Judul: Strategi Pengembangan Usaha Brownies Singkong pada Mr.BrownCo Kabupaten Bogor
Abstrak: This research was held on September 2012 until May 2013. The research aims to identify working condition of Mr.BrownCo in Bogor city by analyzing overall variables that have been identified. Formulating alternative strategy that is appropriate to apply in the development of the work. Respondent determination was done on internal party for two persons, the external party for one person, and ten consumers. Data analysis that has been used in this research are: IE analysis, SWOT, and OSPM. The analysis result shows Mr.BrownCo is in the stage of Grow and Developing. The Strategy that should be done to develop the business by strategy prioritizing is to open Mr.BrownCo new branches in out of Bogor city, doing promotion by using technology that is available (online marketing), also taking part in bazaar activities or exhibitions and cooperate with radio and television ,locally or nationally to introduce the products of Mr.BrownCo. Increasing consumer loyalty by keeping and enhancing products qualities, also always making new innovation, make or offering affordable package, and to give free internet (wifi) facility for the customers.
Keyword: QSPM, SWOT, Strategy

Judul: Optimalisasi Produksi Brownies Singkong pada Mr.BrownCo Bogor
Abstrak: Bogor city is one area that experiencing rapid development of UMKM . Mr.BrownCo is one of UMKM in Bogor that capture business opportunities with compared unique food product to other food business . Brownies Cassava is one kind of snack practical with excellent nutritional content and safe for consumption so make such products can provide value added to the company in addition to excellence in product diversification of raw materials . One of the goals to be achieved by the company is the optimal profit . To achieve the optimization of the profits of a company faced with the reality of limited resources. Optimal production plan obtained by using linear programming . The output of data processing by using LINDO will provide an optimal combination of products so that maximum benefit can be achieved . The output of the data processing that provide an optimal combination will be compared with the actual conditions that occur in the company and to evaluate whether the activities undertaken during this production is optimal or not . Based on the results of the optimization analysis can be seen that the rate of production of brownies in mr.BrownCo during August - November 2012 have not been optimal . This is because there are differences between the actual conditions with optimal conditions . Mr.BrownCo should produce up to optimal conditions in order to make a profit ( gross profit ) is maximum . Mr.BrownCo should set back the excess availability of resources such as raw materials , labor hours and machine hours.
Keyword: Linier Programming, Optimization, Cassava Brownies

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
Keyword: