Judul: Effectiveness of Combined Leaf Decoction of Keji Beling (Strobilanthes crispa (L.) Blume) and Kentutan (Paederia foetida) Plants as Antidiarrheals in Mice
Abstrak: Diare masih menjadi masalah kesehatan utama di negara berkembang. Keanekaragaman hayati yang tinggi di Indonesia, menjadi peluang penggunaan herbal sebagai salah satu solusi pengobatan diare. Herbal memiliki banyak kandungan nutrisi, mineral, dan senyawa aktif yang memiliki efek antidiare seperti tumbuhan keji beling dan kentutan. Penelitian ini bertujuan mengetahui efek dan konsentrasi terbaik antidiare dari kombinasi dekok daun keji beling dan kentutan. Kelompok perlakuan terdiri dari kelompok kontrol negatif, kelompok kontrol positif (loperamid) dan kombinasi dekok (konsentrasi 100%, 50%, 25%, dan 12,5%). Metode yang digunakan adalah proteksi dan transit intestinal pada mencit. Induksi diare menggunakan oleum ricini. Hasil penelitian menunjukkan bahwa kombinasi dekok kedua tanaman dapat menurunkan motilitas usus, mempertahankan konsistensi feses, dan memiliki nilai rasio transit intestinal yang baik. Konsentrasi 50% memiliki hasil terbaik., Diarrhea is still a major health problem in developing countries. The high biodiversity in Indonesia is an opportunity for the use of herbal plants as a solution for treating diarrhea. Herbal plants contain many nutrients, minerals, and active compounds that have anti-diarrheal effects, such as keji beling and kentutan plant. This study aims to determine the effect and the best concentration of antidiarrheals from the combination of leaf decoction of keji beling and kentutan. The group consisted of a negative control group, a positive control group (loperamide), and decoction combination (100%, 50%, 25%, and 12,5% concentrations). The method used is intestinal protection and transit in mice. Diarrhea is induced using oleum ricini. The results showed that the combination of decoction of the two plants could reduce intestinal motility, maintain stool consistency, and have a good intestinal transit ratio. The decoct concentration of 50% has the best results.
Keyword: diarrhea, keji beling, kentutan, intestinal protection, intestinal transit

Judul: The Effectiveness of Keji Beling (Strobilanthes crispus Blume)  Leaf Infusion as Antidiarrheal in Mice (Mus musculus)
Abstrak: Tanaman keji beling telah lama digunakan untuk pengobatan penyakit pada manusia, namun penelitian terkait manfaat tanaman keji beling sebagai antidiare masih sedikit. Tujuan penelitian ini adalah mengevaluasi secara ilmiah efek infusa daun keji beling sebagai antidiare dengan metode proteksi intestinal dan transit intestinal pada mencit. Penelitian ini menggunakan 36 ekor mencit yang dibagi menjadi enam kelompok terdiri dari kelompok kontrol negatif (Tween 80 [1%]), kontrol positif (suspensi loperamid HCl), dan empat kelompok perlakuan infusa daun keji beling dengan konsentrasi 12,5%, 25%, 50%, dan 100% yang diberikan secara oral. Parameter yang diamati yaitu frekuensi defekasi, konsistensi feses, dan rasio lintasan marker usus. Berdasarkan metode proteksi intestinal, infusa daun keji beling dengan konsentrasi 12,5%, 25%, dan 50% memiliki efek antidiare, sedangkan pada metode transit intestinal hanya infusa daun keji beling konsentrasi 50% yang memiliki efek antidiare. Berdasarkan kedua metode, infusa daun keji beling konsentrasi 50% menunjukkan efek antidiare yang paling efektif., Keji beling plant has long been used for the treatment of diseases in human, but research regarding the benefits of the keji beling plant as an antidiarrheal are still few. The purpose of this study was to evaluate scientifically the effect of keji beling leaf infusion as an antidiarrheal with intestinal protection and intestinal transit method in mice. This study used 36 mice which were divided into six groups consisting of a negative control group (Tween 80 [1%]), a positive control group (loperamide HCl suspension), and four groups of treatment with a keji beling leaf infusion concentration of 12,5%, 25%, 50%, and 100% given orally. The parameters observed were the frequency of defecation, the consistency of faeces, and the ratio of marker passages in the intestines of mice. Based on intestinal protection method, infusion of keji beling leaf with concentrations of 12.5%, 25%, and 50% has an antidiarrheal effect, while in the intestinal transit method only the infusion of keji beling leaf with concentration of 50% has an antidiarrheal effect. Based on the two methods, infusion of keji beling leaf at a concentration of 50% showed the most effective antidiarrheal effect.
Keyword: antidiarrhea, intestinal protection, intestinal transit, Strobilanthes crispus

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
Keyword: