Judul: Gambaran Histopatologi Hati dan Ginjal Tikus Laktasi yang Diberi Ekstrak dan Fraksi Sauropus androgynus (L.) Merr Sejak Bunting Sampai 10 Hari Postpartus
Abstrak: This study was aimed to obtain the information about the possibility of side effects (toxic) from consuming of katuk (Sauropus androgynus) leaf extract and fractions using rats as experimental animals. Fifteen pregnant female rats were divided into 5 treatment groups; control (K), ethanol crude exstract (EEtOH), hexan fraction (F-H), ethylacetate fraction (F-EtAc), and water fraction (- FH2O). The katuk leaf extract and fraction were fed from the beginning of pregnancy until 10 days postpartus. Histopathological assay was conducted to investigate the effect of treatment to the liver and kidneys at 10 days postpartus. Histopathology of liver showed that the katuk leaves extract group F-H2O, F-EtAc, and E-EtOH are able to protect the hepatocyts of the liver from apoptosis, but the katuk leaves extract or their metabolites tended to increase the number of apoptosis on renal tubular epithelium of the kidneys. For both organs, the result indicated that the group of katuk leaves water fraction (F-H2O) treatment cause the minimal damage among the others.
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Judul: SARI. The Influence of Sauropus androgynus Leaf Extract and Fraction Administration on Rat’s Uterine Involution.
Abstrak: Penelitian ini dilakukan untuk menguji khasiat ekstrak dan fraksi daun katuk (Sauropus androgynus) terhadap involusi uterus dengan menggunakan tikus sebagai hewan percobaan. Sebanyak 15 ekor tikus betina bunting di bagi menjadi 5 kelompok perlakuan: kontrol (K), ekstrak etanol (E-EtOH), fraksi heksan (F-H), fraksi air (F-H2O), dan fraksi etil asetat (F-EtAc). Pengaruh perlakuan terhadap involusi uterus dilihat dengan mengukur berat uterus pada 5 hari postpartus dan 10 hari postpartus. Data yang diperoleh dari pengukuran dianalisis dengan menggunakan Uji Sidik Ragam (ANOVA) dan dilanjutkan dengan uji lanjut (Duncan Test). Hasil penelitian menunjukkan bahwa kelompok fraksi heksan dan ekstrak etanol pada 5 hari postpartus mengalami perlambatan involusi uterus, namun bobot uterus kedua kelompok ini sudah mencapai ukuran normal pada 10 hari postpartus. Involusi uterus pada kelompok fraksi etil asetat dan fraksi air terjadi lebih cepat dibanding kelompok lain. Bobot uterus kedua kelompok ini sudah mencapai bobot normal pada 5 hari postpartus, namun berat uterus semakin mengecil pada 10 hari postpartus. Kesimpulan dari penelitian ini adalah pemberian ekstrak dan fraksi daun katuk dapat mempengaruhi involusi uterus tikus
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Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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