Judul: Pengembangan proses produksi bioinsektisidaoleh Bacillus thuringiensis subsp. israelensis secara curah menggunakan substrat onggok
Abstrak: The research was aimedat developing the technique of producing bioinsectiside from Bacillus thuringiensis subsp. israelensis with specific objectives (1) to obtain the basis of calculation to scale up the bioreactor scale from 2 liters to 13 liters with "onggok" medium and batch system (2) to obtain information on the characteristics of bioinsectiside producer and (3) to find out description on feasibility and financial analysis of the bioinsectiside production at industrial scale
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Judul: Proses Produksi Bioinsektisida Bacillus thuringiensis Isolat Lokal Menggunakan Limbah Agroindustri pada Kultivasi Media Padat.
Abstrak: Due to increased awareness of the need for safe insecticide, currently the use of bioinsecticide is increasingly in demand by farmers who want to produce vegetables and fruits safe for consumption. Also, it is used in the control of mosquito larvae that can be vectors of several dangerous diseases. The use of safe insecticides is needed, so as not to pollute the soil, water and other living creatures. The advantages of using microbial bioinsecticide are safe, environmentally friendly, specific to certain insect pests, not harmful to pets, do not result in residues on crops and soil. The purpose of this research was to develop the production process of bioinsecticide (Bacillus thuringiensis) using local isolates with starter and cultivation media of agroindustrial by products, using solid state cultivation, in order to obtain bioinsecticide that is cheap and easy to produce. The purpose of each stage are to obtained isolate characteristics suitable with the solid state cultivation and suitable with climatic environment in Indonesia, development of starter from agroindustrial waste, design the condition of solid state cultivation production process using agroindustrial waste, and for evaluation and analysis of efficacy in the target insects. The stages of research began from isolate isolation from Attacus atlas and Bombyx mori caterpillar carrions. Isolates further obtained were then characterized and identified to obtain B. thuringiensis, from both isolates obtained, it was then selected one of the most suitable for solid state cultivation. The next stage was the selection of starter medium from agroindustrial waste, followed by a bioinsecticide production using the mixed media of sago lees and iles-iles lees by solid state cultivation. Bioinsecticide produced was characterized by amino acid content protein profiles and toxicity ability against A. aegepty larvae dan C. pavonana larvae. B. thuringiensis producing endotoxins that served as a bioinsecticide active ingredient could be isolated from A. atlas and B. mori caterpillar carrions from Bogor, Indonesia. The isolate characteristics of A. atlas caterpillar are the bacteria belonging to Gram-positive, having flagella, punctiform shaped colonies, slimy, white, rod-shaped vegetative cells with a length of approximately 1700 nm and a width of about 830 nm. The protein crystals yielded are spherical, with a diameter of 470-770 nm, and diameter of spore of 550-750 nm. The isolate characteristics of B. mori caterpillar are, belonging to Gram-positive bacteria, motile, circular, white and slimy, long and round vegetative cells with a length approximately of 3900-9500 nm and a width approximately of 830 nm. The protein crystals yielded are spherical, bipyramid and cuboid with a size of 300-700 nm, and diameter of spore of 500-750 nm. Philogenetic tree reconstruction showed that both isolates are in the same cluster with B. thuringiensis. Of two selected isolates, for bioinsecticide production by solid state cultivation is isolates from A. atlas. Selection of isolate is based on the nature of higher motility characteristic, cell growth, the number of spores produced and their toxicity against the test insects. Starter media is selected based on the growth parameters of B. thuringiensisin tofu whey media, tofu whey plus urea, coconut water, and nutrient broth. It is obtained the
Keyword: Bioinsecticide, solid-state cultivation, B. thuringiensis, solid waste sago, solid waste iles-iles

Judul: Klasifikasi Kanker Payudara Berdasarkan Citra Histopatologi Menggunakan Model Convolutional Neural Network
Abstrak: Kanker payudara menempati peringkat pertama sebagai jenis kanker yang paling umum diderita oleh perempuan di dunia. Kanker payudara memiliki kontribusi sebesar 11,7% dari total kasus baru kanker di dunia dan 16,6% di Indonesia secara keseluruhan yang tercatat pada tahun 2020. Pemeriksaan kanker umumnya menggunakan biopsi dengan melakukan pengambilan sampel jaringan yang dicurigai terdapat sel kanker. Penelitian ini bertujuan untuk membuat model convolutional neural network dalam memprediksi status kanker payudara pada citra histopatologi dengan performa paling baik. Data yang digunakan dalam penelitian ini bersumber dari dataset BreakHis yang terdiri atas 7909 citra histopatologi jaringan tumor payudara dengan 2 kelas yaitu, jinak dan ganas. Tahapan dalam penelitian ini meliputi praproses data, pembagian data, hyperparameter tuning, pelatihan model, dan evaluasi model. Hasil dari penelitian ini adalah satu buah model convolutional neural network dengan arsitektur DenseNet201 yang dapat memproses klasifikasi kanker payudara pada citra histopatologi. Model ini memiliki akurasi senilai 98,74%.
Keyword: breast cancer, convolutional neural network, histopathology