Judul: Desain Lanskap Kebun Percobaan Sindang Barang sebagai Sarana Agrowidyawisata
Abstrak: Sindang Barang Experimental Field (KPSB) is one of a supporting facilities for research, education, and community service. KPSB is one of University Farm (UF) of IPB, with total area 78 750 m2, consist of planting Bloks, research garden, building, and supporting facilities. Recently, KPSB is not used optimally and and not put in good use due to lack of facilities. Therefore, landscape design of KPSB is needed as a reference for future development of KPSB. The purpose of this study is designing an experimental field with techno-ecologycal farming concept. This research used survey and descriptive method with the design phase approach followed Bell (2008). The main design concept is techno-ecological agro tourism. This design was not only concern about research and education activities, but also how to support agro tourism. The zoning in this design are: welcome area (9%), agriculture (27%), education (23%), fisheries (11%), talun (20%), and tourism (10%). In the future, it is expected that agrotourism activities can be done well on KPSB.
Keyword: landscape design., landscape design., field laboratory, Agro-tourism

Judul: Perancangan Lanskap Peternakan Sebagai Sarana Agroedutourism di Kampus Dramaga Institut Pertanian Bogor
Abstrak: The environmental conditions is a factors affecting of livestock directly or indirectly. The field laboratory of small ruminants is a kind of the IPB facilities. The condition of field laboratory has a less support of environment for these activities. Livestock productivity and optimal quality can indirectly support the livestock farming activities (educational and breeding). In addition, to support and develop the field laboratory of small ruminant as agroedutourism tourist activities. The objectives of this study are to identify the potency and problem of the site as an object to support agroedutourism and also designing ruminant’s landscape in developing and supporting the agroedutourism in IPB. This research uses descriptive method, survey method to data collection, and refers to the stages of the work made by Booth (1983). The results of this research is the design landscape of the animal husbandry environment to supports educational activities and agroedutourism with consider amenities of user and animals that are there. The Field Laboratory Small Ruminant is determined by six zone. They are, welcome area 912.2 m² (4.5%), service 1 035.6 m² (5.2%), buffer 8 899.5 m² (44.3%), tourism, educational, and livestock farming area is 9 245.6 m² (46%). Landscape design of small ruminants laboratory can function properly in the future for agroedutourism activity
Keyword: agroedutourism, field laboratory, livestock farming

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
Keyword: