Judul: Pemberian Ovalbumin Sebagai Penyebab Alergi pada Marmot
Abstrak: Most people consider allergic is not dangerous. However in some cases may cause death. Allergic has been suspected to relate with immunoglobulin E (IgE) formation, followed by the release of histamine and other cells mediator, until the symptom occur. In this research, the effect of ovalbumin induction on allergic reaction was studied. The used guinea pigs were divided into control (K) and ovalbumin treatment groups, each containing three guinea pigs. Animals were adapted for 14 days then 40 days albumin induced for allergic reaction. Guinea pig’s blood were taken after 40 days sensitization and injected back (anafilaksis cutaneous pasif) to the animals. Evans blue were given after 48 hours serum injection, to obtain bluish spot formation for symptom observation. Research showed that ovalbumin induced allergic reaction. Anafilaksis cutaneous passive testing showed that the bluish diameter didn’t occure on guinea pig’s back, but the allergic effect occurred tend to systemic effect.
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Judul: Pengaruh Kuersetin terhadap Derajat Alergi dan Kadar Imunoglobulin E pada Marmot yang Diinduksi Putih Telur
Abstrak: Quercetin is one of flavonoid class which has been clinically proven for allergic and also has been syntheticed. It has not researched yet to determine the smallest which can effect as antiallergic. The guinea pigs divided into two groups, control (K) and Quercetin (Q) groups. Each groups were comprised three guinea pigs and all of it were adapted for 14 days. Guinea pigs were sensitized for 39 days with egg white 2 mg/mL dissolved by Al(OH)3 as adjuvant and buffer saline by forced egg white down. While, another three guinea pigs were adapted for 3 days to determine pharmacologic dosage based Lethal Dose 50 (LD50) of Quercetin. The result of this assay showed that at dose 13.92 mg/kg body weight is safe dosage. This dosage then used for determine the effect of quercetin as antiallergy with Evans blue dye as indicator (AKP method). The result of AKP showed that quercetin has no significant effect. The concentration of Immunoglobulin E (IgE) in guinea pigs serum also same for all guinea pigs < 2.4 ng/mL. The result of this research was quercetin at dose 13.92 mg/kg body weight has no significant effect as antiallergic.
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Judul: Implementasi Space Time Composite (STC) Data Model Menggunakan Model Data Relasional
Abstrak: The data model is a concept that describes the data stored in the database and the relationship between the data to the user in logic. Development of data models is very important in the design of the database as the basis of the stage of database design to be made. This study aims to apply the concept of Space Time Composite (STC) on the Model Data storage vector data types that can store enough information and describes the process of drafting objects and objects spatiotemporal evolution over time. From the results of the test queries on the data model that have been created, queries in a system are acquired that can help display the information preparation of objects from time to time and know the history of the object polygon and arc that has undergone changes in topology.
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