Judul: Basis data spasial agroklimatologi studi kasus Kabupaten Bogor
Abstrak: Iklim merupakan salah satu sumber daya alarn yang perlu diperhitungkan dalam pengembangan daerah, sehingga keterkaitan iklim dalarn pembangunan dan pengembangan daerah tertentu tidak dapat dipisahkan. Berdasarkan pengetahuan tentang keadaan iklim suatu daerah, maka dapat disusun perencanaan pembangunan yang tepat, terutama pembangunan bidang pertanian. Semenjak diperkenalkannya revolusi hijau, konsep tradisionaJ dalam pendugaan iklim perlahan mulai ditinggalkan, sumber daya alam seperti infonnasi tentang iklim sulit untuk diperoleh oleh pengguna dan pengambil keputusan (petani dan pemerintah). Oleh sebab itu digunakan suatu teknologi pengumpulan, pendugaan dan pengklasifikasian iklim dengan menggunakan Sistem Informasi Geografi (SIG) dan pemodelan komputer. Tersedianya samoa ini diharapkan pendugaan iklim dan pengklasiflkasiannya lebih mudah dianalisa, sehingga memudahkan penyusunan pewilayahan tanaman di suatu daerah dan penyusunan basisdata spasial agroklimatologi. Atas dasar ide tersebut disusun sebuah model klasifikasi ildim yang
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Judul: Iklim di Wilayah Bogor
Abstrak: Iklim berpengaruh besar terhadap aktivitas manusia. Oleh karena itu, informasi tentang faktor dan variasi iklim sangat diperlukan untuk berbagai kegiatan dan perencanaan. Penelitian ini bertujuan untuk mengetahui pola beberapa unsur dan klasifikasi iklim di Wilayah Bogor. Data yang digunakan dalam penelitian ini adalah data iklim observasi, data luaran model (Terra Climate), data Landsat, dan data elevasi wilayah dari SRTM. Data model dikoreksi menggunakan Koreksi Bias Piani. Hasil penelitian menunjukan bahwa suhu udara rata-rata di Wilayah Bogor berkisar antara 14 - 27ᵒC. Diurnal Temperatur Range (DTR) merupakan selisih nilai rata-rata bulanan antara suhu udara maksimum dan minimum. DTR di Citeko menunjukan tren menurun, sedangkan di Dramaga tren DTR meningkat. Tren DTR menurun di Citeko disebabkan adanya peningkatan suhu minimum yang lebih besar dibanding suhu maksimum. Tren DTR meningkat di Dramaga juga menunjukan perubahan tetapi dengan sifat berbeda, disebabkan suhu maksimum meningkat tetapi suhu minimum tetap. Curah hujan di Wilayah Bogor berkisar antara 25 - 500 mm. Kelembaban relatif bulanan di Wilayah Bogor berkisar antara 65 - 96%. Radiasi netto di Wilayah Bogor berkisar antara 6 -13 MJ/m2 /hari. Evapotranspirasi di Wilayah Bogor berkisar antara 65 - 130 mm/bulan. Klasifikasi iklim di Wilayah Bogor adalah Af, Am, dan mirip dengan C (iklim dataran tinggi) untuk klasifikasi Koppen, A1, B1, B2, C1, dan C2 untuk Oldeman, A dan B untuk klasifikasi Schmidt-Ferguson. Kombinasi ketiga klasifikasi iklim di Wilayah Bogor meliputi 10 kelas yang menunjukan bahwa Wilayah Bogor merupakan wilayah yang basah., Climate has a big influence on human activities. Therefore, the information about factor and variation of climate are needed for various planning and activities. This study aims are to determine the pattern of several elements and climate classifications in the Bogor Region. The data used in this study are climate observation data, model output data (Terra Climate), Landsat Data, and regional elevation data from SRTM. The data model was corrected by Piani’s Bias correction. The result is showing the average air temperature in the Bogor Region ranges from 14 – 27 oC. Diurnal Temperature Range (DTR) is the difference in the monthly average value between the maximum and minimum air temperatures. The DTR in Citeko shows a downward trend, while in Dramaga the DTR shows a increase trend. The downward trend on DTR in Citeko indicate a change in air temperature. The minimum temperature increase greater than the maximum temperature. The increasing trend on DTR in Dramaga also indicates a change in temperature, but with a difference nature due to the increase in maximum temperature while the minimum temperature remain constant. The rainfall in the Bogor Region ranges from 25 - 500 mm. The monthly relative humidity in the Bogor Region ranges from 65 - 96%. The net radiation in the Bogor Region ranges from 6 -13 MJ/m2 /day. Evapotranspiration in the Bogor Region ranges from 65 - 130 mm/month. The climate classifications Bogor Region are Af, Am, and similar to C (upland climate) for the Koppen classification, A1, B1, B2, C1, and C2 for Oldeman, A and B for the Schmidt-Ferguson classification. The combination of climate classifications in the Bogor Region include 10
Keyword: altitude, climate classification, climate factor, climate variation

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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