Judul: The potency of mahogany bark as a lower of blood cholesterol hipercholesterolemia white rats.
Abstrak: Salah satu tumbuhan yang diyakini berkhasiat sebagai tumbuhan obat untuk menurunkan kolesterol darah adalah mahoni (Swietenia macrophylla King.). Penelitian ini bertujuan menguji khasiat ekstrak kulit kayu mahoni sebagai penurun hiperkolesterolemia secara in vivo pada tikus galur Sprague Dawley. Sebanyak 25 ekor tikus jantan dibagi menjadi 5 kelompok (n=5), yaitu kelompok normal (N) diberi pakan standar, kelompok hiperkolesterolemia (HK) diberi pakan kolesterol (1.5%) dan propil tiourasil (PTU) (0.5mg/KgBB), kelompok lovastatin (HK+lovastatin 0.2875 mg/kgBB), kelompok perlakuan ekstrak 1/ E1 (HK+ekstrak air mahoni 150 mg/kgBB), serta kelompok perlakuan ekstrak 2/ E2 (HK+ekstrak air mahoni 300 mg/KgBB). Masa percobaan berlangsung selama 7 minggu, dibagi menjadi 2 periode yaitu peningkatan kolesterol selama 6 minggu dan perlakuan ekstrak kulit kayu mahoni selama 1 minggu. Konsentrasi kolesterol total darah dianalisis setiap 2 minggu dengan metode enzimatik kolesterol oksidase CHOD-PAP (cholesterol oxidase phenol amino phenanzone ) yang diukur dengan spektrofotometer pada panjang gelombang 505 nm. Hasil penelitian menunjukkan pemberian pakan kolesterol (1.5%) dan PTU (0.5 mg/kgBB) selama 7 minggu pada kelompok HK mampu menaikkan konsentrasi kolesterol sebesar 245.50%. Analisis statistik mendukung bahwa kelompok E2 signifikan terhadap kelompok HK dan tidak signifikan terhadap kelompok normal. Sementara dosis ekstrak 150 mg/kgBB tidak berbeda nyata dengan HK. Berdasarkan data dapat disimpulkan bahwa kelompok E2 mampu menurunkan konsentrasi kolesterol.
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Judul: Khasiat Ekstrak Kulit Kayu Mahoni (Swietenia macrophylla King.) sebagai Pencegah Hiperkolesterolemia pada Tikus Putih
Abstrak: Mahoni’s bark has been thought as wood industrial waste, it’s potency as hypercholesterolemic prevention agent has not been reported. The aim of this study was to test the potency of mahoni’s bark extract as hypercholesterolemic prevention agent in rats. Thirty five male rats were divided into 5 groups (n=7) namely normal group (N) fed with standard rat chow, hypercholesterolemic group (HK) fed with cholesterol chow (1,5%) and PTU (0,5 mg/KgBW), lovastatin group (HK + lovastatin 0,2857 mg/KgBW), E1 group (HK+ mahoni’s water extract 4,2 mg/KgBW), and E2 group (HK + mahoni’s water extract 21mg/KgBW). Experiments were carried out for 8 consecutive weeks. The total blood cholesterol concentrations were analyzed every 2 weeks using enzymatic cholesterol oxidase methode CHOD-PAP and measured by spectrophotometer at =500 nm. The results showed that administration of cholesterol chow (0,86%) and PTU (0,5 mg/KgBW) for 8 weeks in HK group increased cholesterol concentration 52,57%. Although the data statistically was not significant ( = 0.05), there is a tendency that mahoni’s extract at the dose E2 cause 35,8% reduction of cholesterol concentration and this was comparable to the reduction in the lovastatin group (33,78%).
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Judul: Implementation of Spatio-Temporal Change Query in Relational Database.
Abstrak: Geographic object changes in various views. Object changes are recorded using a model of static storage. No historical connection between old version data and new version data has been built. For that, a storage model of spatio-temporal queries that can analyze spatio-temporal changes has been developed. The object changes the geometry are grouped according to the taxonomy of Spatio-Temporal Pattern Change. This research has been able to apply the query patterns change including born, expand, merge, contract, split, normal and die. This query based on geometric (area) changes. The implementation of spatio-temporal change queries represents an object changes continuously with easy, change detection is done by comparing two versions of data. Keyword: spatio-temporal change query, spatio-temporal change pattern.
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