Judul: The Effectiveness Extract Combination Skunk Vine (Paederia foetida L.) and Gum Arabic as an Antidiarrheal in Mice (Mus musculus)
Abstrak: Daun sembukan telah lama digunakan oleh masyarakat untuk pengobatan secara tradisional, namun penelitian tentang khasiatnya sebagai antidiare masih sangat sedikit. Tujuan penelitian ini yaitu untuk mengetahui aktivitas antidiare kombinasi ekstrak daun sembukan dan gum arab dengan metode proteksi intestinal dan transit intestinal, serta menentukan takaran dosis yang efektif pada mencit. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi enam kelompok. Perlakuan kelompok terbagi menjadi kontrol negatif (1% Tween-80), kontrol positif (Loperamide HCl), dan empat perlakuan kombinasi ekstrak daun sembukan dan gum arab (12,5%, 25%, 50%, dan 100%) yang diberikan secara oral. Parameter yang diamati yaitu frekuensi defekasi, konsistensi feses, dan rasio lintasan marker usus. Disimpulkan bahwa dari kedua metode, potensi antidiare terbaik ditemukan pada konsentrasi 12,5%., Skunk vine have long been used by the community for traditional medicine, but research on its efficacy as an antidiarrheal is still very little. The purpose of this study was to determine the antidiarrheal activity of the combination of skunk vine extract and gum arabic with intestinal protection and intestinal transit methods, and to determine the effective dose in mice. This study used 30 mice which were divided into six groups. The treatment group was divided into negative control (1% Tween-80), positive control (Loperamide HCl), and four combination treatments of skunk vine extract and arabic gum (12.5%, 25%, 50%, and 100%) given orally. The parameters observed were the frequency of defecation, stool consistency, and the ratio of intestinal marker trajectories. It was conclude that of the two methods, the best antidiarrheal potency was found in 12.5% treatment.
Keyword: antidiare, daun sembukan, gum arab, proteksi intestinal, transit intestinal

Judul: Efficacy of Gum Arabic Infusion as an Antidiarrheal in Mice (Mus musculus)
Abstrak: Gum arab digunakan oleh masyarakat Indonesia untuk mengobati beberapa penyakit. Beberapa senyawa aktif antidiare seperti saponin, tanin, dan flavonoid terkandung dalam gum arab. Penelitian ini bertujuan untuk mengetahui efikasi antidiare infusa gum arab menggunakan metode proteksi intestinal dan transit intestinal serta menentukan konsentrasi yang paling efektif pada mencit. Penelitian ini menggunakan tiga puluh ekor mencit jantan yang dibagi menjadi enam kelompok yang terdiri dari kelompok kontrol negatif (tween 80 [1%]), kontrol positif (loperamide HCI), dan empat kelompok perlakuan infusa gum arab dengan konsentrasi bertingkat (12,5 %, 25%, 50%, dan 100%). Hasil metode proteksi intestinal menunjukkan bahwa semua kelompok konsentrasi infusa gum arab memiliki efek antidiare. Hasil metode transit intestinal menunjukkan hanya 12,5% kelompok konsentrasi yang memiliki aktivitas antidiare, sehingga disimpulkan konsentrasi 12,5% memiliki efek antidiare terbaik, Gum arabic is used by Indonesians to treat several diseases. Several active antidiarrheal compounds such as saponins, tannins, and flavonoids are present in gum arabic. This study aimed to determine the antidiarrheal efficacy of gum arabic infusion using intestinal protection and intestinal transit methods and determine the most effective concentrations in mice. This study used thirty male mice, which were divided into six groups consisting of a negative control (tween 80 [1%]), a positive control (loperamide HCI), and four treatment groups of gum arabic infusion with graded concentrations (12,5%, 25%, 50%, 100%). The intestinal protection methods result showed that all gum arabic infusion concentration groups had antidiarrheal effects. The intestinal transit methods showed that only 12,5% concentration group had antidiarrheal activity, it was concluded that concentration of 12,5% had the best antidiarrheal effect.
Keyword: antidiarrheal, gum arabic, infusion, intestinal protection, intestinal transit

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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