Judul: Fraksionasi miristisin dari minyak atsiri pala (Myristica fragrans Houtt) sebagai pelangsing aromaterapi secara in vivo
Abstrak: Nutmeg is a spice plant native of Indonesia that contains essential oils, including myristicin as the main psychoactive compound. In this study, myristicin was fractionated from nutmeg essential oil and analyzed for its potency as slimming aromatherapy with in vivo assay. Nutmeg essential oil was fractionated by using column chromatography resulting fraction 5 (F5) having similar chromatogram pattern to myristicin standard. Nutmeg essential oil, F5, and α- pinene were then analyzed by gas chromatograph-mass spectrometer, and the slimming aromatherapy potencies were studied on white adult male Sprague- Dawley rats. Inhalation of nutmeg essential oil, F5, and α-pinene for 30 days showed lower percentage of body weight gain compared with positive control group (high fat and cholesterol feed) although the differences were not significant. Rats treated with nutmeg essential oil and F5 inhalation showed the lowest body weight gain responses, 9.18 and 9.45% (w/w), respectively. However, nutmeg essential oil and F5 were not potential as slimming aromatherapy yet.
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Judul: Fraksionasi senyawa aktif minyak atsiri jahe sebagai pelangsing aromaterapi secara in vivo
Abstrak: Ginger is an Indonesian aromatic plant containing essential oil. The objectives of this research were to separate constituents of ginger essential oil and to evaluate the active components as aromatherapy for obesity using in vivo analysis. The essential oil was collected by steam distillation method as much as 1.57% (w/v) from ginger rhizomes. Fractionation of the essential oil was performed by silica gel column chromatography (gradient elution) resulting 11 fractions. Fraction 2, fraction 4, and ginger essential oil were analyzed for their activities as aromatherapy for antiobesity in vivo by using male Sprague-Dawley rats. Inhalation of fraction 2, fraction 4, and ginger essential oil showed lower response of rats body weight compared with the positive control (high cholesterol feed). From the three groups of rats, the essential oil inhalation group gave the lowest response for body weight increment, that is 6.17% (w/w). Based on gas chromatograpy-mass spectrometry analysis, the main component in ginger essential oil which affected the body weight of rats was camphene
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Judul: Closed Knight’s Tour pada Papan Catur Berbentuk Persegi Panjang dengan Ukuran Maksimal 8 × 8
Abstrak: Closed Knight’s Tour merupakan langkah kuda yang mengunjungi setiap kotak pada papan catur tepat satu kali dengan langkah kuda berawal dan berakhir pada kotak yang sama. Graf yang terbentuk dari closed knight’s tour dinotasikan sebagai graf G(m,n), dengan m adalah banyaknya baris dan n adalah banyaknya kolom. Graf tersebut memuat Hamiltonian cycle. Sebuah graf terhubung G adalah graf bipartite jika dan hanya jika graf tersebut tidak memiliki cycle dengan panjang ganjil. Papan catur yang memenuhi syarat cukup untuk memiliki closed knight’s tour adalah papan catur berukuran 5 × 6, 5 × 8, 6 × 6, 6 × 7, 6 × 8, 7 × 8, dan 8 × 8.
Keyword: bipartite, closed knight’s tour, hamiltonian cycle, knight’s tour, teori graf