Judul: Perancangan dan Implementasi Container dengan Konsep Swarm dan Metode Ingress Load Balancing Menggunakan Docker
Abstrak: Masjid Alumni IPB ingin mengembangkan suatu sistem yang disebut masjid berbagi. Masjid berbagi merupakan suatu sistem berbasis aplikasi web dan mobile dan terhubung ke cloud. Masjid berbagi dibuat untuk pengelolaan dan berbagi informasi tentang kegiatan masjid-masjid. Semua aplikasi dan informasi disimpan pada server masjid berbagi sehingga server masjid berbagi harus dapat melayani permintaan oleh masjid-masjid. Pada penelitian ini bertujuan untuk perancangan dan implementasi container menggunakan docker dengan menerapkan docker swarm dan load balancing ingress. Penelitian ini dibagi kedalam empat tahap utama yaitu komunikasi (analisis lingkungan), penerapan container, pengujian dan analisis. Pada penelitian dilakukan perbandingan penerapan dengan satu sampai lima container untuk mengetahui pengaruh banyak container dengan respon server, request yang dapat dilayani dan throughput. Hasil penelitian menunjukkan semakin banyak container lebih baik daripada hanya menggunakan satu container karena dapat meningkatkan respon time dan banyak sucess request. Tetapi banyaknya container harus tetap diperhatikan.
Keyword: Docker, Container, Ingress load balancing, Docker swarm

Judul: Containerization of Water Quality Monitoring and Controlling System Web Application Using Docker
Abstrak: Budi daya udang vaname mengalami kenaikan produksi sebesar 250% pada tahun 2024 menjadi sebesar 1.290.00 ton. Kenaikan produksi udang tersebut dapat berpengaruh pada pengelolaan limbah tambak udang. Diperlukan sistem pemantauan dan pengendalian kualitas air untuk membantu pembudi daya dalam mengolah air. Aplikasi web dan mobile digunakan untuk memantau data kualitas air secara langsung yang dikirimkan oleh sensor IoT ke peladen edge computing. Kontainerisasi menggunakan Docker membantu dalam konsistensi dependensi dan konfigurasi untuk deployment. Tahapan analisis kebutuhan, perancangan, implementasi, pengujian, dan evaluasi dilakukan untuk mempermudah deployment. Perancangan kontainerisasi telah berhasil dilakukan dengan membuat konfigurasi file Dockerfile dan Docker Compose yang dibagi untuk lingkungan pengembangan dan lingkungan produksi. Implementasi dilakukan di satu lingkungan pengembangan dan tiga belas lingkungan produksi yang kemudian diuji untuk dipilih spesifikasi yang cocok untuk deployment. Hasilnya, spesifikasi dengan CPU satu core dan memori satu gigabita dengan distribusi sistem operasi Fedora Linux merupakan referensi spesifikasi minimum yang cocok untuk dijadikan peladen deployment aplikasi web., Vaname shrimp farming experienced a 250% increase in production in 2024 to 1,290,00 tons. The increase in shrimp production can affect the management of shrimp pond waste. A water quality monitoring and controlling system is needed to assist farmers in treating water. Web and mobile applications are used to monitor live water quality data sent by IoT sensors to edge computing servers. Containerization using Docker helps in consistency of dependencies and configuration for deployment. Stages of requirement analysis, design, implementation, testing, and evaluation are performed to facilitate deployment. Containerization design has been successfully done by creating Dockerfile and Docker Compose configuration files that are divided for the development environment and production environment. Implementation was carried out in one development environment and thirteen production environments which were then tested to select suitable specifications for deployment. As a result, the specification with one core CPU and one gigabyte memory with Fedora Linux operating system distribution is a suitable reference minimum specification to be used as a web application deployment server.
Keyword: Docker, WQMCS, Docker Compose, Kontainerisasi, Peladen

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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