Judul: Penampilan produksi domba ekor tipis jantan dengan rasio pakan  rumput lapang dan ampas tahu yang berbeda
Abstrak: This research was conducted in Mitra Tani Farm from August until October 2005. Research was conducted to examine performance of male thin tailed sheep which have been given feed at different ratio. Sixteen male thin tailed sheep were used in this research. Sheep was placed in an individual cage and divided into 4 groups.
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Judul: Performa Dan Morfometrik Domba Ekor Gemuk Dengan Pemberian Pakan Konsentrat Dan Limbah Tauge Pada Taraf Pemberian Yang Berbeda
Abstrak: Performance and morphometric are a description of conditions which reflect the growth and development of livestock. Generaly, these are influenced by genetic and environmental factors. Genetically, fat tailed sheep is one of a local sheep, which is fast in growth and can adapt in the tropical climate. Feed is one of the environmental factor, which can influence the growth. This research was conducted to determine the performance and morphology of fat tail sheep male (under one year old) that fed by concentrate and sprouts waste at different levels, they were P1 = 100% concentrate + 0% sprouts wastes, P2 = 75% concentrate + 25% sprouts wastes, P3 = 50% concentrate + 50% sprouts wastes and P4 = 25% concentrate + 75% sprouts wastes. The sheep were classified into two groups are small and large body weight. The Data were analyzed using randomized block design with four treatments and two blocks. The results of this research show that the treatments had significantly (P<0.05) influenced the sheep performance but they do not have significant result on the sheep morphometric.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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