Judul: Klasifikasi landform menggunakan metode desaunettes dan hubungannya dengan pola penggunaan lahan suatu studi kasus daerah Bandung Selatan
Abstrak: Suatu hal penting dalam upaya perencanaan dan pengem- bangan lahan, terutama untuk tujuan usaha pertanian adalah diperlukannya data dan informasi mengenai keadaan lahan se- cara lengkap. Tujuan penelitian ini adalah mengkelaskan, memetakan dan menganalisis lahan sebagai upaya penyediaan informasi dasar tentang fisik lahan, serta membandingkan kondisi peng- gunaan lahan dan kesesuaiannya pada tiap-tiap landform. Dalam memetakan landform digunakan konsep Desaunettes (1977) dalam Catalogue of Landform for Indonesia sebagai acuan, sedangkan pengkelasan penggunaan lahan berdasarkan Maling- reau (1981). Penelitian ini dilaksanakan di daeran Bandung Selatan.
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Judul: Survei dan Pemetaan Bentuk Lahan Semidetil di Kecamatan Darmaga dan Sekitarnya, Kabupaten Bogor, Jawa Barat
Abstrak: Bentuk lahan mempunyai arti penting dalam Ilmu Tanah karena bentuk lahan mempunyai hubungan yang sangat erat dengan sifat-sifat tanah. Menurut van Wambeke (1986) bentuk lahan memiliki hubungan dengan tanah dalam hal faktor-faktor pembentuknya sehingga satuan lahan merupakan wadah satuan tanah. Dalam perencanaan tataguna lahan diperlukan informasi mengenai bentuk lahan karena bentuk lahan dapat membantu dalam menentukan tipe penggunaan lahan dan perkembangan dari infra struktur. Bentuk lahanjuga memberi kerangka keIja yang berguna dalam survei tanah dan evaluasi lahan.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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