Judul: Potensi Antikanker Royal Jelly Apis mellifera terhadap Sel WiDr ATCC®-CCL™ 218 dan Sel HeLa ATCC®-CCL-2™
Abstrak: Kanker serviks merupakan kanker penyebab kematian wanita kedua terbesar setelah kanker payudara di Indonesia, sedangkan kanker kolon merupakan kanker penyebab kematian pertama di dunia setelah penyakit jantung koroner. Salah satu upaya pengobatan kanker yang dapat dilakukan adalah mengkonsumsi bahan yang berpotensi sebagai antikanker, salah satunya adalah royal jelly Apis mellifera. Berdasarkan penelitian sebelumnya, royal jelly mampu menginhibisi sel kanker payudara MCF-7 1 mg/mL dan sel kanker kolon CaCo-2 0.5 mg/mL. Tujuan dari penelitian ini adalah menguji aktivitas sitotoksik royal jelly Apis mellifera terhadap sel kanker serviks (HeLa) dan sel kanker kolon (WiDr) dan sel hati (Chang) secara in vitro. Hasil uji antikanker menunjukkan potensi antikanker royal jelly lebih baik terhadap sel HeLa dibandingkan sel WiDr. Aktivitas royal jelly terhadap sel normal Chang mampu meningkatkan pertumbuhan sel sebesar 42.30% ± 13.01. Royal jelly mampu menghambat 36.42% ± 7.90 pertumbuhan sel HeLa, sedangkan terhadap sel WiDr hanya menghambat 16.65% ± 4.80 pada konsentrasi 125 g/mL.
Keyword: kanker kolon, kanker serviks, MTT, royal jelly

Judul: Cytotoxicity Test and Colon Anticancer Activity of the Monoflora Honey of Bees (Apis Mellifera) with Variations of Nectar Sources
Abstrak: Kanker kolon merupakan kanker dengan jumlah kasus dan jumlah kematian terbanyak di dunia. Madu monoflora dari Apis mellifera merupakan salah satu bahan alam yang berpotensi sebagai antikanker kolon dan memerlukan kajian lebih lanjut karena efektivitasnya dipengaruhi oleh perbedaan jenis sumber nektar. Penelitian ini bertujuan menentukan jenis madu monoflora Apis mellifera yang sumber nektarnya berasal dari tanaman-tanaman di Indonesia sebagai antikanker kolon terbaik berdasarkan nilai LC50 dan persentase inhibisi terhadap sel WiDr. Madu diuji dengan metode BSLT dan MTT assay kemudian data dianalisis secara statistik serta dilakukan PCA dan klasterisasi K-means. Hasil penelitian menunjukkan seluruh madu berpotensi sebagai antikanker kolon. Analisis biplot pada PCA dan klasterisasi K-means menunjukkan madu dengan potensi antikanker kolon terbaik adalah madu akasia, madu mangga, dan madu kapuk randu. Ketiga madu tersebut memiliki nilai LC50 rendah dengan metode BSLT, yaitu masing-masing sebesar 153,816 ppm, 164,207 ppm, dan 170,053 ppm. Ketiga madu tersebut memiliki persentase penghambatan yang besar terhadap sel kanker WiDR, yaitu masing-masing sebesar 72,42%, 74,31%, dan 63,96%., Colon cancer is a cancer with the highest number of cases and deaths in the world. Monoflora honey from Apis mellifera is one of the natural ingredients that has the potential as an anticancer colon and requires further study because its effectiveness is influenced by different types of nectar sources. This study aims to determine the type of Apis mellifera monoflora honey which sources its nectar from plants in Indonesia as the best colon anticancer based on the LC50 value and the percentage of inhibition against WiDr cells. Honey was tested using the BSLT and MTT assay methods, then the data was analyzed statistically and PCA and K-means clustering were carried out. The results showed that all honey has the potential as an anticancer colon. Biplot analysis on PCA and K-means clustering showed that the honey with the best colon anticancer potential was acacia honey, mango honey, and kapok honey. The three honeys had low LC50 values using the BSLT method, namely 153,816 ppm, 164,207 ppm and 170,053 ppm respectively. The three honeys had a large percentage of inhibition against WiDR cancer cells, namely 72,42%, 74,31% and 63,96%, respectively.
Keyword: cytotoxicity, antiproliferation, honey, nectar, clustering

Judul: Utilization of terra/MODIS L1B data for analysis of horizontal wind profile in the troposphere
Abstrak: This study was concerned with horizontal wind derived from data collected with the Moderate-resolution Imaging Spectroradiometer (MODIS) on board the NASA’s Earth Observation System (EOS)-Terra satellite. The aim of this study is to develop a method for the estimation of horizontal wind movement in the troposphere based on Navier-Stokes equation. The method was applied to a calibrated and geolocated Terra/MODIS L1B 1 km data set. The data inputs to estimate surface temperature are retrieved from TIR (Thermal Infrared) bands 31 (10.780 μm to 11.280 μm) and 32 (11.770 μm to 12.270 μm). The obtained surface temperatures were later used to approximate geopotential height on a constant-pressure surface by using the modified Poisson equation. The main assumptions used are the hydrostatic equilibrium, ideal gas law, constant lapse rate and constant acceleration of gravity. Based on the distribution of geopotential height, the pressure gradient force is measured by the gradient of geopotential on an isobaric coordinate to present the horizontal wind profile. For certain topographic areas especially in the mountain ranges, there was a disadvantage of using pressure as a vertical coordinate which lead to inaccuracy. In spite of that, Terra/MODIS L1B data with 1 km spatial resolution can be used to estimate the horizontal wind movement in the troposphere.
Keyword: