Judul: Aktivitas anthelmintika ekstrak Daun Miana (Coleus blumei) terhadap Hymenolepis microstoma in vitro
Abstrak: Penelitian ini bertujuan untuk mempelajari aktivitas anthelmintika ekstrak daun miana terhadap Hymenolepis microstoma in vitro. Daun miana dikeringkan dan diekstraksi dengan menggunakan pelarut kloroform dan etanol. Sebanyak 3 ekor cacing dimasukkan ke cawan mikrotitrasi yang telah berisi ekstrak kloroform atau etanol daun miana dengan konsentrasi 10%, 5%, 2.5%, 1%, 0.5%, kontrol negatif (NaCl fisiologis), dan sebagai kontrol positif (praziquantel). Pengujian ini diulang sebanyak tiga kali. Pengamatan dilakukan terhadap waktu paralisis dan kematian cacing pada setengah jam pertama dan dilanjutkan satu jam sekali. Hasil penelitian menunjukkan bahwa ekstrak etanol dan kloroform berbeda nyata (p<0.05). Ekstrak etanol dan kloroform memiliki aktivitas anthelmintika yang kuat. Aktivitas anthelmintika semakin meningkat seiring peningkatan konsentrasi ekstrak. Aktivitas anthelmintika ekstrak etanol lebih kuat dibandingkan dengan kloroform. Konsentrasi (0.5%-10%) pada ekstrak etanol menunjukkan aktivitas anthelmintika yang lebih kuat dibandingkan dengan kontrol positif sedangkan pada ekstrak kloroform lebih lemah dibanding kontrol positif dan etanol.
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Judul: Aktivitas Antifungi Ekstrak Daun Miana (Coleus scutellariodes [L] benth) pada Pertumbuhan Candida albicans Secara In Vitro
Abstrak: Miana (Coleus scuttellariodes [L] Benth) is one of the traditional medicine from family Lamiceae having flavonoids, tannins, saponins, steroids, and triterpenoids compound those can be used as antifungal. The objectives of this research were to examine the antifungal activity of Coleus scuttellariodes [L] Benth leaves extract against C. albicans and to analyze the active compounds in Coleus scuttellariodes [L] Benth leaves extract that has potential as an antifungal against C. albicans. The methods of this research were extraction with aquades, etanol 70%, and acetone, antifungal activity test by agar well diffusion and identification of active compound extract with the best inhibition in antifungal activity with Gas Chromatography-Mass Spectrometry (GC-MS). The result showed that acetone extract 400 mg/mL had the highest inhibition activity with the zone of 4.66 mm included in the low category, meanwhile aquades and etanol 70% extract did not show antifungal activity. Positive control nystatin concentration of 1.028 mg/mL is more effective in inhibiting of C. albicans. Minimum inhibition concentration value of acetone extract was 1.56 mg/mL. Identification of acetone extract with GC-MS result phytol in amount of 41.29%.
Keyword: Coleus scutellariodes, Candida albicans, antifungal

Judul: Implementation of Spatio-Temporal Change Query in Relational Database.
Abstrak: Geographic object changes in various views. Object changes are recorded using a model of static storage. No historical connection between old version data and new version data has been built. For that, a storage model of spatio-temporal queries that can analyze spatio-temporal changes has been developed. The object changes the geometry are grouped according to the taxonomy of Spatio-Temporal Pattern Change. This research has been able to apply the query patterns change including born, expand, merge, contract, split, normal and die. This query based on geometric (area) changes. The implementation of spatio-temporal change queries represents an object changes continuously with easy, change detection is done by comparing two versions of data. Keyword: spatio-temporal change query, spatio-temporal change pattern.
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