Judul: Transformasi Bogor menuju kota metropolitan (kasus transisi agraria masyarakat tepian kota, Kelurahan Mekarwangi, Kecamatan Tanah Sareal Bogor)
Abstrak: Transformasi pengembangan ruang merupakan sebuah konsekuensi dari adanya pembangunan daerah yang menjadi salah satu cara pemerintah (daerah) untuk meningkatkan kesejahteraan masyarakat. Namun pembangunan ini mengakibatkan terjadinya konversi lahan pertanian secara vertikal. Hal-hal yang mendorong terjadinya konversi lahan pertanian karena keterdesakan ekonomi. Faktor-faktor yang mendorong terjadinya konversi lahan pertanian menimbulkan transisi agraria yang ditunjukkan dengan pergeseran matapencaharian di bidang pertanian menjadi pekerja di sektor non-pertanian, pekerja di sektor campuran (pertanian dan non-pertanian), atau tetap bertahan bekerja di sektor pertanian sehingga mempengaruhi tingkat kesejahteraan masyarakat. Penelitian ini menguji pengaruh perubahan matapencaharian terhadap tingkat kesejahteraan. Hasil penelitian menunjukkan bahwa perubahan matapencaharian tidak memiliki pengaruh signifikan terhadap tingkat kesejahteraan. Hal ini disebabkan perubahan yang terjadi terlalu kecil sehingga terlihat tidak signifikan.
Keyword: area transformation, land conversion, livelihood, welfare

Judul: Konversi Lahan Pertanian dan Perubahan Taraf Hidup Rumahtangga Petani: Kasus Pembangunan Perumahan X di Kampung Cibeureum Sunting dan Kampung Pabuaran, Kelurahan Mulyaharja, Kecamatan Bogor Selatan, Kota Bogor, Provinsi Jawa Barat
Abstrak: Conversion of agricultural land and changes in household living standards of farmers: a case of Housing Development by PT. X in Kampung Cibeureum Sunting and Kampung Pabuaran, Kelurahan Mulyaharja, Kecamatan Bogor Selatan, Kota Bogor, West Java. The objectives of this study were: (1) identified household living standards of farmers after the land conversion, (2) analyzed the factors associated with land conversion rates by farmers. The research applied a quantitative approach which supported by qualitative information. The quantitative data were collected by using survey method on 35 farmers household . The results of this study showed that after the conversion of land, household living standard of farmers increased, especially for lower-class farmers households. Internal factors and external factors affect different for each of the farmers. In this study, the internal factors that affected the rate of land conversion is dependence on the land. Dependence of land only affect the conversion rate at the lower class farmers. External factors also have different effect on each among farmers. In this study, external factors which affected the conversion rate is the influence of neighborss, the influence of neighbors only affected the conversion rate at the lower-class farmers. Key words: Conversion, land, farmers
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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