Judul: Komposisi Jenis dan Struktur Tegakan Hutan Terganggu di Gunung Papandayan, Garut, Jawa Barat
Abstrak: Growth process of forest community to reach balanced condition often undergoes disturbances which create destruction. Papandayan mountain has been known since Dutch colonial government as an area with very rich floristic composition. Research on species composition and stand structure of disturbed forest has never been conducted in this area. The objective of this study is to learn the species composition and stand structure of disturbed forest in Papandayan mountain, whose forests are disturbed both by human and by natural process. Research results show that biodiversity and species richness in sites disturbed by human are higher than those disturbed by nature. Besides that, forest crown stratification pattern in disturbed forest shows that there is no any forest crown which reaches stratum A (>30 meter). They only reach stratum B (20–30 meter) and stratum C (4–20 meter). Crown stratification in disturbed forest never reached stratum A because stratum A constitutes the character of stable forest condition.
Keyword: stand structure, species composition, Papandayan Mountain, disturbed forest

Judul: Keanekaragaman Jenis Tumbuhan Bawah di Gunung Papandayan Bagian Timur, Garut, Jawa Barat.
Abstrak: Gunung Papandayan has the potential of various types of fauna and flora that has become the unity in its natural environment. The objectives of this research was to determine the composition, diversity and potential of undergrowth that are found in the eastern part of Gunung Papandayan. The total of undergrowth species on Gunung Papandayan approximately 101 species of 34 families. The level of undergrowth diversity on five sites varies with a value of highest H’ at Supabeureum (3.36), while Tegal Mariuk has the smallest value of H’ (2.40). The low level of vegetation dominance indicated that undergrowth in five sites spread on a lot of species. Undergrowth vegetation communities in five sites are differs with IS score was < 75 %. Undergrowth species which are found on Gunung Papandayan has potential as food, medicinal plants, ornamental plants, and livestock feed.
Keyword: undergrowth, Gunung Papandayan, diversity, analysis of vegetation

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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