Judul: Pengaruh Penambahan Ekstrak Etanol Temu Ireng (Curcuma Aeruginosa Roxb.) Terhadap Pertumbuhan Sel Lestari Tumor Mca-B1 Dan Mcm-B2 Secara In Vitro
Abstrak: Penelitian ini bertujuan untuk mempelajari kemampuan penghambatan ekstrak etanol temu ireng terhadap pertumbuhan sel lestari tumor MCA-B1 dan MCM-B2. Penelitian dilakukan dengan menanam sel lestari tumor MCA-B1 dan MCM-B2 pada tissue culture plate 24 well dengan konsentrasi ekstrak yang berbeda sebanyak 3 kali ulangan. Konsentrasi ekstrak yang dipakai adalah 0 ppm sebagai kontrol negatif (tidak diberi penambahan ekstrak), doxorubicin 100 ppm sebagai kontrol positif, 12.5 ppm, 25 ppm, 37.5 ppm, 50 ppm. Setelah sel lestari tumor pada lubang kontrol negatif konfluens, sel dipanen dan dihitung menggunakan kamar hitung hemositometer Neubauer dengan pewarnaan trypan blue. Sel lestari diinkubasi pada suhu 37oC, 5% CO2. Hasil penelitian menunjukkan adanya aktivitas antiproliferasi ekstrak etanol temu ireng yang berbeda nyata p(<0.05) terhadap kedua sel lestari tumor MCA-B1 dan MCM-B2. Dosis ekstrak yang menunjukkan hasil paling baik adalah 50 ppm dengan aktivitas antiproliferasi sebesar 80.59% pada sel lestari tumor MCA-B1 dan 84.33% pada sel lestari tumor MCM-B2. Hasil tersebut menunjukkan potensi temu ireng sebagai tanaman yang memiliki aktivitas sebagai anti tumor.
Keyword: antiproliferasi, ekstrak temu ireng, MCA-B1, MCM-B2, sel lestari

Judul: Efek Pemberian Ekstrak Etanol Temu Ireng (Curcuma Aeruginosa Roxb.) pada Proliferasi Sel Lestari Tumor THP1 dan A549 Secara In Vitro.
Abstrak: The use of plant extracts is one of alternative ways to heal tumor diseases. The purpose of this research is to study the effect of ethanol extract of temu ireng (Curcuma aeruginosa Roxb.) on proliferation of THP1 and A549 cell lines. The extract concentration used were 0 ppm (as a negative control), 12.5 ppm, 25 ppm; 37.5 ppm and 50 ppm, doxorubicin as a positive control, and the treatment were in three replications. All data were analyzed statistically by ANOVA and Duncan test. The results showed that inhibition activity of temu ireng ethanol extract on THP1 and A549 cell line proliferation were significantly different (p<0.05) than negative control. Inhibition activity were as higher as treatment dose and significantly different (p<0.05) between dose, except 25 ppm and 37.5 ppm dose on THP1 cell line. The highest inhibition was achieved at 50 ppm dose as 85,8% for THP1 cell line and 73.3% for A549 cell line. Based on this results, we concluded that temu ireng ethanol extract has a poliferation inhibition activity on both cell lines and has a potential substance to be develop as antitumor.
Keyword: A549, curcuma aeruginosa Roxb, inhibition activity, THP1

Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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