Judul: Ecotourism Development Strategy in the Dampier Strait Marine Conservation Area Southwest Papua Province
Abstrak: The Dampier Strait regional conservation area is one of the conservation areas included in the Raja Ampat Regency marine conservation area, which has high potential for developing tourism activities. The most important aspect in the use of natural resources for tourism purposes is their suitability to support tourism activities. The challenge faced is the difficulty if the potential for beach tourism, snorkeling and diving to be developed simultaneously The aim of this research is to determine areas for ecotourism and recommend appropriate locations. Data analysis is determining ecotourism areas using the Technique For Order Preference by Similarity to Ideal Solution (TOPSIS). TOPSIS is used because it is able to rank the selected alternatives that are closest to the positive ideal and furthest from the negative ideal solution. The criteria used are tourist carrying capacity, accommodation, accessibility, number of international tourists, number of domestic tourists and suitability area. The results of this TOPSIS analysis are that Sauwandarek, Marandanweser and Arborek are areas that can be used as an alternative areas for carrying out beach tourism, snorkeling and diving activities. Areas that can be developed into ecotourism activities are Yeben Kecil and Tanjung Putus., The Dampier Strait Regional Marine Conservation Area (KKPD) is one of the conservation areas included in the Raja Ampat Regency Marine Conservation Area which has high potential for developing ecotourism activities. The most important aspect of the use of natural resources for ecotourism purposes is the suitability that supports ecotourism activities. The challenge faced is the difficulty if the potential for beach tourism, snorkeling and diving are to be developed simultaneously. Therefore, it is important to have an ecotourism development strategy in conservation areas. This research aims to evaluate the suitability and carrying capacity, determine alternative areas for ecotourism activities, and formulate ecotourism management strategies in the Dampier Strait. The research was carried out in September 2021 in several areas in the Dampier Strait, namely Yeben Besar, Yeben Kecil, Tanjung Putus, Arborek, Friwen, Sauwandarek, Waiweser, Yenbekwan, Marandanweser, Yef Adoak, and Dayan. Activities carried out include collecting data on the suitability of beach tourism, snorkeling, and diving, as well as direct observations to determine alternative tourism areas and ecotourism management strategies. The research results show that not all research areas can be used for beach, snorkeling and coastal tourism activities. Dayan is very suitable for beach tourism, snorkeling and diving, because the area has suitable values for the three ecotourism activities. However, it is also necessary to know the carrying capacity of each region, so that the visitor capacity does not exceed the carrying capacity of the region. Based on calculations of carrying capacity for beach activities, snorkeling and diving, it shows that many visitors can carry out tourist activities in the area. The largest beach carrying capacity is at Sauwandarek at 68,976 visitors/year, the largest snorkeling capacity is at Waiweser at 2,712 visitors/year, and the largest diving carrying capacity is at Dayan at 190 visitors/year. Alternative areas obtained through the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) analysis are Sauwandarek, Marandanweser, and Arborek. The main strategy that
Keyword: Ekowisata, konservasi, pesisir, Strategi

Judul: Sustainable Fisheries Development Strategy in the  Dampier Strait Tourism Park, Raja Ampat Regency
