Judul: Literatur Review: Overview in the Pathology of Infectious Canine Hepatitis in Various Animals
Abstrak: Studi mengenai penyakit menular pada hewan yang disebabkan oleh virus telah banyak dilakukan di berbagai tempat di dunia, salah satu penyakitnya adalah Infectious Canine Hepatitis (ICH). ICH adalah penyakit menular pada anjing dan dapat menular ke hewan lain disebabkan oleh canine adenovirus tipe 1 (CAV-1). Studi literatur ini bertujuan mengkaji gambaran patologi hewan yang terinfeksi ICH dan mengetahui hewan apa saja yang peka terhadap ICH. Hewan yang peka terhadap ICH adalah coyote, rubah, serigala, beruang coklat (Ursos arctos), sigung belang (Mephitis mephitis), dan berang-berang (Lutra lutra). Target utama dari virus CAV-1 adalah sel endotel dan hepatosit. Pemeriksaan patologi-anatomi organ hewan yang terinfeksi ICH menunjukkan hati mudah rapuh, edema dan sedikit membesar. Infark hemoragik pada korteks ginjal. Paru-paru dan dinding kantung empedu mengalami edema. Limpa dan kelenjar getah bening juga mengalami edema dan pteki. Edema kornea pada mata, otak mengalami pteki. Perdarahan (ekimosis) pada mukosa saluran pencernaan. Pemeriksaan histopatologi menunjukkan terdapat badan inklusi intranuklear pada organ hati, ginjal, mata, dan otak, pada hati ditemukan nekrosis hati disertai dengan infiltrasi sel radang. Nefritis interstisial pada ginjal. Uveitis anterior dan degenerasi kornea pada mata, serta proliferasi sel glia pada otak. Gambaran patologi-anatomi dan histopatologi yang menciri ICH adalah hepatitis, edema pada kantung empedu dan badan inklusi intranuklear pada hepatosit serta sel-sel endotel di organ lain. Perlu dikembangkan metode deteksi survei CAV-1 untuk mengetahui prevalensi kasus ICH di Indonesia., Studies on infectious diseases in animals caused by viruses have been carried out in various places in the world. One of the diseases which considered important is Infectious Canine Hepatitis (ICH). ICH is an infectious disease in dogs and can be transmitted to other animals caused by canine adenovirus type 1 (CAV-1). The literature study aims to examine the pathological features of animals infected with ICH and find out which animals are sensitive to it ICH. Animals sensitive to ICH are coyotes, foxes, wolves, brown bears (Ursos arctos), striped skunks (Mephitis mephitis), and beavers (Lutra lutra). The main targets of the CAV-1 virus are endothelial cells and hepatocytes. The main pathomorphological features in organs of animals which infected with ICH are fragile, edematous and slightly enlarged liver. Additionally, there is hemorrhagic infarction of the renal cortex. The lungs and gallbladder walls are often edematous. The spleen and lymph nodes are edematous with petechiae. Corneal edema of the eye, the brain has petechiae. The presence of bleeding (ecchymosis) in the mucosa of the digestive tract. Histopathological examination showed that there were intranuclear inclusion bodies in all affected organs such as in the liver, kidney, eyes and brain. The liver shows liver necrosis accompanied by inflammatory cells infiltration, interstitial nephritis of the kidney, anterior uveitis and corneal degeneration of the eye, along with proliferation of glial cells in the brain. Conclusively, pathological hallmarks of that characterize ICH are hepatitis, edematous gallbladder, and intranuclear inclusion bodies within the hepatocytes and endothelial cells of many organs. It is necessary to develope detection method for surveying CAV-1 to determine ICH prevalency in Indonesia.
Keyword: Dogs, ICH, Pathologic anatomy, Histopathology

Judul: Infeksi alami virus rabies pada anjing: studi morfopatologi dan imunohistokimia
Abstrak: Rabies is a zoonotic disease that remains a big problem in public health sector in Indonesia. The pathomorphological and antigen distribution of street rabies virus infection of the dogs brain from endemic area in Indonesia need for further investigation. The aim of this study was to describe macroscopical, histopathological and antigen distribution of rabid dogs which is infected with rabies virus naturally. Fourteen brains of stray rabid dogs from Disease Investigation Centre Bukittinggi area were used as samples. Conformatory diagnosed based on direct fluorescence antibody technique test. Hyperemic meningeal blood vessels were consistently found in all samples, sometimes associated with multiple ptechie and cerebral edema. Histopathological changes showed mild non-suppuratif meningoencephalitis with perivascullar cuffing surrounded by lymphocyte cells, associated with gliosis. Negri bodies were found in neuron cytoplasms in all samples mainly localized in pyramidal cells of cornua ammons of hippocampus and cerebral cortex, while neuronal degeneration and necrosis were mild. Viral antigens localized in perikaryon extending along the dendrites and axon and mostly localized on pyramidal cells of hippocampus, talamus and frontal lobes of cerebral cortex. Rabies antigen were also detected in epithelial cells of mucogenic acini of mandibulary glands and mildly in granular of striated duct of luminal parotidal glands. This study suggested that frontal lobes of cerebral cortex and mandibulary glands could be used as samples for rabies test in laboratory besides hippocampus.
Keyword: 

Judul: Sintesis Superkonduktor YBCO dengan Metode Evaporasi dan Karakterisasinya
Abstrak: Telah berhasil dibuat pelet superkonduktor YBCO-123 dengan metode evaporasi dengan menghasilkan Tc = 100 K. Sintesis dilakukan dengan mencampur garam-garam nitrat Y(NO3)2, Ba(NO3), Cu(NO3)2 di dalam pelarut H2O pada suhu 150 oC. Setelah melalui proses pirolisis pada 350 oC selama 1 jam, prekursor dikalsinasi pada 900 oC selama 4 jam kemudian serbuk dikompaksi dengan tekanan hidrolik 5 ton untuk membentuk pelet dengan diameter 1,5 cm dan tebal 0,24 mm. Sintering dilakukan pada suhu 940 oC selama 20 jam. Efek meissner menunjukkan fenomena levitasi pada temperatur sekitar 80 K. Hal ini menunjukkan fasa superkonduktor telah terbentuk. Data XRD memberi mengkonfirmasi bahwa fasa kristal 123 telah terbentuk. Nilai konduktivitas didapat dari hasil pengukuran dengan LCR pada temperatur 300 K sebesar 4 x 10-5 S/cm. Pada penurunan temperatur dari 100 K ke 80 K terjadi kenaikan nilai konduktansi yang tajam dari 4.2 x 10-4 S/cm ke nilai 1.309 x 10-1 S/cm.
Keyword: