Judul: Gambaran Histomorfologi Hati, Usus Halus, dan Limpa pada Tikus Hiperglikemia yang Diberi Ekstrak Sambiloto
Abstrak: REZI ZAHRA AZIZA. B04051740. Histomorphological Aspect of Liver, Small Intestine, and Spleen of Diabetic Model Rat that was Treated with Sambiloto Extract. Under direction of ADI WINARTO and EKOWATI HANDHARYANI The purpose of this study is to evaluate the histomorphological aspect of liver, small intestine, and spleen of diabetic model rats that were treated with sambiloto extract. Twenty-four male Spraque-Dawley rats were divided into 2 groups of models. Diabetic model group was induced by Streptozotocin (40 mg/kg BW) intra-peritonially, and a healthy group which recieved Phosphat Buffer Saline (PBS) pH 7.4 intra-peritonially. The both of groups were treated with sambioto daily within 4 weeks. Rat model of diabetes with low sugar levels and high at the time of sacrifice was observed as a distinct group. Observations on the liver, small intestine, and spleen of non-diabetic group showed that the provision does not affect the morphological sambiloto liver, small intestine, and spleen. Observations on liver of rat diabetic model with blood sugar levels are still high indicates a change in the form of congestion and degeneration, in the small intestine seen an increase in the number of Goblet cells and mitotic cells but did not find any picture of damage to the mucosal epithelium. Changes are seen in the spleen leads to degeneration until necrosa, and spleen increased with the emergence of readiness germinal centers. Evaluation of the liver, small intestine, and spleen model of diabetes with a decrease in blood sugar showed an improvement histomorfologis picture to approach the image on the non-diabetic group. Keyword :Diabetic, Sambiloto, Liver, Small Intestine, Spleen
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Judul: Perubahan Histomorfologis Testis dan Ginjal Tikus Model Diabetes Pascapencegahan dengan Ekstrak Sambiloto (Andrographis paniculata).
Abstrak: Penelitian ini bertujuan mengevaluasi perubahan gambaran histomorofologis testis dan ginjal tikus model diabetes pascapencegahan dengan ekstrak sambiloto infusum dan sokhletasi. Tikus model terdiri atas empat kelompok. Kelompok pertama adalah tikus kontrol, yaitu tidak diberikan perlakuan apapun. Kelompok kedua adalah tikus model diabetes, yaitu dengan injeksi streptozotosin (STZ) sebagai pemicu tejadinya hiperglikemik. Kelompok ketiga adalah tikus yang diberi pencegahan dengan ekstrak sambiloto infusum dan kelompok keempat adalah tikus yang diberi pencegahan ekstrak sambiloto sokhletasi. Penelitian ini dilakukan selama 14 hari, lalu dilakukan nekropsi dengan mengambil organ testis dan ginjal yang diawetkan untuk pewarnaan Haematoxilin-Eosin. Hasil menunjukan penggunaan ekstrak sambiloto infusum dan sokhlet mengalami penurunan kadar glukosa darah,terutama pada ekstrak sambiloto infusum yang dapat menurunkan kadar glukosa hingga angka normal. Pencegahan ekstrak sambiloto infusum dan sokhletasi mampu mempertahankan keadaan sel-sel spermatogenik pada testis dan berkurangnya kejadian degenerasi, nekrosa serta endapan protein pada jaringan di korpuskulus renalis. Ekstrak sambiloto infusum lebih berpotensi dalam mencegah kasus diabetes mellitus dibandingkan dengan ekstrak sambiloto sokhletasi.
Keyword: diabetes mellitus, ekstak sambiloto, ginjal, testis

Judul: Construction of Strongly Optimal Binary Linear Code with Minimum Distance 9 and 11
Abstrak: A binary linear code of length n over q F is a subspace of n q F . A code has three parameters that attached to it, namely length, dimension, and minimum distance. A code with length n, dimension k and minimum distance d is often called [n, k, d ]-code. Usually, when two parameters are given, then we want to find a code that has the best value for the last parameter. Based on Gilbert- Varshamov bound, if a [n, k, d ]-code exists and can not be expanded, we call it a strongly optimal code. In this paper, we construct strongly optimal code with minimum distance 9 and 11. In constructing the code, we created a theorem and algorithm based on Gilbert-Varshamov bound before we implement the algorithm to MAPLE programming language. Because of computational limitations, the program can only construct up to k = 10 for d = 9 and k = 12 for d = 11.
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