Judul: Hubungan Keterdedahan Penonton Dengan Efek Tayangan "Talas Bogor" Megaswara TV (MGS TV). (Kasus RW 12, Kampung Padasuka, Kecamatan Bogor Tengah, Kelurahan Gudang. Kota Bogor. Jawa Barat)
Abstrak: ujuan penelitian ini adalah untuk mengetahui dan menganalisis: (1) hubungan karakteristik individu dengan paparan penonton “Talas Bogor”, (2) the hubungan karakteristik narasumber dengan paparan khalayak “Talas Bogor”, (3) hubungan terpaan penonton dengan efek “Talas Bogor”. Eksposur penonton acara “Talas Bogor” yang tinggi di antaranya antara lain frekuensi menonton dan durasi menonton televisi. Paparan penonton adalah dipengaruhi oleh karakteristik individu, terdiri dari usia, jenis kelamin, pendidikan tingkat, status pekerjaan, dan jenis pekerjaan. Diantara ciri-ciri tersebut ada Dua variabel yang berhubungan dengan paparan khalayak adalah tingkat pendidikan frekuensi dan durasi menonton televisi. Selain individu Karakteristik Terdapat karakteristik yang dapat mempengaruhi sumber paparan, yaitu daya tarik pemateri dan daya tarik narasumber. Namun di antara variabel-variabel tersebut, hanya ada satu variabel nyata yang terkait dengan keterpaparan penonton, yaitu daya tarik menonton pembicara dengan tingkat frekuensi paparan yang tidak berhubungan dengan audiens sebenarnya dampak dari “Talas Bogor”. Pengaruhnya meliputi tingkat pengetahuan responden terhadap isi pesan dan perasaan sikap responden untuk menunjukkan “Talas Bogor”.
Keyword: Audience Exposure, Television, Individual Characteristics, Source Characteristics, Effects

Judul: Motivasi dan Perilaku Menonton serta Penilaian Khalayak Terhadap Program Acara Televisi Lokal (Kasus Pemirsa Megaswara TV di RW 01 Kelurahan Bojong Rangkas, Kecamatan Ciampea, Kabupaten Bogor dan RW 17 Kelurahan Tegal Gundil Kecamatan Bogor Utara, Kota Bogor)
Abstrak: Megaswara TV has known well as the only local television in Bogor. The purpose of this research is to describe the motivation for people to watch Megaswara TV programs and the factors that influence it, finding corelation between motivation and people behaviour in watching the Megaswara TV programs, to describe the people behaviour in watching the Megaswara TV programs and the factors that influence it, and to describe judgement from people who watch the program in Megaswara TV. This research held in two places, one held in Bojong Rangkas village RW 01, Ciampea subdistrict and the other one held in Tegal Gundi village RW 17,Nort Bogor subdistrict, West Java Province. This research using quantitative methode and support by qualitative data. This research give us some results that shown some correlations between several factor which affect people to watch Megaswara TV, these correlation are between level of education with the information motivation, between etnic with personal identity motivation, between family influence with integration and social interaction motivation, between integration and social interaction motivation with the frequency and how long can people watch the show, between entertainment motivation with integration and social interaction motivation, between personal identity motivation with the frequency and how long can people watch the show, between information motivation with how long can people watch the show, between age with watching frequency to fill personal identity needs, between education level with show option and watching duration to fill personal identity needs, between etnic with show option to fill personal identity needs, between age with watching frequency to fill integration and social interaction needs, between education level with show option to fill entertainment needs, between age with watching frequency to fill entertainment needs, between hometown with integration and soial interaction motivation, between hometown with watching frequency to fill entertaiment needs. It is more likely to say that most correspondend have a good judgement for the Megaswara TV shows, not just for the show it self, but the local content, the presenter, the quality of the broadcast, the broadcast time, the benefits, and the actual effects get good credits from most correspondend. Keywords: local television, tv watching behaviour, tv watching motivation
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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