Judul: Efek Pemberian Ekstrak Etanol Biji Mahoni Terhadap Profil Imunohistokimia Antioksidan Superoksida Dismutase (Sod) Pada Pankreas Tikus Model Diabetes
Abstrak: Penelitian ini bertujuan untuk menganalisis efek ekstrak etanol biji mahoni terhadap berat badan, kadar glukosa darah dan profil antioksidan copper, zinc-superoxide dismutase (Cu,Zn-SOD) jaringan pankreas tikus DM. Sejumlah 25 ekor tikus jantan putih galur Sprague Dawley telah digunakan pada penelitian ini, yang dibagi menjadi lima kelompok perlakuan, yaitu : (1) Kontrol negatif (KN), (2) Kontrol positif, tikus DM (KP), (3) Tikus DM yang diberi ekstrak etanol biji magoni (EM), (4) Tikus DM yang diberi obat acarbose 2 mg/Kg berat badan. dan (5) Tikus non DM yang diberi ekstrak etanol biji magoni (KE). Kondisi DM didapatkan dengan induksi alloxan 110 mg/kg bb pada tikus percobaan. Perlakuan ekstrak etanol biji mahoni dilakukan selama 28 hari. Berat badan, total konsumsi pakan, dan kadar glukosa darah dihitung selama masa perlakuan. Pada akhir perlakuan, tikus dianestesi dengan ketamine-xylazine dan organ pankreas diambil. Organ pankreas selanjutnya difiksasi dengan larutan Bouin, kemudian diproses dengan diembedding menggunakan parafin. Potongan jaringan selanjutnya diwarnai secara imunohistokimia menggunakan antibodi monoklonal Cu,Zn-SOD. Hasil yang diperoleh menunjukan bahwa ekstrak etanol biji mahoni mampu meningkatkan berat badan, menurunkan konsumsi pakan dan kadar glukosa darah, serta mempertahankan kandungan antioksidan Cu, Zn-SOD baik di pulau Langerhans maupun di sel-sel asinar jaringan pankreas tikus DM.
Keyword: antioksidan Cu, Zn-SOD, diabetes melitus, imunohistokimia, pankreas, mahoni

Judul: Pengaruh Pemberian Ekstrak Etanol Biji Mahoni (Swietenia mahagoni Jacq.) Terhadap Profil Sel β Pankreas pada Tikus Diabetes Mellitus.
Abstrak: The aim of this research was to analyze the effect of ethanol mahogany seeds extract on body weight, total feed consumtion, blood glucose level, the number of beta cells and the islets of Langerhans in the pancreatic tissue of diabetic rats.This study used 25 male rats (Sprague Dawley). The rats were divided into 5 groups: (i) negative control group (K-), (ii) positive control group/diabetes mellitus (DM) (K+), (iii) DM group that was treated with 500 mg/kgBW of the ethanol mahagony seeds extract (EM), (iv) DM group that was treated with acarbose (KO), and (v) non DM group that was treated with 500 mg/kgBW of the ethanol mahagony seed extract (KE). DM condition was obtained by alloxan induction (110 mg/kgBW). The treatments were done for 28 days. Body weight, total feed intake, and blood glucose level were measured during the treatments. At the end of treatments, the pancreas tissues were then obtained and analyzed for the number of beta cells. This study showed that ethanol Swietenia mahagony seeds extract increased body weight, decrease blood glucose level and inhibit the rate of pancreatic β cells damage in the experimental diabetic rats.
Keyword: Mahogany seed extract, diabetes mellitus, beta cells, islets of Langerhans, rats

Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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