Judul: Perancangan Supply Chain Network untuk Penentuan Lokasi  Produksi dan Jalur Distribusi
Abstrak: Supply chain management merupakan konsep yang mengintegrasikan aliran informasi dari pemasok ke konsumen. Supply chain management terdiri atas beberapa faktor utama di antaranya adalah supply chain network dan informasi. Supply chain network terdiri atas lokasi produksi dan jalur distribusi. Lokasi produksi akan memengaruhi jalur distribusi dan respons terhadap permintaan konsumen. Lokasi yang tidak tepat akan berdampak pada respons terhadap permintaan pasar lebih lama dan jarak yang ditempuh menjadi tidak optimal.
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Judul: Penerapan Metode Heuristik Dalam Supply Chain Network Untuk Menentukan Jalur Distribusi Terpendek
Abstrak: Supply chain management is a process of manufacture and delivery of goods to consumers. One of the main factors of supply chain management is supply chain networks. Supply chain networks consist of two main parts, i.e. , the location of production and the distribution process. Both are related to the determination of optimum distribution channels or routes from producers to consumers which are related to time, distance, and vehicle capacity. This problem is called with the Vehicle Routing Problem with Time Windows (VRPTW). This research work was conducted in the supply chain division of KATRACO CV, a private company that engaged in the distribution of fuel oil to gas stations and several companies in Central Java and surrounding areas. This research aims to design a supply chain network for VRPTW case to minimize the total distance. In this work we used a heuristic method , i.e. , sweep heuristic, saving heuristic, and the nearest depot heuristic as constructing route. We also used 2-opt, relocate, and exchange methods as route improvement methods to determine a better routes. Furthermore, VRPTW problem is solved using ILOG Dispatcher program version 2.1 and ILOG Solver version 4.4, which is run in Microsoft Visual C + + version 6.0.
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Judul: Durability of Specific Immunoglobulin (Ig) Y Againts Influenza and Covid-19 in Sunscreen
Abstrak: The benefit of specific immunoglobulin Y (Ig Y) as an active ingredient in personal care products such as sunscreen has not been properly studied. Our study aims to evaluate the reliability of specific IgY against influenza and the COVID-19 virus in a sample sunscreen product. Specific IgY influenza and COVID-19 viruses were inserted in the sample sunscreen at two concentrations of 0.1% and 0.25%. Three treatments were observed: control (C) sunscreen without IgY, treatment 1 (T1) sunscreen with 0.1% IgY, and treatment 2 (T2) sunscreen with 0.25% IgY. Organoleptic observations were carried out to monitor changes in aroma, color, and texture, and sunscreen sampling was done every week for 6 weeks. The durability of IgY was evaluated using an enzyme-linked immunosorbent assay (ELISA) and a neutralization assay. Organoleptic observation from weeks 1 to 6 showed consistency in its aroma, color, and texture. Enzyme-linked immunosorbent assay and neutralization assay (NA) results of the T1 and T2 groups showed negative results except for sample T1 at week 5, which showed a positive result in the Influenza A ELISA. Based on the results, it seems that IgY concentrations of 0.1% or 0.25% were not optimal. However, this negative result might be due to low concentration of the IgY and the presence of beeswax, which inhibits IgY and causes it to dissolve in distilled water, thus preventing it from being detected in the assay.
Keyword: Immunoglobulin Y, Sunscreen, Influenza, COVID-19, Biological Activity