Judul: Desain Lanskap Agrowisata Tamansari Berbasis Kearifan Lokal Budaya Sunda di Kabupaten Bogor
Abstrak: Economic development is coherent with industrialization in the cities. It also decrease social values and local culture indirectly. One effort to solve this problems is to conserve agriculture and local wisdom itself. Agrotourism is one of tourism type which use agriculture as its object. Tamansari site, Bogor, has potencies to become agrotourism because of authentic agroecosystem and suitable soil for agriculture. This research is purposed to design agrotourism based on Sundanese local wisdom. The methods is spatial analysis to process physical and biophysical data, quantitative analysis to quantify Carrying Capacity, Thermal Humidity Index (THI), and Agrotourism Area Feasibility Assignment, and also descriptive analysis to know user preferences. The synthesis is agrotourism development area and Opat Kalima Pancer concept design implementation. This research output is design drawing (siteplan) completed with detail drawings (section plan, perspective drawing, and planting plan).
Keyword: Bogor Agricultural University (IPB), Sundanese Culture, Local Wisdom, Agrotourism, Landscape Design

Judul: Studi Potensi Lanskap Perdesaan Untuk Pengembangan Agrowisata Berbasis Masyarakat Di Kecamatan Tamansari Kabupaten Bogor.
Abstrak: Banyak lahan pertanian yang dialihfungsikan, terutama untuk lahan industri dan kawasan permukiman. Lahan pertanian dinilai kurang menguntungkan secara ekonomi, padahal merupakan aspek penting bagi Indonesia sebagai negara agraris. Lahan pertanian membutuhkan nilai tambah untuk mempertahankan eksistensinya. Hal tersebut dapat dicapai dengan agrowisata melalui jasa wisata dan pemasaran produk pertanian yang lebih baik. Studi ini dilaksanakan di Kecamatan Tamansari Kabupaten Bogor. Studi ini menganalisis aspek fisik-biofisik, aspek sosial-budaya, aspek wisata, dan aspek legal dengan menggunakan tiga metode analisis, yaitu analisis kesesuaian dan kelayakan agrowisata, analisis persepsi dan preferensi, dan analisis penilaian keberlanjutan masyarakat. Studi ini menemukan empat belas potensi atraksi wisata dengan tujuh diantaranya berpotensi untuk agrowisata. Studi ini juga menunjukkan bahwa desa yang sangat berpotensi untuk agrowisata adalah Desa Pasir Eurih dan Desa Tamansari, sementara Desa Sukaluyu dan Desa Sukajadi berpotensi untuk agrowisata. Dalam penilaian keberlanjutan masyarakat, keempat desa tersebut telah menunjukkan awal yang baik menuju keberlanjutan. Pasir Eurih memiliki skor tertinggi, diikuti oleh Sukaluyu, Tamansari, dan Sukajadi secara berurutan. Direkomendasikan untuk mengembangkan agrowisata berbasis masyarakat di Desa Pasir Eurih.
Keyword: agrowisata, agrowisata berbasis masyarakat, lanskap perdesaan, nilai tambah pertanian, potensi agrowisata

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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