Judul: Sistem pelaporan otomatis data pokok Kecamatan Bimas
Abstrak: Tujuan penulisan ini ialah untuk melaporkan hasil dari usaha penyempurnaan dan pengembangan sistem informasi manajemen Data Pokok Kecamatan agar diperoleh penyajian informasi yang lebih cepat, tepat, dan dapat dipercaya. Sistem pelaporan ini dilaksanakan oleh Badan Pengendali Bimas Departemen Pertanian bekerja sama dengan Jurusan Statistika Fakultas Matematika dan IPA Institut Pertanian Bogor. Data yang digunakan berupa buku Daftar Isian Pertanyaan Data Pokok Kecamatan (DIPDPK) yang disimpan dalam disk yang terbagi dalam 5 arsıp data. mempercepat pengolahan data. Hal ini akan mempermudah dan Bentuk penyajian informasi yang dirancang tidak baku (bersifat bebas) tetapi terarah menurut pokok masalah yang dipilih. Hal ini akan memperbanyak bentuk laporan yang diinginkan oleh pengambil keputusan atau penarik kesimpulan.
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Judul: Perancangan Paket Program MAnajemen Data SP90-PODES di Biro Pusat Statistik
Abstrak: Sistem PODES90 dibuat untuk merekam data SP90-PODES di setiap propinsi dengan menggunakan mikrokomputer APC IV. Sistem ini dibuat dalam bahasa Cobol versi 3.00 dan merupakan sistem interaktif. Hasil rekaman data SP90-PODES oleh sistem PODES90 untuk setiap kabupaten disimpan dalam disket. Data ini di- olah di Biro Pusat Statistik dengan menggunakan mainframe NEC 1520 untuk menghasilkan informasi yang bersifat nasional.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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