Judul: Pembangunan Spatiotemporal Data Model pada Tipe Data Vektor dengan Konsep Event-based Spatiotemporal Data Model (ESTDM)
Abstrak: Spatiotemporal data are spatial data with well-defined spatial, area, and location information, as well as temporal attribute (time). Various types of changes to the spatiotemporal data require a data model to store this information. This research constructed a data model for spatiotemporal data with event-based spatiotemporal data model (ESTDM) concept that can store the cause of spatiotemporal data changes, type of changes, and action of changes conducted by spatial objects. The used data were land surface area in Indonesia in 1994 and 2001 in the form of polygon vector data. The data were processed by the ESTDM concept in order to produce an appropriate data model that can provide the necessary information with spatiotemporal query analysis. There were eight spatiotemporal queries that were used to analyze the object changes, in the form of contain, overlap, and coveredby. It was found that the application of event-based spatiotemporal data model concept on the polygon data type requires a more diverse type of data in terms of spatial changes and longer observation time. Other spatiotemporal queries may be used to improve the proposed data model.
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Judul: Implementasi Operator Temporal dan Spasial pada Data Spatiotemporal
Abstrak: The spatio-temporal data models and query languages have received much attention in the database research community because of their practical importance and the interesting technical challenges they pose. The previous research has successfully implemented temporal and spatial operator to retrieve specific information of spatio-temporal data, but only an example data was used. In this research, the implementation of the temporal and spatial operator using real data was shown. There were two data used, namely the land cover data in Kalimantan island from 2000-2009, and land use data in some region of Indonesia from 1994 and 2001. The research complexity increased because of the different attributes of real data as compared with example data. The method in this research consist of data preprossesing, temporal operator implementation, spatial operator implementation, spatio-temporal operator implementation, and testing. The preprocessing include data cleaning, and data model transformation. The temporal operator used in this research were history, after, before, when, between, first, last and past. Meanwhile, the spatial operator used were intersection, equal, touches, cover, coveredby, distance, overlap, contain and within. The result showed that the spatio-temporal operator can produce a more spesific information retrieval rather than that without using spatio-temporal query. The research also verified that spatio-temporal operator can be used in real problems
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Judul: Inhibisi Biosintesis Kolesterol Oleh Campuran Ekstrak Flavonoid Berbasis Daun Jabon Merah (Anthocephalus Macrophyllus) In Vitro
Abstrak: Anthocephalus macrophyllus yang dikenal dengan nama jabon merah mulai dikembangkan sebagai tumbuhan herbal dan telah dilaporkan memiliki daya inhibisi terhadap aktivitas enzim HMG-KoA reduktase, namun belum ada informasi ilmiah mengenai campuran ekstrak flavonoid berbasis daun jabon merah dalam menghambat aktivitas enzim tersebut. Penelitian ini bertujuan menguji potensi campuran ekstrak flavonoid berbasis daun jabon merah dalam menghambat biosintesis kolesterol in vitro. Enzim HMG-KoA reduktase (EC 1.1.1.34) merupakan enzim kunci yang meregulasi tahap awal biosintesis kolesterol. Penghambatan aktivitas enzim tersebut diukur dengan spektrofotometer pada panjang gelombang 340 nm menggunakan kit enzim HMG-KoA reduktase (No. CS1090) dari Sigma Aldrich. Hasil menunjukkan penghambatan aktivitas enzim terbesar terjadi pada ekstrak formula D sebesar 25%. Penghambatan tersebut masih lebih rendah daripada standar flavonoid rutin (60.17%) dan kuersetin (41.10%), tetapi sama baiknya dengan pravastatin komersial (18.64%) sebagai obat antikolesterol. Oleh karena itu, ekstrak formula D berpotensi untuk dikembangkan sebagai obat antikolesterol.
Keyword: Anthocephalus macrophyllus, antikolesterol, flavonoid, Guazuma ulmifolia, HMG-KoA reduktase