Judul: Toksisitas Ekstrak Etanol Temu Lawak (Curcuma xanthorriza Roxb) Berdasarkan Uji Letalitas Larva Udang dan Embrio Ikan Zebra
Abstrak: Temu lawak (Curcuma xanthorriza) telah diketahui memiliki berbagai aktivitas farmakologis dengan kurkuminoid adalah senyawa aktif yang dominan. Penelitian ini bertujuan menentukan kadar kurkuminoid dan menguji toksisitas ekstrak etanol dan fraksi etil asetat temu lawak. Kadar kurkuminoid ditentukan menggunakan kromatografi cair kinerja tinggi, sedangkan uji toksisitas menggunakan larva udang (metode BSLT) dan embrio ikan zebra (metode ZFET). Berdasarkan hasil penelitian, kadar kurkuminoid ekstrak etanol lebih tinggi daripada fraksi etil asetat, yaitu 105 mg/g. Hasil uji toksisitas menunjukkan nilai konsentrasi mematikan 50% (LC50) pada metode ZFET lebih kecil daripada metode BSLT. Pada metode BSLT, nilai LC50 ekstrak etanol adalah 238 ppm dan fraksi etil asetat 177 ppm, sedangkan pada metode ZFET, nilai LC50 96 jam pascafertilisasi ekstrak etanol adalah 80 ppm dan fraksi etil asetat 94 ppm. Ekstrak etanol menyebabkan malformasi mayor pada jantung, sedangkan pemberian fraksi etil asetat menyebabkan malformasi mayor pada sumbu tubuh dan jantung embrio ikan zebra.
Keyword: BSLT, LC50, temu lawak, toksisitas, ZFET

Judul: Uji Toksisitas Ekstrak Etanol Rimpang Temu Putih terhadap Larva Udang dan Embrio Ikan Zebra
Abstrak: Curcuma zedoaria, known as temu putih, is commonly used as traditional medicine in Indonesia. The toxicity of this herb needs to be studied to improve its application. This research aims to evaluate the toxicity of the crude ethanol extract of temu putih rhizome against brine shrimp (Artemia salina) larvae and zebrafish (Danio rerio) embryos and to analyze the suspected active compounds contained in the extract. The crude ethanol extract showed 50% lethal concentration value (LC50) at 588 ppm against brine shrimp larvae and 215 ppm against zebrafish embryos. In zebrafish embryos, exposure of the crude ethanol extract has caused major malformation in development of head, namely brain and eyes organs. Based on the gas chromatography-mass spectrometry analysis, the suspected active compound that play a role in the toxicity are epicurzerenone, curzerene, and curzerenone, which 2,4,6-trimethylacetophenone as the predominant compound.
Keyword: Bogor Agricultural University (IPB), LC50, Danio rerio, Curcuma zedoaria, Artemia salina

Judul: Pengembangan Sistem Rotasi Peta pada Perangkat Mobile tanpa Sensor Magnetometer
Abstrak: Due to the improvement of technology, the function of mobile phone has changed a lot. Nowadays, mobile phone is used not only for communication, but also to support the user’s activity. Many mobile phones now have Operating System (OS) and sensors like GPS and magnetometer. GPS is a sensor that can be used to identify any location, including the location of the user, while magnetometer can be used to identify direction. With data that come from GPS and magnetometer, we can build a navigation application that can rotate its map according to the rotation of the user. Meanwhile, in the Android Compability Definition Document point 1.6 until 2.2, Google have requirements for mobile phones to have GPS and magnetometer sensors if they want to use Android OS. But, since the release of 2.3.3 OS, Google has changed its requirements, allowing any mobile phones to have Android OS without having the magnetometer sensor. The objective of this research is to build an navigation application that can rotate without using magnetometer sensor. The value of the rotation degree is taken from last two position. To stabilize the value, Exponential Smoothing is used in filtering process. This system also use Haversine method to recognize whether the user is walking or driving/riding.
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