Judul: Potensi Metabolik Buah Merah Terhadap Perbaikan Hematologi dan Organ Tikus yang Diinduksi Kuinin
Abstrak: The aim of this research is to find out the influence of the red fruit extract (RFE) in the blood picture, liver and kidney of mice which induced quinine. Twenty five mice were divided into 5 groups; the groups are No (normal), the group K (quinine), the S1 (quinine and SBM 0,9 ml / kg BB/day), S2 groups (quinine and SBM 1,8 ml/ kg BB/day) and the S3 (only RFE dosage of 0,9 ml/kg BB/day). The blood sampling were done in the 0, 3rd, 7th, 10th, 14th, 17th, 20th, 23rd and 29th day. Nekropsi was done after the RFE was stopped. Liver and kidney organs were retrieved and processed into histopathology preparate with Haematoxylin-Eosin (HE) coloring. Histopathology examination was done for each group, by 20 observation of field perspective and the result were counted to get the average. Profile of blood does not change. Giving red fruit extract can increase the number of thrombocyte although statistically it was not significant (P>0,05). The damage of liver which caused by quinine, for instance hidropis degeneration, edema, and nekrosa were retarded by RFE treatment with dosage 0,9 ml/ kg BB/ day. The damage in kidney which caused by quinine (hidropis degeneration on tubuli cells, edema glomerulus, and the expansion lumen tubuli) was also retarded by the treatment. Degeneration of hidropis and nekrosa can expand in kidney with 1,8 ml/kg BB/day RFE.
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Judul: Hematological and Histopathological Organs Studies on Quinine Induced Rat as Metabolic Potential Test of Angkak.
Abstrak: This research was purposed to analyze potency of angkak on hematological parameters and organs recovery in quinine induced rat. Rats were randomly divided into five groups. Group I were given orally aquades, group II received 100 g/kg bb quinine 14 day afterward not received angkak, group III received 100 g/kg bb quinine 14 day afterward received 0.04 g/kg bb angkak 14 day, group IV received 100 g/kg bb quinine afterward received 0.08 g/kg bb angkak, and group V not received quinine afterward received 0.04 g/kg bb angkak. Hematology analysis measured every 3 day. At 29 th day, the rats were necropsied to see the lesion on the liver and kidney both macroscopically and microscopically. The treatment with angkak can increasing the body weight of the rats (p<0.05). Analysis result of platelet showed that treatment using 0.04 g/kg bb angkak able to increase the sum of platelets (p<0.05). The treatment using angkak have not demonstrated significantly effect on red blood cell, hemoglobin, and hematocrit (p>005). Observation histopathology of the test animals liver and kidney showed the treatment using 0.04 g/kg bb and 0.08 g/kg bb angkak was confirmed helping the liver and kidney to recover from histopathology lesion caused negative effect. Statistical analysis result showed that recover using angkak is differently significant.
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Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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