Judul: Literature Study of Traditional Use, Biological Activity, and Phytochemical Profile of Keji Beling (Strobilanthes crispus)
Abstrak: Masyarakat Indonesia banyak memilih pengobatan tradisonal dibandingkan pengobatan secara modern pada beberapa tahun terakhir. Hal ini karena efek samping obat-obatan modern cukup berbahaya dan harganya relatif mahal. Salah satu tanaman yang berpotensi sebagai obat herbal ialah keji beling (Strobilanthes crispus). Penelitian ini bertujuan mengumpulkan informasi terkait penggunaan tradisional, aktivitas biologis serta profil fitokimia, dan senyawa aktif ekstrak daun spesies tersebut berdasarkan telaah pustaka. Hasilnya menunjukkan ekstrak daun digunakan sebagai obat herbal, dikonsumsi dengan cara direbus atau diseduh sebagai teh kemudian diminum. Aktivitas biologisinya ialah antioksidan, antidiabetes, antikanker, antitumor, dan antibakteri. Golongan senyawa kimia yang terdapat dalam ekstraknya ialah flavonoid, alkaloid, saponin, tanin, dan terpenoid. Senyawa kimia yang dilaporkan memiliki aktivitas biologis antara lain asam silikat, polifenol, dan glikosida, serta dari golongan flavonoid seperti katekin, rutin, epikatekin, mirsetin, luteolin, apigenin, naringenin, dan kaempferol., Many Indonesian people have chosen traditional medicine over modern medicine in recent years. This is because the side effects of modern medicines are quite dangerous and the price is relatively expensive. One of the plants that have the potential as herbal medicine is keji beling (Strobilanthes crispus). This study aims to collect information related to traditional uses, biological activities as well as phytochemical profiles and active compounds of leaf extracts of these species based on a literature review. The results show that the leaf extract is used as herbal medicine, consumed by boiling or brewed as tea and then drink. Its biological activities are antioxidant, antidiabetic, anticancer, antitumor, and antibacterial. The chemical compounds contained in the extract are flavonoids, alkaloids, saponins, tannins, and terpenoids. Chemical compounds reported having biological activity include silicic acid, polyphenols, and glycosides, as well as from the flavonoid group such as catechins, rutin, epicatechin, myrcetin, luteolin, apigenin, naringenin, and kaempferol.
Keyword: aktivitas biologis, fitokimia, Strobilanthes crispus

Judul: The Effectiveness of Keji Beling (Strobilanthes crispus Blume)  Leaf Infusion as Antidiarrheal in Mice (Mus musculus)
Abstrak: Tanaman keji beling telah lama digunakan untuk pengobatan penyakit pada manusia, namun penelitian terkait manfaat tanaman keji beling sebagai antidiare masih sedikit. Tujuan penelitian ini adalah mengevaluasi secara ilmiah efek infusa daun keji beling sebagai antidiare dengan metode proteksi intestinal dan transit intestinal pada mencit. Penelitian ini menggunakan 36 ekor mencit yang dibagi menjadi enam kelompok terdiri dari kelompok kontrol negatif (Tween 80 [1%]), kontrol positif (suspensi loperamid HCl), dan empat kelompok perlakuan infusa daun keji beling dengan konsentrasi 12,5%, 25%, 50%, dan 100% yang diberikan secara oral. Parameter yang diamati yaitu frekuensi defekasi, konsistensi feses, dan rasio lintasan marker usus. Berdasarkan metode proteksi intestinal, infusa daun keji beling dengan konsentrasi 12,5%, 25%, dan 50% memiliki efek antidiare, sedangkan pada metode transit intestinal hanya infusa daun keji beling konsentrasi 50% yang memiliki efek antidiare. Berdasarkan kedua metode, infusa daun keji beling konsentrasi 50% menunjukkan efek antidiare yang paling efektif., Keji beling plant has long been used for the treatment of diseases in human, but research regarding the benefits of the keji beling plant as an antidiarrheal are still few. The purpose of this study was to evaluate scientifically the effect of keji beling leaf infusion as an antidiarrheal with intestinal protection and intestinal transit method in mice. This study used 36 mice which were divided into six groups consisting of a negative control group (Tween 80 [1%]), a positive control group (loperamide HCl suspension), and four groups of treatment with a keji beling leaf infusion concentration of 12,5%, 25%, 50%, and 100% given orally. The parameters observed were the frequency of defecation, the consistency of faeces, and the ratio of marker passages in the intestines of mice. Based on intestinal protection method, infusion of keji beling leaf with concentrations of 12.5%, 25%, and 50% has an antidiarrheal effect, while in the intestinal transit method only the infusion of keji beling leaf with concentration of 50% has an antidiarrheal effect. Based on the two methods, infusion of keji beling leaf at a concentration of 50% showed the most effective antidiarrheal effect.
Keyword: antidiarrhea, intestinal protection, intestinal transit, Strobilanthes crispus

Judul: Approximation of the Median of Poisson Distribution Using the Relation of Poisson-Gamma Distribution
Abstrak: A major drawback of median is that median cannot usually be defined in closed form, even in the cases where their distribution functions are known. This study gives an approximation of the closed form for the median of the Poisson distribution by using the relation of Poisson-Gamma distribution. The approximation uses elementary techniques based on the monotonicity of certain sequences involving tail probabilities of the Poisson distribution and the Central Limit Theorem. Furthermore, a closed form expression for the mean absolute deviation 􀜧|􀜰􀰒 􀵆 􀜯􀝁􀝀􁈺􀜰􀰒􁈻| is also studied. The median is relevant because of the fact that it minimizes the mean absolute deviation of a Poisson random variable (􀜰􀰒􁈻 by considering median as central tendency.
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