Judul: Perubahan Paras Muka Laut dan Dampaknya Terhadap Genangan di Daratan Pesisir Kota Semarang, Jawa Tengah
Abstrak: Sea level changing along the time with Mean Sea Level (MSL) shows increasing trend. Semarang City that facing subsidence also impacted by the change of sea level in term of sea level rise and tides. The recorded and reconstructed data (from CSIRO) shows that global sea level rose to 6.83 cm by Dec-2009. Regional sea level change data from University of Colorado also shows the increasing trend of sea level. Three months (Dec-2011 to Feb-2012) realistic tides model that has been generated using FVCOM shows the highest level of the sea surface was 0.473 m while measured sea level in coastal water area of Semarang City by 2010 was 94.669 cm. Measured sea level has to be corrected because the area where it measured experiencing land subsidence. Correction result shows isostatic mean sea level in 2010 was 52.070 cm. Subsidence rate in the location where sea level has measured (Tanjung Mas) can be estimate with the deviation between mean sea level data from tide gauge that experiencing subsidence and isostatic sea level. The result of estimation shows subsidence rate in Tanjung Mas is 7.1 cm/year. The impact of sea level change until 2011 has been formed 1,043.527 Ha of submergence area. Projection in the future shows that in next ten years submergence area will reach ± 3,627 Ha while in next 15 years submergence area will reach ± 4,364 Ha and in next 20 years submergence area will reach ± 4,641 Ha. When spring tides occur, the impact of sea level change will getting worst because area with altitude up to 0.47 from submergence area will be inundated by seawater.
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Judul: Penilaian Dampak Kenaikan Muka Air Laut Terhadap Wilayah Pesisir (Studi Kasus : Kota Semarang)
Abstrak: Sea level rise is one of important global issue now. It has been caused by ice melting in pole, climate extreme event, and land level decreasing. Coastal area have high vulnerability effect by sea level rise. Coastal area is important to support the economic development country. If the sea level rise was happened so many properties that losses. The problem like land use losses, people evacuation, diseases, sanitation, and economic losses will appear. Sea level rise can be forecasted by satellite imagery like ENVISAT, Topex/Poseidon, Jason1 and Jason2. All of the data can be processed by one of adds on in Microsoft Excel software. Flooded area was created by DEM SRTM data with 30 x 30 meter resolution. The result show that sea level rise 0,69 mm/year happened in Semarang. The forecasting result at 2100 in Semarang show change to be flooded area 1,8 km. The economic losses can be computed by describe land of use. The result show that economic losses is IDR 6,7 billion or IDR 36 million per hectare in 2100. 145 people will be evacuated if it’s happened. Physically adaptation like house type changing and create sea wall also non physically adaptation by creating relocation area will be needed to prepare if the forecast become real.
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Judul: Pemurnian Rekombinan Eritropoietin Manusia (rhEPO) Menggunakan Kromatografi Afinitas Ni-NTA dan Co-Talon
Abstrak: Suitable and efficient techniques for purification of recombinant human erythropoietin (rhEPO) are required to obtain pure rhEPO which can be continued to preclinical trials step. One of these techniques is immobilized metal affinity chromatography (IMAC), which has advantages such as high selectivity, easy to elute, and simple procedure for column regeneration. At least, there are 2 kinds of commercial IMAC resin using nitriloacetic acid (NTA) matrix as chelating agent, namely nickel-based (Ni-NTA) and cobalt-based IMAC resin (Co-NTA), the latter is well known as Talon. This research studied the influence of metal ions Ni2+ and Co2+ in rhEPO purification. The results indicated that Ni- NTA had higher affinity in binding rhEPO protein compared with Co-Talon. Average total protein by Ni-NTA was 226.72 μg/mL and Co-Talon was 60.52 μg/mL, but the protein purity with Co-Talon was better than Ni-NTA. Base on protein yield that can be separated, Ni-NTA is more suitable to obtain high yield of rhEPO protein.
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