Judul: Evaluation of Effective Dose of Ketamine- Xylazine Combination Anesthesia in Pediatric Rats
Abstrak: Anestesi efektif mengurangi stres dan rasa sakit pada tikus dengan menghilangkan kesadaran. Kombinasi yang umum digunakan dalam penelitian adalah Ketamine dan Xylazine. Kombinasi ini telah banyak digunakan pada tikus dewasa dengan berbagai dosis, tetapi belum ada acuan dosis tepat untuk tikus pediatri. Penelitian ini bertujuan mendapatkan dosis anestesi dari kombinasi Ketamine-Xylazine yang efektif dan aman untuk tikus pediatri. Penelitian menggunakan 25 ekor tikus berumur 3 minggu yang dibagi menjadi 5 kelompok perlakuan, yaitu kelompok negatif dan 4 perlakuan dosis Ketamine (25, 50, 75, dan 100 mg/kg BB) dikombinasikan dengan Xylazine 4 mg/kg BB. Hasil penelitian menunjukkan efek anestesi tikus pediatri baru mulai muncul setelah pemberian dosis Ketamine 50 mg/Kg BB. Kondisi fisiologis (frekuensi jantung, frekuensi napas, dan suhu tubuh) mengalami penurunan pada 10 menit setelah injeksi anestesi dan seiring waktu berangsur kembali ke normal. Pada dosis yang tinggi (100 mg/kg BB), terjadi kematian pasca injeksi dengan tingkat kematian 40%. Dosis anestesi Ketamine-Xylazine yang disarankan adalah 50–75/4 mg/kg BB.
Keyword: rat, xylazine, pediatric, dose, ketamine

Judul: Efektivitas Anestetikum Kombinasi Zoletil-Ketamin-Xylazin pada Babi Lokal (Sus domestica) Indonesia
Abstrak: The purpose of this research was to evaluate the potential of zoletil-ketamine-xylazine combination as anesthetic in Indonesian local pig. Nine local pigs were subjected to three groups of treatment. Each group consisted of three pigs. The first groups (A) anesthetized with ketamine-xylazine combination (ketamine 15 mg/kg BB and xylazine 2 mg/kg BB). The second group (B) anesthetized with zoletil-ketamine-xylazine combination (zoletil 4 mg/kg BB, ketamine 2 mg/kg BB, and xylazine 2 mg/kg BB). The third group (C) anesthetized with ketamine-xylazine (ketamine 10 mg/kg BB and xylazine 1 mg/kg BB). The measured variables were symptoms during the induction symptoms, onset and duration anesthesia, body temperature, heart rate, and respiration frequency. However anesthesia protocol of group C were unable to anesthetized the Indonesian local pigs. The combination of lower dose ketamine-xylazine in group C only resulted in sedated condition. The results showed that were no significant difference between the treatment groups A and B.
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Judul: Kekonsistenan Hamiltonian pada Gerak Gelombang Interfacial
Abstrak: The interfacial wave is an internal wave that occurs at boundary of two layers fluid. It appears because there is difference of mass density between the two layers. The objective of this thesis is to formulate the motion of internal wave with flat base and flat as well as free upper bound surface. The motion equation obtained is a Hamiltonian system. The Hamiltonian in this system is expressed by variable of wave deviation and horizontal component of potential velocity. Under assumption that interfacial wave moves only in one direction, it can be shown that the Hamiltonian depends on the solution of the wave motion equation. The coefficients of the equation depend on the physical characteristics of the two layers of fluid, i.e. thickness and mass density. The numerical results show that Hamiltonian in the system is constant. It is consistent with Hamiltonian characteristic, which does not depend on time.
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