Judul: Audit proses produksi roti manis isi di PT Nippon Indosari Corpindo Tbk. Cikarang, Bekasi
Abstrak: Nippon Indosari Corpindo Co. Ltd. is a company engaged in the manufacturing industry produced bread "Sari Roti". To maintain the quality of bakery products in order to remain in accordance with quality standards set by the company, needed a quality system process of production that work well. The purpose of this study are to identify the factors that caused deviations of quality sweet bread products by conducting an audit approach and advise the company in product quality improvement through the improvement of production processes. Data collection and processing acquired by using the seven tools quality control, including: check sheet, stratification, Pareto diagram, and cause and effect diagram. As results of observations, there are seven types of defects found in the sweet bread production process, such as dents (37%), bubbles (7%), burning (2%), leaking (5%), shape (13%), attached (15%), and others (20%). Quality improvement priorities is carried out on the kind of dent quality deviations on sweet bread. Dents on the sweet bread caused by the equipment used still manually and limited, side of conveyor pressing the edges of bread; operators who are less skilled, uncareful, and fatigue when putting bread into the conveyor; depanning methods are not effective and work instructions/SOP is less to explain about the procedure of putting the bread properly. Trial improvements designed to improve the system of production processes currently running. As a result, the trial was able to reduce the amount of dents on the sweet bread of 69.79%.
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Judul: Analisis Keseimbangan Lini dalam Proses Produksi Roti Tawar di PT Nippon Indosari Corpindo – Cikarang
Abstrak: The high growth rate in particular industries based on agriculture is followed by the development of increasingly advanced technology, will lead into a global competition and the existing problems in industries become more complex. In facing these industrialized world problems and global competition, accurately efficiency, effectiveness, and productivity are the key factors to be able to compete competitively for each agro-based industry. One of the effort that can be done to support is with some planning and designing of appropriately production systems with a continue production line balancing that influenced by operator performance, properly layout, and also the production queuing. The purpose of this research was to determine the standard working time on a number of work components that be involved in the process of white bread production, to analyze the layout, and to analyze the performance of queuing system in white bread production line that already exist. Working time measurement used to determine the standard working time by using the Westinghouse method in determining the value of adjustments and looseness. The layout analysis was analyzed by determining the level of activity relationship, total closeness rating, and activity relationship chart. Queuing analysis was done by forming a model that consisted of two types, namely material flow balancing analysis and Monte Carlo queuing simulation technique. Monte Carlo simulation technique used to obtain entity in the form of customer analysis, server analysis, and queue analysis, which are customer analysis consisted of number of finished, average waiting time (Wq), and average cycle time (W); server analysis consisted of server utilization; and queue analysis consisted of average queue length (Lq), and average waiting time (Wq). Production process in PT Nippon Indosari Corpindo was done by involving the cooperation between machines and operators which was deterministic and probabilistic. Work measurement was useful in determining the standard working time, layout analysis and queuing analysis. Time measurement was done by using the stopwatch method to the operator to determine the standard time, where the standard time that obtained from the calculation is in the amount of 8.45 hours for 1 batch (443.5 kg) of bread dough production. White bread production line at the PT Nippon Indosari Corpindo had a product layout which adjusted by its production process with have a straight line shape workmanship. Based on the analysis using the Analysis Relationship Chart, the formation changing in Raw Material and Mixing Department was needed. Its changing be based on sequence of work flow; efficiency of distance, time, and work; temperature, noise; level of comfort; ease of surveillance; and the existing of communication / work control paper. The highest value of Total Closeness Rating was Packing department (176), followed by Crating (168), Mixing (165), Oven (164), Raw Materials (92) and Finish Good department (87). The changing were made in the context of efficiency of time, distance, and packaging material transferring cost from Raw Material department onto Packing department which have a far distant. Queue analysis carried out by forming a queuing models which were divided into 9 queue model, they were Model A with a material flow balancing analysis at
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Judul: Mathematical model of Hematopoietic Stem Cell in Chronic Myelogenous Leukemia with and without Therapy
Abstrak: Leukemia or blood cancer is a diverse group of neoplastic disease, characterized by the multiplication of abnormal leukocytes or malignant transformation of blood-forming cells in bone marrow and lymphoid tissues. One of the most common types of leukemia is Chronic Myelogenous Leukemia (CML), which is usually diagnosed by the presence of certain chromosomal abnormalities, the so-called Philadelphia chromosome (Ph). One of the treatments of CML is Granulocyte Colony-Stimulating Factor (G-CSF). In this paper, we discuss two Hematopoietic Stem Cell (HSC) models, i.e. HSC without treatment and HSC with G-CSF treatment. The model of HSC without treatment included three equations representing the dynamics of HSC, leukocyte and platelet. Whereas, the model of HSC with G-CSF treatment includes the previous three equations and adds two more equations representing G-CSF injection and G-CSF circulation. The stability behavior of the system approaching the equilibrium points in the simulation study is carried out using Mathematica 7.0. The simulation results show that the G-CSF treatment can successfully decrease the number of HSC, which means reducing the CML.
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