Judul: Adaptation of Farmers in Facing Climate Change Based on Social Learning Theory (Case: Farmers Association Responding to Climate Change, Indramayu Regency, West Java)
Abstrak: Krisis iklim yang terjadi saat ini memberikan dampak yang besar bagi sektor pertanian, sehingga perlu adanya adaptasi petani dalam melakukan budidaya pertanian untuk meminimalisir terjadinya kegagalan panen akibat perubahan iklim. Berkaitan dengan hal tersebut terdapat suatu teori yang memandang bahwa perilaku seseorang dapat dipengaruhi oleh model atau lingkungannya yaitu teori pembelajaran sosial. Teori pembelajaran sosial menjelaskan mengenai hubungan antara faktor kognitif, faktor lingkungan, dan perilaku individu. Penelitian ini bertujuan untuk menganalisis perilaku adaptasi petani dalam menghadapi perubahan iklim berdasarkan dua faktor yaitu lingkungan dan kognitif. Penelitian ini menggunakan pendekatan kuantitatif yang diperoleh melalui survey dengan kuesioner serta di dukung data kualitatif yang diperoleh melalui wawancara mendalam kepada informan dan observasi di lapangan. Hasil penelitian menunjukkan bahwa terdapat hubungan antara faktor lingkungan petani dengan faktor kognitif petani, faktor lingkungan dengan perilaku adaptasi petani, serta faktor kognitif dengan perilaku adaptasi petani dalam menghadapi perubahan iklim., The current climate crisis has a major impact on the sector, so it is necessary to adapt farmers in agricultural cultivation to minimize crop failure due to climate change. In this regard, there is a theory which views that a person's behavior can be influenced by the model or the environment, namely the theory of social learning. Social learning theory explains the interrelationships between cognitive factors, environmental factors, and individual behavior. This study aims to analyze the adaptation behavior of farmers in the face of climate change based on two factors, namely environmental and cognitive. This study uses a quantitative approach obtained through surveys with questionnaires and qualitative data research obtained through interviews with informants and field observations. The results showed that there was a relationship between environmental factors of farmers and farmers' cognitive factors, environmental factors with farmer's adaptive behavior, and cognitive factors with farmers' adaptive behavior in facing climate change
Keyword: Climate change, Farmers, Social Learning Theory

Judul: Tipologi Keluarga, Strategi Adaptasi Nafkah, dan Ketahanan Ekonomi Keluarga dalam Menghadapi Perubahan Iklim pada Keluarga Petani
Abstrak: Perubahan iklim memiliki dampak begitu besar dalam kehidupan, khususnya keluarga petani yang menggantungkan sumber kehidupannya pada iklim dan cuaca. Tipologi keluarga memiliki peran penting sebagai basis dalam melakukan strategi adaptasi nafkah untuk mencapai ketahanan ekonominya. Tujuan penelitian ini adalah menganalisis pengaruh antara karakteristik keluarga, tipologi keluarga, strategi adaptasi nafkah, dan ketahanan ekonomi keluarga. Penelitian ini menggunakan pendekatan kuantitatif dengan teknik penarikan contoh purposive sampling terhadap 60 petani di Kota Bogor selama Januari-Februari 2024. Para petani dalam penelitian sebagian besar tipologi keluarganya masuk kategori tinggi, lebih dari setengahnya tergolong rendah dalam strategi adaptasi nafkah, dan setengahnya belum mencapai kategori tinggi pada ketahanan ekonomi keluarga sehingga masih perlu ditingkatkan. Hasil uji regresi menunjukan bahwa pendidikan suami, ketangguhan keluarga, dan pola nafkah ganda berpengaruh positif signifikan terhadap ketahanan ekonomi keluarga, Climate change has a huge impact on sustaining life, especially for farmer families who depend on climate and weather for their livelihood. Family typology has an important roles as a basis for carrying out livelihood adaptation strategies to achieve economics resilience. The purpose of this study is to analyze the influence between family characteristics, family typologies and livelihood adaptation strategies to family economic resilience. The method used was quantitative approach with purposive random sampling technique of 60 farmers in Bogor City during January-February 2024. Most of the farmers in this study have a high category in family typology, more than a half are in low category of livelihood adaptation strategy, and half are not achieve a high category of family economic resilience so they still need to be improved. The result of multiple lineal regression shows that husband education, family hardiness, and dual income strategy has a significant positive effect on family economic resilience.
Keyword: climate change, family economic resilience, family typology, farmer
families, family typology

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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