Judul: Upaya Isolasi Drakorodin dari Resin Daemonorops draco
Abstrak: Dragon’s blood is a secretion of rattan fruits. The commonly used rattan species is Daemonorops draco that contain the highest dracorhodin, but the content has not been determined quantitatively. Dracorhodin is a natural flavylium compound, anthocyanin derivative, and provides the natural color of dragon’s blood. This compound is potential as drug materials and natural dye. Dracorhodin isolated from dragon’s blood crude extract were analyzed using ultraviolet-visible (UV-Vis) spectrophotometric and high performance liquid chromatography (HPLC) with C18 column (5 μm, 250 × 4.6 mm id, Dikma). The samples were treated in acidic (60% HClO4) and non-acidic medium. UV-Vis spectra showed that dracorhodin was also detected at 400—490 nm. Dracorhodin was detected in HPLC chromatogram at retention time of 5 minutes, using ethyl acetate 1% in methanol as eluent, 0.5 mL/min flow rate, and detection wavelength at 475 nm. Dracorhodin content obtained from non-acidic medium crude methanol extract was 55.6%, which was higher than that in the acidic medium, namely 37.4% from the starting materials that was refluxed for about 1 hour. The isolates can be used as standard for quantifying dracorhodin in commercial dragon’s blood.
Keyword: high performance liquid chromatography, flavylium, dragon’s blood, dracorhodin, Daemonorops draco

Judul: Potensi Antikanker dan Identifikasi Fraksi Drakorodin Jernang Daemonorops draco
Abstrak: Dragon’s blood Daemonorops sp. has been used as traditional medicines and natural dyes. However, dragon’s bloods of Dracaena sp. and Croton sp. are well-known to have many pharmacological activities in some other countries, including anticancer. This research aimed to determine the toxicity of the extract related to its potential as anticancer and to determine dracorhodin fraction as the main anthocyanin compound in dragon’s blood. The experiment involved extraction, partition, fractionation, and brine shrimp lethality test. The LC50 value of methanol and ethyl acetate extracts were 70 and 570 ppm, respectively. Fractionation of the methanol extract by using column chromatography with gradient elution with n-hexane and ethyl acetate provided 6 fractions. Ultraviolet-visible spectrum of the fraction 6 showed a maximum absorbance at 467 nm, lying in the range of anthocyanin maximum wavelength. Identification by using gas chromatograph-mass spectrometer proved that the presumed dracorhodin existed in this fraction, at 22.45 minutes retention time and with 4.30% abundance.
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Judul: Peranan Kepemimpinan Desa dalam Perubahan Struktural Masyarakat Pedesaan
Abstrak: Aspek aspek pokok perrnasalahan penelitian ,meliputi:(1) Pengaruh peranan kepeniimpinan Kepaia Oesa terhadap peranan kepemimpinan pemimpin masyarakat dan pengaruh peranan lcepemimpinan masyarakat terhadap perubahan peranan anggota masyaraltat dalam berbagai aspek kelembagaan serta perubahan status sosial ekonomi anggota masyarakat , (2)Peranan managerial Kepala Desa dan aktivitas peranan pemimpin masyarakat, jarak sosial dan illt egrasisosial Kepa1,a Desa dengan p~amimpin masyaraltat dan pemimpin masyaraltat dengan ailggota masyarakat , (3)Pengaruh faktor kondisi masyarakat; faktor ekstern desa dan kemampuan individual (peribadi) masing masing terhadap peranan kepemimpinan Kepala Desa, terhadap peranan ltepemimpinan pemirnpin masyarakat dan terhada perubahan peranan dan perubahan status sosial ekonomi anggota masyarakat .
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