Judul: Kelembagaan Lokal : Bentuk Adaptasi Sosio-Ekologi Daerah Rawan Longsor (Kasus Kampung Sirnagalih, Desa Sukaraksa, Kabupaten Bogor, Provinsi Jawa Barat).
Abstrak: Landslides have damaged the cultivated land, settlements, and other infrastructures. Such damages have led the people to make adaptation as a survival strategy. The objective of this study are to describe and analyze: (1) the reality of landslides, (2) the people perceptions of both environment and their ability as well as self-confidence (3) the shapes of socio-ecological adaptation landslide-prone, and (4) the local institutions of landslides areas. The location of this study in Sirnagalih Kampong, Sukaraksa Village, Bogor Regency, West Java. The study used a combination of two techniques of data collection: a quantitative technique to measure perception, and a qualitative technique to explore the reality of landslides, the forms of socio-ecological adaptation and the local institutions of landslide communities. The result of this study reveals that the reality of landslides-prones have changed the people perceptions about environment, and pushed the shapes of socio-ecological adaptation. Further, the shape of adaptation is followed by the norms to manage and use the natural resources. Besides, the shapes of adaptation affect the availability of local institutions in landslide-prones communities.
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Judul: Vulnerability and Community Resilience in Facing Landslide Disaster (Case: Kampung Muara 1, Cibunian Village, Pamijahan District, Bogor Regency, West Java)
Abstrak: Bencana tanah longsor merupakan suatu peristiwa alam yang dapat menyebabkan kerugian di berbagai aspek bagi komunitas yang terdampak. Dampak kerugian dari terjadinya bencana tersebut memungkinkan adanya perubahan pada tingkat kerentanan dari suatu komunitas. Salah satu cara menanggulangi kerentanan komunitas tersebut adalah dengan meningkatkan kapasitas adaptif yang dimiliki oleh komunitas terdampak sehingga komunitas akan lebih mudah dalam mencapai tahap resiliensi. Penelitian ini memiliki tujuan untuk menganalisis tingkatan dan hubungan antara kerentanan dan resiliensi komunitas dalam menghadapi bencana tanah longsor. Pendekatan yang dilakukan pada penelitian ini adalah pendekatan kuantitatif dengan metode survei kepada 80 orang responden, kemudian didukung dengan pendekatan kualitatif yang menggunakan metode wawancara mendalam. Hasil penelitian menunjukkan bahwa tingkat kerentanan dan tingkat resiliensi dari komunitas Kampung Muara 1 tergolong sedang, serta terdapat hubungan antara tingkat kerentanan dan tingkat resiliensi komunitas tersebut., A landslide disaster is a natural event that can cause losses in various aspects for the affected community. The impact of losses from these disasters allows for changes in the level of vulnerability of a community. One way to overcome community vulnerability is to increase the adaptive capacity of affected communities so that it will be easier for the community to reach the resilience stage. This research aims to analyze the level and relationship between community vulnerability and resilience in facing landslide disasters. The approach taken in this research was a quantitative approach using a survey method for 80 respondents, then supported by a qualitative approach using in-depth interview methods. The research results show that the level of vulnerability and level of resilience of the Muara 1 Village community is classified as moderate, and there is a relationship between the level of vulnerability and the level of resilience of the community.
Keyword: community resilience, lanslide disaster, vulnerability, adaptive capacity

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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