Judul: Model Kinetika Reaksi Nanopartikel Ketoprofen Tersalut Gel Kitosan-Alginat Berdasarkan Uji Disolusi secara In Vitro.
Abstrak: Modification of chitosan gel by natural hydrogels such as alginate with trypolyphosphate (TPP) crosslinker are potential to be applied as good coating materials in drug delivery system. Most of the drug delivery system studied, however still in micro size. Therefore in this study, chitosan-alginate gel with TPP crosslinker was used to coat ketoprofen in nanocapsules by using spray drying method with variation of chitosan, alginate, and TPP concentration. The kinetic reaction model was determined based on in vitro dissolution test. The size of nanoparticles obtained in this study was about 220–8857 nm. The dissolution test showed that ketoprofen coated by chitosan-alginate crosslinked with TPP had controlled release in acid medium and maximum release in base medium. In general, the ketoprofen releasing kinetic model followed Higuchi, Korsmeyer- Peppas, and Hixson-Crowell equations.
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Judul: Perilaku disolusi nanokapsul ketoprofen tersalut gel kitosan-alginat  secara in vitro
Abstrak: Modified chitosan has been used as coating agent. Chitosan-alginate gel is potential to be applied as coating agent in drugs delivery system. Dissolution result indicates that chitosan-alginate membrane is the best in coating ketoprofen, but the microcapsule is still too big to be used. This study used 9 formula nanocapsule ketoprofen dissolution coated by chitosan-alginate gel. The Tween 80 solution concentrations used in the process were 1, 2, and 3% (v/v). The maximum ketoprofen releasing rate was observed at the addition of 2% Tween 80 solution. Four ketoprofen releasing mechanism were studied, i.e zero order release, first order release, Higuchi, Hixson-C, and Koremeyer-Peppas. The kinetic model in general follows Korsmeyer-Peppas model.
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Judul: Ekologi merak hijau jawa (Pavo muticus muticus) Linnaeus 1758 pada beberapa tipe habitat di Ujung Timur Penyebarannya Jawa Timur, Indonesia
Abstrak: Merak hijau jawa merupakan salah satu jenis burung yang dilindungi.di Indonesia berdasarkan SK Mentan No 66/Kpts/Um/2/1973 dan Peraturan Pemerintah Republik Indonesia No 7 tahun 1999. Menurut ICBP (The International Council for Bird Preservation) merak hijau sebagai jenis burung yang tergolong terancam secara keseluruhan (globally threatened) baik populasi maupun habitatnya, sedangkan CITES mencantumkan merak hijau ke dalam Appendix II, merak hijau dari alam tidak bisa langsung diperdagangkan dan BirdLife International (2007) memasukkan golongan burung yang endangered. Tekanan terhadap populasi dan habitat merak hijau jawa sangat besar, sehingga kondisi populasinya menurun pada setiap penyebaran lokalnya, habitatnya terfragmentasi bahkan terisolasi. Tekanan terhadap populasi terutama karena perburuan liar. Namun demikian fakta menunjukan bahwa merak hijau jawa masih ada (exist), hal ini memberikan gambaran bahwa burung ini tentunya memiliki strategi ekologi tertentu untuk tetap bertahan hidup di alam pada berbagai tipe habitat.
Keyword: Pavo muticus muticus, Call count transect method, Pavo cristatus, Pavo muticus, Pavo muticus spicifer, Pavo muticus imperator, Pavo muticus muticus, Javan Green Peafowl, East Java