Judul: Potensi Teh Herbal Lempuyang Gajah (Zingiber zerumbet L.) sebagai Antioksidan pada Tikus Sprague-Dawley Hiperkolesterolemia
Abstrak: Hypercholesterolemic conditions can increase lipid peroxidation and as an indicator of the presence of free radicals in the body. This research aimed to determine the efficacy of lempuyang gajah (Zingiber zerumbet L.) herbal tea as an antioxidant to prevent lipid peroxidation in hypercholesterolemic rats. Twenty six rats were divided into 4 following groups: normal, hypercholesterolemia, extract 1 (low dose), and extract 2 (high dose) groups. Hypercholesterolemia were induced in rats by high cholesterol diet (1.5% cholesterol) and oral administration of propil tiourasil (PTU) 0.5 mg/kg bw in six weeks. Before necropsied, rats were given standard diet for the last four weeks. Lipid peroxide concentrations in the liver were analyzed using thiobarbituric acid (TBA) assay with spectrofotometer UVVis at 532 nm. Results showed that feeding cholesterol free diet in the last four weeks normalized liver lipid peroxide concentration in the three treatment groups. The average of all groups were 40.88±13 nmol/g (p=0.317). Addition of extract reduced correlation between liver lipid peroxide concentration and blood cholesterol concentration on the extract groups (1 and 2). This observation suggest that components of lempuyang gajah herbal tea can prevent lipid peroxidation in liver.
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Judul: Potensi Antihiperkolesterolemia Ekstrak Seduhan Teh Herbal Lempuyang Gajah (Zingiber zerumbet L.)
Abstrak: The objective of this research was to study the effectivity of herbal tea compositions of lempuyang gajah as antihypercholesterolemic agent. Extracts were tested in Sprague-Dawley male rats. Forty six rats were divided into four experimental groups as follow: normal, hyperlipidemic, herbal tea extract 1, and herbal tea extract 2. Rats were made hiperlipidemic by oral administration of propil tiouracil (0.5 mg/Kg BW) and high cholesterol feeding (1.5 % cholesterol). Total blood cholesterol concentrations were measured by cholesterol oxidase enzymatic methods of ‘CHOD-PAP’ using spectrophotometer at wavelenght 500 nm. Results showed that cholesterol diet increased blood cholesterol concentration by 76.11 % (p=0.004). Following free cholesterol diet (washed out period), blood cholesterol concentration was decreased by 43.82 % (p=0.101). Similarly, extract 1 reduced cholesterol concentration by 43.20 % (p=0.005). Antihyperlipidemic potency of extract 2 is higher than extract 1 as shown by significant reduction of cholesterol by 51.70 % (p=0.000).
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Judul: Pembangunan Perumahan Pada Wilayah Desakota Kaitannya Dengan Sistem Sosial Masyaraka t Asli
Abstrak: Faktor utama yang banyak mempengaruhi meningkatnya jumlah perumahan dan pemukiman pacta wilayah desakota adalah adanya tekanan populasi sebagai akibat dari migrasi besar-besaran menuju daerah desakota. Dengan kata lain, lokasi perumahan atau pemukiman menjadi tak memiliki banyak pilihan lagi, kota telah sesak dan sasaran selanjutnya para pengais materi di daerab kota adalab wilayah desakota. Masyarakat asli yang sejak lama tinggal di wilayah desakota merupakan bagian dari masyarakat desakota yang perlu diperhatikan. Baik disadari maupun tidak disadari, perubaban pada masyarakat asli desakota akan terjadi karena masyarakat selalu dalam keadaan dinamis. Selain itu perubahanjuga akan terjadi dikarenakan masyarakat adalah sistem yang terdiri dari bagian-bagian yang berhubungan serta berintegrasi secara fungsional, sehingga perubaban pada satu fungsi dari masyarakat akan mempengaruhi fungsi lainnya.
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