Judul: Kajian Konsep Desain Lanskap Jalan Kolonial Kota Bogor.
Abstrak: Bogor City is one of the historic sites in the European colonial era in Indonesia. One of a heritage form in that era is the landscape of colonial. The form of colonial landscape also reflected in the design of street landscape in Bogor City. Study on Design Concept of Colonial Streetscape at Bogor City aims to identify the component of street landscape whose colonial character, exploring the design concept of colonial street landscape, and composing the design concept of street landscape that having colonial character in Bogor. This research has obtained through descriptive analysis by field observation and tracing the information of history. Generally, three main components of colonial street landscape design those are the main elements of street, complementary elements, and colonial building. Complementary elements that characterizing the colonial has the feel of a classic Victorian, gothic and use of industrial materials. The third component of colonial street lanscape is a building that reflects the Dutch colonial era and The important part of it is the facade of the building.
Keyword: colonial concept, street landscape design

Judul: Kajian Lanskap Pertigaan Jalan Lingkar Kebun Raya Bogor
Abstrak: Kawasan Jalan Lingkar Kebun Raya Kota Bogor terletak di tengah-tengah kota dan termasuk dalam kawasan landmark Kota Bogor dengan adanya Kebun Raya Bogor. Banyaknya pengguna jalan di sekitar kawasan ini menyebabkan berbagai permasalahan, di antaranya kemacetan lalu lintas, polusi udara, menurunnya tingkat kenyamanan pengguna jalan, dan masalah infrastruktur jalan yang tidak hanya menjadi jalur lalu lintas kendaraan saja, tetapi peran sosial dan potensi koridor jalan pada kawasan tersebut. Masalah kemacetan kendaraan yang menonjol terlihat pada setiap titik-titik pertigaan jalan (traffic island) di kawasan Jalan Lingkar Kebun Raya Bogor. Berdasarkan permasalahan tersebut, diperlukan sebuah konsep desain lanskap jalan yang mampu mempengaruhi kualitas lanskap jalan yang ada dengan menciptakan suasana yang nyaman dan estetis sesuai dengan keadaan Kota Bogor, khususnya pada Jalan Lingkar Kebun Raya Bogor sehingga mampu memberikan pengalaman visual yang menyenangkan ketika melewati jalan ini. Penelitian ini dilaksanakan di Jalan Lingkar Kebun Raya Bogor, Kota Bogor terhitung mulai bulan April 2009 sampai dengan bulan September 2009. Metode yang digunakan adalah metode deskriptif dengan teknik survei, wawancara secara langsung dengan kuisioner, serta simulasi 3D menggunakan program Google SketchUp dengan bantuan peta dasar dari Dinas Cipta Karya dan Tata Ruang Kota Bogor. Pada pelaksanaannya, penelitian ini dilakukan secara bertahap, yakni tahap prasurvei, tahap survei, tahap analisis dan sintesis, dan tahap pengembangan konsep.
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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