Judul: Tinjauan Teori Permainan
Abstrak: Keterbatasan sumber daya alam dan penggunaan sumber daya alam seeara bersama-sama menyebabkan seluruh anggota masyarakat di mana pun menghadapi masalah pengambilan keputusan tentang apa yang hams diproduksi dan bagaimana membagi produk tersebut di kalangan anggota masyarakat. Mereka dihadapkan pada berbagai pilihan strategi dalam memaksimumkan imbalannya, dan setiap strategi yang dipilihnya akan menimbulkan dampak tertentu terhadap Iingkungan sekitamya. Tulisan ini membahas salah satu contob fenomena alam yang terjadi di suatu daerah peternakan yang menunjukkan bahwa jib perilaku setiap anggota masyarakat ditujukan banya untuk kepentingan pribadi saja malea benda-benda puhlik akan lebih cepat habis dan sumber daya publik akan lebih cepat rusak bahkan mungkin habis.-
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Judul: Analisis Persaingan Barga Vs Kuantitas Dengan Tingkat Kualitas Sebagai Variabel Endogen
Abstrak: Teori pennainan digunakan untuk mengembangkan pemaluunan mengenai _ di antara pembuat keputusan. Secara umum permainan terdiri atas himpunan pemain, himpunan strategi yang dapat diambil oleh setiap pemain, dan imbalan yang diperoleh setiap pemain dati setiap strategi. yang dipilih.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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