Judul: Strategi pengembangan ekowisata berbasis masyarakat di zona wisata Bogor Kabupaten Bogor:
Abstrak: Kabupaten Bogor mempunyai potensi ekowisata berupa potensi sumberdaya alam seperti pemandangan alam yang indah dengan latar Gunung Salak serta potensi budaya seperti kehidupan masyarakat, kesenian, upacara adat serta budaya bertani yang masih tradisional yang sangat potensial dalam pengembangan berbasis masyarakat. Dalam pengembangan wisata, pemerintah Kabupaten Bogor membuat zonasi dalam pengelolaannya. Salah satu bagian dari Kabupaten Bogor yang belum optimal dalam pengembangan ekowisata berbasis masyarakatnya yaitu di Zona Wisata Bogor Barat. Ekowisata Berbasis Masyarakat atau Community Based Ecotourism (CBE) merupakan konsep pengembangan ekowisata dengan melibatkan dan menempatkan masyarakat lokal yang mempunyai kendali penuh dalam manajemen dan pengembangannya sehingga memberikan kontribusi terhadap masyarakat berupa peningkatan kesejahteraan masyarakat lokal dan keberlanjutan kebudayaan lokal. Tujuan penelitian ini yaitu memetakan daerah potensial pengembangan CBE dan menyusun strategi pengembangan ekowisata berbasis masyarakat di Zona Wisata Bogor Barat. Selain itu untuk menspasialkan informasi non-spasial dengan mengidentifikasi objek dan daya tarik wisata berupa kondisi biofisik, sosial-budaya, ekonomi, dan permasalahan dalam pengembangan ekowisata berbasis masyarakat, menganalisis kesiapan masyarakat serta menganalisis secara spasial maupun deskriptif desa yang potensial untuk pengembangan ekowisata berbasis masyarakat.
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Judul: Development Strategy of Situ Gede Ecotourism, West Bogor District, Bogor City
Abstrak: Situ Gede merupakan kawasan ekowisata yang memanfaatkan situ sebagai objek wisata. Pengembangan ekowisata harus memperhatikan aspek-aspek ekologis, ekonomis dan sosial. Penelitian ini bertujuan merumuskan faktor-faktor yang memengaruhi kunjungan situ serta memberikan alternatif pengelolaan wisata di Situ Gede, Kecamatan Bogor Barat, Kota Bogor. Metode yang dilakukan dalam penelitian ini adalah fungsi permintaan, daya dukung kawasan, dan SWOT. Faktor yang memengaruhi kegiatan ekowisata secara signifikan adalah biaya perjalanan dan jarak. Total daya dukung kawasan Situ Gede sebesar 476 orang/hari dengan kunjungan wisata yang masih kurang atau undervisit. Alternatif pengelolaan untuk pengembangan ekowisata Situ Gede adalah memperluas akses jalan dan lahan parkir, melengkapi sarana dan prasarana yang mendukung dan kurang lengkap, serta melakukan kemitraan., Situ Gede is an ecotourism area that uses situ as a tourist attraction. Ecotourism development must pay attention to ecological, economic, and social aspects. This study aims to formulate the factors that influence visits to situ and provide alternative tourism management in Situ Gede, West Bogor District, Bogor City. The methods used in this research were demand function, carrying capacity, and SWOT analysis. Factors that affect ecotourism activities significantly are travel costs and distance. The total carrying capacity of Situ Gede area is 476 people/day with tourist visits that are still lacking or undervisit. The alternative managements used for the development of ecotourism are expanding access roads and parking lots, completing supporting and incomplete facilities and infrastructure, and establishing partnerships.
Keyword: carrying capacity, ecotourism, Situ Gede, SWOT

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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