Judul: Profil Hematologi Mencit pada Implantasi Biomaterial Logam Berbahan Dasar Besi
Abstrak: Biomaterials are certain materials that are inserted into the body and used as a medical device that interacts with the body's tissues and fluids. The aim of this study was to determine the effect of implantation of iron based metal biomaterials to blood hematological profile, including the erythrocyte count, hemoglobin concentration, hematocrit value, leukocyte count and leukocyte differentiation. This study used 40 mice. The mice were divided into 4 groups, the iron wire group (Fe, n = 12), chromium-coated iron wire (Fe-Cr, n = 12), stainless steel surgical wire (316L SS, n = 12) and the control group (n = 4). Mice implanted with metal biomaterials in the hip area subcutaneously and in thigh area intramuscularly. Blood sampling performed on days 0, 1, 4, and 14 after implantation of biomaterials, through the retro-orbital sinus using microhematocrit tube. Implantation of iron based metal biomaterial not caused significant changes to erythrocytes count, hemoglobin levels, hematocrit values lymphocytes, eosinophils, and basophils. Leukocyte count, percentage of neutrophils, and percentage of monocytes in all groups of mice were significantly increased on day 1 (p<0.05), but on days 0, 4, and 14 showed the values that are not significantly different (p> 0.05). Generally, the implantation of iron based metal biomaterial not caused significant changes to red blood cell and white blood cell’s profiles.
Keyword: subcutaneously, mice, iron based metal implant, intramuscularly, hematology

Judul: Pengamatan Makroskopis Biodegradasi Implan Logam Berbahan Dasar Besi pada Mencit
Abstrak: Biodegradation of metal implants is metal corrosion process due to the reaction between the metal with the substances in the environment, especially the environment of the body. The aim of this study is to examine the biodegradation behavior of iron based metal implants in mice. This study used 40 adult male ddy mice 30-35g. Mice were divided into 4 groups, Fe (iron wire) n=12, Fe-Cr (iron coated by chromium) n=12, SS 316L (stainless steel) n=12, and control (n=4). The implantation of materials was placed the hip area/intramuscularly (IM) and thigh area/subcutaneously (SC). Macroscopic study of biodegradation iron based metal implants were material changes examination, evaluation of carat formed, the corrosion rate, and the weight loss. The result showed the greatest damage occurred in Fe, followed by Fe-Cr and last a relatively no damage is SS 316L implant. The subcutaneously implanted material suffered higher damage than the intramuscularly implanted material. The greatest corrosion rate occurred in Fe implant. The corrosion rate of Fe-Cr lower than Fe implant (P<0.05) at the first time of implantation. The weight loss of Fe not significantly differ (P>0.05) as the weight loss of Fe-Cr at the first time of implantation, but its lower than the weight lose of Fe-Cr implant (P<0.05) at the last time of implantation. SS 316L implant not showed the corrosion rate and the weight loss. As a conclusion , Fe and Fe-Cr implants were potentially as implant materials that can be degraded and therefore could be use for medical applications.
Keyword: mice, iron based metal implant, biomaterial, biodegradable

Judul: Peranan Jasa Transportasi dalam  Menunjang Pembangunan Wilayah  Kaitannya dengan Pelaksanaan  Otonomi Daerah di Provinsi Papua  Khususnya Kabupaten Jayapura
Abstrak: Ketimpangan pembangunan yang terjadi selama Orde Baru telah memicu disintegrasi bangsa, salah satu daerah yang diisukan terancam disintegrasi sebagai akibat ketimpangan pembangunan pada reszim orde baru adalah Provinsi Papua, sehingga untuk meredam aspirasi disintgrasi, dimasa reformasi Provinsi Papua ditetapkan sebagai daerah yang menerima Otonomi Khusus. Dengan adanya otonomi khusus ini diharapkan pemerintah daerah lebih leluasa mengabil kebijakan yang disesuaikan dengan aspirasi dan prioritas permasalahan yang dihadapi masyarakat.
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