Judul: Perbandingan Pemberian P-PRP dan L-PRP Alogenik dan  Xenogenik Terhadap Persembuhan Luka Sayat pada Tikus
Abstrak: Luka insisi adalah bentuk kerusakan jaringan kulit akibat teriris benda tajam. Salah satu pemanfaatan darah untuk pengobatan alternatif luka yaitu Platelet-Rich Plasma (PRP). Penelitian ini bertujuan membandingkan pemberian PRP dengan metode Pure Platelet-Rich Plasma (P-PRP) dan Leukocyte and Platelet-Rich Plasma (L-PRP) menggunakan darah alogenik dan xenogenik terhadap parameter persembuhan luka sayat pada tikus. Sebanyak 18 ekor tikus, masing-masing disayat lima luka pada punggungnya, diberi perlakuan pemberian sediaan L-PRP dan PPRP dari darah tikus (alogenik), L-PRP dan P-PRP dari darah kelinci (xenogenik) dan NaCL 0.9% (kontrol negatif). Pengambilan sampel dilakukan pada hari ke-3, 5 dan 7. Hasil penelitian menunjukkan luka yang diberikan P-PRP dan L-PRP baik alogenik dan xenogenik mempercepat persembuhan luka. Luka yang diberikan PPRP lebih cepat kering dan menutup dibandingkan kelompok lainnya dan juga menunjukkan terbentuknnya jaringan granulasi, epitelisasi, dan deposisi kolagen yang lebih cepat. Tidak ditemukan reaksi rejeksi tubuh terhadap pemberian PRP baik yang berasal dari darah alogenik dan xenogenik., Incisional wounds are a form of skin damage caused by sharp objects. One of the utilizations of blood for alternative wound treatment is Platelet-Rich Plasma (PRP). This study aims to compare the administration of PRP with the Pure Platelet-Rich Plasma (P-PRP) and Leukocyte and Platelet-Rich Plasma (L-PRP) methods using allogeneic and xenogeneic blood on the parameter of incision wound healing in rats. A total of 18 rats, each incised five wounds on their backs and treated with L-PRP and P-PRP from rat blood (allogenic), L-PRP and P-PRP from rabbit blood (xenogeneic) and NaCL 0,9% (negative control). Skin samples were taken on the 3rd, 5th, and 7th days. The results showed that wounds treated with P-PRP and L-PRP both allogeneic and xenogeneic promoted wound healing. Wounds treated with P-PRP dried and closed faster than other groups. Furthermore, P-PRP groups showed the faster formation of granulation tissue, epithelialization, and collagen deposition. There was no rejection reaction to the administration of PRP from both allogeneic and xenogeneic blood.
Keyword: allogeneic, incision wound, PRP, wound healing, xenogeneic

Judul: Test the Effectiveness of the Combination Gel of Turmeric Nanoparticles and Sea Cucumber: Histopathological Study of Skin Incision Wound Healing
Abstrak: Luka adalah terputusnya kontinuitas jaringan kulit. Luka akan menimbulkan rasa tidak nyaman pada penderitanya. Penelitian ini adalah bagian dari uji pendahuluan untuk mengevaluasi aplikasi kombinasi gel nanopartikel ekstrak kunyit dan jeli gamat untuk proses penyembuhan luka sayat pada tikus Sprague-Dawley berdasarkan pengamatan mikroskopis. Kulit 10 ekor tikus jantan disayat pada bagian punggung. Perlakuan dibagi menjadi lima kelompok yaitu, kontrol negatif (P0), gel kombinasi 0,5% (P1), 1%(P2), 2% (P3), dan kontrol positif (P4). Pengobatan dilakukan setiap hari selama seminggu. Secara histopatologi, spesimen diwarnai dengan Hematoksilin-Eosin untuk mengamati struktur kulit dan AE1/AE3 untuk melihat ekspresi sitokeratin. Pengamatan dievaluasi pada hari ke-2 dan ke-7 pasca perlukaan. Parameter histopatologi yang diamati adalah keropeng, epitelisasi, dan neovaskularisasi. Data disajikan secara deskriptif melalui foto. Hasil pengobatan luka gel kombinasi hari ke-2 dan ke-7 menunjukkan luka mengalami penyembuhan. Penyembuhan pada luka yang diobati dengan gel kombinasi konsentrasi 0,5% paling baik dibandingkan pengobatan konsentrasi lainnya., Wound is a break in the continuity of skin tissue. The wound will cause discomfort in the sufferer. This study is part of a preliminary test to evaluate the application of a combination of turmeric extract nanoparticle and jelly gamat for the wound healing process in Sprague-Dawley rats based on microscopic observations. The skins of 10 male rats were cut 3 cm left lateral area. The treatments were divided into five groups namely, negative control (P0), 0,5% gel combination (P1), 1% (P2), 2% (P3), and positive control (P4). Treatment was given everyday in a week. Histopathologically, the specimens were stained with Hematoxylin-Eosin to observe the skin structure and AE1 / AE3 to observe cytokeratin expression. The observations were evaluated on the second and seventh days post-injury. The histopathological parameters observed were scab, epithelial formation, and neovascularization. Data were presented descriptively through light microscope. The results of wound treatment on second and seventh day showed that the wound had a healing process. Healing of wounds treated with a 0.5% combination gel is the best among other consentration of treatment.
Keyword: jelly gamat, microscopic, turmeric, wound healing

Judul: Modeling Multi-Agent in Futsal Sport Using Finite State Machine.
Abstrak: Building agents for futsal scenario requires methodologies for implementing high-level complex behavior and efficient programming. With that hypothesis in mind, this paper will show that we can develop futsal agents using simple logic and rule-based manner with Finite State Machine (FSM). FSM provides a powerful way to describe dynamic behavior of systems and components. The systems adapt specific behaviors with the main focus on how agents should behave for current situation. This research is designed with State design pattern to implement FSM in object oriented languages. In order to describe procedural aspects of the agents behavior, the state machine represented by state diagram. Because of this, we can revise behavior of agents which is triggered by external events. From this research the system can describe agent’s behavior and specified the state of the current situation. Keywords: Multi-agent, Finite State Machine, object oriented, State design pattern.
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