belum memenuhi standar SNI 2012. Gaya geser dasar dinamik yang dihasilkan berdasarkan SNI 2012 sebesar 1599.6606 kN akibat gempa arah X dan 1223.5794 kN akibat gempa arah Y, sedangkan berdasarkan SNI 2002 untuk arah X sebesar 1544.5109 kN dan untuk arah Y sebesar 1544.8304 kN. Simpangan antar lantai telah memenuhi persyaratan kedua standar SNI. Struktur Gedung Diploma IPB telah memiliki kekakuan yang cukup dan terhitung boros, sehingga seharusnya dapat direncanakan dengan lebih hemat biaya.
Keyword: beban gempa, gaya geser dasar, simpangan, struktur atas