Judul: Khasiat Ekstrak Kulit Kayu Mahoni (Swietenia macrophylla King.) sebagai Pencegah Hiperkolesterolemia pada Tikus Putih
Abstrak: Mahoni’s bark has been thought as wood industrial waste, it’s potency as hypercholesterolemic prevention agent has not been reported. The aim of this study was to test the potency of mahoni’s bark extract as hypercholesterolemic prevention agent in rats. Thirty five male rats were divided into 5 groups (n=7) namely normal group (N) fed with standard rat chow, hypercholesterolemic group (HK) fed with cholesterol chow (1,5%) and PTU (0,5 mg/KgBW), lovastatin group (HK + lovastatin 0,2857 mg/KgBW), E1 group (HK+ mahoni’s water extract 4,2 mg/KgBW), and E2 group (HK + mahoni’s water extract 21mg/KgBW). Experiments were carried out for 8 consecutive weeks. The total blood cholesterol concentrations were analyzed every 2 weeks using enzymatic cholesterol oxidase methode CHOD-PAP and measured by spectrophotometer at =500 nm. The results showed that administration of cholesterol chow (0,86%) and PTU (0,5 mg/KgBW) for 8 weeks in HK group increased cholesterol concentration 52,57%. Although the data statistically was not significant ( = 0.05), there is a tendency that mahoni’s extract at the dose E2 cause 35,8% reduction of cholesterol concentration and this was comparable to the reduction in the lovastatin group (33,78%).
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Judul: Peroksidasi Lipid pada Tikus Hiperkolesterolemia selama Pemberian Ekstrak Kulit Batang Mahoni (Swietenia macrophylla)
Abstrak: Mahogany’s bark is known as wood industrial waste that contains potential secondary metabolites. However, its potency as an antioxidant, especially in rats which are subjected to hypercholesterolemic treatment, has not been carried out. The aim of this study was to test the effect of mahogany’s water extract consumption on the concentration of lipid peroxides in hypercholesterolemic rats. Thirty five male rats were divided into 5 groups (n=7) namely normal group fed with standard rat chow, hypercholesterolemic group (HK) fed with cholesterol chow (1,5%) and PTU (0,5 mg/KgBW), lovastatin group (HK+lovastatin 0,2857 mg/KgBW), E1 group (HK+ mahogany’s extract 4,2 mg/KgBW), and E2 group (HK+mahogany’s extract 21 mg/KgBW). Experiments were carried out for 8 consecutive weeks. The concentration of lipid peroxides in blood were measured with thiobarbituric acid assay at week 0, 2, 4, 6, and 8 using spectrophotometer. Cholesterol chow (0.86%) and PTU increased the lipid peroxides concentration of HK group by 20.92% compared to the normal group (3.380±0.436 nmol/mL). However, it is not statistically significant (p=0.239). The lipid peroxides concentration in E1 and E2 weren’t increased and relatively similar to normal group at concentration of 2.353±0.196 nmol/mL, 2.786±0.256 nmol/mL, and 2.673±0.279 nmol/mL, respectively. Although it is not statistically significant, both doses of extracts tend to prevent the lipid peroxidation in the rat’s blood.
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Judul: Identifikasi Kejadian Banjir Rob (Pasang) di DAS Sunter pada 9-13 Januari 2008.
Abstrak: Banjir Rob merupakan fenomena meluapnya air laut ke daratan, istilah tersebut pertama kali dikenal di daerah Semarang. Fenomena banjir Rob dipengaruhi oleh pasang surut air laut. Pasang surut sendiri dipengaruhi gravitasi bulan dan matahari, serta dipengaruhi pula posisi bulan dan matahari terhadap bumi. Banjir ini biasa terjadi pada saat pasang air laut yaitu bertepatan dengan kejadian bulan baru dan bulan purnama. Pada bulan Januari 2008, di wilayah utara Jakarta yang berbatasan dengan laut, fenomena banjir Rob (pasang) melanda kawasan tersebut. Fenomena ini mengakibatkan sejumlah kawasan di wilayah utara Jakarta terendam air laut, hal ini diperburuk dengan penurunan muka tanah Jakarta. Selain dilanda banjir pasang air laut, kawasan utara Jakarta sering dilanda banjir akibat luapan sungai-sungai yang bermuara di Jakarta, salah satu sungai yang menyumbang banjir Jakarta adalah sungai Sunter. Tutupan lahan di DAS Sunter yang sebagian besar berupa pemukiman makin meningkatkan limpasan permukaan ketika terjadi hujan. Tanggal 9-13 Januari 2008 di perairan Teluk Jakarta sedang terjadi pasang air laut karena bertepatan dengan bulan baru yang mengakibatkan terjadinya banjir Rob di beberapa wilayah di Jakarta Utara, termasuk DAS Sunter. Berdasarkan pemetaan banjir Rob di DAS Sunter pada tanggal 9-13 Januari 2008 diketahui bahwa daerah yang tergenang air laut yaitu Kalibaru dan Marunda dengan tinggi genangan 48-72 cm. Luas genangan maksimum terjadi pada tanggal 11 Januari 2008 yaitu sebesar 66.000 m2. Pada tanggal 9-13 Januari, DAS Sunter tidak ikut menyumbangkan limpasan permukaan yang dapat menyebabkan banjir karena nilai limpasan permukaan berkisar 0-3,03 mm. Sehingga kejadian banjir pada tanggal 9-13 Januari 2008 di DAS Sunter hanya berasal dari pasang air laut. Kata Kunci : Banjir Rob, Pasang-Surut, Limpasan Permukaan, DAS Sunter.
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