Judul: OKE Garden Landscaping Business Development Strategy
Abstrak: Belakangan ini startup berkembang pesat di Indonesia.Minat berkebun dan permintaan akan tukang taman yang meningkat menuntut adanya startup di bidang pertamanan. Peluang ini dimanfaatkan oleh OKE Garden untuk melayani kebutuhan pertamanan masyarakat di seluruh wilayah Indonesia. Penelitian ini bertujuan untuk memetakan model bisnis yang digunakan OKE Garden, merumuskan alternatif strategi pengembangan bisnis, serta pembaruan Businness Model Canvas. Metode yang digunakan adalah analisis kualitatif deskriptif berupa wawancara mendalam dan diskusi dengan pihak internal yang ahli di bidangnya serta observasi langsung. Setelah dilakukan penelitian, didapatkan bahwa OKE Garden menjalankan model bisnis startup yang menawarkan digitalisasi pelayanan jasa pertamanan. Berdasarkan analisis SWOT yang telah dilakukan terhadap kesembilan elemen Business Model Canvas pada OKE Garden, ditemukan kelemahan pada kesembilan elemen model bisnis. Oleh sebab itu pembaruan Business Model Canvas dilakukan untuk kesembilan elemen model bisnis agar meningkatkan daya saing OKE Garden di industri pertamanan., Recently, startups have been growing rapidly in Indonesia. The interest in gardening and the increasing demand for gardeners demands startups in the field of landscaping. This opportunity is used by OKE Garden to serve the landscaping needs of people in all parts of Indonesia. This study aims to map the business model used by OKE Garden, formulate alternative business development strategies, and update the Business Model Canvas. The method used is descriptive qualitative analysis in the form of in-depth interviews and discussion with internal parties who are experts in their fields and direct observation. After conducting research, it was found that OKE Garden runs a startup business model that offers digitization of gardening services. Based on the SWOT analysis that was carried out on the nine elements of the Business Model Canvas at OKE Garden, weaknesses were found in the nine elements of the business model. Therefore, an update of the Business Model Canvas was carried out for the nine elements of the business model in order to increase OKE Garden's competitiveness in the gardening industry.
Keyword: business model canvas, development strategy, OKE Garden, SWOT matrix

Judul: Strategi Pengembangan Inti Agrowisata dengan Pendekatan Business Model Canvas.
Abstrak: Inti Agrowisata merupakan salah satu perusahaan agrowisata di Kota Bogor yang menawarkan sarana rekreasi berbasis edukasi pertanian. Saat ini, agrowisata ini masih kurang berkembang, yang ditandai dengan tingkat kunjungan wisata yang rendah. Oleh karena itu, perusahaan berupaya untuk melakukan pengembangan dalam bisnis tersebut. Penelitian ini bertujuan untuk mengidentifikasi model bisnis saat ini, mengevaluasi dan merancang perbaikan model bisnis baru dengan pendekatan model bisnis kanvas. Responden dalam penelitian ini adalah 3 orang dari pihak internal Inti Agrowisata, yaitu manajer umum, manajer produksi, dan manajer keuangan. Metode analisis bersifat kualitatif, yang terdiri atas analisis deskriptif dan analisis SWOT. Analisis deskriptif diolah berdasarkan elemen model bisnis kanvas. Penelitian ini menghasilkan model bisnis yang sedang berjalan dan perbaikan model bisnis berdasarkan rumusan strategi. Strategi yang dihasilkan menciptakan proposisi nilai baru yaitu pengemasan agrowisata dengan icon jambu kristal, disertai perbaikan fasilitas, kualitas pelayanan, dan aktivitas manajerial.
Keyword: agrowisata, strategi, model bisnis kanvas, SWOT

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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