Judul: Profil Kimiawi dari Formulasi Ekstrak Meniran, Kunyit, dan Temulawak Berdasarkan Aktivitas Antioksidan Terbaik
Abstrak: Indonesia is known as a megabiodiversity countries with the title because it has such biodiversity of flora and fauna. Flora or plant widely used as medicine by traditional means, namely phyllanthin, curcuma, and turmeric. Phyllanthin, curcuma, and turmeric extracts are the plant extracts which contains antioxidant activity. This study aimed to evaluate the antioxidant activity of the formulation phyllanthin, turmeric, and curcuma. Phyllanthin, curcuma, and turmeric is extracted using 96% ethanol and extract formulation carried M:K:T ratio of 1:1:1, 1:1:0, 1:0:1, 0:1:1, 1:0 : 0, 0:1:0, and 0:0:1. Extract formulation phyllanthin: curcuma: turmeric (M:K:T) tested the antioxidant activity with DPPH method. Extracts formulation of which have the highest antioxidant activity of the chemical profile was analyzed by TLC and FTIR. Antioxidant activity which have the highest to explained from extract formulation M:K:T = 1:0:0, 1:1:0, dan 1:0:1 by IC50 percentage antioxidant activity are 33.42 ppm, 45.52 ppm, dan 57.65 ppm. TLC chromatogram profiles obtained from formulations M:K:T = 1:1:0, 1:0:1, and 1:0:0 showed the number of spots as much as 10, 8, and 7 spots. FTIR spectrum results showed functional groups of O-H stretching, C-H stretching, C=C stretching and C=C bending in each formulation which have the highest antioxidant activity.
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Judul: Profil kimiawi dari formula ekstrak meniran, kunyit, dan temulawak berdasarkan toksisitas terbaik
Abstrak: Phyllantin, turmeric and curcuma that known have antioxidant, antitumor, anticancer, and antibacterial activity. They are commonly used as single extract. Mixing two components of medicinal plant extracts can increase the bioactivity. The aim of this research was to know toxicity of phyllantin, turmeric and curcuma through Brine Shrimp Lethality Test and to know the profiles of TLC and FTIR that formula. Phyllantin, turmeric and curcuma was extracted with ethanol. Extract was made into seven formulation with 1:1:1; 1:1:0; 1:0:1; 0:1:1; 1:0:0; 0:1:0; 0:0:1 compilation. Toxicity of formulation was known through Brine Shrimp Lethality Test. Three best extract with the lowest LC50 were taken to define their chemical’s profile using TLC and FTIR. The best three extract were phyllantin:turmeric:curcuma in 0:0:1, 0:1:0, and 0:1:1, with LC50 17.94567, 20.09533, 37.66333 ppm, respectively. Phyllantin:turmeric:curcuma in 0:0:1 show TLC profile with thinner spot and without C=O bond for FTIR spectrum as the other two exctract have thick spot and have C=O bond.
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Judul: Implementation of Spatio-Temporal Change Query in Relational Database.
Abstrak: Geographic object changes in various views. Object changes are recorded using a model of static storage. No historical connection between old version data and new version data has been built. For that, a storage model of spatio-temporal queries that can analyze spatio-temporal changes has been developed. The object changes the geometry are grouped according to the taxonomy of Spatio-Temporal Pattern Change. This research has been able to apply the query patterns change including born, expand, merge, contract, split, normal and die. This query based on geometric (area) changes. The implementation of spatio-temporal change queries represents an object changes continuously with easy, change detection is done by comparing two versions of data. Keyword: spatio-temporal change query, spatio-temporal change pattern.
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