Judul: Pengaruh Konflik Pernikahan dan Komunikasi Orang Tua-Anak terhadap Kepribadian Remaja pada Keluarga Ibu Bekerja dan Keluarga Ibu Tidak Bekerja
Abstrak: The increasing of Labor Force Participation Rate shows that there are many families who have working mothers and contribute directly to double-burdens problem. The problem of double-burden also affects on family life. This research was aimed to analyze the correlations between marital conflict, parent-child communication, and teenager’s maladjustment of working and non-working mother families. The research was conducted at Subdistrict Tanah Sareal, Bogor City by undertaking two areas, i.e Kebon Pedes and Kedung Badak. The research involved 100 families wich were selected by random that were derived from working mothers group and non working mothers group. Respondents of this research were mother and 12-15 years old teenage children. The data collection was carried out by interviewing mother and her teenager using structural quetionnaires. The data were analyzed by descriptive and inferensia analysis. The results showed significant relationship between family’s characteristic, teenager’s characteristic, and marital conflict and teenager’s personality. Significant correlations also found between marital conflict, parent-child communication and teenager’s personality. The results showed teenager’s characteristic and parent-child communication influence on teenager’s personality (maladjustment personality). The strenght of linear correlations and are discussed.
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Judul: Gaya Pengasuhan Ibu, Kelekatan dengan Teman Sebaya, dan Konsep Diri Remaja pada Keluarga Ibu Bekerja dan Tidak Bekerja
Abstrak: The aims of this study was to analyze the influence of parenting style of mother and peer attachment on adolescent’s self-concept. Sample of this research were the families with working and nonworking mother had teenager child which is aged 12-15 years who lived in Kebon Pedes and Kedung Badak Village, Tanah Sareal, Bogor City. There were 100 families selected randomly consisting of 50 working mother families and 50 nonworking mother families that were interviewed by questionnaire. The result of corellation test showed there were significant relationships between gender, age of parents and adolescents, family’s income, authoritative parenting, authoritarian parenting, permissive parenting, and peer attachment with adolescent’s self concept. Based on regression test, it was found that variables influenced adolescent’s self concept were adolescent’s allowance, families’s socio-economic, authoritative parenting style, and peer attachment.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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