Judul: Perubahan Garis Pantai Selatan Jawa Kabupaten Kebumen, : Jawa Tengah
Abstrak: The study of shoreline changes during the years 2002 - 2012 was conducted in the South Coast of Kebumen, Central Java, using a principle of sediment budget on a cell along the coast. Alongshore sediment transport calculations was done by considering the influence of the wind as the main generating waves in the deep ocean. Sediment transport calculation results showed that the dominant sediment transport was to the east at the time of the waves coming from the southwest and west and to the west when dominant waves propagated from the southeast. However, in general the dominant sediment transport was to the west. The comparison of the shoreline profile between of model results and satellite imagery showed similarity. The difference mainly occurs in the curving shape of the coasline, which probably due to external factor such as human activities which were not considered in the model. The dominant processes occurring on the study area was abrasion or deterioration along the coast. The results showed that abrasion value was greater than the accretion, value i. e., abrasion was around 86.45 meters and accretion was about 74.21 meters.
Keyword: shoreline changes., waves, sediment transport, accretion, abrasion

Judul: Perubahan garis pantai dari pantai Teritip Balikpapan sampai pantai Ambarawang Kutai Kertanegara Kalimantan Timur
Abstrak: Shoreline change from coast of Teritip Balikpapan to coast of Ambarawang Kutai Kertanegara, East Kalimantan from 2000 – 2007 was analyzed by developing a model. Initial shoreline as an input for model was the result of Landsat image in 2000, and the shoreline from Landsat ETM in 2007 was used to compare the final result of model. The model predicts shoreline change due to along shore sediment transport generated by wave that brakes at the shoreline. The characteristics of broken waves was predicted by analysing wave transformation from off-shore sea where the wave was generated by winds. Sediment transport along the coast were mostlynortheastward as the main winds that blown toward the coast were mostly from the south. Simulation for 8 years showes that accretion more intensive in the northern part than those in the south. In general, shoreline shape resulting from model show a good resemblace to those from Landsat image in 2007. Discrepancies between the two shoreline shape occurred mostly at the upstream of the head land where results of model shows erosion but the images show the shoreline almost stable. This is perhap due to existance of mangrove that prevent erosion, but the effect of this vegetation is not included in the model.
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Judul: Isolasi dan purifikasi inhibitor RNA helikase virus hepatitis C dari bakteriosin bakteri asam laktat S34
Abstrak: Target molecular therapy is one of method to prevent hepatitis C virus which was developed recently. NS3 Helicase/RNA helicase hepatitis C virus inhibition using inhibitory peptide are target in molecular therapy. Bacteriocin are inhibitory peptides which can inhibit hepatitis C virus through inhibition of NS3 helicase. Bacteriocin is a peptide which is produced by lactic acid bacteria. The aim of this research were to isolate and to purify bacteriocin from S34 lactic acid bacteria which has high activity to inhibit RNA helicase of hepatitis C virus. S34 lactic acid bacteria were identified using 16S RNA amplification and DNA sequencing identification of S34 lactic acid bacteria was Lactobacillus plantarum WCFS1. The bacterial growth reached logaritmic phase at 7 hours and stationary phase at 10 hours. Bacteriocin were isolated and purified by ammonium sulphate precipitation with 80% saturation, gel filtration chromatography, and characterization of bacteriocin through molecular weight analysis and measured protein concentration. Bacteriocin from S34 lactic acid bacteria were included in 2nd class bacteriocin, had 64.20 % of inhibition against RNA helicase hepatitis C virus, had molecular weight about 1.7-4.2 kDa, and specific activity in the amount of 2.84 x 106 U/mg.
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