Judul: Pengaruh industrialisasi terhadap masyarakat pedesaan: Studi kasus Desa Bitung Sari, Kecamatan Ciawi, Kabupaten Bogor, Propinsi Jawa Barat
Abstrak: This research essentially aims to see and understand the impact of industrialization on rural communities. This research was conducted in Bitung Sari Village, Ciawi, Bogor. The subject of this research is the village government, community leaders, community members and the industries. This study investigated impacts of industrialization on rural community as well as on land use and environmental issues. The conclusion of this research is the Jae: that industrialization has led to social change in the aspect of demography. employment opportunities, business opportunities, types of livelihood, education, social cohesion and social stratification. In addition. industrialization has led to changes in land use and environmental pollution.
Keyword: Industrialization, Rural communities, Social change, Environmental issues

Judul: Industri dan Perubahan Sosial Ekonomi Masyarakat Pedesaan^bKasus desa Citeureup, Kecamatan Citeureup, Kabupaten Bogor, Provinsi Jawa Barat
Abstrak: Industrialisasi merupakan salah satu langkah pembangunan untuk mendorong pertumbuhan ekonomi.Dampakkehadiran industri yaitu mampu membuka peluang bekerja dan peluang berusaha bagi masyarakat, sehingga hal tersebut diharapkan dapat meningkatkan pendapatan warga di wilayah tersebut. Namun,kehadiran industri juga dapat menimbulkan perubahan pada berbagai bidang, misalnya sosial dan ekonomi masyarakat. Perubahan sosial ekonomi yang diamati pada penelitian ini yaitu pendapatan, pendidikan, ragam mata pencaharian, dan pola interaksi sosial. Penelitian ini bertujuan untuk menganalisis hubungan antara keberadaan industri yang dilihat dari besarnya peluang bekerja dan peluang berusaha dengan perubahan-perubahan yang terjadi di masyarakat khususnya perubahan sosial ekonomi yang mencakup lima aspek di atas. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kuantitatif yang didukung oleh data kualitatif. Hasil penelitian ini menunjukkan terdapat perbedaan hubungan antara keberadaan industri dengan perubahan sosial ekonomi masyarakat dalam sepuluh tahun terakhir.
Keyword: industrialisasi, peluang bekerja, peluang berusaha, perubahan sosial-ekonomi

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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