Judul: Analisis Resiliensi Ekologis Berdasarkan Perubahan Garis Pantai di Kabupaten Tangerang
Abstrak: Wilayah pesisir Kabupaten Tangerang mengalami perubahan garis pantai secara terus-menerus yang disebabkan oleh faktor alam maupun aktivitas manusia. Perubahan yang terus terjadi ini dapat mempengaruhi tingkat resiliensi ekologi yang ada di pesisir. Tujuan dari penelitian ini adalah menilai tingkat resiliensi ekologi berdasarkan dinamika perubahan garis pantai, serta kaitannya dengan penggunaan dan tutupan lahan di pesisir Kabupaten Tangerang. Analisis data terdiri atas pengolahan citra satelit Landsat, analisis penggunaan dan tutupan lahan (land use land cover/LULC), laju perubahan garis pantai menggunakan Digital Shoreline Analysis System (DSAS), pengolahan data oseanografi, dan penilaian resiliensi. Hasil penelitian menunjukkan bahwa pesisir Kabupaten Tangerang memiliki tingkat resiliensi rendah dengan dinamika perubahan garis pantai lebih dominan erosi daripada akresi. Kawasan yang mengalami erosi tinggi cenderung tidak resilien dengan LULC dominan adalah lahan tambak dan sedikit mangrove, sedangkan kawasan yang mengalami akresi tinggi memiliki tingkat resiliensi tinggi dengan LULC muara sungai., The coastal area of Tangerang Regency experiences continuous changes in the coastline caused by natural factors and human activities. These ongoing changes can affect the level of resilience on the coast. The purpose of this study was to assess the level of resilience based on the dynamics of shoreline change, as well as its relation to land use and land cover on the coast of Tangerang Regency. Data analysis consisted of processing Landsat satellite imagery, land use and land cover (LULC) analysis, shoreline change rate using Digital Shoreline Analysis System (DSAS), oceanographic data processing, and resilience assessment. The results showed that the coast of Tangerang Regency has a low level of resilience with the dynamics of shoreline change being more dominant in erosion than accretion. Areas that experience high erosion tend to be less resilient with dominant LULC being ponds and few mangroves, while areas experiencing high accretion have high resilience levels with LULC of river mouths.
Keyword: change of shoreline, coastal, LULC, resilience

Judul: Analisis Perubahan Garis Pantai dengan Menggunakan Citra Satelit Landsat di Pesisir Kabupaten Tangerang, Banten.
Abstrak: Garis pantai dapat berubah secara terus menerus yang disebabkan oleh proses alami maupun aktivitas manusia. Teknologi penginderaan jauh dapat digunakan untuk melakukan pengamatan perubahan garis pantai. Tujuan penelitian ini adalah mengetahui jarak perubahan garis pantai pada tahun 1995-2015 dengan menggunakan citra satelit Landsat serta mengidentifikasi faktor yang mempengaruhinya di pesisir Kabupaten Tangerang, Banten. Ekstraksi garis pantai menggunakan metode single band, band ratio, dan RGB composite. Perhitungan jarak perubahan menggunakan perangkat lunak Digital Shoreline Analysis System (DSAS). Hasil analisis jarak perubahan garis pantai menunjukkan abrasi sebesar 15.9-44.5 m/thn dan akresi sebesar 21.9-101.1 m/thn. Abrasi tertinggi terjadi di Kecamatan Mauk, sedangkan akresi tertinggi terjadi di Kecamatan Teluknaga. Perubahan garis pantai yang terjadi dapat disebabkan dari hantaman gelombang, arus susur pantai (longshore current), adanya alih fungsi lahan mangrove menjadi lahan tambak, dan masukan sedimen dari sungai-sungai di sekitarnya.
Keyword: abrasi, akresi, DSAS, garis pantai, penginderaan jauh

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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