Judul: Aktivitas antikanker ekstrak etanol daun surian (Toona sinensis) pada tikus betina galur sprague-dawley yang diinduksi 7,12-Dimetilbenz(α)Antrasena
Abstrak: Surian leaves (Toona sinensis) contain bioactive compounds, which have been reported as an anticancer agent. However, in vivo study of surian leaves as anticancer has not been carried out. This research was conducted to investigate anticancer activity of surian leaves ethanol extract in rats that had been induced with 7,12-dimetilbenz(α)antrasena (DMBA). Twenty female rats were divided into 5 groups (n=4), namely normal, cancer, doxorubicin, extract I and II groups. Cancer induction was carried out once by injecting DMBA via intravena with a dose of 25 mg/Kg BW. The extract I and II groups were administered orally by surian leaves ethanol extract at 500 mg/Kg BW and 750 mg/Kg BW for 30 days, meanwhile doxorubicin group was administered by doxorubicin once a week for 3 weeks at 2 μg/200 g BW via intravena. Anticancer activity was determined by observing the decrease of tumor volume that was calculated based on number of nodules and cancer diameter. Cancer volume of doxorubicin group decreased by 6.438 cm3. In the mean time, cancer, extract I, and extract II groups consecutively increased by 25.832 cm3, 25.836 cm3 and 23.279 cm3 respectively. This results showed that the extract was not effective in repressing cancer growth.
Keyword: 

Judul: Aktivitas Ekstrak Etanol Daun Surian (Toona Sinensis Roem.) Sebagai Agen Antidiabetogenik Pada Tikus Yang Diinduksi Streptozotosin
Abstrak: Ekstrak daun surian (Toona sinensis Roem.) di Indonesia dilaporkan memiliki senyawa aktif yang berpotensi sebagai antihiperglikemia dan telah diuji secara in vitro. Penelitian ini bertujuan mengukur kadar glukosa darah dan insulin serum serta menganalisis kondisi histopatologi pankreas melalui pewarnaan Haematoxylin-Eosin (HE) pada tikus jantan galur Sprague-Dawley yang diinduksi streptozotosin setelah pemberian ekstrak etanol daun surian. Selain itu, dilakukan juga pengukuran bobot badan dan konsumsi pakan selama perlakuan. Rata-rata rendemen ekstrak etanol yang diperoleh sebesar 25.57% dan analisis fitokimia ekstrak ini memberikan hasil positif pada senyawa flavonoid, fenolik hidrokuinon, tanin, saponin, steroid dan glikosida. Peningkatan kadar glukosa darah sebesar 21.22% hingga akhir masa perlakuan terjadi pada kelompok ekstrak 200 mg/kg BB, ekstrak 400 mg/kg BB mampu menurunkan kadar glukosa darah tikus diabetes sebesar 26.62% pada minggu pertama, namun peningkatan kadar glukosa darah yang signifikan sebesar 24.80% terjadi setelah induksi STZ hingga akhir perlakuan. Oleh sebab itu, ekstrak etanol daun surian dosis 200 mg/kg BB dapat dikatakan tidak memiliki aktivitas antidiabetogenik, sedangkan dosis 400 mg/kg BB tidak efektif sebagai agen antidiabetogenik.
Keyword: antidiabetogenik, streptozotosin, T.sinensis

Judul: Hamiltonian formulation for linear waves motion in two layers fluid
Abstrak: The surface wave could be considered as a wave that separates two fluids, namely water and air. Based on this assumption, it is introduced the interfacial wave, a wave between two layers of fluid with different density. The formulation of interfacial waves motion begins with deriving the base equation of irrotational ideal fluid. Furthermore, according to irrotational fluid assumption, the base equation can be stated in velocity potential. In this derivation, the fluids domain is assumed to be restricted by rigid lid boundary conditions, both at the upper and lower limit. Therefore, the interfacial waves motion can be explained in a hamiltonian formulation. In the hamiltonian formulation, total energy is defined as the sum of kinetic and potential energy. The hamiltonian system is obtained from reduction of kinetic energy by using the Dirichlet Neumann Operator. The resulted kinetic energy equation is nonlinear. Therefore, this form is linearized by first part of the Taylor expansion. This linearization gives a dispersion relation of linear wave. Based on this dispersion relation, the phase speed of the linear wave depends on the density ratio of the two layers fluid.
Keyword: