Judul: Gambaran Imunohistokimia Antioksidan Superoksida Dismutase pada Jaringan Hati Tikus Diabetes Mellitus yang diberi Virgin Coconut Oil (VCO).
Abstrak: Virgin coconut oil atau minyak kelapa murni saat ini umum digunakan antara lain untuk pengobatan beberapa penyakit. Secara empiris dilaporkan, minyak kelapa murni bermanfaat dalam menurunkan kadar glukosa darah. Penelitian ini bertujuan untuk melihat pengaruh pemberian minyak kelapa murni/VCO terhadap profil antioksidan intraseluler copper,zinc-superoxide dismutase (Cu, Zn-SOD) pada jaringan hati tikus diabetes mellitus. Kondisi diabetes mellitus didapat dengan cara induksi alloxan yang dapat merusak sel β Pulau Langerhans. Sebanyak 25 ekor tikus jantan galur Sprague dawley dikelompokkan menjadi 5 kelompok, yaitu (1) kelompok kontrol negatif (K-), (2) kelompok kontrol positif/diabetes (K+), (3) kelompok diabetes dengan pemberian VCO A (VA), (4) kelompok diabetes dengan pemberian VCO B (VB), (5) kelompok diabetes dengan pemberian minyak goreng (MG). Dosis aquadest, VCO, dan minyak goreng yang diberikan 5ml/ekor/hari selama 28 hari. Jaringan hati diambil di akhir perlakuan lalu diproses dengan metode embedding paraffin. Potongan jaringan hati diwarnai dengan Hematoxylin Eosin (HE) dan imunohistokimia terhadap Cu,Zn-SOD. Pemberian VCO menunjukkan gambaran morfologi hati yang lebih baik dibandingkan dengan kelompok kontrol positif dan kelompok minyak goreng. Pemberian VCO dapat meningkatkan kandungan Cu,Zn-SOD pada jaringan hati tikus diabetes mellitus dibandingkan dengan kelompok kontrol positif dan minyak goreng. Pemberian VCO A menunjukkan profil antioksidan Cu,Zn-SOD yang lebih baik dibandingkan kelompok perlakuan VCO B.
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Judul: The effect of virgin coconut oil (VCO) on the profile of immunohistochemical antioxidant superoxide dismutase (SOD) in the kidney of diabetes mellitus rat.
Abstrak: The aim of this research is to evaluate the effect of virgin coconut oil (VCO) on the profile of copper zinc-superoxide dismutase (Cu,Zn-SOD) in the kidney tissue of rats. A total of 25 male white rats (Rattus novergicus), Sprague Dawley were used for this study. They were divided into 5 groups ; (1) negative control group (K-), (2) positive control/diabetic rats group which was orally treated with aquadest (K+), (3) diabetic rats treated with VCO A (VA), (4) diabetic rats treated with VCO B (VB), (5) diabetic rats treated with coconut oil (MG). Diabetic condition was achieved by alloxan injection (IP, 110 mg/kgBW). The dose of aquadest, VCO, and coconut oil was 5ml/rat/day. The treatment were done for 28 days. The kidney were obtained at the end of treatment and then processed using paraffin embedding standard methods. The tissue were then stained with Hematoxillin-Eosin and immunohistochemical technique for Cu,Zn-SOD. The kidney tissues of diabetic rats group treated with VCO showed better morphological feature and higher content of Cu,Zn-SOD compared to that of diabetic rats group treated with aquades only or coconut oil. The treatment of VCO A gave better effect on the profile of antioxidant Cu,Zn-SOD compared to VCO B. Key words : Virgin coconut oil, diabetes mellitus, superoxide dismutase (SOD), kidney, rat
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Judul: Pengembangan Aplikasi Pencarian Tempat Berbasis Mobile
Abstrak: Searching for a room in the building at a new area or even a frequently visited area may be a problem for some people. The purpose of this research is to develop a location based services (LBS) application which can search a place with the user’s current position as a reference. Place in this research is a room inside the building, such as classroom, laboratory, and auditorium. This research is conducted in several stages, the first is application development planning based on related references. The second is system requirement analysis, such as hardware specification and data. After that, the system is designed and implemented based on the previous two iterations of analysis, and finally, the system is tested for each function. The application is developed on Android platform using Google Maps API version two. User’s location coordinate is obtained by using assisted global positioning system ( A-GPS ) which can utilize the services from the service provider to determine the user's position at current time. This research’s result is an application that capable to show a route to the desired room along with its associated distance, travel time and room layout information.
Keyword: room search, place search, location based service, Google Maps Api, Android