Judul: Potensi Ekstrak Buah Makasar (Brucea javanica (L.) Merr) sebagai Antihipertensi
Abstrak: It is believed that people like to consume fatty and salty food which lead to hypertension. They used antihypertensive drug to control hypertension, however, intolerant side effects could appear. It brings them to find another healing like Indonesian herbs. The aim of this research was examine the antihypertensive potency of aqueous and hexane fraction of brucea fruit. This research used 2 months old Sprague Dawley male rats which hypertensived by adrenaline injection. The ripe brucea fruit was used in this research. At the beginning, researcher oriented the respon time of samples. Systolic blood pressure was measured by indirect method. It used bisoprolol’s dose which is 0.0714 mg/kg body’s weight as antihypertensive agent standart to samples as well. Hexane and aqueous fraction then bisoprolol achieved hypotension at minute 20th, 60th, and 80th via oral. Hypertensive effect of adrenaline was achieved at minute 20th via intraperitoneal. Both hexane and aquoeus fractions had antihypertensive potency because of its ability to decrease the raising of systolic blood pressure due to adrenaline about 27.66% and 34.40% higher than standart about 11.65%.
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Judul: Aktivitas antihiperglikemia fraksi air buah makasar (Brucea javanica (L.) Merr) pada tikus yang diinduksi aloksan
Abstrak: Brucea fruit (Brucea javanica (L.) Merr) was known to have a potential antidiabetic activity. This research was aimed to determine antihyperglycemic activity of aqueous fraction from ethanolic extract of brucea fruit in alloxan induced rats. Aqueous fraction of ethanolic extract brucea fruit obtained by maseration using ethanol 95%, which then separated using funnel separator with mixed solution of hexane, methanol, and water (5:9:1) and chloroform:water (1:1). Twenty four rats divided into 6 groups. In the process of raising the blood glucose concentration, one of normal group induced by NaCl 0.9% and the other five treatment groups induced by alloxan (150 mg/kg BW). Afterwards, in the treatment process, normal group and negative control administered by aquadest, positive control administered by glibenclamid (0.25 mg/kg BW), and three other groups administered by aqueous fraction of ethanolic extract brucea fruit in dosage 0.25, 25, and 50 mg/kg BW. Blood glucose concentration of the fasting rats measured at day 0, 3,7,11, and 15. Aqueous fraction from ethanolic extract of brucea fruit contained 3.71% in yield. The result showed that aqueous fraction from ethanolic extract of brucea fruit in dosage 0.25, 25, dan 50 mg/kg BW decreased the blood glucose concentration as many 37.64%, 37.43%, and 60.82% respectively. Aqueous fraction of brucea fruit wich is extracted by ethanol in dosage 50 mg/kg BW has higher activity than glibenclamid in dosage 0.25 mg/kg BW (45.53%).
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Judul: igenvalues and Eigenvectors of Tridiagonal Matrix with Non Constant and Recurrent Diagonal Entries.
Abstrak: Matriks tridiagonal adalah suatu matriks yang mempunyai entri-entri bernilai nol kecuali pada diagonal utama, di bawah diagonal utama (subdiagonal) dan di atas diagonal utama (superdiagonal). Entri pada diagonal utama tidak konstan dan berulang. Setiap entri pada matriks tridiagonal ini adalah bilangan kompleks. Dalam karya ilmiah ini, akan dibuktikan 3 teorema untuk menentukan nilai eigen dengan 2 kasus dan 1 teorema untuk menentukan vektor eigen. Teorema pertama menentukan polinomial karakteristik dari matriks tridiagonal. Polinomial karakteristik dari matriks tridiagonal tersebut digunakan untuk menentukan nilai eigen pada teorema kedua dan ketiga serta menentukan vektor eigen pada teorema keempat
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