Judul: Deteksi Secara Imunohistokimia Imunoglobulin A (IgA) pada Usus Halus Tikus yang Diberi Bakteri Asam Laktat (BAL) dan Enteropatogenik Escherichia coli (EPEC)
Abstrak: This study was conducted to evaluate the effect of Lactobacillus plantarum and Lactobacillus fermentum on the immunohistochemical profile of immunoglobulin A (IgA) and the intestinal mucosa thickness of Enteropathogenic E. coli (EPEC) treated rats. A total of 90 male Sparague Dawley rats were used in this study. They were divided into 6 groups: (1) negative control treated group, (2) Lactobacillus plantarum treated group, (3) Lactobacillus fermentum treated group, (4) Lactobacillus plantarum and EPEC treated group, (5) Lactobacillus fermentum and EPEC treated group, and (6) EPEC treated (positive control) group. The results showed that both Lactobacillus fermentum and Lactobacillus plantarum treatment for 2 to 3 weeks increased the thickness of rat’s mucosal small intestine. In the EPEC treated rats, either Lactobacillus fermentum and Lactobacillus plantarum treatment for 2 weeks increased the thickness of rat’s mucosal small intestine. Lactobacillus fermentum treatment for 2 weeks increased the content of IgA in rat’s mucosal small intestine at both conditions; with and without EPEC treatment. Lactobacillus plantarum treatment for 2 weeks only increased the content of IgA in rat’s duodenum and jejunum, while in the EPEC treated rats, Lactobacillus plantarum treatment for 2 weeks could maintained the content of IgA in rat’s mucosal small intestine. Lactobacillus fermentum gave better effect than Lactobacillus plantarum on increasing the content of IgA in rat’s small intestine
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Judul: Efek probiotik indigenus pada profil imunohistokimia antioksidan superoksida dismutase (SOD) di hati tikus yang dipapar enteropathogenic Escherichia coli (EPEC)
Abstrak: The study was conducted to analyze influence of indigeneous probiotic Lactobacillus plantarum and Lactobacillus fermentum on immunohistochemical profile of antioxidant superoxide dismutase (SOD) in liver of enteropathogenic Escherichia coli (EPEC) treated rats. A total of 90 male rats (Sprague Dawley) were divided into six groups; (A) negative control, (B) Lactobacillus plantarum treated group, (C) Lactobacillus fermentum treated group, (D) Lactobacillus plantarum and EPEC treated group, (E) Lactobacillus fermentum and EPEC treated group, and (F) EPEC treated group (positive control). The content of antioxidant copper, zinc-superoxide dismutase (Cu,Zn-SOD) was analyzed with immunohistochemical techniques using monoclonal antibody of Cu,Zn-SOD. The result showed that L. fermentum increased the content of Cu,Zn-SOD in rat liver on 2nd and 3rd weeks at both conditions; with and without EPEC treatment. L. plantarum treatment for 1 week until 3 weeks, could maintain the content of Cu,Zn-SOD in rat liver tissue as well as negative control. While, in L. plantarum and EPEC treated group, the content of Cu,Zn-SOD decreased after one week of EPEC treatment. L. fermentum showed better effect in terms increase the content of Cu,Zn-SOD in rat liver tissue.
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Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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