Judul: Studi Komputasi Komponen Aktif Jamu Antihiperkolesterolemia Melalui Farmakologi Jejaring Dan Penambatan Molekular
Abstrak: Jamu dengan komposisi jati belanda, kumis kucing, mahkota dewa, dan rimpang bangle diprediksi dapat menurunkan kadar kolesterol dalam darah. Penelitian ini bertujuan mengidentifikasi senyawa aktif formulasi jamu serta mekanisme penghambatan melalui pendekatan farmakologi jejaring dan penambatan molekular. Semua data dikumpulkan dalam format Excel yang kemudian divisualisasikan melalui farmakologi jejaring (Cytoscape). Pengamatan hasil jejaring antara protein dan senyawa metabolit sekunder dalam tanaman menunjukkan 9 senyawa aktif. Evaluasi Drug-likeness dengan menggunakan parameter Rule of Five dari Lipinski, didapatkan 3 senyawa aktif potensial yang memiliki sifat farmakokinetik, yaitu metileugenol, epikatekin, dan asam rosmarinat. Hasil penambatan menunjukkan asam rosmarinat dan epikatekin memiliki afinitas lebih baik dibandingkan dengan standar inhibitor target protein sehingga kedua senyawa tersebut memiliki potensi aktivitas sebagai obat antihiperkolesterolemia.
Keyword: antihiperkolesterolemia, farmakologi jejaring, jamu, penambatan molekular

Judul: Profil Kromatografi Lapis Tipis Jamu Antihiperkolesterol dan Aktivitasnya secara In Vivo
Abstrak: Kolesterol dalam jumlah tinggi selain menyebabkan penyempitan dan pengerasan pembuluh darah juga menyebabkan penyakit hiperkolesterolemia. Tujuan penelitian ini ialah menentukan identitas kimia jamu menggunakan teknik kromatografi lapis tipis (KLT) dan menentukan aktivitas jamu sebagai antihiperkolesterol dengan uji in vivo menggunakan tikus yang diinduksi pakan tinggi kolesterol. Jamu antihiperkolesterol yang digunakan terdiri atas jati belanda, kumis kucing, mahkota dewa, dan bangle. Identitas kimia jamu tersebut ditentukan menggunakan KLT. Hasil penelitian menunjukkan jamu yang digunakan dapat menurunkan kadar kolesterol, trigliserida, lipoprotein densitas rendah (LDL), meningkatkan kadar lipoprotein densitas tinggi (HDL), dan tidak memengaruhi aktivitas aspartate transminase (AST) sehingga tidak menimbulkan gangguan hati pada tikus. Efek pemberian jamu formula 2 (yang terdiri atas 4 ekstrak jamu antihiperkolesterol) lebih baik daripada formula 1 (ekstrak jati belanda saja). Kromatogram KLT yang dielusi dengan pelarut kloroform dan etil asetat menunjukkan pemisahan pita yang baik dibandingkan komposisi eluen lainnya
Keyword: analisis sidik jari, jamu antihiperkolesterol, jati belanda, kumis kucing, mahkota dewa, rimpang bangle

Judul: Biology and ecology of the buffalo fly, haematobia exigua de meijere (diptera:muscidae)
Abstrak: The life history of the buffalo fly was observed at room temperature of 27°-29.5°C and at a relative humidity of 48-68 percent. The eggs hatched after 17-22 hours, with an average of 18 hours. First instar larvae measured 1.25 + 0.16 mm long and 0.27 + 0.037 mm wide. reach the second larval stage. It took 6-12 hours to the second instar larvae measured 2.676 +0.187 mm long and 0.353 +0.028 mm wide. The second instar took about 12-24 hours to reach the third larval stage. The third instar measured 6.833 + 0.189 mm long and 0.919 + 0.051 mm wide. It took about 2-3 days for the third instar to become pupae. Duration of the pupal stage was about 5-7 days before the adults emerged. Under laboratory condition, the buffalo fly completed its life cycle in 9.5 to 10.5 days, whereas under field condition it took 9-14 days with an average of 10.5 days. The growth ratio which was based on the measurements of the cephalo-pharyngeal skeleton of each instar was 1.797. The preoviposition period was 8-12 days and mating usually occurred on the 6th or 7th day. The longevity of the male was 29 days, whereas it was 32 days in the female. The range of egg production under laboratory condition was between 20-139 per female fly. The belly and hind legs of the carabao were the most preferred habitat either during cloudy and cool dry or shiny and warm day. When the weather was clear and the carabao was in the shade, the flies tended to be more distributed particularly on the shoulder, dewlap, back and horns. The carabaos had relatively fewer Musca sp. and Stomoxys calcitrans than cattle; never the less carabaos had a higher infestation of buffalo fly than cattle. Oviposition occured either during the day or night but the buffalo flies were more active during the night than in the day time. The effect of various lengths of exposure time of manure in relation to the oviposition was profound. observed, the maximum number of the buffalo flies was occurred when the dung was exposed for 30 minutes. With increasing time of exposure the number and variety of insects also increase. It was evident that Sepsidae and psychodidae were the most dominant insects emerging from the dung. The number of buffalo flies also increased with increasing
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