Judul: The Erythrocyte Profiles in Pregnant Friesian Holstein Cows after Administered Avian Influenza H5N1 Vaccine
Abstrak: Penelitian ini bertujuan untuk mempelajari profil parameter eritrosit pada induk sapi bunting yang divaksin dengan vaksin AI H5N1. Sebanyak sembilan ekor induk sapi FH bunting trimester akhir, sehat secara klinis digunakan dalam penelitian ini. Induk sapi dibagi ke dalam tiga kelompok (n-3 ekor), yaitu kelompok control (tidak diberi imunomodulator, antigen AI H5N1, dan vaksin AI H5N1 inaktif), kelompok perlakuan 1 (tidak diberi imunomodulator, diberi antigen AI H5N1, dan vaksin AI H5N1 inaktif), dan kelompok perlakuan 2 (diberi imudomodulator, antigen AI H5N1, dan vaksin AI H5N1 inaktif). Imunomodulator (ribonucleotide polypeptide) diberikan secara oral dengan dosis 0,1 mg/kgBB tiga hari berturut-turut. Antigen H5N1 diberikan secara intravena selama tiga hari berturut-turut dengan dosis 104 HAU/ekor. Vaksin AI H5N1 inaktif plus adjuvant diberikan dua kali, masing-masing sebanyak 5 dosis/ekor secara subkutan, dengan interval waktu antar vaksinasi selama dua minggu. Pengambilan sampel darah dilakukan melalui vena coccygea pada saat sebelum vaksinasi pertama, 2 minggu setelah vaksinasi pertama, 2 minggu setelah vaksinasi kedua, satu minggu setelah vaksinasi ketiga, dan 2 minggu setelah vaksinasi ketiga untuk dianalisis terhadap jumlah eritrosit, nilai hematokrit, kadar hemoglobin, dan indeks eritrosit. Hasil pengamatan menujukkan bahwa tidak ada perbedaan nyata pada jumlah eritrosit, nilai hematokrit, kadar hemoglobin, nilai MCV, MCH, dan MCHC pada induk sapi bunting setelah vaksinasi, baik antar perlakuan maupun antar waktu pengamatan (P>0,05). Vaksinasi menggunakan vaksin Avian Influenza H5N1 inaktif pada induk sapi Friesian Holstein bunting trimester akhir tidak berpengaruh pada nilai parameter eritrosit., The objective of this experiment was to study the erythrocytes profile in pregnant Friesian Holstein (FH) cows after administered by Avian Influenza H5N1 vaccine. This experiment used nine pregnant FH cows in the last trimester of pregnancy. The cows were divided into three groups that consist of three cows for each group which are the control group (no imunomodulator, no AI H5N1 antigen, and no AI H5NI vaccine), group A (no immunomodulator, but administered with AI H5N1 antigen and AI H5N1 vaccine), and group B (administered with immunomodulator, AI H5N1 antigen, and AI H5N1 vaccine). Immunomodulator (ribonucleotide polypeptide) was administered orally with 0.1 mg/body weight dose. Antigen of inactive H5N1 was given by intravenous administration for consecutively in three times with 104 HAU/each cow. Avian influenza H5N1 inactive commercial vaccine was subcutaneously administered twice, with 5 doses/each cow in 2 weeks of the time interval between vaccination. The blood collection were taken from coccygeal vein before the first vaccination, two weeks after the first vaccination, two weeks after the second vaccination, one week and two weeks after the third vaccination to be analyzed for the number of erythrocytes, haematocrit, haemoglobin, Mean Corpuscular Volume, Mean Corpuscular Haemoglobin, and Mean Corpuscular Haemoglobin Concentration. The result showed that the pregnant cow’s erythrocyte parameter were not significantly different between treatments and also between the time of examination (P>0.05). In conclusion, the administration of Avian influenza H5N1 vaccine to the last trimester of pregnancy Friesian Holstein cows didn’t affect the erythrocyte parameter profiles.
Keyword: Flu Burung, Sapi Bunting, Vaksin AI H5N1, Parameter Eritrosit

Judul: Profil Fraksi Protein Induk Sapi Friesian Holstein Bunting Trimester Akhir yang Diberi Vaksin Flu Burung H5N1
Abstrak: Penelitian ini bertujuan untuk mempelajari pengaruh vaksinasi pada induk sapi bunting yang divaksin dengan vaksin inaktif flu burung H5N1terhadap profil fraksi protein. Sebanyak 10 ekor induk sapi FH bunting trimester akhir, sehat secara klinis, dibagi menjadi 2 kelompok, yaitu 3 ekor induk sapi kelompok kontrol dan 7 ekor induk sapi kelompok vaksin. Vaksinasi induk sapi dilakukan secara subkutan sebanyak 3 kali dengan jarak antar vaksinasi 2 minggu. Sampel darah diambil melalui vena coccygea, dimulai pada saat sebelum vaksinasi pertama, dan selanjutnya setiap 2 minggu sampai induk sapi melahirkan untuk dianalisis terhadap konsentrasi total protein, albumin, globulin dan rasio albumin terhadap globulin (rasio A/G). Analisis fraksi protein menggunakan metode fotometer. Hasil penelitian menunjukkan tidak ada perbedaan pada konsentrasi total protein, albumin, globulin dan rasio A/G antar kelompok dan antar waktu vaksinasi (P>0.05). Dapat disimpulkan bahwa vaksinasi pada induk sapi bunting trimester akhir menggunakan vaksin inaktif flu burung H5N1 tidak memengaruhi profil fraksi protein.
Keyword: Albumin, globulin, total protein, vaksin flu burung H5N1

Judul: Penyusunan Overlap Graph menggunakan Suffix Tree pada DNA Sequence
Abstrak: The DNA sequence assembly is very important in genome analysis. This step aims to reconstruct contigous DNA fragment (contigs) from short fragment by concatenating fragments based on the overlap region among them. This method employs overlap graph for solving the problems. In this graph, nodes represent fragments and edges represent overlap. This research developed a software for constructing overlap graph using suffix tree. The evaluation was conducted by measuring the number of nodes, number of edges, and the execution time in many values of minimum overlap. The minimum overlap is defined as the minimum length of substring which is considered as the overlap region between two fragments. The evaluation results showed that the number of nodes, the number of edges, and the execution time were increased with the decreasing of the minimum overlap value.
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