Judul: Studi Histopatologi Organ Otak dan Paru-Paru Hamster dan Mencit yang Diinfeksi Coxiella burnetii
Abstrak: This study aims were to describe histopathological lesions of the brain and lungs of hamster and mice were infected with bacterium Coxiella burnetii using Hematoxylin Eosin (HE) staining and immunohistochemistry (IHC) technique. A total of 3 groups of experimental animals, consists of group I (hamster A), group II (hamster B), and group III (mice). Group I infected with bacterium Coxiella burnetii, maintained for 5 days then were euthanazied by 0.25 ml diazepam and colected brain and lungs to be the first sample. Spleen of this group was extracted and infected to group II. This procedure was repeated from group II to group III. The results showed lesions in the form of infiltration of inflammatory cells, congestion, hemorrhage, edema, and necrosis of the brain in all three groups of animals with different levels of severity. Lesions in the lung organ showed infiltration of inflammatory cells, congestion, hemorrhage, emphysema, and edema. IHK staining showed positive results in both brain and lungs whether hamsters or mice.
Keyword: lung, Coxiella burnetii, brain

Judul: Studi Histopatologi Organ Hati Hamster (Mesocricetus auratus) yang Diinfeksi Coxiella burnetii
Abstrak: Coxiella burnetii (C. burnetii) is a bacterial like organism that causes Query fever. The aim of this study was to describe the liver histopathology of hamsters after infected by C. burnetii intraperitoneally. Hamster were divided into two groups. All hamster liver were collected for histopathological examination using hematoxylin-eosin staining (HE) and immunohistochemical staining (IHC). HE staining results in hamsters group I which were injected with C. burnetii’s antigen showed 3 out of 4 has granuloma which are typical of C. burnetii infection. All hamsters group II which were injected with hamsters group I’s spleen extracts showed granuloma in microscopic observation. IHC staining revealed all hamsters liver has positive result. Beside granuloma lesion, all hamster’s liver show acute hepatitis symptoms. The microscopic lesion of acute hepatitis showed the inflammatory cell accumulated in liver perifer, degeneration of hepatocytes cells, activation of lymphoid follicles, as well as congestion in small and large blood vessels.
Keyword: C. burnetii, granuloma, hamster, HE, histopathology, IHC

Judul: Perubahan Garis Pantai di Pesisir Utara Babo, Teluk Bintuni, Provinsi Papua Barat.
Abstrak: Garis pantai dapat berubah secara terus menerus dan pemantauan perubahannya dapat dilakukan menggunakan teknologi pengindraan jauh. Penelitian ini bertujuan mengidentifikasi perubahan garis pantai dan faktor penyebabnya di Pesisir Utara Babo, Teluk Bintuni, Provinsi Papua Barat tahun 1990 – 2019 menggunakan data satelit Landsat. Ekstraksi garis pantai dilakukan menggunakan metode Normalize Difference Vegetation Index (NDVI) dan Tasseled Cap untuk menghasilkan fitur garis pantai. Sedangkan perubahan garis pantai dihitung menggunakan Digital Shoreline Analysis System (DSAS) dengan metode Net Shoreline Movement (NSM) dan End Point Rate (EPR). Tinggi gelombang dan kecepatan arus di bagian dalam Teluk Bintuni cenderung lebih kecil dibandingkan di bagian mulut teluk. Hasil analisis DSAS menunjukkan bahwa di wilayah Pesisir Utara Babo tahun 1990-2019 sebagian besar mengalami abrasi, sedangkan akresi hanya terjadi di beberapa lokasi. Abrasi terbesar terjadi pada subzona D1 (Desa Tanah Merah) yaitu sebesar 56.91 m pada tahun 1990-2000 dengan laju perubahan 5.26 m/tahun dan akresi terbesar terjadi pada subzona D3 (Desa Tofoi) sebesar 97.16 m pada tahun 2000-2010 dengan laju perubahan 8.90 m/tahun. Perubahan garis pantai terbesar selama rentang tahun 1990-2019 terjadi pada subzone D3 dengan nilai sebesar 226.2 dan laju perubahan 7.91. Perubahan garis pantai di wilayah ini dominan dipengaruhi oleh fenomena pasang surut, selain itu hantaman gelombang, arus susur pantai (longshore current), masukkan sedimen dari sungai dan adanya alih fungsi lahan juga mempengaruhi terjadinya abrasi dan akresi.
Keyword: abrasi, akresi