Judul: Prenatal Testosterone Exposure to Socio-Cognitive Ability and Digit Ratio (2D:4D) in IPB University Students
Abstrak: According to the Empathizing-Systemizing Theory, higher levels of prenatal testosterone improve the ability to analyze complex systems while in the other hand inhibiting empathy (socio-cognition). Effect of prenatal testosterone exposure also expressed in finger (2D:4D) digit ratio, resulting in male have smaller digit ratio than female. This research was aimed to investigate differences between sexes in socio-cognitive ability, digit ratio and their relationship among IPB University Students. Consistent with previous studies, male achieved lower score than female in cognitive empathy task (Reading the Mind in the Eyes test), with average correct answer 19.83 and 21.33 respectively. However no significant difference between sexes on self-report on empathy (Fisher Temperamental Inventory) is found. In case of digit ratio, the average digit ratio of male participant is 0.963 while female is 0.981. Even though the result shows decrement of socio-cognitive ability parallels to decrement of digit ratio, no statistical correlation is found between these parameters.
Keyword: empathy, prenatal testosterone, digit ratio

Judul: Correlation between Digit Ratio (2D:4D) and Physical Profile Factors on Hand Grip Strength (HGS) in College Students at IPB University
Abstrak: Digit ratio 2D:4D merupakan biomarker yang digunakan untuk melihat suatu karakter melalui gen yang ekspresinya dipengaruhi oleh jenis kelamin. Digit rasio seringkali dihubungkan dengan kekuatan genggaman. Penelitian sebelumnya menunjukkan korelasi antara digit ratio dengan kekuatan genggaman tangan pada laki-laki, sedangkan belum banyak dilakukan pada perempuan. Penelitian ini bertujuan menguji korelasi antara digit rasio dengan kekuatan genggaman tangan pada perempuan dewasa. Penelitian ini telah dilaksanakan pada bulan November 2023, dengan 250 partisipan mahasiswi di IPB University pada rentang usia 17-25 tahun. Jangka sorong digunakan untuk mengukur rasio digit (2D:4D) dan Hand grip-D Device akan digunakan untuk mengukur kekuatan genggaman tangan. Data dianalisis dengan perangkat lunak R studio. Korelasi antara digit rasio (2D:4D), kekuatan genggaman tanagn, dan faktor profil fisik dianalisis dengan uji korelasi spearman. Studi ini menunjukkan bahwa digit rasio mahasiswi di IPB University memiliki rata-rata rasio (=1) untuk kedua tangan. Digit rasio 2D:4D tidak memiliki hubungan yang signifikan dengan kekuatan genggaman tangan (kanan: p= - 0.00039, p-value= 0.95; kiri: p= 0.0217, p-value= 0.73). faktor lain yang diamati, seperti berat badan, tinggi badan, dan BMI menunjukkan korelasi yang signifikan dengan kekuatan denggaman tangan. Kata kunci : Biomarker, digit rasio 2D:4D, kekuatan genggaman tangan, korelasi, perempuan, Digit ratio 2D:4D is a biomarker used to see a character through genes whose expression is influenced by gender. Digit ratio is often associated with grip strength. Previous studies have shown a correlation between digit ratio and hand grip strength in men, while not much has been done in women. This study aims to examine the correlation between digit ratio and hand grip strength in adult women. This study was conducted in November 2023, with 250 female participants at IPB University in the age range of 17-25 years. A caliper was used to measure digit ratio (2D:4D) and Hand grip-D Device will be used to measure hand grip strength. Data were analyzed with R studio software. Correlations between digit ratio (2D:4D), hand grip strength, and physical profile factors were analyzed by Spearman correlation test. This study shows that digit ratio students at IPB University have an average ratio (=1) for both hands. Digit ratio 2D:4D had no significant relationship with hand grip strength (right: p= -0.00039, p-value = 0.95; left: p= 0.0217, p-value = 0.73). Other observed factors, such as weight, height, and BMI showed significant correlation with hand grip strength. Keywords: Biomarkers, 2D:4D digit ratio, handgrip strength, correlation, female
Keyword: biomarker, correlation, 2D:4D digit ratio, handgrip strength, female

Judul: Sintesis Flavonol melalui 2’-Hidroksikalkon
Abstrak: Flavonol is a class of flavonoids commonly found in fruits and vegetables. Flavonol is very useful, especially in food sector and health. In this study, flavonol unsubstituted was successfully synthesized from an intermediate material 2’-hydroxychalcone. The 2’-hydroxychalcone was synthesized by Claisen-Schmidt condensation method between o-hydroxyacetophenone and benzaldehyde using 4 different catalysts, namely KOH 60%, solid pellet of KOH-grinding technique, BF3-Et2O, and NaH in DMF. The KOH 60% was the best catalyst, giving the highest yield (57%). Afterward, the flavonol was synthesized in 1-stage oxidation cyclization of o-hydroxyacetophenone using Algar-Flynn-Oyamada (AFO) reaction, giving 76%. The flavonol total yield from 2’-hydroxychalcone was 43%. All synthesized products were characterized by their melting points and their spectra. The success of the synthesis flavonol opens the way to synthesis of useful flavonol derivatives such as quercetin and kaempferol.
Keyword: