Judul: Studi Toksikopatologi Organ Hati dan Ginjal Mencit (Mus musculus) Akibat Pemberian Berbagai Fraksi Pauh Kijang (Irvingia malayana Oliv. Ex A. Benn).
Abstrak: The aim of this research was to examine the toxicopathology effect from various fractions of Irvingia malayana Oliv. Ex A. Benn on mice liver and kidney. Twenty five male mice age ±3 months with ±30 grams BW used in this research were divided into five group of treatments. Each mice from four groups of treatment was received 100 mg/kg BW fractions of I. malayana from chloroform solvent, ethyl acetate solvent, hexane solvent, and ethanol residue solvent, while one group control received carboxymethocellulose. After receiving 100 mg/kg BW fraction I. malayana for seven days, the mice then were sacrificed, the liver and kidney were sampled and fixed in Buffer Neutral Formalin 10% solution to make histopathology slides with Haematoxylin and Eosin stain. The histopathology slides were observed under light microscope. The lesion observed in the liver and kidney proximal tubular epithelium was degeneration and necrosis/apoptotic. The result from this research indicated that the dose of 100 mg/kg BW fraction of I. malayana from various solvent were not toxic to hepatocytes and proximal tubular epithelium.
Keyword: 

Judul: Pemeriksaan Toksikopatologi Efek Pemberian Berbagai Fraksinasi Ekstrak Batang Gatep Pahit (Quassia indica (Gaernt.) Nooteboom) Pada Organ Hati dan Ginjal Mencit (Mus musculus)
Abstrak: The aim of this research was to study the toxicopathology effect of gatep pahit (Q. indica) stem extract fractionation given using various solvents of different polarity (hexane, chloroform, ethyl acetate, and ethanol residue) on mice (Mus musculus) liver and kidney. Twenty five mice (Mus musculus) were divided into five groups. Four groups were given 100 mg/kg BW stem extract fractionation of Q. indica using various different solvent and one group of mice performed as control which received carboxymethocellulose (CMC-Na) 1%. After 1 week of treatment, the mice then were euthanized with over dose of ether. The liver and kidney were taken and fixed in 10% of Buffer Neutral Formalin for 48 hours. The tissue samples were processed to make histopathology slides stained with Hematoxylin Eosin. The tissues were examined under the light microscope. The toxicopathology assay included to count the cells under went necrosis/apoptosis and degeneration. The results revealed that the Q. indica chloroform fraction has the lowest level of damage to hepatocytes while hexane fraction showed the most hepatocytes damaged. The Q. indica hexane fraction caused the less damage in kidney tubular epithelium while the ethyl acetate showed the most epithelium damaged.
Keyword: 

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
Keyword: