Judul: Perilaku makan dan aktivitas fisik anak TK berstatus gizi lebih dan gizi baik di Kota Bogor
Abstrak: Tujuan umum penelitian ini adalah membandingkan perilaku makan dan aktifitas fisik antara anak TK berstatus gizi lebih dan gizi baik di Kota Bogor. Tujuan khusus penelitian ini adalah (1)menguraikan persepsi ibu tentang ukuran tubuh (berat badan) anak,(2)membandingkan perilaku makan antara anak TK berstatus gizi lebih dan gizi baik, (3) membandingkan aktifitas fisik antara anak TK berstatus gizi lebih dan gizi baik, serta (4) menguji hubungan perilaku makan dan aktivitas fisik dengan status gizi anak.
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Judul: Pengetahuan Gizi, Konsumsi Pangan Sumber Serat dan Aktivitas Fisik pada Siswa Sekolah Dasar Berstatus Gizi Lebih di Kota Bogor.
Abstrak: Tujuan dari penelitian ini adalah menganalisis pengetahuan gizi, konsumsi pangan sumber serat dan aktivitas fisik pada siswa sekolah dasar berstatus gizi lebih di Kota Bogor. Desain penelitian yang digunakan adalah cross sectional study. Penelitian dilakukan di 3 Sekolah Dasar Islam Terpadu (SDIT) di Bogor. Contoh dipilih secara purposif sebanyak 107 siswa (7 siswa overweight, 70 siswa obese, 30 siswa severe obese) kelas V dan VI. Rata-rata nilai pengetahuan gizi contoh 68.4±14.8 dan sebagian besar berkategori sedang (59.8%). Rata-rata asupan serat contoh 5.9±1.8 g dan sebagian besar berkategori kurang (99.1%). Rata-rata nilai PAL contoh adalah 1.47±0.19 dan sekitar separuh aktivitas fisik contoh berkategori ringan. Hasil penelitian menunjukkan adanya hubungan signifikan antara usia dengan status gizi, aktivitas fisik dengan status gizi, usia dengan pengetahuan gizi, pengetahuan gizi (aspek makanan sehat) dengan asupan serat dan pengetahuan gizi (aspek gizi lebih) dengan asupan serat.
Keyword: aktivitas fisik, gizi lebih, konsumsi pangan sumber serat, pengetahuan gizi

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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