Judul: Utilization of chitosan from crustacean waste as wound healing at mice (Mus musculus albinus)
Abstrak: Crustacean shell contain an organic substance called chitin, that can be transform into chitosan. This research used crab shell as the crustacean waste. This research focused on to know the influence of chitosan applied to wound healing process on male mice skin with macroscopic observation parameters such as size of wound, dryness of wound, and condition of granulation tissue also other parameter in histopathology observation such as inflammation cell infiltrate, neocapilarization, re-epitelization, and forming of connective tissue. Twenty seven mice were divided into 3 groups. Groups 1 (negative control), group II (positive control, Betadine®), and group III (chitosan). Wounding done by wounding the back fairish using scapel measuring 5x5 mm2. Betadine® and chitosan solution were applied every two times a day for 6 day. Observation and take skin sample were conducted at 0th, 2nd, 4th, and 6th day after wounding at 3 mice from each group. Statistically, chitosan have the ability speed up process of wound healing because it􀂶s significantly different compared to negative control.
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Judul: Pengaruh Pemberian Salep Fraksi Etil Asetat Rimpang Kunyit (Curcuma longa Linn.) terhadap Persembuhan Luka Mencit (Mus musculus albinus) Hiperglikemik
Abstrak: The aim of this research was to know the effect of turmeric (Curcuma linga Linn.) etil asetat fraction ointment in wound healing of hiperglicemic mice (Mus musculus albinus). Thirty mice were infected with 40 mg/kgbw of streptozotocin to induced hiperglicemic. Mice were divided into three groups, which were negative control without treatment, positive control was treated with the comersil ointment and the group with the etil asetat turmeric rhizomes fraction ointment treatment. Mice were wounded by scalpel blade on the their dorsoanterior skin of mice around 1.5 cm. The pathology-anatomy of the wound healing procces were observed everyday with wound size, wound colour, wound exudation, and scab formation as the parameter. The histopathology lesion were observed on the 2nd, 4th, 7th, 14th, and 21th days after skin incision. The parameter on the histopathology observation are number of polymorfonuclear cell (neutrofil), macrophag, neovascullary formation, the precentation of wound reepitelization and the percentation of collagen connective tissue. The histopathology observation of etil asetat turmeric rhizomes fraction ointment had anti inflamantory activity as well as neovascularization and reepithelization were faster than the other groups.
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Judul: Cycle Hamilton pada Graf Lengkap, Graf Regular, dan Graf 2-Connected 4-Regular Berorder Kurang dari Sepuluh
Abstrak: Suatu graf disebut graf Hamilton apabila graf tersebut memuat cycle Hamilton, yaitu cycle yang melewati setiap vertex tepat satu kali. Menentukan keberadaan cycle Hamilton pada suatu graf dapat menggunakan syarat cukup yang berupa teorema-teorema yang telah diperkenalkan sejak tahun 1950-an. Beberapa syarat cukup yang dibahas dalam karya ilmiah ini adalah syarat cukup yang berhubungan dengan graf lengkap dan graf regular. Suatu graf lengkap berorder 𝑛������ ≥ 3 dan graf r-regular berorder 𝑛������ ≤ 2𝑟������ + 1 merupakan graf Hamilton, Karena kedua graf tersebut memuat cycle Hamilton. Selanjutnya, syarat cukup tersebut digunakan untuk menentukan keberadaan cycle Hamilton pada graf 2-connected 4- regular berorder kurang dari 10.
Keyword: graf Hamilton, graf regular, graf lengkap, graf 2-connected 4-regular