Judul: Analisis Siklon Tropis Narelle 2013 Menggunakan Model WRF
Abstrak: Narelle is a tropical cyclone which started on January 8 and decayed on January 14 2013 and took place in the Southern Hindia Ocean near the Nusa Tenggara Timur to the west of Australian coasts. The objective of this research is to analyze the relationship of surface heat flux with a cyclones Narelle 2013. The strength of relationship between surface heat flux and Narelle cyclone parameter is evaluated using a correlation coefficient. WRF model is, then, utilized to generate meteorological parameters which are responsible in the formation of the cyclone at its earliest stage. The parameters include pressure, surface sensible heat flux, surface latent heat flux, wind speed and SST. The result shows that surface latent heat flux is related to SST in the formation of Narelle cyclone with correlation coefficient of 0.89 and surface sensible heat flux is related to the wind speed with a correlation coefficient of 0.88
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Judul: Prediksi Cuaca Jangka Pendek Menggunakan Weather Research and Forecasting (WRF) Model
Abstrak: Short-range forecasting model has become an important tool to describe the complex atmospheric condition. The purpose of this research is to assess the potential of WRF output in short-range forecast. Weather forecasting method utilized in this research is WRF. Outputs of WRF model is compared with observational data of Ngurah Rai, Bali station. Solver in Microsoft Excel is used to reduce error generated in the model. This study focuses on only four output variables of WRF, namely, rainfall (CH), wind, relative humidity (RH) and temperature. The result shows rainfall and temperature are resulting from model calculation are better than the wind and relative humidity. Rainfall variable has an RMSE value of 0.84 and correlation of 0.62 while the RMSE value of the temperature is 1.09 with a correlation of 0.65. Correction process with the help of the Solver is effective in reducing the error of the following variables: temperature by 16%, wind by 62%, RH by 35% and rainfall by 87%.
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Judul: Studi Penambatan Molekul Mutan Glukosa Oksidase IPBCC.08.610 untuk Meningkatkan Produksi Asam Glukonat
Abstrak: Glukosa oksidase (GOD) merupakan enzim oksidoreduktase yang mengkatalisis reaksi oksidasi glukosa menjadi β-D-glukono-1,5-lakton dan hidrogen peroksida. Kemudian, β-D-glukono-1,5-lakton akan terhidrolisis menjadi asam glukonat. Penerapan yang luas dari asam glukonat dalam berbagai industri menyebabkan meningkatnya permintaan produksi. Namun, konsentrasi glukosa yang lebih tinggi dari 40% (b/b) menghambat konversi glukosa menjadi asam glukonat karena penurunan konsentrasi kelarutan oksigen. Oleh karena itu, penurunan nilai Km diharapkan dapat menurunkan kejenuhan serta meningkatkan produksi asam glukonat. Penelitian ini bertujuan menganalisis interaksi antara mutan glukosa oksidase IPBCC.08.610 dengan β-D-Glukosa dalam meningkatkan produksi asam glukonat dengan menurunkan nilai Km. Mutasi dilakukan secara in silico dengan Chimera lalu dilakukan penambatan dengan AutoDockTools. Mutasi menyebabkan perbedaan pose ligan pada binding pocket, perbedaan konformasi -OH pada ligan, perbedaan indeks hidrofobisitas mutan T554M/D578P, serta penurunan nilai ΔG serta nilai Km pada mutan H559D, D578P serta T554M/D578P. Penurunan tersebut dapat meningkatkan kekuatan interaksi ligan-reseptor sehingga dapat meningkatkan produksi asam glukonat. H559D menjadi mutan terbaik yang dapat meningkatkan produksi tersebut berdasarkan nilai ΔG, nilai Km serta peningkatan kestabilan akibat penambahan ikatan hidrogen. Kata kunci: asam glukonat, glukosa oksidase, mutasi, penambatan molekul
Keyword: Glukosa Oksidase IPBCC.08.610, Asam glukonat, Penambatan molekul, Mutasi, Molecular Docking