Judul: Histomorfologi tubulus seminiferus dan kelenjar prostat tikus (Rattus Norvegicus) serta konsentrasi hormon androgen pasca pemberian ekstrak purwoceng (Pimpinella Alpina Molk.)
Abstrak: Indonesia is one of the countries which has many kinds of herbal plants. Pimpinella alpina Molk. well known as purwoceng is one of Indonesian herbal plants which have aphrodisiaca actions may enhance libido in males. Moreover, it has been reported that an increase the levels of LH (lutheinizing hormone) and testosterone in blood serum of male rats given the purwoceng extract. The increase of the LH and testosterone level thought to affect the primary and secondary organs in males and level of androgens hormones (testosterone and dihydrotestosterone or DHT). The objective of these experiment was to determine the spermatogenesis, prostate glands activity and the production of androgen hormone (testosterone and DHT) of rats after given of purwoceng extract and it influence of dose and age. The treatment were given orally for 14 days in three age groups (puberty, adult and old) of male rats by received the dose of 25 mg and 50 mg and 0 mg as control. The results shows an increase of the stage of spermatogenesis in the seminiferous tubules after all age groups received purwoceng extract with 50 mg dose of purwoceng was the best since it had the highest response. In addition, these experiment shows there has been an increase of the percentage of prostate glands activity producing prostate fluid. The animals who received the 50 mg purwoceng extract showed the highest response at any age. The effect of the purwoceng extract on the concentrations of androgens (testosterone and DHT) was higher and lower in some age group, but has not perfomed significant effects (p> 0.05). In conclusion of these experiment shows the stage of spermatogenesis, prostate glands activity and the production of androgen hormones increases at all ages, while at the age of puberty the DHT hormone production decreases after giving purwaceng extract.
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Judul: Study of Androgenic Effect of Ethanolic Extract of Root Purwoceng (Pimpinella alpina KDS) on the Reproduction Performance of Adult Female Rats (Rattus norvegicus)
Abstrak: which had been used in male reproductive research because it has androgenic property. Studies of purwoceng on female reproductive performance is not clearly yet. This research was conducted to explore the effect of purwoceng on duration of each period and total time of estrus cycle. A total of 48 female rats strain of Sprague Dawley were divided into 4 groups based on their estrous period: proestrus, estrus, metestrus and diestrus. Each group consisted of 6 rats as a control and 6 rats as treated animals. Extract of purwoceng was given oraly every day for 10 days. After 10 days, half of them were sacrificed and the rest of group were continued for vaginal smears examination until day 15. The results showed that purwoceng given at various periods during 2 cycles of estrous extend the time period of proestrus and estrus, and significantly different in estrous period when given during the period of estrus (P<0.05) compare to other period. Time period of metestrus and diestrus were decreased except period of metestrus which increased during administration of purwoceng on metestrus. The weight of uterine and ovarian was higher on rats receiving purwoceng during estrus period than the control (P<0.05). The conclusion of this research was that the administration of purwoceng was more effective when it was given at times of estrus period.
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Judul: Formulasi Hamiltonian untuk Menggambarkan Gerak Gelombang Soliter Dimensi Tiga di Permukaan Laut
Abstrak: Gelombang permukaan adalah gelombang yang terjadi perbedaan rapat massa antara air dan udara. Salah satu gelombang permukaan yang ditinjau adalah gelombang soliter. Formulasi gelombang soliter dilakukan dengan menggunakan formulasi Hamiltonian.
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