Judul: Evaluasi Penerapan Konsep Kota Hijau di Kota Bogor
Abstrak: Development of urban areas in Indonesia is very rapid. City is a reflection of local environment condition, citizen behavior and local culture. Activity and development of the city will cause of various environmental problems like the imbalance between urban growth and the improvement of environmental quality. It bring about the city become not liveable. Because of that is very important to create a comfortable city with safety guarantee and be the one with nature by applying the concept of green city. Green city is a concept of a healthy city, considering ecological aspects. This research use Gap Analysis to find out the actual condition of Bogor City and compare it with the ideal condition of green city concept and evalauate the implementation with scoring method. The results of this research showed that Bogor has had a city development plan towards sustainable city, but the implementations still have not been maximized. The implementations not been spread through the region and have not been solve the urban problems of Bogor City.
Keyword: urban landscape, green city, gap analysis

Judul: Evaluasi Penerapan Indeks Kinerja Lingkungan dan Konsep Kota Hijau di Kota Bogor.
Abstrak: Urbanisasi di Kota Bogor yang berkembang pesat berdampak pada penurunan kualitas lingkungan. Oleh karena itu diperlukan suatu konsep perencanaan kota yang berkelanjutan. Tujuan penelitian ini adalah membandingkan indeks kinerja lingkungan tentang konsep Kota Hijau di dunia dan mengevaluasi kinerja lingkungan Kota Bogor. Evaluasi kinerja lingkungan dilakukan dengan menggunakan 8 kategori dari Asian Green City Index yaitu Energi dan CO2, Penggunaan Lahan dan Bangunan, Transportasi, Sampah, Air, Sanitasi, Kualitas Udara dan Tata Kelola Lingkungan. Penelitian ini menggunakan metode kuantitatif dengan analisis deskriptif. Hasil yang didapatkan adalah rata-rata keseluruhan kinerja Kota Bogor dalam mewujudkan konsep Kota Hijau termasuk dalam nilai diatas rata-rata atau kategori baik (63.06%). Kinerja terendah adalah kategori energi dan CO2 (48.75%), penggunaan lahan dan bangunan (51.75%), kualitas udara (53.5%), sampah (58.5%) dan kinerja terbaik adalah kategori tata kelola lingkungan (88.11%).
Keyword: Asian Green City Index, pembangunan berkelanjutan, perubahan iklim, urbanisasi, tata kelola lingkungan

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
Keyword: