Judul: Analisis Risiko Kejadian Demam Berdarah Dengue Berdasarkan Informasi ENSO dan IOD (Studi Kasus Pulau Jawa)
Abstrak: Dengue fever disease (DBD) is an infectious and endemic disease that is increase doing in the beginning and ending of rainy season. The disease is caused by the Dengue virus that related with influence of climate variability, including rainfall. Rainfall is affected by El Nino Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) phenomenon. ENSO and IOD information will provide benefits in the determination of the dengue incidence rate, especially in the area which has monsoon rainfall type, like Java Island. However, not all areas in Java Island are affected by ENSO and IOD phenomenon. The objective of this study is to determine the influence of ENSO and IOD phenomenon with respect to dengue incidence rate in the form of a DBD area vulnerability map. The analysis is use correlation between ENSO and IOD against developed incident rate (IR) of DBD in Java. Then, the vulnerability areas using GIS (geographic information system). This study demonstrated that when ENSO and IOD was in the Positive 4 phase, most areas in Java are hyperendemic. After that, we predicted IR DJF with IOD and ENSO. The correlation between IR December-January-February (DJF) and IOD is 0.480 in cluster fourth of June. The correlation between March’s ENSO and IR DJF is 0,586 in cluster sixth. The prediction of IR March-April-May (MAM) is only affected by the correlation of November’s IOD 0,662 on cluster Sixth. Commonly, ENSO and IR haven’t a significant correlation and effect toward DBD cases in some parts of Java Island.
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Judul: Appropriateness of the Onset Period of Dengue Fever with the Onset of Rainy Season and Determining the Level of Case Vulnerability in Central Java
Abstrak: Demam Dengue (DD) merupakan penyakit yang sering terjadi di Indonesia. Salah satu faktor iklim yang berpengaruh terhadap penyakit DD adalah curah hujan. Setiap daerah memiliki tingkat kerawanan kasus yang berbeda-beda, sehingga perlu penentuan tingkat kerawanan untuk menentukan prioritas penanggulangannya. Penelitian ini bertujuan (a) mengetahui kesesuaian periode onset kejadian DD dengan periode onset musim hujan (MH), serta (b) mengetahui tingkat kerawanan kasus DD di Provinsi Jawa Tengah. Periode onset MH ditentukan berdasarkan anomali kumulatif dan kriteria berjenjang BMKG. Periode onset kejadian DD juga ditentukan berdasarkan anomali kumulatif dimana nilai minimum diidentifikasi sebagai periode onset. Tingkat kerawanan ditentukan berdasarkan tingkat peluang dari nilai indeks kerawanan. Hasil menunjukkan bahwa penentuan periode onset MH berdasarkan metode kriteria berjenjang BMKG memberikan persentase kesesuaian lebih tinggi dengan onset kejadian DD yaitu sebesar 62% dibandingkan dengan metode anomali kumulatif dengan persentase sebesar 53%. Periode onset kejadian DD yang terjadi bersamaan dengan onset MH kebanyakan terjadi di bulan Desember. Tingkat kerawanan kasus DD berada pada kategori agak aman (2 kabupaten), agak rawan (1 kabupaten), rawan (3 kabupaten), sangat rawan (23 kabupaten/kota), hingga amat sangat rawan (6 kabupaten/kota)., Dengue Fever (DF) is a disease that often occurs in Indonesia. One of the climatic factors that affect DF disease is rainfall. Each region has a different level of case vulnerability, so it is necessary to determine the level of vulnerability to choose the priority of countermeasures. This research aims to (a) determine appropriateness of the onset period of dengue fever with the onset of rainy season (RS), and (b) determine the level of vulnerability for DF cases in Central Java Province. The onset period of RS is determined based on the cumulative anomalies and tiered criteria of BMKG. The onset period of DF events is also determined based on cumulative anomalies, which is the minimum value is identified as the onset period. The level of vulnerability is determined based on the probability level of vulnerability index. The results show that determining the onset period of RS based on tiered criteria of BMKG provides a higher percentage of appropriateness with the onset of DF events, namely 62% compared to the cumulative anomalies method with a percentage of 53%. The onset period of DF events which occurred simultaneously with the onset of RS mostly occurred in December. The level of vulnerability for DF cases is in the category of slightly safe (2 districts), slightly vulnerable (1 district), vulnerable (3 districts), very vulnerable (23 districts/cities), and extremely vulnerable (6 districts/cities).
Keyword: curah hujan, Faktor Meteorologi, demam dengue, kerawanan, periode onset

Judul: Sintesis 1-Kloro-2-metoksi-6-propilnaftalena-1,3-dioksolana (1:1) sebagai Prekursor Asam (S)-(+)-(6-Metoksi-2-naftil)propanoat
Abstrak: Senyawa 1-kloro-2-metoksi-6-propilnaftalena-1,3-dioksolana (1:1) sebagai prekursor asam (S)-(+)-(6-metoksi-2-naftil)propanoat disintesis dari bahan awal 2-metoksinaftalena. Tahapan sintesis diawali dengan klorinasi menggunakan 2 jenis pereaksi klorinasi, yakni isosianurat terklorinasi dan NaOCl. Klorinasi dengan isosianurat terklorinasi berhasil menyintesis 1-kloro-2-metoksinaftalena sebagai produk monoklorinasi melalui pencirian dengan kromatograf gas-spektrometer massa (GC-MS). Nisbah konversi produk paling efisien diperoleh pada laju penambahan 2.5 mmol/jam. Sebaliknya, klorinasi dengan NaOCl menghasilkan produk triklorinasi. 1-Kloro-2-metoksinaftalena selanjutnya diasilasi dengan propanoil klorida, tetapi analisis dengan GC menunjukkan bahwa produk asilasi tidak terbentuk. Sistem bebas-air diperlukan untuk keberhasilan proses asilasi tersebut.
Keyword: isosianurat terklorinasi, NaOCl, nisbah konversi