Judul: Formula Campuran 3 Daun Tanaman Obat sebagai Penghambat Tirosinase serta Sidik Jari Kromatogramnya
Abstrak: Potensi formula campuran 3 daun tanaman obat (A, B, dan C) dalam mengurangi hiperpigmentasi kulit ditetapkan berdasarkan aktivitas inhibitor tirosinase dan antioksidan. Daun diekstraksi dengan maserasi menggunakan etanol 50%. Ketiga ekstrak tanaman dikombinasikan berdasarkan bobot menggunakan simplex centroid design. Formula diuji kadar fenolik total, flavonoid, aktivitas inhibitor tirosinase, dan antioksidan 2,2-difenil-1-pikrilhidrazil (DPPH). Ekstrak tunggal daun A menunjukkan aktivitas terbaik sebagai inhibitor tirosinase (IC50 monofenolase 214.39 μg/mL; IC50 difenolase 274.40 μg/mL) dan antioksidan (IC50 56.94 μg/mL). Ada 4 noda aktif dengan substrat L-tirosina dan 3 noda aktif dengan substrat 3,4-dihidroksifenilalanina (L-DOPA) yang diperoleh dari pola sidik jari kromatografi lapis tipis ekstrak tunggal daun A. Sidik jari ekstrak tersebut dianalisis menggunakan etil asetat:kloroform sebagai fase gerak terbaik.
Keyword: antioksidan, hiperpigmentasi, inhibitor tirosinase, sidik jari

Judul: Aktivitas antijerawat formula campuran temu lawak dan meniran serta penentuan sidik jari kromatografinya
Abstrak: Anti-acne activity of extracts from C. xanthorriza and P. niruri has been analyzed through antioxidant and antibacterial activity assays. Extraction process was conducted by two different maceration methods, Indonesian and traditional chinese medicine (TCM) with ethanol 96% as the solvent. Formula 6 (2/3 C. xanthorriza:1/6 P. niruri:1/6 starch) was the most active anti-acne formula with IC50 of antioxidant values of 93.17 ppm, the minimum inhibitory concentration against Staphylococcus epidermidis was 0.25 mg/mL, and the minimum bactericidal concentration was 0.50 mg/mL. Moreover, TCM maceration was better than the Indonesian method in terms of antioxidant and antibacterial activities. Fingerprint analysis of formula was undertaken using thin layer chromatography. The optimum mobile phase was chloroform that gave 9 bands. Further, the (HPLC) analysis with C18 as column and gradient of acetonitrile and water as the mobile phase showed that the peak area of phyllanthin and curcumin increased when the standard compounds were added into the sample.
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Judul: Pengukuran Kecepatan Gelombang Seismik Laut 2D menggunakan Prestack Time Migration dengan Metode Kirchhoff
Abstrak: Seismic method is a method used in geophysics to study the structure of earth surface and below using sounds. Seismic waves are emitted by the transmitter into the sea to the subsurface ocean floor. Reflected wave is returned subbottom to the hydrophone and contains information on the elastic parameters of the subbottom. The method used in this study is using the Prestack Time Migration (PSTM) with the Kirchhoff method has the advantage to increase the Signal/Noise data and be able to improve data quality including time, angles, and distances. This study was conducted to analyze the speed of default parameters and the root mean square (rms) using Prestack Kirchhoff Time Migration method. Cross-sectional results of the two treatments were applied in seismic data line 13-1 in the Gulf of Bone waters, South Sulawesi. In the seismic section are sequence boundaries of toplap, downlap, normal and reverse faults event. Based on the results obtained, cross prestack time migration using the rms velocity analysis (picking velocity) gives better results compare to the cross section of prestack time migration using default parameters.
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