Judul: Pengaruh komunikasi pemasaran obyek wisata terhadap perilaku wisatawan: studi kasus obyek wisata alam Gunung Galunggung, Desa Linggajati, Kecamatan Sukaratu, Kabupaten Tasikmalaya, Propinsi Jawa Barat
Abstrak: This study focused on the influence of marking communication on tourist behavior (Case: Object nature tourism mMountain Galunggung, Linggajati Village, District Sukaratu, Tasikmalaya regency). The purpose of this study is to determine: (1) the extent to affect perceptions of marking communication messages and (2) the extent of perceptions of message affect tourist behavior.
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Judul: Efektivitas bauran komunikasi pemasaran Taman Wisata Alam Pananjung, Kecamatan Pangandaran, Kabupaten Pangandaran, Jawa Barat
Abstrak: Keberhasilan ekowisata di suatu daerah yang dikelola langsung oleh pemerintah daerah sangat bergantung pada seberapa besar dan gencarnya kegiatan komunikasi pemasaran yang dilakukan oleh pemerintah daerah dan pihak-pihak terkait. Komunikasi pemasaran yang efektif adalah aspek penting dalam keseluruhan misi pemasaran serta penentu suksesnya pemasaran. Tujuan yang ingin dicapai dalam penelitian ini adalah mendeskripsikan bentuk bauran komunikasi pemasaran, menganalisis efektivitas bauran komunikasi pemasaran pada aspek kognitif, afektif, dan konatif, menganalisis hubungan antara karakteristik pengunjung dan keterdedahan bauran komunikasi pemasaran dengan efektivitas komunikasi pemasaran pada aspek kognitif, afektif, dan konatif. Metode penelitian yang digunakan ialah penelitian kuantitatif yang didukung dengan data kualitatif. Hasil penelitian menunjukkan bahwa terdapat hubungan signifikan antara karakteristik pengunjung pada variabel usia dengan efektivitas bauran komunikasi pemasaran pada aspek afektif dan karakteristik pengunjung pada variabel tingkat pendapatan dengan efektivitas bauran komunikasi pemasaran pada aspek afektif dan konatif. Kata kunci:
Keyword: bauran komunikasi pemasaran, efektivitas, ekowisata

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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