Judul: Aktivitas antihiperglikemia fraksi air buah makasar (Brucea javanica (L.) Merr) pada tikus yang diinduksi aloksan
Abstrak: Brucea fruit (Brucea javanica (L.) Merr) was known to have a potential antidiabetic activity. This research was aimed to determine antihyperglycemic activity of aqueous fraction from ethanolic extract of brucea fruit in alloxan induced rats. Aqueous fraction of ethanolic extract brucea fruit obtained by maseration using ethanol 95%, which then separated using funnel separator with mixed solution of hexane, methanol, and water (5:9:1) and chloroform:water (1:1). Twenty four rats divided into 6 groups. In the process of raising the blood glucose concentration, one of normal group induced by NaCl 0.9% and the other five treatment groups induced by alloxan (150 mg/kg BW). Afterwards, in the treatment process, normal group and negative control administered by aquadest, positive control administered by glibenclamid (0.25 mg/kg BW), and three other groups administered by aqueous fraction of ethanolic extract brucea fruit in dosage 0.25, 25, and 50 mg/kg BW. Blood glucose concentration of the fasting rats measured at day 0, 3,7,11, and 15. Aqueous fraction from ethanolic extract of brucea fruit contained 3.71% in yield. The result showed that aqueous fraction from ethanolic extract of brucea fruit in dosage 0.25, 25, dan 50 mg/kg BW decreased the blood glucose concentration as many 37.64%, 37.43%, and 60.82% respectively. Aqueous fraction of brucea fruit wich is extracted by ethanol in dosage 50 mg/kg BW has higher activity than glibenclamid in dosage 0.25 mg/kg BW (45.53%).
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Judul: Potensi fraksi air buah makasar (Brucea javanica (L.) Merr) terhadap gambaran histopatologi pankreas tikus yang diinduksi aloksan
Abstrak: Brucea fruit (Brucea javanica (L.) Merr) is one of Indonesian medicine plants which rich in advantages. Empirically, brucea fruit can decrease blood glucose concentration for patient of diabetes mellitus. This research was aimed to determine the effect of aqueous fraction from ethanolic extract of brucea fruit on histopathological in rat pancreas which induced alloxsan. On this research Sprague Dawley rats were divided into 6 groups, each group were 4 rats, group A (Normal), B (alloxan + Glibenclamide 0.25 mg/kg BB), C (alloxan + aquades), D (alloxan + Brucea fruit water fraction 0.25 mg/kg BB), E (alloxan + Brucea fruit water fraction 25 mg/kg BB), dan F (alloxan + Brucea fruit water fraction 50 mg/kg BB). Pancreas histopathological analysis was carried out with Haematoxylin-eosin (HE) staining and observed under light microscope. Reserch showed that aqueous fraction from ethanolic extract of brucea fruit dosage 0.25 mg/kg BB, 25 mg/kg BB, and 50 mg/kg BB can repair the damage of rat pancreas which induced alloxan 150 mg/kg BB. Aqueous fraction from ethanolic extract of brucea fruit dosage 50 mg/kg BB given better restoration effect on the islets of Langerhans than Glibenclamide.
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Judul: Dinamika dan Faktor yang Memengaruhi Permintaan Tenaga Kerja Sektor Konstruksi di Indonesia
Abstrak: Ketersediaan infrastruktur merupakan landasan bagi pembangunan suatu negara. Salah satu sektor yang sangat berperan bagi pembangunan infrastruktur adalah sektor konstruksi. Namun walaupun sektor tersebut cukup memberikan andil yang besar terhadap pembangunan infrastruktur, kondisi ketenagakerjaan pada sektor konstruksi memperlihatkan penurunan jumlah pada tahun 2016-2017. Sehingga tujuan dari penelitian ini yaitu untuk menganalisis dinamika tenaga kerja sektor konstruksi serta faktor-faktor yang memengaruhi permintaan tenaga kerja sektor konstruksi di Indonesia. Metode yang digunakan dalam penelitian ini adalah model panel data. Analisa deskriptif dan kuantitatif digunakan untuk menganalisis dinamika tenaga kerja dan faktor-faktor yang memengaruhi permintaan tenaga kerja sektor konstruksi di Indonesia. Hasil penelitian ini menunjukkan bahwa seluruh variabel independen berpengaruh signifikan terhadap variabel dependen. Variabel PDRB sektor konstruksi berpengaruh positif terhadap permintaan tenaga kerja sektor konstruksi. Sedangkan variabel pengeluaran infrastruktur, pertumbuhan PDRB, dan upah sektoral riil berpengaruh negatif terhadap permintaan tenaga kerja sektor konstruksi di Indonesia.
Keyword: construction, infrastructure, labor dynamics