Judul: Profil Hematologi dan Kimia Darah Beruk (Macaca nemestrina) yang Positif Terdeteksi Klebsiella pneumoniae
Abstrak: Klebsiella pneumoniae adalah bakteri gram negatif komensal, namun bisa bersifat patogen oportunistik pada mamalia contohnya satwa primata beruk (Macaca nemestrina). Satwa primata merupakan salah satu hewan model yang banyak dipelajari ilmu biomedis. Infeksi subklinis atau klinis pada hewan dapat mengubah keadaan fisiologis dari parameter komponen darah sehingga menjadi acuan status kesehatan. Pengujian hematologi dan kimia darah adalah salah satu penunjang diagnosa yang sering dilakukan. Tujuan penelitian ini adalah mengevaluasi profil hematologi dan kimia darah beruk yang positif Klebsiella pneumoniae. Penelitian ini memeriksa hematologi dan kimia darah dari enam sampel darah beruk betina dewasa yang terdeteksi Klebsiella pneumoniae oleh PCR dari swab nasofaring dan swab rektal, namun tidak menunjukkan gejala klinis. Hasil hematologi menunjukkan semua beruk mengalami penurunan eritrosit, hematokrit, dan Platelete Distribution Widht, serta kenaikan Mean Corpuscular Hemoglobin. Parameter kimia darah yang berubah pada semua beruk adalah kenaikan Blood Urea Nitrogen. Perubahan ini mengindikasikan gangguan anemia, penurunan trombopoiesis, dan azotemia dapat diakibatkan oleh infeksi Klebsiella pneumoniae. Beberapa beruk juga mengalami leukopenia dan hipoproteinemia diduga dapat terjadi akibat Klebsiella pneumoniae. Penelitian lanjutan diperlukan untuk memastikan hubungan temuan patologi klinik dengan proses patofisiologis infeksi Klebsiella pneumoniae.
Keyword: Blood profile, Klebsiella pneumoniae, Pathophysiology,, Pigtailed macaque

Judul: Analisis Hematologi dan Kimia Darah Macaca Fascicularis dengan Infeksi Positif terhadap Klebsiella Pneumoniae
Abstrak: Klebsiella pneumoniae belongs to the family Enterobacteriaceae and is found in mouth and intestine. Klebsiella pneumoniae has been reported in various nonhuman primate species with the cases of pneumonia, septicemia, and enteritis. This secondary study purposed to obtain information of clinical pathology profile related to Klebsiella infection in cynomolgus monkeys (Macaca fascicularis). This secondary study was conducted on three long-tailed monkeys which showed positive results in the bacterial culture test. The secondary study was based on blood analysis to evaluate hematology and blood chemistry. The results demonstrate that monkeys with Klebsiella pneumoniae exhibited marked changes in erythrocytes, hemoglobin, hematocrit and mean corpuscular hemoglobin concentration values in hematology as well as creatinine, total protein, and albumin levels and albumin/globulin ratio in blood chemistry profile. The changes may indicate the incidence of anemia, liver disease, thrombocytopenia, dehydration, inflammatory response and kidney disease, which may be associated with Klebsiella pneumoniae infection.
Keyword: Blood chemistry analysis, Hematological analysis, Klebsiella pneumoniae, Macaca Fascicularis

Judul: Formulasi TSP (Traveling Salesman Problem) menggunakan ILP (Integer Linear Programming)
Abstrak: TSP is a journey of salesman f?om his origin town (place) to visit n-cities (places) only at once, then return to his origin town (place) with a minimum total distance. Its purpose is to minimize the operating expense that is released by the company. Vehicle route at TSP in the form of a Hamiltonian cycle, that is closed path containing all nodes at the graph which representing a network walk. Its problem is to determine a journey route which is feasible (possibly can be passed by) in such a way the vehicle travelled distance passed the route is minimum.
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