Judul: Spatial palnning model for coastal area. case study: Kabupaten Bekasi North Coastal Area.
Abstrak: The propose of the study is to purposes as spatial planning model for coastal areas, integrating land and marine aspect. The comp lexity of issues in coastal areas such as heterogentiy of life, potentials of economi c resources, and tobe explored and developed. Coastal areas as the basic matrix for development i s dynamic, difficult for clear and exact delineation, and do not have clear manage ment boundaries. The approach employed to formulate the spatial plan ning model for coastal areas is a descriptive method both quantitative and quali tative. The dynamics taking place in coastal areas require different planning approach from a land based spatial planning, and the main indicators are its carrying capacity, land suitability and economic value of each land utilitation. These indicators also be app lied in the coastal zone spatial planning model purposed in this study, with the n ecessary modification as appropriate in coastal zone.
Keyword: Land Carrying Capacity, Coastal Zone Land Utilization, Coastal Zone Characteristics

Judul: Management Planning at Western Coastal Area of Kabupaten Pandegiang - Banten Province
Abstrak: Exploration and exploitation of coastal and marine resources need to be done properly based on integrated regional management planning. Since western part of coastal area in Kabupaten Pandeglang - Banten Province has experienced high environmental pressures due to intensive utilization, it needs to be managed integrated to achieve optimal results. The objectives of this research are to analyze coastal and marine resource characteristics, to develop a zonation, management zones and strategies, and management strategies for western part of coastal area in Kabupaten Pandeglang. The benefits of this research are optimal management and increasing community prosperity and local government of Kabupaten Pandeglang. The research was done in five sub-districts in Kabupaten Pandeglang consisting of Kecamatan Labuan, Jiput, Pagelaran, Panimbang, and Cigeulis. The materials and data used were maps, primary and secondary data. The equipments used in the research were equipments for water and soil sampling, laboratory analysis, coastal ecosystem observations, and location positioning. The methods consist of natural resources valuation, development of zonation using geographic information system, development of management zones and strategies, and strategies for integrated coastal area management. The results show that land and water resources quality is low, marine resources quality is low due to marine ecosystem pollution and degradation. The beach types are dominantly sand beach along Kecamatan Labuan, mud sediment beach along Kecamatan Pagelaran, and coral reef bed along Kecamatan Panimbang and Cigeulis. The results of zonation show zones of settlement in all study area, plantation in Kecamatan Labuan, Jiput and Cigeulis, forest in Kecamatan Labuan, Jiput and Cigeulis, wetland agriculture in Kecamatan Labuan, Jiput, Pagelaran and Panimbang, industry in Kecamatan Labuan, Pagelaran and Panimbang. Spices zone is in Kecamatan Jiput, Panimbang and Cigeulis. Fish pond culture is in Kecamatan Panimbang, while mangrove and silvo-fishery and coastal tourism are in Kecamatan Labuan, Pagelaran, Panimbang and Cigeulis. Marine tourism, coral reef, floating net (KJA) and sea grass cultures are in Kecamatan Labuan, Pagelaran, Panimbang and Cigeulis. Preservation zone is to be managed stt-ictly only for science and research purposes, conservation zone is for limited utilization, and development zone is to be managed for optimal economic development by considering commodity, sector and infrastructure which are existing and being developed. Strategies for western coastal zone management in Kabupaten Pandeglang include increasing of existing probabilities in line with decreasing weakness and challenges.
Keyword: zonation, geographic information system, integrated coastal management, preservation, conservation, development

Judul: Peran Antibodi Kuning Telur (IgY) Sebagai Anti Adhesi dan Opsonin Untuk Pencegahan Serangan Mutan Streptococcus Serotipe d (Streptococcus Sobrinus)
Abstrak: Ayam petelur memiliki peran penting sebagai penghasil antibodi poliklonal. Antibodi ayam atau dikenal dengan imunoglobulin Y (IgY) dapat dipurifikasi dari kuning telur. Biaya untuk memproduksi IgY relatif lebih murah daripada antibodi mamalia karena biaya pemeliharaan ayam tidak mahal, relatif lebih mudah dan cepat menghasilkan telur. Penelitian ini bertujuan untuk mempelajari peran IgY spesifik MS serotipe d (Streptococcus sobrinus) (IgY-Ss) sebagai anti adhesi dan opsonin pada sel epitel pipi. IgY spesifik dikoleksi dari telur ayam Single Comb Brown Leghorn yang telah diimunisasi dengan antigen utuh S. sobrinus. Imunisasi diaplikasikan secara intravena dengan dosis antigen utuh S. sobrinus 0,5 ml (109CFU) selama tiga hari berturut-turut pada minggu pertama . Kemudian dilakukan pengulangan imunisasi (booster) sebanyak tiga kali dengan interval waktu seminggu secara intramuskular dengan dosis antigen utuh S. sobrinus 1 ml (109CFU) dalam Freud’s adjuvant complete pada minggu kedua dan dalam Freud’s adjuvant incomplete pada minggu ketiga dan keempat. Uji agar gel presipitasi (AGP) dilakukan untuk mengetahui terbentuknya IgY spesifik S.sobrinus (IgY-Ss). Ayam yang serum dan telurnya positif pada uji AGP kemudian telurnya di koleksi untuk dilakukan ekstraksi. Ekstraksi IgY-Ss dari kuning telur menggunakan metode PEG-amonium sulfat kemudian dipurifikasi dengan fast protein liquid chromatography. Konsentrasi IgY-Ss yang telah dimurnikan dihitung dengan spektrofotometer UV. Kemudian berat molekul IgYSs ditentukan dengan metode SDS Page dan menggunakan pewarnaan Commasie blue. Aktifitas biologis IgY-Ss sebagai anti adhesi dipelajari dengan assay adhesi secara in vitro menggunakan sel epitel pipi manusia. Assay adhesi dilakukan dengan dosis IgY-Ss 100 μg . Peran IgY-Ss sebagai opsonin dipelajari dengan assay fagositosis menggunakan dosis IgY sebesar 100 μg. Hasil penelitian yang diperoleh adalah IgY-Ss telah terbentuk dalam serum pada minggu kelima, sedangkan dalam telur pada minggu kesembilan setelah imunisasi pertama. Pre-inkubasi 100 μg IgY-Ss pada sel bakteri dan epitel pipi mampu menurunkan nilai adhesi dari 39,9 sel bakteri/ sel epitel pipi menjadi 30,7 sel bakteri/ sel epitel pipi. Opsonisasi dengan 100 μg IgY-Ss tidak meningkatkan aktifitas fagositosis namun hanya meningkatkan kapasitas fagositosis makrofag dari 1,6 sel bakteri/ makrofag menjadi 5,17 sel bakteri/ makrofag. Kesimpulan dari penelitian ini adalah ayam mampu memproduksi IgY spesifik anti S. sobrinus (IgY-Ss) pada serum dan kuning telur. Proses opsonisasi IgY-Ss pada S. sobrinus dapat meningkatkan kapasitas fagositosis. Preinkubasi IgY-Ss pada S. sobrinus (107 CFU/ ml) dan sel epitel pipi (105 sel) dapat mengurangi adhesi bakteri tersebut pada sel.
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