Judul: Profil Leukosit Sprague Dawley Pascaimplantasi Jangka Panjang Biomaterial Besi (Fe) Berpori pada Defek Os Femur.
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh implantasi jangka panjang biomaterial logam terdegrasi berbahan dasar besi berpori pada tulang femur terhadap gambaran leukosit tikus Sprague Dawley. Sebanyak 60 tikus Sprague Dawley dibagi dalam 4 kelompok. Masing-masing kelompok terdiri atas 15 ekor tikus dengan perlakuan kontrol, implan berpori 450 μm, 580 μm, 800 μm. Ukuran implan adalah panjang 5 mm, lebar 2 mm dan ketebalan 0,5 mm. Implantasi dilakukan pada permukaan os femur. Pengambilan sampel darah dilakukan selama sepuluh bulan pengamatan yaitu pada bulan ke- 2, 4, 6, 8 dan 10 pasca implantasi. Analisis data dilakukan menggunakan aplikasi software Statistical Product and Service Solutions (SPSS®) versi 16.0. Pengujian perbedaan profil darah putih antar kelompok dan waktu perlakuan dilakukan dengan uji one way ANOVA. Uji analisis duncan dilakukan jika hasil uji sebelumnya memiliki nilai P<0,05. Secara keseluruhan, profil leukosit, neutrofil batang, neutrofil segmen, basofil, eosinofil, limfosit dan monosit mengikuti pola fluktuasi yang sama dengan kontrol. Kesimpulan yang diperoleh adalah perlakuan implan besi berpori 450 μm, 580 μm, 800 μm tidak berpengaruh terhadap profil leukosit.
Keyword: implan, besi (Fe) berpori, persembuhan, leukosit

Judul: Profil Eritrosit Tikus Sprague Dawley Pasca Implantasi Biomaterial Besi (Fe) Berpori pada Os Femoris.
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh implantasi biomaterial besi berpori pada os femoris terhadap profil eritrosit tikus Sprague Dawley. Sebanyak 60 ekor tikus Sprague Dawley dibagi dalam 4 kelompok. Masing-masing kelompok terdiri dari 15 ekor tikus dengan perlakuan diameter pori implan 450 μm, 580 μm, 800 μm, dan kelompok kontrol yang tidak ditanamkan implan. Implan ditanamkan pada diafise os femoris. Pengambilan sampel darah dilakukan pada bulan ke-0, 2, 4, dan 6 pasca implantasi secara intra arterial melalui arteri coccygealis. Pemeriksaan profil eritrosit meliputi jumlah eritrosit, nilai hematokrit, kadar hemoglobin, dan indeks eritrosit (MCV, MCHC). Hasil penelitian dianalisis dengan uji one way ANOVA dan uji perbandingan ganda menggunakan program Statistic Program for Social Science (SPSS). Hasil penelitian menunjukkan jumlah eritrosit mengalami peningkatan pasca implantasi biomaterial Fe berpori, sehingga berpengaruh terhadap peningkatan nilai hematokrit dan kadar hemoglobin. Hal tersebut merupakan respon sumsum tulang terhadap perdarahan saat operasi. Hasil ini menunjukkan bahwa implantasi biomaterial Fe berpori tidak menyebabkan reaksi yang berlebihan pada eritrosit. Tidak adanya perbedaan yang nyata (p>0,05) pada nilai MCV dan MCHC menunjukkan bahwa implantasi biomaterial Fe berpori tidak memengaruhi profil eritrosit tikus Sprague Dawley, sehingga memiliki potensi untuk dijadikan alternatif biomaterial implantasi tulang.
Keyword: besi berpori (Fe), biomaterial, Os Femoris, profil eritrosit, tikus

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
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