Judul: Pertumbuhan Fisik dan Somatotype Anak Sekolah Suku Sasak pada Ketinggian Berbeda di Pulau Lombok
Abstrak: The human life cycle can be staged into neonatal, infancy, childhood, juvenile, puberty, adolescence, adulthood, and senescence. During this cycle, the body changes significantly in size, structure, proportions, and composition. The physical growth and somatotype of schoolchildren are one of the important phases in human life cycle. The puberty stage within this age range are indicated by the growth spurt of stature (BH) and weight (BW) and followed by change in somatotype. The focus of this research is to evaluate the age-related body size and shape variations at different altitude in Sasak children. A cross sectional growth study was conducted during July to December 2012. The samples are students of kindergarten to senior high schools aged 3 to 19 years. All of subjects are rural children who lives in low (16 to 28 m asl), medium (525 to 628 m asl), and high altitude (1130 to 1213 m asl). Ten anthropometric measurements are used to determined the growth of body size and shape. The result showed the children in low altitude were higher and heavier than medium and high altitudes. Until puberty, the children in medium have same stature and weight with those reside in high altitude but shorter and lighter thereafter. The difference of height and weight are statistically different in girls and indifferent in boys. In growth of body shape, the Sasak children have a common pattern of somatotype composition. It is an increased in endomorphy, a decreased in mesomorphy, and an increased in ectomorphy during growth. The girl in medium altitude show delayed and slowly increasing of endomorphy and slowly decreasing of mesomorphy. Socioeconomic factors such as family income and parental education gave more influence to the differentiation than the altitude factor.
Keyword: Altitude, Growth, Sasak, Somatotype

Judul: Somatotypes of Bekasi Children and Adolescent Aged 3-20 Years
Abstrak: Salah satu metode kuantitatif untuk mendeskripsikan bentuk dan komposisi tubuh adalah somatotipe. Somatotipe dinyatakan dalam tiga urutan angka yang masing-masing mewakili endomorf, mesomorf, dan ektomorf. Indonesia memiliki suku, sosiokultur, dan latar belakang sosio-ekonomi yang beragam sehingga penting untuk mempelajari variasi bentuk dan komposisi tubuh menggunakan metode kuantitatif di setiap kotanya. Tujuan penelitian ini adalah menjelaskan somatotipe anak dan remaja usia 3-20 tahun di Bekasi. Pengukuran somatotipe menggunakan metode yang diperkenalkan Carter dan Heath. Komponen somatotipe berubah seiring pertambahan usia. Pada usia 3 tahun perempuan memiliki somatotipe mesomorf-endomorf. Somatotipe berubah dari endomorf menjadi mesomorf dan ektomorf yang seimbang setelah usia 12 tahun. Somatotipe laki-laki pada usia 3 tahun adalah mesomorf-ektomorf. Somatotipe lalu berubah menjadi endomorf berimbang pada usia 13 tahun. Pada usia 20 tahun, somatotipenya tetap endomorf berimbang. Secara umum, komponen endomorf perempuan naik sedangkan laki-laki turun. Komponen mesomorf dan ektomorf laki-laki lebih tinggi daripada perempuan di setiap tingkat usia.
Keyword: anak dan remaja, Bekasi, somatotipe

Judul: Isolasi dan pemurnian bahan aktif dari mikroalga BTM 11 sebagai inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus is the cause of hepatitis C disease which has high virulence. Recent therapy using combination of ribavirin and alpha interferon has short efficiency < 80%. Thus, the discovery of new drug is needed. Antiviral drugs can be discovered through molecular target therapy by finding the inhibitor of RNA helicase that play role in viral replication. Inhibitor can be derived from chemical compound produced by microalgae. The aim of this research was to isolate the active compound from microalgae BTM 11 which had inhibitory activity against RNA helicase. Inhibitory activity was measured by releasing of phospate inorganic in colorimetric ATPase assay. Crude extract was fractionated using gel filtration chromatography with methanol in chloroform solvent. The result showed that Fraction 3 has the highest inhibitory activity which (81.205%). Phytochemical test of crude extract indicated positive flavonoids and coumarin. Thin layer chromatography (TLC) analysis with eluent chloroform: methanol gave 2 spots with Rf value of 0.8 and 0.37. Moreover, high performance liquid chromatography (HPLC) analysis showed absorption peak with the highest abundance at the retention time of 12.483 minute and 16.617 minute was 266 nm and 230 nm. According to these of phytochemical, TLC, and HPLC, inhibitor compound from BTM 11 belongs to flavonoids.
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