Judul: Marketing Strategy of Kelor Tiga Coffee & Plants Coffee Shop in Bogor City
Abstrak: Konsumsi kopi di Indonesia terus meningkat setiap tahun, hal ini menunjukkan adanya peningkatan minat masyarakat Indonesia terhadap produk- produk kopi yang menciptakan peluang bisnis yang menarik bagi para pengusaha, seperti bisnis kedai kopi. Salah satu contoh usaha kedai kopi di Kota Bogor adalah Kelor Tiga Coffee & Plants. Keberadaan banyak kedai kopi memicu persaingan di Kota Bogor. Tujuan penelitian ini adalah mengidentifikasi faktor-faktor internal dan eksternal Kelor Tiga Coffee & Plants, merumuskan strategi alternatif, hingga penetapan prioritas strategi pemasaran yang dapat diimplementasikan perusahaan. Metode yang digunakan pada penelitian ini adalah analisis deskriptif dan analisis tiga tahap formulasi strategi, yang terdiri dari tahap masukan, tahap pencocokan dan tahap keputusan. Alat analisis yang digunakan pada penelitian ini adalah matriks IFE, matriks EFE, matriks IE, matriks SWOT, dan QSPM. Hasil analisis menunjukkan bahwa Kelor Tiga Coffee & Plants berada dalam posisi tumbuh dan kembangkan. Berdasarkan matriks SWOT, didapatkan hasil sembilan alternatif strategi pemasaran dengan prioritas strategi, yaitu memperluas jangkauan pasar dengan media sosial dari hasil perhitungan QSPM., Coffee consumption in Indonesia continues to increase every year, this shows the increasing interest of Indonesian people in coffee products which creates attractive business opportunities for entrepreneurs, such as the coffee shop business. One example of a coffee shop business in Bogor City is Kelor Tiga Coffee & Plants. The existence of many coffee shops triggers competition in the city of Bogor. The aim of this research is to identify internal and external factors for Kelor Tiga Coffee & Plants, formulate alternative strategies, and determine marketing strategy priorities that the company can implement. The method used in this research is descriptive analysis and analysis of three stages of strategy formulation, consisting of the input stage, matching stage and decision stage. The analytical tools used in this research are the IFE matrix, EFE matrix, IE matrix, SWOT matrix, and QSPM. The analysis result shows that Kelor Tiga Coffee & Plants is in a position to grow and build. Based on the SWOT matrix, the results obtained were nine alternative marketing strategies with priority strategy, namely expanding market reach with social media from the QSPM calculation results.
Keyword: Coffee Shop, Marketing Strategy, Priority Strategy

Judul: Marketing Mix Strategy of Kopi Yor Coffee Shop Analysis (Case Study : Kopi Yor, Bogor City, West Java)
Abstrak: Industri makanan dan minuman merupakan industri yang sangat diminati banyak penggiat bisnis. Salah satunya yaitu kedai kopi yang berkembang cukup pesat saat ini karena menjadi salah satu gaya hidup kaum milenial. Kopi Yor Sempur merupakan kedai kopi yang terletak di daerah Kota Bogor. Lokasi Kopi Yor Sempur bertempat di sekitaran perumahan dan juga berdekatan dengan tempat olahraga umum di Bogor sehingga lokasinya strategis untuk mendapatkan konsumen. Pihak pengelola Kopi Yor Sempur menyadari dengan konsep dan lokasi yang dimiliki saat ini tetap harus mampu beradaptasi dengan keadaan yang selalu berkembang. Salah satu bentuk adaptasi yang bisa dilakukan adalah dengan merumuskan strategi pemasaran agar Kopi Yor Sempur tetap mendapatkan konsumen di tengah persaingan kedai kopi yang ada. Penelitian ini dilakukan untuk mengetahui strategi pemasaran yang tepat agar Kopi Yor Sempur dapat beradaptasi dengan perkembangan pasar yang ada. Alat analisis yang digunakan dalam penelitian ini adalah analisis faktor internal dan eksternal (IFE dan EFE), matriks IE, serta QSPM. Penelitian yang dilakukan menghasilkan beberapa strategi alternatif yaitu, membuat slogan, promosi menu pada jam tertentu menambah meja outdoor, meningkatkan kualitas SDM serta membuat promosi dengan paket bundling. Hasil dari perhitungan matriks QSP menunjukan urutan prioritas paling tertinggi berada pada strategi alternatif membuat promosi kategori kelompok dengan nilai STAS sebesar 6,630. Kata Kunci: IFE dan EFE, kedai kopi, matriks IE, strategi pemasaran, QSPM., The food and beverage industry is an industry that is in great demand by many business people. One of them is a coffee shop that is growing quite rapidly at this time because it has become one of the millennial lifestyles. Yor Sempur Coffee is a coffee shop located in the Bogor City area. The location of Kopi Yor Sempur is located in a residential area and also close to public sports venues in Bogor so that the location is strategic to get consumers. The management of Kopi Yor Sempur realizes that with the current concept and location, it must be able to adapt to conditions that are always evolving. One form of adaptation that can be done is to formulate a marketing strategy so that Yor Sempur Coffee continues to get consumers in the midst of competition from existing coffee shops. This research was conducted to find out the right marketing strategy so that Yor Sempur Coffee can adapt to existing market developments. The analytical tool used in this research is the analysis of internal and external factors (IFE and EFE), IE matrix, and QSPM. The research carried out resulted in several alternative strategies, namely, making slogans, promoting menus at certain hours, adding outdoor tables, improving the quality of human resources and making promotions with bundling packages. The results of the QSP matrix calculation show that the highest priority order is in the alternative strategy of making group category promotions with a STAS value of 6.630. Keywords: coffee shop, IFE and EFE, IE matrix, marketing strategy, QSPM.
Keyword: IFE dan EFE, kedai kopi, matriks IE, strategi pemasaran, QSPM

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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