Judul: Studi Faktor-Faktor Sosial Ekologi dalam Pengelolaan Ekosistem Mangrove Berbasis Masyarakat (Studi Kasus Desa Kartika Jaya dan Desa Wonosari Kecamatan Patebon, Kabupaten Kendal, Provinsi Jawa Tengah)
Abstrak: This study was conducted to determine the typology of mangrove and links between social conditions and community participation in mangrove ecosystem in the conservation area of Kartika Jaya and Wonosari village, District Patebon, Kendal. This research has been conducted with direct observation in the field and interviews with 30 persons in every village. The result from observation of ecological mangrove condition show that typology of mangrove in both area are dominated by Avicennia marina with good condition, mangrove density range is about 1067-1178 ind/ha and 1622-2000 ind/ha in accordance with the Decree of the State Minister for the Environment No. 201 Year 2004. Analysis of Principal Component Analysis (PCA) results that the social factors affecting the conservation in Kartika Jaya villages are community participation in mangrove planting, knowledge about the function of mangrove ecosystems, the distance to the ecosystem, and type of job. While the determined social factors in Desa Wonosari are community participation in mangrove planting as well, knowledge about functions and types of mangrove, the abrasion experience, and home distance.
Keyword: Bogor Agricultural University (IPB), society, ecology, social

Judul: Kajian Partisipasi Masyarakat Terhadap Pelestarian Hutan Mangrove (Studi Kasus: Desa Mambo Kecamatan Bone dan Desa Labulu-bulu Kecamatan Parigi Kabupaten Muna Provinsi Sulawesi Tenggara)
Abstrak: Tujuan penelitian: (1 ).mengetahui tingkat partisipasi masyarakat. (2 ).mengetahui faktor-faktor yang mempengaruhi partisipasi masyarakat (3) mengetahui strategi yang digunakan dalam pengembangan paritsipasi masyarakat di Desa Marobo dan Desa Labulu-bulu. Variabel-variabel yang diamati adalah: Faktor internal (umur, lama tinggal, jumlah anggota keluarga, pendidikan, dan pendapatan) Faktor eksternal (kelompok keterlibatan pemerintah, manfaat yang diperoleh dan pemahaman masyarakat terhadap ekosistem mangrove, dan tingkat partisipasi (perencanaan, penanaman, pemeliharaan dan pengawasan, penanaman atas kehendak sendiri) Untuk melihat faktor faktor yang berpengaruh dalam tingkat partisipasi digunakan analisis PCA, untuk melihat strategi yang digunakan dalam pengembangan partisipasi masyarakat menggunakan analisis SWOT. Jumlah responden Desa Marobo 61 orang dan Desa Labulu-bulu 51 orang. Tingkat partisipasi rnasyarakat Desa Marobo dipengaruhi oleh umur, lama tinggal, jumlah anggota keJuarga. Desa Labulu-bulu dipengaruhi oleh manfaat hutan mangrove, pendidikan formal, dan pendapatan rata-rata per bulan. Strategi pengembangan partisipasi masyarakat menurut skala prioritas : ( l ) menetapkan kawasan ini sebagai kawasan pengelolaan pesisir (mangrove) yang lestari dan berkelanjutan,(2)meningkatkan partisipasi seluruh masyarakat dalam pengelolaan mangrove sesuai dengan peran dan fungsinya, (3) memberikan penyuluhan kepada
Keyword: definisi mangrove, jenis mangrove, hutan mangrove, partisipasi masyarakat, masyarakat pesisir

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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