Judul: Strategi BKP5K dalam Menunjang Penganekaragaman Pangan di Kabupaten Bogor
Abstrak: The purposes of this research are (1) to identify internal and external factors of BKP5K in order to support food-diversification in Bogor (2) to formulate alternative strategies (3) to formulate the priority of strategies by architercture strategy approach. Analytical instruments used are internal and external analysis, SWOT matrix, and architecture strategy. The obtained strategies are optimalization of food security development council in subdistrict level; BKP5K’s budget is focused in food security establishment; initiation of food production area based on the subdistrict’s potential; formulating the policy of area management by the manager; formulating the policy of trading agreement between food production area; guiding and training all staffs; formulating the policy food production area institution is cooperative; formulating the policy of transferring the development of one commodity to another one; formulating the policy to infiltrate local food knowledge in elementary up to high school curriculum; formulating the policy of development food storage; and formulating the policy of development food information system. Architecture strategy arranges the priority strategy implementation, main stakeholders, up to program which is supporting strategy.
Keyword: SWOT analysis., Kabupaten Bogor, food consumption diversification, BKP5K, architecture strategy

Judul: Analisis Preferensi Pangan Masyarakat Dan Daya Dukung Gizi Menuju Pencapaian Diversifikasi Pangan Kabupaten Bogor
Abstrak: General objective of this study is to analyse Community’s Food Preference and nutritional carrying capacity in the direction of food diversification achievement in Bogor Regency. The spesific objectives are (1) to analyse individual characteristic sample i.e. last education, salary per capita, expenditure per capita, (2) to identify environment characteristic i.e. number of family, job, information from mass media, and production, (3) to identify food preference, (4) to analyse the correlation between food preference with individual and environment characteristic, (5) to analyse local food’s production and preference. Design of this study was cross sectional study with cluster analysis and simple random sampling. Number of sample is 106 for two region characteristics. Data were analized by Microsoft Excel and SPSS 16.0 for Window. Food preference of Bogor Regency community shows that almost sample like to 9 food groups in Desireable Dietary Pattern. The reason of this food preference is food factor (taste, nutrition content, food processing). Local food potential in order to reach food diversification consider to food preference and production. It also an alternative way to fulfill carbohidrat, animal and plant based protein, vitamin and mineral needs. Output of Chi square dan Spearman analysis show that almost food don’t have correlation (p>0.05) with individual and environmental characteristic. Potensial local food based on food preference and production as alternative food for food diversification i.e. corn, cassava, sweet potato, taro (carbohydrate sources): fish, mung bean, tempe, tofu (protein sources); and green leaf vegetables, cow peas, banana and guava (vitamins and minerals sources). Production data shows that corn, fish, mung bean, and soybean production need to be increased its production or import from the other region, especially in West Java. This analysis need to support food preference and by itself it will also support food diversification.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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