Judul: Aktivitas anti Mutagenesis isoflavon glikosida hasil reaksi Transglikosilasi oleh Siklodekstrin slukanotransferase (ee 2.4.1.19) dari Bacillus maceralls
Abstrak: Produk pangan dengan bahan dasar kedelai seperti tempe, tahu dan susu sangat populer di masyarakat. Harganya yang murah, nutrisi esensial yang tinggi dan kandungan senyawa aktif (isoflavon) yang dimiliki, menyebabkan kedelai banyak menarik perhatian untuk diteliti. Telah diketahui beberapa senyawaan polifenol tenuasuk isoflavon memiliki aktivitas antibakteri, anti melanogenesis, antimutagen, dan antikauker.
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Judul: Analisis aktivitas siklodekstrin glukanotransferasi dan sintesis polifenol-@ glikosida secara enzimatik
Abstrak: Senyawa polifenol-a-glikosida telah dimanfaatkan sebagai agen yang efektif pada proses-proses biologi. Sintesis senyawa polifenol-a-glikosida dengan menggunakan enzim siklodekstrin glukano- transferase (CGTase) belum diteliti secara eksploratif. Polifenol-a-glikosida dapat disintesis oleh CGTase dengan menggunakan akseptor senyawa polifenol. Dalam penelitian ini dilakukan analisis terhadap aktivitas CGTase lima biakan yang disolasi dari kacang kedelai steril yang difermentasi secara alami dengan jerami padi yang masih segar, yaitu JI₂, JII, JIMI₂, JIII, dan JIII,, dan sintesis polifenol-a-glikosida. Pengujian aktivitas CGTase menggunakan metode Masataka et al. (1993), sintesis dan pemisahan produk transfer dengan menggunakan metode Sulistyo et al. (1994). Pengujian gula total pada tiap fraksi hasil elusi dengan kolom arang aktif dianalisis dengan menggunakan metode Dubois (1956). Kelima biakan yang diisolasi dari jerami yang mengandung kacang kedelai menunjukkan aktivitas CGTase, tetapi hanya isolat JI₂, JII, dan III, yang menunjukkan aktivitas transfer pada akseptor hidrokinon, resolsinol dan piroketekol. Hasil identifikasi sampai tingkat spesies menunjukkan bahwa isolat JI, adalah Bacillus subtilis dan isolat JII, adalah Bacillus megaterium, sedangkan isolat JII, hanya teridentifikasi sampai tingkat genus yaitu Bacillus. Hasil pemisahan dengan kolom arang aktif, menunjukkan bahwa produk transfer terelusi ke luar pada etanol 10%. Produk transfer yang dibentuk dari 2.5 gr pati dan 1gr hidrokinon sebesar 0.74 mg (0.03%). Produk transfer yang diinginkan belum murni, karena masih tercampur beberapa senyawa turunan anilin lainnya dengan berat molekul yang lebih kecil. Oleh karena itu fraksi yang mengandung produk transfer masih perlu dimurnikan lebih lanjut.
Keyword: Siklodekstrin

Judul: Thermal Characteristics and Dynamics of Tropical Cyclone over Western North Pacific Ocean: A Case Study of Typhoon Songda (Chedeng) 2011
Abstrak: The frequent occasion of Tropical Cyclone (TC) over Western North Pacific (WNP) Ocean lies from 10˚N to 26˚N and 121˚E to 170˚E. Sources of TC development come from warm ocean temperature where latent heat is released during condensation processes and subsequently concentrated in the boundary layer. Relative humidity at 850-700 hPa is responsible to produce the most intense storm. Meanwhile, weak vertical wind shear between 850-200 hPa is one of the dynamical factors that lead to the development of TC. Pressure level of 850-200 hPa is chosen to minimize the thermodynamic effect in the lower troposphere. Typhoon Songda (Chedeng in the Philippines) or TSC lasted from May 18th to 30th, 2011 and strengthened into powerful Super Typhoon stage between May 24th and 27th. Long curving track and the exhibition of all sequences of TC life cycle, TSC is then considered as an ideal case of TC. The objective of the study with case of TSC is to investigate the role of thermal characteristics and dynamics on TC intensity. The research is carried out by using Advanced Research of Weather Research and Forecasting model (WRF ARW model) version 3.3. Two domains are employed in the model. The first domain situate from 02˚N to 40˚N and 118˚E to 149˚E and cover spatial resolution () of 33.1 km. The second domain situate from 09˚N to 27˚N and 119˚E to 132˚E with of 11 km. Timestep of the model () is 120 seconds. The model is supported by the following physical parameterization, i.e., Yonsei University Scheme (YSU) in the boundary layer, Kain-Fritsch scheme (KF) in the cumulus, and WRF Single-Moment 3-class scheme in the microphysics. Initial meteorological condition prior to the formation of the cyclone is generated using WRF ARW standard-release model. Sensitivity of the model output is obtained from a selected single-parameter change scenarios, namely, 10 % to 20 % decrease and increase of wind shear initial data at 850-200 hPa, and by 10 % to 20 % decrease of relative humidity initial data at 850-700 hPa. The result showed that the negative correlations between wind shear and intensity are found in wind shear scenarios. Wind shears of 10 ms-1 which lead to strengthening of the wind intensity in the early period of Typhoon development are found in wind shear scenarios. The effect of wind shear changes on wind intensity is statistically significant in the 20 % wind shear scenarios. During mature stage, weak wind intensity occurred when wind shear increase as given in the WRF standard-release and the 20 % decreasing scenario. Different situation is found in the 20 % increasing scenario where wind shear tend to weak and lead to strong wind intensity at this stage. Meanwhile, the reduction of moisture supply at 850-700 hPa resulting from 20 % decreasing relative humidity play a major role in the weakening of wind intensity and reduces mechanical energy of the cycle process as much as 300 J kg-1.
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