Judul: Trend desain penanaman pada lanskap permukiman Bogor Nirwana Residence
Abstrak: Bogor Nirwana Residence (BNR) is a housing estate in Bogor city which has nature concept. Each area in BNR has different planting design trends which are interesting to be studied. The objectives of this study were to identify plants diversity and elements of planting design, to analyze planting design trends and to propose a recommendation of planting design concept for residential landscape of BNR. Method used in this study was survey method with descriptive analysis, which consisted of site inventory, analysis and synthesis stage (arranging recommendation). This study focused on plants dominants, species diversity, functional and aesthetic aspects of the plant arrangements. Results of the study showed that there were 128 species of plants in the whole area of study. The diversity varied from 0,07 to 1,1. Plant types which had highest dominant scores were trees on the main road and groundcovers on cluster gates, public parks and fronthouse gardens. Functional aspects scores on main road classified into poor with score 58,6%, while public park classified into fair with score 63,8%. Aesthetic aspects scores on whole area of study classified into fair, varied from 64,4% to 75,6%. Recommendation of planting design concept was made following ideal criteria of required functional aspects on each area of study.
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Judul: Penilaian Aspek Fungsi dan Estetika Tata Hijau Jalan Utama Kawasan Permukiman Bogor Nirwana Residence.
Abstrak: Bogor Nirwana Residence (BNR) merupakan salah satu permukiman besar di Kota Bogor yang menerapkan konsep Inspired by Nature, yakni dengan mengalokasikan 60% dari lahannya sebagai ruang terbuka hijau. Jalan utama pada kawasan permukiman ini merupakan salah satu ruang terbuka hijau yang memiliki fungsi untuk memperbaiki kualitas lingkungan, dan fungsi estetis untuk memperindah lingkungan. Mengingat tingginya tingkat pergerakan atau mobilitas penduduk dan pengunjung pada jalan utama BNR, maka perlu diketahui kesesuaian pemilihan jenis dan penataan komposisi tanaman pada konsep tata hijau jalan utama kawasan permukiman BNR dengan mengkaji fungsi dan estetika. Penilaian dilakukan dengan membandingkan kondisi tanaman yang ada di lapang dengan kriteria standar yang didapatkan dari studi pustaka. Tujuan dari penelitian ini adalah untuk mengidentifikasi dominansi dan keragaman elemen tanaman, dan menganalisis nilai fungsi dan estetika tata hijau jalan utama kawasan permukiman BNR, serta menyusun rekomendasi dalam usaha peningkatan nilai fungsional dan estetika tata hijau jalan utama kawasan permukiman BNR. Penelitian ini menggunakan metode survei dan analisis deskriptif. Aspek yang diamati meliputi fungsi pembatas visual (screen), kontrol kesilauan (median), peneduh, penahan erosi, dan pengarah, serta fungsi estetika meliputi pemilihan jenis tanaman dan pengaturan tanaman. Dari hasil pengumpulan data, terdapat 84 spesies tanaman dengan nilai dominansi tertinggi merupakan tanaman jenis pohon dan tingkat keragaman tanaman rendah. Berdasarkan penilaian aspek fungsi pada 11 segmen jalan utama, 5 segmen termasuk kategori sangat baik, 5 segmen dikategorikan baik, dan 1 segmen dikategorikan buruk. Penilaian aspek estetika menunjukkan bahwa 6 segmen termasuk kategori sangat baik, dan 5 segmen termasuk kategori baik. Pada segmen yang telah memenuhi kriteria aspek fungsi dan estetika dengan kategori sangat baik perlu dipertahankan serta menjadi contoh bagi segmen lainnya, sedangkan pada segmen yang belum baik diperlukan peningkatan untuk memenuhi kriteria tersebut.
Keyword: Aspek fungsi, estetika, jalan utama, tata hijau

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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