Judul: Studi kemampuan vaksin IBD blend strain winterfield 2512 yang divaksinasikan pada ayam pedaging umur sehari dalam mencegah infeksi virus IBD isolat lapang
Abstrak: The aim of this study was to investigate the efectivity broiler DOC vaccination with IBD Blend vaccine Strain Winterfield 2512 in preventing infection IBDV field isolate. As many as 104 DOC were used in the study. The chickens were divided into two groups, each group consist of 52 DOC. At the first day ten DOC of each group were bleed to collect serum sample. The first group was vaccinated with IBD Blend vaccine Strain Winterfield 2512 throught eye drop at the first day. The second group was unvaccinated server as a control. Serum were collect on day 1st, day 14th, day 28th, and day 42nd. Ten DOC from each group were challenge by IBDV field isolate at day 28th. All samples analyze by indirect ELISA test. The result showed that all the DOC were carried out maternal antibody with protective level i.e 3585 Elisa Unit (EU). The antibody titer of vaccinated group at day 14th increase significantly difference (P<0.05) i.e 4808 EU compare to unvaccinated group i.e 3024 EU, but at day 28th the antibody titer between each group were no significantly difference (P>0.05). After challenge all the vaccinated chickens appear clinical sign and damage of bursa Fabricius while unvaccinated group only showed 80% bursal damage. The result showed that vaccination IBD Blend Strain Winterfield 2512 at the first day was unable to protect the chickens from clinical sign caused by IBD virus infection.
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Judul: Kajian Serologis Dan Molekuler Ayam Pedaging Yang Divaksinasi Menggunakan Vaksin Infectious Bursal Disease (IBD) Berbagai Tingkat Dosis
Abstrak: Disease of Infectious bursal disease (IBD) is a viral disease that causes economic losses to the poultry industry as it causes high mortality and immunosuppression. IBD disease prevention efforts carried out by means of vaccination and biosecurity. IBD vaccination of day old security needs to be investigated its ability to prevent infection. This study aimed to observe the serological response and clinical condition based on examination of molecular actively vaccinated with IBD vaccine at different dose levels of daily life and challenged with virus field isolates. A total of 180 chickens were divided into four groups: K1 (full dose), K2 (½ Dose), K3 (dose ¼) and K4 (Dose 0). The vaccine used was a live IBD vaccine strains intermediate. Observations carried out on five chickens from each group that includes: antibody titers, the ratio bursa weight/bodyweight and pathology images. Presence of field virus infection and the linical condition due to infection challenge was observed by PCR. Observations made on days 1, 7, 28 and 42. Observations showed that the full dose vaccinated chickens started to show positive antibody formation against IBD at day 28 after vaccination, while in chickens vaccinated with a half and a quarter dose positive antibody titers 42 days post-vaccination. Clinical observations showed that vaccinated chickens various dose levels showed the same clinical symptoms than the control group. Similarly to the results of PCR observations it appears that the chickens from the vaccinated group of IBD viruses detected. The results of this study suggest that active IBD day old vaccination is not effective in preventing infection of the field.
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Judul: Penggunaan Teorema Homeomorphy 2-Manifold dan Teorema Euler Poincare pada Torus 𝑇�� dan Simplicial Complex 𝐾��
Abstrak: Two dimensional topological spaces are said to be homeomorphic if they have the same topological invariant, where one of topological invariant used is an Euler characteristic. Homeomorphy 2-Manifold’s Theorem and Euler Poincare’s Theorem are used to distinguish two topological spaces. Homeomorphy 2-Manifold’s Theorem uses Euler characteristic to identify two dimensional topological spaces. Euler Poincare’s Theorem is an alternative way to find Euler characteristic with Betti number, which is topological invariant as well. The objective of this paper is to investigate the homeomorphism of torus 𝑇����� and simplicial complex 𝐾�����. Topological space torus and simplicial complex 𝐾����� have the same Euler characteristic, which is two. Based on Homeomorphy 2-Manifold’s Theorem topological space torus 𝑇����� and simplicial complex 𝐾����� is homeomorphic.
Keyword: simplicial, torus, Euler, homeomorphism, topology