Judul: Pengaruh Pemberian Kitosan dan Nanokitosan dari Cangkang Rajungan (Portunus pelagicus) terhadap Kadar Trigliserida Tikus Sprague-dawley
Abstrak: Hipertrigliseridemia adalah salah satu kelainan metabolisme lipid yang ditandai dengan peningkatan fraksi lipid dalam plasma. Kitosan mampu menyerap lemak sehingga mampu menurunkan kadar lipid. Tujuan penelitian ini adalah membandingkan pengaruh pemberian kitosan dan nanokitosan terhadap kadar trigliserida tikus Sprague-dawley. Penelitian ini dilakukan beberapa tahap, yaitu karakterisasi kitosan, pembuatan nanokitosan, serta uji in vivo kadar trigliserida. Hasil PSA yang dilakukan sebanyak 3 ulangan menghasilkan rata-rata distribusi ukuran partikel sebesar 234,09±31,25 nm. Viskositas intrinsik dan berat molekul kitosan berturut-turut yaitu 26,16±1,03 cP dan 2586,24±186,00 kDa, sedangkan nanokitosan yaitu 0,38±0,09 cP dan 9,84±3,17 kDa. Nanokitosan dosis 200 mg/kg bb/hari dapat menurunkan kadar trigliserida sebesar 63,33±32,58 mg/dL atau 50,94±48,79% dari 124,33±46,11 mg/dL menjadi 61,00±18,03 mg/dL…
Keyword: Chitosan, Nanochitosan, Triglycerides, Sprague-dawley, Crab shell, Fraksi lipid, Molekul kotosan, Rats, Lipid metabolism

Judul: Pengaruh Pemberian Kitosan terhadap Kadar Trigliserida Darah & Berat Badan Tikus Sprague-dawley yang Diberi Pakan Asam Lemak Trans
Abstrak: This study was aimed to analyze chitosan intake on plasma triglyceride levels and body weight in rats Sprague-dawley fed by trans fatty acid. This study was experimental study with Post Test Only Control Group Design. The subjects were male Sprague-dawley rats, 2 months old. The subjects were divided in to 1 control (K) and 3 treatment groups which received chitosan as much as 0.035 g (P1), 0.045 g (P2), and 0.055 g (P3). Fed with high-fat diet was given by melted margarine as source of trans fatty acids as much as 1.7 g per day for 4 weeks. Measurement of triglyceride levels was done at second week dan fourth week after intervention and the body weight was weighed once per 3 days. The study revealed that feeding of margarine in a dose of 1.7 g per day increased body weight most high in K0 amount 32.1% or 63.8 g during 2 weeks and 54% or 107.2 g during 4 weeks intervention. The average of triglyceride levels K (254.3±49.0 mg/dL) and P1 (241.7±58.5 mg/dL) at second week. The average of triglyceride levels K (175.3±67.7 mg/dL) and P1 (181.3±40.1 mg/dL) at fourth week. Both of second and fourth week the average of triglyceride levels K and P1 were cathegorize in hypertriglyceridemia. Chitosan intake on fed inhibited increasing body weight on P2 (0.045 g) amount 53.4 g or 23.3% during 2 weeks and 63.6 g or 27.8% during 4 weeks. Chitosan intake 0.045 g on P2 decreased triglyceride levels (128.3±14.3 mg/dL) significantly than K (p=0.009) at second week. Thus, there were an opotimum dose of chitosan influence body weight and trigliceride levels.
Keyword: trans fatty acids and triglyceride, chitosan, body weight, Bogor Agricultural University (IPB)

Judul: Query Expansion based on Bilingual Dictionary Using Conditional Probability
Abstrak: Query expansion is a technique that can be used to bridge vocabulary gaps between queries and documents in the collection. With query expansion, user will be helped to formulate queries well so that user will optimize the search result. In this study, the expansion term was resulted from the translation of bilingual dictionary. Subsequently, several terms of expansion were elected based on the closeness of its relationship with the original query. This research showed that conditional probability can be used to select expansion term in bilingual translation method query expansion. The result of 1000 documents was more than 97% relevan document can be retrieved by this system. The more expansion term used, the larger number relevan document was retrieved.
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