Judul: The Effect of Extract Black Cummin (Nigella sativa) Oil Commercial Product on The Female Reproduction Organ of Mice (Mus musculus).
Abstrak: Jintan hitam (Nigella sativa) secara tradisional digunakan sebagai obat herbal yang sedang popular. Tujuan penelitian kali ini adalah untuk mengetahui efek jintan hitam terhadap histopatologi organ reproduksi betina mencit. Mencit betina umur empat minggu sebanyak 36 ekor dibagi menjadi empat kelompok, yaitu kelompok I diberikan aquades 0,1 ml, kelompok II diberikan 0,1 ml ekstrak minyak jintan hitam, kelompok III diberikan 0,2 ml ekstrak minyak jintan hitam, dan kelompok IV diberikan kombinasi ekstrak minyak jintan hitam dengan madu sebanyak 0,3 ml. Mencit diberikan perlakuan satu kali sehari selama dua bulan. Setelah dua bulan perlakuan, dilakukan nekropsi untuk mendapatkan ovarium dan uterus. Selanjutnya organ diproses untuk histopatologi dengan pewarnaan Hematoksilin-Eosin dan Periodic Acid Schiff. Paramater yang diamati terdiri dari luas ovarium dan folikel tersier; jumlah folikel ovarium, kelenjar uterus, dan sel Goblet; dan regenerasi epitel permukaan uterus. Hasil yang didapatkan menunjukkan bahwa jintan hitam meningkatkan kinerja ovarium dan perbaikan homeostasis uterus. Kesimpulan dari penelitian ini yaitu jintan hitam memberikan efek terhadap sistem reproduksi betina mencit.
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Judul: Pengaruh Pemberian Ekstrak Minyak Jintan Hitam (Nigella sativa) terhadap Gambaran Histologi Organ Lambung dan Usus Halus Mencit (Mus musculus)
Abstrak: Habatussauda or black cumin seed (Nigella sativa) is a popular herbal medicine worldwide. The aim of this research was to observe histology changes on stomach and small intestine of mice treated with Nigella sativa oil extracts. Seventy two 4-week-old mice, consisting of thirty six male and female, were divided each into four groups. Group 1 (control) were treated with 0.1 ml of aquadest, group 2 with 0.1 ml of N. sativa oil extract, group 3 with 0.2 ml of N. sativa oil extract, and group 4 with 0.3 ml of combined N. sativa oil etxract and honey. All treatment were done orally everyday for two months period. Afterwards, mice were euthanized by atlanto-occipitale dislocation for organs sampling. Stomach and small intestine were fixed in 10% Buffered Neutral Formaline (BNF), embedded in paraffin, then stained with haematoxylin and eosin (HE) and periodic-acid schiff (PAS). The results showed that N. sativa treatment significantly increased (P<0.05) the number of parietal and chief cells, and reduced the number of mucous cells and infiltrating inflammatory cells in stomach; while, increased height of villi, increased number of crypts, reduced number of inflammatory cells, and reduced number of goblet cells were observed in small intestine, as compared with those in control. Additionally, there were no significant differences (P>0.05) in all parameters between male and female mice. These data may suggest cell protection and inflammatory cells suppresion activities of N. sativa treatment in gastrointestinal tracts.
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Judul: Penyelesaian Stacker Crane Problem dengan Algoritme Largearcs dan Smallarcs
Abstrak: In graph theory, the Rural Postman Problem (RPP) aims to determine the shortest route with minimum cost, in which only certain edges or arcs are necessarily traversed. One type of RPP is Stacker Crane Problem (SCP) which deals with a mixed graph but only arcs are necessarily traversed. SCP can be solved by using two heuristic algorithms, i.e. Largearcs and Smallarcs algorithms, which include other algorithms in their steps, such as: Dijkstra algorithm to determine shortest route, Hungaria method to determine minimum bipartite matching, Prim algorithm to determine minimum spanning tree, and van Aardenne-Ehrenfest & de-Bruijn algorithm and Fleury algorithm to determine Euler circuits. The shortest Euler circuit resulted from two heuristic algorithms can be used to find a solution of SCP. The application of SCP is illustrated in establishing the minimum distance route of catering delivery.
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