Judul: Analisis Daya Dukung Lingkungan Kota Bandar Lampung.
Abstrak: Kota Bandar Lampung merupakan salah satu kota yang memiliki laju pertumbuhan penduduk yang tinggi pada tahun 2010-2019 yaitu 1.73% dalam sepuluh tahun. Pemanfaatan lahan maupun air yang tidak sesuai pada akhirnya akan menurunkan daya dukung lingkungan. Daya dukung lingkungan penting untuk diketahui dan dijadikan dasar dalam perencanaan pemanfaatan sumber daya alam, perencanaan pembangunan dan perencanaan pemanfaatan ruang. Penelitian ini bertujuan untuk menganalisis daya dukung lingkungan di Kota Bandar Lampung dengan menentukan status daya dukung lingkungan. Analisis dilakukan berdasarkan peraturan yang berlaku mengenai analisis daya dukung lingkungan. Penelitian ini menggunakan data sekunder yang mencakup data spasial dan data non spasial. Hasil analisis menunjukkan ketersediaan dan kebutuhan air di Kota Bandar Lampung berstatus defisit atau terlampaui pada tahun 2019 dan tahun 2030. Daya dukung lingkungan Kota Bandar Lampung berdasarkanketersediaan dan kebutuhan lahan juga berstatus defisit pada tahun 2019 dan tahun 2030.
Keyword: air, defisit, kemampuan lahan, lahan, penduduk

Judul: Analisis perubahan ruang terbuka hijau dan strategi pengembangannya di Kota Bandar Lampung:
Abstrak: Development of Bandar Lampung City has the great influenced to the land use changes. Land use conversion commonly happen on Green Open Space (GOS) into other usages. The aims of this research are : (a) to identify GOS change in Bandar Lampung City along the year 2000-2007; (b) to identify GOS needed base on regulation of spatial planning (UU No 26/2007) and number of population; (c) to identify center of GOS change into built up area related to the regional development and the factors that affected the change; (d) to identify divergency of GOS change in RTRW (Public Document of Regional Planning); and (5) to find the strategy to maintain and develop GOS. This research was conducted by Landsat analysis using Geographic Information System (GIS) and combined with Location Quotient Analisys (LQ) to analize GS change. Scalogram and regression analysis used for analize the regional development and the factors that affected the GOS change. The result showed that forest, mixed dry farming, plantation and paddy field decrease of 1.449 Ha (7.35%) in 7 years, since year 2000 to 2007. Meanwhile, built up area increase to 1.218 Ha (6,19%). Based on UU No 26/2007, availability of GOS in Bandar Lampung City are still sufficient (> 30%), it’s about 61.40% (12.110 Ha) from the total area of the city. Analysis of GOS needed based on area found that in subdistrict level at Tanjung Karang Pusat and Kedaton subdistrict insufficient GOS. Based on standard for number of population, Tanjung Karang Pusat, Kedaton and Teluk Betung Selatan subdistrict still in below standard. The changes center of GOS in Bandar Lampung City happen in 63 villages, which are distributed in hierarchy III 79,57 % villages, hierarchy II 16,60% village, and hierarchy I 3,83% village. There are 2 factors that affected GOS change, one is village development index and another is number of population. Land use change from GOS and protection area into built up area was found as deviation of RTRW. The strategy to maintain and to develop GOS depend on the availability and the problem that occur with GOS, so GOS can be developed optimally.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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