Judul: Pengaruh Electronic Word of Mouth dan Brand Image terhadap Keputusan Pembelian Kosmetik Somethinc pada E-Commerce di Jabodetabek
Abstrak: Kebutuhan akan produk kosmetik berakibat pada tinginya pengguna kosmetik di Jabodetabek. Pada tahun 2022 preferensi merek lokal mencapai 54%. Somethinc sebagai salah satu merek kosmetik lokal menduduki peringkat keempat sebagai kosmetik dengan pengguna terbanyak pada 2022. Meningkatnya pengguna internet di Indonesia dimanfaatkan juga untuk melakukan jual beli dengan memanfaatkan e-commerce. E-commerce sendiri menjadi media pembelian kosmetik terbesar pada 2022. Namun penjualan Somethinc tidak menentu dan industri kosmetik yang bertambah meningkatkan persaingan. Sehingga diperlukan strategi untuk meningkatkan penjualan. Penelitian ini bertujuan untuk menganalisis electronic word of mouth dan brand image terhadap keputusan pembelian kosmetik Somethinc pada e-commerce di Jabodetabek. Penelitian ini menggunakan data primer dengan menyebar kuesioner dan data sekunder yang bersumber dari buku, jurnal, dll. Metode penarikan sampel menggunakan teknik quota sampling dan diolah menggunakan metode analisis deskriptif dan SEM-PLS. Hasil penelitian menunjukkan adanya pengaruh yang positif dan signifikan antara electronic word of mouth dan brand image terhadap keputusan pembelian produk kosmetik Somethinc pada e-commerce di Jabodetabek., The need for cosmetic products results in a high number of cosmetic users in Jabodetabek. In 2022, the preference for local brands reached 54%. Somethinc as one of the local cosmetic brands is ranked fourth as the cosmetic with the most users in 2022. The increasing number of internet users in Indonesia is also used to buy and sell by utilizing e-commerce. E-commerce itself will be the largest medium for purchasing cosmetics in 2022. However, Somethinc's sales are erratic and the growing cosmetics industry increases competition. Therefore a strategy is needed to increase sales. This study aims to analyze electronic word of mouth and brand image on purchasing decisions for Somethinc cosmetics in e-commerce in Jabodetabek. This study uses primary data by distributing questionnaires and secondary data sourced from books, journals, etc. The sampling method uses quota sampling technique and is processed using descriptive analysis method and SEMPLS. The results showed a positive and significant influence between electronic word of mouth and brand image on purchasing decisions for Somethinc cosmetic products in e-commerce in Jabodetabek.
Keyword: brand image, e-commerce, electronic word of mouth, purchase decision

Judul: The Effect of Brand Image, Product Quality, Price and Promotion towards Consumer Purchase Intention of Somethinc Products in Jabodetabek
Abstrak: Industri kecantikan merupakan salah satu sektor bisnis dengan peningkatan yang pesat setiap tahunnya, sehingga menyebabkan munculnya banyak pelaku usaha baru di bidang tersebut. Akibat kesadaran yang meningkat tentang pentingnya menjaga kesehatan kulit, produk perawatan kulit telah menjadi salah satu barang yang dimiliki setiap orang. Tujuan dari penelitian ini adalah untuk mengidentifikasi karakteristik responden dan mengetahui bagaimana citra merek, kualitas produk, harga, dan promosi berdampak pada minat beli konsumen Somethinc. Selain itu, penelitian ini juga akan menganalisis faktor-faktor yang paling berpengaruh pada minat beli konsumen Somethinc di Jabodetabek. Metode Analisis deskriptif dan SEM-PLS digunakan untuk menganalisis data. Teknik pengambilan sampel yang diterapkan adalah voluntary sampling. Hasil penelitian menggambarkan bahwa faktor harga dan promosi memiliki pengaruh positif dan signifikan terhadap minat beli. Lebih lanjut, variabel promosi tampaknya memiliki pengaruh yang paling dominan terhadap minat beli.
Keyword: Brand Image, Product Quality, Price, Promotion, Purchase Intention

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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