Judul: Pola Pertumbuhan Pria Usia 4 sampai 21 Tahun di Suku Baduy, Desa Kanekes, Kecamatan Leuwidamar, Kabupaten Lebak, Banten
Abstrak: Growth is an increasing process of body size that follow a predictable pattern. Body size can be determined by calculating the Body Mass Index (BMI), which is the ratio of weight (kg) and the square of statures (m2). The growth pattern can be determined by connecting the median of each class of age. The research purpose was to find the body size growth pattern of male aged 4 to 21 years old in Suku Baduy. Even so, the growth velocity curve start at the same time, the statures growth velocity curve reach the peak first, then so do latter the weight growth velocity curve. The peak of BMI growth velocity curve happened in the age of 13 years old with the growth velocity was 0.804 kg/m2 per year. Based on the BMI value, the body size of male in Suku Baduy was small. This thing was happened due to the high level of physical activities.
Keyword: 

Judul: Lintasan Pertumbuhan dari Ukuran Tubuh Orang Baduy
Abstrak: The measurenment of body size is the best way to find out the health, nutritional status and quality of life of a population. Many indigenous populations that are local, scattered, and less or not involved in the network of social services, economic and politics, have specific growth trajectories. Baduy people are indigenous population which is more-or-less socially isolated. Marriage is restricted among Baduy people only. Present study aims to determine the growth trajectory of female and male of Baduy people with cross-sectional method. Body size of Baduy people may be categorized as same size as pygmy population. They have a slow growth rate at child to juvenile transition, low and long growth spurt with prolonged growth well beyond reproductive maturation. Low growth spurt, which leads to small body size in the growing period, may be a saving on body maintenance costs. Prolonged somatic growth offset the slow growth rate at child to juvenile transition and low growth spurt. Baduy people older than 30 year are shorter and smaller than younger people, suggesting secular trend.
Keyword: 

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
Keyword: