Judul: Fraksi Distilat pada Distilasi Rebus Minyak Atsiri Rimpang Temu Hitam (Curcuma aeruginosa) dan Aktivitas Antibakterinya
Abstrak: Minyak atsiri rimpang temu hitam memiliki potensi sebagai antibakteri. Penelitian ini bertujuan menentukan waktu distilasi rebus yang optimum untuk menghasilkan minyak atsiri rimpang temu hitam dengan aktivitas antibakteri terbaik. Senyawa yang terdapat di dalam minyak atsiri rimpang temu hitam diidentifikasi menggunakan gas chromatography-mass spectrometry (GC-MS). Kandungan senyawa dominan tertinggi dari semua waktu distilasi pada minyak atsiri rimpang temu hitam adalah epikurzerenon (45%), eukaliptol (70,14%), dan kamfor (15,27%). Aktivitas antibakteri minyak astiri rimpang temu hitam ditentukan dengan metode difusi cakram terhadap bakteri Streptococcus mutans, Escherichia coli, dan Staphylococcus aureus. Potensi antibakteri terbaik didapatkan pada lama waktu distilasi 30 menit pertama untuk bakteri S. mutans, 30 menit kedua untuk bakteri E. coli, dan 30 menit kelima untuk bakteri S. aureus., Temu hitam’s rhizome essential oil has potential as an antibacterial. This study aims to determine the optimum length of boiled distillation time to produce temu hitam’s rhizome essential oil with the best antibacterial activity. Compounds contained in the essential oil of temu hitam’s rhizome were identified using gas chromatography-mass spectrometry (GC-MS). The highest content of the dominant compounds from all times of distillation in temu hitam’s rhizome essential oil was epicurzerenone (45%), eucalyptol (70.14%), and camphor (15.27%). Antibacterial activity of temu hitam’s rhizome essential oil was determined by disc diffusion method against Streptococcus mutans, Escherichia coli, and Staphylococcus aureus. The best antibacterial potential was obtained in the first 30 minutes of distillation for S. mutans bacteria, the second 30 minutes for E. coli bacteria, and the fifth 30 minutes for S. aureus bacteria.
Keyword: Antibakteri, Distilasi Rebus, GC-MS, Minyak Atsiri

Judul: Essential oil of temu hitam (Curcuma aeruginosa Roxb.)„s rhizomes, stems, and leaves as antibacterial toward Streptococcus mutans and biofilm degradator on teeth
Abstrak: Rimpang temu hitam banyak digunakan sebagai antibakteri. Penelitian ini membandingkan kemampuan minyak atsiri rimpang, batang, dan daun temu hitam sebagai antibakteri Streptococcus mutans dan pendegradasi biofilm pada gigi menggunakan metode mikrodilusi. Minyak atsiri diisolasi dengan distilasi uap. Potensi antibakteri terbaik adalah minyak rimpang KHM=konsentrasi hambat minimum=15.63 μg/mL dan KBM=konsentrasi bunuh minimum=1000 μg/mL. KHM rimpang sama dengan tetrasiklin. Setelah difraksionasi dengan kolom maupun kromatografi lapis tipis preparatif, KHM dan KBMnya tidak lebih baik. Senyawa 2,2,5-trimetil-2‟(H)-5‟-6‟-dihidropirano[3‟,4‟,g]indan-1-on diduga paling berperan sebagai antibakteri S. mutans. Kemampuan degradasi biofilm minyak atsiri kasar temu hitam kurang kuat. Minyak atsiri batang lebih baik mendegradasi biofilm (IC50=1347 μg/mL) daripada rimpang dan daun. Setelah difraksionasi, beberapa fraksi minyak atsiri rimpang (F1, F2, dan F3) lebih baik kemampuan degradasinya tetapi IC50 lebih tinggi dari klorheksidin., Rhizomes of temu hitam are widely used as antibacterial. This research compare the potency of essential oil of rhizomes, stems, and leaves of temu hitam as antibacterial toward Streptococcus mutans and biofilm degradator on teeth. The essential oil was isolated by steam distillation. Rhizome‟s essential oil showed good potency as antibacterial with MIC=minimum inhibition concentration=15.63 μg/ml and MBC=minimum bactericidal concentration=1000 μg/ml. MIC of rhizome was same with tetracycline. MIC and MBC of rhizome‟s essential oil was smaller than fraction of column and preparative thin layer chromatography. The 2,2,5-trimethyl-2‟(H)-5‟-6‟-dihydropyrano[3‟,4‟,g]indan-1-one give better potency as antibacterial toward S. mutans. Essential oil of temu hitam was not stronger as biofilm degradator. Stem‟s essential oil was the better essential oil (IC50=1347 μg/mL) to degradate biofilm than rhizome and leave‟s essential oil, but some of fraction of rhizome‟s essential oil (F1, F2, and F3) have better potency than stem‟s essential oil but the IC50 was higher than chlorhexidine. Keywords: Antibacterial, biofilm degradator, essential oil, Streptococcus mutans
Keyword: antibakteri, minyak atsiri, pendegradasi biofilm, Streptococcus mutans

Judul: Dynamics Model for Rural and Urban Economic Growth
Abstrak: Lewis theory of structural change has focused on mechanisms that allow countries to transform their domestic economic structure to a more modern economy. The proposed model deals with the mechanism of interaction between rural and urban Economic. This model is concerned with the process of labor transfer from rural to urban areas. This study aims to model the dynamics of economic growth in rural and urban areas, including determining the equilibrium solution and to carry out simulation of the model. The simulation results show that the transfer of labor from rural to urban areas will increase the rate of change of capital so that structural changes can be realized. In addition, increased propensity to save in rural areas will also accelerate structural change
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