Judul: Strategi BKP5K dalam Menunjang Penganekaragaman Pangan di Kabupaten Bogor
Abstrak: The purposes of this research are (1) to identify internal and external factors of BKP5K in order to support food-diversification in Bogor (2) to formulate alternative strategies (3) to formulate the priority of strategies by architercture strategy approach. Analytical instruments used are internal and external analysis, SWOT matrix, and architecture strategy. The obtained strategies are optimalization of food security development council in subdistrict level; BKP5K’s budget is focused in food security establishment; initiation of food production area based on the subdistrict’s potential; formulating the policy of area management by the manager; formulating the policy of trading agreement between food production area; guiding and training all staffs; formulating the policy food production area institution is cooperative; formulating the policy of transferring the development of one commodity to another one; formulating the policy to infiltrate local food knowledge in elementary up to high school curriculum; formulating the policy of development food storage; and formulating the policy of development food information system. Architecture strategy arranges the priority strategy implementation, main stakeholders, up to program which is supporting strategy.
Keyword: SWOT analysis., Kabupaten Bogor, food consumption diversification, BKP5K, architecture strategy

Judul: Strategi Peningkatan Konsumsi Pangan di Kota Bogor
Abstrak: Tujuan dari penelitian ini adalah (1) menganalisis situasi konsumsi pangan di Kota Bogor, (2) Merumuskan alternatif strategi berdasarkan analisis SWOT sesuai dengan faktor internal dan eksternal yang berpengaruh terhadap peningkatan konsumsi pangan di Kota Bogor, dan (3) Merumuskan prioritas strategi peningkatan konsumsi pangan di Kota Bogor berdasarkan metode AHP (Analitical Hierarchy Process). Data yang dikumpulkan adalah data skunder dan data primer. Data sekunder dianalisis secara deskriptif untuk mengetahuai kondisi aktual konsumsi pangan di Kota Bogor dan merumuskan faktor internal dan faktor eksternal lingkungan strategi konsumsi pangan. Data primer dikumpulkan melalui wawancara dan kuisioner. Hasil dari penelitian ini menunjukan konsumsi pangan di Kota Bogor secara kuantitas mencapai 88.8% dari AKE, secara kualitas mencapai 81.8 dari skor PPH. Strategi peningkatan konsumsi pangan di Kota Bogor berada pada kuadran I (mendukung strategi agresif). Prioritas strategi pertama dalam peningkatan konsumsi pangan adalah meningkatkan akses dan ketersediaan pangan.
Keyword: AHP, konsumsi pangan, strategi kebijakan, SWOT

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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