Judul: Kajian Laju Deforestasi dan Degradasi Hutan Di Kabupaten Lamandau dan Kotawaringin Barat Provinsi Kalimantan Tengah
Abstrak: Issue of deforestation and forest degradation has been attracting the international and national community’s attention. This study was performed to identify rate and driving force of deforestation and degradation occurred in Lamandau and Kotawaringin Barat, Central Kalimantan Province. The study objective is to identify the rate and driving forces of deforestation as well as forest degradation using medium resolution image, Landsat TM. The classification method used to detect and analyze deforestation and forest degradation was visual interpretation, then followed by thematic change technique. Identification of deforestation and forest degradation driving force was done using a depth interview. The results of study show that the deforestation rate during the period of 1990-2013 is 56 408.3 ha/year, while forest degradation rate is 36 195.0 ha/year. The main driving forces of deforestation and forest degradation are opening up forest for road constructions, settlement establishment, estate crop and agriculture development. The major agents of deforestation and forest degradation are local community contributing of approximately 10%, while the rest was contributed by estate crop company (palm oil company).
Keyword: visual interpretation, thematic change, driving force, forest degradation, deforestation, Bogor Agricultural University (IPB)

Judul: Pendugaan Perubahan Cadangan Karbon di Kabupaten Lamandau dan Kabupaten Kotawaringin Barat, Provinsi Kalimantan Tengah.
Abstrak: Deforestation and forest degradation has been a world attention due to their contribution on the global warming. This study describes the estimation of carbon stock changes caused by forest and land cover change using thematic approach. Carbon stock changes was analyzed and detected by using thematic change technique and multi-temporal image analysis. This research focused on carbon stock changes and emissions of CO2 due to land cover changes in Lamandau and Kotawaringin Barat Regency, Central Kalimantan Province. The main objective of this research is to estimate carbon stock changes and emissions of CO2 in Lamandau and Kotawaringin Barat Regency, Central Kalimantan Province during the period of 1990-2000 and 2000-2013. The result of this study indicates that there was a decrease in carbon during the period of 1990-2013, having mean annual decrease of carbon stock at amount of 2 945 639 Mg/year or equivalent to the loss of forest (deforestation) area of 23 986.6 ha/year and forest degradation area of 2 442.4 ha/year or equivalent to emission of 1 878 549 car/year.
Keyword: degradation, deforestation, multi temporal image analysis, carbon stock, land cover change, Bogor Agricultural University (IPB)

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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