Judul: Analisis Perbedaan Orientasi Pertumbuhan pada Usaha Kecil di Bogor
Abstrak: Small business has an important role in national’s economy system. On the other side, some of the small businesses did not exist for a long term because of the ownermanager lack of management ability. Therefore, research regarding small business growth is needed so the owner-manager can focused on the factors that influence the growth of small business. This research is aimed to identify the differencing factors between the growth oriented and the less growth oriented small business, and the small business managerial key factors on agribusiness sector which is growth oriented based on six key dimensions of small business high performance. Direct interview was conducted to the owner-manager of small businesses in Bogor, with purposive sampling method. Discriminant analysis method is used to identify the difference between of growth oriented and less growth oriented small business, meanwhile stepwise discriminant analysis is used to find the difference key factor between the two groups. The result showed that there were seven differentiating factors between the growth oriented and less growth oriented small business, which are mission, vision, strategies, resource supply assurance, customer commitment development, quality, alteration leadership ability, and execution. Meanwhile the small business managerial key factors which is growth oriented is the mission factor.
Keyword: small business growth, owner-manager, entrepreneurship, discriminant

Judul: The Effect of Social Capital and Entrepreneurial Orientation on Business Performance of Women Entrepreneurs in Bogor City
Abstrak: Transformasi semangat berwirausaha saat ini tidak hanya didominasi oleh laki-laki, melainkan juga oleh perempuan. Pemberdayaan perempuan wirausaha menjadi salah satu indikator terwujudnya pembangunan berkelanjutan di Indonesia. Keberhasilan perempuan wirausaha ditentukan oleh berbagai faktor, antara lain modal sosial dan orientasi kewirausahaan. Tujuan dari penelitian ini yaitu untuk menganalisis pengaruh modal sosial dan orientasi kewirausahaan terhadap kinerja usaha perempuan wirausaha di Kota Bogor. Penentuan sampel pada penelitian ini dilakukan dengan menggunakan metode convenience sampling. Data yang digunakan berupa data primer melalui penyebaran kuesioner pada perempuan wirausaha dengan jumlah responden sebanyak 136 orang. Data yang diperoleh dianalisis menggunakan analisis deskriptif dan analisis PLS-SEM menggunakan perangkat lunak SmartPLS 3. Hasil dari penelitian ini menunjukkan bahwa modal sosial berpengaruh positif dan signifikan terhadap orientasi kewirausahaan, orientasi kewirausahaan berpengaruh positif dan signifikan terhadap kinerja usaha, dan modal sosial tidak berpengaruh signifikan terhadap kinerja usaha. Namun pengaruh modal sosial jika dimediasi oleh orientasi kewirausahaan menjadi positif dan signifikan terhadap kinerja usaha pada perempuan wirausaha di Kota Bogor., The transformation of the entrepreneurial spirit is currently not only dominated by men but also by women. The empowerment of women entrepreneurs is one of the indicators of the realization of sustainable development in Indonesia. The success of women entrepreneurs is determined by various factors, including social capital and entrepreneurial orientation. The purpose of this study is to analyze the influence of social capital and entrepreneurial orientation on the business performance of women entrepreneurs in Bogor City. The sample determination in this study was carried out using the convenience sampling method. The data used are primary data through distributing questionnaires to women entrepreneurs with a total of 136 respondents. The data obtained were analyzed using descriptive analysis and PLS-SEM analysis using SmartPLS 3 software. The results of this study indicate that social capital has a positive and significant effect on entrepreneurial orientation, entrepreneurial orientation has a positive and significant effect on business performance, and social capital has no significant effect on business performance. However, the effect of social capital, if mediated by entrepreneurial orientation, becomes positive and significant on the business performance of women entrepreneurs in Bogor City.
Keyword: agribusiness actors, small and medium enterprises, women empowerment

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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