Judul: Evaluation of Urban Landscape Comfort with Amenity Index Approach in Tangerang City
Abstrak: Laju kepadatan penduduk Kota Tangerang mengalami kenaikan yang cukup signifikan setiap tahunnya. Fenomena tersebut meningkatkan pembangunan kota yang dapat mengganggu keseimbangan lingkungan dan berdampak buruk pada kenyamanan lanskap. Tujuan penelitian ini adalah menganalisis persepsi masyarakat dan mengevaluasi kenyamanan lanskap berdasarkan Urban Landscape Quality Index (ULQI), melakukan pemetaan kenyamanan dan menyusun rekomendasi untuk meningkatkan kenyamanan lanskap Kota Tangerang. Metode yang digunakan dalam penelitian ini adalah metode ULQI. Analisis persepsi masyarakat mengacu pada survei pengisian kuisioner dan menghitung nilai ULQI mengacu pada penilaian visual elemen lanskap. Berdasarkan evaluasi di enam kecamatan, lanskap Kota Tangerang tergolong baik dengan nilai analisis sebesar 75,5 dan nilai ULQI sebesar 2,65. Pemetaan tingkat kenyamanan lanskap mengalami perbedaan dengan tingkat akurasi sebesar 60%. Rekomendasi yang diajukan terfokus pada Batuceper dan Larangan sebagai kecamatan dengan nilai terendah. Usulan berupa peningkatan kuantitas dan kualitas Ruang Terbuka Hijau, taman bermain, jalur sepeda, trotoar, tempat pengelolaan limbah, lapangan olahraga, dan ruang parkir., The population density rate of Tangerang City has increased significantly every year. This phenomenon increases urban development which can disrupt the environmental balance and adversely affect the comfort of the landscape. The purpose of this study was to analyze public perceptions and evaluate the comfort of the landscape based on the Urban Landscape Quality Index (ULQI), to map the comfort and to develop recommendations to improve the comfort of the Tangerang City landscape. The method used in this study is the ULQI method. The analysis of public perceptions refers to the survey filling out the questionnaire and calculating the ULQI score refers to the visual assessment of landscape elements. Based on the evaluation in six sub districts, the Tangerang City landscape is classified as good with an analysis value of 72,7 and a ULQI value of 2,7. Mapping the comfort level of the landscape is difference with an accuracy rate of 60%. Recommendations focus on Batuceper and Larangan as the sub districts with the lowest score, in the form of increasing the quantity and quality of green open spaces, playgrounds, bicycle lanes, sidewalks, waste management areas, sports fields, and parking spaces.
Keyword: Element, Comfort, Urban landscape, Development

Judul: EVALUATION OF GREEN CITY ON GREEN OPEN SPACE IN TANGERANG CITY
Abstrak: Kota Tangerang merupakan sebuah wilayah di Provinsi Banten yang mengalami perubahan penggunaan lahan karena meningkatnya angka jumlah penduduk. Di Tengah permasalahan tersebut, kota hijau hadir sebagai konsep pengembangan kota yang berkelanjutan. Sejalan dengan perkembangan di Kota Tangerang, upaya pemerintah dalam mewujudkan kota hijau perlu dianalisis untuk mengetahui kinerja kota. Tujuan utama penelitian ini adalah mengevaluasi penerapan konsep kota hijau di Kota Tangerang. Secara makro, evaluasi dilakukan dengan menganalisis perubahan tutupan lahan menggunakan penginderaan jauh. Secara mikro, kualitas ruang terbuka hijau juga dianalisis dengan mengidentifikasi RTH Publik terpilih berdasarkan kriteria 8 atribut kota hijau. Hasil penelitian menunjukkan bahwa kawasan terbuka hijau di Kota Tangerang terus mengalami penurunan dari tahun 2009 sebesar 38,29%, lalu pada tahun 2016 sebesar 28,07%, hingga tahun 2023 sebesar 21,84%. Di sisi lain, persentase penerapan atribut kota hijau pada Alun-alun Cibodas dan Hutan Kota Tangerang berurutan sebesar 48,30% dan 57,28% menandakan kualitas kedua RTH tersebut masih kurang baik. Selain menjaga RTH eksisting dan melakukan revitalisasi pada lahan kosong, pemerintah juga harus memperhatikan kualitas RTH yang ada agar dapat meningkatkan kelestarian lingkungan dan kualitas hidup di Kota Tangerang., Tangerang City is an area in Banten Province that is experiencing land use change due to the increasing population. In the midst of these problems, green city has emerged as a concept of sustainable urban development. In line with the development of Tangerang City, the government's efforts in realizing a green city need to be analyzed to determine the city's performance. The main objective of this study is to evaluate the implementation of the green city concept in Tangerang City. At a macro level, the evaluation is conducted by analyzing land cover change using remote sensing. On a micro level, the quality of green open space was also analyzed by identifying selected public green spaces based on the criteria of 8 green city attributes. The results showed that the green open space area in Tangerang City continued to decline from 2009 by 38.29%, then in 2016 by 28.07%, to 2023 by 21.84%. On the other hand, the percentage of implementation of green city attributes in Alun-alun Cibodas and Hutan Kota Tangerang is 48.30% and 57.28% respectively, indicating that the quality of the two green spaces is still poor. In addition to maintaining existing green spaces and revitalizing vacant land, the government must also pay attention to the quality of existing green spaces in order to improve environmental sustainability and quality of life in Tangerang City.
Keyword: Remote sensing, green city, green open space, land cover change

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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