Judul: Simulasi Dinamika Molekul Protein 1GB1 Menggunakan Not Just Another Molecular Dynamcs Program (NAMD)
Abstrak: Protein 1GB1 helps Streptomyces griseus to avoid host defense by immunoglobulin binding site properties. The aim of this study are to learn the mechanism of unfolding and molecular dynamics of protein 1GB1 by temperature variance based on some parameters. Coordinate file of 1GB1 that given by NMR (Nuclear Magnetic Resonance) can be downloaded from Protein Data Bank, then it was processed by some steps such as minimization, heating, equilibration and production run using PBC (Periodic Boundary Condition) and PME (Particle Mesh Ewald) methods. Simulation running at 325K, 350K, 375K, 400K, 450K dan 500K. Except simulation 1 ns at 500K, all simulations running for 10 ns. Some parameters shown unfolding process of 1GB1 at 900 ps in 500 K simulation. Secondary structures that broke for the first time is alpha-helix that converted to turn and coil.
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Judul: Analisis Kestabilan Protein 1GB1 Menggunakan Simulasi Dinamika Molekul
Abstrak: A mechanism to explain the stability of the protein is still a major problem that is not fully understood. One of the problem is understanding the high thermal stability of 1GB1 protein. The thermal stability of 1GB1 protein can be analyzed using molecular dynamics simulation technique. The aim of this research is to learn molecular dynamics and thermal stability of 1GB1 protein in the range of simulation up to 100 ns. Simulation process consists of the preparation, minimization, heating, equilibration, and production run. The initial coordinate file 1GB1 can be downloaded from Protein Data Bank. The influence of thermal that given by this simulation are 450K and 475K for 100 ns, while 500K is bounded for 2 ns. For 475K simulation, the unfolding process occured at 95 ns indicated by the dissappearance of some secondary structure. For 500K simulation, the unfolding process occured at 745 ps indicated by the dissappearance of most of the secondary structure (collapsing of α-helix and β-hairpin structure).
Keyword: unfolding, thermal stability, 1GB1 protein, molecular dynamics simulation

Judul: Bird Trade Via E-commerce in Indonesia
Abstrak: Kemajuan teknologi mempermudah perdagangan satwa liar, termasuk burung. Penelitian ini mengidentifikasi jenis burung yang diperdagangkan, mengkategorikan produk yang dijual, kota dan kabupaten di Indonesia yang paling banyak menjual, serta menduga nilai ekonomi burung yang diperdagangkan secara daring melalui e-commerce. Pengumpulan data dilakukan selama 4 bulan melalui web scraping dengan mengumpulkan informasi seperti nama toko, barang yang dijual (perlengkapan, obat, awetan satwa, aksesoris, dan replika burung), asal, dan barang yang terjual. Berdasarkan hasil penelitian terdapat 411 jenis burung yang dijual dengan pembagian 211 jenis burung Indonesia dan 161 jenis burung asing di 32 daerah di Indonesia. Ordo Passeriformes menjadi jenis burung dominan dengan total penjualan 152 jenis burung endemik dan 69 jenis burung asing. Hasil analisis menunjukkan terdapat 47 jenis burung dilindungi oleh permen LHK No. 106 Tahun 2018, 32 jenis burung masuk kategori IUCN (8 VU, 16 EN, dan 8 CR), serta 66 jenis burung masuk status konservasi CITES (12 App. I, 49 App. II, dan 5 App. III). Total ekonomi yang didapatkan adalah Rp2.079.824.611 dari tahun 2015 hingga 2023., Technological advances make it easier to trade wild animals, including birds. This research identifies the types of birds traded, categorizes the products sold, the cities and districts in Indonesia that sell the most, and estimates the economic value of birds traded online through e-commerce. Data collection was carried out for 4 months via web scraping by collecting information such as shop name, goods sold (equipment, medicine, preserved animals, accessories, and bird replicas), origin, and goods sold. Based on the research results, there are 411 types of birds for sale, divided into 211 types of Indonesian birds and 161 types of foreign birds in 32 regions of Indonesia. The Passeriformes order is the dominant bird species, with total sales of 152 endemic bird species and 69 foreign bird species. The analysis results show that there are 47 bird species protected by LHK regulation no. 106 of 2018, 32 bird species are included in the IUCN category (8 VU, 16 EN, and 8 CR), and 66 bird species are included in CITES conservation status (12 App. I, 49 App. II, and 5 App. III). The total economic gain is IDR 2.079.824.611 from 2015 to 2023.
Keyword: burung, nilai ekonomi, perdagangan