Judul: Model’s Dynamics for Lymphocytes Recovery on the HIV presence with Protease Inhibitor Therapy.
Abstrak: HIV is a member of retrovirus that especially attacks lymphocytes or white blood cells, known as CD4+ T cells. New T cells created from sources within the body such as the thymus and by proliferation of existing T cells. In this paper, influence of protease inhibitor therapy in HIV dynamics will be analyzed. The influence can be categoried in three models, which are model HIV without drug therapy, model HIV with protease inhibitor and model T cell recovery. In the models, three parameters which are uninfected cells population, infected cells population and virus population are studied. From HIV without drug therapy model it is obtained two types fixed point which are uninfected fixed point and infected fixed point. The stability of fixed point depends on basic reproduction number which is influenceed by the total number of virus produced by a cell during its lifetime. From HIV with protease inhibitor therapy model it is obtained two type fixed points. The stability of fixed point depends on basic reproduction number. Other than influenceed by the total number of virus produced by a cell during its lifetime, basic reproduction number of this model also affected by the effectiveness of a protease inhibitor. Basic reproduction number of this model is smaller than that of model HIV without drug therapy. In the model T cell recovery, new T cells created only from sources within the body, and T cells can be invulnerable to HIV infection after the therapy. From the model it is obtained only one fixed point that is uninfected fixed point. The stability of fixed point depends on basic reproduction number. The total number of virus produced by a cell during its lifetime and the effectiveness of a protease inhibitor determine the basic reproduction number. Basic reproduction number of this model is smallest than that of other models.
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Judul: The Dynamic of HIV Virus Infection as a Result of Protease Inhibitor Therapy.
Abstrak: Acquired immunodeficiency syndrome (AIDS) is defined as symptoms of deterioration human immune system caused by human immunodeficiency virus (HIV). The virus damages the leucocytes; therefore, once a person infected by the HIV, his/her immune system will be paralyzed and eventually will not be able to survive from any disease. HIV is transmitted in many ways, such as having unsafe sex, using unsterilized syringe, blood transfusion, and many more. So far, there has not been discovered yet a way or a medicine that can totally cure this disease. However, reverse transcriptase inhibitor therapy, protease inhibitor, or combination of those two can decline the growth of virus inside the body of the infected person. Therefore, the immune system will be enhanced back to normal phase. In this paper, will analyze the effect of protease inhibitor therapy on the dynamics of virus inside the blood with different value of effectiveness. There are two mathematical models of protease inhibitor therapy to consider, i.e. perfect and imperfect protease inhibitor. The perfect protease inhibitor therapy hinders the virus to grow well and not to infect healthy leucocytes. On the other hand, the imperfect one cannot completely detained the virus growth.
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Judul: Metil Ester Gondorukem sebagai Kandidat Bahan Bakar Nabati
Abstrak: The objective of this research is to produce ester of rosin distillate using methanol and H2SO4 (pa) as a catalyst. The result showed an optimum yield of methyl ester was 88.5% at an operating condition of 1.2 mL catalyst in 1.5 hours. The infrared spectra showed that carboxyl groups was replaced by C=O ester group, proofing that the rosin distillate was esterified. Furthermore, the gas chromatography-mass spectrometer spectra showed that the resin acids consists of ester derivates of abietic acid, sandaracopimaric acid, dehidroabietic acid, isopimaric acid, palustric acid. Based on SNI 04 -7182-2006, the kinematic viscosity at 40ºC (4.2 mm2/s), cloud point (-18ºC), total sulfur (67 ppm), acid number (0.1 mg-KOH/g), iodine number (12.8%), and total alkyl ester (99.8%), the methyl ester of pine rosin would be feasible to be used as a biodiesel material. The flash point was considered too low for biodiesel, but would be suitable f or biogasoline.
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