Judul: An Analysis of Changing on Greenery Open Space Area and Factors Influence It In South Jakarta
Abstrak: South Jakarta is one of region in DKI Jakarta facing an enormous growth in all aspects of development. The increasing of development activities and regional cause increase land uses dynamic. Fixed land supply compare with the increasing demand causing land use change particularly greenery open space in South Jakarta. This research aims are: (1) to identify changing of greenery open space of South Jakarta, and (2) to find out population, infrastructure, and development growth rate of South Jakarta; and (3) to identify factors influencing change of greenery open space and relationship among the factors. The result shows that greenery open space in the period of 2002-2007 decreased about 362,21 hectare from 1299,22 hectares in 2002 to 937,01 hectares in 2007. In the same period population and population density increased 0,7% per year while immigrants declined -23% per year. The region of South Jakarta in 2003 showed hierarchy III village was dominant (43 villages), while number of hierarchy II and I village was 17 villages and 5 villages. In 2006 number of village categorized on hierarchy II showed increasing to be 19 villages while hierarchy III decreasing to be 41 villages and hierarchy I was constant in number. Regional development could be due to growth on infrastructure development such as educational facility, health facility, and commercial area. The number of educational, health, and commercial facilities grew during the period of 2003- 2006 with rate 4,8%, 7,1%, and 20% per year, respectively. Regression analysis was utilized to identify factors influencing greenery open space area change. According to the result, land allocated for greenery open space in Jakarta’s spatial plan (RTRW) being the major factor affecting the change. The other factors were growth of health facilities, immigrants, population density, and educational facilities.
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Judul: Analysis of Green Open Space in East Jakarta
Abstrak: Ruang Terbuka Hijau (RTH) berfungsi untuk menjaga kestabilan lingkungan dalam suatu kota. Selain aspek lingkungan, RTH juga berpengaruh terhadap aspek lainnya yaitu aspek sosial, ekonomi maupun keestetikaan sebuah kota. Jakarta Timur merupakan salah satu wilayah administrasi yang menyumbangkan persentase relatif kecil bagi total RTH di DKI Jakarta, belum memenuhi batas minimum luas, sehingga rencana pengembangan RTH di lokasi ini secara strategis perlu direncanakan. Penelitian ini bertujuan untuk mengetahui tingkat perkembangan hirarki setiap kecamatan di Jakarta Timur menggunakan analisis skalogram, mengetahui kebutuhan dan kecukupan RTH Jakarta Timur, mencari faktor-faktor yang berpengaruh terhadap luas RTH di Jakarta Timur dengan analisis regresi berganda dan mengetahui prioritas kecamatan di Jakarta Timur yang berpotensi untuk dilakukan peningkatan RTH dengan aplikasi metode AHP. Hasil penelitian menunjukkan bahwa Kecamatan dengan perkembangan yang paling baik adalah Kecamatan Pulo Gadung yang ditandai dengan jumlah hirarki 1 yang terbanyak yaitu sebanyak tiga kelurahan. Selain itu tidak ada keseragaman dalam pola perkembangan hirarki setiap wilayah. Kebutuhan RTH di Jakarta Timur berdasarkan luas wilayah 3.760,6 ha. Selanjutnya berdasarkan jumlah penduduk pada tahun 2018, kebutuhan RTH adalah seluas 6.259,13 ha. Selain itu, faktor yang dianggap berpengaruh positif terhadap penambahan luas RTH di Jakarta Timur adalah fasilitas kesehatan. Berdasarkan hasil wawancara kepada akademisi maupun praktisi, aspek fisik dan lingkungan paling utama untuk dipertimbangkan dalam rencana pengembangan RTH di Jakarta Timur., Green Open Space serves in maintaining environmental stability of a city. In addition to environmental conditions, Green Open Space affects other aspects, namely social, economic and aesthetic of a city. East Jakarta as one of the capital areas has a small percentage of green spaces, not meeting the minimum acreage, therefore green space development needs to be planned strategically. This study aims to identify the level of hierarchical development of each sub-district in East Jakarta using scalogram analysis, to determine the need and adequacy status of East Jakarta's Green Space, find factors that affect the area of Green Open Space in East Jakarta with multiple regression analysis and to suggest the priority sub-districts in East Jakarta that have the potential to increase Green Open Space with the application of the Analytic Hierarchy Process. The results showed that the best development is observed in Pulo Gadung sub-district which is characterised by more villages identified as hierarchy 1 than other sub-districts, viz three villages. In addition, there is no uniformity in the hierarchical development pattern of each region. The need for green spaces based on area in East Jakarta is 3,760.6 ha, while based on population in 2018 it requires 6,259.13 ha. Moreover, a factor having a positive effect on the addition of green space is health facilities. It seems that academics and practitioners consider physical and environmental aspects as the most essential factor in considering the development of the Green Open Space in East Jakarta.
Keyword: AHP, Adequacy of Green Open Space, Regional Development, Green Open Space

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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