Judul: Hubungan Pelapisan Sosial Peternak Domba Dengan Keterlibatannya Dalam Jaringan Komunikasi Di Desa Gunung Seureuh Kecamatan Leuwiliang Kabupaten Bogor
Abstrak: Studi ilmu komunikasi sudah sangat mendesak untuk segera dilakukan dalam rangka pengembangan dan pemberdayaan peternak sebagai pelaku utama pembangunan sub sektor peternakan. Salah satu upaya yang dapat ditempuh adalah melalui kajian yang mendalam tentang jaringan komunikasi untuk memperlihatkan arus informasi yang tejadi, "kepada siapa" peternak mendapatkan informasi dan "kepada siapa" peternak menyebarkan informasi tentang usaha ternak domba. Tujuan penelitian ini adalah untuk mengetahui: (1) pelapisan sosial peternak domba, (2) gambaran jaringan komunikasi peternak domba dan (3) hubungan antara pelapisan sosial peternak domba dengan keterlibatannya dalam jaringan komunikasi di Desa Gunung Seureuh, Kecamatan Leuwiliang, Kabupaten Bogor
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Judul: Perilaku komunikasi dan jaringan komunikasi peternak domba tentang sapta usaha peternakan (kasus pada peternak domba di desa Cigudeg, kecamatan Cigudeg, kabupaten Bogor)
Abstrak: The aim of research were to : (1) describe individual characteristic of sheep farmers in Cigudeg Village, (2) describe sheep farmers communication behaviour regard to seven efforts of animal husbandry (SUP) in Cigudeg Village, (3) describe communication roles regard to SUP which occured in their communication network, and (4)analyze correlation between their individual characteristics and communication role, their communication behaviour and communication role regard to SUP which occured in their communication network.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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