Judul: Karakterisasi Morfologi, Anatomi, dan Kandungan Fitokimia Tanaman Handeuleum (Graptophyllum Pictum L. Griff)
Abstrak: Graptophyllum pictum L. Griff, called caricature plant is commonly used as medicinal plant. Caricature plant is indigenous plant as was reported to prosses that can function as uncer, laxative, and menstruation problem. However, there were very limited information about caricature plant accession with high biomass and high phytochemical content. Therefore exploration to habitat of caricature plant or their production site is needed to obtain caricature plant accessions with high biomass and high phytochemical content. The objective of this study was to explore the diversity of caricature plant accessions, morphology, anatomy, and phytochemicals caricature plant. This study also objected to analize and the similarity level of 32 caricature plant accesions, and study the agroecological correlation with morphology, anatomy, and phytochemicals contents of those accessions. The research was conducted in Indonesian Medicinal and Aromatics Crop Research Institute (IMACRI) Cimanggu Bogor. The study was started in June 2008 until September 2009. Plant material use in this study was stem cutting of caricature plant from various locations which previous explorased by KKP3T research team, include West Java, Central Java, East Java, Central Kalimantan, South Kalimantan, Ambon, Papua, and IMACRI collections. This experiment was arranged in completely randomized design with single factor (32 caricature plant accessions based on area of origin) and two replications. One replication consisted of 10 plants. The results showed caricature plants fom different location have similarity with plant morphology include sectional stem cross shape, the surface of the stem, branching, leaf base shape, nervatio, and leaf abaxial surface. The diversity of plant morphology shape of leaves and leaf edges. Leaf anatomy analysis result showed that leaf thickness was similar between handeuleum accessions originated from various locations. In contrast, there was variation in the stomatal density of handeuleum accessions. Phytochemical analysis of caricature plant leaves showed that all of the caricature plant accessions have high alkaloids and glycosides content. There were variations in saponin, tanin, phenolic, flavonoids, triterpenoids, steroid content of caricature plant accessions.
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Judul: Chemometric Analysis of Plant Origin and Polarity Index on Total Phenolics, Flavonoids, and Antioxidant Activity of Caricature Plant (Graptophyllum pictum (L.) Griff.) Extract
Abstrak: Daun ungu (Graptophyllum pictum (L.) Griff.) adalah tumbuhan obat dari Papua Nugini dan Polinesia yang kemudian menyebar ke Indonesia. Asal tanaman, indeks polaritas pelarut, serta total fenolik dan flavonoid diduga memiliki korelasi terhadap aktivitas antioksidan daun ungu. Penelitian dilakukan bertujuan untuk mengetahui besarnya pengaruh asal tanaman, indeks polaritas pelarut, serta total fenolik dan flavonoid terhadap aktivitas antioksidan (DPPH) daun ungu menggunakan analisis PCA. Korelasi rendemen ekstrak daun ungu menghasilkan nilai korelasi Pearson sebesar 0.857 dan nilai p sebesar 0.063 serta nilai korelasi Spearman sebesar 0.872 dan nilai p sebesar 0.054. Dalam komparasi kandungan fitokimia daun ungu, sampel daun ungu asal Thailand tidak memiliki kandungan alkaloid dan glikosida. Berdasarkan kandungan fenolik, flavonoid, dan aktivitas antioksidannya, sampel daun ungu asal Indonesia dan Thailand terbagi menjadi dua jenis yang berbeda., Caricature Plant (Graptophyllum pictum (L.) Griff.) is a medicinal plant from Papua New Guinea and Polynesia which later spread to Indonesia. Plant origin, solvent polarity index, and total phenolics and flavonoids are thought to have a correlation to the antioxidant activity of purple leaves. The aim of this study was to determine the effect of plant origin, solvent polarity index, and total phenolic and flavonoid on the antioxidant activity (DPPH) of caricature plant using PCA analysis. The yield correlation of purple leaf extract resulted in a Pearson correlation value of 0.857 and a p-value of 0.063 and a Spearman correlation value of 0.872 and a p-value of 0.054. In comparison to the phytochemical content of caricature plants, caricature plant samples from Thailand did not contain alkaloids and glycosides. Based on the phenolic content, flavonoids, and antioxidant activity, caricature plant samples from Indonesia and Thailand were divided into two different types.
Keyword: Antioxidant, Flavonoid, Graptophyllum pictum, phenolic, origin, polarity index

Judul: A Continuous Vaccination Strategy in the SVIR Epidemic Model
Abstrak: Vaccination is conducted to minimize the spread of a disease. The vaccination is usually done several times within a fixed time interval. In the SVIR model, it is assumed that individuals do not get immediate immunity following a vaccination program. So according to process of vaccination on SVIR model, there are two strategies, i.e. the continuous vaccination strategy (CVS) and the pulse vaccination strategy (PVS). In this study, only the CVS strategy in epidemic model SVIR is considered. Results of the study indicate that dynamics of the CVS system depends on the basic reproductive number. If the basic reproductive number is less than one, then the disease-free fixed point is asymptotically stable. It means that the disease will eventually disappear from the population. Conversely, if the basic reproductive number is greater than one, then the endemic fixed point is asymptotically stable, which means that the disease will remain exist in the population. Simulation result shows that the vaccination would minimize the spread of disease by reducing the basic reproductive number. If the time for the vaccinated recipients to obtain the immunity, as well as a possibility of vaccinated recipients to be infected are neglected, then the disease will be eradicated. This condition is called an over-evaluating effect of vaccination.
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