Judul: Structural Equation Model Data In Case Malnutrition On Brain Development
Abstrak: Saat ini Indonesia mengalami masalah gizi yang cukup kompleks. Berdasarkan Global Nutrition Report tahun 2014, Indonesia termasuk di dalam 17 negara diantara 117 negara yang mempunyai ketiga malnutrisi, yaitu kerdil, kekurangan berat badan, dan kelebihan berat badan. Dewasa ini Indonesia menghadapi beban ganda malnutrisi, yakni masalah kekurangan gizi dan masalah kelebihan gizi. Masalah kekurangan gizi dan kelebihan gizi sangat berpengaruh terhadap masa kembang pertumbuhan anak pada usia lima tahun ke atas., Currently Indonesia is experiencing nutritional problems which are quite complex. Based on the Global Nutrition Report 2014, Indonesia is at rank 17th among 117 countries that have three types of malnutrition, ie stunting, wasting and overweight. Today Indonesia is facing a double burden of malnutrition; undernutrition and overnutrition problems, which are greatly affect the future growth and development of children at the age of five upwards.
Keyword: Latent Variables, Malnutrition, Structural Equation modeling, Latent analysis

Judul: Praktek Kesehatan, Morbiditas, Stimulasi Psikososial, dan Perkembangan Balita Stunting dan Normal
Abstrak: Stunting it’s a nutrition problem in Indonesia, prevalence of stunting in Indonesia is 35.6%. The impact of chronic under nutrition in children can decreased brain development that can result in low intelligence, learning ability in children. The purpose of this study was to identify feeding practices, food consumption and psychosocial stimulation and it’s relation to child development in stunting and normal under five children. Design used in this study was a crosssectional study. Subjects in this study were 92 children under the age of 36-60 months in the village Cibatok Dua. The result showed, there was significant differences in food consumption and language development between stunting and normal under five children (p<0.05). Correlation test result is significant positive relation between food consumption and nutritional status (HAZ), nutritional status (HAZ) and cognitive development, and nutritional status (HAZ) and language development (p<0.05).
Keyword: child development, stunting, food consumption, feeding practice

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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