Judul: Gambaran histopatologi usus halus ayam petelur yang diberi ekstrak etanol temulawak [Curcuma xanthorrhiza Roxb]
Abstrak: The objective of this research is to elaborate the effect of temulawak (Curcuma xanthorriza Roxb.) ethanol (70% and 96%) extracts on the histopatological lesions of chicken’s small intestines. Eighty heads of 16 weeks old laying hens were divided into eight groups with various treatments. The treatments were, (1) 17.5 mg temulawak ethanol (70%) extract /kg BW, (2) 35 mg temulawak ethanol (70%) extract / kg BW, (3) 52.5 mg temulawak ethanol (70%) extract / kg BW, (4) 17.5 mg temulawak ethanol (96%) extract / kg BW, (5) 35 mg temulawak ethanol (96%) extract / kg BW, (6) 52.5 mg temulawak ethanol (96%) extract / kg BW, (7) commercially meniran (Phylantus niruri) extract as positive control (Stimuno®) and (8) untreated as negative control. Treatments were given for 4 weeks with 3 days rest on each week. In the end of the treatments all birds were necropsied. The small intestines were collected and processed for histopatological slides using Hematoxylin Eosin and Periodic Acid Schiff staining and examined using a light microscope and video micrometer. Observation showed that temulawak ethanol extracts didn’t give significant effect on the amount of the villi as well as epithelial cells intact; but temulawak ethanol extracts increasing the amount of Lieberkuhn crypts of small intestines. Temulawak ethanol extracts increasing the height of jejunum and ileum’s villi and also the number of jejunum’s goblet cells. Gut Associated Lymphoid Tissue (GALT) in duodenum and ileum were also increased in the temulawak ethanol extract groups. The assay results indicated that temulawak ethanol extracts did not toxic for the intestines and could improve the chicken’s non spesific immune response. Keyword: temulawak (Curcuma xanthorriza Roxb.), small intestines, chicken, histopathology, ethanol extract
Keyword: Temulawak, Curcuma xanthorrhiza Roxb, Small intensitas, Chicken, Histopathology, Ethanol extract, IPB, Temulawak

Judul: Pengaruh pemberian ekstrak etanol temulawak [Curcuma xanthorrihiza Roxb.] pada gambaran histopatologi hati ayam petelur strain ISA Brown
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol temulawak terhadap gambaran histopatologi organ hati ayam. Sebanyak 80 ekor ayam petelur strain ISA Brown yang dibagi menjadi 8 kelompok yaitu: kelompok ekstrak (70% etanol) 17,5 mg/kg BB, 35 mg/kg BB, dan 52,5 mg/kg BB; kelompok ekstrak (96% etanol) 17,5 mg/kg BB, 35 mg/kg BB, dan 52,5 mg/kg BB; kontrol positif yang diberi ekstrak meniran (Phyllanthus niruri) komersial (Stimuno): dan kontrol negatif yang tidak diberikan ekstrak temulawak maupun ekstrak meniran. Perhitungan dilakukan melalui pengamatan histopatologi dan pengolahan data menggunakan uji analisis sidik ragam (ANOVA). Parameter yang diamati adalah jumlah sel nekrotik, jumlah sel apoptosis, jumlah sel Kuppfer serta perubahan-perubahan lainnya yang terjadi pada hati, termasuk degenerasi lemak. Pengamatan histopatologi organ hati menunjukkan bahwa terjadi peningkatan jumlah sel apoptosis dalam jumlah kecil dan penurunan degenerasi lemak terjadi pada semua dosis ekstrak dengan aktivitas tertinggi pada dosis 52,5 mg/kg BB dengan pelarut 96% etanol, sedangkan penurunan jumlah sel nekrotik serta peningkatan jumlah sel Kupffer tertinggi pada dosis 35mg/kg BB dengan pelarut 96%. Berdasarkan hasil tersebut, dapat disimpulkan bahwa ekstrak etanol temulawak bersifat tidak toksik pada sel hati dan temulawak bersifat sebagai hepatoprotektor….
Keyword: Liver, Curcuma xanthorrhiza, Hepatoprotector, Histopathology, Ethanol

Judul: Metrik Einstein (Anti-) Self-Dual Berdimensi Empat dengan Metode Cartan
Abstrak: Gravitational field equation can be formulated in differential forms (differential geometry), which describes gravity as a manifestation of the curvature of space-time. Curvature of space-time is characterized by a metric that satisfies the gravitational field equation. With differential forms it can be formulated the (anti-) self-dual Einstein equation, which is a modification of the Cartan structure in (anti-) self-dual basis. Calculation of (anti-) self-dual metric with (anti-) self-dual Einstein equation is simpler than the calculation using Christoffel symbols.
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