Judul: Kajian Laju Deforestasi dan Degradasi Hutan Di Kabupaten Lamandau dan Kotawaringin Barat Provinsi Kalimantan Tengah
Abstrak: Issue of deforestation and forest degradation has been attracting the international and national community’s attention. This study was performed to identify rate and driving force of deforestation and degradation occurred in Lamandau and Kotawaringin Barat, Central Kalimantan Province. The study objective is to identify the rate and driving forces of deforestation as well as forest degradation using medium resolution image, Landsat TM. The classification method used to detect and analyze deforestation and forest degradation was visual interpretation, then followed by thematic change technique. Identification of deforestation and forest degradation driving force was done using a depth interview. The results of study show that the deforestation rate during the period of 1990-2013 is 56 408.3 ha/year, while forest degradation rate is 36 195.0 ha/year. The main driving forces of deforestation and forest degradation are opening up forest for road constructions, settlement establishment, estate crop and agriculture development. The major agents of deforestation and forest degradation are local community contributing of approximately 10%, while the rest was contributed by estate crop company (palm oil company).
Keyword: visual interpretation, thematic change, driving force, forest degradation, deforestation, Bogor Agricultural University (IPB)

Judul: Lintasan dan Model Spasial Deforestasi di Kalimantan Periode 2000-2013
Abstrak: Carbon emissions in Indonesia was contributed by the forestry sector. Yet, forest absorbs carbon emissions by photosynthesis processes and stores it in the forest biomass. This conditions causes the forestry sector could played a main role in the efforts to reduce global warming. Emission in forestry sector is mainly caused by deforestation for various purposes. Sustainable forest management approaches as important mechanisms to ensure balance in the use of forest resources for humans and the environment. Kalimantan island has large forest cover and has high rate deforestation. The trajectory and spatial model of deforestation was expected to provide more detailed information about the phenomenon of deforestation in Kalimantan that could be organized on sustainable forest management planning. This study used time-series land cover data from Ministry of Forestry in 2000–2013 and validated with SPOT 5/6 images in 2013. land cover data was used to analyzed the trajectory and spatial model of deforestation. The spatial model of deforestation were developed using logistic regression with data in 2000–2006 and then implemented in 2006–2013. The variables that used to predicted influence on the models were slope, altitude, peatlands, distance from forest edge, distance from plantations edge, distance from road, distance from river, farmer households, human population and Gross Regional Domestic Product (GDRP). Trajectory analysis of deforestation in Kalimantan in the period 2000-2013 suggests that a deforested has not been optimally exploited because most of land cover were still in the form of shrubs until the end of the period. The results of logistic regression analysis that obtained spatial model of deforestation in Kalimantan Pi = 1.1480714 - (0.033262*slope) - (0.002242*elevation) - (0.000413*distance from forest edge) + (0.000045*GDRP). The result of validation test of deforestation model in 2000–2006 has a value of overall accuracy about 79.64% and model of deforestation in 2006–2013 has value of overall accuracy about 77.01%.
Keyword: trajectory, spatial model, logistic regression, deforestation, Kalimantan

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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