Judul: Gambaran Diferensial Leukosit Mencit (Mus Musculus) Setelah Pemberian Berbagai Dosis Nano Logam Besi (Fe) Secara Intraperitonial
Abstrak: Besi dalam tubuh berperan penting dalam pembentukan sel darah merah dan bagian dari enzim hemoprotein. Penelitian ini bertujuan untuk mengkaji pengaruh pemberian nano logam besi (Fe) terhadap persentase differensial leukosit mencit (Mus musculus). Hewan coba yang digunakan dalam penelitian ini sebanyak 30 ekor mencit berumur 10 minggu dan diinjeksikan secara intraperitonial larutan logam Fe. Mencit dibagi dalam 6 kelompok yaitu kontrol negatif (tidak diberi logam Fe), logam Fe dosis 8,3 mg/mL, logam Fe dosis 24,8 mg/mL, logam Fe dosis 41,25 mg/mL, logam Fe dosis 57,8 mg/mL dan logam Fe dosis 74,3 mg/mL. Hasil penelitian menunjukkan rata-rata persentase neutrofil, eosinofil dan monosit mengalami peningkatan. Persentase basofil rata-rata berada dalam rentang normal, sedangkan persentase limfosit cenderung menurun dibandingkan sebelum perlakuan. Pemberian nano logam Fe memberikan pengaruh secara signifikan terhadap gambaran leukosit darah mencit.
Keyword: diferensial leukosit, nano logam besi, mencit

Judul: Gambaran Leukosit Mencit (Mus Musculus) Setelah Pemberian Partikel Nano Logam Mangan (Mn)
Abstrak: Mangan merupakan mineral mikro dalam jumlah yang sangat kecil di dalam tubuh, namun mempunyai peranan esensial untuk kehidupan dan kesehatan. Tujuan penelitian ini yaitu mengkaji pengaruh pemberian partikel nano logam mangan (Mn) terhadap persentase diferensial leukosit mencit (Mus musculus). Hewan coba yang digunakan adalah mencit putih yang diberi partikel nano logam Mn. Penelitian ini menggunakan rancangan acak lengkap dengan lima ulangan. Mencit dibagi dalam enam kelompok yaitu 1) kontrol negatif atau KN (tidak diberi partikel nano logam), 2) D1 (diberi partikel nano logam Mn dengan dosis 100 mg/kgBb), 3) D2 (diberi partikel nano logam Mn dengan dosis 300 mg/kgBb), 4) D3 (diberi partikel nano logam Mn dengan dosis 500 mg/kgBb), 5) D4 (diberi partikel nano logam Mn dengan dosis 700 mg/kgBb), 6) D5 (diberi partikel nano logam Mn dengan dosis 760 mg/kgBb). Hasil penelitian menunjukkan bahwa pemberian partikel nano logam Mn secara keseluruhan tidak mempengaruhi persentase jumlah leukosit yang signifikan. Persentase leukosit masih dalam keadaan normal setelah pemberian partikel nano logam Mn.
Keyword: leukosit, logam Mn, mencit

Judul: Characteristic of Overshooting Top (OT) Based on  Himawari  8  Satellite  as  a  Convective  Cloud  Feature  that  Generates  Extreme Weather in the Java Island Region
Abstrak: Overshooting Top (OT) is a feature at the top of a convective cloud that is associated with extreme weather. Research on OT in tropical Indonesia is still very limited. The existence of geostationary satellites with wide area coverage and fast frequency observations is useful for observing the fast dynamics of the OT life cycle. Therefore, this study intends to analyze the relationship between OT and extreme weather, updraft and thermodynamic conditions of OT when extreme weather occurs, the best objective method for detecting OT in the day time and night time, and the spatiotemporal distribution of OT in the tropical region of Java Island during the 2018-2021 period. Based on visual analysis using visible channel and Himawari 8 sandwich products, 87% of extreme weather events in Java were accompanied by the appearance of OT. It indicates that the presence of the OT pattern is a convection cloud pattern or feature that is closely related to extreme weather events for the Java Island region. The existence of a time lag between the appearance of OT and extreme weather events on Java Island indicates that the OT of convection cloud can be used as a precursor or nowcasting for the appearance of extreme weather. Most of the convective cloud OT features during extreme weather events on Java Island have altitude that were only able to exceed the altitude of the equilibrium level and few were able to exceed the tropopause level of 9 km – 16 km. The difference in atmospheric conditions during extreme weather events on Java Island, which is in the tropics and subtropics, is a strong and unstable convective energy condition characterized by a larger CAPE, as well as unstable KI, LI, SI and TTI values. It is offset by kinematic factors in the form of a weak vertical wind shear (bulk wind shear 0-6 km) and a higher freezing point height. The difference between extreme weather events in the Java Island region and other tropical regions compared to subtropical regions is the strong updraft speed of convection clouds. The IRW Texture COMB algorithm based on the IRW-Texture Gradient modification and the COMB algorithm shows a significant increase in quality for detecting OT and non-OT pixels in Java. Rainy days with rainfall > 50 mm/day are very common in areas with an altitude of > 500 m. On the other hand, the level of convection activity which is indicated by the presence of OT and lightning is significantly reduced in this area. OT of convective clouds appear more frequently during the DJF season and less frequently during the JJA season. OT often appears during the day time and rarely at night time. Most OTs appear in the central part, away from the south and north coasts of Java Island during the day, while OTs that appear near the south and north coasts of Java Island can appear in the morning or afternoon.
Keyword: convective clouds, extreme weather, Overshooting Tops, Himawari 8 Satellite