Judul: Persepsi Masyarakat terhadap Media Luar Ruang di Jalan Margonda Raya Kota Depok sebagai Media Periklanan
Abstrak: The research about people’s perception was conducted in order to identify the existence of outdoor media in Margonda Raya Street, Depok City, West Java. Quantitative method was used as the primary method in this research. This research was conducted using survey research design with descriptive-correlational approach. Descriptive in this research means describing respondent characteristics, people’s perception toward visual communication aspects, typology characteristics, and outdoor media aesthetics. Moreover, Correlational in this research means trying to explore factors that related to people’s perception and try to examine correlation between variables. By identifying people’s perception, it will enable us to describe people’s response toward outdoor media. As many as 94 respondents from Margonda Raya Street, Depok City was selected as sample in this research. The research results showed that the public perception of visual communication aspects on outdoor media is good, while the public perception of the outdoor media typology and aesthetic outdoor media is good enough. Further study related to outdoor media is expected to learn about outdoor media in Depok City based on City Planning (RTRK).
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Judul: Rencana pengelolaan lanskap jalan Margonda Raya, Kota Depok, Jawa Barat
Abstrak: Kawasan Jalan Margonda Raya sebagai lokasi studi, merupakan jalan penghubung utama, bahkan dapat dikatakan sebagai landmark dari Kota Depok. Potensi jalan ini cukup besar untuk terus berkembang dengan terlihat banyak didirikannya bangunan baru sepanjang jalan ini. Letak jalan ini sangat strategis karena merupakan jalur masuk utama dari dan ke Kota Jakarta serta pintu gerbang menuju Kota Depok. Penelitian ini bertujuan untuk menginventarisasi dan menganalisis fungsi dan estetika lanskap Jalan Margonda Raya, Kota Depok, Jawa Barat, serta untuk menyusun rencana manajemen lanskap yang dapat dipertimbangkan demi keberlangsungan potensi jalan tersebut di masa depan. Hasil penelitian ini diharapkan akan bermanfaat dalam memberikan masukan positif khususnya pada Dinas Kebersihan dan Pertamanan Kota Depok selaku pihak yang terkait dengan pengelolaan lanskap Jalan Margonda Raya, Kota Depok, Jawa Barat dalam melaksanakan proses manajemen lanskap jalan. Studi rencana pengelolaan lanskap jalan ini dilakukan pada kawasan sepanjang Jalan Margonda Raya, Kota Depok, Jawa Barat dimana fungsi jalan ini sebagai jalan kolektor primer, dengan panjang jalan 5,2 km dan lebar beragam (18,5-30 m). Metode yang digunakan pada penelitian ini bersifat deskriptif dan dilakukan dengan metode survei yang mencakup empat tahap, yaitu tahap persiapan, pengumpulan data (survei), analisa data, dan pembuatan usulan konsep rencana pengelolaan. Secara geografis Jalan Margonda Raya sebagai lokasi studi terletak di Kota Depok pada koordinat antara 6°21'00" -6°24'00" Lintang Selatan dan 106° 49'00" - 106° 50'00" Bujur Timur. Tapak lokasi penelitian mempunyai luas area penanaman sebesar 11.118,3 m². Kota Depok termasuk daerah beriklim tropis dengan perbedaan curah hujan yang cukup kecil dan dipengaruhi oleh iklim muson. Secara umum musim kemarau terjadi antara bulan April-September dan musim hujan antara bulan Oktober-Maret...dst
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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