Judul: Correlation between the Changes of Green Open Space and the Level of Development of Infrastructures and Service Facilities in South Jakarta
Abstrak: Kota-kota di seluruh wilayah Indonesia, khususnya Kota Administrasi Jakarta Selatan, DKI Jakarta terus berkembang dengan pesat. Salah satu bentuk pertumbuhan fisik wilayah perkotaan adalah perubahan penggunaan lahan, diantaranya perubahan lahan ruang terbuka hijau atau lahan bervegetasi menjadi lahan terbangun. Tujuan penelitian adalah 1). mengidentifikasi pola dan laju perubahan lahan ruang terbuka hijau, 2). mengetahui hierarki dan perkembangan prasarana atau fasilitas pelayanan, 3). mengetahui hubungan luas RTH dengan perkembangan prasarana dan fasilitas pelayanan, pertumbuhan penduduk dan peruntukan tata ruang di Jakarta Selatan. Penelitian ini dilakukan dengan analisis sistem informasi geografi (overlay) peta tutupan lahan tiap titik tahun dengan peta administrasi, teknik pendugaan pertumbuhan, analisis skalogram, dan analisis korelasi. Hasil penelitian menunjukkan bahwa perubahan lahan ruang terbuka hijau menjadi penggunaan lahan lain terutama lahan terbangun terus terjadi pada setiap titik tahun terpilih. Pada tahun 2000, total luas lahan RTH adalah sebesar 2.580,11 ha, lalu turun menjadi 2.283,01 ha tahun 2005, dan kembali turun pada tahun 2010, 2015 dan 2018 menjadi berturut-turut 2.149,04 ha, 1.430,38 ha, dan 1.312,76 ha. Laju pertumbuhan RTH mengalami penyusutan. Laju penyusutan luas tertinggi terjadi pada periode 2010-2015, yaitu sebesar 19,08% sedangkan laju penyusutan luas terendah terjadi pada periode 2000-2005, sebesar 13,81%. Secara umum, laju penyusutan luas lahan RTH di Jakarta Selatan pada tahun 2000 hingga 2018 adalah 3,74% per tahun. Kecamatan dengan laju penyusutan RTH tertinggi adalah Kecamatan Kebayoran Baru, yaitu sebesar 68,41% sedangkan yang terendah adalah Kecamatan Kebayoran Lama sebesar 29,90%. Peningkatan jumlah prasarana atau fasilitas pelayanan di Jakarta Selatan juga terus terjadi. Hal ini terlihat dari nilai indeks perkembangan kecamatan (IPK) dan hierarki wilayah di beberapa kecamatan yang mengalami peningkatan. Pada tahun 2001 terdapat satu kecamatan berhierarki I, kemudian bertambah menjadi tiga kecamatan pada tahun 2006. Selanjutnya pada tahun 2011, jumlah kecamatan berhierarki I turun menjadi dua kecamatan dan tidak terjadi perubahan pada tahun 2014. Namun, jumlah kecamatan berhierarki I kembali turun menjadi satu kecamatan pada tahun 2018. Perubahan jumlah kecamatan juga turut terjadi pada hierarki II dan III dengan kecenderungan kecamatan-kecamatan di wilayah Jakarta Selatan berada dalam hierarki III. Hasil analisis korelasi menunjukkan tidak adanya korelasi yang signifikan antara luas RTH dengan perkembangan prasarana dan fasilitas pelayanan, laju pertumbuhan penduduk maupun dengan alokasi RTH dalam RTRW., Throughout Indonesia, especially the Administrative City of South Jakarta, DKI Jakarta continues to overgrow. One form of physical growth in urban areas is land-use change, including changes in green open space or vegetated area into the built-up area. The purpose of this research is to identify the pattern and rate of change of green open space, to know the hierarchy and development of infrastructure and service facilities, and to find out the correlation between the area of green open space and the development of infrastructure and service facilities, population growth and spatial planning in South Jakarta. This research overlays land use maps from each year with administrative maps, growth estimation techniques, scalogram analysis, and correlation analysis. The study results indicate that changes in land use of green open spaces into other land uses, mainly built-up areas, continue to occur at every point of the year. In 2000, the total size of
Keyword: analisis korelasi, Jakarta Selatan, perkembangan wilayah, RTH, correlation analysis, South Jakarta, regional development, Green Open Space

Judul: An Analysis of Changing on Greenery Open Space Area and Factors Influence It In South Jakarta
Abstrak: South Jakarta is one of region in DKI Jakarta facing an enormous growth in all aspects of development. The increasing of development activities and regional cause increase land uses dynamic. Fixed land supply compare with the increasing demand causing land use change particularly greenery open space in South Jakarta. This research aims are: (1) to identify changing of greenery open space of South Jakarta, and (2) to find out population, infrastructure, and development growth rate of South Jakarta; and (3) to identify factors influencing change of greenery open space and relationship among the factors. The result shows that greenery open space in the period of 2002-2007 decreased about 362,21 hectare from 1299,22 hectares in 2002 to 937,01 hectares in 2007. In the same period population and population density increased 0,7% per year while immigrants declined -23% per year. The region of South Jakarta in 2003 showed hierarchy III village was dominant (43 villages), while number of hierarchy II and I village was 17 villages and 5 villages. In 2006 number of village categorized on hierarchy II showed increasing to be 19 villages while hierarchy III decreasing to be 41 villages and hierarchy I was constant in number. Regional development could be due to growth on infrastructure development such as educational facility, health facility, and commercial area. The number of educational, health, and commercial facilities grew during the period of 2003- 2006 with rate 4,8%, 7,1%, and 20% per year, respectively. Regression analysis was utilized to identify factors influencing greenery open space area change. According to the result, land allocated for greenery open space in Jakarta’s spatial plan (RTRW) being the major factor affecting the change. The other factors were growth of health facilities, immigrants, population density, and educational facilities.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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