Judul: Faktor-faktor yang Memengaruhi Keputusan Pembelian Kosmetik Berlabel Halal MUI pada Generasi Milenial Kota Jakarta Barat
Abstrak: Kosmetik merupakan salah satu kebutuhan sehari-hari yang rutin dibeli oleh perempuan generasi milenial. Namun, di Kota Jakarta Barat masih ditemukan produk kosmetik palsu dan ilegal serta tidak memiliki label halal sehingga produk tersebut belum terjamin kehalalannya serta bahan-bahan yang terkandung masih diragukan. Penelitian ini bertujuan mengidentifikasi karakteristik generasi milenial Jakarta Barat serta menganalisis faktor-faktor yang memengaruhi generasi milenial Kota Jakarta Barat dalam pengambilan keputusan pembelian kosmetik berlabel halal MUI. Sampel penelitian ini berjumlah 100 responden yang berdomisili di Kota Jakarta Barat. Metode yang digunakan dalam penelitian ini adalah analisis deskriptif dan analisis regresi logistik. Hasil penelitian menunjukkan bahwa variabel religiusitas, persepsi label halal, kelompok acuan, dan gaya hidup berpengaruh positif dan signifikan terhadap keputusan pembelian kosmetik berlabel halal MUI oleh generasi milenial Kota Jakarta Barat., Cosmetics is one of the daily necessities that are routinely purchased by female of millennial generation. However, in the City of West Jakarta, fake and illegal cosmetic products are still found and do not have a halal label so that the product is not guaranteed to be halal and the ingredients contained are still in doubt. This study aims to identify the characteristics of the millennial generation in West Jakarta and analyze the factors that influence the millennial generation in the city of West Jakarta in making decisions to purchase cosmetics labeled halal MUI. The sample of this study amounted to 100 respondents who live in the city of West Jakarta. The method used in this research is descriptive analysis and logistic regression analysis. The results showed that the variables of religiosity, perception of halal labels, reference groups, and lifestyle had a positive and significant effect on purchasing decisions for cosmetics labeled with halal MUI labels by the millennial generation of West Jakarta City.
Keyword: Halal-labelled cosmetics, Logistics regression, Millennial generation, Purchase decision

Judul: Faktor-faktor yang  Memengaruhi Keputusan Pembelian Kosmetik Halal oleh Generasi Milenial di  Jabodetabek
Abstrak: Penjualan produk kosmetik mengalami peningkatan sebesar 14,3% pada tahun 2022 dan Indonesia menempati peringkat kedua untuk kategori kosmetik halal. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi keputusan pembelian kosmetik halal oleh generasi milenial di Jabodetabek, dengan mengambil sampel sebanyak 100 responden. Metode yang digunakan dalam penelitian ini adalah analisis deskriptif dan regresi logistik. Hasil penelitian menunjukkan bahwa faktor yang berpeluang memengaruhi keputusan pembelian kosmetik halal oleh generasi milenial di Jabodetabek adalah variabel pendidikan, halal awareness, promosi, dan produk., Sales of cosmetic products increased by 14,3% in 2022 and Indonesia ranked second in the halal cosmetics category. This study aims to analyze the factors that influence the decision to purchase halal cosmetics by the millennial generation in Jabodetabek, by taking a sample of 100 respondents. The methods used in this study are descriptive analysis and logistic regression. The research results show that the factors that influence the decision to purchase halal cosmetics by the millennial generation in Jabodetabek are education, halal awareness, promotion and product variables.
Keyword: halal cosmetics, logistic regression, millennial generation, purchasing decision

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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