Judul: Pengaruh enzim pepsin dan tripsin terhadap titer IgG anti H5N1 dari kolostrum sapi yang divaksin H5N1
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh paparan enzim pepsin dan tripsin terhadap titer IgG anti H5N1 dalam kolostrum. Tiga buah sampel kolostrum berasal dari 2 ekor induk sapi yang telah divaksin H5N1 pada masa kebuntingan trimester akhir. Pengujian titer antibodi dilakukan melalui pemaparan enzim pepsin dan tripsin, masing-masing pada masa inkubasi 30 dan 60 menit. Deteksi antibodi dilakukan dengan uji hemaglutinasi inhibisi (HI). Hasil uji HI terhadap kolostrum menunjukkan adanya penurunan titer antibodi akibat pemaparan enzim pepsin dan trispin. Semua sampel kolostrum yang direaksikan dengan enzim tripsin, mengalami penurunan titer antibodi hingga 20 (2 log 0) baik pada masa inkubasi 30 maupun 60 menit. Sementara itu, sampel kolostrum yang direaksikan dengan enzim pepsin juga menunjukkan penurunan titer antibodi hingga 23 pada masa inkubasi 30 menit dan 22 pada masa inkubasi 60 menit. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa IgG akan mengalami penurunan titer akibat aktivitas enzim pepsin dan tripsin yang merupakan enzim proteolitik dalam saluran pencernaan manusia.
Keyword: IgG, Pepsin, Trypsin, Colostrums, Bogor Agricultural University

Judul: Pengaruh Ph Terhadap IgG Anti H5N1 Asal Kolostrum Sapi Yang Divaksin Dengan Vaksin Avian Influenza H5N1
Abstrak: The aims of this study is to determine the stability of IgG anti-H5 from bovine colostrum (BC) after exposure to acid and basic pH. Two samples of BC, whole colostrum and whey colostrum incubated at pH 4, 5, 9, and 10 for 30 and 60 minutes. Haemagglutination Inhibition (HI) test is used to determine IgG titer after incubation. IgG titers decreased after exposure to acid or basic pH. Acid exposure (pH 5) decreased antibodi titer of whole colostrum as much as 3,75% and 16,25% after incubation 30 and 60 minutes respectively. Antibody titer to pH 4 also decreased until 12,5% and 16,5% after for 30 and 60 minutes respectively. In whey colostrum, both pH 4 and pH 5 reduce 18,75% antibody titer. On other hand, IgG titers is decreased until 100% at basic pH (pH 9-10). In conclusion, IgG from BC is degraded in acidic and alkaline conditions.
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Judul: Tinjauan Matematis pada Model Makroskopik dan Mikroskopik Arus Lalu-lintas
Abstrak: Traffic flow phenomenon can be described through mathematical model such as continuous dynamic model with an ordinary differential equation so that it can be solved with integral factors. In this paper three simple models of traffic flow are discussed, i.e, two macroscopic and one microscopic models. Macroscopic model formulates dynamics of the traffic flow that occurs on a large number of vehicles on a road. While the microscopic model explains drivers’ behavior in their interaction with other vehicles ahead, i.e, car-following model. This paper shows the existence of ordinary differential equation found in the traffic flow model and indicates some different representations in the context of the same model. It also reviews a simple model of traffic flow along a single link, which leads to some unexpected results, i.e, it can express the solution model in term of link outflows as well as trip time. In the microscopic model, simulation is done to illustrate the behavior of the drivers with a sensitivity coefficient as a benchmark parameter.
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