Judul: Nilai-nilai Keluarga, Kecerdasan Emosional (EQ) Anak, dan Faktor-faktor yang Mempengaruhinya (Kasus di SDN Kotamadya Bogor)
Abstrak: Secara umum penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi nilai-nilai keluarga (family values) dan pengaruhnya terhadap kecerdasan emosional anak usia sekolah. Secara khusus penelitian ini bertujuan untuk mengetahui perbedaan faktor sosial ekonomi, faktor karakteristik keluarga, nilai-nilai keluarga dan kecerdasan emosional (EQ) anak antara tiga kelompok sekolah berdasarkm status sosial ekonomi (kelompok I, II dan III), mengetahui pengasuh faktor sosial ekonomi keluarga dan faktor karakteristik keluarga terhadap nilai-nilai keluarga dan mengetahui pengaruh nilai-nilai keluarga, faktor sosial ekonomi dan faktor karakteristik keluarga terhadap kecerdasan emosional anak usia sekolah.
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Judul: Kemampuan Kognitif dan Kecerdasan Emosional Serta Faktor-faktor yang Mempengaruhinya di Sekolah Dasar Negeri, Kota Bogor
Abstrak: Secara umum penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kemampuan kognitif dan kecerdasan emosional anak dari keluarga dengan strata sosial ekonomi tinggi, sedang dan rendah. Tujuan khususnya adalah: 1). mengetahui perbedaan karakteristik keluarga yang diwakili oleh ibu antar strata sosial ekonomi keluarga, 2). mengetahui perbedaan kemampuan kopnitif dan kecerdasan emosional anak antar strata sosial ekonomi keluarga, 3). mengetahui faktor-faktor yang mempengaruhi kemampuan kognitif anak antar strata sosial ekonomi keluarga, dan 4). mengetahui faktor-faktor yang mempengaruhi kecerdasan emosional anak antar strata sosial ekonomi keluarga.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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