Judul: Mapping of Coastline Changes in the Coastal of Bantul Regency Using Sentinel-2A Satellite Imagery
Abstrak: Pesisir merupakan wilayah yang kompleks akibat interaksi darat dan laut sehingga mudah mengalami perubahan secara fisik seperti perubahan garis pantai. Perubahan garis pantai penting diketahui untuk kajian pengelolaan kawasan pesisir, pemodelan pesisir, studi akresi-abrasi, serta analisis wilayah bahaya. Penelitian bertujuan memetakan dan menghitung laju perubahan garis pantai di Kabupaten Bantul, Daerah Istimewa Yogyakarta menggunakan citra Sentinel-2A pada tahun 2017, 2018 dan 2021. Metode digital shoreline analysis system (DSAS) digunakan untuk menghitung perubahan garis pantai secara statistik maupun geospasial. Lokasi penelitian terbagi menjadi 15 sub-zona dimana abrasi tertinggi terjadi pada Desa Parangtritis bagian timur (Sub-zona E3) dengan laju perubahan garis pantai mencapai -10,03 m/tahun. Abrasi dipengaruhi landainya kondisi pantai, gelombang dengan tinggi mencapai 2,39 m dan arus dengan kecepatan mencapai 0,24 m/s yang menggerus garis pantai serta tidak adanya penghalang di kawasan pantai. Akresi tertinggi terjadi di Desa Parangtritis bagian barat (Sub-zona E1) dengan laju perubahan garis pantai mencapai 9,20 m/tahun. Akresi dipengaruhi material sedimen dari darat yang mengendap dan menambah area garis pantai serta bergeraknya pasir oleh angin di sekitar gumuk pasir., Coastal is a complex area due to land and sea interactions so that it is easy to experience physical changes such as changes in coastlines. Coastline changes are important to know for coastal area management studies, coastal modeling, accretion-abrasion studies, and hazard area analysis. The study aimed to map and calculate the rate of change in coastlines in Bantul Regency, Yogyakarta Special Region using Sentinel-2A imagery on 2017, 2018 and 2021. The digital shoreline analysis system (DSAS) method used to calculate shoreline changes statistically and geospatially. The research location divided into 15 sub-zones where the highest abrasion occured in east Parangtritis Village (E3 sub-zone) with a coastline change rate of -10,03 m/year. Abrasion influenced by gentle coastal conditions, waves with a height of 2.39 m and currents with a speed of 0.24 m/s which erodes the coastline and there is no barrier in the coastal area. The highest accretion occurred in west Parangtritis Village (E1 sub-zone) with a coastline change 9,20 m/year. Accretion influenced by sedimentary material from land that settled and added to the coastline area and the movement of sand by the wind around the sand dune.
Keyword: abrasi, akresi, DSAS, Kabupaten Bantul, abrasion, accretion, Bantul Regency

Judul: Mapping of Coastline Changes Using Satellite Imagery on the Coast of Tegal Regency, Central Java
Abstrak: AMIN FAUZI. Pemetaan Perubahan Garis Pantai Menggunakan Citra Satelit di Pesisir Kabupaten Tegal, Jawa Tengah. Dibimbing oleh JAMES PARLINDUNGAN PANJAITAN dan BISMAN NABABAN. Daerah pesisir di Kabupaten Tegal mempunyai pemanfaatan ruang lahan yang cukup intensif yang perlu ditata dengan baik. Salah satu hal yang dapat menjadi acuan untuk penataan ruang lahan adalah perubahan garis pantai. Penelitian ini bertujuan untuk memetakan dan menganalisis perubahan garis pantai menggunakan citra satelit Sentinel 2A di pesisir Kabupaten Tegal tahun 2015 – 2019. Metode algoritma yang digunakan yaitu Normalized Difference Water Index (NDWI) dan metode analisis Digital Shoreline Analysis System (DSAS). Hasil penelitian menyebutkan nilai NDWI yang lebih besar dari nol diasumsikan sebagai badan air dan jika lebih kecil dari nol diasumsikan sebagai daratan. Abrasi terbesar terjadi di subzona A3 (Desa Maribaya) dengan nilai - 131,86 m dengan rata- rata kemunduran 33,44 m/tahun. Kemunduran garis pantai di Desa Maribaya tersebut terjadi akibat fenomena angin, gelombang besar, dan konversi lahan untuk dijadikan tambak ikan. Nilai perubahan akresi terbesar terjadi di subzona B2 yaitu dengan nilai sebesar 30,95 m. Hal ini terjadi di sisi area yang memiliki bangunan pelindung pantai berupa bangunan jetty. Perubahan garis pantai yang terjadi bersifat ringan hingga sangat berat sehingga diperlukan penanganan khusus agar pembangunan wilayah pesisir Kabupaten Tegal dapat meminimalisir kerugian dari perubahan tersebut. Kata kunci: Abrasi, Akresi, DSAS, Garis Pantai, NDWI, AMIN FAUZI. Mapping of Coastline Changes Using Satellite Imagery on the Coast of Tegal Regency, Central Java. Supervised by JAMES PARLINDUNGAN PANJAITAN and BISMAN NABABAN. The coastal area in Tegal Regency has a fairly intensive land use so that it needs to be managed properly. One of the parameter that used for the coastal management is the change of the coastline. This study aims to map and analyze shoreline changes using Sentinel 2A satellite imagery on the coast of Tegal Regency in 2015 – 2019. The algorithm method used is the Normalized Difference Water Index (NDWI) and the Digital Shoreline Analysis System (DSAS) analysis method. The results of the study stated that the NDWI value greater than zero was assumed to be a body of water and if it was less than zero it was assumed to be land. The biggest abrasion occurred in subzone A3 (Maribaya Village) with a value of -131.86 m with an average decline of 33.44 m/year. The retreat of the coastline in Maribaya Village was due to the phenomenon of wind,large waves, and land conversion to to the fish pond area. The value of the largest accretion change occurred in subzone B2 with a value of 30.95 m. This happens on the side of the area that has a coastal protection building in the form of a jetty building. The changes in the coastline that occur are mild to very severe so special handling is needed so that the development of the coastal area of Tegal Regency can minimize losses from these changes. Keywords: Abrasion, Accretion, Coastline, DSAS, NDWI
Keyword: Abrasion, Accretion, Coastline, DSAS, NDWI

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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