Judul: Penyelesaian Split Delivery Vehicle Routing Problem Menggunakan Algoritme Tabu Search.
Abstrak: Split Delivery Vehicle Routing Problems (SDVRP) merupakan masalah penentuan rute pendistribusian barang ke para pelanggan yang dimulai dan diakhiri di suatu depot. Setiap pelanggan dapat dikunjungi lebih dari satu kali. Model SDVRP merupakan kasus NP-Hard Problem yang dapat diselesaikan menggunakan metode eksak, heuristic maupun meta-heuristic. Pada karya ilmiah ini, SDVRP diselesaikan menggunakan metode eksak Integer Linear Programming (ILP) dan metode meta-heuristic Tabu Search 2-opt. Hasil uji coba memperlihatkan bahwa waktu eksekusi menggunakan metode meta-heuristic jauh lebih cepat dibandingkan dengan metode eksak. Akan tetapi, metode meta-heuristic masih menghasilkan selisih jarak yang relatif besar dibanding metode eksak.
Keyword: 2-opt, SDVRP, Tabu Search, 2-opt, SDVRP, Tabu Search

Judul: Penyelesaian Vehicle Routing Problem with Simultaneous Pickup and Delivery Service Menggunakan Algoritme Tabu Search
Abstrak: Vehicle Routing Problems with Simultaneous Pick-up and Delivery (VRPSPD) are the variation of Vehicle Routing Problems (VRP). VRPSPD is a problem to determine the route of vehicle to pick-up and delivery the product at the same time. The goal of VRPSPD is either to minimize the mileage or the cost of shipping the product. In this paper, the VRPSPD problem will be solved by using a heuristic method, namely Tabu search algorithm. Tabu search algorithm is a mathematical optimization method that guides the search for solutions iteratively by providing taboo status to the existing solution. It uses two memory structures that have different functions. It consists several stages that underlie each step in the algorithm, namely the determination of the initial solution, the search of the neighborhood solution, the use of the memory structures, and the termination of the algorithm. The application of VRPSPD is ilustrated in establishing the minimum distance route of drinking water product delivery.
Keyword: VRPSPD, VRP, tabu search, pick-up and delivery, heuristic methods

Judul: Durability of Specific Immunoglobulin (Ig) Y Againts Influenza and Covid-19 in Sunscreen
Abstrak: The benefit of specific immunoglobulin Y (Ig Y) as an active ingredient in personal care products such as sunscreen has not been properly studied. Our study aims to evaluate the reliability of specific IgY against influenza and the COVID-19 virus in a sample sunscreen product. Specific IgY influenza and COVID-19 viruses were inserted in the sample sunscreen at two concentrations of 0.1% and 0.25%. Three treatments were observed: control (C) sunscreen without IgY, treatment 1 (T1) sunscreen with 0.1% IgY, and treatment 2 (T2) sunscreen with 0.25% IgY. Organoleptic observations were carried out to monitor changes in aroma, color, and texture, and sunscreen sampling was done every week for 6 weeks. The durability of IgY was evaluated using an enzyme-linked immunosorbent assay (ELISA) and a neutralization assay. Organoleptic observation from weeks 1 to 6 showed consistency in its aroma, color, and texture. Enzyme-linked immunosorbent assay and neutralization assay (NA) results of the T1 and T2 groups showed negative results except for sample T1 at week 5, which showed a positive result in the Influenza A ELISA. Based on the results, it seems that IgY concentrations of 0.1% or 0.25% were not optimal. However, this negative result might be due to low concentration of the IgY and the presence of beeswax, which inhibits IgY and causes it to dissolve in distilled water, thus preventing it from being detected in the assay.
Keyword: Immunoglobulin Y, Sunscreen, Influenza, COVID-19, Biological Activity