Abstrak: Potensi pemanfaatan kawasan pesisir dan laut untuk pengembangan aktivitas marikultur di Taman Wisata Perairan (TWP) Selat Dampier dapat dilihat dari ketersediaan ruang perairan dan keberadaan komoditas lokal. Akan tetapi, kondisi aktual kegiatan budidaya laut di TWP Selat Dampier belum ditopang oleh adanya basis perencanaan yang mampu mendukung pengelolaan kawasan secara berkelanjutan. Oleh karena itu, dibutuhkan langkah pengembangan yang komprehensif untuk mendorong implementasi akuakultur yang mengedepankan fungsi pelestarian alam dan integrasi ruang, merujuk dari status dan karakteristiknya sebagai Taman Wisata Perairan. Untuk mencapai hal tersebut, dilakukan beberapa tahapan analisis untuk menentukan daya dukung dan strategi pengelolaan melalui pendekatan marikultur yang berkelanjutan dengan konsep Ecosystem Approach to Aquaculture (EAA). Daya dukung fisik dinilai secara spasial menggunakan teknik Spatial Multi Criteria Evaluation. Daya dukung ekologi dan produksi diukur dengan pendekatan kapasitas fisik perairan. Daya dukung ekonomi dievaluasi melalui metode analisis biaya-manfaat (cost-benefit analysis). Strategi pengelolaan ditentukan lewat kajian deskriptif-kualitatif berdasarkan temuan yang diperoleh dari hasil pengamatan kondisi aktual karakteristik usaha budidaya laut dan penilaian daya dukung. Luas potensial perairan yang dapat dimanfaatkan untuk pengembangan aktivitas marikultur adalah 886,38 ha (0,38% dari total alokasi ruang sebesar 232.588,59 ha). Jumlah unit budidaya rumput laut dan tiram mutiara yang dapat dikembangkan sebanyak 704 dan 805 unit dengan volume produksi per tahun rumput laut kering dan spat tiram mutiara siap operasi sekitar 4.660,46 ton dan 2.817.753 individu. Berdasarkan hasil analisis biaya-manfaat, usaha budidaya laut kedua komoditas laik untuk dikembangkan dengan telah memenuhi persyaratan kelayakan bisnis berdasarkan perbandingan nilai biaya dan manfaat, tingkat persentase keuntungan, taraf pengembalian aset, selisih dan perbandingan antara pengeluaran dengan penerimaan, serta waktu pemulangan modal. Strategi pengelolaan yang direkomendasikan meliputi pemantauan secara berkala terhadap usaha marikultur, kondisi lingkungan perairan dan kualitas air, kesesuaian lahan, daya dukung kawasan, skema peningkatan kapasitas sumberdaya manusia, serta sistem tata kelola ruang yang mencakup pengaturan desain tata letak konstruksi budidaya dan mekanisme pengendalian pemanfaatan ruang. Seluruh tahapan analisis telah mampu menampilkan hasil yang komprehensif untuk mencapai pemanfaatan kawasan secara optimal dan berkelanjutan dari adanya pengembangan aktivitas marikultur. Hal tersebut telah mempertimbangkan kesinambungan antara potensi lingkungan dengan adanya tuntutan manusia dalam memanfaatkan jasa ekosistem secara terpadu. Hasil analisis data direkomendasikan sebagai mekanisme arahan pemanfaatan ruang dan pedoman pengelolaan kawasan.
Keyword: suitability, carrying capacity, seaweed, pearl oyster, Ecosystem  Approach to Aquaculture (EAA)

Judul: Mathematical model of Hematopoietic Stem Cell in Chronic Myelogenous Leukemia with and without Therapy
Abstrak: Leukemia or blood cancer is a diverse group of neoplastic disease, characterized by the multiplication of abnormal leukocytes or malignant transformation of blood-forming cells in bone marrow and lymphoid tissues. One of the most common types of leukemia is Chronic Myelogenous Leukemia (CML), which is usually diagnosed by the presence of certain chromosomal abnormalities, the so-called Philadelphia chromosome (Ph). One of the treatments of CML is Granulocyte Colony-Stimulating Factor (G-CSF). In this paper, we discuss two Hematopoietic Stem Cell (HSC) models, i.e. HSC without treatment and HSC with G-CSF treatment. The model of HSC without treatment included three equations representing the dynamics of HSC, leukocyte and platelet. Whereas, the model of HSC with G-CSF treatment includes the previous three equations and adds two more equations representing G-CSF injection and G-CSF circulation. The stability behavior of the system approaching the equilibrium points in the simulation study is carried out using Mathematica 7.0. The simulation results show that the G-CSF treatment can successfully decrease the number of HSC, which means reducing the CML.
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