Judul: Studi Kasus di Jakarta Timur
Abstrak: Makanan sangat besar pengaruhnya terhadap keadaan gizi seseorang khususnya pada usia bayi sampai balita karena kekurangan gizi pada masa ini dapat berpengaruh buruk terhadap pertumbuhan fisik dan mental tahapan selanjutnya. Kebutuhan akan makanan bayi siap saji khususnya bubur bayi semakin meningkat sejalan dengan perkembangan jumlah bayi dan balita dan peningkatan angkatan kerja wanita. Meningkatnya potensi pasar ini diikuti dengan meningkatnya kompetisi antar produsen produk makanan bayi yang terlihat dari munculnya berbagai merek dan jenis makanan bayi di pasaran.
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Judul: Studi Kasus : Kotamadya Bogor
Abstrak: Peningkatan jumlab permintaan terhadap pangan di Indonesia mengikuti laju peningkatan jumlah penduduk yang disebabkan oleh laju kelahirannya yang sangat tinggi. Hal inilah yang mendorong berkembangnya industri makanan bayi jadi atau bubur bayi kemasan yang merupakan salah satu jenis makanan bayi hasil dari teknologi, sehingga berbagai macam jenis, merek, dan rasa bubur bayi kemasan dijual di pasaran. Perkembangan industri bubur bayi kemasan tersebut menciptakan pesaingan yang ketat diantara produsen-produsen bubur bayi kemasan. Di tengah-tengah persaingan yang ketat tersebut, perilaku konsumen bubur bayi kemasan, dalam hal ini ibu rumah tangga, merupakan suatu aspek penting yang harus menjadi orientasi perusahaan dalam usahanya mempertahankan pasar bahkan memperluas pangsa pasarnya.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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