Judul: Analisis Terhadap Data Survei Balita Indonesia Oleh Perusahaan Fast Moving Consumer Goods
Abstrak: From the survey of 4377 Indonesian toddlers, there are about 19.63% severely malnourished and moderately malnourished, 32.75% have abnormal height, 10.28% have abnormal weight, 54.97% live in poor housing and sanitation, 66.96% live in unhealthy environment, and 52.64% have family with middle-level economy. Severely malnourished children has a very thin to thin weight characteristics. Moderately malnourished children is thin to normal, has a very short stature, low level of health, and low-level economy. Parental education has an important role in health and condition of living environment. The lack of economic families is not always followed by malnourished children. But, family with high-level economy is followed by overnourished children. The more healthy living environment of toddler, the better nutritional status. Region of Kalimatan and eastern Indonesia seems to be priority in reduction of malnourished children. Parameters of geographic, economic, sanitation and housing, and neighborhoods do not seem good enough in describing the nutritional status of toddler. The better parameters in describing the nutritional status are household expenditure, the percentage of expenditure for toodler, the number and the order of children in the family, home ownership status, and spacious home inhabited. In addition, the design of survey area should be made more scientific.
Keyword: nutritional status, multiple correspondences, toddler characteristic

Judul: The Relationship Food Consumption, Parenting Practice and Food Security with The Nutritional Status of Toddlers in Cianjur
Abstrak: Nutritional problems are a major problem in developing countries like Indonesia. Nutritional problems will impact the low quality of human resources (Bappenas RI 2020). WHO data states that there are 149.2 million children under five experiencing stunting and 45.5 million children experiencing wasting (WHO et al. 2021). The Indonesian Nutrition Status Study (SSGI) stated that the prevalence of wasting was 7.1%, underweight was 17.0%, and stunting was still very high at 24.4% (Ministry of Health RI 2021). One of the provinces with a high prevalence of nutritional problems in toddlers is West Java, where wasting in West Java 5.3%, while underweight 15.0% and stunting 24.5%. In Cianjur Regency, the prevalence of wasting was 2.9%, underweight was 14.1%, and the prevalence of stunting was quite high at 33.7%. In overcoming the problem of nutrition, Indonesia launched a program known as the National Movement to Accelerate Nutrition Improvement in the framework of the First Thousand Lives (1000 HPK Movement). Presidential Regulation number 42 of 2013 states that specific and sensitive interventions are needed to tackle the problem of malnutrition (Ministry of Health Regulation 2013). Even though there have been many programs by the government, until now, nutritional problems such as being underweight, wasting and stunting still have a fairly high prevalence. Many studies have been conducted regarding the factors that influence nutritional problems, but each study in a different location will produce different results. In theory, food safety and parenting style for toddlers will affect food consumption, which will ultimately have an impact on the nutritional status of toddlers. Based on this, researchers are interested in analysing the relationship between parenting, parenting food consumption, and food security with nutritional status in toddlers which, in theory, is a factor in the occurrence of nutritional problems. This study uses some data from a study entitled "Analysis of Household Socioeconomic and Gender-Based Determinants of Food and Nutrition Security in Rural and Urban Areas: A Study in West Java, East Kalimantan, Central Sulawesi and West Nusa Tenggara". The research was conducted in May-January 2023 in Cianjur Regency, West Java Province. This research has received Ethical Approval from the Research Ethics Commission involving Humans IPB University with No.78680/IT3.KEPMSM-IPB/SK/2022. The total subjects in this study were 91 toddlers aged 24-59 months. Respondents in this study were mothers of toddlers aged 24-59 months in Cianjur Regency. The inclusion criteria in the study were that the respondents were mothers of children under five aged 24-59 months in Cianjur Regency and were willing and ready to participate in this study using Indonesian. The data used in this research is primary data. Researchers collected the data through interviews using questionnaires and direct measurements. Data on subject characteristics collected through a questionnaire included age, gender, mother's education, mother's occupation, mother's level of knowledge related to nutrition, family socio-economic status, food security, parenting style and history of infectious diseases. Data on consumption patterns, including nutrient intake and food quality, were collected through questionnaires, 24-hour recall, Individual Dietary Diversity Score (IDDS), and Household Dietary Diversity Questionnaire (HDDS). Data related to food security consisting of food insecurity was
Keyword: food security, food consumption, nutritional status, toddlers, parenting practice.

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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