Judul: Proses Peroksida Lipid Kelinci Hiperlipidemia pada Pemberian Senyawa Penurun Kolesterol
Abstrak: Radikal bebas banyak mendapat perhatian akhir-akhir i11i karena dianggap memiliki peran yang cukup signifikan dalam tejadinya berbagai penyakit degeneratif. Hiperlipidemia adalah salah satu faktor resiko utama dari aterosklerosis yang mengarah pada penyakit degeneratif tersebut. Penelitian ini bertujuan mengukur konsentrasi lipid peroksida pada darah kelinci yang hiperlipidemia dan pengaruh senyawa penurun kolesterol terhadap konsentrasi lipid peroksidanya. Sebanyak 20 ekor kelinci jantan galur New Zealand white dibagi menjadi empat kelompok percobaan, yaitu kelompok normal yang hanya diberi pakan standar, hiperlipidemia yang diberi pakan aterogenik (kolesterol 0.5% dan minyak kelapa 5%), lovastatin yang diberi campuran pakan aterogenik dan lovastatin (57 mglhari), dan ekstrak yang diberi campuran pakan aterogenik dan ekstrak ramuan daun jati belanda.
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Judul: Proses peroksidasi lipid kelinci yang hiperlipidemia pada pemberian senyawa penurun kolesterol
Abstrak: Radikal bebas banyak mendapat perhatian akhir-akhir ini karena dianggap memiliki peran yang cukup signifikan dalam terjadinya berbagai penyakit degeneratif. Hiperlipidemia adalah salah satu faktor resiko aterosklerosis yang mengarah pada penyakit degeneratif tersebut. Penelitian ini bertujuan mengukur konsentrasi lipid peroksida pada darah kelinci yang hiperlipidemia dan pengaruh senyawa penurun kolesterol terhadap konsentrasi lipid peroksidanya. Sebanyak 20 ekor kelinci jantan galur New Zealand white dibagi menjadi empat kelompok percobaan, yaitu kelompok normal yang hanya diberi pakan standar, hiperlipidemia yang diberi pakan aterogenik (kolesterol 0.5% dan minyak kelapa 5%), lovastatin yang diberi campuran pakan aterogenik dan lovastatin (57 mg/hari), dan ekstrak yang diberi campuran pakan aterogenik dan ekstrak ramuan daun jati belanda. Analisis lipid peroksida darah menggunakan metode tiobarbiturat (Yagi 1994) yang mengukur senyawa malonaldialdehida (MDA) menggunakan spektrofotometer pada λ = 532 nm. Hasil percobaan menunjukkan pemberian pakan aterogenik pada kelinci menyebabkan peningkatan konsentrasi MDA, yang berarti meningkatnya proses peroksidasi lipid dalam tubuh. Kelompok hiperlipidemia mengalami peningkatan konsentrasi lípid peroksida darah sebesar 163.76% bila dibandingkan kelompok normal (1.30 ± 0.38 nmol/ml). Lovastatin dan ekstrak ramuan daun jati belanda dapat berperan sebagai antioksidan dengan cara menurunkan konsentrasi lipid peroksida darah sebesar 46.92% dan 53.03% berturut-turut pada minggu ke-8 perlakuan dibandingkan kelompok hiperlipidemia.
Keyword: Peroksidasi, Lipid, Kelinci

Judul: Characteristic of Overshooting Top (OT) Based on  Himawari  8  Satellite  as  a  Convective  Cloud  Feature  that  Generates  Extreme Weather in the Java Island Region
Abstrak: Overshooting Top (OT) is a feature at the top of a convective cloud that is associated with extreme weather. Research on OT in tropical Indonesia is still very limited. The existence of geostationary satellites with wide area coverage and fast frequency observations is useful for observing the fast dynamics of the OT life cycle. Therefore, this study intends to analyze the relationship between OT and extreme weather, updraft and thermodynamic conditions of OT when extreme weather occurs, the best objective method for detecting OT in the day time and night time, and the spatiotemporal distribution of OT in the tropical region of Java Island during the 2018-2021 period. Based on visual analysis using visible channel and Himawari 8 sandwich products, 87% of extreme weather events in Java were accompanied by the appearance of OT. It indicates that the presence of the OT pattern is a convection cloud pattern or feature that is closely related to extreme weather events for the Java Island region. The existence of a time lag between the appearance of OT and extreme weather events on Java Island indicates that the OT of convection cloud can be used as a precursor or nowcasting for the appearance of extreme weather. Most of the convective cloud OT features during extreme weather events on Java Island have altitude that were only able to exceed the altitude of the equilibrium level and few were able to exceed the tropopause level of 9 km – 16 km. The difference in atmospheric conditions during extreme weather events on Java Island, which is in the tropics and subtropics, is a strong and unstable convective energy condition characterized by a larger CAPE, as well as unstable KI, LI, SI and TTI values. It is offset by kinematic factors in the form of a weak vertical wind shear (bulk wind shear 0-6 km) and a higher freezing point height. The difference between extreme weather events in the Java Island region and other tropical regions compared to subtropical regions is the strong updraft speed of convection clouds. The IRW Texture COMB algorithm based on the IRW-Texture Gradient modification and the COMB algorithm shows a significant increase in quality for detecting OT and non-OT pixels in Java. Rainy days with rainfall > 50 mm/day are very common in areas with an altitude of > 500 m. On the other hand, the level of convection activity which is indicated by the presence of OT and lightning is significantly reduced in this area. OT of convective clouds appear more frequently during the DJF season and less frequently during the JJA season. OT often appears during the day time and rarely at night time. Most OTs appear in the central part, away from the south and north coasts of Java Island during the day, while OTs that appear near the south and north coasts of Java Island can appear in the morning or afternoon.
Keyword: convective clouds, extreme weather, Overshooting Tops, Himawari 8 Satellite