Judul: Gambaran Histopatologi Organ Hati dan Ginjal Setelah Pemberian Ekstrak Ethanol Sirih Merah dan Diuji Tantang Virus AI H5N1
Abstrak: The objective of this study was to determine the potency of Piper crocatum ethanolic extract (PC) to prevent virus infection, and to describe the liver and kidney histopathology of broiler after challenged by H5N1 virus. There were four group treatments in this study, such as K1 (Positive Control), K2 (Negative Control), P1 (Chickens PC treatment and challenged by H5N1 virus), and P2 (Chicken PC treatment). The histopathological data was processed by Kruskall Wallis statistical analysis followed by Dunn test. Based on mortality data, PC in a single composition capable to reduce mortality up to 62.5%. Histopathological lesion that appeared in liver and kidney were congestion, cell degeneration, and necrose. It can be concluded that PC able to prevent the death of chicken due to infection of H5N1 virus, however remain lesion in the liver and kidney.
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Judul: Kajian Histopatologi Paru–Paru Ayam Broiler yang Diuji Tantang Virus Avian Influenza (H5N1) Setelah Pemberian Ekstrak Tanaman Sirih Merah (Piper Crocatum)
Abstrak: This research aim was to study the histopathological features of lungs in broiler that challenged by Avian Influenza (AI) H5N1 virus after treatment with sirih merah (Piper crocatum) extract. Fourteen Cobbs of broiler were divided into 4 groups treatment included negative control (KN) who were not given the sirih merah extract and not challenged by AI virus, positive control (KP) who were not given the sirih merah extract but challenged by AI virus, negative treatment (PN) who were given the sirih merah extract but not challenged by AI virus, positive treatment (PP) who were given the sirih merah extract and challenged by AI virus. Treatment of the sirih merah (Piper crocatum) 10% extract/ml/head broiler was for three weeks per os and then challenged with Avian Influenza H5N1 virus 104,0 EID50/0,1 ml per head intra nasal in BSL-3 facilities. The result of this research showed that the histopathological features of lung in broiler group PP would be similar to the KN with the congestion and oedema, however lesser than those PN whereas oedema was not shown. The KP group showed the worst lesion than other groups with necrose in the alveol. Based on the statistical analysis showed that KP group was significantly different compared to the KN group however no significantly different while compared to the PP and PN. In conclusion, the treatment of sirih merah (Piper crocatum) extract to broiler followed by challenging with AI H5N1 virus can reduce the mortality and damage of lungs organ.
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Judul: Metrik Einstein (Anti-) Self-Dual Berdimensi Empat dengan Metode Cartan
Abstrak: Gravitational field equation can be formulated in differential forms (differential geometry), which describes gravity as a manifestation of the curvature of space-time. Curvature of space-time is characterized by a metric that satisfies the gravitational field equation. With differential forms it can be formulated the (anti-) self-dual Einstein equation, which is a modification of the Cartan structure in (anti-) self-dual basis. Calculation of (anti-) self-dual metric with (anti-) self-dual Einstein equation is simpler than the calculation using Christoffel symbols.
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