Judul: The Potency Test of Black Turmeric (Curcuma eroginosa Roxb.) in Broiler were Infected with H5N1 Avian Influenza Virus: Histopathology of Liver and Kidney.
Abstrak: Avian Influenza is one of the zoonotic disease which is very dangerous and not yet to be controlled optimally. The aim of this resarch was to observe the potency of black turmeric (Curcuma aeroginosa Roxb.) extract in preventing the infection of H5N1 virus through liver and kidney histopathologycal discriptions. This research used Cobb strain of Broiler which were devided into 4 groups included K1 (extract treatment), K2 (no extract treatment and no virus infection), P1 (extract treatment and virus infection), and P2 (virus infection). Black turmeric extract was given to Broiler during 3 weeks in postal system cage and then the Broiler were infected by H5N1 virus in Biosafety Laboratory level 3 facilities. The quantitative data obtained by scoring and then were analyzed by Kruskal Wallis and Dunn test. The result revealed that the death of Broiler which were treated with Curcuma aeroginosa Roxb. extract and were infected with H5N1 virus could be obstructed. The histopathological lesions such as hemorrhage, inflammatory focuse, necrose in liver, and also inflammatory focuse and necrose in kidney could be reduced.
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Judul: The immunohistochemistry study of chicken infected by H5N1 virus after being treated with extracts of herbal medicine with various solvents.
Abstrak: The research aims at knowing the distribution of H5N1 virus antigen in chicken organs by using immunohistochemistry methods and to investigate the potential of herbal medicine Andrographis paniculata Nees (Andrografolide), Curcuma aeruginosa Roxb (curcuma), Piper crocatum Ruiz (piperine) and Illicium verum Hook (anethol) in inhibiting H5N1 virus infection in broiler chickens. One hundred and five day old chick (DOC) broilers were divided into 7 groups with each group of 15 individuals. DOC maintained by fed and water ad libitum and given oral plant extracts in the form of formulations every day for 21 days, starting from 7 to 28 days old. The chickens were infected with H5N1 virus intranasally with 0,1 ml 106EID50. The treatment group I-1, I-2, I-3 of chickens were given a combination of extracts I (andrographolide, curcumin, piperine and anetol) with the solvent of hexane, ethyl acetate and ethanol. The treatment group II-1, II-2, II- 3 of chickens were given a combination of extracts II (andrographolide, piperine and anetol) with the solvent of hexane, ethyl acetate and ethanol. The results showed that the antigen can be detected in all chicken organs (trachea, lung, liver, pancreas, intestine, spleen and bursa Fabricius) in each treatment and in the positive control groups. In conclusion, besides mortality data, histopathologic description and distribution of the H5N1 viral antigen of all chicken organs tested, lead to the formula of extracts with andrographolide, anethol and piperine with the ethanol solvent in group II-3 has higher antiviral activity than other groups.
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Judul: Formulasi Hamiltonian untuk Menggambarkan Gerak Gelombang Soliter Dimensi Tiga di Permukaan Laut
Abstrak: Gelombang permukaan adalah gelombang yang terjadi perbedaan rapat massa antara air dan udara. Salah satu gelombang permukaan yang ditinjau adalah gelombang soliter. Formulasi gelombang soliter dilakukan dengan menggunakan formulasi Hamiltonian.
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