Judul: Durability of Specific Immunoglobulin (Ig) Y Againts Influenza and Covid-19 in Sunscreen
Abstrak: The benefit of specific immunoglobulin Y (Ig Y) as an active ingredient in personal care products such as sunscreen has not been properly studied. Our study aims to evaluate the reliability of specific IgY against influenza and the COVID-19 virus in a sample sunscreen product. Specific IgY influenza and COVID-19 viruses were inserted in the sample sunscreen at two concentrations of 0.1% and 0.25%. Three treatments were observed: control (C) sunscreen without IgY, treatment 1 (T1) sunscreen with 0.1% IgY, and treatment 2 (T2) sunscreen with 0.25% IgY. Organoleptic observations were carried out to monitor changes in aroma, color, and texture, and sunscreen sampling was done every week for 6 weeks. The durability of IgY was evaluated using an enzyme-linked immunosorbent assay (ELISA) and a neutralization assay. Organoleptic observation from weeks 1 to 6 showed consistency in its aroma, color, and texture. Enzyme-linked immunosorbent assay and neutralization assay (NA) results of the T1 and T2 groups showed negative results except for sample T1 at week 5, which showed a positive result in the Influenza A ELISA. Based on the results, it seems that IgY concentrations of 0.1% or 0.25% were not optimal. However, this negative result might be due to low concentration of the IgY and the presence of beeswax, which inhibits IgY and causes it to dissolve in distilled water, thus preventing it from being detected in the assay.
Keyword: Immunoglobulin Y, Sunscreen, Influenza, COVID-19, Biological Activity

Judul: Daya Tahan IgY Spesifik Terhadap Influenza dan COVID-19 dalam Balsam Bibir
Abstrak: Influenza and SARS-CoV-2 virus are respiratory infections and require antiviral medications due to severe consequences. Utilization of specific immunoglobulin Y (IgY) inserted in personal care products were developed. The aim of this study was to evaluate durability of specific IgY against influenza and COVID-19 in lipbalm. The concentration of IgY used in this research was 0.1% and 0.25%. Three groups were observed: control (C) lipbalm without IgY, treatment 1 (T1) lipbalm with 0.1% IgY and treatment 2 (T2) lipbalm with 0.25% IgY. Organoleptic tests were conducted and recorded which includes the sense of smell, colour and consistency for six weeks. The presence of IgY in lipbalm was evaluated using enzyme-linked-immunosorbent-assay (ELISA) and neutralizationassay. There were some noticeable changes of organoleptic that can be observed such as colour darkened and texture hardened of the lipbalm. Most of the assays gave negative results in T1 and T2, whilst only few of them were doubtful. Our result indicated that IgY concentration of 0.1% or 0.25% in lipbalm were not optimal. However, the negative result might be due to the unavailability of IgY in the product to be dissolved in deionized water since we used beeswax as lipbalm component.
Keyword: Covid-19, egg yolk immunoglobulin Y, lipbalm, influenza

Judul: Cycle Hamilton pada Graf Lengkap, Graf Regular, dan Graf 2-Connected 4-Regular Berorder Kurang dari Sepuluh.
Abstrak: Suatu graf disebut graf Hamilton apabila graf tersebut memuat cycle Hamilton, yaitu cycle yang melewati setiap vertex tepat satu kali. Menentukan keberadaan cycle Hamilton pada suatu graf dapat menggunakan syarat cukup yang berupa teorema-teorema yang telah diperkenalkan sejak tahun 1950-an. Beberapa syarat cukup yang dibahas dalam karya ilmiah ini adalah syarat cukup yang berhubungan dengan graf lengkap dan graf regular. ,,,
Keyword: graf Hamilton, graf regular, graf lengkap, graf 2-connected 4-regular.