Judul: Penghambatan Enzim Siklooksigenase-2 oleh campuran nanopartikel ekstrak Suruhan (Peperomia pellucida) dan Jahe Merah (Zingiber officinale)
Abstrak: Both suruhan (Peperomia pellucida) and red ginger (Zingiber officinale) were known to inhibit cyclooxygenase-2 but, the mixture of these two has a low inhibition of cyclooxygenase-2. The aim of this research is to test the potency of suruhan, red ginger, and its mixture in nanoparticle as a cyclooxygenase-2 inhibitor. Groups were divided into suruhan nanoparticle, red ginger nanoparticle, and suruhan-red ginger nanoparticle 1:1, 2:1, and 1:2. Nanoparticle was made using homogenation and ultrasonication. The inhibitory effect was analyzed using Enzyme-linked Immunosorbent Assay (ELISA) principle. The average size of suruhan nanopaticle was 90.61 nm and the Polidispersity Index was 0.22. Average size of red ginger nanoparticle was 173.46 nm and IP was 0.17. Maximum inhibition of cyclooxygenase-2 by nanoparticle of red ginger was 73.82% at 75 μg/mL, and 22.99 % by its mixture at 175.75 μg/mL. Nanoparticle of suruhan did not have an inhibitory effect, however its mixture with nanoparticle of red ginger (1:2) can inhibit cylooxygenase-2.
Keyword: Bogor Agricultural University (IPB), suruhan, red ginger, nanoparticle, inflammation, cyclooxygenase-2

Judul: Daya Inhibisi Ekstrak Rimpang Jahe Merah dan Kulit Kayu Manis terhadap Aktivitas Enzim Siklooksigenase 2 dan Enzim Xantin Oksidase Secara In Vitro
Abstrak: Red ginger and cinnamon are medicine plants which can be used as anti-inflammation and lowering uric acid level in blood. In this study, water and ethanol extracts of red ginger root and cinnamon bark have been assayed for phytochemical constituent, toxicity by brine shrimp lethality test, and in vitro inhibition of cyclooxygenase 2 and xanthine oxidase activities. Diclofenac, ibuprofen and allopurinol were used as positive control. Based on phytochemical assay, water and ethanol extracts of red ginger root contained alkaloids, steroids, and flavonoids, while its water extract of cinnamon bark contained kaloids, triterpenoids, saponins, flavonoids, and tannins. The result of probit analyses of water and ethanol extracts of red ginger root and cinnamon bark showed that their LC50 values were 144 ppm, 108 ppm, 125 ppm, and 107 ppm, respectively. Ethanol extract of red ginger root showed very low inhibitory effect to cyclooxygenase 2 activity (23.81%) as compared to diclofenac (95,43%) and ibuprofen (93,59%). Water and ethanol extracts of cinnamon bark that have inhibitory effect more than 50% to xanthine oxidase were, 54.64% and 56.80%, with their IC50 values of 70 ppm and 63 ppm, respectively. Allopurinol exhibited the highest inhibitory effect (97.91%). The value of inhibitory effect showed that ethanol extract of red ginger root have low potential as inhibitor to cyclooxygenase 2 and rheumatoid drugs; water and ethanol extracts of cinnamon bark can be considered as potential as inhibitor of xanthine oxidase and can be used for uric acid drugs.
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Judul: Desain Sistem Transfer Energi Nirkabel Berbasiskan Tesla Coil
Abstrak: Tesla coil merupakan alat yang ditemukan oleh Nikola Tesla yang dapat mentransmisikan daya tanpa kabel dengan memanfaatkan prinsip induksi elektromagnetik. Pada penelitian ini dibuat sebuah prototype Tesla Coil dengan menggunakan transistor C1970 dan receiver menggunakan rangkaian LC. Identifikasi alat meliputi pengaruh daya input transmitter terhadap receiver, bentuk signal yang dipancarkan transmitter, pengaruh jarak transmitter dan receiver, nilai efisiensi serta efek alat terhadap perangkat lain. Hasil pengamatan menunjukkan bahwa semakin besar daya input maka semakin besar daya yang dipancarkan oleh transmitter. Bentuk sinyal yang dipancarkan oleh transmitter berupa gelombang listrik AC sinusoidal dengan frekuensi ~2.9 MHz. Semakin jauh jarak receiver terhadap transmitter maka semakin kecil amplitudo gelombang AC yang diterima oleh receiver, menyebabkan semakin kecil daya yang diterima oleh receiver. Adapun nilai efisiensi terbesar penangkapan daya oleh receiver yaitu sebesar 0.00516 % serta terdapat gangguan pada alat-alat tertentu seperti monitor komputer dan radio.
Keyword: rangkaian LC, receiver, tesla coil, transistor C1970, transmitter