Judul: Social Media and Early Marriage Among Rural Adolescents (Case: Desa Pamijahan, Kecamatan Pamijahan, Kabupaten Bogor)
Abstrak: Pandangan bahwa pernikahan dini sebagai sesuatu hal yang wajar dan tidak perlu dipermasalahkan memberikan dampak terhadap meningkatnya pernikahan usia dini di pedesaan. Salah satu faktor lainnya yaitu seiring dengan perkembangan internet, remaja di pedesaan sudah terbiasa untuk menjalin pertemanan dan mencari informasi melalui media sosial. Penelitian ini bertujuan untuk menganalisis hubungan penggunaan media sosial dengan sikap remaja tentang pernikahan dini di Desa Pamijahan. Jumlah responden yang telah diteliti sebanyak 60 orang remaja dengan menggunakan pendekatan kuantitatif melalui metode survei yang memanfaatkan kuesioner dan didukung oleh data kualitatif dari hasil wawancara mendalam serta observasi. Hasil penelitian ini menunjukkan bahwa tidak terdapat hubungan nyata antara tingkat penggunaan media sosial dengan sikap remaja tentang pernikahan dini, tetapi setelah tingkat penggunaan media sosial diuraikan per aplikasi, ditemukan beberapa aplikasi media sosial yang berhubungan secara signifikan dengan sikap remaja tentang pernikahan dini. Kecenderungan remaja Desa Pamijahan untuk menikah dini disimpulkan termasuk dalam kategori sedang karena masih ada remaja yang ingin dan mau melakukan pernikahan dini, tetapi tingkat penggunaan media sosial masih belum menjadi salah satu faktor remaja melakukan pernikahan dini., The view that early marriage is something that is normal and does not need to be questioned has an impact on the increase in early marriage in rural areas. One other factor is that along with the development of the internet, youth in rural areas are used to making friends and seeking information through social media. This study aims to analyze the relationship between social media use and adolescent attitudes about early marriage in Pamijahan Village. The number of respondents who were studied was 60 teenagers using a quantitative approach through a survey method using a questionnaire and supported by qualitative data from the results of in-depth interviews and observations. The results of this study indicate that there is no significant relationship between the level of social media use and adolescent attitudes about early marriage, but after the level of social media use is described per application, several social media applications are found to be significantly related to adolescent attitudes about early marriage. It is concluded that the tendency of adolescents in Pamijahan Village to marry early is included in the moderate category because there are still teenagers who want and want to do early marriage, but the level of social media use is still not a factor for young people to marry early.
Keyword: early marriage, social media usage, teenager characteristics

Judul: Pengaruh status ekonomi keluarga terhadap motif menikah dini di Perdesaan
Abstrak: Pernikahan yang dilakukan pada perempuan di bawah umur berkaitan dengan kesiapan fisik maupun psikis yang belum mencapai kematangan termasuk pembentukan identitas diri maupun sosial individu sebagai remaja yang berada pada masa pencarian identitas. Tujuan penelitian ini adalah untuk mengidentifikasi motif-motif dan faktor yang melatarbelakangi pernikahan dini yang terjadi, serta menganalisis hubungannya terhadap pembentukan identitas. Penelitian ini dilakukan dengan menggunakan metode penelitian survei. Pengumpulan data dilakukan menggunakan teknik purposive sampling dengan jumlah responden sebanyak 30 orang. Pengujian pengaruh antara variabel faktor-faktor menikah dini terhadap motif menikah dini dilakukan dengan menggunakan uji regresi berganda, sedangkan variabel pembentukan identitas diuji melalui pendekatan kualitatif deskriptif. Hasil yang diperoleh menunjukkan bahwa pernikahan dini yang terjadi dilatarbelakangi oleh motif remaja untuk memenuhi kebutuhan akan keamanan, sosial, dan harga diri. Pembentukan identitas yang terbentuk pada remaja putri yang melakukan menikah dini ialah pembentukan identitas diri kuat dan pembentukan identitas sosial lemah., A marriage of under age women related with physical as well as psychological state of readiness which have not reached maturity include the formation of self identity and social identity as an adolescence that in fact are on the search for identity. The purpose of this research is to identify the motives and factors which aspects influenced early marriages that occurred, as well as analyzing its relationship towards the formation of identity. The research was carried out using survey research methods. Data collection was done using a purposive sampling technique with 30 respondents. Influence testing between variables factors of early married toward motives of early married conducted using test of multiple regression while formation of identity tested through by qualitatif description. The result showed that early marriage occurred by adolescence motives to fulfill the security, social, and self esteem. The identity formation related in adolescence who married early is strong formation self identity and weak formation social identity.
Keyword: Pernikahan dini, Faktor-faktor menikah dini, Motif menikah dini, Pembentukan identitas

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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