Judul: Faktor-Faktor yang Memengaruhi Minat Beli Kosmetik Halal di Kabupaten Bogor
Abstrak: Muslim diwajibkan untuk mengonsumsi produk halal. Salah satu produk halal yang dikonsumsi oleh muslim adalah produk kosmetik. Berdasarkan survei Zap Beauty Index (2020), ditemukan bahwa 49,5 persen konsumen tidak memerhatikan label halal ketika akan membeli kosmetik. Penelitian ini bertujuan menganalisis faktor-faktor yang memengaruhi minat beli kosmetik halal di Kabupaten Bogor dengan mengambil sampel sebanyak 100 responden. Metode penarikan sampel yang digunakan adalah ¬purposive sampling dan dianalisis menggunakan Structural Equation Model-Partial Least Square (SEM-PLS). Hasil penelitian menunjukkan bahwa faktor yang signifikan memengaruhi minat beli masyarakat Kabupaten Bogor untuk membeli kosmetik halal adalah sikap, norma subjektif, kesadaran halal, dan religiusitas., Muslims are required to consume halal products. One of the halal products consumed by muslim is cosmetics. Based on the Zap Beauty Index (2020) survey, it was found that 49.5 percent of consumers did not pay attention to halal labels when buying cosmetics. This study aims to analyze the determinant factors of purchase intention of halal cosmetics in Bogor Regency by taking a sample of 100 respondents. The sampling method used is purposive sampling and analyzed using Structural Equation Model-Partial Least Square (SEM-PLS). The results show that the factors that significantly determine purchase intention in Bogor Regency to buy halal cosmetics are attitude, subjective norm, halal awareness, and religiosity.
Keyword: halal, kosmetik, minat beli, sem-pls

Judul: Faktor-faktor yang Memengaruhi Awareness pada Produk Kosmetik Halal di Wilayah Bogor
Abstrak: Mayoritas muslim di Indonesia telah menyebabkan kebutuhan produk halal semakin meningkat, termasuk kosmetik halal. Kota dan Kabupaten Bogor merupakan daerah yang sangat sangat memperhatikan aspek halal. Tujuan dari penelitian ini yaitu untuk menganalisis faktor-faktor yang memengaruhi awareness pada produk kosmetik halal di Kota, Kabupaten, dan Wilayah Bogor secara keseluruhan. Teknik pengambilan contoh dalam penelitian ini menggunakan tekinik purposive sampling dengan 100 responden di Kota Bogor dan 100 responden di Kabupaten Bogor yang berusia 18 tahun keatas. Metode pengolahan dan analisis data dalam penelitian ini menggunakan analisis deskriptif dan analisis Structural Equation Modeling-Partial Least Square (SEM-PLS). Hasil penelitian menyatakan bahwa faktor-faktor yang memengaruhi awareness pada produk kosmetik halal di Kota, Kabupaten maupun Wilayah Bogor secara keseluruhan adalah halal certification, religious belief, dan halal exposure.
Keyword: awareness, halal certification, halal exposure, kosmetik halal, religious belief

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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