Judul: Strategi Adaptasi terhadap Perubahan Iklim pada Ekowisata di Taman Wisata Alam Telogo Warno Telogo Pengilon dan Nama NIM Sekitarnya
Abstrak: The issue of climate change has occurred in Indonesian over the last few years is expected to potentially affect ecotourism activities at Nature in Tourism Telogo Warno Telogo Pengilon Park (TWATWTP). These adaptation startegies against climate change are needed by managers and the community, so that tourism remains in this area. The aim of this research was to prepare the adaptation strategy to climate change on ecotourism at TWATWTP and surroundings areas. Data collection in this research used literature study, observations and interview method. Data was analyzed by analysis descriptive. The changing climate on TWATWTP increasing temperature, humidity and rainfall. Strategy for adaptation to climate change can be done by implementing ecotourism cooperation between BMKG and tourism management. The climate change impact on peoples and tourists so that can be used as new tourist attraction which is frost.
Keyword: Bogor Agricultural University (IPB), ecotourism, climate change, adaptation

Judul: Dampak Pengembangan Ekowisata: Struktur Nafkah serta Adaptasi dan Mitigasi Perubahan Iklim Rumah Tangga.
Abstrak: Ekowisata merupakan kegiatan pariwisata yang mengandalkan kondisi alam dan lingkungan sebagai destinasi wisata. Kehadiran wisata dapat berpengaruh terhadap kondisi nafkah rumah tangga pedesaan di sekitar wilayah wisata. Selain itu, ekowisata juga dapat menjadi kegiatan untuk adaptasi dan mitigasi perubahan iklim. Tujuan dari penelitian ini adalah untuk menganalisis struktur nafkah rumah tangga pedesaan yang diakibatkan karena kehadiran ekowisata dan bagaimana kegiatan adaptasi dan mitigasi perubahan iklim yang dilakukan rumah tangga di wilayah ekowisata. Penelitian ini menggunakan metode penelitian campuran. Jumlah responden dalam penelitian ini sebanyak 60 rumah tangga dengan komposisi 30 rumah tangga pekerja wisata dan 30 rumah tangga bukan pekerja wisata. Penelitian ini menggunakan uji hubungan Rank spearman dan uji Wilcoxon signed rank test. Hasil penelitian menunjukan bahwa pengembangan ekowisata menyebabkan perubahan modal nafkah sosial, manusia, fisik, dan finansial. Penelitian ini juga menemukan sumber nafkah baru yaitu pariwisata. Kegiatan ekowisata juga dapat menjadi adaptasi dan mitigasi perubahan iklim yang sekaligus dapat menjadi kegiatan untuk melestarikan wilayah ekowisata agar lebih berkelanjutan., Ecotourism is a tourism activity that relies on natural and environmental conditions as a tourist destination. The presence of tourists can affect the livelihood conditions of rural households around tourist areas. In addition, ecotourism can also be an activity for climate change adaptation and mitigation. The purpose of this research is to analyze the livelihood structure of rural households caused by ecotourism and how climate change adaptation and mitigation activities are carried out by households in ecotourism areas. This study uses mixed research methods. The number of respondents in this study were 60 households with a composition of 30 tourist worker households and 30 non-tourist worker households. This study used the Spearman rank relationship test and the Wilcoxon signed rank test. The results of the study show that the development of ecotourism causes changes in social, human, physical and financial livelihood capital. This research also found a new source of income, namely tourism. Ecotourism activities can also be climate change adaptation and mitigation which can also be activities to preserve ecotourism areas to make them more sustainable.
Keyword: adaptation, climate change, ecotourism, livelihood structure, mitigation

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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