Judul: Pengembangan Sistem Penunjang Keputusan Seleksi Beastudi Etos Dompet Dhuafa Republika
Abstrak: Setelah hllus dari SO Sumbergirang II pada tahun 1992. penulis melanjutkan studi di SL TP Negeri I Lasem, Rembang. Tabun 1998 penulis tulus dari SMU Negeri I Rernbang dan pada tahun yang sarna penulis diterima sebagai mahasiswi di Departemen lImo Komputer Institut Pertanian Bogor melalui jalur USMI.
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Judul: Perbandingan sistem PMDK dan UMPTN terhadap lulusan IPB (Angkatan 21 1984/1985) bulan september 1988 sampai september 1989
Abstrak: Latar belakang penelitian ini adalah pentingnya sistem penyeleksian dalam memilih calon mahasiswa baru di PTN yang mempunyai kemampuan akademik, yang sangat berpengaruh lulusan yang dihasilkan. pada Tujuan penelitian ini adalah untuk membandingkan tingkat keberhasilan kedua sistem terhadap lulusan yang dihasilkan secara umum serta berdasarkan jenis kelamin dan daerah bagi asal SMA. Juga diharapkan dapat memberikan gambaran sistem penyeleksian selanjutnya dan kelancaran studi di IPB. Bahan penelitian diperoleh dari BAAK, Direktorat TPB dan semua Fakultas di IPB, terdiri atas jalur masuk, jenis kelamin, daerah asal SMA, fakultas, predikat di TPB dan lulusan. Metode yang digunakan adalah metode peluang Bayes yang menggunakan prinsip dasar definisi peluang bersyarat dan teorema peluang total. Agar lebih mudah melihatny, digambarkan dalam bentuk diagram pohon. ...
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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