Judul: Optimisasi Ekstraksi Cair-Cair Fraksi Etanol Daun Dandang Gendis (Clinacanthus nutans)
Abstrak: Dandang gendis (Clinacanthus nutans) is a herb which contains antimalaria and larvacide bioactive compounds. In this study, the dried leaf powder was macerated with ethanol and then partitioned with n-hexane. The resulting ethanol extract was then partitioned again with ethyl acetate and this liquid-liquid extraction procedure was the subject of the optimization. Sample to solvent ratio (1:2, 1:3, and 1:4 (mL/mL), extraction temperature (30, 40, and 50 °C); and extraction repetition (1, 2, and 3 times) variations effect were studied. The bioactivity of the extracts were tested with brine shrimp lethality test (BSLT) using Artemia salina. The BSLT result of the 11th extract showed the optimum LC50 value (59.15 mg/L). This extract was obtained from the extraction procedure using 1:4 (mL/mL) sample to solvent ratio, 40 °C temperature, and 3 times repetition. From the Minitab 15 computation results were predicted that the optimum condition is achieved at 1:3.88 – 1:4.00 (mL/mL) sample to solvent ratio, 4.61 – 49.99 °C extraction temperature, and 3 times extraction repetition with LC50 170.19 mg/L. The phytochemistry test results showed that the 11th extract contains alkaloids, flavonoids, saponins, and steroids.
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Judul: Uji Toksisitas Ekstrak Etil Asetat Teraktif Daun Dandang Gendis (Clinacanthus nutans) Menggunakan Uji Letalitas Larva Udang
Abstrak: Dandang gendis (Clinacanthus nutans) is a medical herb commonly used as a traditional medicine as antimalarial and antidiabetic. This study was started with maceration of the dried leaves of dandang gendis with ethanol,and then partitioned using n-hexane. The ethanol extract free of nonpolar compounds was then partitioned with ethyl acetate. The ethanol crude extract, n-hexane fraction, and ethyl acetate fraction were tested by using brine shrimp lethality test to determine the toxicity of each extract. The ethyl acetate fraction showed the highest activity with 50% lethal concentration (LC50) of 32 mg/L. Re-extraction of ethanol extract free of nonpolar compounds by using ethyl acetate in 90 minutes by three times extraction with material:solvent ratio of 1:2 resulted LC50 value of 29.02 mg/L. Phytochemical assay results showed that the ethyl acetate extract of dandang gendis leaves contained saponins, alkaloids, steroids, and flavonoids. Re-extraction of ethyl acetate extract contained higher flavonoids than ethyl acetate extract from the first extraction.
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Judul: Perilaku Remaja Tahap Awal dalam Menonton Televisi dan Hubungannya dengan Penggunaan Waktu Mereka untuk Kegiatan Sehari-hari (Kasus Siswa SMPN Cibungbulang, Kabupaten Bogor Jawa Barat)
Abstrak: Perkembangan teknologi komunikasi massa terutama televisi sangat pesat. Perkembangan televisi di satu sisi mendorong timbulnya era baru bagi masyarakat yaitu dengan globalisasi informasi, namun pada sisi lain memberikan masalah. Adapun masalah yang dikemukakan pada penelitian ini adalah: (1) Bagaimana pola menonton televisi di kalangan remaja ? . (2) Bagaimana pengaruh menonton televisi terhadap penggunaan waktu remaja ? . Tujuan penelitian ini adalah: (1) Mengidentifikasi pola menonton televisi pada diri remaja. (2) Mengidentifikasi pengaruh menonton televisi terhadap penggunaan waktu remaja.
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