Judul: Analisis Hematologi dan Kimia Darah Macaca Fascicularis dengan Infeksi Positif terhadap Klebsiella Pneumoniae
Abstrak: Klebsiella pneumoniae belongs to the family Enterobacteriaceae and is found in mouth and intestine. Klebsiella pneumoniae has been reported in various nonhuman primate species with the cases of pneumonia, septicemia, and enteritis. This secondary study purposed to obtain information of clinical pathology profile related to Klebsiella infection in cynomolgus monkeys (Macaca fascicularis). This secondary study was conducted on three long-tailed monkeys which showed positive results in the bacterial culture test. The secondary study was based on blood analysis to evaluate hematology and blood chemistry. The results demonstrate that monkeys with Klebsiella pneumoniae exhibited marked changes in erythrocytes, hemoglobin, hematocrit and mean corpuscular hemoglobin concentration values in hematology as well as creatinine, total protein, and albumin levels and albumin/globulin ratio in blood chemistry profile. The changes may indicate the incidence of anemia, liver disease, thrombocytopenia, dehydration, inflammatory response and kidney disease, which may be associated with Klebsiella pneumoniae infection.
Keyword: Blood chemistry analysis, Hematological analysis, Klebsiella pneumoniae, Macaca Fascicularis

Judul: Case Study of the Hematological Profile  of A Colony Macaca fascicularis in PSSP with Klebsiella pneumoniae Infection
Abstrak: Monyet ekor panjang (Macaca fascicularis) adalah hewan model karena memiliki kemiripan dengan manusia secara morfologis. Informasi mengenai profil hematologi monyet ekor panjang dengan kasus Klebsiella pneumoniae masih sangat terbatas. Hasil penelitian ini diharapkan dapat menjadi salah satu rujukan pada kasus Klebsiella pneumoniae pada monyet ekor panjang. Data sampel didapatkan dari lab PSSP sejumlah 27 sampel darah yang sudah dianalisis dengan alat hematology analyzer dan PCR. Data kemudian dianalisis secara deskriptif dan ditampilkan dalam bentuk rata-rata ± standar deviasi. Data tersebut dibandingkan dengan profil hematologi Macaca fascicularis normal. Nilai profil hematologi rata- rata pada Macaca fascicularis di penangkaran PSSP baik dari yang positif dan negatif Klebsiella pneumoniae mengalami penurunan adalah leukosit, eritrosit, hemoglobin hematokrit, MCV, trombosit dan PDW, sedangkan yang mengalami kenaikan adalah MCH, MCHC dan RDW. Hal ini menunjukkan terjadinya leukopenia, anemia mikrositik hiperkromik, dan trombositopenia yang dapat terjadi akibat infeksi Klebsiella pneumoniae., The long-tailed monkey (Macaca fascicularis) is a model animal because it is morphologically similar to humans. Information on the hematological profile of long-tailed monkeys with Klebsiella pneumoniae cases is still very limited. The results of this study are intended to serve as a reference in the case of Klebsiella pneumoniae in long-tailed monkeys. The sample data was obtained from the PSSP laboratory. A total of 27 blood samples were analyzed using a hematology analyzer and PCR. The data were then analyzed descriptively and presented in terms of mean and standard deviation. These data were compared with the normal Macaca fascicularis hematological profile. The mean values of the hematological profile in captive Macaca fascicularis of PSSP, both positive and negative Klebsiella pneumoniae, were decreased in leukocytes, erythrocytes, hemoglobin, hematocrit, MCV, platelets, and PDW, while those showing an increase in MCH, MCHC, and RDW. This indicates the occurrence of leukopenia, hyperchromic microcytic anemia, and thrombocytopenia, which can occur due to infection with Klebsiella pneumoniae.
Keyword: Klebsiella pneumoniae, Macaca fascicularis, profil hematologi, Hematology profile

Judul: Formulasi TSP (Traveling Salesman Problem) menggunakan ILP (Integer Linear Programming)
Abstrak: TSP is a journey of salesman f?om his origin town (place) to visit n-cities (places) only at once, then return to his origin town (place) with a minimum total distance. Its purpose is to minimize the operating expense that is released by the company. Vehicle route at TSP in the form of a Hamiltonian cycle, that is closed path containing all nodes at the graph which representing a network walk. Its problem is to determine a journey route which is feasible (possibly can be passed by) in such a way the vehicle travelled distance passed the route is minimum.
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