Judul: Kajian Morfologi Proses Persembuhan Kerusakan Segmental Pada Tulang Domba Yang Diimplan Dengan Komposit Hidroksiapatit-Kitosan (HA-K)
Abstrak: This research was aimed to study the morphology of healing process on sheep’s bone implanted with hydroxyapatite-chitosan (HA-C) composite. This research would also present information about the potency of HA-C composite as synthetic bone graft biomaterial or bone implant. Three local sheeps were used in this study. HA-C composite was implanted on the medial of the left tibia bone while the same part of right tibia was treated as control without implant. All implant were harvested at 30, 60, and 90 days post-operation. The observation parameters were the condition, shape, and degradation degree of the implant, bonding between implant and host bone, new bone ingrowth into the implant, and signs of inflammation reaction around the implant. The result showed that the healing process on control bone was faster than those of the implanted bone. As far as 90 days observation in this present study was concerned, HA-C implant did not show characteristics for biodegradability, bioresorbability, osteoconductivity, and bioactivity. However, it showed biocompatibility properties for host body. It is suggested that the implant used in this study is more suitable to be developed as synthetic bone graft biomaterial for application on large defects with healing time longer than 90 days.
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Judul: Kajian Morfologi Proses Persembuhan Kerusakan Segmental Pada Tulang Domba Yang Diimplan Dengan Komposit Hidroksiapatit-Trikalsium Fosfat (HA-TKF)
Abstrak: This study was aimed to evaluate in vivo osteogenesis potency of bones implanted with graft of hydroxyapatite-tricalcium phosphate (HA-TCP) composite. This study also observed the potential use of HA-TCP as bone substitution material. Three local sheeps were used in this study. The implant was inserted under aseptic surgery on the proximal medial of the left tibia bone and as control the proximal medial of the right tibia bone was drilled without implant. Bones were harvested after 30, 60, and 90 days post-surgery and observed macroscopic and microscopically. The parameters of observation were the condition, shape and degradation degree of the implant, bonding between implant and host bone, new bone growth into the implant and signs of inflammation reaction around the implant. The result showed that the healing process on control bone was faster than those of the implanted bone. The bone implant had been already degradated in treated group of day 30 post-surgery. HA-TCP bone implant shown some signs for its biocompatibility, biodegradability, bioresorbability and osteoconductivity properties. Therefore, it is suggested that HA-TCP implant might be used as bone substitution in the bone lesions with approximately 30 days of recovery.
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Judul: Pemilihan Lokasi Pemantauan Kualitas Udara di Jakarta berdasar Sebaran Konsentrasi Pencemar Maksimum Luaran Model WRF-Chem
Abstrak: Jakarta dikategorikan sebagai megacities yang tidak bisa dilepaskan dari perkembangan sektor industri dan transportasi. Hal ini berdampak pada pelepasan emisi pencemar ke udara berupa PM10 dan NO2 dan berpotensi terjadinya pencemaran udara. Pencemaran udara dapat mengganggu kesehatan yang fatal bagi masyarakat, sehingga diperlukan upaya antisipasi melalui pemantauan kualitas udara berkelanjutan. Jumlah stasiun pemantau yang ada belum representatif mewakili seluruh Jakarta. Oleh karena itu, penelitian ini bertujuan untuk menganalisis sebaran pencemar PM10 dan NO2 di Jakarta, serta mengidentifikasi lokasi dengan konsentrasi pencemar maksimum untuk dijadikan lokasi pemantauan kualitas udara ambien secara kontinu di Jakarta. Pemodelan mengenai dispersi pencemar menjadi pilihan untuk menganalisis kualitas udara secara spasial dari waktu ke waktu, sehingga dapat membantu menganalisis lokasi-lokasi yang berpotensi terpapar konsentrasi pencemar maksimum. Pemodelan yang dapat digunakan adalah Weather Research Forecasting- Chemistry (WRF-Chem). Berdasar hasil pemodelan menunjukkan bahwa pola sebaran PM10 dan NO2 mengikuti mekanisme pola angin darat dan laut. Pola sebaran pencemar berdasar luaran model menunjukkan daerah Jakarta Selatan merupakan wilayah yang sering terkena paparan maksimum oleh pencemar NO2, sedangkan wilayah yang sering terkena paparan maksimum pencemar PM10 adalah daerah Jakarta Utara. Selama periode pemodelan (672 jam), yaitu pada bulan Februari dan Agustus (336 jam) tahun 2010 serta periode Agustus tahun 2011 dan 2015 dengan masing-masing running selama 168 jam diperoleh 17 lokasi yang berpotensi terpapar konsentrasi pencemar baik PM10 maupun NO2. Lokasi tersebut yaitu Pantai Indah Kapuk (PIK), Setu Babakan, Bintaro, Penjaringan, Cilangkap, Cilandak, Pasar Rebo, Ancol, Cengkareng, Pesanggrahan, Cilincing, Kembangan, Banjir Kanal Timur (BKT), Ragunan, Pramuka, Taman Mini Indonesia Indah (TMII) dan Pondok Kelapa.
Keyword: dispersi pencemar, Jakarta, kualitas udara, stasiun pemantau, WRFChem