Judul: Pembuatan Nata De Coco dari Beberapa Konsentrasi “Skim” Santan dan Sukrosa
Abstrak: Diversifikasi produk merupakan salah satu cara untuk meningkatkan nilai tambah suatu komoditi, termasuk diantaranya komoditi kelapa. Nata De Coco adalah salah satu diversifikasi produk kelapa. Permintaan Nata De Coco terus meningkat, produksi pada tahun 1994 adalah 390.000 kg (Departemen Perindustrian Bogor, 1995). Berdasarkan hal itu, pada penelitian ini dicoba "skim" santan sebagai bahan baku alternatif pembuatan nata de coco.
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Judul: Studi Kasus: Produk Nata De Coco PT. Halintar Bahana Prima Bogor, J;twa Bsrat
Abstrak: Nata de coco termasuk produk pangan olahan yang terbuat dari air kelapa. Pe~igolahan nata de coco dapat dilakukan oIeh perusallaan besar ataupun usaha kecil dan menet~gali karena teknologiuya yang tidak begitu rumit. Makana11 seperti nata de coco yaug praktis dan cepat penyajiannya diminati oleh penduduk 111do11esia. Maka jumlah perusahaan hdustri pengolahan sari kelapa nieningkat. Dampaknya adalah adanya persaingan yallg tajam dalam memperebutkan kons-.itnen dan mendapatkati ballan baku., ha1 ini nlel~yebabkan kotidisi pasar mel~jadi koinpetitif: Dilil~at dari ju~nlalp~e mbeli dan penjual yaiip, banyak serta berdagang dalam kisarau harga terterltu dan terdapat berbagai jenis produk yalig terdiferensiasi maka stmktur pasar nata de coco tennasuk persait~gan monopolistik
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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