Judul: Pemodelan Stokastik Pertumbuhan Penduduk di Kota Rembang dengan Mempertimbangkan Proses Kelahiran, Kematian, dan Migrasi
Abstrak: The Population growth can be determined using birth and death rates and also the factor of migration. Both birth and death proceses are considered within Poisson process. An increase of population level would decrease the land residence, the number of homes, and the job opportunities. Therefore, we need stochastic models to estimate the population level in the Rembang city, Central Java province. This study is to draw up a stochastic population growth model through birth, death and migration process to predict the level of population. The data are processed using the trend analysis and the merger methods. The result of stochastic modeling shows that the level of population in the city of Rembang in 2013 are 603784, and in the following year was 610895.
Keyword: Bogor Agricultural University (IPB), Poisson process., population growth, stochastic model, trend analysis

Judul: Analysis of stable and quasi-stable population growth models
Abstrak: Model pertumbuhan penduduk merupakan hal yang penting dalam mengantisipasi persoalan ekonomi, social, dan politik dalam suatu bangsa yang diakibatkan oleh perubahan jumlah penduduk. Perubahan jumlah penduduk dapat dipengaruhi oleh faktor fertilitas, mortalitas , dan migrasi. Karya ilmiah ini bertujuan untuk memodelkan pertumbuhan penduduk stabil dan kuasi-stabil lalu mengaplikasikannya dalam penduduk Indonesia tahun 2000, 2005 dan 2010. Hasil proyeksi akan dibandingkan dengan data sensus lalu akan diperoleh nilai galatnya. Hasil penelitian menunjukkan bahwa model kuasi-stabil dengan adanya faktor perbaikan kematian lebih baik daripada model stabil. Berdasarkan model kuasi-stabil hasil proyeksi penduduk Indonesia tahun 2015 sebesar 255,236,560. Keywords : pertumbuhan penduduk, kuasi-stabil, fertilitas, mortalitas., Model of population growth is essential to anticipate problems in the economic, social and political in a nation that affected by the change of population. Changes in a population can be affected by factors of fertility, mortality, and migration. This paper aims to model stable and quasi-stable population growth and then applies these models to population of Indonesia for 2000, 2005 and 2010. The projection results is compared to the census data and then error value will be obtained. The results showed that the quasi-stable model with mortality improvement factor is better than the stable model. Based on the quasistable model, prediction of population of Indonesia in 2015 is 255,236,560. Keywords: population growth, quasi-stable, fertility, mortality
Keyword: pertumbuhan penduduk, kuasi-stabil, fertilitas, mortalitas

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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