Judul: Garden Design for Al Muttaqin Grand Mosque, Bogor City
Abstrak: Meningkatnya pertumbuhan penduduk yang semakin pesat di perkotaan menimbulkan berbagai kebutuhan baru yang timbul akibat kebutuhan ruang pada masyarakat. Kebutuhan ruang publik menjadi salah satu yang harus dipenuhi dan menjadi aspek penting yang tidak dapat dilupakan. Masjid Al Muttaqin memiliki fungsi utama sebagai tempat beribadah umat islam. Selain itu, masjid memiliki fungsi tambahan sebagai area ruang terbuka publik yang digunakan masyarakat sekitar untuk berbagai aktivitas. Oleh karena itu, diperlukan penunjang aktivitas berupa taman yang dapat mendukung kegiatan bersosialisasi masyarakat dan menjadi ruang terbuka yang mengakomodasi kebutuhan masyarakat sekitar akan ruang terbuka publik. Penelitian ini bertujuan untuk mengidentifikasi karakteristik lanskap Masjid Raya Al Muttaqin Bogor, menganalisis potensi dan kendala taman Masjid Raya Al-Muttaqin serta mendesain taman Masjid Raya Al-Muttaqin.. Metodelogi yang digunakan mengacu pada Simonds dan Starke (2006) yang disesuaikan, yaitu inventarisasi, analisis, sintesis, konsep, dan desain. Konsep dasar Taman Masjid Raya Al-Muttaqin ialah Islamic Garden. Hasil penelitian ini berupa karakteristik lanskap secara deskriptif dan spasial, analisis tapak secara deskriptif dan spasial, serta siteplan yang dilengkapi dengan gambar ilustrasi, potongan, perspektif, dan detail engineering desain., Population growth in urban area raises various needs to the requirement for space in the community. The requirement for public space is one that must be met and considered as an important aspect that cannot be forgotten. Al Muttaqin Mosque has the main function as a place of worship for Muslims. Furthermore, the mosque has additional function as public open space area used by the surrounding community for various activities. Therefore, it is necessary to support activities in the form of a park that can support community socialization activities and at the same time become an open space that accommodates the needs of the surrounding community for public open space. This study aims to identify the landscape characteristics of the Al Muttaqin Grand Mosque in Bogor, analyze the potential and constraints of the Al-Muttaqin Grand Mosque garden and design the Al- Muttaqin Grand Mosque garden. The methodology used refers to Simonds and Starke (2006) which is adjusted, namely inventory, applied synthesis, concept, and design. The basic concept of the Al-Muttaqin Grand Mosque Park is the Islamic Garden. The result of the study are descriptive and spatial characteristics of the landscape, descriptive and spatial site analysis, Islamic garden concept and a site plan equipped with illustrations, sections, perspectives, and engineering design details.
Keyword: garden design, mosque, public space, islamic garden

Judul: Landscape Design of Dian Al-Mahri Golden Dome Mosque based on Islamic Garden Concept
Abstrak: Depok merupakan salah satu kota dengan mayoritas penduduk muslim. Masjid merupakan kebutuhan ibadah yang penting bagi penduduk muslim dan lanskapnya dapat menjadi ruang terbuka publik yang menarik. Desain lanskap masjid perlu diperhatikan karena mempengaruhi nilai fungsional dan estetika area masjid, salah satunya yang terbesar di Kota Depok adalah Masjid Kubah Emas Dian Al-Mahri. Tujuan dari penelitian ini adalah untuk mengidentifikasi dan menganalisis potensi dan kendala yang ada pada lanskap Masjid Kubah Emas Dian Al-Mahri, menganalisis karakteristik lanskap, dan membuat desain lanskap masjid berdasarkan konsep taman islami. Tahapan penelitian ini meliputi persiapan, inventarisasi, analisis, sintesis, dan penyusunan desain lanskap. Konsep dasar dari penelitian ini adalah taman islami yang menerapkan ‘darasa’ atau pembelajaran Islam sebagai kegiatan utama di dalamnya. Konsep desain menerapkan arabesk dan bentuk geometris pada pola ruang, sirkulasi, bentuk elemen, dan motif elemen. Desain lanskap dalam penelitian ini dimaksudkan untuk menyediakan ruang ibadah, pendidikan Islam, sosialisasi, dan wisata. Hasil penelitian ini juga dibatasi pada pembuatan siteplan, gambar potongan, detail engineering design (DED), ilustrasi 3 dimensi dan ilustrasi pendukung lainnya., Depok is one of the cities with a majority of muslim population. Mosque is an important worship needs for muslims and the landscape can be an attractive public open space. The mosque landscape design needs to be concerned because it affects both the functional and aesthetic values of the mosque area, which one of the greatest ones is Dian Al-Mahri Golden Dome Mosque. The purpose of this research is to identify and analyze the potential and constraints that exist in Dian Al-Mahri Golden Dome Mosque landscape, to analyze the landscape’s characteristics, and to create a landscape mosque design based on Islamic Garden concept. The stages of this research include preparation, inventory, analysis, synthesis, and preparation of landscape designs. The basic concept of this research is an Islamic Garden which applies 'darasa' or learning as the main activity in it. The design concept applies arabesque and geometric shapes to spatial patterns, circulation, elemental shapes, and elemental motifs. landscape design in this research is intended to provide spaces for worship, Islamic education, socialization, and tourism. The results of this study are also limited to the creation of a site plan, section drawings, detailed engineering design (DED), and other supporting illustrations.
Keyword: Islamic Garden, Landscape Design, Mosque

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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