Judul: The Impact of Smartphones on child Marriages in Rural Areas (Case: Lubuk Pabrik Village, Lubuk Besar District, Bangka Tengah Regency, Bangka Belitung Islands)
Abstrak: Penelitian tentang penggunaan ponsel pintar di kalangan anak perempuan pedesaan menghasilkan temuan yang kontradiktif. Di satu sisi, ponsel pintar memiliki manfaat yang positif bagi perempuan. Di sisi lain, ponsel pintar sering digunakan untuk mengakses konteks dewasa dan mempermudah berkomunikasi dengan lawan jenis tanpa sepengetahuan orang tua. Hal ini mengakibatkan meningkatnya pergaulan bebas di antara anak perempuan, seks di luar nikah, dan kehamilan yang tidak diinginkan. Penelitian ini mengkaji pengaruh teknologi ponsel pintar berbasis Android terhadap perkawinan anak perempuan di pedesaan. Berlokasi di Desa Lubuk Pabrik di Provinsi Bangka Belitung, penelitian ini menggunakan mixed-method, kombinasi pengumpulan data kualitatif dan kuantitatif. Analisis regresi logit menunjukkan adanya satu variabel independen yang memiliki pengaruh signifikan terhadap perkawinan anak perempuan di pedesaan yakni ragam penggunaan aplikasi., Research on the use of smartphones among rural children often has contradictory findings. On the one hand, smartphones have positive benefits for children. On the other hand, smartphones are often used to access adult contexts and make it easier to communicate with the opposite sex without parents knowing. This has increased promiscuity among girls, extramarital sex, and unwanted pregnancies. This study examines the effect of Android-based smartphone technology on the early marriage of children in rural areas. Located in Lubuk Besar Village in Bangka Belitung Province, this research uses a mixed-method, a combination of qualitative and quantitative data collection. Logit regression analysis shows that one independent variable significantly influences marriage of children in rural areas, variety of application usage.
Keyword: Android, child marriage, rural, smartphone, women

Judul: Hubungan Tingkat Penggunaan Smartphone Pada Remaja Dengan Interaksi Dalam Keluarga (Kasus Remaja Di Kelurahan Mulyaharja, Kecamatan Bogor Selatan, Kota Bogor)
Abstrak: Pada zaman modern seperti sekarang ini banyak yang bergantung pada kecanggihan teknologi media, salah satunya dengan memanfaatkan smartphone seperti yang digunakan oleh remaja. Banyak remaja yang terpengaruh oleh kecanggihan smartphone, sehingga penggunaan smartphone memberikan perubahan terhadap pola interaksi antara remaja dengan orang tua. Pada saat proses komunikasi berlangsung, gangguan yang membuat perhatian remaja menjadi teralih saat diajak berkomunikasi secara tatap muka atau sering terjadi miscommunication akibat keseruan dengan smartphone mereka masing-masing. Penelitian ini menganalisis keterkaitan antara hubungan tingkat penggunaan smartphone pada remaja dengan interaksi di keluarga. Penelitian dilakukan dengan menggunakan pendekatan kuantitatif yang didukung oleh data kualitatif dan menggunakan metode teknik accidental sampling untuk penarikan sampel. Hasil penelitian menunjukkan bahwa tidak terdapat hubungan yang signifikan antara tingkat penggunaan smartphone pada remaja dengan interaksi di keluarga.
Keyword: Interaksi keluarga, remaja, smartphone

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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