Judul: Peningkatan Kinerja Sistem Spatial Data Warehouse Kebakaran Hutan Menggunakan GeoServer dan GeoMondrian
Abstrak: Forest fire can be periodically detected by satellite as hotspot areas that occur at specified time and location. The frequency of forest fire in Indonesia is high so the data collection of hotspots will be very large. That data collection of hotspots can be stored into specific storage such as data warehouse. A data warehouse system of forest fire was built in the previous research using GeoServer as web map server and GeoMondrian as OLAP Server. However, that system still has some limitations such as the poor system runtime and the low amount of retrieved hotspots. In this research, the system would be reconfigurated in order to fix those limitations so that the system performance would increase. The configuration involves some part of the system including Java Runtime Environment, database source, data cube schema, and error handling in OpenLayers. It has resulted 155 ms higher speed of runtime and 1310 higher number of retrieved hotspots.
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Judul: Forest Fire Spatio-Temporal Data Warehouse using GeoMondrian and GeoServer
Abstrak: Indonesia is a country that has tremendous wealth of forests in the world. But Indonesia's forests decreases each year by deforestation amounted to 1.87 million hectares (FAO 2007). One of the main causes of deforestation in Indonesia is forest fires. Catastrophic forest fires cause major problems and need complex ways to overcome. One form of forest fire prevention is monitoring hotspots using the National Oceanic and Atmospheric Administration (NOAA) satellites. This satellite imagery capturing the form of hotspots, which could indicate the existence of forest fires based on location and time. Data obtained from these satellites have particularly large amount, causing the accumulation of data hotspot. This can be overcome by the presence spatio-temporal data warehouse technology with Spatial Online Analytical Processing (SOLAP) applications. Spatio-temporal data warehouse capabilities in integrating data into a quick and comprehensive information to assist decision-making process in terms of controlling forest fires. This study developed a geographic information system that integrates data warehousing applications spatio-temporaly with Spatial On-Line Analytical Processing (SOLAP) application using the framework Geomondrian and Geoserver as a web map server. Pre-process data such as data extraction, data transformation and loading of data, performed before the data warehouse is built in accordance with the dimensional data model (the concept of design in building a data warehouse) and integrated with Geoserver that handles the presentation of data in map form. The system was developed to visualize data of forest fires in the form of pivot tables, graphs and maps spread of hotspots in a web-based environment, so the system can support decision-making in an effort to control forest fire in Indonesia.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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