Judul: Potensi Teh Herbal Lempuyang Gajah (Zingiber zerumbet L.) sebagai Antioksidan pada Tikus Sprague-Dawley Hiperkolesterolemia
Abstrak: Hypercholesterolemic conditions can increase lipid peroxidation and as an indicator of the presence of free radicals in the body. This research aimed to determine the efficacy of lempuyang gajah (Zingiber zerumbet L.) herbal tea as an antioxidant to prevent lipid peroxidation in hypercholesterolemic rats. Twenty six rats were divided into 4 following groups: normal, hypercholesterolemia, extract 1 (low dose), and extract 2 (high dose) groups. Hypercholesterolemia were induced in rats by high cholesterol diet (1.5% cholesterol) and oral administration of propil tiourasil (PTU) 0.5 mg/kg bw in six weeks. Before necropsied, rats were given standard diet for the last four weeks. Lipid peroxide concentrations in the liver were analyzed using thiobarbituric acid (TBA) assay with spectrofotometer UVVis at 532 nm. Results showed that feeding cholesterol free diet in the last four weeks normalized liver lipid peroxide concentration in the three treatment groups. The average of all groups were 40.88±13 nmol/g (p=0.317). Addition of extract reduced correlation between liver lipid peroxide concentration and blood cholesterol concentration on the extract groups (1 and 2). This observation suggest that components of lempuyang gajah herbal tea can prevent lipid peroxidation in liver.
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Judul: Teh herbal lempuyang gajah sebagai penurun lipid peroksida darah tikus hiperkolesterolemia
Abstrak: The lempuyang gajah herbal tea has been reported to reduce blood cholesterol concentration, but reports on its potency to reduced blood lipid peroxide concentration is not known. The objective of this research is to determine the potency of this mixture of lempuyang gajah (Zingiber zerumbet L.) and green tea (Camellia sinensis) as antioxidant in vivo, particularly in hypercholesterolemic condition. Twenty six rats were divided into normal group and cholesterol feed group. Cholesterol feed group (HK) were divided into 3 groups: hypercholesterolemic (HK I), herbal tea dosage 1 (HK II), herbal tea dosage 2 (HK III). Hypercholesterolemia was induced by cholesterol diet (1.5%) and PTU (0.01%) administered orally for 6 weeks. Afterward, animals were given cholesterol free standard diet. Extract of herbal tea were administered orally for another 4 weeks with dosage of lempuyang gajah:green tea= 1:2 (dosage 1) and 2.5:2 (dosage 2). Lipid peroxide concentration was analyzed in week-0,2,4,6,8, and 10 using spectrophotometry method at 533 nm. Cholesterol fat and PTU induction significantly (p<0.05) increased lipid peroxide concentration in blood of HK (40.31%) compared with normal group. Reduction in blood lipid peroxide concentration of HK III was more (40.50%) than HK II (32.57%) at the end of experiment.
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Judul: Pembangunan Perumahan Pada Wilayah Desakota Kaitannya Dengan Sistem Sosial Masyaraka t Asli
Abstrak: Faktor utama yang banyak mempengaruhi meningkatnya jumlah perumahan dan pemukiman pacta wilayah desakota adalah adanya tekanan populasi sebagai akibat dari migrasi besar-besaran menuju daerah desakota. Dengan kata lain, lokasi perumahan atau pemukiman menjadi tak memiliki banyak pilihan lagi, kota telah sesak dan sasaran selanjutnya para pengais materi di daerab kota adalab wilayah desakota. Masyarakat asli yang sejak lama tinggal di wilayah desakota merupakan bagian dari masyarakat desakota yang perlu diperhatikan. Baik disadari maupun tidak disadari, perubaban pada masyarakat asli desakota akan terjadi karena masyarakat selalu dalam keadaan dinamis. Selain itu perubahanjuga akan terjadi dikarenakan masyarakat adalah sistem yang terdiri dari bagian-bagian yang berhubungan serta berintegrasi secara fungsional, sehingga perubaban pada satu fungsi dari masyarakat akan mempengaruhi fungsi lainnya.
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