Judul: Penapisan Senyawa Antibakteri dari Ekstrak Biji Hanjeli (Coix lacryma-jobi) terhadap Escherichia coli dengan Pendekatan Metabolomik.
Abstrak: Biji hanjeli (Coix lacryma-jobi) diduga mengandung senyawa antibakteri. Pada penelitian ini, senyawa antibakteri dalam ekstrak biji diidentifikasi menggunakan kromatografi cair spektrometri massa/spektrometri massa (LCMS/ MS) dan dikelompokkan menggunakan principal component analysis (PCA). Biji hanjeli diekstraksi dengan cara maserasi menggunakan beberapa pelarut, yaitu air, etanol 50%, etanol 96%, dan n-heksana. Aktivitas antibakteri diuji menggunakan metode cakram, Escherichia coli ATCC 25922 sebagai bakteri uji, tetrasiklin sebagai kontrol positif, dan dimetil sulfoksida 20% sebagai kontrol negatif. Ekstrak etanol 50% memiliki aktivitas penghambat E. coli tertinggi. Ekstrak tersebut selanjutnya diidentifikasi menggunakan LC-MS/MS dan senyawa yang diperoleh dikelompokkan menggunakan PCA. Berdasarkan hasil, senyawa tersebut yang diprediksi memiliki aktivitas sebagai antibakteri adalah asam 4-dodesil benzena sulfonat, dodesil sulfat, anhidrida asam asetat, dan asam L-malat.
Keyword: antibakteri, Coix lacryma-jobi, E. coli, LC-MS/MS, PCA

Judul: Analisis Proksimat, Fitokimia, Aktivitas Antioksidan dan Toksisitas Ekstrak Air Biji Hanjeli (Coix lacryma-jobi L.).
Abstrak: Hanjeli merupakan salah satu tanaman serealia lokal yang berpotensi di bidang kesehatan dan medis. Tujuan dari penelitian ini adalah menguji kandungan fitokimia, antioksidan dan toksisitas dari hanjeli sebagai data dasar. Pengujian fitokimia dilakukan secara kualitatif, aktivitas antioksidan diuji dengan metode DPPH dengan variasi konsentrasi ekstrak, uji toksisitas hanjeli menggunakan metode Brine Shrimp Lethality Test. Hasil penelitian menunjukkan bahwa penyosohan dan penepungan biji dengan teknik penepungan basah dan kering berpengaruh terhadap nutrisi, kandungan senyawa bioaktif, aktivitas antioksidan dan toksisitas dari hanjeli. Biji hanjeli mengandung 63% karbohidrat, 16% protein, 6% lemak, sedangkan tepung biji hanjeli mengandung 72% karbohidrat, 17% protein, dan 0% lemak. Biji hanjeli mengandung senyawa alkaloid, saponin, steroid dan triterpenoid. Aktivitas antioksidan tertinggi terdapat pada tepung hanjeli dengan teknik penepungan kering, dengan nilai IC50 sebesar 9515 ppm yang termasuk dalam kategori antioksidan sangat rendah. Nilai LC50 hanjeli berada pada kisaran 100-500 ppm dan termasuk dalam kategori toksik sedang yang memiliki potensi senyawa bioaktif cukup tinggi.
Keyword: hanjeli, fitokimia, antioksida, toksisitas

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
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