Judul: Minat Beli dan Willingness To Pay Generasi Milenial dan Generasi Z Kota Bandar Lampung Terhadap Kosmetik Halal Merek Lokal.
Abstrak: Besarnya pangsa pasar kosmetik di Indonesia saat ini belum sepenuhnya diiringi dengan kesadaran yang tinggi dari konsumen dan produsen kosmetik lokal akan pentingnya label halal terlihat dari sertifikasi halal yang belum didapatkan oleh seluruh produk kosmetik lokal yang beredar. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi minat beli dan willingness to pay Generasi Milenial (Generasi Y) dan Generasi Z Kota Bandar Lampung terhadap kosmetik halal lokal dengan menggunakan metode SEM-PLS untuk menganalisis pengaruh setiap variabelnya dan CVM untuk menganalisis jumlah tambahan biaya yang rela dikeluarkan untuk mendapatkan kosmetik merek lokal yang berlabel halal. Hasil penelitian menemukan bahwa citra merek dan religiusitas berpengaruh positif dan signifikan pada willingness to pay, baik secara langsung maupun tidak langsung dengan mediasi melalui minat beli terlebih dahulu sebagai variabel intervening. Minat beli sendiri berpengaruh positif dan signifikan terhadap Willingness to pay. Berdasarkan hasil analisis CVM besaran tambahan biaya yang rela dibayarkan untuk mendapatkan kosmetik lokal yang berlabel halal adalah sebesar Rp23.280,00., The large cosmetic market share in Indonesia has not been fully accompanied by high awareness from consumers and local cosmetic manufacturers about the importance of halal labels that’s showed by the halal certification which has not been obtained thoroughly by local cosmetic products. This study aims to analyze the factors that influence purchase intention and willingness to pay Millenial Generation and Gen Z in Bandar Lampung for halal-labeled local brand cosmetics by using the SEM-PLS method to determine the effect of each variable and CVM to determine the amount of additional costs that are willing to be paid to get local brand cosmetics that are halal-labeled. The result of the study found that brand image and religiousity significantly affect willingness to pay both directly and through purchase intention as intervening variable. Purchase intention itself positively-significant affects willingness to pay. Based on CVM result shows additional price that customers willing to pay is Rp23.280,00.
Keyword: minat beli, willingness to pay, Local halal-labeled cosmetics, purchase intention

Judul: MILLENNIAL GENERATION WILLINGNESS TO PAY IN BOGOR REGENCY FOR HALAL COSMETICS
Abstrak: Konsumsi global muslim akan kosmetik saat ini meningkat, bahkan Indonesia menempati posisi kedua pada tahun 2020 sebagai konsumen kosmetik halal global. Akan tetapi, hanya 9,6 persen produk telah tersertifikasi, sedangkan sisanya belum memiliki sertifikat halal. Tujuan penelitian ini adalah mengidentifikasi karakteristik generasi milenial di Kabupaten Bogor terhadap kosmetik bersertifikat halal, menghitung besarnya willingness to pay (WTP) generasi milenial terhadap biaya tambahan sertifikasi halal pada kosmetik, dan menganalisis faktor-faktor yang mempengaruhi WTP generasi milenial terhadap kosmetik bersertifikat halal. Metode penarikan sampel yang digunakan adalah purposive sampling dengan dianalisis menggunakan Structural Equation Model-Partial Least Square (SEM-PLS), dan Contingent Valuation Model (CVM). Hasil penelitian menunjukkan bahwa faktor yang signifikan adalah label halal dan customer perceived value. Sedangkan nilai WTP yang diperoleh untuk kosmetik halal adalah sebesar Rp25.700,00, Muslim global consumption of cosmetics is currently increasing, even Indonesia occupies the second position in 2020 as a global consumer of halal cosmetics. However, only 9,6 percent of the products have been certified, while the rest do not yet have a halal certificate. The purpose of this study is to identify consumer characteristics of the millennial generation in Bogor Regency towards halal-certified cosmetics, calculate the millennial generation's willingness to pay (WTP) for additional costs of halal certification in cosmetics, and analyze the factors that influence the millennial generation's WTP towards halal-certified cosmetics. The sampling method used is purposive sampling and analyzed using Structural Equation Model-Partial Least Square (SEM-PLS) and Contingent Valuation Model (CVM). The results showed that the significant factors are the halal label and customer perceived value. While the WTP value obtained for halal cosmetics is Rp25,700,000
Keyword: contingent valuation method, halal cosmetics, millennial generation, structural equation model, willingness to pay

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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