Judul: Peranan Pemimpin Informal dalam Keberlanjutan Kelompok  (Kasus : Gapoktan Ternak Domba Mekar Jaya, Desa Kadipaten,  Kecamatan Kadipaten, Kabupaten Majalengka, Propinsi Jawa  Barat)
Abstrak: This research take the theme about the role of Informal Leaders in Sustainability process of farmers group. The group here is Farmers sheep groups united that called Mekar Jaya. The frame of this research think that the sustainabilty of Farmers group is influenced by several factors. Those are internal factors of group, The role of informal leaders, afld external factors of group. This research also want to see about The rank or stage of sustainability of group itself. The sample of research is about 79 peoples who is the members of group. The data was collected by using quitiinary and depth interview. The survei has conducted since March until April 2002. Finnaly, the data was analyzed by using Tau-kendall technique to explain correlation among sustainability of group with the factors that can influence it. Sosiometry technique is also using to find the cliques and the leaders in group. The analysis is completed by explaining the development stage of group with planned change method.
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Judul: The Relationship between the Role of Informal Leaders and the Formation of Social Capital in The Community (Case : Thematic Village, Agroedutourism Ciharashas, South Bogor, West Java)
Abstrak: Hadirnya seorang pemimpin pastinya diharapkan dapat menjadi seorang yang dapat mendorong masyarakat kearah yang lebih sejahtera. Peran pemimpin dapat dianalisis dari 3 kelompok yakni peran pemimpin secara motivator, Fasilitator, dan Mobilisator. Jika pemimpin telah mampu menjalankan ketiga peran pemimpin tersebut, diharapakan modal sosial juga terbentuk pada masyarakat, bentuk modal sosial yang terbentuk yakni bonding, briding dan linking. Penelitian ini mengkaji mengenai hubungan peran pemimpin informal, dengan terbentuknya modal sosial yang ada di masyarakat dengan menggunakan metode pendekatan kuantitatif dan kualitatif atau biasa disebut mix method. Pada metode pendekatan kuantitatif menggunakan wawancara terstruktur, sedangkan pada penelitian kualitatif menggunakan wawancara mendalam. Sampel penelitian dipilih dengan metode sensus, sementara informan dipilih berdasarkan pengalaman dan pengetahuan terkait peran pemimpin yang ada secara purposive sampling. Hasil penelitian menunjukkan bahwa tidak ada hubungan antara peran pemimpin informal dengan terbentuknya modal sosial yang ada di masyarakat. Secara kualitatif diketahui bahwa modal sosial terbentuk karena adanya beberapa faktor yakni : lingkungan yang homogen, ketergantungan ekonomi, kebutuhan ekonomi, tradisi dan budaya yang ada, kebutuhan bersama, partisipasi, serta keuntungan yang diperoleh., The presence of a leader is certainly expected to be someone who can push society towards a more prosperous direction. The role of the leader can be analyzed from 3 groups, namely the role of the leader as a motivator, facilitator and mobilizer. If the leader has been able to carry out the three leadership roles, it is hoped that social capital will also be formed in the community, the forms of social capital that are formed are bonding, briding and linking. This research will examine the relationship between the role of informal leaders and the formation of social capital in society by using quantitative and qualitative approaches or commonly called the mix method. The quantitative approach uses structured interviews, while the qualitative research uses in-depth interviews. The research sample will be selected using the census method, while the informants will be selected based on experience and knowledge regarding the role of existing leaders by purposive sampling. The research results show that there is no relationship between the role of informal leaders and the formation of social capital in society. Qualitatively, it is known that social capital is formed due to several factors, namely: a homogeneous environment, economic dependence, economic needs, existing traditions and culture, shared needs, participation, and profits obtained.
Keyword: Community, Kampung Tematik, Leader role, Social capital

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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