Judul: Determining Optimal Distribution Route on the Supply Chain Network using Genetic Algorithm.
Abstrak: In the past few years, the Supply Chain Network (SCN) field has gained more attention due to the competition which is introduced by the market globalization. Distribution network design is one of the most comprehensive and strategic decision problem that need to be optimized for efficient operation on the supply chain field. The distribution network design establishes distribution channels, determines the amount of materials and items to consume, and also ships the product from suppliers to customers. The optimal distribution depends on the optimal route, which is influenced by the distance and the distribution time. This paper presents a genetic algorithm approach to determine optimal distribution route. Genetic algorithm was implemented to search the optimal route from the start point to the destination point. Priority-based chromosomes (strings) and their genes (parameters) were used to encode the problem. Weight Mapping Crossover and Swap Mutation were used as genetic operator, while the selection method used was roulette wheel. The algorithm was tested in a road map containing 44 nodes and from the experiments, we could conclude that the genetic algorithm system design worked well to solve the optimation problem. Keywords: Supply Chain Network, Genetic Algorithm, distribution route.
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Judul: Penyelesaian Vehicle Routing Problem pada Pendistribusian Sayuran Dataran Tinggi Menggunakan Algoritme Genetika (Studi Kasus PT Saung Mirwan)
Abstrak: Vehicle routing problem (VRP) is an important issue on a transportation system that aims at minimizing the total vehicle mileage to reduce vehicle operating cost to a minimum. Vehicle routing problem belongs to the class of non-polynomial hard (NP-hard), which generally uses a heuristic approach to find a solution. In this time, Vehicle routing problem resolution will be applied to the distribution of highland vegetables from PT. Saung Mirwan as the vegetable distribution center. The problems that often arise in the distribution of highland plain vegetables is to how minimize the total of transportation costs without sacrificing the goal completion time to reduce the risk of the decline in the quality of vegetables during the trip. Issues will become increasingly complex if the vehicle routing problem is flexible to changes that occur in the limit or the value of decision variables. The problems encountered in this case include heterogeneous multi fleet VRP, single source, single trip, and multi-product. Therefore, this research used genetic algorithm optimization method (GA) to solve the problem. Genetic algorithm is one of the heuristic methods, which is analogous to the process of evolution by natural selection phase, crossover and mutation. In this paper a simulation is performed by searching the optimum solution to the location of the distribution as the destination points. Optimum solutions are obtained in the form of division of highland vegetable distribution channels that meet the existing constraints. As a solution, there was reduction of the distribution time of about 1 hour 58 minutes or an increase in time efficiency by approximately 32.22% and a reduction of the fleet utilization by 1 fleet or an increase of fleet efficiency by 14.28%.
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Judul: Penapisan Hepadnavirus Secara Serologik Dan Molekuler Pada Monyet Ekor Panjang (Macaca Fascicularis) Di Habitat Ex-Situ
Abstrak: Penemuan infeksi virus hepatitis B (VHB) monyet ekor panjang (Macaca fascicularis) di Pulau Mauritius pada tahun 2013 merupakan temuan baru yang menunjukan bahwa penyakit ini dapat menginfeksi jenis satwa primata dari famili Cercopithecidae. Temuan tersebut hanya dilaporkan pada M. fascicularis yang berada di benua Afrika, sehingga menjadi alasan dilakukannya investigasi pada M. fascicularis asal Indonesia. Untuk mendapatkan gambaran keadaan tersebut, sampel darah M. fascicularis diambil dari berbagai lokasi habitat ex-situ. Uji penapisan terhadap antigen permukaan virus hepatitis B (Hepatitis B surface antigen, HBsAg) dilakukan pada 95 sampel plasma dan serum M. fascicularis yang berasal dari penangkaran, pusat penyelamatan satwa, dan topeng monyet. Upaya pemeriksaan DNA VHB dilakukan pada sampel yang menunjukan hasil seropositif terhadap HBsAg. Uji penapisan menunjukan bahwa sebanyak 11 dari 95 (11.6%) sampel reaktif terhadap HBsAg. Antigen permukaan virus hepatitis B lebih banyak ditemukan pada monyet di pusat penyelamatan satwa dan topeng monyet (55%) dibandingkan dengan satwa penangkaran (45%). Hasil seropositif HBsAg pada sampel M. fascicularis yang diperiksa dengan teknik ELISA menggunakan kit HBsAg manusia mengindikasikan adanya kemiripan protein antigen permukaan VHB manusia dengan yang ditemukan pada M. fascicularis, karena antibodi monoklonal yang digunakan dalam uji ELISA pada penelitian ini bersifat spesifik mengikat HBsAg manusia. Meskipun uji PCR terhadap sampel tersebut tidak menunjukkan adanya DNA VHB, hasil seropositif HBsAg mengindikasikan bahwa M. fascicularis dapat terinfeksi VHB atau virus yang mirip VHB secara alami.
Keyword: virus hepatitis B, monyet ekor panjang, habitat ex-situ