Judul: Kemampuan Netralisasi Antibodi Spesifik Avian Influenza H5 Terhadap Beberapa Virus H5N1 Isolat Lapang
Abstrak: Avian Influenza (AI) is well known as Avian flu, Fowl pest, Fowl plaque, or Flu burung, caused by influenza virus type A. This virus is belonged to Orthomyxoviridae and could infect many kind of species such as bird, pig, horse, cat, as well as human. Vaccination is applied to control the disease using inactivated vaccine, which induced the specific antibody against H5 antigen. Passive immunization using specific antisera against H5 antigen is thought to be usefull in controlling the disease especially in the treatment of infected host. In this experiment the neutralization ability of specific antisera against H5 were studied using various field viral isolates subtype H5N1. Antisera was developed in Cavia porcellus which vaccinated with AI subtype H5N1 in activated vaccine. The titre of antisera obtained is 28 used HI test. Four AI virus subtype H5N1 isolates from 2003 to 2006 agains viral were we as tested virus. The neutralization test showed that the sera were able to neutralizing 10 4 EID50 AI virus H5N1 with neutralization index range between 1,1– 1,3. The result indicated that the specific antisera had the neutralization potency to the field virus.
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Judul: Kemampuan IgG Anti Avian Influenza H5N1 Asal Kolostrum Sapi dalam Menetralkan Virus Avian Influenza H5N1 Isolat Indonesia.
Abstrak: Avian influenza (AI) H5N1 adalah salah satu penyakit yang bersifat zoonosis. Vaksin AI H5N1 untuk manusia hingga kini belum ditemukan. Imunoterapi menggunakan IgG anti H5N1 asal kolostrum sapi diharapkan menjadi solusi untuk mencegah penyakit AI pada manusia. Tujuan dari penelitian ini adalah mengevaluasi kemampuan IgG anti H5N1 asal kolostrum sapi dalam menetralisasi virus AI H5N1 isolat Indonesia 2013. Kemampuan netralisasi IgG anti H5N1 diukur berdasarkan nilai indeks netralisasinya. Virus AI H5N1 isolat Indonesia dititrasi dengan Uji Embrio Infectious Doses50 (EID50) sebelum dan setelah ditambahkan suspensi IgG anti AI H5N1 menggunakan media telur ayam berembrio. Berdasarkan hasil titrasi virus tersebut dihitung indeks netralisasinya. Hasil penelitian menunjukkan bahwa, IgG H5N1 asal kolostrum sapi belum mampu menetralisasi virus AI H5N1 isolat Indonesia 2013 dengan optimal dengan indeks netralisasi sebesar 1.07. Diduga rendahnya kemampuan netralisasi ini karena adanya perbedaan homologi strain antara antibodi IgG dengan virus yang diuji.
Keyword: avian influenza, IgG, kolostrum sapi, uji netralisasi, uji titrasi EID50

Judul: Pemodelan Proses Layanan Bisnis Untuk Routing Dan Costing Transportasi Laut Minyak Sawit: Studi Kasus Di PT. X.
Abstrak: One of business service of maritime transport is to provide ship rental for the tenants to deliver their products to the destination. Main focuses of problem this work are determining routing and costing and time efficient so it can arrives on time. The company needs to determine the route, operating costs are required, the distance to be taken and the optimization time. The purpose of this study was to get the optimal path, determine the operating costs per voyage the ship and determine the rent. The Modeling shows the determination of the route the ship can be done using the Kruskal’s algorithm while the modeling for the cost of rent shows that the magnitude of the rent is affected by the size of cargo ships and operating costs are calculated after the ship sailed.
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