Judul: Analisis perhitungan harga pokok produksi sepatu dengan metode full costing: studi kasus UKM Galaksi Kampung Kabandungan, Ciapus, Bogor
Abstrak: Pesatnya pembangunan pada dunia industri meningkatkan persaingan yang terjadi antar perusahaan dalam menghasilkan produk-produk berkualitas dengan harga yang cukup bersaing. Sektor Usaha Kecil Menengah (UKM) merupakan salah satu industri yang turut bersaing dalam memajukan perekonomian di Indonesia. UKM Galaksi merupakan usaha skala kecil dan menengah yang memiliki usaha memproduksi sepatu khusus wanita jenis balet. UKM Galaksi memasarkan produknya kepada pihak grosir yang berada di Pasar Grosir Bogor yang terletak di Jalan Sartika Bogor yang selanjutnya akan memasarkan produk sepatu keluar daerah.
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Judul: Analisis perhitungan harga pokok produksi sepatu dengan metode full costing: studi kasus UKM Galaksi Kampung Kabandungan, Ciapus, Bogor
Abstrak: Education was one of the service fields in order to bring about the process pembelajaran so that participants educated actively developed the potential himself to have the spiritual strength of piety, self control, the identity, intelligence, the noble moral, as well as skills that was needed from him, the community, the nation, and the country. Edukatif centres carried out the competitive process with the agency bimbel in the Bogor city by carrying out the exact and superior strategy. The promotion was the strategy that until this became the main priority. EPIC Model and Direct Rating Method were used to evaluate the strength of a promotion that was linked with the promotion capacity to get attention, was easy not him the promotion was read thoroughly, was easy not him the promotion was understood, the promotion capacity to awaken the feeling and this promotion capacity to influence the behaviour.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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