Judul: Aktivitas antijerawat formula campuran temu lawak dan meniran serta penentuan sidik jari kromatografinya
Abstrak: Anti-acne activity of extracts from C. xanthorriza and P. niruri has been analyzed through antioxidant and antibacterial activity assays. Extraction process was conducted by two different maceration methods, Indonesian and traditional chinese medicine (TCM) with ethanol 96% as the solvent. Formula 6 (2/3 C. xanthorriza:1/6 P. niruri:1/6 starch) was the most active anti-acne formula with IC50 of antioxidant values of 93.17 ppm, the minimum inhibitory concentration against Staphylococcus epidermidis was 0.25 mg/mL, and the minimum bactericidal concentration was 0.50 mg/mL. Moreover, TCM maceration was better than the Indonesian method in terms of antioxidant and antibacterial activities. Fingerprint analysis of formula was undertaken using thin layer chromatography. The optimum mobile phase was chloroform that gave 9 bands. Further, the (HPLC) analysis with C18 as column and gradient of acetonitrile and water as the mobile phase showed that the peak area of phyllanthin and curcumin increased when the standard compounds were added into the sample.
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Judul: Aktivitas antijerawat formula campuran meniran dan temu lawak serta aktivitas inhibisinya terhadap katalase Staphylococcus aureus
Abstrak: Acne is an inflammation of skin caused by Staphylococcus aureus, S. epidermidis, and Propionibacterium acnes bacteria. Antiacne activity of temu lawak and meniran has been analyzed through antibacterial activities against S. aureus and S. epidermidis and inhibition of S. aureus catalase activity. Temu lawak and meniran were extracted by using maceration technique in 96% ethanol with two different maceration methods, Indonesian and traditional chinese medicine. S. aureus and S. epidermidis were successfully isolated. The growth of S. aureus was inhibited by temu lawak extract with minimum bactericidal concentration (MBC) 150 ppm and inhibition zone index 0.38. The growth of S. epidermidis was inhibited by mixture of temu lawak 2/3 and meniran 1/6 with MBC 300 ppm and inhibition zone index 0.40. Thin layer chromatography profile of both extracts showed curcuminoid band. Catalase enzyme was successfully isolated from S. aureus. Mixture of temulawak 2/3 and meniran 1/6 gave the best catalase inhibition activity, 6.88% in 500 ppm formula concentration.
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Judul: Karakteristik Anatomi Skelet Kepala Buaya senyulong (Tomistoma schlegelii).
Abstrak: Buaya sepit atau senyulong (Tomistoma schlegelii) merupakan jenis buaya asli Indonesia yang berhabitat di sungai-sungai Sumatera, Kalimantan, dan juga pedalaman Sulawesi. Salah satu ciri khas buaya senyulong adalah bentuk moncong yang runcing dan sempit, namun hingga saat ini informasi mengenai struktur skelet kepala buaya senyulong sangat terbatas. Penelitian ini bertujuan untuk mempelajari karakteristik anatomi skelet kepala buaya senyulong yang dikatikan dengan fungsi dan perilakunya. Penelitian dilakukan secara eksploratif dengan melakukan pengamatan, pencatatan, dan pengambilan gambar dari skelet kepala buaya senyulong. Skelet kepala berukuran panjang 70 cm, lebar 29 cm, dan tingggi 17 cm dengan permukaan kasar pada os nasale, os frontale, os maxilla, os mandibula, os lacrimale, os jugale. Jumlah gigi pada buaya ini sebanyak 78 buah, terdiri dari 4 buah gigi premaxila, 16 buah gigi maxila, dan 19 buah gigi mandibula. Pada regio orbitalis ditemukan dua pasang fenestrae temporales yang berkembang baik. Fenestra supratemporale merupakan lubang oval yang membentang di sepanjang os parietale. Fenestra infratemporale berbentuk segitiga dan dibatasi oleh os squamosum, os postorbitale, os jugulare, dan os quadratum. Os mandibula hewan ini mempunyai symphysis mandibularis yang panjang yaitu garis yang melintang di corpus mandibulae. Secara fungsional ukuran symphysis mandibularis berkaitan dengan adaptasi hewan terhadap diet makan.
Keyword: kepala, moncong, Tomistoma schlegelii