Judul: Identifikasi Pengaruh Variabilitas Iklim Di Kota Bogor Terhadap Adaptasi dan Pengeluaran Masyarakat
Abstrak: Indonesian territory south of the equator is now going on a longer dry season and the rainy season is shorter but with a higher rainfall. It also occurs in Bogor on climate indicator of temperature, rainfall, number of rainy days, and the number of days without rain. Climate variability is expected to impact the adaptation strategies and household expenditure indirectly. This study aims to analyzed the public perception about climate change, analyze the community adaptation to face the climate change, analyzed the impact of climate change on household expenditure, and identified factors that affect the community in adapting to climate changes. This study used a descriptive method and multiple linear regression analysis. The results of this study is that the adaptation of temperature increased on low-income, medium-income, and high-income community through roof improvement amount of 6%, 14%, and 36%, and used the fan amount of 38%, 70%, dan 62%. In adaptation from changed the rainfall and rainy days through roof fixing amount of 48%, 66%, and 66%, and used umbrella amount of 76%, 74%, and 86%. Increasing temperature affected on household expenditure for adaptation through home improvement or addition and the use of household goods amount of Rp 2 433 070, Rp 7 038 930, Rp 20 580 640 and household expenditure by climate change with changing the rainfall and rainy days amount of Rp 4 588 290, Rp 20 383 370, Rp 49 758 430 .
Keyword: Bogor Agricultural University (IPB), household expenditure, adaptation, public perseption, climate variability

Judul: Impact of Climate Variability on Adaptation Strategies and Rice Farming Income (Case Study: Katulampa Village, Bogor City)
Abstrak: Variabilitas iklim yang terjadi di Katulampa berupa intensitas curah hujan yang tinggi, perubahan pola curah hujan dan serangan organisme pengganggu tanaman dapat menjadi ancaman bagi petani padi karena dapat berimbas pada pendapatan usahatani padi. Dampak variabilitas iklim yang besar memerlukan upaya strategi adaptasi. Penelitian ini bertujuan: (1) menganalisis persepsi petani terhadap variabilitas iklim; (2) mengestimasi perubahan pendapatan petani padi akibat variabilitas iklim; (3) mengidentifikasi strategi adaptasi yang dilakukan oleh petani dalam menghadapi variabilitas iklim; dan (4) menganalisis faktor-faktor yang memengaruhi biaya adaptasi petani. Penelitian ini menggunakan analisis deskriptif, skala Likert, analisis pendapatan usahatani dan metode regresi linier berganda. Hasil penelitian menunjukkan bahwa persepsi petani padi terhadap variabilitas iklim dan kerugian ekonomi cukup beragam. Variabilitas iklim menyebabkan perubahan rata-rata produktivitas dengan selisih sebesar 34%. Rata rata biaya adaptasi terbesar dilakukan oleh kelompok luas lahan >0,6 Ha. Faktor faktor yang memengaruhi biaya adaptasi yaitu variabel luas lahan dan variabel lama bertani, The climate variability that occurs in Katulampa, particularly high rainfall intensity, rainfall pattern change and attack of plant pests, will threaten rice farmers in terms of affecting rice farmers’ income. Therefore, impact of climate variability requires adaptation strategies. The objectives of this research are to: (1) analyze farmers perceptions of climate variability, (2) estimate changes in rice farmersincome due to climate variability (3) identify forms of adaptation strategies carried out by farmers in dealing with climate variability, (4) analyze factors that affect adaptation costs farmer. This research uses descriptive analysis, Likert scale, farm income analysis and multiple linear regression methods. The results showed that rice farmers perceptions of climate variability and economic losses were quite diverse. Climate variability causes a decrease in average productivity of 34%. The largest average adaptation cost was carried out by the land area group > 0.6, namely the cost of adaptation is carried out by the land area group > 0,6. Factors that affect adaptation costs are land area and duration of farming.
Keyword: analisis pendapatan, curah hujan, Katulampa, persepsi, regresi linier berganda, income analysis, Katulampa, multiple linear regression, perception, rainfall

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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