Judul: Studi Histopatologi Ginjal Tikus yang Diinduksi Etilen Glikol: Pengaruh Infusum Daun Alpukat (Persea americana Mill.)
Abstrak: The objective of this research was to study the histopathological lesions of rat kidneys induced by ethylene glycol and treated by avocado leaves infusum. This research is continuation of Adha’s experiment (2009) with the experimental design as follows: twenty male rats were divided into four groups, namely the control negative (KN) were received just drinking water ad libitum, the positive control (KP) were induced by 0.75% ethylen glycol and 2% ammonium chloride (inducer), the treatment group I (IF5) were induced and treated by 5% avocado leaves infusum at a dose of 3 ml/200 g BW,and the treatment group II (IF 10) were induced and treated by 10% avocado leaves infusum (3 ml/200 g BW). Treatment was given for 10 days, at day-11 rats were euthanasid, and kidney organs were taken for histopathological study and stained with Hematoxylin- Eosin. The histopatological study showed glomerular edema; hyaline droplet, deposition of protein and tubular necrosis. Percentage of glomerular edema of all treatment groups were not significantly different (p>0.05) compared with negative control group, while the percentage of tubular necrosis of positive control group was significantly different (p<0.05) compared with negative control group. Treatment with avocado leaves infusum can reduce the percentage of necrotic tubulus whereas doses of infusum tend to decrease precentage in protein deposition, hyaline droplet and tubular necrosis. Percentage decrease in tubular damage caused by the avocado leaves flavonoid activity as diureticum and antioxidants.
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Judul: Aktivitas Ekstrak Daun Alpukat Terhadap Perbaikan Ginjal Tikus Akibat Induksi Etilen Glikol
Abstrak: Based on data from WHO been 80% of world population has been used plant extract as a medicine. The objective of this research was to study the histopathological lesions of rat kidneys induced by ethylene glycol and treated by ethanol extract of avocado leaves. This study is a continuation of Adha’s experiment (2009) with the experimental design as follows: 20 male rats were divided into four groups, negative control group (KN) who were given only distilled water, positive control group (KP), which provided adlibitum inducer, the first treatment group (E100) is given inducer and avocado leaves ethanol extract dose of 100 mg/kg BB, and the second treatment groups were given inducer and avocado leaves ethanol extract dose of 300 mg / kg BW. Treatment was given for 10 days, at day-11 rats euthanized, and kidney organs were taken for histopathology and stained with Hematoxylin-Eosin. The histopathological study showed edema, protein deposition, hyaline droplets and tubular necrosis. Statistical analysis showed that administration of ethanol extract of avocado leaves could not reduce the incidence of glomerular edema, hyaline droplet and protein deposition of tubules, but it can significantly inhibit the formation of tubular necrotic. Ethanol extract of avocado leaves contain flavonoids that work as antioxidants and diureticum that can inhibit the formation of tubular necrotic.
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Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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