Judul: Distribusi Virus Dengue (Denv) Dengan Teknik Imunohistokimia Di Jaringan Beruk (Macaca Nemestrina) Pasca Infeksi Virus Dengue Tipe 3 (Denv-3)
Abstrak: Satwa primata bukan manusia (nonhuman primate) berperan sebagai hewan model yang sangat diperlukan di penelitian biomedis untuk mempelajari berbagai masalah kesehatan manusia, penyakit dan gangguan kesehatan, terapi, dan strategi pencegahan. Dalam penelitian ini, kami menggunakan beruk atau pig-tailed macaque (Macaca nemestrina) sebagai hewan eksperimental untuk mempelajari infeksi virus Dengue tipe 3 (DENV-3). Kami melakukan evaluasi mengenai distribusi dan replikasi DENV-3 pada seluruh jaringan yang dikoleksi menggunakan teknik imunohistokimia setelah infeksi primer untuk melokalisir protein virus. Perubahan makroskopis secara nyata tidak tampak pada seluruh beruk yang dianalisis, namun perubahan mikroskopis pada pemeriksaan histopatologi terlihat dengan derajat keparahan bervariasi pada berbagai jaringan: hati, lambung, limpa dan limfonodus. Protein-protein virus tersebut terlihat pada sel-sel limfoid yang reaktif pada limpa, timus, limfonodus aksilaris, limfonodus inguinalis, limfonodus mesenterika dan limfonodus submandibularis. Secara umum, bukti keberadaan protein virus pada berbagai jaringan setelah infeksi DENV-3 mengungkapkan bahwa M. nemestrina rentan terhadap infeksi dan dapat menjadi alternatif hewan model yang baik untuk mengevaluasi replikasi DENV di jaringan.
Keyword: DENV-3, Macaca nemestrina, imunohistokimia

Judul: Profil Antibodi IgM dan IgG pada Beruk (Macaca nemestrina) setelah Diinfeksi Virus Dengue Serotipe-3 (DEN-3) melalui Rute Subkutan
Abstrak: This study was to compare the immune response in pig-tailed macaques (Macaca nemestrina) induced by the dengue virus serotype-3 (DEN-3) via subcutaneous route. There are 3 groups of animal in the study. Group 1 (n=6) were infected by DEN-3 at low dose level of 104 PFU/ml, group 2 (n=6) were infected by DEN-3 at high dose level of 107-108 PFU/ml, and group 3 (n=4) were infected by PBS; all groups were innoculated by subcutaneous route. The blood samples were collected using venesectio method in femoralis vein on day 0 prior the infection followed by day 1 until day 13 post infection. IgM and IgG antibodies were detected by Indirect Enzym Linked Immunosorbent Assay (ELISA). Dengue virus induced humoral immune respons producing antibodies. The antibody profile analyses showed different by individual animals, but similar in general. The IgM titer started to increase on day 4 or day 5 post infection and reached the peak on day 9 post infection and decline afterward; The IgG titer started to increase on day 7 or 8 post infection. In general the increase of IgM titer started earlier than the IgG and the titer of IgM was higher than the IgG.
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Judul: Enhancement of photon absorbtion on BaxSr1-xTiO3 thin films semiconductor using photonic crystals.
Abstrak: In this research, has been conducted BaxSr1-xTiO3 (BST) thin films manufacturing for mole fraction x = 0.25, 0.35, 0.45, and 0.55; and concentration of 1 molar using chemical solution depositon (CSD) method. The materials, which are used in this research, are barium acetate [Ba(CH3COO)2, 99%], strontium acetate [Sr(CH3COO)2, 99%], titanium isopropoxide [Ti(C12O4H28), 97.999%], gallium trioxide [Ga2O3], 2-methoxyethanol [H3COOCH2CH2OH, 99%] and 1 x 1 cm of transparent conductive oxide (TCO) glass as substrate. Two BST thin films are made that for BST thin films which are doped by 10% galium (BGST) as p-type layer and pure BST solution as n-type. BST solution is made by reacting barium acetate [Ba(CH3COO)2, 99%], strontium acetate [Sr(CH3COO)2, 99%] and titanium isopropoxide [Ti(C12O4H28)] into 2-methoxyethanol solvent [H3COOCH2CH2OH, 99%] in accordance with mass gram for each x value. While, BGST solution is made in the same way as BST solution, plus adding gallium at 10% of the mass of BST. Once all materials are reacted, then vibrated using ultrasonic for 90 minutes, and followed by coating BGST / BST on the TCO substrate. Once the layer is formed, then annealed for 15 hours at temperature of 500 °C with increasing rate of 1.67 oC/minute. Characterizations of BST thin films with or without photonic crystals include the absorbance and transmittance in the visible light spectrum, as well as the electrical photoconductivity characterizations. From BST thin films without photonic crystals indicate that our thin films have light absorption area on almost the entire range of the visible light spectrum even to the infrared range with absorption value over than 67.6%, in addition, it can be seen that the maximum absorbance of BST thin films for all mole fractions lie in blue to green light spectrum region, 457 nm ≤ λ ≤ 570 nm and the minimum in yellow to red light spectrum region, 570 nm ≤ λ ≤ 678 nm. The largest absorbance is found at x = 0.25 with average absorbance value of 92.04% and maximum and minimum absorbance peaks at wavelength of 500.89 and 657.72 nm, respectively. At x = 0.35, average absorbance value decreased to 83.55% with maximum and minimum peaks at 505.73 and 613.68 nm, respectively. Then increased to 91.16% at x = 0.45 with maximum and minimum peaks at 506.04 and 618.56 nm, respectively. At x = 0.55, average absorbance value decreased to 80.12% with maximum and minimum peaks at 507.85 and 608.79 nm, respectively. Moreover, it can be seen that the addition of barium mole fraction leads to wider maximum absorbance or minimum transmittance peaks and narrower minimum absorbance or maximum transmittance peaks in the same range of the green and blue & red light spectrums, respectively. BST thin films with photonic crystals show increasing in absorption for all x values in the range of 3.04 into 13.33%. At x = 0.25, average absorbance percentage increased 3.96% from 92.4 into 95.68%, for x = 0.35 average percentage increased 7.07% into 89.45 from 83.55%. Furthermore, average absorbance of BST thin films at x = 0.45 increased 3.04% from 91.16 into 93.93% and x = 0.55 has
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