Judul: Mapping of Coastline Changes in the Coastal of Bantul Regency Using Sentinel-2A Satellite Imagery
Abstrak: Pesisir merupakan wilayah yang kompleks akibat interaksi darat dan laut sehingga mudah mengalami perubahan secara fisik seperti perubahan garis pantai. Perubahan garis pantai penting diketahui untuk kajian pengelolaan kawasan pesisir, pemodelan pesisir, studi akresi-abrasi, serta analisis wilayah bahaya. Penelitian bertujuan memetakan dan menghitung laju perubahan garis pantai di Kabupaten Bantul, Daerah Istimewa Yogyakarta menggunakan citra Sentinel-2A pada tahun 2017, 2018 dan 2021. Metode digital shoreline analysis system (DSAS) digunakan untuk menghitung perubahan garis pantai secara statistik maupun geospasial. Lokasi penelitian terbagi menjadi 15 sub-zona dimana abrasi tertinggi terjadi pada Desa Parangtritis bagian timur (Sub-zona E3) dengan laju perubahan garis pantai mencapai -10,03 m/tahun. Abrasi dipengaruhi landainya kondisi pantai, gelombang dengan tinggi mencapai 2,39 m dan arus dengan kecepatan mencapai 0,24 m/s yang menggerus garis pantai serta tidak adanya penghalang di kawasan pantai. Akresi tertinggi terjadi di Desa Parangtritis bagian barat (Sub-zona E1) dengan laju perubahan garis pantai mencapai 9,20 m/tahun. Akresi dipengaruhi material sedimen dari darat yang mengendap dan menambah area garis pantai serta bergeraknya pasir oleh angin di sekitar gumuk pasir., Coastal is a complex area due to land and sea interactions so that it is easy to experience physical changes such as changes in coastlines. Coastline changes are important to know for coastal area management studies, coastal modeling, accretion-abrasion studies, and hazard area analysis. The study aimed to map and calculate the rate of change in coastlines in Bantul Regency, Yogyakarta Special Region using Sentinel-2A imagery on 2017, 2018 and 2021. The digital shoreline analysis system (DSAS) method used to calculate shoreline changes statistically and geospatially. The research location divided into 15 sub-zones where the highest abrasion occured in east Parangtritis Village (E3 sub-zone) with a coastline change rate of -10,03 m/year. Abrasion influenced by gentle coastal conditions, waves with a height of 2.39 m and currents with a speed of 0.24 m/s which erodes the coastline and there is no barrier in the coastal area. The highest accretion occurred in west Parangtritis Village (E1 sub-zone) with a coastline change 9,20 m/year. Accretion influenced by sedimentary material from land that settled and added to the coastline area and the movement of sand by the wind around the sand dune.
Keyword: abrasi, akresi, DSAS, Kabupaten Bantul, abrasion, accretion, Bantul Regency

Judul: Mapping of Coastline Changes in the Coastal of Bantul Regency Using Sentinel-2A Satellite Imagery
Abstrak: Pesisir merupakan wilayah yang kompleks akibat interaksi darat dan laut sehingga mudah mengalami perubahan secara fisik seperti perubahan garis pantai. Perubahan garis pantai penting diketahui untuk kajian pengelolaan kawasan pesisir, pemodelan pesisir, studi akresi-abrasi, serta analisis wilayah bahaya. Penelitian bertujuan memetakan dan menghitung laju perubahan garis pantai di Kabupaten Bantul, Daerah Istimewa Yogyakarta menggunakan citra Sentinel-2A pada tahun 2017, 2018 dan 2021. Metode digital shoreline analysis system (DSAS) digunakan untuk menghitung perubahan garis pantai secara statistik maupun geospasial. Lokasi penelitian terbagi menjadi 15 sub-zona dimana abrasi tertinggi terjadi pada Desa Parangtritis bagian timur (Sub-zona E3) dengan laju perubahan garis pantai mencapai -10,03 m/tahun. Abrasi dipengaruhi landainya kondisi pantai, gelombang dengan tinggi mencapai 2,39 m dan arus dengan kecepatan mencapai 0,24 m/s yang menggerus garis pantai serta tidak adanya penghalang di kawasan pantai. Akresi tertinggi terjadi di Desa Parangtritis bagian barat (Sub-zona E1) dengan laju perubahan garis pantai mencapai 9,20 m/tahun. Akresi dipengaruhi material sedimen dari darat yang mengendap dan menambah area garis pantai serta bergeraknya pasir oleh angin di sekitar gumuk pasir., Coastal is a complex area due to land and sea interactions so that it is easy to experience physical changes such as changes in coastlines. Coastline changes are important to know for coastal area management studies, coastal modeling, accretion-abrasion studies, and hazard area analysis. The study aimed to map and calculate the rate of change in coastlines in Bantul Regency, Yogyakarta Special Region using Sentinel-2A imagery on 2017, 2018 and 2021. The digital shoreline analysis system (DSAS) method used to calculate shoreline changes statistically and geospatially. The research location divided into 15 sub-zones where the highest abrasion occured in east Parangtritis Village (E3 sub-zone) with a coastline change rate of -10,03 m/year. Abrasion influenced by gentle coastal conditions, waves with a height of 2.39 m and currents with a speed of 0.24 m/s which erodes the coastline and there is no barrier in the coastal area. The highest accretion occurred in west Parangtritis Village (E1 sub-zone) with a coastline change 9,20 m/year. Accretion influenced by sedimentary material from land that settled and added to the coastline area and the movement of sand by the wind around the sand dune.
Keyword: abrasi, akresi, DSAS, Kabupaten Bantul, abrasion, accretion, Bantul Regency

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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