Judul: Profil Leukosit Sprague Dawley Pascaimplantasi Jangka Panjang Biomaterial Besi (Fe) Berpori pada Defek Os Femur.
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh implantasi jangka panjang biomaterial logam terdegrasi berbahan dasar besi berpori pada tulang femur terhadap gambaran leukosit tikus Sprague Dawley. Sebanyak 60 tikus Sprague Dawley dibagi dalam 4 kelompok. Masing-masing kelompok terdiri atas 15 ekor tikus dengan perlakuan kontrol, implan berpori 450 μm, 580 μm, 800 μm. Ukuran implan adalah panjang 5 mm, lebar 2 mm dan ketebalan 0,5 mm. Implantasi dilakukan pada permukaan os femur. Pengambilan sampel darah dilakukan selama sepuluh bulan pengamatan yaitu pada bulan ke- 2, 4, 6, 8 dan 10 pasca implantasi. Analisis data dilakukan menggunakan aplikasi software Statistical Product and Service Solutions (SPSS®) versi 16.0. Pengujian perbedaan profil darah putih antar kelompok dan waktu perlakuan dilakukan dengan uji one way ANOVA. Uji analisis duncan dilakukan jika hasil uji sebelumnya memiliki nilai P<0,05. Secara keseluruhan, profil leukosit, neutrofil batang, neutrofil segmen, basofil, eosinofil, limfosit dan monosit mengikuti pola fluktuasi yang sama dengan kontrol. Kesimpulan yang diperoleh adalah perlakuan implan besi berpori 450 μm, 580 μm, 800 μm tidak berpengaruh terhadap profil leukosit.
Keyword: implan, besi (Fe) berpori, persembuhan, leukosit

Judul: Profil Eritrosit Tikus Sprague Dawley Pasca Implantasi Biomaterial Besi (Fe) Berpori pada Os Femoris.
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh implantasi biomaterial besi berpori pada os femoris terhadap profil eritrosit tikus Sprague Dawley. Sebanyak 60 ekor tikus Sprague Dawley dibagi dalam 4 kelompok. Masing-masing kelompok terdiri dari 15 ekor tikus dengan perlakuan diameter pori implan 450 μm, 580 μm, 800 μm, dan kelompok kontrol yang tidak ditanamkan implan. Implan ditanamkan pada diafise os femoris. Pengambilan sampel darah dilakukan pada bulan ke-0, 2, 4, dan 6 pasca implantasi secara intra arterial melalui arteri coccygealis. Pemeriksaan profil eritrosit meliputi jumlah eritrosit, nilai hematokrit, kadar hemoglobin, dan indeks eritrosit (MCV, MCHC). Hasil penelitian dianalisis dengan uji one way ANOVA dan uji perbandingan ganda menggunakan program Statistic Program for Social Science (SPSS). Hasil penelitian menunjukkan jumlah eritrosit mengalami peningkatan pasca implantasi biomaterial Fe berpori, sehingga berpengaruh terhadap peningkatan nilai hematokrit dan kadar hemoglobin. Hal tersebut merupakan respon sumsum tulang terhadap perdarahan saat operasi. Hasil ini menunjukkan bahwa implantasi biomaterial Fe berpori tidak menyebabkan reaksi yang berlebihan pada eritrosit. Tidak adanya perbedaan yang nyata (p>0,05) pada nilai MCV dan MCHC menunjukkan bahwa implantasi biomaterial Fe berpori tidak memengaruhi profil eritrosit tikus Sprague Dawley, sehingga memiliki potensi untuk dijadikan alternatif biomaterial implantasi tulang.
Keyword: besi berpori (Fe), biomaterial, Os Femoris, profil eritrosit, tikus

Judul: Characteristic of Overshooting Top (OT) Based on  Himawari  8  Satellite  as  a  Convective  Cloud  Feature  that  Generates  Extreme Weather in the Java Island Region
Abstrak: Overshooting Top (OT) is a feature at the top of a convective cloud that is associated with extreme weather. Research on OT in tropical Indonesia is still very limited. The existence of geostationary satellites with wide area coverage and fast frequency observations is useful for observing the fast dynamics of the OT life cycle. Therefore, this study intends to analyze the relationship between OT and extreme weather, updraft and thermodynamic conditions of OT when extreme weather occurs, the best objective method for detecting OT in the day time and night time, and the spatiotemporal distribution of OT in the tropical region of Java Island during the 2018-2021 period. Based on visual analysis using visible channel and Himawari 8 sandwich products, 87% of extreme weather events in Java were accompanied by the appearance of OT. It indicates that the presence of the OT pattern is a convection cloud pattern or feature that is closely related to extreme weather events for the Java Island region. The existence of a time lag between the appearance of OT and extreme weather events on Java Island indicates that the OT of convection cloud can be used as a precursor or nowcasting for the appearance of extreme weather. Most of the convective cloud OT features during extreme weather events on Java Island have altitude that were only able to exceed the altitude of the equilibrium level and few were able to exceed the tropopause level of 9 km – 16 km. The difference in atmospheric conditions during extreme weather events on Java Island, which is in the tropics and subtropics, is a strong and unstable convective energy condition characterized by a larger CAPE, as well as unstable KI, LI, SI and TTI values. It is offset by kinematic factors in the form of a weak vertical wind shear (bulk wind shear 0-6 km) and a higher freezing point height. The difference between extreme weather events in the Java Island region and other tropical regions compared to subtropical regions is the strong updraft speed of convection clouds. The IRW Texture COMB algorithm based on the IRW-Texture Gradient modification and the COMB algorithm shows a significant increase in quality for detecting OT and non-OT pixels in Java. Rainy days with rainfall > 50 mm/day are very common in areas with an altitude of > 500 m. On the other hand, the level of convection activity which is indicated by the presence of OT and lightning is significantly reduced in this area. OT of convective clouds appear more frequently during the DJF season and less frequently during the JJA season. OT often appears during the day time and rarely at night time. Most OTs appear in the central part, away from the south and north coasts of Java Island during the day, while OTs that appear near the south and north coasts of Java Island can appear in the morning or afternoon.
Keyword: convective clouds, extreme weather, Overshooting Tops, Himawari 8 Satellite