Judul: Pengembangan Sistem Pemasaran Produk Kosmetika dan Fragrance Hasil Perbandingan Cara Konvensial dan Multi Level Marketing
Abstrak: Peningkatan taraf hidup inasyarakat Indonesia mendorong perkembangan peinasaran produk kosmetika dan fragrance yang cukup pesat. Departemen Perindustrian (1992) memperkirakan peningkatan permintaan produk kosmetika danfragrance rata-rata 27.38 persen pertahun. Perkembangan situasi yang menguntungkan ini diantisipasi oleh berbagai perusahaan hingga akhirnya menimbulkan persaingan yang selnakin tajam. Di Indonesia dikenal dua macam sistem pemasaran produk kosmetika dan fragrance, yaitu secara konvensional dan nzulti level marketing. Sistem konvensional adalah sistem pemasaran yang menggunakan pedagang perantara seperti distributor, pedagang besar, dan pengecer (Kotler, 1991). Multilevel marketing didefinisikan sebagai sistem pemasaran yang lnengandalkan teknik penjualan secara langsung (direct selling) kepada konsumen (Gattoma, 1990). Penelitian ini bertujuan untuk mengkaji situasi pemasaran produk kosmetika danfragrance di Indonesia, mengkaji sistem pemasaran produk kosmetika danfragrance secara konvensional di PT Teguh Pesona, dan multi level marketing di PT Nice Indo Pesona, membuat perbandingan antara kedua sistem pemasaran dan memberikan usulan sistem alternatif hasil pengembangannya, serta membuat sistem komputerisasi jaringan distribusi untuk sistem altematif yang diusulkan.
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Judul: Formulasi Strategi Pernasaran Produk Kosmetika Tradisional Melalui Analisis Faktor Internal dan Eksternal Perusahaan
Abstrak: Indonesia merupakan salah satu negara yang memiliki potensi agroindustri yang cukup besar. Salah satu produk agroindustri yang dapat meningkatkan nilai tambah hasil pertanian adalah produk kosmetika. Menurut Badan Pusat Statistik permintaan akan produk-produk kosmetika mencapai lebih dari 70.000 unit selama tahun 1999 (BPS, 1999). Besarnya permintaan akan produk kosmetika merupakan daya tarik industri ini, sehingga menjadi semakin berkembang.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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