Judul: Antifungal Activity of Manglid (Magnolia sumatrana (Miq.) Figlar & Noot) Wood Extract
Abstrak: Untuk meningkatkan masa pakai kayu maka perlu dilakukan pengawetan. Namun bahan pengawet yang digunakan pada saat ini banyak yang berasal dari bahan sintetik sehingga membahayakan lingkungan dan kesehatan manusia. Penelitian ini bertujuan untuk menentukan kadar zat ekstraktif kayu manglid (Magnolia sumatrana (Miq.) Figlar & Noot) dan menguji sifat antijamur zat eksttraktif tersebut terhadap jamur pelapuk putih (Schizophyllum commune) dan jamur pelapuk cokelat (Tyromyces palustris), serta mengidentifikasi komponen kimia fraksi teraktif. Serbuk kayu teras manglid diekstraksi menggunakan aseton. Ekstrak aseton yang dihasilkan lalu difraksinasi secara bertingkat dengan n-heksana, etil eter, dan etil asetat. Masing-masing fraksi diuji sifat antijamurnya terhadap jamur pelapuk. Fraksi yang mempunyai sifat antijamur paling aktif selanjutnya diidentifikasi menggunakan GCMS-Pirolisis. Hasil penelitian menunjukkan kadar esktrak aseton kayu teras manglid sebesar 4,75% yang terdiri dari fraksi n-heksana sebesar 0,85%, fraksi etil eter 0,45%, fraksi etil asetat 0,67%, dan fraksi residu sebesar 2,78%. Dari uji antijamur diketahui bahwa fraksi etil asetat memiliki aktivitas antijamur paling tinggi. Dari analisis kimia dengan GCMS diperoleh 4 senyawa dominan yang memiliki sifat antijamur yang diduga berperan dalam menghambat pertumbuhan jamur yaitu Phenol, 2-methoxy- (CAS) Guaiaco; Phenol, 2-methoxy-4-(2-propenyl)- (CAS) Eugenol; Phenol, 2,6-dimethoxy- (CAS) 2,6-Dimethoxyphenol; dan 1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester (CAS) Bis(2-ethylhexyl) phthalate., To increase the service life of wood, it is necessary to preserve it. However, most of the preservatives used today are synthetic materials that are harmful to the environment and human health. This study aimed to determine the extractive content of manglid wood (Magnolia sumatrana (Miq.) Figlar & Noot) and to test the antifungal properties of the extractive against white rot fungus (Schizophyllum commune) and brown rot fungus (Tyromyces palustris), and identify the chemical components of the most active fraction. Manglid wood was extracted using acetone. The resulting acetone extract was then fractionated in stages with n-hexane, ethyl ether, and ethyl acetate. Each fraction was further tested for its antifungal properties against rotting fungi. The most active fraction was then identified using Pyrolysis-GCMS. The results showed that the acetone extract content of manglid hearthwood was 4,75% consisting of n-hexane fraction of 0,85%, ethyl ether fraction of 0,45%, ethyl acetate fraction of 0,67%, and residual fraction of 2,78%. The ethyl acetate fraction had the highest antifungal activity. From chemical analysis by GCMS obtained 4 dominant compounds that have antifungal properties that are thought to play a role in inhibiting fungal growth, namely Phenol, 2-methoxy- (CAS) Guaiacol; Phenol, 2-methoxy-4-(2-propenyl)- (CAS) Eugenol; Phenol, 2,6-dimethoxy- (CAS) 2,6-Dimethoxyphenol; and 1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester (CAS) Bis(2-ethylhexyl) phthalate.
Keyword: antijamur, ekstrak aseton, kayu manglid (Magnolia sumatrana (Miq.) Figlar & Noot), Schizophyllum commune, Tyromyces palustris, acetone extract, antifungal, manglid wood (Magnolia sumatrana (Miq.) Figlar & Noot), Schizophyllum commune, Tyromyces palustris

Judul: Anti-termite Properties of the Extractive Substance of Magnolia sumatrana (Miq.)) Against Subterranean Termites (Coptotermes curvignathus Holmgren).
Abstrak: Manglid (Magnolia sumatrana Miq.) merupakan salah satu jenis tanaman yang banyak dikembangkan di hutan rakyat Jawa Barat. Jenis ini relatif cepat tumbuh dan termasuk kelas awet II, sehingga memiliki ketahanan alami terhadap organisme perusak kayu. Penelitian ini bertujuan untuk mengetahui kadar ekstraktif kulit kayu manglid serta mengukur bioaktivitas zat ekstraktif tersebut terhadap rayap Coptotermes curvignathus Holmgren dan menganalisis komponen senyawa kimia yang terkandung di dalam fraksi teraktif. Ekstrak aseton yang diperoleh melalui ekstraksi dengan metode maserasi, difraksinasi secara bertingkat dengan pelarut n-heksan, etil eter, etil asetat. Analisis kimia dilakukan terhadap fraksi yang paling aktif dengan alat GC-MS. Fraksi etil asetat memiliki persentase mortalitas rayap rata - rata tertinggi sebesar 55,47 % serta persentase kehilangan berat kertas selulosa rata - rata terendah sebesar 24,89 %. Senyawa yang diduga mengandung bioaktivitas anti-rayap, yaitu (+)spathulenol dan (-)- Caryophyllene oxide., Manglid (Magnolia sumatrana Miq.) is a plant that is widely developed in the community forests of West Java. This species is relatively fast growing and has durable class II, so it has natural resistance to wood destroyers. This study aims to determine the extractive content of the manglid bark and to measure the bioactivity of the extractive substance against the termite Coptotermes curvignathus Holmgren and to analyze the components of chemical compounds contained in the most active fraction. The acetone extract obtained by extraction by maceration method was fractionated in stages with n-hexane, ethyl ether, and ethyl acetate as solvents. Chemical analysis was carried out on the most active fraction by means of GC-MS. The ethyl acetate fraction had the highest average termite mortality percentage of 55.47% and the lowest percentage of cellulose paper weight loss was 24.89%. The compounds suspected to contain anti-termite bioactivity are (+)spathulenol and (-)- Caryophyllene oxide.
Keyword: Ekstrak aseton, Kulit kayu manglid (Magnolia sumatrana Miq.), Rayap tanah (Coptotermes curvignathus), Bioaktivitas anti-rayap, Mortalitas, Kehilangan berat, Acetone extract, Manglid bark (Magnolia sumatrana Miq.), Subterranean termites (Coptotermes curvignathus), Anti-termites’ properties, Mortality, Weight loss

Judul: Dynamical System of Hepatitis B in Three Groups with Vaccination
Abstrak: The aim of this study is to modify the hepatitis B transmission model in three age groups involving vaccination from the model conducted by Zhoe and Zhang.The method used is to analyze the stability of the fixed point and its basic reproduction number (R_0). Performed stability analysis and numerical simulation to see population dynamics. Next, a sensitivity analysis of the parameters was carried out to see its effect on R_0. From the analysis obtained two fixed points, namely non-endemic and endemic fixed points. Non-endemic fixed points are locally asymptotically stable if R_0 <1 Meanwhile, the endemic fixed point is locally asymptotically stable if R_0 > 1. Hepatitis vaccination affects the number of susceptible population, because the more successful the vaccination, the smaller the number of susceptible populations so that the smaller the population will be infected.
Keyword: Dynamic, Hepatitis B, Vaccine, Mathematical model