Judul: Kajian Penerapan Metode Permukaan Respon Pada Formula Jamu Antidiabetes Dengan Ikan Zebra (Danio Rerio) Sebagai Hewan Uji
Abstrak: Jamu adalah obat tradisional terbuat dari bahan alami tumbuhan berkhasiat. Jamu yang baik adalah jamu yang memiliki komposisi pas. Secara statistik komposisi ini dapat ditentukan dengan mencari titik optimum yang diperoleh menggunakan metode permukaan respon (MPR). Penelitian ini bertujuan mencari titik optimum menggunakan MPR pada kombinasi formula jamu antidiabetes. Formula ini terdiri atas 4 peubah bebas tanaman yaitu sembung (X1), pare (X2), rimpang jahe (X3), dan bratawali (X4) serta satu peubah respon (Y) yaitu rata-rata selisih penurunan kadar gula darah ikan zebra. Perhitungan awal untuk mendapatkan model orde pertama menggunakan tiga peubah bebas X1, X2, dan X3. Model ini merepresentasikan hubungan antara peubah X dan peubah Y yang berbentuk linier. Model orde kedua selanjutnya ditentukan dan diuji kelayakan modelnya. Berdasarkan model orde kedua yang layak dengan nilai R-Square 74%, diperoleh titik optimum berada pada kombinasi X1 sebesar 8.08%, X2 sebesar 7.51%, X3 sebesar 34.15%, dan X4 sebesar 50.26%. Titik optimum X4 merupakan sisa proporsi dari ketiga titik optimum X1, X2, dan X3.
Keyword: antidiabetes, formula jamu, metode permukaan respon, titik optimum

Judul: Pendekatan Bioinformatika Formulasi Jamu Baru Berkhasiat Antidiabetes dengan Ikan Zebra (Danio rerio) sebagai Hewan Model
Abstrak: Jamu composition was formulated without any provision like Traditional Chinese Medicine. Recent studies showed regularity pattern through statistical database. Jamu formulations in this study were made using Design Expert and its efficacy predicted using models partial least square discriminant analysis (PLSDA), coefficient PLSDA multiways, and Support Vector Machine. The prediction indicated that 4 plants used were sembung, pare, ginger, and bratawali. The efficacy was verified using zebrafish (D. rerio) as an animal test. Hyperglycemia in the fish was induced by soaking them in alloxan 0.1% for 10 min, glucose 1% for 10 min, and distilled water for 60 min in sequence. One-way t test showed that the increasing blood sugar levels was not significant (p>0.05). These results confirm that the induction process have not been successful to increase the average blood sugar levels. Application of jamu into the fish was done for 3 days after the induction. Statistical observation for all compositions of jamu showed that group 1 has the greatest decline difference.
Keyword: zebrafish, jamu, bioinformatic of jamu, antidiabetic

Judul: Analisis dan Implementasi Certificate Authorities (CA) pada Public Switched Telephone Network (PSTN)
Abstrak: Secure Telephone Protocol has ability to authenticate involved party and keep the secrecy of the message sent over the protocol. The secrecy of the message archieved by using symmetric key cryptographic scheme, and authentication archieved using public key cryptographic scheme. One of several party involved in the protocol and hold an important function called Certificate Authorities or CA. CA responsible for generating public key pair for other party involved in the protocol. When CA generates public key pair, several primitive cryptographic scheme used for guarantee the security of the key. Two of them are hash function SHA-1 and El-Gamal public key scheme embedded in Digital Signature Algorithm scheme. The prototype implementing the scheme above developed using Java programming language with JCE addition from Bauncy Castle. The analysis towards implemented prototype indicates that the prototype still has some flaws to be implemented in real world.
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