Judul: Designing a Custom Coffee Order Website Business Model in Bogor City
Abstrak: Biji kopi merupakan bahan baku utama bagi kedai kopi yang sangat mempengaruhi kualitas dan variasi cita rasa minuman kopi. Mayoritas kedai kopi melewati proses panjang dalam mencari bahan baku mulai dari keterbatasan informasi, ketidakpastian kualitas, ketidakkonsistenan cita rasa, dan lokasi jauh. Penelitian ini bertujuan menganalisis permasalahan dan menemukan solusi yang dihadapi para kedai kopi, merancang prototipe, dan model bisnis “Explorer Coffee” online store penyedia biji kopi berbasis website dengan pendekatan design thinking. Online store “Explorer Coffee” yang melayani kustomisasi pembelian kopi dapat menjadi solusi dari permasalahan kedai kopi. Menawarkan seluruh kebutuhan kopi dengan berbagai layanan kustomisasi kopi mulai dari biji hiaju kopi (greenbearn), sangrai kopi (roasting), biji kopi sangrai (roasted been), dan biji kopi sangrai berdasarkan cita rasa yang dicari. Solusi ini dapat diakses mudah melalui website mobile friendly yang dapat diaskse dari mana saja kapan saja., Coffee beans are the primary raw material for coffee shops, greatly influencing the quality and flavor variety of coffee drinks. Most coffee shops undergo a lengthy process in sourcing raw materials, starting from limited information, quality uncertainty, flavor inconsistency, to distant locations. This research aims to analyze the problems faced by coffee shops, find solutions, design prototypes, and establish the business model of "Explorer Coffee," an online store providing coffee beans based on a website with a design thinking approach. The "Explorer Coffee" online store, which offers customized coffee purchases, can serve as a solution to coffee shop issues. It provides all coffee needs with various customization services including green bean, roasting, roasted bean, and roasted bean based on desired flavor profiles. This solution is easily accessible through a mobile-friendly website that can be accessed from anywhere at any time.
Keyword: Coffee Beans, Websit, online store, Kedai Kopi, Biji kopi, Online Store, website, Supplier, Design thinking, Supplier, Design thinking, Coffee Shop

Judul: Designing Digital Interaction Education of Local Specialty Coffee using Double Diamond Design Process
Abstrak: Indonesia memiliki 20 jenis specialty coffee dengan karakteristik yang bervariasi dari berbagai daerah. Penilaian konsumen terhadap rasa, minat untuk beli, dan preferensi meningkat ketika diberikan informasi subjektif mengenai kopi yang akan dikonsumsi. Informasi mengenai kopi yang sulit dipahami oleh konsumen kopi akan menjadi halangan dalam mencoba kopi baru. Eksperimen yang berhubungan dengan interaksi dalam dunia kopi sudah dilakukan sebelumnya, dalam bentuk robot pemberi rekomendasi kopi dan nampan yang memuat informasi kopi yang diseduh. Tujuan dari penelitian ini adalah merancang dan membuat interaksi baru yang bertujuan meningkatkan minat dan edukasi specialty coffee lokal. Penelitian ini menggunakan metode double diamond yang berisi empat fase. Fase discover untuk mencari data melalui survei dan wawancara. Fase define untuk menentukan masalah inti melalui metode affinity diagram. Fase develop untuk menghasilkan ide-ide melalui metode brainstorming dan diskusi. Fase deliver untuk merancang ide lebih jauh yang memiliki prioritas tinggi dan yang paling sesuai penerapan terhadap masalah yang ingin diselesaikan., Indonesia has 20 types of specialty coffee with differing characteristics that originate from different areas. Consumers' judgment of taste, willingness to buy, and preference increases when given subjective information of the coffee that will be consumed. Information about coffee that is difficult to understand by consumers may be an obstacle that hinders them from trying new types of coffee. Experiments about interaction in the coffee sector has been done before, such as a robot coffee recommender and a tray that gives info on the coffee consumed. The goal of this research is to design and develop a new interaction with the goal of increasing interest and education about local specialty coffee. This research uses the Double Diamond method that has four phases. Discovery phase is to look for data through a survey and interviews. Define phase is to look for the central problem through the affinity diagram method. Develop phase is to generate ideas for the prototype using brainstorming and discussion method. Deliver phase is to further design the ideas that have high priority to develop and the applicable ones to reach a solution for the problems found.
Keyword: design interaction, double diamond, specialty coffee

Judul: Virological and Immunological Studies of Dengue Virus Infection in Pigtail Macaques (Macaca nemestrina).
Abstrak: Dengue virus infections have caused a major public health problem in tropical and sub-tropical countries. The geographical distribution, the frequency of epidemic cycle and the number of cases have been increasing at an alarming rate and highlighted the urgency of DEN vaccine (WHO 2005; Raviprakash et al. 2009). The clinical manifestations of DEN infections range from mild dengue fever (DF) with high fever, headache, rash, and bone and muscle pain up to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with evidence of thrombocytopenia, bleeding, plasma leakage and shock. The severe manifestation cause a high mortality rate particularly in children (WHO 2005). Since the 1980s, epidemiological data revealed that 85% of DHF and DSS were heterologous secondary infections and immunopathological response to heterologous secondary infection has been hyphothesized leading to DHF pathogenesis (Halstead 1983). Antibody produced following primay DEN infection confers the protection to homologous infection, however, heterologous secondary infection may still occur. The pre-existing, non-neutralizing antibodies binds DEN viruses and these complexes, then bind the target cells via the FcγRI and FcγII, resulting in increased viral load, shortened incubation period and increased disease severity (Fink et al. 2006). Meanwhile, DEN specific CD4+ and CD8+ T lymphocytes are suggested to have a low binding affinity for the current serotype, and consequently, inefficient to clear the infection (Fink et al. 2006). The limitations of DEN study in human have hampered the understanding of these two components of adaptive immunity, antibody and T lymphocyte, in the pathogenesis of DHF.
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