Judul: Studi Korelasi Antara Proses Geomorfik Dan Pedogenesis Di Desa Lamajang, Kecamatan Pangalengan, Kabupaten Bandung
Abstrak: Landform and soil formed by geomorphic and pedogenic processes. Geomorphic processes play a role in change and shape the earth's surface through out a process of physical and chemical weathering, volcanism, and extraterrestrial, while the pedogenic process produce soil body. According to van Wambeke and Forbes (1986), land unit is a container of a soil unit due to the similarity genetic factors (abiotic and biotic) and the genetic processes. Geomorphic processes based on abiotic factors (parent material, climate, relief, and time), while biotic factors (organisms, especially vegetation) only serves as an indicator, for example: gelam is an indicator of landform with acid sulphate soils. The processes of pedogenic based on factors biotic and abiotic itself. Research areas belong to volcanic landscape which dominated by the surface processes, such as: erosion, deposition, sedimentation, and mass movements, thus forming various forms of landform. This research intends to do analysis, interpretation, and correlation between land formation (geomorphic processes) and soil formation (pedogenesis) in volcanic landscapes. The aim is to determine land units (landforms) systematically (Desaunettes, 1977) as containers of soil units (Soil Survey Staff, 2010). This research includes preparation, field work, laboratory analysis, processing data, and preparation of final report. The results of research showed that the diversity of landforms are coinciding with the diversity of soil units (Great Group). There were found that the landform of ridge plains of volcano midlle, with parent material from andesitic rocks, undissected and flat slope (0-3%) (Vat 3.5.0) is occupied by Melanudand (Pedons P1); Landform of volcano midlle, with parent material from andesitic rocks, dissected and steep slope (30-60%) (Vat 3.6.3) is occupied by Hapludand (Pedons P2); and Landform of foot slope volcanic midlle, with parent material from andesitic rocks, slightly dissected and gently slope (2-5%) (Vat 3.5.2) is occupied by Fulvudand (Pedons P3). Correlation between geomorphic and pedogenesis processes which observed through the toposequent direction, supported by laboratory analysis data and secondary data (Puslittanak, 1993) and then extrapolated to the entire Village Lamajang, resulting seven landform mapping units as the component of semidetailed Landform Map of Lamajang Village Scaled at 1 : 50.000.
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Judul: Diversity of Soil Characteristics along a Land Transect in Two Geological Formations in the Padalarang Region, West Bandung
Abstrak: Suatu transek lahan dapat memiliki keragaman karakteristik tanah karena memiliki beberapa perbedaan dalam faktor pembentuk tanah, tergantung pada komponen yang dominan dalam mempengaruhi proses pembentukkan tanah. Area penelitian yang berlokasi di Desa Padalarang merupakan daerah yang unik dengan kondisi geologi dan relief atau bentuk wilayah yang terbentuk dari perbukitan vulkanik, perbukitan struktural tersier karstik, dan dataran rendah alluvial. Penelitian ini bertujuan untuk menguraikan keragaman karakteristik tanah pada suatu transek lahan yang berada pada perbatasan dua formasi geologi, yaitu formasi geologi tersier batugamping (Tomr) dan formasi kuarter vulkanik tua (Qob) di wilayah Padalarang, Kabupaten Bandung Barat. Pengambilan sampel dan analisis lapang dilakukan di empat titik yang berbeda secara toposekuen di dalam suatu jalur transek yang dipilih berdasarkan peta kontur dan pengamatan lapang. Profil tanah PT-1 mewakili lereng koluvial dari tebing karstik batu kapur dengan kemiringan lereng 55%. Profil PT-2 mewakili lereng alluvial-koluvial dengan kemiringan lereng 28%. Profil PT-3 mewakili lereng alluvial dengan lereng 3%. Profil PT-4 mewakili lereng bawah perbukitan dengan kemiringan 15%. Hasil penelitian mendapatkan bahwa transek lahan di lokasi penelitian mempunyai variasi bahan induk, geomorfik lahan dengan tingkat kemiringan, posisi dan proses transportasi material bahan yang berpengaruh terhadap karakteristik tanah, klasifikasi dan tingkat perkembangan tanah. Bahan induk tanah batugamping berpengaruh terhadap sifat kimia tanah yang berkaitan dengan proses pelarutan batu kapur, dan pengaruhnya terlihat pada kandungan Ca-dd dan pH tanah yang tinggi. Interaksi berbagai faktor pembentuk tanah menyebabkan perbedaan karakteristik tanah dan tercermin dalam klasifikasi tanahnya, dimana profil tanah PT-1 pada lereng koluvial dengan kemiringan sangat curam terbentuk tanah Lithic Eutrudept berdebu halus, campuran, super aktif, hiperthermik, PT-2 pada lereng alluvial-koluvial di bawahnya terbentuk tanah Inceptic Hapludalfs berlempung halus, campuran, super aktif, hiperthermik, PT-3 pada lembah alluvial terbentuk tanah Typic Endoaquepts berdebu halus, campuran, super aktif, hiperthermik, dan PT-4 pada kaki lereng terbentuk tanah Aquic Eutrudepts halus, campuran, super aktif, hiperthermik. Tingkat perkembangan tanah berdasarkan parameter diferensiasi horizon genetik, ketebalan horizon B, perbandingan debu/klei dan rasio KTK/persen klei pada horizon B, terlihat hampir sejalan dimana PT-2 > PT-4 > PT-3 > PT-1. Perkembangan tanah pada profil PT-1 terhambat karena faktor erosi akibat berada pada lereng koluvial yang sangat curam, sebaliknya profil PT-3 dan PT-4 yang berada di lembah atau kaki lereng terhabat oleh faktor drainase tanah., A land transect can have a variety of soil characteristics because it has several differences in soil forming factors, depending on the dominant component in influencing the soil formation process. The study area, which located in Padalarang, is a unique area with geological conditions and relief that were formed from volcanic hills, karstic tertiary structural hills, and alluvial lowlands. This study aims to describe the diversity of soil characteristics on a land transect located on the border of two geological formations, namely a limestone tertiary formation (Tomr) and an old quaternary volcanic formation (Qob), in Padalarang, West Bandung Regency. Sampling and field analysis were carried out at four different toposequence sites on a transect line selected based on the contour map and field observation. Soil profile of PT-1 represents the colluvial slope of a karstic limestone cliff with a slope of 55%. PT-2 represents the
Keyword: Land transect, Limestone and Old Volcanic Formation, Soil Classification and Development

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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