Judul: Analisis dan Perancangan Struktur dan Skala Upah Pada Usaha Kecil Sektor Makanan dan Minuman di Kabupaten Bogor
Abstrak: Di tengah pertumbuhan jumlah UMKM yang terus meningkat, diiringi juga dengan turnover intention karyawan dengan alasan kompensasi yang kurang adil. Hal ini terjadi karena belum tersusunnya Struktur dan Skala Upah di UKM tersebut . Peraturan Menteri Ketenagakerjaan Nomor 1 Tahun 2017 juga mewajibkan setiap Usaha memiliki Struktur dan Skala Upah dan akan dikenakan sanksi apabila melanggar. Tujuan penelitian ini ialah 1) Mengidentifikasi penerapan sistem kompensasi yang ada pada Usaha Kecil Kabupaten Bogor, 2) Menganalisis pemberian kompensasi secara internal dan eksternal, 3) Menyusun SSU bagi Usaha Kecil Kabupaten Bogor berdasarkan metode dua titik. Pengumpulan dan pengolahan data dilakukan pada Januari hingga Juli 2024 di 9 Usaha Kecil Kabupaten Bogor. Jenis dan Sumber data penelitian ini ialah data primer dan data sekunder. Metode yang digunakan ialah analisis deskriptif, salary survey, salary mapping dan metode dua titik. Hasil penelitian menunjukkan bahwa setiap Usaha Kecil sudah menggaji karyawan sesuai Struktur dan Skala Upah Rekomendasi karena sudah dalam keadaan inpaid., Amid the growing number of MSMEs, there is also an increase in employee turnover intention due to perceived unfair compensation. This occurs because these SMEs have not yet established a Wage Structure and Scale. The Minister of Manpower Regulation No. 1 of 2017 also requires every business to have a Wage Structure and Scale, with sanctions for non-compliance. The objectives of this study are 1) To identify the implementation of existing compensation systems in Small Businesses in Bogor Regency, 2) To analyze internal and external compensation, 3) To develop a Wage Structure and Scale for Small Businesses in Bogor Regency based on the two-point method. Data collection and processing were conducted from January to June 2024 in 9 Small Businesses in Bogor Regency. The types and sources of data for this research are primary and secondary data. The methods used are descriptive analysis, salary survey, salary mapping, and the two-point method. The results show that each Small Business is already paying employees according to the Recommended Wage Structure and Scale as they are in an inpaid condition.
Keyword: Kompensasi, metode dua titik, usaha kecil, makanan dan minuman

Judul: Analysis and Design of Wage Structure and Scale in
Small Food and Beverage Businesses in Bogor Regency
Abstrak: Di tengah pertumbuhan jumlah UMKM yang terus meningkat, diiringi juga dengan turnover intention karyawan dengan alasan kompensasi yang kurang adil. Hal ini terjadi karena belum tersusunnya Struktur dan Skala Upah di UKM tersebut . Peraturan Menteri Ketenagakerjaan Nomor 1 Tahun 2017 juga mewajibkan setiap Usaha memiliki Struktur dan Skala Upah dan akan dikenakan sanksi apabila melanggar. Tujuan penelitian ini ialah 1) Mengidentifikasi penerapan sistem kompensasi yang ada pada Usaha Kecil Kabupaten Bogor, 2) Menganalisis pemberian kompensasi secara internal dan eksternal, 3) Menyusun SSU bagi Usaha Kecil Kabupaten Bogor berdasarkan metode dua titik. Pengumpulan dan pengolahan data dilakukan pada Januari hingga Juli 2024 di 9 Usaha Kecil Kabupaten Bogor. Jenis dan Sumber data penelitian ini ialah data primer dan data sekunder. Metode yang digunakan ialah analisis deskriptif, salary survey, salary mapping dan metode dua titik. Hasil penelitian menunjukkan bahwa setiap Usaha Kecil sudah menggaji karyawan sesuai Struktur dan Skala Upah Rekomendasi karena sudah dalam keadaan inpaid., Amid the growing number of MSMEs, there is also an increase in employee turnover intention due to perceived unfair compensation. This occurs because these SMEs have not yet established a Wage Structure and Scale. The Minister of Manpower Regulation No. 1 of 2017 also requires every business to have a Wage Structure and Scale, with sanctions for non-compliance. The objectives of this study are 1) To identify the implementation of existing compensation systems in Small Businesses in Bogor Regency, 2) To analyze internal and external compensation, 3) To develop a Wage Structure and Scale for Small Businesses in Bogor Regency based on the two-point method. Data collection and processing were conducted from January to June 2024 in 9 Small Businesses in Bogor Regency. The types and sources of data for this research are primary and secondary data. The methods used are descriptive analysis, salary survey, salary mapping, and the two-point method. The results show that each Small Business is already paying employees according to the Recommended Wage Structure and Scale as they are in an inpaid condition.
Keyword: Kompensasi, metode dua titik, usaha kecil, makanan dan minuman

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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