Judul: Keragaman Gen TP53INP1 dan Asosiasinya dengan Komposisi Asam Lemak Daging Domba
Abstrak: Gen TP53INP1 adalah salah satu gen yang terlibat dalam pengaturan metabolisme lemak dan memiliki keterkaitan dengan komposisi asam lemak pada domba. Penelitian ini bertujuan mengindentifikasi keragaman gen TP53INP1 dan asosiasinya dengan komposisi asam lemak daging domba lokal Indonesia. Total sampel yang digunakan sebanyak 130 sampel DNA ekor domba jantan yang terdiri dari 10 ekor domba barbados cross (DBC), 10 ekor domba compass agrinak (DCA), 20 ekor domba ekor gemuk (DEG), 53 ekor domba ekor tipis (DET), 10 ekor domba komposit garut (DKG), dan 27 ekor domba jonggol (DJG). Identifikasi keragaman gen TP53INP1|NlAIII menggunakan metode Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Ukuran produk PCR yang teramplifikasi memiliki panjang basa sebesar 457 bp. Keragaman gen TP53INP1 ditemukan pada semua jenis sampel domba dengan genotipe AA, AG, dan GG. Frekuensi alel TP53INP1|NlAIII berada dalam keseimbangan Hardy-Weinberg kecuali pada domba ekor tipis (DET). Asosisiasi SNP gen TP53INP1 dengan asam lemak menggunakan uji T (P<0,05) pada domba yaitu asam palmitat (C16:0), asam behenat (C22:0), asam lignoserat (C24:0), asam palmitoleat (C16:1), asam elaidat (C18:1n9t), asam gondoat (C20:1), asam nervonat (C24:1), asam oleat (C18:1n9c), dan asam linolelaidat (C18:2n9t). Disimpulkan bahwa SNP gen TP53INP1 mempengaruhi komposisi asam lemak domba., TP53INP1 gene is one of the genes involved in regulating lipid metabolism and is related to the fatty acid composition of sheep. This study aims to identify the diversity of TP53INP1 gene and it’s association with the fatty acid composition of Indonesian local sheeps. The total sample used was 130 ram DNA samples consisting of 10 barbados cross (DBC), 10 agrinak compass sheep (DCA), 20 javanese fat tailed (DEG), 53 javanese thin tailed (DET), 10 garut composite sheep (DKG), and 27 jonggol sheep (DJG). Identification of the diversity of TP53INP1|NlAIII was identified by the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) method. The amplified PCR product had 457 bp. The diversity of the TP53INP1 gene was found in all types of sheep samples with the genotypes AA, AG, and GG. The allele frequency was in Hardy-Weinberg equilibrium except for the thin tailed sheep (DET). SNP TP53INP1 gene used the T test was associated (P<0,05) with fatty acids in sheeps, such as palmitic acid (C16:0), behenic acid (C22:0), lignoceric acid (C24:0), palmitoleic acid (C16:1), elaidic acid ( C18:1n9t), gondoic acid (C20:1), nervonic acid (C24:1), oleic acid (C18:1n9c), and linolelaidic acid (C18:2n9t). It could be concluded that the SNP TP53INP1 gene effects to the fatty acid composition of lamb.
Keyword: TP53INP1 gene, fatty acids, PCR-RFLP, sheep

Judul: Keragaman Titik Mutasi g.8539 C>T Gen DGAT1 terhadap Karakteristik Karkas dan Asam Lemak Domba.
Abstrak: Diacylglycerol Acyltransferasel 1 (DGAT1) merupakan gen yang berperan penting dalam regulasi karkas dan asam lemak domba. Penelitian ini bertujuan mengidentifikasi keragaman dan asosiasi DGAT1 dengan karakteristik karkas dan asam lemak pada domba lokal Indonesia. Total sampel yang digunakan sebanyak 150 yang terdiri atas 35 domba compass agrinak (DCA), 36 domba barbados cross (DBC), 41 domba komposit garut (DKG), 20 domba ekor gemuk (DEG), dan 18 domba ekor tipis (DET). Identifikasi keragaman DGAT1|AluI dianalisis menggunakan Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Ukuran produk amplifikasi adalah 466 bp. Keragaman gen DGAT1 ditemukan dalam DET dan DEG, sedangkan DCA, DBC, dan DKG bersifat monomorfik. Genotipe CC dan CT ditemukan dalam DET dan DEG. SNP gen DGAT1 berasosiasi (P<0.05) dengan karakteristik karkas, yaitu bobot dan panjang karkas. Keragaman DGAT1 juga berasosiasi (P<0.05) dengan asam lemak jenuh, yaitu asam stearat (C18:0) dan asam arakidat (C20:0) dan asam lemak tak jenuh tunggal, yaitu asam oleat (C18:1n9c). SNP gen DGAT1 disimpulkan memiliki kontribusi dalam karakteristik karkas dan komposisi asam lemak domba.
Keyword: asam lemak, domba, gen DGAT1, karakteristik karkas, PCR-RFLP

Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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