Judul: Uji Sitotoksisitas dan AktivitasEkstrak Daun Leunca (Solanum nigrum L) Terhadap Kelarutan Kalsium Oksalat
Abstrak: Various studies have shown that Leunca plants especially the fruit and leaves have many pharmacological activities. This study aims to examine the bioactive components of Leunca leaf qualitatively, cytotoxicity and activity of Leunca leaf extracts through the solubility of calcium oxalate that main ingredient constituent of kidney stones. Extraction Leunca leaf maceration is done using a variety of solvents, namely water, 30% ethanol, 70% ethanol and 96% ethanol. Based on the extraction solvent extract obtained by extraction of water, 30% ethanol, 70% ethanol and 96% ethanol at 39.67, 19.00, 17.66 and 26.63%. Phytochemical components contained in Leunca leaves are alkaloids, flavonoids, tannins and saponins. The results of measurements of calcium levels using turbidimetri and AAS methods showed decreased levels of calcium. Best decline is there in the addition of solvent water extract at a concentration of 1.5%. The test results indicate that the biological potential of the best extract owned by the water extract with LC50 values of 136.435 ppm.
Keyword: Bogor Agricultural University (IPB)

Judul: Aktivitas Antikalkuli Ekstrak Etanol Tapak Dara (Catharanthus roseus) Secara In Vitro dan In Vivo pada Tikus dengan Induksi Etilen Glikol
Abstrak: Catharanthus roseus leaf is empirically utilized plant to treat the kidney stone. Otherwise, this thing hasn’t been proved scientifically. The aim of this research is to test the 96% ethanolic extract of leaf in vitro at calcium oxalate crystal and in vivo at Sprague dawley rat which induced with ethylene glycol 0.75%. The phytochemical screening and decay of calcium oxalate was performed during in vitro assay than the creatinine and calcium oxalate in vivo content was measured. The water content value of symplisia as 3.83% and extract rendement as 32.129%. The analysis result of phytochemical extract contains flavonoid, alkaloid, saponin, tanin and triterpenoid. The in vitro anticalculi activity showed ability of calcium oxalate crystal aggregation inhibition. The in vivo anticalculi activity indicates recovery of renal function and reduce amount of deposited kidney crystal. The extract with dose 100 mg/kg body weight and 300 mg/kg body weight wasn’t significally different at (p<0.05). Catharanthus roseus ethanolic extract potentially treat the kidney stone in vitro and in vivo
Keyword: Bogor Agricultural University (IPB), Anticalculi., Sprague dawley, Catharanthus roseus

Judul: Infeksi Virus Parainfluenza Pada Anjing
Abstrak: Virus parainfluenza anjing termasuk famili Paramyxoviridae, berbentuk pleomorf dengan ukuran bervariasi (bergaris tengah antara 100-500 nm), berpembungkus peka ether, berisi genom RNA dan secara serologis mempunyai kesamaan dengan virus SV-5 kera; dikenak sebagai salah satu kausa penting dari sindrom "kennel cough". Infeksinya dapat mengenai anjing semua umur yang belum pernah terinfeksi atau mendapatkan vaksinasi mengakibatkan gejala klinis ringan yang terbatas pada traktus respirasi atu infeksi yang secara klinis tidak memperlihatkan gejala nyata. Gejala klinis yang nampak setelah masa inkubasi (1-5 hari) terlewati berupa batuk yang tidak berat selama beberapa hari, berbagai tingkat tonsilitis dan pharyngitis dan kadang-kadang ditemukan kenaikan temperatur rektal antara 1-2 derajat C dari temperatur normal rat-rata. Anjing terinfeksi mengandung virus pada traktus respirasi bagian atas dan bawah serta limfonoduli sampai hari ke 9 setelah infeksi. Penyebaran virus antar anjing terjadi secara aerogen.
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