Judul: Dampak Ritel Modern terhadap Omzet Pedagang Pasar Tradisional di Kota Bogor
Abstrak: This study analyzes the factors that influence changes in the turnover of traders in traditional markets, as well as competition, performance and characteristics of merchant traders in Bogor. The methods used in this study were a paired sample t-test and ordinal logistic regression. The results of the ordinal logistic regression showed that the factors that influence changes in a merchant turnover are education, number of buyers, diversification of products, and distance. Another factor affecting of the turnover is the main commodity sold by the traders. Traders selling fresh and processed products have the higher opportunity to increase turnover compared to other commodities traders
Keyword: t-test., competition, ordinal logistic regression, turnover, performance, Bogor Agricultural University (IPB)

Judul: Dampak Kehadiran Ritel Modern terhadap Profitabilitas Pedagang Pasar Tradisional di Kota Bekasi
Abstrak: The aims of this research are to analyze the impact of modern retail on the profitability level of traditional market traders in Bekasi. The market selection is done by purposive sampling method. Jatiasih Market and Family Mart Market are selected as treatment group and Bantargebang Market is selected as control group. The methods using in this study are t-test, chi-square test, and ordinal logistic regression. Factors influencing changes of profit are the number of buyers, the distance between the traditional market with the modern retail, the main commodity of fresh products and processed products. The closer distance the traditional market to the modern retail, the more chance of traditional market traders to increase their profits.
Keyword: t-test, modern retail, traditional markets, ordinal logistic regression, profit, chi-square test

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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