Judul: Sitotoksisitas dan Toksisitas Daun Miana (Coleus scutellarioides [L] Benth)
Abstrak: Daun miana (Coleus scutellarioides [L] Benth) telah digunakan masyarakat secara tradisional dalam mengobati beberapa penyakit. Penelitian ini bertujuan menentukan nilai LC50, toksisitas akut, mengetahui gejala toksik, dan wujud toksik dengan pengamatan histopatologi pada organ hati. Uji sitotoksisitas menggunakan larva udang (metode BSLT) dan uji toksisitas akut menggunakan mencit betina (metode OECD dan kriteria GHS). Berdasarkan hasil penelitian, nilai LC50 ekstrak aseton daun miana adalah 787.93 µg/mL. Toksisitas akut ekstrak aseton daun miana termasuk kategori 4 (>2000-5000 mg/kgBB) atau dalam kategori toksisitas rendah. Ekstrak aseton daun miana tidak menimbulkan kematian maupun gejala toksik yang tidak dapat ditoleransi hingga hari ke-14 setelah pemajanan. Pengamatan histopatologi menunjukkan terbentuknya lesi di beberapa sampel organ hati berupa degenerasi sentrolobular dan nekrosis.
Keyword: Coleus scutellarioides, Histopathology, LC50, Acute Toxicity, OECD 423, Histopatologi, Aktivitas sitotoksisitas, Potensi toksisitas akut, Gejala toksik

Judul: Isolasi dan Karakterisasi Senyawa Antibakteri Ekstra Daun Miana (Coleus scuatellariodes [L] Benth)
Abstrak: Miana is Lamianceae. It is commonly used as traditional medicine for infection and inflamation, cause by bacterial. The aim of this study to isolate and characterize ofantibacterial compound from miana leave extract. It is expected that the result will give information on characteristics and minimum inhibition concentration (MIC) of miana leave extract which have the highest antibacterial activity. The method of this research were extraction by Harborne method, antibacterial activity test by agar well diffution to staphylococcus aureus, staphylococcus epidermidis, Escherichia coli and Salmonella entereditidis and determination of MIC by dilution methode. The result showed that miana extract has the highest antibacterial activity on S. aureus and S. epidermidis. Miana extract was better than fresh and "infusan" miana leave on inhibition activity of S. aureus and S. epidermidis. MIC value of S. aureus and S. epidermidis were 3 mg/ml. The active fraction of maina leave extract contain phthalic acid derivates by GG-MS.
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Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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