Judul: Aktivitas Ekstrak Daun Pelawan Dalam Memperbaiki Kinerja Ovarium Dan Involusi Uterus Pascamelahirkan
Abstrak: Pelawan leaf extract from Myrtaceae family contains bioactive compounds such as flavonoids, alkaloid, tannin, phenol, and steroid. The objective of the study was to analyze antioxidant activity from ethanol extract and extract fraction of Pelawan leaf. Antioxidant activity was measured using DPPH (2,2-diphenyl-1-picryl-hydrazylhydrate) radical photometric assays in a process guided by the discoloration. Pelawan (Tristaniopsis obovata Benn.) leaf simplicial was macerated with 70% ethanol to obtain ethanol extract, then were partitioned with n-Hexane, ethyl acetone, and water solvents to obtain the fraction of hexane, ethyl acetate, and water extracts. Antioxidant activity of ethanol and fraction of Pelawan extract were analyzed using DPPH method. The results showed that IC50 value of ethanolic Pelawan extract was lower than the other three extract fractions. Among the partitions, ethyl acetate and water fractions had higher antioxidant activity (AA) than hexane fraction. This study showed that ethanol, ethyl acetate, and water fraction extracts have high antioxidant activities as a potential nutrient and treatment material., Pelawan leaves contain steroids that can affect the female reproductive system. The aim of this study was to examine the effectivity of Pelawan ethyl acetate fraction extract on ovarian physiology of postpartum rat, based on the prediction of the litter size, birth weight, estrogen levels, and ovarian weight. The treatment was divided into the group of maternal rats giving birth once and giving birth twice. Each treatment consisted of control without Pelawan extract, maternal rats administered orally with Pelawan extract at doses of 50 mg/kg BW, 100 mg/kg BW, and 150 mg/kg BW. The results showed that the litter size and birth weight of baby rats born to maternal rats giving birth twice increased in the maternal rats treated with ethyl acetate fraction at a dose of 50 mg. The litter size and birth weight of baby rats born to maternal rats giving birth once decreased on maternal rats treated with ethyl acetate fraction at a dose of 100 mg. The estrogen concentration levels in all treatments decreased on day 3 and increased on day 5. The estrogen concentration levels in maternal rats treated with ethyl acetate fraction at a dose of 100 mg were higher than those in maternal rats treated at doses of 50 mg and 150 mg. The ovarian weight decreased on day 3 and increased on day 5. The ovarian weight of rats giving birth twice treated at a dose of 100 mg increased compared to the other doses. Pelawan extract has bioactive compounds that affect the litter size, birth weight, estrogen levels, and ovarian weight. Allegedly, the antioxidant compounds in the extract affect the performance of growth hormone and growth factors to produce LH and FSH in the pituitary, Ethyl acetate fraction of Pelawan extract has been tested to have steroid content and high antioxidant activity which can be used for treatment. The study examined the effect of ethyl acetate fraction of Pelawan extract in physiological repairing of postpartum rat uterus based on the activities of SOD, MDA, the expression of ER α, and Cu, Zn SOD. The treatment was divided into the group of maternal rats giving
Keyword: antioxidant activity, DPPH, Myrtaceae, Tristaniopsis obovata

Judul: Antioxidant Activity of Pelawan (Tristaniopsis merguensis Griff.) Heartwood Extract
Abstrak: Penelitian ini bertujuan menentukan kadar ekstraktif dan aktivitas antioksidan fraksi hasil fraksinasi ekstrak aseton kayu teras pelawan (Tristaniopsis merguensis) serta analisis kimia fraksi terbaik berdasarkan antioksidannya. Pengujian aktivitas antioksidan dilakukan secara in vitro dengan metode DPPH. Analisis kimia menggunakan Py-GC-MS. Hasil penelitian menunjukkan kadar ekstrak aseton 1,99% yang terdiri dari fraksi n-heksan (FN), etil eter (FEE), etil asetat (FEA), dan residu (FR) dengan kadar ekstrak berturut-turut 0,21%; 0,49%; 0,17%; dan 1,12%. Aktivitas antioksidan FR relatif sama dengan FEA dan lebih tinggi dari FEE dan FN karena persentase inhibisi FR, FEA, FEE, dan FN pada konsentrasi ekstrak 50 ppm yaitu 86,15%; 84,59%; 59,54%; dan 8,87%. Hasil analisis Py-GC-MS menunjukkan FR dan FEA mengandung 9 dan 40 senyawa dengan konsentrasi relatif (KR) tertinggi 2-Cyclopenten-1-one pada FR (43,02%) dan dioctyl phthalate pada FEA (17,8%). Senyawa yang berdasarkan penelusuran pustaka memiliki aktivitas antioksidan adalah phenol, guaiacol, 2,6-dimethoxhyphenol dan 1,4-di-tert-butoxybenzene dengan KR berturut-turut 2,79%, 5,46%, 5,84% dan 25,72% di dalam FR dan guaiacol, 2,6-dimethoxyphenol, acetovanillone dan bis(2-ethylhexyl) adipate dengan KR berturut-turut 3,61%, 7,17%, 3,57% dan 2,34% di dalam FEA., This research aims to determine the extract content, the antioxidant activity of fractions from fractionation of the acetone extract of pelawan (Tristaniopsis merguensis) heartwood, and analyze the chemical compounds from the most active fraction based on its antioxidant activity. Antioxidant activity was tested using in vitro DPPH method. The chemical analysis was done using Py-GC-MS. The result showed that the extract content of pelawan heartwood has 1,99%, consist of nhexane (FN), ethyl ether (FEE), ethyl acetate (FEA), and residue fraction (FR) with extract contents of 0,21%; 0, 49%; 0,17%; and 1,12%. Antioxidant activity of FR is relatively the same with FEA, and was higher than FEE and FN with their %inhibition at 50 ppm concentration were 86,15%; 84,59%; 59,54%; and 8,87%. Py-GC-MS showed that FR and FEA have 9 and 40 compounds which the highest relative concentration (KR) are 2-cyclopenten-1-one in FR (43,02%) and dioctyl phthalate in FEA (17,8%). Based on literature, compounds that has antioxidant activity are phenol, guaiacol, 2,6-dimethoxhyphenol and 1,4-di-tertbutoxybenzene with KR of 2,79%, 5,46%, 5,84% and 25,72% in FR and guaiacol, 2,6-dimethoxyphenol, acetovanillone and bis(2-ethylhexyl) adipate with KR of 3,61%, 7,17%, 3,57% and 2,34% in FEA
Keyword: acetone extract, antioxidant, fractionation, Tristaniopsis merguensis

Judul: Closed Knight’s Tour pada Papan Catur Berbentuk Persegi Panjang dengan Ukuran Maksimal 8 × 8
Abstrak: Closed Knight’s Tour merupakan langkah kuda yang mengunjungi setiap kotak pada papan catur tepat satu kali dengan langkah kuda berawal dan berakhir pada kotak yang sama. Graf yang terbentuk dari closed knight’s tour dinotasikan sebagai graf G(m,n), dengan m adalah banyaknya baris dan n adalah banyaknya kolom. Graf tersebut memuat Hamiltonian cycle. Sebuah graf terhubung G adalah graf bipartite jika dan hanya jika graf tersebut tidak memiliki cycle dengan panjang ganjil. Papan catur yang memenuhi syarat cukup untuk memiliki closed knight’s tour adalah papan catur berukuran 5 × 6, 5 × 8, 6 × 6, 6 × 7, 6 × 8, 7 × 8, dan 8 × 8.
Keyword: bipartite, closed knight’s tour, hamiltonian cycle, knight’s tour, teori graf