Judul: Antidiabetic activity and analysis of phytochemistry aqueous and ethanol extract of purple leaf (Graptophyllum pictum (L.) Griff)
Abstrak: Daun wungu (Graptophyllum pictum (L.) Griff) merupakan salah satu tanaman dari famili Acanthaceae. Tanaman lain yang berada dalam satu famili dilaporkan memiliki aktivitas antidiabetes melalui mekanisme inhibisi enzim α- glukosidase, sehingga diduga daun wungu juga memiliki aktivitas antidiabetes tersebut dan diamati kandungan fitokimianya. Aktivitas antidiabetes daun wungu dilakukan dengan menentukan besarnya daya hambat ekstrak daun wungu terhadap enzim α-glukosidase, intensitas warna yang dihasilkan dibaca serapannya pada panjang gelombang 400 nm dengan microplate reader dan dihitung persentase daya hambat ekstrak daun wungu terhadap enzim α- glukosidase. Maserasi daun wungu dilakukan dengan menggunakan empat jenis pelarut, yaitu etanol 96, 70, dan 30% serta air. Hasil yang diperoleh menunjukkan nilai inhibisi α-glukosidase oleh ekstrak etanol 96, 70, 30 dan air berturut-turut 61.09%, 66.11%, 58.55% dan 40.13%. Analisis fitokimia menunjukkan bahwa ekstrak dengan pelarut etanol 96% dapat mengekstraksi senyawa alkaloid, flavonoid, tanin dan steroid; pelarut etanol 70% mengekstraksi alkaloid, flavonoid, tanin, saponin dan steroid; pelarut etanol 30% mengekstraksi alkaloid, flavonoid dan saponin; dan pelarut air mengekstraksi alkaloid dan flavonoid. Ekstrak etanol 96% dan 70% merupakan dua ekstrak dengan persentase inhibisi α- glukosidase diatas 50%, yaitu sebesar 61.09% dan 66.11% sehingga dapat dikatakan bahwa kedua ekstrak tersebut berpotensi sebagai antidiabetes. Pelarut yang dapat mengekstraksi seluruh senyawa yang diharapkan adalah etanol 70%.
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Judul: Aktivitas Inhibisi Enzim α-Glukosidase dan Antioksidan dari Ekstrak Etanol Daun Wungu (Graptophyllum pictum (L.) Griff) dan Partisinya
Abstrak: Wungu leaves (Graptophyllum pictum (L.) Griff) is a plant that is widely used in treating a variety of ailments, including diabetes and known to contain phenolic compounds that have antioxidant activity. The purpose of this study was to determine the inhibition of the enzyme α-glucosidase and antioxidant activities of ethanol extracts and fractions of diethyl ether, ethyl acetate, and butanol from wungu leaves (Graptophyllum pictum (L.) Griff) by in vitro studies. Extraction of wungu leaves was done by maceration and the fractination was done through liquid-liquid extraction. Results showed that ethanol extracts and its fraction have no inhibitory activity toward α-glucosidase, but it was potentially as antioxidant through inhibition of radical DPPH. Ethyl acetate fraction (500 ppm) can capture the DPPH radical 74.105% with IC50 values of 68.11 ppm which is the highest antioxidant activity and is followed by the fraction of butanol, ethanol, and diethyl ether.
Keyword: DPPH, wungu leaves, α-glucosidase, antioxidant, antidiabetic

Judul: Pengaruh Pairing pada Isotop Sn dengan Menggunakan Pemodelan Sembilan Tingkat Energi
Abstrak: Formation of the neutron-rich tin isotopes (Sn isotopes) is the one of the interesting topics in the field of nuclear reaction, especially regarding the stability of the heavy nuclei. Calculations of total energy using the BCS approach using five energy levels can only calculate the total energy up to Sn50132. On the other hand, the experiment continues and has exceeded the formation of isotopes. Therefore, there is need for a new model to accomadate more neutrons. In this research, Sn isotopes is modelled using nine energy levels and constant interaction potential to explain the pairing phenomenon up to Sn50154. However, to obtain more accurate results, other methods to minimize the differences with the experimental results are clearly needed here.
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