Judul: Kajian Toksikopatologi Pemberian Capsaicin Peroral terhadap Organ Lambung dan Usus Mencit C3H
Abstrak: Capsaicin is an active compound grouped in capsaicinoid in pepper plants. Capsaicin has many pharmacologic effect including cluster headcache therapy, postherpetic neuralgia, chronic pain, arthritis, diabeticneuropathic pain, and against a wide variety of tumor and cancer cells. The researcch was conducted to identify toxic effect of stomach and intestine that can be caused by capsaicin administered orally. Twelve mice straint C3H were divided into three groups: groups K1 (control), groups K2 (2 weeks treatment), and groups K3 (4 weeks treatment). Capsaicin was administered perorally for 2 weeks in K2 and 4 weeks in K3. The mice was necropsed, then the stomach and intestine were fixed in Buffer Neutral Formalin (BNF) for histopathological preparation. The results showed that capsaicin causes congestion, infiltration of inflammatory cell, and epithelium desquamation of the stomach and intestines. Based on these results, oral capsaicin is not safe for stomach and intestine.
Keyword: toxicopathology, stomach, C3H mice, capsaicin, Bogor Agricultural University (IPB)

Judul: Efektivitas Cabai Rawit (Capsicum annuum) terhadap  Efek Analgesik dan Stamina Mencit Jantan (Mus musculus)
Abstrak: Cayenne is used all over the world and is mostly used in cooking as a spice that is added to different dishes and sauces to give them flavour, colour, and perfume. Chilli peppers are a member of the genus Capsicum and has a compound found in chilli peppers that is active is called capsaicin (8-methyl-N-vanillyl-6 nonenamide). The term "fatigue" is frequently used and has multiple definitions, causal relationships, and domains. Capsaicin is a useful tool in the study of pain since it causes pain in addition to the feeling of heat. Mice's stamina can be increased by flavonoids through their inhibition of the phosphodiasterase enzyme, which is responsible for converting cAMP to AMP. This study determined the effectiveness of cayenne pepper (Capsicum annuum) on analgesic effect and stamina. The tail flick test was used to determine the analgesic effect of the treatment on mice. The swimming endurance test was used to determine the stamina of the mice. A total of 20 mice were used and divided into 4 treatment groups: control, 1, 2 and 4 mg/g BW. To determine the statistical significance of the data, ANOVA one-way and Tukey tests were conducted. Based on the statistical analysis, cayenne pepper was effective to increase stamina at 4 mg/g BW whereas cayenne pepper was effective to increase analgesic effect at 2 and 4 mg/g BW. In conclusion, cayenne pepper shows effects on both stamina and analgesic effect.
Keyword: analgesic effect, cayenne pepper, mice, stamina

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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