Judul: Pengaruh Kuersetin terhadap Derajat Alergi dan Kadar Imunoglobulin E pada Marmot yang Diinduksi Putih Telur
Abstrak: Quercetin is one of flavonoid class which has been clinically proven for allergic and also has been syntheticed. It has not researched yet to determine the smallest which can effect as antiallergic. The guinea pigs divided into two groups, control (K) and Quercetin (Q) groups. Each groups were comprised three guinea pigs and all of it were adapted for 14 days. Guinea pigs were sensitized for 39 days with egg white 2 mg/mL dissolved by Al(OH)3 as adjuvant and buffer saline by forced egg white down. While, another three guinea pigs were adapted for 3 days to determine pharmacologic dosage based Lethal Dose 50 (LD50) of Quercetin. The result of this assay showed that at dose 13.92 mg/kg body weight is safe dosage. This dosage then used for determine the effect of quercetin as antiallergy with Evans blue dye as indicator (AKP method). The result of AKP showed that quercetin has no significant effect. The concentration of Immunoglobulin E (IgE) in guinea pigs serum also same for all guinea pigs < 2.4 ng/mL. The result of this research was quercetin at dose 13.92 mg/kg body weight has no significant effect as antiallergic.
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Judul: Pemberian Ovalbumin Sebagai Penyebab Alergi pada Marmot
Abstrak: Most people consider allergic is not dangerous. However in some cases may cause death. Allergic has been suspected to relate with immunoglobulin E (IgE) formation, followed by the release of histamine and other cells mediator, until the symptom occur. In this research, the effect of ovalbumin induction on allergic reaction was studied. The used guinea pigs were divided into control (K) and ovalbumin treatment groups, each containing three guinea pigs. Animals were adapted for 14 days then 40 days albumin induced for allergic reaction. Guinea pig’s blood were taken after 40 days sensitization and injected back (anafilaksis cutaneous pasif) to the animals. Evans blue were given after 48 hours serum injection, to obtain bluish spot formation for symptom observation. Research showed that ovalbumin induced allergic reaction. Anafilaksis cutaneous passive testing showed that the bluish diameter didn’t occure on guinea pig’s back, but the allergic effect occurred tend to systemic effect.
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Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
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