Judul: Aktivitas Alkalin Fosfatase Serum dan Gambaran Histopatologi Ginjal Tikus yang Diberi Kelapa Kopyor Pascainduksi Parasetamol
Abstrak: The aims of this research were to determine the effects of paracetamol induction and kopyor coconut consumption on the activity of alkaline phosphatase (ALP) and histophatology of rat kidney. These treatments were development of previous findings showing that paracetamol can cause negative effect to the body while kopyor coconut has the ability to improve human health, related with its capacity to prevent oxidative damage of human body. In this research, the positive effect of kopyor is approached through measurement of body weight, the activity of the ALP enzyme of test animals, anatomi pathology, and kidney histophatology. The result shows that paracetamol treatment using toxic dose was found to reduce body weight of test animals. Meanwhile, both kopyor and temulawak were able to counter the negative effect of paracetamol, indicated by the increase in the body weight of test animals. Other results showed that treatments using temulawak and kopyor of 3 time-dose demonstrated a positive effect on ALP serum activity in the kidney significantly as compared to negative control. Furthermore, pathologic observation of the test animals’ kidney showed that kopyor treatment of 3 time-doses was confirmed helping the kidney to recover from negative effect of paracetamol, better than the negative control.
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Judul: Aktivitas superoksida dismutase dan patologi anatomi pada hati tikus dengan perlakuan parasetamol dan suplemen kelapa kopyor
Abstrak: Penelitian ini bertujuan untuk menentukan pengaruh induksi parasetamol dan konsumsi suplemen kelapa kopyor terhadap aktivitas enzim superoksida dismutase (SOD) dan patologi anatomi hati tikus. Perlakuan-perlakuan tersebut merupakan pengembangan literatur sebelumnya, yang menunjukkan bahwa parasetamol dapat berefek negatif terhadap tubuh, sedangkan buah kelapa kopyor memiliki manfaat kesehatan terkait dengan kemampuannya mencegah kerusakan oksidatif di dalam tubuh. Dalam penelitian ini, pengaruh positif dari kopyor ditentukan melalui pengukuran bobot badan (BB) dan aktivitas enzim SOD total hewan coba, yang diinduksi parasetamol dan diberi suplemen kopyor, dengan suplemen temulawak sebagai kontrol positif. Hasil penelitian menunjukkan bahwa pemberian parasetamol dalam dosis toksik mampu menurunkan BB hewan coba. Sementara itu, pemberian suplemen temulawak dan suplemen kelapa kopyor dapat memperbaiki keadaan melalui peningkatan BB hewan coba. Hasil lain menunjukkan bahwa hewan coba yang diberi suplemen temulawak dan suplemen kelapa kopyor 5 kali dosis memperlihatkan perbedaan nyata dalam hal aktivitas enzim SOD total dibandingkan kontrol negatif. Lebih lanjut, pengamatan patologi anatomi pada hati hewan coba menunjukkan bahwa pemberian kelapa kopyor 5 kali dosis terbukti membantu perbaikan hati hewan coba lebih baik dibandingkan dengan kontrol negatif.
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Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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