Judul: Perubahan Tutupan Lahan di Taman Nasional Bukit Barisan Nama NIM Selatan Provinsi Lampung
Abstrak: National Park is a conservation nature area which has function to protect life support system, maintain flora fauna and its ecosystem, which is managed by zonation system. The zonation can be divided into core zone, utilization zone and other based on the necessity. However, National Park is still facing problem such as illegal poaching, illegal logging, forest encroachment, and agrarian conflict to national park border. One of national park which has such kind of problem is Bukit Barisan Selatan National Park. The research is aimed at investigation of land use/land cover and its causes. After conducted the research by using GIS and interviewed some participants, the result showed that forest cover is decreased during period of 1991 to 2013. This decrease is due to forest encroachment, in which forest was converted into coffee plantation. In fact, it was happened before the National Park establishment.
Keyword: Bogor Agricultural University (IPB), land cover change., forest encroachment, Bukit Barisan Selatan national park

Judul: Analisis Perubahan Penutupan dan Pola Pemanfaatan Lahan di Taman Nasional Gunung Halimun Salak Menggunakan Sistem Informasi Geografi (SIG) (Studi Kasus: Kampung Adat Lebak Picung)
Abstrak: Gunung Halimun Salak National Park (GHSNP) is one of the conservation areas that have been facing forest cover changes rapidly. It’s related to people activities in and around the area. One of the communities which have been living at surround the GHSNP is indigenous peopleof Kampung Lebak Picung, Desa Hegarmanah, Kecamatan Cibeber, Kabupaten Lebak, Banten. They have been practicing shifting cultivation system. It is feared the system willm lead to forest conversion in GHSNP area. Data and information of the conditions in Kampung Lebak Picung area can be analyzed through technology Geographic Information System (GIS). The aim of this research is to study land cover changes in Kampung Lebak Picung, to investigate factors that influence land cover change, and review procedures of land management by the community at Kampung Lebak Picung Social data, and ground control point were taken in Kampung Lebak Picung for one month in June 2009. Collected data included spatial data in the form of maps, Landsat image TM and ETM + in 1989, 1997, 2007 and attribute data include sociocultural conditions, management and land use, and people perception. Spatial data were prossed by using Geographic Information System technology and Remote Sensing. The result of image processing were analyzed qualitatively using the attribute data to determine its impact on land cover changes. Land cover types in Kampung Lebak Picung consist of forest, mixed gardens, shrubs, fields, rice fields, water bodies, open land, built up land, and no data. In the period 1989-2007, rice fields land cover type were decrease. Meanwhile fields and water body land cover type were increase. In general, several types of land cover area fluctuated. Fluctuations occur on forest land cover, mixed gardens, shrubs, and open land types. In 1997, forest area were increase 20,47 ha but mixed garden and shrubs decrease of 41.93 ha and 3.27 ha. In 2007, forest land cover types decreased of 19.28 hectares but shrubs were increase 2,50 ha. Land cover changes were influenced by the increasing population and implementation of shifting cultivation system to arable land use (mixed garden and fields). Most of income source is farmers (91.67%) therefore usage of arable land (paddy fields, fields, and mix gardens) was very high. It’s feared, it will lead to forest conversion to arable land. In fact for this period of reseaerch arable land is sufficient to meet the needs of the community. Generally, people had high perception for the existence of forest, but people's knowledge of the forests and national parks are still quite low. Factor that influence land cover change are social condition, especially in land management systems. To anticipate expansion of cultivation land into forest area, the National park should alocate those activities in spesific area/zone.For that purpose the National Park should supervise the activities.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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