Judul: Potensi Antioksidan dan Antikanker Ekstrak Batang Lelutung Tokak (Tabernaemontana macrocarpa Jack.)
Abstrak: The purpose of this research was to determine the activity of n-hexane, ethylacetate, ethanol and water extracts of Lelutung Tokak (Tabernaemontana macrocarpa Jack.) as antioxidation and anticancer. This research consisted of four steps, the first step was extration and phytochemistry. The second step was Brine Shrimp Lethality Test (BSLT) to determine the toxicity of the extract. The third step was examination of antioxidation activity using DPPH method and the last step was examination of anticancer activity of the extract using L1210 leukimia cell line. The results of this research showed that four extract of stem of T. Macrocarpa Jack. has antioxidation and anticancer activity. The LC50 of BSLT was hexane extract 567,886 ppm; ethyl acetate extract 119,339 ppm; ethanol extract 120,56 ppm and water extract 156,441 ppm. The IC50 of antioxidation activity using DPPH method was hexane 653,540 ppm; ethyl acetate 48,103 ppm; ethanol 53,322 ppm and water 121,019 ppm. Furthermore the most active extract which was tested as anticancer. The IC50 of anticancer test was ethyl acetate extract of 6,039 ppm; ethanol extract of 7,145 ppm. The result of phytochemistry analysis showed four extract of stem of T. macrocarpa Jack. contains alkaloid, flavonoid, saponin and tanin compounds. The conclusion of this experiment wasethylacetate and ethanolextract have a strong anticancer and antioxidation activity.
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Judul: Potensi antioksidasi bebrapa ekstrak senyawa bahan alam yang berkhasiat sebagai antikanker
Abstrak: This research was conducted to compare antioxidation potency of some extracts from natural materials compound ivhich have anticankr poiency. The natural compounds tested were ex&& of mohkota dewa, d m d k a , sahbung nyawa, temuputih, and tofu whey. Analysis have been done using 200 ppm total an centration for each extract tested. Natural antioxidant vitamin E (a-tocopherol 0 ppm) is used for comparison. The degree of oxidation was measured by $Ilobarbituric acid (TBA) method in vitro.
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Judul: Infeksi Virus Parainfluenza Pada Anjing
Abstrak: Virus parainfluenza anjing termasuk famili Paramyxoviridae, berbentuk pleomorf dengan ukuran bervariasi (bergaris tengah antara 100-500 nm), berpembungkus peka ether, berisi genom RNA dan secara serologis mempunyai kesamaan dengan virus SV-5 kera; dikenak sebagai salah satu kausa penting dari sindrom "kennel cough". Infeksinya dapat mengenai anjing semua umur yang belum pernah terinfeksi atau mendapatkan vaksinasi mengakibatkan gejala klinis ringan yang terbatas pada traktus respirasi atu infeksi yang secara klinis tidak memperlihatkan gejala nyata. Gejala klinis yang nampak setelah masa inkubasi (1-5 hari) terlewati berupa batuk yang tidak berat selama beberapa hari, berbagai tingkat tonsilitis dan pharyngitis dan kadang-kadang ditemukan kenaikan temperatur rektal antara 1-2 derajat C dari temperatur normal rat-rata. Anjing terinfeksi mengandung virus pada traktus respirasi bagian atas dan bawah serta limfonoduli sampai hari ke 9 setelah infeksi. Penyebaran virus antar anjing terjadi secara aerogen.
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