Judul: Kajian Morfologi Proses Persembuhan Kerusakan Segmental Pada Tulang Domba Yang Diimplan Dengan Komposit Hidroksiapatit-Trikalsium Fosfat (HA-TKF)
Abstrak: This study was aimed to evaluate in vivo osteogenesis potency of bones implanted with graft of hydroxyapatite-tricalcium phosphate (HA-TCP) composite. This study also observed the potential use of HA-TCP as bone substitution material. Three local sheeps were used in this study. The implant was inserted under aseptic surgery on the proximal medial of the left tibia bone and as control the proximal medial of the right tibia bone was drilled without implant. Bones were harvested after 30, 60, and 90 days post-surgery and observed macroscopic and microscopically. The parameters of observation were the condition, shape and degradation degree of the implant, bonding between implant and host bone, new bone growth into the implant and signs of inflammation reaction around the implant. The result showed that the healing process on control bone was faster than those of the implanted bone. The bone implant had been already degradated in treated group of day 30 post-surgery. HA-TCP bone implant shown some signs for its biocompatibility, biodegradability, bioresorbability and osteoconductivity properties. Therefore, it is suggested that HA-TCP implant might be used as bone substitution in the bone lesions with approximately 30 days of recovery.
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Judul: Kajian Morfologi Proses Persembuhan Kerusakan Segmental Pada Tulang Domba Yang Diimplan Dengan Komposit Hidroksiapatit-Kitosan (HA-K)
Abstrak: This research was aimed to study the morphology of healing process on sheep’s bone implanted with hydroxyapatite-chitosan (HA-C) composite. This research would also present information about the potency of HA-C composite as synthetic bone graft biomaterial or bone implant. Three local sheeps were used in this study. HA-C composite was implanted on the medial of the left tibia bone while the same part of right tibia was treated as control without implant. All implant were harvested at 30, 60, and 90 days post-operation. The observation parameters were the condition, shape, and degradation degree of the implant, bonding between implant and host bone, new bone ingrowth into the implant, and signs of inflammation reaction around the implant. The result showed that the healing process on control bone was faster than those of the implanted bone. As far as 90 days observation in this present study was concerned, HA-C implant did not show characteristics for biodegradability, bioresorbability, osteoconductivity, and bioactivity. However, it showed biocompatibility properties for host body. It is suggested that the implant used in this study is more suitable to be developed as synthetic bone graft biomaterial for application on large defects with healing time longer than 90 days.
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Judul: Karakteristik massa air arlindo di Perairan Timur Indonesia pada musim timur
Abstrak: Sirkulasi massa air di perairan timur Indonesia yang dikenal secara internasional dengan istilah Indonesian Throughflow (Bray et al., 1996) atau Arus Lintas Indonesia (Arlindo) dalam Bahasa Indonesia (Ilahude dan Gordon, 1996) sangat menarik untuk diteliti. Penelitian ini bertujuan untuk menganalisis massa air Arlindo di perairan timur Indonesia pada musim timur, yang meliputi analisis jalur lintasan Arlindo dan karakteristik massa air yang terlibat di dalamnya. Karakteristik massa air di Samudera Hindia dan di wilayah ekuator bagian barat Samudera Pasifik dianalisis juga sebagai bahan perbandingan. Kegiatan penelitian adalah berupa pengolahan data sekunder yang diperoleh dari the National Oceanographic Data Center (NODC), NOAA, Amerika Serikat. Lintasan Arlindo dianalisis berdasarkan gambar kontur sebaran anomali kedalaman dinamik di lapisan permukaan 0 dbar relatif terhadap permukaan 1000 dbar. Karakteristik massa air dianalisis berdasarkan ciri-ciri core layer (King, 1963) yang terlihat dalam grafik suhu-salinitas (S-S) dan grafik suhu-oksigen (S-O₂). Sebaran nilai anomali kedalaman dinamik di lapisan permukaan 0 dbar relatif terhadap permukaan 1000 dbar menunjukkan nilai yang cukup tinggi di Laut Cina, Laut Sulu, Laut Sulawesi, dan sebagian Samudera Pasifik, yaitu antara 1,8 dyn m sampai 1,9 dyn m. Di sebelah timur Mindanao nilainya lebih kecil (1,5 dyn m sampai 1,7 dyn m), sedang di sebagian Laut Sulu nilainya lebih besar (2,0 dyn m sampai 2,1 dyn m).
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