Judul: Infeksi alami virus rabies pada anjing: studi morfopatologi dan imunohistokimia
Abstrak: Rabies is a zoonotic disease that remains a big problem in public health sector in Indonesia. The pathomorphological and antigen distribution of street rabies virus infection of the dogs brain from endemic area in Indonesia need for further investigation. The aim of this study was to describe macroscopical, histopathological and antigen distribution of rabid dogs which is infected with rabies virus naturally. Fourteen brains of stray rabid dogs from Disease Investigation Centre Bukittinggi area were used as samples. Conformatory diagnosed based on direct fluorescence antibody technique test. Hyperemic meningeal blood vessels were consistently found in all samples, sometimes associated with multiple ptechie and cerebral edema. Histopathological changes showed mild non-suppuratif meningoencephalitis with perivascullar cuffing surrounded by lymphocyte cells, associated with gliosis. Negri bodies were found in neuron cytoplasms in all samples mainly localized in pyramidal cells of cornua ammons of hippocampus and cerebral cortex, while neuronal degeneration and necrosis were mild. Viral antigens localized in perikaryon extending along the dendrites and axon and mostly localized on pyramidal cells of hippocampus, talamus and frontal lobes of cerebral cortex. Rabies antigen were also detected in epithelial cells of mucogenic acini of mandibulary glands and mildly in granular of striated duct of luminal parotidal glands. This study suggested that frontal lobes of cerebral cortex and mandibulary glands could be used as samples for rabies test in laboratory besides hippocampus.
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Judul: Rabies di sumatra utara tinjauan masalah dan penanggulanganya
Abstrak: Rabies adalah penyakit akut pada susunan syaraf pusat, menyerang manusia dan hewan berdarah panas, biasa ditularkan lewat gigitan. Berbagai masalah dapat ditimbulkan oleh ra- bies, baik masalah ekonomi maupun psikologis. Kerugian eko- nomi terjadi sebab penambahan biaya untuk vaksinasi ternak, biaya pencegahan dan pengobatan pada manusia serta mengham- bat tourisme. Sedang masalah psikologis timbul sebab ada- nya kegelisahan dan rasa takut pada masyarakat jika ada wa- bah di sekitarnya, karena sekali gejala kelihatan, maka kematian selalu merenggutnya. Sebelum mati biasanya ditan- dai dengan gejala khas yaitu lebih agressif dan paralise susunan syaraf pusat. Disamping itu adanya bahaya encepha- litis post vaccinal (radang otak setelah vaksinasi) sebab vaksin terbuat dari jaringan otak, membuat masyarakat serba salah. Rabies terdapat di sebagian besar bumi ini. Karena itu setiap negara memberi nama tersendiri untuk rabies, antara lain: Hydrophobia, Lyssa (Ingg), La Rage (Pr), Tolwut (Germ) Rabia (Sp). Tetapi negara-negara seperti Inggris, Austra - lia, Swedia, New Zealand, dll, dinyatakan bebas rabies. Rabies atau penyakit anjing gila, sudah lama ditemukan di Indonesia, kurang lebih 100 tahun lalu. Kejadian pertama...
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Judul: Metrik Einstein (Anti-) Self-Dual Berdimensi Empat dengan Metode Cartan
Abstrak: Gravitational field equation can be formulated in differential forms (differential geometry), which describes gravity as a manifestation of the curvature of space-time. Curvature of space-time is characterized by a metric that satisfies the gravitational field equation. With differential forms it can be formulated the (anti-) self-dual Einstein equation, which is a modification of the Cartan structure in (anti-) self-dual basis. Calculation of (anti-) self-dual metric with (anti-) self-dual Einstein equation is simpler than the calculation using Christoffel symbols.
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