Judul: Effectiveness of jintan putih (Cuminum  cyminum) infusion as antidiarrheal in mice (Mus musculus)
Abstrak: Jintan putih merupakan tanaman yang sudah sejak lama dikonsumsi sebagai bahan masakan dan obat, namun belum terdapat penelitian terkait manfaat jintan putih sebagai antidiare. Penelitian ini bertujuan mengetahui efektivitas infusa jintan putih sebagai antidiare dan menentukan konsentrasi yang memiliki efek antidiare paling efektif. Penelitian ini juga bertujuan mengetahui kandungan metabolit sekunder pada jintan putih melalui penapisan fitokimia. Pengujian antidiare dilakukan dengan menggunakan metode proteksi intestinal dengan pemberian sediaan secara peroral. Parameter yang diamati pada metode proteksi intestinal yaitu frekuensi defekasi, konsistensi feses, dan durasi diare. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok terdiri dari kontrol negatif (Tween-80 [1%]), kontrol positif (Loperamide HCl), dan kelompok perlakuan infusa jintan putih konsentrasi 25, 50, dan 100%. Konsentrasi 25% merupakan konsentrasi yang paling efektif, karena menghasilkan durasi diare paling pendek. Penapisan fitokimia infusa jintan putih menunjukkan terdapat senyawa metabolit sekunder meliputi alkaloid, saponin, flavonoid, tanin, dengan tanin sebagai senyawa yang paling berpotensi sebagai antidiare., White cumin is a plant that has long been consumed as a food and medicine ingredient however, there has been no research related to the benefits of white cumin as antidiarrheal. This study aims to determine the effectiveness of white cumin extract as antidiarrheal and determine the concentration that has the most effective antidiarrheal effect. This study also aims to determine the content of secondary metabolites in white cumin through phytochemical screening. Antidiarrheal testing was carried out using the intestinal protection method by administering the preparation orally. Parameters observed in the intestinal protection method are frequency of defecation, consistency of feces, and duration of diarrhea. This study used 30 mice divided into 5 groups consisting of a negative control (Tween-80 [1%]), positive control (Loperamide HCl), and treatment groups of white cumin infusion with concentrations of 25, 50, and 100%. The 25% concentration is the most effective concentration, because it produces the shortest duration of diarrhea. Phytochemical screening of white cumin infusion showed that there were secondary metabolite compounds including alkaloid, saponin, flavonoid, tannin, with tannin as the most potential antidiarrheal compound.
Keyword: antidiare, infusa, proteksi intestinal, infusion, intestinal protection, jintan putih, penapisan fitokimia, antidiarrhea, phytochemical test

Judul: Effectiveness of Tamarind Leaf Infusion (Tamarindus indica L.) as an Antidiarrheal in Mice (Mus musculus)
Abstrak: Asam jawa merupakan tanaman herbal yang memiliki khasiat untuk mengobati berbagai penyakit, namun belum ada penelitian ilmiah mengenai aktivitas infusa daun asam jawa sebagai antidiare. Penelitian ini bertujuan untuk menentukan konsentrasi infusa daun asam jawa yang efektif dalam memberikan efek antidiare pada mencit. Penelitian ini juga bertujuan untuk menganalisis kandungan senyawa metabolit sekunder. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok yang terdiri dari kontrol negatif (Tween 80 [1%]), kontrol positif (Loperamid HCl), dan tiga kelompok yang diberi perlakuan infusa daun asam jawa dengan konsentrasi bertingkat (25%, 50%, dan 100%). Parameter yang digunakan dalam metode proteksi intestinal adalah frekuensi defekasi, konsistensi feses, waktu awal terjadinya diare, durasi, dan waktu penyembuhan diare. Hasil yang diperoleh menunjukkan ekstrak infusa daun asam jawa sebagai antidiare memiliki kemampuan menurunkan frekuensi defekasi, meningkatkan konsistensi feses, menunda terjadinya diare, dan memperlama waktu penyembuhan diare. Hasil uji fitokimia dari infusa daun asam jawa mengandung flavonoid, steroid, dan terpenoid. Semua kelompok ekstrak infusa daun asam jawa memberikan hasil yang efektif sebagai antidiare., Tamarind is an herbal plant that has properties to treat various diseases, but there has been no scientific research on the activity of tamarind leaf infusion as antidiarrheal. This study aims to determine the concentration of tamarind leaf infusion that is effective in providing antidiarrheal effects on mice. This study also aims to analyze the content of secondary metabolite compounds. This study used 30 mice divided into 5 groups consisting of negative control (Tween 80 [1%]), positive control (Loperamide HCl), and three groups treated with tamarind leaf infusion with graded concentrations (25%, 50%, and 100%). The parameters used in the intestinal protection method were frequency of defecation, stool consistency, time of onset of diarrhea, duration, and healing time of diarrhea. The results obtained showed that tamarind leaf infusion extract as an antidiarrheal agent has the ability to reduce the frequency of defecation, increase stool consistency, delay the onset of diarrhea, and prolong the healing time of diarrhea. Phytochemical test results of tamarind leaf infusion contain flavonoids, steroids, and terpenoids. All groups of tamarind leaf infusion extracts provide effective results as antidiarrheal.
Keyword: antidiare, daun asam jawa, infusa

Judul: Bifurkasi Hopf pada Model Siklus Bisnis Kaldor Kalecki tanpa dan dengan Waktu Tunda
Abstrak: Business cycle model is one of dynamical system models in economic. One of the business cycles model is Kaldor-Kalecki model. Kaldor-Kalecki business cycle model that is written in delayed defferential equations, is a business cycle model that involves gross product and capital stock of a company. In this paper Kaldor-Kalecki business cycle model is analyzed using both nondelay and delay in time of capital stock. By Taylor expansion for the time delayed model, an analysis of stability around the fixed points has been done. Furthermore, by using Hopf bifurcation theorem, it can be shown that there exists periodic orbits and limit cycle. In the nondelayed model, changing the parameter of goods market could lead to the occurrence of Hopf bifurcation and the existence of limit cycle. Similarly, for the delayed model, it has been shown that changing the time delay parameter may result in the occurrence of Hopf bifurcation and limit cycle.
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