Judul: Pola Pertumbuhan Remaja Usia 15 Sampai 20 Tahun  Di Wilayah Bogor
Abstrak: Growth continues from conception, pregnancy, baby, children, adolescence until adulthood. Adolescence growth pattern description can be used as a reference. This research aims to determine normal growth pattern of height, weight, and body mass index of Bogor adolescence aged 15 to 20. Cross-sectional sampling were conducted to get probands from SMPN 2, SMUN 3, SMUN 4, SMUN 8 Bogor City, and IPB in order to obtain probands with socioeconomic background above average. Growth pattern derives from 50th percentile. Male adolescence height grows until the age of 18 and ceases to grow afterwards. Female adolescence height ceases to grow at the age of 18 years old. Maximum male adolescence height is 169.27 cm while maximum female height is 156.74 cm. Male adolescence weight increases until the age of 20 while female adolescence ceases to grow at the age of 19. Maximum male adolescence weight is 57.08 kg while maximum female weight is 50.96 kg. Body mass index of male and female adolescence increases slightly in rate. Body mass index in male and female reaches maximum in the age of 20. That is equal to 20.25 kg/m2 for male adolescence and 20.47 kg/m2 for female adolescence.
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Judul: Pola pertumbuhan anak usia 1-5 tahun di wilayah Bogor
Abstrak: Setiap anak mempunyai pola pertumbuhan badan dengan besar dan lajunya sendiri. Pengukuran secara antropometri dapat menilai status kesehatan dengan membandingkan terhadap pola pertumbuhan yang umum. Oleh karena itu sangat penting bagi Indonesia memiliki acuan pertumbuhan sendiri sebagai referensi. Tujuan penelitian ini adalah untuk mengetahui pola pertumbuhan anak usia 1-5 tahun di wilayah Bogor. Probandus adalah anak berusia 1-5 tahun yang berasal dari wilayah Bogor. Data yang diambil adalah data antropometri yang meliputi berat badan dan tinggi badan. Pengambilan data dilakukan secara horisontal, artinya pengukuran dilakukan pada probandus yang didapatkan pada satu kali kesempatan di posyandu-posyandu, Rumah Sakit, Play group dan TK. Pola pertumbuhan anak laki-laki dan perempuan dilihat pada persentil 50. Pertumbuhan anak laki-laki dan anak perempuan usia 1-5 tahun terus mangalami peningkatan. Rata-rata kenaikan tinggi badan anak laki-laki lebih besar daripada anak perempuan. Demikian pula rata-rata kenaikan berat badan anak laki-laki lebih besar dari anak perempuan
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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