Judul: Analisis Guild Burung di Beberapa Tipe Habitat di Hutan Lambusango, Pulau Buton, Sulawesi Tenggara
Abstrak: The existence of a guild can be used as the indicator of habitat change. The objective of this research is to identify guild composition and analyze factors that influence guild diversity in primary forest, secondary forest, and mix plantation. This research was conducted on July, 4th-31st in primary forest, secondary forest, and mix plantation in Lambusango forest. The result shows that secondary forest holds the highest guild composition although there was no big difference in the number of guild among the three habitat types. Insectivores always dominate guild composition in every habitat types. It might be influenced by the stability and availability of the insect population throughout the year. Frugivore is the next dominance guild in every habitat type. Middle and upper canopy are the dominant substrate used by insectivore and frugivore. Sally is the dominant behavior type that frequently used by insectivore while glean and reach is the dominant behavior that frequently used by frugivore.
Keyword: Lambusango forest, habitat, Guild

Judul: Komunitas Burung pada Beberapa Habitat dengan Gangguan Berbeda di Hutan Lambusango, Pulau Buton, Sulawesi Tenggara
Abstrak: Habitat changes due to past disturbances may affect bird communities in Lambusango forest. This research is aimed at examining bird diversity, and comparing bird composition in several habitats with different disturbance levels. The study shows an increasing number of species, population and diversity index (H') from habitats with low to high disturbance level. Birds in primary and secondary forests have the similarity level of 77%. The composition of specialist birds differs from one habitat to another. Primary forest becomes the habitat of two types of interior birds that can be used as an indicator for undisturbance habitats, those are White-bellied Imperial Pigeon (Ducula forsteni) and Sulawesi Dwarf Kingfisher (Ceyx fallax).
Keyword: lambusango forest, habitat disturbance, bird communities

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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