Judul: Aktivitas Ekstrak Etanol Daun Sirih Hijau (Piper betle Linn.) dalam Mempercepat Proses Persembuhan Luka pada Tikus
Abstrak: The aim of this study was to examine the activity of betel ethanol extract for abration skin wound healing process in Sparague-Dawley rats based on gross and microscopic observation (including histopatological and touch specimen). Under aseptic conditions four paravertebral full thickness skin incision performed on the back of 9 male rats. Every wounds were treated with different treatments. The treatments were control, placebo, commercial ointment, and extract betel. Histopatological section from tissue specimens were stained by hematoxylin and eosin and evaluated on first seven days and second seven days after surgery. Touch specimens were stained by Giemsa and evaluated on fourth and tenth day after surgery. The parameters of histopatological are reepitelization, fibroblas, congestion, bleeding, scrab formation, infiltration of inflammatory cell, hair follicle formation, and edema. Afterward, the specimens were grouped in phase of wound healing. Specimens touch parameter was the presence of inflammatory cells. The data were presented descriptively as quantitative data. Macroscopic appearances show that diameter extensive of betel ethanol extract wounds were decrease faster than other treatments. Scoring results of wounds who treated with betel ethanol extract in first seven days and second seven days show that wounds have entered maturation phase compared to other treatment. The specimens touch show that wounds who treated with betel ethanol extract were presenting inflammatory cells in first seven days. The results of this study show that wounds who treated with betel ethanol extract were recover faster than other treatment.
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Judul: Aktivitas Ekstrak Etanol Daun Sirih Hijau (Piper betle Linn.) dalam Proses Persembuhan Luka Infeksi Staphylococcus aureus pada Tikus
Abstrak: This research was aimed to prove the wound healing activity of Piper betle leaves ethanol extract against Staphylococcus aureus infection in rat skin. Various parameters such as pathology anatomy, netrofil presence, and microscopic observation were studied to evaluate the wound healing activity of Piper betle. Nine rats Sprague Dawley strain were used through our the study and each rat was given four treatments. Treatments were control, commercial ointments, akuadest, and Piper betle leaves ethanol extract. The experiment were given for fourteen days. Each of rats was aseptically wounded with four wounds in 1x1 cm2 square shape at the back of rats. Every wound was spilled by Staphylococcus aureus at 1st, 4th, 7th, and 11th day. All data were analyzed with descriptive semiquantitative method. Scoring results show that the first week of wounds treated with piper betle leaves ethanol extract had shown proliferative phase, while the second week treated with betle leaves extract had shown maturation phase. Wound treated with Piper betle leaves extract were healed better than others in the first week. Bassed on the results, Piper betle leaves extract can be used to heal bacterial wound in the skin
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Judul: Metrik Einstein (Anti-) Self-Dual Berdimensi Empat dengan Metode Cartan
Abstrak: Gravitational field equation can be formulated in differential forms (differential geometry), which describes gravity as a manifestation of the curvature of space-time. Curvature of space-time is characterized by a metric that satisfies the gravitational field equation. With differential forms it can be formulated the (anti-) self-dual Einstein equation, which is a modification of the Cartan structure in (anti-) self-dual basis. Calculation of (anti-) self-dual metric with (anti-) self-dual Einstein equation is simpler than the calculation using Christoffel symbols.
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