Judul: Perilaku disolusi nanokapsul ketoprofen tersalut gel kitosan-alginat  secara in vitro
Abstrak: Modified chitosan has been used as coating agent. Chitosan-alginate gel is potential to be applied as coating agent in drugs delivery system. Dissolution result indicates that chitosan-alginate membrane is the best in coating ketoprofen, but the microcapsule is still too big to be used. This study used 9 formula nanocapsule ketoprofen dissolution coated by chitosan-alginate gel. The Tween 80 solution concentrations used in the process were 1, 2, and 3% (v/v). The maximum ketoprofen releasing rate was observed at the addition of 2% Tween 80 solution. Four ketoprofen releasing mechanism were studied, i.e zero order release, first order release, Higuchi, Hixson-C, and Koremeyer-Peppas. The kinetic model in general follows Korsmeyer-Peppas model.
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Judul: Perilaku Disolusi Ketoprofen Tersalut Rangkap dalam Gel Kitosan-Gom Guar dengan Alginat.
Abstrak: Modification of chitosan gel by guar gum hydrocoloid with glutaraldehyde cross-link is capable to coat drug as microcapsule. The release rate in gastric medium and intestinal has been studied by dissolution test. Dissolution result of chitosan-gum guar coated ketoprofen previously showed that the microcapsule shaterred at gastric pH so that the drug release was not restrained. Double coating of ketoprofen by chitosan-gum guar with alginate in order to improve ketoprofen release has been done in this research. A number of concentration levels of alginate and CaCl2 solutions were applied for optimation of coat performance. Test dissolution result of ketoprofen showed time effect to ketoprofen release through kinetic models of drugs release. In acid medium, a large part of coating formulas followed Korsmeyer-Peppas model, while all coating formulas followed Korsmeyer-Peppas model in alkaline medium. The mechanism of drugs release in this research is diffusion.
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Judul: Ekologi merak hijau jawa (Pavo muticus muticus) Linnaeus 1758 pada beberapa tipe habitat di Ujung Timur Penyebarannya Jawa Timur, Indonesia
Abstrak: Merak hijau jawa merupakan salah satu jenis burung yang dilindungi.di Indonesia berdasarkan SK Mentan No 66/Kpts/Um/2/1973 dan Peraturan Pemerintah Republik Indonesia No 7 tahun 1999. Menurut ICBP (The International Council for Bird Preservation) merak hijau sebagai jenis burung yang tergolong terancam secara keseluruhan (globally threatened) baik populasi maupun habitatnya, sedangkan CITES mencantumkan merak hijau ke dalam Appendix II, merak hijau dari alam tidak bisa langsung diperdagangkan dan BirdLife International (2007) memasukkan golongan burung yang endangered. Tekanan terhadap populasi dan habitat merak hijau jawa sangat besar, sehingga kondisi populasinya menurun pada setiap penyebaran lokalnya, habitatnya terfragmentasi bahkan terisolasi. Tekanan terhadap populasi terutama karena perburuan liar. Namun demikian fakta menunjukan bahwa merak hijau jawa masih ada (exist), hal ini memberikan gambaran bahwa burung ini tentunya memiliki strategi ekologi tertentu untuk tetap bertahan hidup di alam pada berbagai tipe habitat.
Keyword: Pavo muticus muticus, Call count transect method, Pavo cristatus, Pavo muticus, Pavo muticus spicifer, Pavo muticus imperator, Pavo muticus muticus, Javan Green Peafowl, East Java