Judul: Desain Produk Minyak Pala Terpeneless
Abstrak: Minyak pala terpeneless merupakan produk turunan dari minyak pala yang memiliki stabilitas dan kelarutan dalam alkohol lebih baik sehingga memiliki nilai jual yang lebih tinggi dibandingkan minyak pala. Di Indonesia belum ada perusahaan yang memproduksi minyak pala terpeneless. PT Alam Indonesia Raharja (AIR) tergerak untuk mengembangkan usahanya di bidang minyak pala terpeneless. Namun, PT AIR belum memiliki rancangan untuk membuat minyak pala terpeneless. Desain produk menjadi salah satu solusi yang dapat membantu mitra menyelesaikan permasalahan tersebut. Ada empat aspek penting dalam mendesain produk minyak pala terpeneless, yaitu spesifikasi bahan baku atau pemilihan bahan baku, spesifikasi produk, sertifikat halal dan sertifikat natural. Dalam penelitian ini, keempat aspek tersebut akan dibahas dan dirancang melalui studi literatur dari berbagai sumber informasi yang tersedia., Terpeneless nutmeg oil is a derivative product of nutmeg oil which has better stability and solubility in alcohol so that it has a higher selling value than nutmeg oil. In Indonesia, there is no company that produces terpeneless nutmeg oil. PT Alam Indonesia Raharja (AIR) was moved to develop its business in the field of terpeneless nutmeg oil. However, PT AIR did not have a design to make terpeneless nutmeg oil. Product design is one of the solutions that can help partners solve this problem. There are four important aspects in designing terpeneless nutmeg oil products, namely raw material specifications or raw material selection, product specifications, halal certificates and natural certificates. In this research, these four aspects will be discussed and designed through literature studies from various available sources of information.
Keyword: Product Design, Nutmeg Oil, Terpeneless Nutmeg Oil, Halal Certificate, Natural Certificate

Judul: Perancangan Alat dan Tata Letak Pabrik Industri Minyak Pala Terpeneless di PT. Alam Indonesia Raharja
Abstrak: Minyak pala terpeneless yang dimurnikan menggunakan vacuum distiller bertujuan untuk mempersingkat waktu proses pemurnian sehingga minyak atsiri yang diperoleh memiliki kandungan miristisin yang tinggi. Sehingga komponen miristisin digunakan sebagai indikator penentu kualitas minyak pala terpeneless. Hal ini yang membuat PT. Alam Indonesia Raharja tertarik dalam menghadapi permintaan yang tinggi terkait minyak pala dan minyak pala terpeneless. Penelitian ini berfokus membantu PT. Alam Indonesia Raharja dalam membuat perancangan alat dan tata letak industri minyak pala terpeneless. Metode penelitian yang digunakan menggunakan pendekatan kuantitatif melalui wawancara dan observasi langsung kepada informan yang nantinya berguna untuk perancangan alat dan tata letak industri minyak pala terpeneless. Alat distilasi vakum yang dibutuhkan berkapasitas 100 kg/batch. Untuk dimensi reboiler tank yaitu panjang 1.789 m, dan diameter 1,193 m. Kolom distilasi yaitu untuk panjang 2,5 m, diameter 0,202 m. Untuk dimensi kondensor, panjang 1,4 m dan diameter 0,185. Tata letak industri minyak pala terpeneless menggunakan metode Computerized Relationship Layout Planning (CORELAP). Pada Perancangan tata letak, dibutuhkan 9 ruang yang meliputi ruang produksi dan ruang nonproduksi. Untuk perhitungan Total Closeness Rating (TCR), untuk nilai TCR tertinggi yaitu ruang produk jadi sehingga menjadi pusat tata letak pabrik minyak pala terpeneless. Untuk perhitungan area masing-masing departemen, dibutuhkan 200 m²., Terpeneless nutmeg oil is refined using a vacuum distiller to shorten the refining process time so that the essential oil obtained has a high myristicin content. So that the myristicin component is used as an indicator of the quality of terpeneless nutmeg oil. This is what makes PT Alam Indonesia Raharja interested in facing the high demand for nutmeg oil and terpeneless nutmeg oil. This research focuses on helping PT Alam Indonesia Raharja in making the design of tools and layout of the terpeneless nutmeg oil industry. The research method used uses a quantitative approach through interviews and direct observation to informants which will be useful for designing tools and layout of the terpeneless nutmeg oil industry. The vacuum distillation equipment needed has a capacity of 100 kg/batch. The dimensions of the reboiler tank are 1.789 m long, and 1.193 m in diameter. The distillation column is for a length of 2.5 m, diameter 0.202 m. For the dimensions of the condenser, the length is 1.4 m and the diameter is 0.185. The layout of the terpeneless nutmeg oil industry uses the Computerized Relationship Layout Planning (CORELAP) method. In the layout design, 9 spaces are needed which include production space and non-production space. For the calculation of Total Closeness Rating (TCR), the highest TCR value is the finished product room so that it becomes the center of the terpeneless nutmeg oil factory layout. For the calculation of the area of each department, 200 m² is required.
Keyword: Terpeneless nutmeg oil, Layout, Equipment design

Judul: Mathematical model of Hematopoietic Stem Cell in Chronic Myelogenous Leukemia with and without Therapy
Abstrak: Leukemia or blood cancer is a diverse group of neoplastic disease, characterized by the multiplication of abnormal leukocytes or malignant transformation of blood-forming cells in bone marrow and lymphoid tissues. One of the most common types of leukemia is Chronic Myelogenous Leukemia (CML), which is usually diagnosed by the presence of certain chromosomal abnormalities, the so-called Philadelphia chromosome (Ph). One of the treatments of CML is Granulocyte Colony-Stimulating Factor (G-CSF). In this paper, we discuss two Hematopoietic Stem Cell (HSC) models, i.e. HSC without treatment and HSC with G-CSF treatment. The model of HSC without treatment included three equations representing the dynamics of HSC, leukocyte and platelet. Whereas, the model of HSC with G-CSF treatment includes the previous three equations and adds two more equations representing G-CSF injection and G-CSF circulation. The stability behavior of the system approaching the equilibrium points in the simulation study is carried out using Mathematica 7.0. The simulation results show that the G-CSF treatment can successfully decrease the number of HSC, which means reducing the CML.
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