Judul: Uji Aktivitas Antikanker Ekstrak Kemedangan Pohon Penghasil Gaharu Hasil Inokulasi
Abstrak: The phytochemical contents and anticancer activities of kemedangan from agarwood-producing trees inoculated with fungi have been studied to increase the utility value. The simplicias were macerated in n-hexane to remove triglycerides, and the residues were further macerated in ethyl acetate and methanol, respectively. Phytochemical test on ethyl acetate and methanol extracts showed the same results, but with different quantities. Toxicity test with brine shrimp showed that all samples were potential as active compounds and the lowest 50% lethal concentrations were shown by ethyl acetate extract of uninnoculated Aquilaria microcarpa and methanol extract of inoculated A. microcarpa, 18.77 and 44.01 ppm, respectively. In vitro anticancer test of methanol extract from inoculated A. microcarpa showed 50% inhibition concentration value of 298.53 ppm, much higher than the commercial anticancer drug, doxorubicin. Based on these results, both extracts were not potential as anticancer.
Keyword: agarwood, anticancer, kemedangan, phytochemical, toxicity

Judul: Toksisitas dan Aktivitas Antioksidan Ekstrak Daun Pohon Penghasil Gaharu Hasil Inokulasi
Abstrak: Gaharu leaves are expected to contain many secondary metabolic compounds as a response against fungal infection on gaharu-producing trees. This study aimed to determine the phytochemical components, cytotoxic and antioxidant activities of Aquilaria microcarpa and A. malaccensis leaves with and without fungal inoculation. Gaharu leaves were extracted by using methanol. The phytochemical assay of the crude extract revealed the presence of tannins, steroids, phenols, and flavonoids. The toxicity evaluation with brine shrimp showed that all samples were potencial as active ingredient, but only the juvenile leaves of A. microcarpa inoculated by fungi from Papua and Gorontalo had the potency as anticancer due to their LC50 value < 30 μg/mL. Free radical scavenging activity of the extracts against 2,2-diphenyl-1-picrylhydrazyl showed strong antioxidant activities with IC50 value of < 200 μg/mL. The highest antioxidant activity was exhibited by juvenile leaves of A.microcarpa inoculated by fungi from Timor and uninoculated mature leaves of A. malaccensis.
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Judul: Pembuatan Film Tipis Lithium Niobat (LiNbO3) Menggunakan Metode Chemical Solution Deposition (CSD) dengan Variasi Kecepatan Putar (Rpm).
Abstrak: Film tipis merupakan salah satu aspek yang mendapat perhatian sangat besar dalam bidang material, karena film tipis merupakan material menarik yang memiliki sifat optik yang sangat tergantung pada konstanta dielektrik, indeks bias, dan energi gap. Lithium Niobat (LiNbO3 ) dapat digunakan sebagai pelapis pada film tipis karena memiliki sifat piezoelektrik, electrooptical, pyroelectrical dan photorefractive yang sangat baik. Film tipis Lithium Niobat (LiNbO3 ) ditumbuhkan menggunakan metode Chemical Solution Deposition (CSD) dengan variasi kecepatan 3500 rpm, 5000 rpm, 6500 rpm, dan 8000 rpm. Metode ini memiliki keunggulan dapat mengontrol stokiometri film tipis dengan kualitas yang baik, prosedur yang mudah dan membutukan biaya yang relatif murah. Energi band gap yang dihasilkan dari film tipis Lithium Niobat (LiNbO3) berkisar antara rentang 2.1 eV – 2.8 eV dengan indeks bias berada pada rentang 2.18-3.2. Film tipis LiNbO3 memiliki parameter kisi a=b=5.54Ǻ dan c = 16.35 Ǻ. Struktur morfologi film tipis adalah permukaan yang homogen dan ukuran kristal berada pada rentang 0.417 μm – 0.680 μm.
Keyword: sifat optik, litium niobat, chemical solution deposition, kecepatan putar