Judul: Sitotoksisitas Fraksi Aktif Biji Mahoni (Swietenia mahagoni) pada Sel Kanker Payudara T47D
Abstrak: Ethyl asetate fraction was reported to be toxic to Artemia salina and has a potency as medicine. The purpose of this study was to examine cytotoxicity of active fraction from Swietenia mahagoni seed toward breast cancer T47D. Ethyl acetate fraction was fractionated used clasic cromatography coloum with silica gel as the stationary phase and chloroform-ethyl acetate as the mobile phase gradiently and yielded 8 fraction. Fraction 2 with 50 lethal concentration 74.30 ppm could inhibit the growth of T47D cell with 50 inhibition concentration of 49.12 ppm. Based on phytocemical assay, fraction 2 consisted of alkaloid and steroid/triterpenoid.
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Judul: Sitotoksisitas Fraksi Teraktif Biji Mahoni Berdaun Lebar (Swietenia macrophylla) terhadap Sel Kanker MCF-7
Abstrak: Tanaman mahoni (Swietenia macrophylla) memiliki aktivitas antikanker, terutama pada bagian biji. Penelitian ini bertujuan mendapatkan fraksi paling toksik terhadap larva Artemia salina pada biji mahoni, menentukan sitotoksisitasnya terhadap sel kanker payudara MCF-7, dan mengidentifikasi senyawa dugaan menggunakan liquid chromatography-mass spectrometry. Sampel dikeringudarakan dan digiling, kemudian diekstraksi dan menghasilkan ekstrak etil asetat yang mengandung golongan senyawa triterpenoid yang berperan sebagai antikanker. Ekstrak etil asetat selanjutnya difraksionasi menggunakan kromatografi cair vakum yang menghasilkan 10 fraksi. Fraksi ke-7 paling toksik terhadap A. salina dengan LC50 43.94 μg/mL. Fraksionasi kembali pada fraksi 7 menghasilkan 3 fraksi teraktif, yaitu fraksi 7a, 7b dan 7i dengan nilai LC50 berturut-turut sebesar 23.55, 34.14, dan 19.93 μg/mL. Hasil ini menunjukkan bahwa fraksi teraktif berpotensi sebagai antikanker. Fraksi 7b dengan rendemen 5.93% menunjukkan sitotoksisitas terhadap sel MCF-7 dengan persen inhibisi sebesar 76.49% pada konsentrasi 50 μg/mL. Profil kromatogram fraksi 7b diduga menunjukkan adanya golongan senyawa limonoid yang diduga berperan dalam antikanker.
Keyword: fraksionasi, sitotoksisitas, Swietenia macrophylla, toksisitas

Judul: Model Ekonomi Kecil Australia dengan Metode VAR
Abstrak: The objective of this research is to build an Australian small economic model that use Australian Gross Domestic Product (PDB), Consumer Price Index (IHK), and the Central Bank Interest Rate (SBB) data in the period of 1991 (1) - 2013 (4). The small economic model formed in this research was the two order Vector Error Correction Model (VECM) with one cointegration rank. There is a positive association between PDB with IHK and SBB with IHK and a negative association between SBB and PDB. There is only one partial equation between IHK with the lag effect of PDB and SBB. IHK partial equation can explain the influence of monetary policy by the establishment of SBB from Australian government to change IHK. The response of IHK is very small and not too significant because the Australian economic growth is very stable and the response of PDB can not be analyzed because the partial model of PDB has no effected on the lag of SBB.
Keyword: Bogor Agricultural University (IPB), VECM, VAR, Australian small economic model