Judul: Kajian Potensi Ekstrak Tanaman Tanaman Obat Sambiloto (Andrographis paniculata Ness) dan Beluntas (Pluchea indica Less) Sebagai Alternatif Bahan Obat Flu Burung:
Abstrak: Avian Influenza (AI) atau flu burung merupakan penyakit yang menyita perhatian dunia beberapa tahun terakhir ini, khususnya Indonesia. Kasus flu burung pada manusia di Indonesia terus bertambah, bahkan menurut laporan World Health Organization (2009) jumlah kasus positif flu burung di Indonesia adalah yang tertinggi di dunia, yaitu 141 orang, dari jumlah total kasus positif flu burung di dunia 399 orang. Pemerintah Indonesia telah menetapkan bahwa obat untuk penderita flu burung adalah oseltamivir carboxylate (Tamiflu®), akan tetapi terdapat beberapa masalah dari obat ini yaitu, bahan bakunya berasal dari tanaman star anise (Illicium verum) harus diimpor seluruhnya dari Vietnam atau China, harganya mahal, dan terdapat kecenderungan resistensi terhadap oseltamivir. Oleh karena itu perlu secepatnya mencari alternatif sumber bahan baku obat flu burung yang diharapkan tidak saja dapat lebih efektif mengatasi penyakit ini tetapi juga lebih mudah diperoleh dan murah biayanya. Metode penelitian dibagi menjadi dua tahapan, yaitu persiapan ekstrak dan pengujian hambatan virus ke sel. Pembuatan ekstrak meliputi sortasi, pencucian, pengeringan, pengilingan dan ekstrasi. Ekstraksi dilakukan dengan pelarut alkohol 95%. Penentuan kadar komponen kimia dalam ekstrak dilakukan dengan menggunakan metode kromatografi gas-spektrometri massa (KG-SM). Tahap akhir dari penyiapan ekstrak adalah sterilisasi ekstrak menggunakan radiasi, kemudian masing-masing ekstrak sambiloto dan beluntas dibagi menjadi tiga macam konsentrasi, yaitu 10% (μL/ μL), 20%, 30%.
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Judul: Study of Fennel (Foeniculum vulgare Mill.) and Pink and Blue Ginger (Curcuma aeruginosa Roxb.) Ethanol Extracts as Medicinal Alternative against Avian Influenza.
Abstrak: Avian influenza or bird flu is becoming a global issue, especially in Indonesia. The cumulative number of bird flu in Indonesia until February 2009 was 141 people, which was 35,3% from the total of people in the world that infected by bird flu virus. Oseltamivir carboxylate (Tamiflu@), amantadin, and rimantadin had been pledged as drugs of choice for the bird flu. Unfortunately, those drugs becomes very expensive and difficult to find. Moreover, the latest researchs indicated of resistancy to these drugs. Traditional medicine has been used by Indonesian people for many years, but the scientific research concerning to this subject was limited. This study try to evaluate pink and blue ginger (Curcuma aeruginosa Roxb.) and fennel (Foeniculum vulgare Mill.) as alternative medicine against bird flu in in vitro methode. Extracts of Pink and Blue Ginger and fennel were divided into three kind of concentration, which are 10%,20%, and 30% (v/v). The result indicated that temu ireng had strong potency as alternative medicine against bird flu, and concentration 20% was the strongest from the others. Fennel also showed its potency as alternative medicine against bird flu, but less potential than temu ireng. The three kind concentration of adas did not indicate different potency as alternative medicine against bird flu.
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Judul: Approximation of the Median of Poisson Distribution Using the Relation of Poisson-Gamma Distribution
Abstrak: A major drawback of median is that median cannot usually be defined in closed form, even in the cases where their distribution functions are known. This study gives an approximation of the closed form for the median of the Poisson distribution by using the relation of Poisson-Gamma distribution. The approximation uses elementary techniques based on the monotonicity of certain sequences involving tail probabilities of the Poisson distribution and the Central Limit Theorem. Furthermore, a closed form expression for the mean absolute deviation 􀜧|􀜰􀰒 􀵆 􀜯􀝁􀝀􁈺􀜰􀰒􁈻| is also studied. The median is relevant because of the fact that it minimizes the mean absolute deviation of a Poisson random variable (􀜰􀰒􁈻 by considering median as central tendency.
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