Judul: Potensi Ekstrak Buah Makasar (Brucea javanica (L.) Merr) sebagai Antihipertensi
Abstrak: It is believed that people like to consume fatty and salty food which lead to hypertension. They used antihypertensive drug to control hypertension, however, intolerant side effects could appear. It brings them to find another healing like Indonesian herbs. The aim of this research was examine the antihypertensive potency of aqueous and hexane fraction of brucea fruit. This research used 2 months old Sprague Dawley male rats which hypertensived by adrenaline injection. The ripe brucea fruit was used in this research. At the beginning, researcher oriented the respon time of samples. Systolic blood pressure was measured by indirect method. It used bisoprolol’s dose which is 0.0714 mg/kg body’s weight as antihypertensive agent standart to samples as well. Hexane and aqueous fraction then bisoprolol achieved hypotension at minute 20th, 60th, and 80th via oral. Hypertensive effect of adrenaline was achieved at minute 20th via intraperitoneal. Both hexane and aquoeus fractions had antihypertensive potency because of its ability to decrease the raising of systolic blood pressure due to adrenaline about 27.66% and 34.40% higher than standart about 11.65%.
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Judul: Potensi Buah Makasar (Brucea javanica (L.) Merr) sebagai Inhibitor Enzim α-Glukosidae
Abstrak: Brucea fruit is one Indonesian medicine plants which rich in advantages. Empirically, brucea fruit can decrease blood glucose concentration for patient of diabetes mellitus. Water fraction of brucea fruit extract have been observed to determine its ability as antidiabetic would be compared with acarbose as positive control in same concentration (1%). Antidiabetic test in water and hexane fraction of brucea fruit extract use α-glucosidase inhibition method. Antidiabetic activity has been measured by formation of p-nitrophenol from enzymatic reaction of nitrophenil--D-glucopyranose (p-NPG) which is catalyze by α-glucosidase enzyme. The formation of p-nitrophenol was measured by spectrophotometer at λ=400 nm. Phytochemistry test showed that water fraction contains alkaloid and flavonoid, whereas hexane fraction only contain alkaloid. The result of this research is water fraction and hexane of brucea fruit (Brucea javanica (L.) Merr) at concentration 1% (b/v) can inhibit α-glucosidase enzyme activity 14.32% and 12.76%, whereas Acarbose as positive control can inhibit α-glucosidase enzyme activity 81.15%.
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Judul: igenvalues and Eigenvectors of Tridiagonal Matrix with Non Constant and Recurrent Diagonal Entries.
Abstrak: Matriks tridiagonal adalah suatu matriks yang mempunyai entri-entri bernilai nol kecuali pada diagonal utama, di bawah diagonal utama (subdiagonal) dan di atas diagonal utama (superdiagonal). Entri pada diagonal utama tidak konstan dan berulang. Setiap entri pada matriks tridiagonal ini adalah bilangan kompleks. Dalam karya ilmiah ini, akan dibuktikan 3 teorema untuk menentukan nilai eigen dengan 2 kasus dan 1 teorema untuk menentukan vektor eigen. Teorema pertama menentukan polinomial karakteristik dari matriks tridiagonal. Polinomial karakteristik dari matriks tridiagonal tersebut digunakan untuk menentukan nilai eigen pada teorema kedua dan ketiga serta menentukan vektor eigen pada teorema keempat
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