Judul: Pengaruh Jenis Anyaman dan Perekat Terhadap Kualitas Sifat Fisis dan Mekanis Bambu Lapis dari Bambu Andong (Gigantochloa pseudoarundinaceae (Steudel)Widjaja))
Abstrak: This research aims to determine the effect of wove and adhesive type on the quality of woven bamboo plywood from andong with the use of dipping methods. Bamboo plywood bonded using MDI (Methylen Diphenyl Isocyanate) and PVAC (Polyvinyl Acetate). Woven bamboo was soaked in diluted adhesive. It was ensured that the adhesive spread equally on the bamboo’s surfaces (including inner bark strip and outer strip). Results show that in treatment, moisture content, modulus of elasticity (MOE), shrinkage and bonding strength did not have effect in improving the properties of bamboo plywood whereas in treatment density, modulus of rupture (MOR) and thickness swelling affected in improving the properties of bamboo plywood made from bamboo andong. The usage of PVAc did not improve physicals and mechanical properties of bamboo plywood, and did not meet ISO (SNI) 01-5008.2-2000 standard. The usage MDI did not improve bamboo plywood’s quality and its MOE and MOR did not meet the standard; moreover, its moisture content, density, and bonding strength did meet the the ISO (SNI) 01-5008.2-2000 standard
Keyword: woven bamboo., physicals and mechanical properties, PVAc, MDI, bamboo plywood

Judul: Karakteristik Bambu Lapis Menggunakan Anyaman Kajang dari Bambu Andong (Gigantochloa pseudoarundinaceae)
Abstrak: Wood production from forests is decreasing. In other side, the needs on wood as raw material for wood processing industries indicate an inclination to increase. As a consequence, wood supply is getting lower and the price of raw material is increasing. Hence, an effort is needed to produce alternative materials as wood substitution to ensure the sustainability of wood-based industries. The objective of this research was to analyze the influence of adhesive types, composition of width and thickness of bamboo’s strip to the physical and mechanical properties of ply bamboo. Bamboo was used in kajang bamboo mate type with different thickness of 0.5 mm and 1 mm, and different width of 1 cm and 2 cm. The internal bonding and modulus of elasticity (MOE) were not in accordance with SNI 01-5008.2-2000 with the values of less than 7 kg/cm2 dan 80 000 kg/cm2, respectively. Modulus of Rupture (MOR) and physical properties including moisture content and density fulfilled the SNI 01-5008.2-2000 standard which were less than 320 kg/cm2 for MOR and 14% for moisture content. Plybamboos in all combinations of width and thickness using epoxy were better than plybamboo which used PVAc as adhesive. The damage testing of ply bamboo using epoxy was 20.10%-35.58%. Plybamboo using thickness of 8 mm, width of 2 cm, and glued together with epoxy had better physical and mechanical properties compared with other plybamboos.
Keyword: PVAc, plybamboo, epoxy, andong bamboo

Judul: Prediction of T-Cell Epitope Candidate Targeting Conserved-KRAS for Cancer Vaccine using Reverse Vaccinology Approach
Abstrak: Kanker merupakan penyebab kematian kedua terbesar di dunia. Sebanyak 9.6 juta kematian manusia di dunia disebabkan oleh kanker. Kurang lebih sepertiga penderita kanker mengalami mutasi gen KRAS. Mutasi gen KRAS banyak terjadi pada kanker pankreas (90%), kanker kolon (30-40%), dan kanker paru (15-25%). Pendekatan reverse vaccinology dapat mempermudah pengembangan vaksin penyakit yang sebelumnya sulit dan tidak mungkin diproduksi. Penelitian ini bertujuan untuk merancang kandidat epitop sel-T dengan target conserved-KRAS sebagai imunoterapi kanker. KSFEDIHHY merupakan kandidat epitop terbaik yang dihasilkan dari rangkaian penelitian yang dilakukan. Kandidat epitop ini memiliki skor imunogenisitas yang baik, diprediksi dapat berikatan dengan banyak supertipe HLA, bersifat non-alergen dan non-toksik. KSFEDIHHY dapat berikatan dengan HLA B*57:01 dengan affinitas -7.8 kkal/mol. Prediksi ikatan antara peptida dan HLA yang telah dilakukan baik berdasarkan sekuens maupun berdasarkan struktur ini menunjukkan KSFEDIHHY potensial untuk dikembangkan sebagai kandidat epitop untuk vaksin kanker., Cancer is the second cause of death in the world. There are 9.6 million deaths caused by cancer. Approximately one third of cancer patients have the KRAS gene mutation. KRAS gene mutations occur mostly in pancreatic cancer (90%), colon cancer (30-40%), and lung cancer (15-25%). The reverse vaccinology approach can ease the difficulties and impossiblities to produce vaccine. This study aims to design T-cell epitopes candidate targeting the conserved-KRAS as cancer immunotherapy. KSFEDIHHY is the best epitope candidate from a series of assays conducted. This candidate epitope has a good immunogenicity score, predicted to be able to bind with many HLA supertypes, non-allergenic and non-toxic. KSFEDIHHY can make a complex with HLA B*57:01 with binding affinity -7.8 kcal/mol. Prediction analysis for both sequence-based and structure-based shows that KSFEDIHHY has the potential to be developed as an epitope candidate for cancer vaccines.
Keyword: reverse vaccinology, HLA class I, T-cell epitope