Judul: Pengaruh Jenis Anyaman dan Perekat Terhadap Kualitas Sifat Fisis dan Mekanis Bambu Lapis dari Bambu Andong (Gigantochloa pseudoarundinaceae (Steudel)Widjaja))
Abstrak: This research aims to determine the effect of wove and adhesive type on the quality of woven bamboo plywood from andong with the use of dipping methods. Bamboo plywood bonded using MDI (Methylen Diphenyl Isocyanate) and PVAC (Polyvinyl Acetate). Woven bamboo was soaked in diluted adhesive. It was ensured that the adhesive spread equally on the bamboo’s surfaces (including inner bark strip and outer strip). Results show that in treatment, moisture content, modulus of elasticity (MOE), shrinkage and bonding strength did not have effect in improving the properties of bamboo plywood whereas in treatment density, modulus of rupture (MOR) and thickness swelling affected in improving the properties of bamboo plywood made from bamboo andong. The usage of PVAc did not improve physicals and mechanical properties of bamboo plywood, and did not meet ISO (SNI) 01-5008.2-2000 standard. The usage MDI did not improve bamboo plywood’s quality and its MOE and MOR did not meet the standard; moreover, its moisture content, density, and bonding strength did meet the the ISO (SNI) 01-5008.2-2000 standard
Keyword: woven bamboo., physicals and mechanical properties, PVAc, MDI, bamboo plywood

Judul: Karakteristik Bambu Lapis dari Anyaman Bambu Betung (Dendrocalamus asper) yang Direkat Menggunakan Perekat MDI dan PVAc dengan Metode Pencelupan
Abstrak: Plybamboo is an innovative product that should be improved strength and appearance to produce high quality products. The purpose of this research was to analyze the influence of adhesive type, and woven pattern toward the physical and mechanical characteristics of woven plybamboo. Water content, bonding strength, and MOR of plybamboo made using MDI adhesive is suitable with SNI 01-5008.2-2000 standard. Its water content value is under 14%, its bonding strength is more than 7 kg/cm2, and its MOR is more than 320 kg/cm2. Moreover, the water content, bonding strength, and MOR of woven bamboo made using PVAc did not suitable with SNI 01-5008.2-2000 standard. The density of plybamboo was ranged between 0.41-0.68 g/cm3. Based on shrinkage and swelling test of plybamboo, swelling phase was larger than shrinkage phase. The MOE of all samples did not suitable with SNI 01-5008.2-2000 standard. Plybamboo bonded using MDI with Tindih 2 pattern has better physical and mechanical characteristics than other plybamboos.
Keyword: PVAc, plybamboo, MDI, betung bamboo, bamboo woven

Judul: Prediction of T-Cell Epitope Candidate Targeting Conserved-KRAS for Cancer Vaccine using Reverse Vaccinology Approach
Abstrak: Kanker merupakan penyebab kematian kedua terbesar di dunia. Sebanyak 9.6 juta kematian manusia di dunia disebabkan oleh kanker. Kurang lebih sepertiga penderita kanker mengalami mutasi gen KRAS. Mutasi gen KRAS banyak terjadi pada kanker pankreas (90%), kanker kolon (30-40%), dan kanker paru (15-25%). Pendekatan reverse vaccinology dapat mempermudah pengembangan vaksin penyakit yang sebelumnya sulit dan tidak mungkin diproduksi. Penelitian ini bertujuan untuk merancang kandidat epitop sel-T dengan target conserved-KRAS sebagai imunoterapi kanker. KSFEDIHHY merupakan kandidat epitop terbaik yang dihasilkan dari rangkaian penelitian yang dilakukan. Kandidat epitop ini memiliki skor imunogenisitas yang baik, diprediksi dapat berikatan dengan banyak supertipe HLA, bersifat non-alergen dan non-toksik. KSFEDIHHY dapat berikatan dengan HLA B*57:01 dengan affinitas -7.8 kkal/mol. Prediksi ikatan antara peptida dan HLA yang telah dilakukan baik berdasarkan sekuens maupun berdasarkan struktur ini menunjukkan KSFEDIHHY potensial untuk dikembangkan sebagai kandidat epitop untuk vaksin kanker., Cancer is the second cause of death in the world. There are 9.6 million deaths caused by cancer. Approximately one third of cancer patients have the KRAS gene mutation. KRAS gene mutations occur mostly in pancreatic cancer (90%), colon cancer (30-40%), and lung cancer (15-25%). The reverse vaccinology approach can ease the difficulties and impossiblities to produce vaccine. This study aims to design T-cell epitopes candidate targeting the conserved-KRAS as cancer immunotherapy. KSFEDIHHY is the best epitope candidate from a series of assays conducted. This candidate epitope has a good immunogenicity score, predicted to be able to bind with many HLA supertypes, non-allergenic and non-toxic. KSFEDIHHY can make a complex with HLA B*57:01 with binding affinity -7.8 kcal/mol. Prediction analysis for both sequence-based and structure-based shows that KSFEDIHHY has the potential to be developed as an epitope candidate for cancer vaccines.
Keyword: reverse vaccinology, HLA class I, T-cell epitope