Judul: Rencana Pengelolaan Lanskap Eco-Art Park di Sentul City, Bogor
Abstrak: In an effort to realize the concept of Sentul City as a destination and a knowledge city, PT Sentul City Tbk. developed a recreational facility by building ecopark. Sustainable management of the landscape ecopark may have implications for the Sentul City as an eco city. The purpose of this study is to analyze the implementation of the existing landscape, evaluation of landscape development, and make landscape management plan. With the research object Eco-Art Park Sentul City, this study used methods of surveys, questionnaires, interviews, and Analytical Hierarchy Process (AHP). Analysis of the implementation of the existing landscape Eco-Art Park Sentul City shows that the landscape has not fulfilled the criteria of ecological park. Basic concepts and landscape development has not led to the ecological park. Development landscape changes related to adjustments and the desire of the directors. In the management and maintenance of landscapes, operationally not lead to ecological park. In the preparation of the management plan, there are recommendations to restructure the management and the addition of landscape maintenance schedule.
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Judul: Pengelolaan Lanskap berdasarkan Kualitas Jasa Lanskap di Kawasan Sentul City, Bogor
Abstrak: Sentul City sebagai kota satelit merupakan kota berkelanjutan terencana dengan memperhatikan kebutuhan pemukiman bagi manusia. Sentul City bertempat di wilayah Kabupaten Bogor. Kawasan ini menghadirkan konsep Eco City yang melibatkan aspek ekologi, ekonomi, sosial, dan budaya dengan alam serta mempertimbangkan dampak lingkungan dan meminimalisir penggunaan sumber daya luar. Konsep Eco City sebagai konsep pembangunan berkelanjutan memiliki beberapa indikator salah satunya peningkatan kualitas kehidupan masyarakat kota yang dinilai berdasarkan penilaian kualitas jasa lanskap Peningkatan jumlah penduduk memicu beralih fungsi penggunaan lahan khususnya lahan bervegetasi menjadi lahan terbangun. Hal ini mengakibatkan menurunnya kualitas jasa lanskap secara tidak langsung. Perubahan tutupan lahan berdampak pada perubahan kualitas jasa lanskap. Oleh karena itu untuk mengetahui seberapa besar terjadinya penurunan kualitas jasa lanskap perlu dilakukan pengkajian terhadap perubahan jasa lanskap di kawasan Sentul City Bogor pada tahun 2010 dan 2015. Hasilnya, lahan terbangun dan lahan kebun campuran meningkat sedangkan lahan pertanian dan lahan terbuka menurun. Fokus kajian jasa lanskap pada penelitian ini adalah penyimpanan cadangan karbon, keanekaragaman hayati, keindahan lanskap, pengaturan tata air, dan ameliorasi iklim. Nilai jasa lanskap pada tahun 2015 menurun di Sentul City, namun tetap dalam kondisi cukup baik. Hal ini terjadi karena lahan pertanian yang memiliki nilai dan kualitas jasa lanskap tertinggi nilainya turun sedangkan lahan terbangun yang memilki nilai dan kualitas jasa lanskap terendah nilainya naik. Kemudian hasil tersebut dianalisis dengan metode Strength, Weakness Opportunity, and Threats (SWOT) sehingga didapatkan enam rekomendasi pengelolaan kawasan Sentul City yang berkelanjutan.
Keyword: eco city, jasa lanskap, peningkatan kualitas hidup, perubahan lahan, pengelolaan lanskap

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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