Judul: Study About Factors Influencing Transition of Green Open Spaces Based on Analysis of Land Use in Depok City, West Java, Indonesia
Abstrak: This study focused on land development in Depok City located south of Jakarta. Although Depok enjoys a tropical climate, it is necessary to consider the distribution of land use within the city, especially green open spaces. Depok is a commercial center and a public utilities center, where water is stored to supply ground water as buffer city of Jakarta. Moreover, it is a hotspot of education and residential area development. Depok is influenced strongly by land development in Jakarta, and further economic growth is expected. The purpose of this study is to understand the transition of green open spaces and land use types in Depok to reveal the changes in the of area of green open spaces in Depok and to identify the factors influencing the transition of green open spaces in Depok. To identify the factors influencing the transition of green open spaces, binomial logistic regression analysis was used. The dependent variable was the area of green open space converted into non-green open space, and the independent variables included distance from commercial facilities, distance from industrial areas, distance from educational areas, distance from hospitals, distance from rivers, distance from lakes, distance from main roads, distance from a highway, distance from a highway entrance, distance from a railroad station, and distance from inundation-prone areas. It was revealed that the area of green open space has rapidly decreased in Depok, especially from 2005 to 2015. Two factors particularly influenced the transition of green open spaces, where a greater proximity to educational areas or main roads was associated with a greater reduction in green open space. Also, the distance from hospitals and lakes were associated with the maintenance of green open spaces in Depok. For residents, convenience is improved in areas close to educational areas or main roads; therefore, it is conceivable that buildings such as housings are increasing accordingly in such areas. Keywords:binomial logistic regression analysis, green open space, land use
Keyword: Binomial logistic regression analysis, Green open space, Land use

Judul: An Analysis of Changing on Greenery Open Space Area and Factors Influence It In South Jakarta
Abstrak: South Jakarta is one of region in DKI Jakarta facing an enormous growth in all aspects of development. The increasing of development activities and regional cause increase land uses dynamic. Fixed land supply compare with the increasing demand causing land use change particularly greenery open space in South Jakarta. This research aims are: (1) to identify changing of greenery open space of South Jakarta, and (2) to find out population, infrastructure, and development growth rate of South Jakarta; and (3) to identify factors influencing change of greenery open space and relationship among the factors. The result shows that greenery open space in the period of 2002-2007 decreased about 362,21 hectare from 1299,22 hectares in 2002 to 937,01 hectares in 2007. In the same period population and population density increased 0,7% per year while immigrants declined -23% per year. The region of South Jakarta in 2003 showed hierarchy III village was dominant (43 villages), while number of hierarchy II and I village was 17 villages and 5 villages. In 2006 number of village categorized on hierarchy II showed increasing to be 19 villages while hierarchy III decreasing to be 41 villages and hierarchy I was constant in number. Regional development could be due to growth on infrastructure development such as educational facility, health facility, and commercial area. The number of educational, health, and commercial facilities grew during the period of 2003- 2006 with rate 4,8%, 7,1%, and 20% per year, respectively. Regression analysis was utilized to identify factors influencing greenery open space area change. According to the result, land allocated for greenery open space in Jakarta’s spatial plan (RTRW) being the major factor affecting the change. The other factors were growth of health facilities, immigrants, population density, and educational facilities.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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