Judul: Hubungan Unsur Iklim dengan Titik Panas (Hotspot) di Kabupaten Ogan Komering Ilir, Propinsi Sumatera Selatan Periode Tahun 2001-2002
Abstrak: Bencana kebakaran hutan menimbulkan kerugian yang sangat besar baik dari segi ekonomi maupun ekologi. Kebakaran hutan disebabkan oleh faktor manusia dan faktor alam. Faktor manusia, biasanya disebabkan oleh kegiatan pembukaan/penyiapan lahan oleh petani, HPH (Hak Pengusahaan Hutan), HTI (Hutan Tanaman Industri), dan Perkebunan sedangkan faktor alam biasanya disebabkan oleh petir, letusan gunung berapi dan iklim seperti suhu, kelembaban, curah hujan dan angin. Dimana unsur iklim tersebut mempengaruhi ketersediaan oksigen, ketersediaan bahan bakar, dan penjalaran api.
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Judul: Studi Tentang Sebaran Titik Panas (Hotspot) Bulanan Sebagai Penduga Terjadinya Kebakaran Hutan dan Lahan di Propinsi Sumatera Selatan Tahun 2001 dan 2002
Abstrak: Bencana kebakaran hutan menimbulkan kerugian yang besar baik dari segi ekonomi maupun ekologi. Kebakaran hutan yang terjadi pada tahun 1982/1983, 1994 dan tahun 1997/1998 kembali terulang pada tahun 1999, 2000, 200I dan 2002. Diperlukan manajemen yang terpadu dan terarah agar kebakaran hutan dapat dikendalikan. Metode untuk mendukung kegiatan ini dapat berupa analisa keberadaan titik panas (hot spot). Titik panas dapat dideteksi dengan satelit NOAA (National Oceanic and Atmosperic Administration), yang dilengkapi sensor A VHRR (Advanced Very High Resolution Radiometer).
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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