Judul: Penentuan pilihan lokasi perumahan dalam kaitannya dengan tempat kerja di Kotamadya Manado / Lintang
Abstrak: Metode penelitian didekati dengan stuci kasus di mana penentuan lokasi optimal rumah tinggal didekati dari dua sisi, yaitu sisi permintaan dan sisi penawaran. Sisi permintaan didekati dengan model Ekonomi Konsumen Perumahan, sedangkan sisi penawaran didekati dengan model Ekonomi Produksi Perumahan. Penentuan sampel dilakukan dengan dua cara. Pertama, purposive sampling diterapkan terhadap batas wilayah konsumen, yaitu konsumen dalam kota dan konsumen pinggiran kota. Dalam jarak radius lebih kecil daripada 6 1 dimasukkan dalam konsumen dalam kota, dan dalam jarak radius sama dengan atau lebih besar daripada 6 KM dimasukkan dalam konsumen di pinggiran kota …dst
Keyword: pemukiman perkotaan, model dan lahan alonso, bid rents, konsumen perumahan

Judul: Model pemilihan lokasi pemukiman dan keterkitannya dengan tempat kerja: studi kasus DKI Jakarta dan Bekasi
Abstrak: Tingginya tingkat pertumbuhan penduduk dan peningkatan kegiatan perekonomian masyarakat di wilayah Jabotabek menyebabkan kebutuhan ruang untuk tempat tinggal dan wadah kegiatan perekonomian tinggi dan bersaing ketat. Sehingga masalah yang dihadapi dalam penyediaan pemukiman diperkotaan adalah (a) masalah keterbatasan lahan, (b) tingginya harga lahan dan rumah serta rendahnya daya beli masyarakat berpenghasilan rendah-menengah, (c) belum mantapnya pengaturan dan pelaksanaan tata ruang kota yang sesuai dengan RUTR. Hal ini meyebabkan harga rumah sangat mahal dan tidak terjangkau oleh sebagian besar masyarakat yang menbutuhkan tempat tinggal….dst
Keyword: Tata ruang, Pembangunan wilayah, Konsep von thunen, Konsep ekologi manusia

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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