Judul: Aktivitas Antioksidan Nanokurkuminoid Varietas Temulawak Asal Balitro Pada Hati Tikus Jantan Sprague Dawley
Abstrak: Curcuma xanthorhiza Roxb. yang dikenal dengan nama temulawak adalah tanaman yang mengandung kurkuminoid dan memiliki sifat antioksidan. Karena bioavailabilitas kurkuminoid sangat rendah dalam tubuh sehingga diperlukan suatu penghantaran yang efisien ke dalam tubuh, seperti nanopartikel tersalut lemak padat. Tujuan penelitian ini adalah untuk mengukur aktivitas antioksidan hati tikus Sprague Dawley jantan secara in vivo dari nanokurkuminoid tersalut lemak padat keadaan stress oksidatif diinduksi CCl4. Analisis aktivitas antioksidan dilakukan dengan mengukur kadar Malondialdehida (MDA) dan aktivitas enzim Superoksida Dismutase (SOD), Glutation Peroksidase (GPx) dan Peroksidase (POX). Nanokurkuminoid yang diperoleh berukuran (114.4 ± 33.8) nm, dengan nilai indeks polidispersitas sebesar (0.233 ± 0.060). Efisiensi penjerapan kurkuminoid di dalam nanokurkuminoid yang didapatkan sebesar 70.96 ± 7.60 %. Hasil analisis pengukuran kadar MDA dan aktivitas enzim SOD, GPx dan POX menunjukkan bahwa nanokurkuminoid varietas temulawak asal balitro memiliki aktivitas antioksidan meskipun berdasarkan uji statistik diperoleh hasil yang tidak berbeda nyata (P>0.05) dengan kelompok normal.
Keyword: aktivitas enzim, antioksidan, hati tikus, in vivo, nanokurkuminoid.

Judul: Aktivitas Antioksidan Nanokurkuminoid Temulawak Lokal Ciemas Pada Tikus Sprague-Dawley Betina
Abstrak: Java turmeric (Curcuma xanthorrhiza) is a typical Indonesian plants that have antioxidant activity. Clinical testing showed that curcumin safe at high doses (12 g/day) but has low bioavailability. Delivery systems by making of solid lipid nanoparticles made to improve bioavailability of curcuminoids. This study aims to measure antioxidant activity of nanocurcuminoid coated solid lipid in female rat induced by CCl4. Analysis of antioxidant activity by measuring Malondialdehyde (MDA) levels and activity of superoxide dismutase (SOD), gluthatione peroxidase (GPX) and peroxidase (POX). Nanocurcuminoids size that obtained was 114.4±33.8 nm with polydispersity index 0.218 and adsorption efficiency 79%. The results showed that administration of nanokurkuminoid dose of 1500 mg/kg in female rats induced by CCl4 were able to reduce levels of MDA (4.34 nmol/mL) and increasing the activity of SOD (64.70 %), GPx (3208.02 mU/mL) and POX (3.13 mU/mL). These results indicate nanokurkuminoid have antioxidant activity.
Keyword: SLN., nanocurcuminoid, female sprague-dawley, CCl4, antioxidant

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
Keyword: