Judul: The Potency of Ciplukan Leaf Extract (Physalis angulata L.) to Improve Kidney Function
Abstrak: Gagal ginjal merupakan penyakit tidak menular namun dapat mengancam nyawa manusia. Penyakit ini dapat dialami dari berbagai macam usia mulai dari anak-anak hingga lansia. Salah satu tanaman yang biasanya dijadikan sebagai obat herbal ialah tanaman ciplukan (Physalis angulata L.). Penelitian ini bertujuan untuk mengetahui potensi dari daun tanaman ciplukan dalam memperbaiki fungsi ginjal. Penelitian ini dilakukan di Kampus IPB Dramaga, IPB University, Bogor, Indonesia. Tikus putih digunakan sebanyak 24 ekor dan dibagi menjadi 8 kelompok. P1: normal, P2: ciplukan dosis 150 mg/kg BB 14 hari, P3: ciplukan 300 mg/kg BB 14 hari, P4: etilen glikol 14 hari, P5: etilen glikol 14 hari dan ciplukan dosis 150 mg/kg BB 14 hari, P6: etilen glikol 14 hari dan ciplukan dosis 300 mg/kg BB 14 hari, P7: etilen glikol dan ciplukan dosis 150 mg/kg BB 14 hari, dan P8: etilen glikol dan ciplukan dosis 300 mg/kg BB 14 hari. Parameter yang diukur adalah bobot badan, kadar ureum, kadar kreatinin, dan histologi ginjal tikus. Data dianalisa dengan analisis sidik ragam ANOVA. Pemberian etilen glikol dan ekstrak ciplukan dosis 300 mg/kg BB secara bersamaan mampu menormalkan kadar ureum dalam darah. Pemberian ekstrak ciplukan setelah diinduksi etilen glikol selama 14 hari (P5 dan P6) tidak mampu mengembalikan kadar ureum pada keadaan normal. Analisis statistic taraf P > (0,05) menunjukkan bahwa hasil tidak berbeda nyata pada kadar kreatinin. Berdasarkan hasil histologi menunjukkan adanya perbaikan pada glomerulus ginjal pada kelompok P8 yakni kelompok pemberian etilen glikol dan ekstrak ciplukan dosis 300 mg/kg BB yang diberikan secara bersamaan dalam 14 hari. Ekstrak tanaman ciplukan juga memiliki kandungan flavonoid yang berpotensi mengatasi masalah pada ginjal ketika diinduksi zat nefrotoksik seperti etilen glikol.
Keyword: Ciplukan (Physalis angulata L.), creatinine, ethylene glycol, kidney, ureum

Judul: Aktivitas Ekstrak Daun Alpukat Terhadap Perbaikan Ginjal Tikus Akibat Induksi Etilen Glikol
Abstrak: Based on data from WHO been 80% of world population has been used plant extract as a medicine. The objective of this research was to study the histopathological lesions of rat kidneys induced by ethylene glycol and treated by ethanol extract of avocado leaves. This study is a continuation of Adha’s experiment (2009) with the experimental design as follows: 20 male rats were divided into four groups, negative control group (KN) who were given only distilled water, positive control group (KP), which provided adlibitum inducer, the first treatment group (E100) is given inducer and avocado leaves ethanol extract dose of 100 mg/kg BB, and the second treatment groups were given inducer and avocado leaves ethanol extract dose of 300 mg / kg BW. Treatment was given for 10 days, at day-11 rats euthanized, and kidney organs were taken for histopathology and stained with Hematoxylin-Eosin. The histopathological study showed edema, protein deposition, hyaline droplets and tubular necrosis. Statistical analysis showed that administration of ethanol extract of avocado leaves could not reduce the incidence of glomerular edema, hyaline droplet and protein deposition of tubules, but it can significantly inhibit the formation of tubular necrotic. Ethanol extract of avocado leaves contain flavonoids that work as antioxidants and diureticum that can inhibit the formation of tubular necrotic.
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Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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