Judul: Isolasi Fraksi Aktif Ekstrak Daun Dandang Gendis (Clinacanthus nutans) Berpotensi sebagai Antibakteri
Abstrak: Ethanol extract of dan dang gendis leaves have been known to be toxic toward Artemia salina brine shrimp. This toxicity property was likely due to the existences of some of its secondary metabolites that have antibacterial properties. Hence, this plant could be used as a substitute of the synthetic drugs usage. The purpose of this study was to find the most active fraction of ethanol extracts of dandang gendis leaves as a potential antibacterial and to determine the group of the active compound. The ethanol extract was fractionated using flash chromatography with silica gel as the stationary phase and ethyl acetate: n-hexane (8:2) as the 1110bile phase resulted in total of four fractions (fraction I to 4). Then the capability of those fractions, to inhibit the growth of two types of bacteria, Escherichia coli and Staphylococcus aZlreliS was tested. Fractions I with concentration of 1000 ppm had the largest inhibitory zone with the area of 4.17 and 7 mm in diameter when it was tested on E. coli and S. aureus respectively. The formation of inhibitory zone showed that fraction I of the ethanol extract of danclang gendis to have a weak antibacterial effect toward E. coli and moderate effect (5-10 Illm) on S. aureus. Based on the phytochemical assay, fraction 1 showed positive result on steroid and flavonoid tests
Keyword: 

Judul: Optimisasi Ekstraksi Cair-Cair Fraksi Etanol Daun Dandang Gendis (Clinacanthus nutans)
Abstrak: Dandang gendis (Clinacanthus nutans) is a herb which contains antimalaria and larvacide bioactive compounds. In this study, the dried leaf powder was macerated with ethanol and then partitioned with n-hexane. The resulting ethanol extract was then partitioned again with ethyl acetate and this liquid-liquid extraction procedure was the subject of the optimization. Sample to solvent ratio (1:2, 1:3, and 1:4 (mL/mL), extraction temperature (30, 40, and 50 °C); and extraction repetition (1, 2, and 3 times) variations effect were studied. The bioactivity of the extracts were tested with brine shrimp lethality test (BSLT) using Artemia salina. The BSLT result of the 11th extract showed the optimum LC50 value (59.15 mg/L). This extract was obtained from the extraction procedure using 1:4 (mL/mL) sample to solvent ratio, 40 °C temperature, and 3 times repetition. From the Minitab 15 computation results were predicted that the optimum condition is achieved at 1:3.88 – 1:4.00 (mL/mL) sample to solvent ratio, 4.61 – 49.99 °C extraction temperature, and 3 times extraction repetition with LC50 170.19 mg/L. The phytochemistry test results showed that the 11th extract contains alkaloids, flavonoids, saponins, and steroids.
Keyword: 

Judul: Pengaruh Tekanan Ekonomi dan Penyesuaian Perkawinan terhadap Kepuasan Perkawinan Keluarga yang Menikah Muda
Abstrak: Pernikahan adalah ikatan lahir batin antara pria dan wanita sebagai suami istri dengan tujuan membentuk keluarga yang bahagia atau kekal berdasarkan Ketuhanan yang Maha Esa. Pernikahan muda adalah pernikahan yang dilakukan pasangan yang menikah di bawah usia 20 tahun. Penelitian ini bertujuan untuk mengetahui pengaruh tekanan ekonomi dan penyesuaian perkawinan terhadap kepuasan perkawinan keluarga yang menikah muda. Penelitian ini melibatkan 60 keluarga yang dipilih secara snowball dengan istri sebagai contoh. Analisis data menggunakan uji deskriptif, uji korelasi, dan uji regresi berganda. Hasil penelitian menunjukkan adanya hubungan negatif signifikan antara tekanan ekonomi obyektif dengan kepuasan perkawinan. Hasil penelitian juga menunjukkan adanya pengaruh positif signifikan antara besar keluarga, tekanan ekonomi subyektif, dan penyesuaian perkawinan terhadap kepuasan perkawinan serta pengaruh negatif signifikan antara tekanan ekonomi obyektif dengan kepuasan perkawinan.
Keyword: kepuasan perkawinan, menikah muda, penyesuaian perkawinan, tekanan ekonomi