Judul: Formulasi, Enkapsulasi Dan Karakterisasi Nanoemulsi Ekstrak Kurkuminoid Berbasis Medium Chain Triglycerides (Mct)
Abstrak: Kurkuminoid merupakan sub-kelompok senyawa fenolik pada rimpang famili Zingiberaceae yang terbukti memiliki banyak aktivitas farmakologis, tetapi bioavabilitasnya rendah. Tujuan dari penelitian ini yaitu membuat nanoemulsi sebagai sistem penghantaran ekstrak kurkuminoid dengan metode emulsion inversion point yang berbasis Medium Chain Triglycerides (MCT), memformulasikan kadar Tween 80 selaku pengemulsi sehingga diperoleh nanoemulsi terbaik berdasarkan ukuran partikel, Indeks Polidispersitas (IP) dan potensial zeta serta melakukan enkapsulasi terhadap nanoemulsi terbaik menggunakan maltodekstrin dengan metode spray dry. Berdasarkan hasil penelitian, formula A dengan kadar pengemulsi 50% memiliki ukuran partikel 234.2 nm, IP 0.2315 dan potensial zeta -37.9 dan dipilih sebagai formula terbaik untuk dienkapsulasi. Spray drying menghasilkan serbuk halus, tidak berbau dengan rendemen 47.19%. Serbuk enkapsulat memiliki karakteristik warna Yellow Red (YR) dengan nilai CIE L, a*, b* berturut-turut 67.33, +3.93, +73.94, kadar air 6.75%, aktivitas air (aw) 0.407 dan retensi minyak 88.6%. Morfologi permukaan kapsul berbentuk bulat seperti bola dengan permukaan yang halus dan ukuran bervariasi.
Keyword: enkapsulasi, kering hambur, kurkuminoid, MCT, nanoemulsi

Judul: Karakteristik Nanoemulsi Temulawak
Abstrak: Curcumin is the active compound that has many benefits for health, so the potential for development in the pharmaceutical. However, the development potential is limited by the natural characteristics of curcumin. Curcumin is known to have a low solubility in the gastrointestinal tract so it is relatively difficult to get into the blood plasma. In addition, curcumin also degraded easily by free radicals agent necessitating the addition of other antioxidants. One effort to overcome these problems is the manufacture nanokurkumin particles in the form of an emulsion (nanoemulsion). Nanoemulsion is made with high-speed homogenization method at 24 000 rpm for 40 minutes, in order to obtain a grain diameter of 32.62 ± 1.84 nm with a polydispersity index of 0255 ± 0013. Curcumin in preparation nanoemulsi have characteristics include bioavailability, solubility, and stability of droplet size. Nanoemulsion bioavailability test conducted by Franz diffusion method. Solvents used for the solubility test is hexane, water, ethanol, methanol, and acetone. Nanoemulsi droplet size stability tested by storage at 40C, room temperature and a temperature of 500C with a 90th day storage period. Curcumin in preparation nanoemulsi showed an increase absorption (bioavailability) of 45.97 % compared to the emulsion. In the solubility test changes the solubility of the preparations nanoemulsi than emulsion preparations in various solvents, suggesting a change in solubility characteristics. Nanoemulsi has the best solubility in ethanol with the percent dissolved at 96.74%. Nanoemulsi investigated have better stability than the emulsion preparation at various storage temperatures. Nanoemulsi ginger has better dimensional stability at 40C temperature storage with storage time of 60 days. The addition of citric acid (antioxidant) on nanoemulsi can inhibit decreased levels of curcumin.
Keyword: Bogor Agricultural University (IPB), stability., bioavailability, nanoemulsion, curcumin, Temulawak

Judul: Implementation of Spatio-Temporal Change Query in Relational Database.
Abstrak: Geographic object changes in various views. Object changes are recorded using a model of static storage. No historical connection between old version data and new version data has been built. For that, a storage model of spatio-temporal queries that can analyze spatio-temporal changes has been developed. The object changes the geometry are grouped according to the taxonomy of Spatio-Temporal Pattern Change. This research has been able to apply the query patterns change including born, expand, merge, contract, split, normal and die. This query based on geometric (area) changes. The implementation of spatio-temporal change queries represents an object changes continuously with easy, change detection is done by comparing two versions of data. Keyword: spatio-temporal change query, spatio-temporal change pattern.
Keyword: