Judul: Maximum difference scaling pada pengukuran preferensi siswa SMA Kota Bogor dalam memilih perguruan tinggi
Abstrak: Metode yang bisa digunakan pada teknik penskalaan untuk studi sikap yang berhubungan denagn tingkat kesukaan (preferensi ) mempunyai beberapa kelemahan sehingga hasil penelitian tidak memeberikan manfaat yang maksimal bagi peneliti. Maximum Difference Scaling (maxdiff) adlah teknik pengukuran dan penskalaan yang dianggap mampu mengatasi kekeurangan pada metode skala peringkat (ranking scales), metode skala penilaian (rating scales), danmetode pembandingan berpasangan (paired comparison).
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Judul: Perbedaan pola prestasi siswa SMA dan kaitannya terhadap pilihan perguruan tinggi dan program studi yang diminati
Abstrak: Penjurusan di SMA bertujuan untuk mengelompokkan' siswa berdasar minat, bakat dan kemampuan, dan dianggap menjadi suatu hal yang penting karena dimaksudkan untuk memberi bekal kemampuan yang diperlukan di perguruan tinggi. Pada kenyataannya banyak siswa Jurusan A1 dan A2 melanjutkan studi ke Sains Sosial. Tujuan penelitian ini adalah melihat penyebaran siswa SMA ke perguruan tinggi serta jurusannya, dengan penekanan melihat siswa peminat ke Sains/Pertanian dan Teknik/Kedok- teran di PTN unggulan. Data yang digunakan adalah data primer yang diperoleh dari angket siswa di dua buah SMA, dengan obyek pengamatan siswa klas 2 dan klas 3. Dari hasil plot rataan peubah penentu terhadap pilihan perguruan tinggi diperoleh hasil bahwa siswa terbaik di kedua SMA cenderung memilih ke PTN unggulan sebagai tempat studinya. Hasil plot rataan peubah penentu terhadap pilihan jurusan, menunjukkan bahwa antara siswa peminat ke Teknik/Kedokteran dan Sains/Pertanian tidak terdapat perbedaan prestasi yang cukup jelas. ...
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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