Judul: Pengaruh pemberian beta glukan dari Saccharomyces cerevisiae terhadap kadar LDL dan HDL darah tikus putih
Abstrak: Beta glukan merupakan rantai panjang polisakarida yang tersusun oleh monomer glukosa dengan ikatan glikosida. Salah satu sumber beta glukan adalah dinding sel Saccharomyces cerevisiae dalam bentuk beta 1,3 glukan dan beta 1,6 glukan. Salah satu manfaat beta glukan adalah dapat menurunkan kadar kolesterol. Dalam penelitian ini dilakukan bioassai beta glukan terhadap tikus putih yang diinduksi dengan pakan kolesterol 1.5 %. Percobaan dilakukan selama 21 hari dan dilakukan pengukuran terhadap kadar kolesterol total, HDL-kolesterol, LDL-kolesterol, dan trigliserida. Hasil ekstraksi beta glukan dari dinding sel S. cerevisiae, kultur sel S. cerevisiae ragi roti menghasilkan beta glukan tertinggi sebesar 1.32 g/L dibandingkan kultur sel S. cerevisiae ragi tape menghasilkan beta glukan sebesar 1.15 g/L. Hasil analisis kadar glukosa dalam sampel beta glukan dari S. cerevisiae ragi roti menggunakan spektrofotometer UV-Vis menghasilkan kadar tertinggi sebesar 26661.40 ppm diikuti beta glukan ragi tape sebesar 1566.95 ppm, dan beta glukan industri sebesar 185.75 ppm. Hasil analisis kadar protein dalam sampel beta glukan dari S. cerevisiae, ragi tape menghasilkan kadar protein yang paling tinggi sebesar 1066.33 ppm, diikuti beta glukan ragi roti sebesar 586.37 ppm, dan beta glukan standar sebesar 83.72 ppm. Tikus yang dicekok beta glukan baik yang berasal dari ragi tape, ragi roti, dan glukan standar sebanyak 1ml/200 g bobot badan setiap hari memperlihatkan penghambatan terhadap naiknya kadar kolesterol dibandingkan kelompok tikus yang diberi pakan kolesterol yang sama tanpa diberi beta glukan (kontrol positif). Beta glukan mampu menekan naiknya kadar LDL-kolesterol dan trigliserida serta dapat meningkatkan kadar HDL-kolesterol pada pengukuran hari ke-14, dan 21.
Keyword: 

Judul: Aktivitas antioksidan dan antihiperkolesterolemia eksuak beta glukan dari Saccharomyces cerevisiae pada tikus putih
Abstrak: The effect of beta glucan extract on total cholesterol level, trigliseride and lipid peroxide were studied in male white rat. The animals had been divided into five groups of treatments which contained six rats in every group : the first group was the rat with normal cholesterol, the 2" had hypemholestemlemia control (20 g/kgBW/day), the 3" group had extract beta glucan from Saccharomyces cerevisiae which isolated from bakers yeast treatment, the 4" group have the same beta glucm treatment yeast of '?ape'' origin and the last group had standard beta lucan treatment ti (1 mg/kgBW/day). Hypercholesterolernia condition reached on day 21 , aRer having been induced with PTU and fed by cholesterolic foods. Cholesterol of hypercholesterolemia control group increased up to 209% compared with the baseline values. The rat weight was increased 13% after treatment. All treated samples had significantly reduced blood lipid peroxide level between 8-50% lower than hypercholesterolemia control group(P<0.05). The hypocholesterolemia effect from the three extracts was revealed on day 2 1' to 28h with significant blood cholesterol reduction (6247%) which were lower than the hypercholesterolemia group (p<0.05). The beta glucan extract the from thee isolates codd repress the increased level of blood cholesterol 20-28% lower than hyperchotesterolemia control group, but it seemed not to be consistent because they could only repress the increasing level by day 7' dan 2gh (pAI.05). At the end of hypercholesterolemia induction the level of cholesterol and trigliseride returned into normal conditions. On this circumstances, the hypercholesterolemia effect of the three isolates was revealed. At the end of research, antioxidant activities of the three extracts was able to reduce the liver lipid peroxide level significantly between 3 1-34% lower than the hypercholesterolemia control group.
Keyword: 

Judul: Analisis pemanfaatan ruang wilayah pesisir dalam pelaksanaan otonomi daerah di kabupaten Buru, Maluku
Abstrak: Buru regency as one of the newest region in Moliccas province, as the implementation on decentralization laws, have a big potential in development and management of their coastal zone.
Keyword: