Judul: Aktivitas Aminotransferase dan Peroksidasi Lipid pada Tikus Hiperkolesterolemia yang Diberi Ekstrak Jamur Tiram Putih
Abstrak: White oyster mushroom extract contain lovastatin which can be used as anticholesterol agent. But, this extract is thought to be hepatotoxic in certain doses. The aim of this research was to analyze AST and ALT activities and to measure concentration of lipid peroxide in liver of hypercholestrolemic mice induced with white oyster mushroom extract. Animals used in this research were 35 males Sprague Dawley mice that have been divided into five groups, that are normal (N) group, hypercholesterolemia (HK), lovastatin (L), white oyster mushroom extract dose 30 mg/kg BB (E1) and white oyster mushroom extract dose 60 mg/kg BB (E2). Administration of white oyster mushroom extract dose 30 mg/kg BB decreased 32.92% AST activity, 34.73% ALT activity and also lowered 54.05% lipid peroxide concentration than HK group. Induction with white oyster mushroom extract dose 60 mg/kg BB decreased 38.78% AST activity, 24.62% ALT activity and also lowered 17.50% lipid peroxide concentration than HK group. This data showed that the oyster mushroom extract was not affect the function of rat liver and could act as antioxidant.
Keyword: white oyster mushroom, lipid peroxide, enzyme, AST, ALT

Judul: Aktivitas Antioksidan Superoksida Dismutase Pada Hati Tikus Hiperkolesterolemia Yang Diberi Ekstrak Kulit Mahoni (Swietenia macrophylla)
Abstrak: Mahoni’s stem bark is wood industrial waste that rich in secondary metabolites. Research about its antioxidant potency has been done previously. This research was performed to study about the mahoni’s bark extract mechanism on lowering lipid peroxidation by determining the activity of endogenous antioxidant in the liver. Thirty five male rats were divided into 5 groups (n=7) normal, hypercholesterolemic, lovastatin, extract 1, and extract 2 group. Normal group fed with standard rat chow, hypercholesterolemic group (HK) with cholesterol chow (1,5%) and PTU (0,5 mg/KgBW), lovastatin group (HK + lovastatin 0,2857 mg/KgBW), E1 group (HK+ mahoni extract 4,2 mg/KgBW), and E2 group (HK + mahoni extract 21 mg/KgBW). Experiments were carried out for 8 consecutive weeks. The rat liver superoxide dismutase (SOD) antioxidant activity were determined by calculating the inhibition percentage of pyrogallol autooxidation process became purpurogallin by SOD, total formed purpurogallin was measured using spectrophotometer with 340 nm wavelength. The SOD antioxidant activities in normal group of rats was 47.96±12.37%. There was not any significant SOD antioxidant activities difference between all rats group of treatment (=0.05). These result showed that mahoni’s bark extract roles as antioxidant in rats was achieve not by increasing the activity of superoxide dismutase but by other mechanism.
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Judul: Mempelajari Model Rancangan Hidrolika Sub Unit Irigasi Curah dengan Tekanan Rendah
Abstrak: Faktor penting dalam keberhasilan penerapan sistem irigasi curah adalah perancangan yang tepat dan efisiensi operasional dari sistem yang dirancang. Desain irigasi curah dilakukan dengan beberapa tahapan. Perhitungan rancangan hidrolika sub unit merupakan tahapan kunci dalam proses desain irigasi curah. Persyaratan hidrolika jaringan perpipaan harus dipenuhi untuk mendapatkan penyiraman yang seragam. Jumlah dan spesifikasi sprinkler (pencurah) maupun jenis dan diameter pipa yang beredar di pasaran sangat beragam. Tahapan rancangan hidrolika sub unit biasa dilakukan dengan metoda coba-ralat (trial-error method). Hal ini cukup rumit dan membutuhkan waktu yang tidak sedikit. Maka dibutuhkan suatu metoda perhitungan rancangan hidrolika sub unit yang sederhana sehingga memudahkan dan meminimalkan kesalahan dalam perancangan irigasi curah.
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