Judul: Landscape Designing a Neighborhood Park in  Flats Paspampres, IKN Nusantara, East Kalimantan
Abstrak: Sepaku, Kalimantan Timur ditetapkan menjadi IKN karena aksesibilitas lokasi yang tinggi, berada di sekitar dua kota besar, struktur kependudukan heterogen, potensi konflik rendah, pertahanan didukung oleh Tri Matra Darat, Laut, Udara, dan infrastruktur utama lengkap. Pembangunan yang pesat akan mendorong peningkatan kebutuhan hunian vertikal yang cerdas serta ruang terbuka hijau untuk mengurangi emisi gas rumah kaca bagi para Aparatur Sipil Negara serta masyarakat umum. Desain lanskap ini memanfaatkan lahan terbuka sebagai taman lingkungan di rusun Paspampres. Taman lingkungan adalah salah satu ruang terbuka hijau yang berperan penting sebagai media beraktivitas di ruang terbuka bagi penduduk, selain memberi fungsi sosial, ekologis dan fungsi penting lainnya. Tujuan dari penelitian ini yaitu mengidentifikasi dan menganalisis lanskap Rusun Paspampres serta menghasilkan desain lanskap taman lingkungan berbasis konsep biomimicry pada rusun Paspampres. Metode yang digunakan dalam penelitian ini yaitu metode deskriptif mengacu pada tiga pendekatan yaitu fisik-biofisik, sosial, dan legal. Data diambil melalui survei dan studi literatur. Tahapan penelitian dilakukan mulai dari Project Acceptance, Research/Analysis, Design, and Constructional Drawing. Desain menggunakan pola desain dari transformasi bentuk pohon hayat pada logo IKN sehingga menghasilkan 4 ruang yaitu ruang penerimaan, rekreasi, pendukung dan religi. Topografi tapak yang menyebabkan genangan air dimanfaatkan sebagai embung untuk konservasi air dan pengendali iklim mikro. Desain lanskap taman lingkungan diharapkan menjadi bahan acuan bagi pemerintah dan pengelola dalam pengembangan ruang terbuka hijau., Sepaku, East Kalimantan has been designated as the new capital city (IKN) due to its high accessibility, proximity to two major cities, heterogeneous population structure, low potential for conflict, and defense supported by the Tri Matra of Land, Sea, and Air forces. Additionally, the area is equipped with complete main infrastructure. Rapid development in this area drives the need for smart vertical housing and green open spaces to reduce greenhouse gas emissions for civil servants and the general public. This landscape design utilizes open land as an environmental park in the Paspampres apartments. Environmental parks are one of the green open spaces that play an important role as a medium for outdoor activities for residents. Besides that, they also provide social, ecological, and other important functions. The aim of this research is to identify and analyze the landscape of the Paspampres apartments and produce an environmental park landscape design based on the concept of biomimicry in the Paspampres apartments.The method used in this research is a descriptive method referring to three approaches: physical-biophysical, social, and legal. Data was collected through surveys and literature studies. The research stages were carried out from Project Acceptance, Research/Analysis, Design, and Construction Drawing. The design uses a pattern from the transformation of the tree of life shape on the IKN logo, resulting in four spaces: reception, recreation, support, and religious spaces. The site's topography, which causes water pooling, is utilized as a reservoir for water conservation and microclimate control. The environmental park landscape design is expected to serve as a reference for the government and managers in developing green open spaces.
Keyword: Landscape Design, Flats, Green Open Spaces, IKN Nusantara, Neighborhood Park

Judul: The Landscape Design of  Labuhanbatu Selatan Government Office Based on Eco-Design
Abstrak: Kabupaten Labuhanbatu Selatan merupakan sebuah kabupaten di Sumatera Utara yang baru dimekarkan pada tahun 2009 dan saat ini masih dalam tahap perkembangan dan pembangunan daerah. Perkembangan yang cepat sejalan dengan banyaknya lahan yang dibuka untuk pemukiman, perkebunan, dan juga perkantoran pemerintah. Banyaknya pembangunan mengakibatkan banyak Ruang Terbuka Hijau (RTH) yang hilang. Oleh karena itu diperlukannya sebuah RTH publik yang dapat menyeimbangkan ekosistem maupun untuk area yang dapat dimanfaatkan masyarakat. Area perkantoran pemerintah kabupaten Labuhanbatu Selatan adalah salah satu area yang dapat dimanfaatkan untuk dijadikan taman kota. Penelitian ini bertujuan untuk membuat konsep desain dan mendesain lanskap perkantoran pemerintah kabupaten Labuhanbatu Selatan. Penelitian ini dilakukan dengan menggunakan metode deskriptif, melalui survey lapang dan penyebaran kuisioner yang akan dilakukan dalam empat tahapan, yakni tahap persiapan, pengumpulan data, pengolahan data (konsep, analisis, dan sintesis), dan desain. Hasil penelitian ini berupa site plan, gambar potongan, dan gambar perspektif. Konsep dasar dari tapak penelitian ini adalah “Eco public park” yaitu taman ekologis yang diperuntukkan bagi berbagai kelompok masyarakat. Konsep ini memberikan alternatif bagi masyarakat untuk melakukan kegiatan rekreasi seperti berkumpul, bersantai, bermain, berolahraga, serta jalan-jalan menikmati pemandangan dengan lingkungan yang nyaman. Konsep desain mengimplementasi bentuk dari ranting dan cabang pohon karet. Bentuk dari ranting dan cabang pohon karet ditransformasi menjadi garis-garis geometris yang akan membentuk pola, ruang, dan pola penanaman pada tapak. Desain pada tapak penelitian akan membagi ruang atau area pada tapak menjadi area penerimaan, area pelayanan, area publik, area bersantai, dan area olahraga., Labuhanbatu Selatan is a regency in North Sumatra which expanded in 2009 and currently under development and regional establishment. The rapid development is in line with the large amount of land cleared for housing area, plantations area, and also area for government offices. The large amount of land cleared caused the loss of Green Open Space. Hence the Green Open Space is needed to balance the ecosystem or areas that can be utilized by the society. The area for government offices of Labuhanbatu Selatan regency is one of the areas that can be used for Green Open Space especially for parks. This study is aim to create a concept design and design a landscape of government offices in Labuhanbatu Selatan regency. This research was conducted using a descriptive method, through a field observation and a questionnaire that distribute in four stages, they are; preparation, data collection, data processing (concept, analysis, and synthesis), and a design. The results of this study are site plan, section drawings, planting plan, and perspective pictures. The basic concept of this research is "Eco public park" which is an ecological park that is usefull for communities. This concept provides an alternative for the community to carry out recreational activities such as gathering, relaxing, playing, exercising, and taking walks to enjoy the scenery in a comfortable environment. The design concept implements the shape of rubber tree branches. The shape of the rubber tree branches is transformed into geometric lines that will form patterns, spaces, and planting patterns on the site. The design on the research site will divide the space or area on the site into welcome area, service
Keyword: Desain Lanskap, Perkantoran Pemerintah, Ruang Terbuka Hijau

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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