Judul: Impact of Macroeconomic Factors on Underpricing: Case of Indonesia Stock Exchange
Abstrak: The stock market is one of the alternatives chosen by companies to meet their funding needs. The first offering of a company's shares through the stock market to investors is called an Initial Public Offering. At the time of initial public offering, underpricing often occurs when the initial stock price on the primary market is lower than the stock price on the secondary market which will disadvantage the company because the collected funds are not maximum. This research aims to analyze the effect of macroeconomic factors on underpricing in companies conducting IPOs listed on the Indonesia Stock Exchange in 2010 to 2020. Using Regression Linear Analyze we found that macroeconomic variables as Inflation, IDX COMPOSITE INDEX, and GDP significantly affecting underpricing on IPO in Indonesia Stock Exchange for 2010 to 2020., Pasar modal menjadi salah satu alternatif yang dipilih oleh perusahaan untuk memenuhi kebutuhan dananya. Penawaran pertama saham perusahaan melalui pasar modal kepada investor umum disebut dengan Initial Public Offering. Pada saat melakukan penawaran perdana ini sering terjadi underpricing, yaitu harga saham perdana lebih rendah daripada harga saham di pasar sekunder yang akan merugikan perusahaan karena dana yang diterima tidak maksimum. Penelitian ini bertujuan untuk menganalisis pengaruh faktor makroekonomi terhadap tingkat underpricing pada perusahaan yang melakukan IPO terdaftar di Bursa Efek Indonesia tahun 2010-2020. Dengan menggunakan Analisis Regresi Linier ditemukan bahwa variabel makroekonomi yaitu Inflasi, IHSG, dan PDB berpengaruh signifikan terhadap underpricing pada IPO di Bursa Efek Indonesia tahun 2010 hingga 2020.
Keyword: Initial Public Offering, Stock Market, Macroeconomy, Underpricing

Judul: Analisis Pengaruh Valuasi Harga Saham, Kinerja Keuangan, dan Informasi non-Keuangan terhadap Underpricing pada Penawaran Saham Perdana di Indonesia
Abstrak: Penawaran saham perdana atau IPO merupakan alternatif pendanaan yang sering dipilih oleh perusahaan. Permasalahan yang sering terjadi pada masa IPO adalah underpricing yang menyebabkan kerugian pada perusahaan karena dana IPO yang diterima tidak maksimum. Penelitian ini bertujuan untuk menganalisis pengaruh valuasi harga saham, kinerja keuangan, dan informasi non-keuangan terhadap underpricing pada perusahaan yang melakukan IPO terdaftar di Bursa Efek Indonesia tahun 2012-2022. Penelitian ini dilaksanakan pada April 2022 – Mei 2023 dan data penelitian diperoleh dari Bursa Efek Indonesia. Metode penelitian yang digunakan ialah analisis regresi linier berganda dengan variabel mencakup Price to Book Value (PBV), Price to Earning Ratio (PER), Debt to Equity Ratio (DER), Return on Equity (ROE), Reputasi Underwriter (UDW), dan Reputasi Auditor (AUD). Berdasarkan hasil penelitian, ditemukan bahwa variabel PBV dan UDW berpengaruh negatif terhadap underpricing, sedangkan PER berpengaruh positif terhadap underpricing. Adapun pada variabel lainnya, yakni DER, ROE, dan AUD tidak ditemukan pengaruh yang signifikan terhadap underpricing.
Keyword: initial public offering,, stock price, underpricing

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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