Judul: Designing a Custom Coffee Order Website Business Model in Bogor City
Abstrak: Biji kopi merupakan bahan baku utama bagi kedai kopi yang sangat mempengaruhi kualitas dan variasi cita rasa minuman kopi. Mayoritas kedai kopi melewati proses panjang dalam mencari bahan baku mulai dari keterbatasan informasi, ketidakpastian kualitas, ketidakkonsistenan cita rasa, dan lokasi jauh. Penelitian ini bertujuan menganalisis permasalahan dan menemukan solusi yang dihadapi para kedai kopi, merancang prototipe, dan model bisnis “Explorer Coffee” online store penyedia biji kopi berbasis website dengan pendekatan design thinking. Online store “Explorer Coffee” yang melayani kustomisasi pembelian kopi dapat menjadi solusi dari permasalahan kedai kopi. Menawarkan seluruh kebutuhan kopi dengan berbagai layanan kustomisasi kopi mulai dari biji hiaju kopi (greenbearn), sangrai kopi (roasting), biji kopi sangrai (roasted been), dan biji kopi sangrai berdasarkan cita rasa yang dicari. Solusi ini dapat diakses mudah melalui website mobile friendly yang dapat diaskse dari mana saja kapan saja., Coffee beans are the primary raw material for coffee shops, greatly influencing the quality and flavor variety of coffee drinks. Most coffee shops undergo a lengthy process in sourcing raw materials, starting from limited information, quality uncertainty, flavor inconsistency, to distant locations. This research aims to analyze the problems faced by coffee shops, find solutions, design prototypes, and establish the business model of "Explorer Coffee," an online store providing coffee beans based on a website with a design thinking approach. The "Explorer Coffee" online store, which offers customized coffee purchases, can serve as a solution to coffee shop issues. It provides all coffee needs with various customization services including green bean, roasting, roasted bean, and roasted bean based on desired flavor profiles. This solution is easily accessible through a mobile-friendly website that can be accessed from anywhere at any time.
Keyword: Coffee Beans, Websit, online store, Kedai Kopi, Biji kopi, Online Store, website, Supplier, Design thinking, Supplier, Design thinking, Coffee Shop

Judul: Pengembangan Model Bisnis Kedai Kopi Lima Sore
Abstrak: Konsumsi kopi di Indonesia mengalami peningkatan sehingga muncul banyak kedai kopi di Indonesia, khususnya di Kota Bogor dalam beberapa tahun terakhir yang salah satunya adalah Kedai Kopi Lima Sore. Penelitian ini bertujuan untuk 1) mengetahui Business Model Canvas (BMC) awal, 2) mengidentifikasi strategi bisnis yang diterapkan dan 3) merancang perbaikan BMC dari Kedai Kopi Lima Sore. Pengambilan data dilakukan sejak Maret hingga Juli 2019 yang kemudian dianalisis dengan menggunakan BMC. Hasil penelitian ini, pertama, BMC awal dipetakan dalam sembilan elemen sesuai dengan hipotesis pendiri. Kedua, strategi bisnis yang dilakukan adalah strategi pemasaran harga, produk dan promosi. Ketiga, perbaikan BMC dalam sembilan elemen menekankan pentingnya customer segments dan value propositions sehingga Kedai Kopi Lima Sore mampu menawarkan produk yang sesuai dengan kebutuhan pelanggannya. Berdasarkan strategi bisnis, Kedai Kopi Lima Sore disarankan lebih mengutamakan strategi promosi pada tahap awal mengembangkan usahanya.
Keyword: Business Model Canvas, kopi, strategi pemasaran

Judul: Virological and Immunological Studies of Dengue Virus Infection in Pigtail Macaques (Macaca nemestrina).
Abstrak: Dengue virus infections have caused a major public health problem in tropical and sub-tropical countries. The geographical distribution, the frequency of epidemic cycle and the number of cases have been increasing at an alarming rate and highlighted the urgency of DEN vaccine (WHO 2005; Raviprakash et al. 2009). The clinical manifestations of DEN infections range from mild dengue fever (DF) with high fever, headache, rash, and bone and muscle pain up to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with evidence of thrombocytopenia, bleeding, plasma leakage and shock. The severe manifestation cause a high mortality rate particularly in children (WHO 2005). Since the 1980s, epidemiological data revealed that 85% of DHF and DSS were heterologous secondary infections and immunopathological response to heterologous secondary infection has been hyphothesized leading to DHF pathogenesis (Halstead 1983). Antibody produced following primay DEN infection confers the protection to homologous infection, however, heterologous secondary infection may still occur. The pre-existing, non-neutralizing antibodies binds DEN viruses and these complexes, then bind the target cells via the FcγRI and FcγII, resulting in increased viral load, shortened incubation period and increased disease severity (Fink et al. 2006). Meanwhile, DEN specific CD4+ and CD8+ T lymphocytes are suggested to have a low binding affinity for the current serotype, and consequently, inefficient to clear the infection (Fink et al. 2006). The limitations of DEN study in human have hampered the understanding of these two components of adaptive immunity, antibody and T lymphocyte, in the pathogenesis of DHF.
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