Judul: Peramalan Penjualan dan Keuntungan Kotor Produk Olahan Lebah Madu
Abstrak: Adanya fluktuasi penjualan menyebabkan perusahaan sulit dalam mengambil kebijakan mengenai perencanaan penjualan dan perolehan keuntuugan kotor. Fluktuasi penjualan tersebut dikarenakan beberapa hal, diantaranya adalah adanya perubahan konsumsi produk olahan lebah menjelang hari raya keagamaan, rendahnya produksi lebah madu tiap kali panen dan kurangnya promosi yang dilakukan perusahaan.
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Judul: Analisis Profitabilitas Perusahaan dan Peramalan Penjualan Produk Lebah Madu (Studi Kasus pada Unit Usaha Apiari Pramuka di Cibubur-Jakarta)
Abstrak: Indonesia memiliki potensi sumberdaya yang besar untuk pengembangan lebah madu, sehingga penelitian tentang berbagai produk perlebahan sangat menarik dan perlu dilakukan. Walaupun deinikiali pemasaran berbagai produk perlebahan di Indonesia masih menghadapi beberapa kendala antara lain: persepsi ~nasyarakat yang menganggap rnadu sebagai obat sehingga konsu~nsim adu sangat terbatas, pendapatan perkapita sebagian besar ~nasyarakat masih rendah, lnutu madu yang bervariasi dan adanpa saingan dari madu impor. Kondisi ini merupakan tantangan bagi unit-unit usaha yang bergerak di bidang perlebahan terutama untuk pengembangan pemasarannya.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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