Judul: Redesain Taman Malabar sebagai Taman Terapi di Kota Bogor.
Abstrak: Taman lingkungan adalah lahan terbuka yang berfungsi sosial dan estetik sebagai sarana kegiatan rekreatif, edukasi atau kegiatan lain pada tingkat lingkungan. Ruang terbuka hijau yang bermanfaat mengurangi stres dikenal sebagai healing garden. Healing garden memberikan ketenangan, keteduhan, dan meremajakan kondisi mental. Konsep healing garden bertujuan untuk meningkatkan kemampuan penyembuhan dengan melihat keindahan alam taman dan juga suasana yang alami. Umumnya, Healing garden merupakan taman rumah sakit yang diperuntukkan bagi pasien, namun kini healing garden dapat dinikmati masyarakat umum. Taman dengan konsep kesehatan sangat dibutuhkan di kota Bogor sebagai wadah untuk mempercepat penyembuhan dari penyakit terkait psikologis. Taman Malabar yang berdekatan dengan Rumah Sakit PMI dan Plaza Pangrango yang direncanakan menjadi Rumah Sakit Siloam menjadikan lokasi yang tepat untuk menjadikannya sebagai healing garden. Tujuan dari penelitian ini adalah untuk menganalisis hasil preferensi dan kebutuhan masyarakat terhadap healing garden. Menganalisis kegiatan yang ada dengan memperhitungkan daya dukung tapak merupakan dasar utama dalam merancang taman sebagai healing garden. Sintesis berupa rekomendasi kriteria healing garden beserta elemen desain yang harus diaplikasikan pada tapak berdasarkan hasil analisis. Output dari penelitian ini berupa site plan yang menampilkan desain yang membagi ruang berdasarkan kebutuhan aktivitas. Site plan ini juga dilengkapi dengan gambar-gambar detil seperti potongan tampak, gambar perspektif dan detil desain.
Keyword: Healing garden, kebutuhan taman, taman lingkungan

Judul: Perancangan Ulang Taman Rumah Sakit sebagai Healing Garden
Abstrak: Healing garden is one type of green open spaces that has significant roles in relieving stress in the hope to accelerate patient’s healing process. Thus healing garden will be suitable to be applied in hospital’s garden. The problem is many hospitals don’t provide healing garden as their facility despite having a potential garden, like Darmo Hospital and Jemursari Islamic Hospital in Surabaya. The objectives of this research are analyzing people preferences about hospital garden regarding healing garden in general and using the preferences as a primary foundation and literature studies as supporting data to redesign each of the hospital’s garden. The result of the collected data through observation and interview method show that not only patients but also medical personnel agreed to add a healing garden as a support facility in their hospitals. This research resulted two healing garden designs for each hospitals. Both designs fulfill all the criteria, users’ preferences and needs, and also match with the characteristics of both hospitals.
Keyword: hospital garden, healing garden, garden preferences

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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