Judul: Effectiveness of Clove Leaves (Syzygium aromaticum) Infusion As Antidiarrheal in Mice (Mus musculus)
Abstrak: Diare adalah penyakit gastrointestinal yang umum terjadi pada berbagai spesies hewan, dengan implikasi yang signifikan terhadap kesehatan dan produktivitas hewan. Penelitian ini menyelidiki khasiat infusa daun cengkeh sebagai agen antidiare pada mencit (Mus musculus). Sebanyak 30 ekor mencit dibagi menjadi lima kelompok, yaitu kontrol negatif, kontrol positif, konsentrasi infusa daun cengkeh 100%, 50%, dan 25%. Tahapan penelitian meliputi skrining fitokimia dan uji antidiare dengan methode proteksi intestinal. Mencit diberikan berbagai perlakuan secara oral berdasarkan pembagian kelompok pada metode proteksi usus dan dipantau selama 9 jam. Parameter yang digunakan dalam metode proteksi intestinal yakni frekuensi defekasi, konsistensi feses, awal mula dan durasi diare. Analisis fitokimia menunjukkan adanya kandungan alkaloid, flavonoid, saponin, dan tanin pada ekstrak daun cengkeh. Uji ANOVA satu arah dan uji Tukey digunakan untuk menganalisis data. Hasil penelitian menunjukkan konsentrasi infusa daun cengkeh 25% dan 50% tidak efektif, sedangkan konsentrasi infusa daun cengkih 100% efektif sebagai antidiare pada mencit. Konsentrasi infusa daun cengkeh 100% terbukti efektif sebagai antidiare., Diarrhea is a prevalent gastrointestinal ailment affecting various animal species, with significant implications for animal health and productivity. This study investigates the efficacy of Clove leaves infusion as an antidiarrheal agent in mice (Mus musculus). A total of 30 mice were divided into five groups: negative control, positive control, 100%, 50%, and 25% concentration of Clove leaves infusion. Intestinal protection methods and phytochemical screening test are used. Mice were orally administered various treatments based on group divisions in the intestinal protection method and monitored for 9 hours. The parameters used in the intestinal protection method are defecation frequency, stool consistency, and the onset and duration of diarrhea. Phytochemical analysis confirmed the presence of alkaloids, flavonoids, saponins, and tannins in the Clove leaves extract. ANOVA one-way test and Tukey tests were used to analyze the data. The result showed that 25% and 50% concentration of Clove leaves infusion are not effective while 100% concentration of Clove leaves infusion is effective as antidiarrheal in the mice. 100% concentration of Clove leaves infusion has show the effectiveness as an antidiarrheal.
Keyword: antidiare, infusa, mencit, antidiarrheal, infusion, mice, daun cengkeh, Clove leaves

Judul: Effectiveness of Tamarind Leaf Infusion (Tamarindus indica L.) as an Antidiarrheal in Mice (Mus musculus)
Abstrak: Asam jawa merupakan tanaman herbal yang memiliki khasiat untuk mengobati berbagai penyakit, namun belum ada penelitian ilmiah mengenai aktivitas infusa daun asam jawa sebagai antidiare. Penelitian ini bertujuan untuk menentukan konsentrasi infusa daun asam jawa yang efektif dalam memberikan efek antidiare pada mencit. Penelitian ini juga bertujuan untuk menganalisis kandungan senyawa metabolit sekunder. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok yang terdiri dari kontrol negatif (Tween 80 [1%]), kontrol positif (Loperamid HCl), dan tiga kelompok yang diberi perlakuan infusa daun asam jawa dengan konsentrasi bertingkat (25%, 50%, dan 100%). Parameter yang digunakan dalam metode proteksi intestinal adalah frekuensi defekasi, konsistensi feses, waktu awal terjadinya diare, durasi, dan waktu penyembuhan diare. Hasil yang diperoleh menunjukkan ekstrak infusa daun asam jawa sebagai antidiare memiliki kemampuan menurunkan frekuensi defekasi, meningkatkan konsistensi feses, menunda terjadinya diare, dan memperlama waktu penyembuhan diare. Hasil uji fitokimia dari infusa daun asam jawa mengandung flavonoid, steroid, dan terpenoid. Semua kelompok ekstrak infusa daun asam jawa memberikan hasil yang efektif sebagai antidiare., Tamarind is an herbal plant that has properties to treat various diseases, but there has been no scientific research on the activity of tamarind leaf infusion as antidiarrheal. This study aims to determine the concentration of tamarind leaf infusion that is effective in providing antidiarrheal effects on mice. This study also aims to analyze the content of secondary metabolite compounds. This study used 30 mice divided into 5 groups consisting of negative control (Tween 80 [1%]), positive control (Loperamide HCl), and three groups treated with tamarind leaf infusion with graded concentrations (25%, 50%, and 100%). The parameters used in the intestinal protection method were frequency of defecation, stool consistency, time of onset of diarrhea, duration, and healing time of diarrhea. The results obtained showed that tamarind leaf infusion extract as an antidiarrheal agent has the ability to reduce the frequency of defecation, increase stool consistency, delay the onset of diarrhea, and prolong the healing time of diarrhea. Phytochemical test results of tamarind leaf infusion contain flavonoids, steroids, and terpenoids. All groups of tamarind leaf infusion extracts provide effective results as antidiarrheal.
Keyword: antidiare, daun asam jawa, infusa

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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