Judul: Indonesian Jamu Herbs (Ijah) Web Server: Prediksi Interaksi Senyawa-Protein dan Analisi Efek Sinergis Senyawa.
Abstrak: Jamu merupakan obat herbal khas Indonesia yang diracik dari tumbuhtumbuhan yang dianggap mempunyai khasiat dalam menyembuhkan penyakit. Salah satu tools dalam pengembangan Jamu di Indonesia adalah IJAH web server. Sistem ini memanfaatkan data senyawa, protein, dan interaksi antar keduanya dari basis data yang tersebar di Internet. Penelitian ini bertujuan membuat model prediksi formula Jamu dan melakukan analisis efek sinergi senyawa penyusun formula Jamu. Bipartite Local Model Network Interaction-Profile Inferring (BLMNII) digunakan untuk memprediksi sekaligus melengkapi interaksi antara senyawa dan protein dalam jejaring formula Jamu, sedangkan Network Target-based Identification of Multicomponent Synergy (NIMS) digunakan untuk analisis efek sinergis antar senyawa. Model hasil BLM-NII yang telah dibuat mempunyai Area Under Precission-Recall Curve (AUPR) sebesar 0.70. NIMS telah diimplementasikan pada IJAH web server dan kombinasi terbaik dari dua senyawa untuk penyakit Diabetes mellitus dicapai oleh senyawa Glipizide dan Mitiglinide dengan skor sinergi 0.45.
Keyword: BLM-NII, Jamu, NIMS, obat herbal, prediksi

Judul: Pengembangan Modul Sistem Prediksi Formula Jamu pada Ijah Berdasarkan Aktivitas Farmakologi dan Target Khasiat Tertentu
Abstrak: Indonesia adalah salah satu negara dengan jumlah spesies tanaman herbal yang tinggi. Tanaman-tanaman herbal ini memiliki potensi untuk dapat digunakan sebagai bahan racikan pengobatan alternatif yaitu jamu. Formulasi khasiat jamu telah dilakukan pada beberapa penelitian menggunakan network pharmacology yang menghubungkan tanaman dan penyakit. Penelitian dalam memprediksi interaksi senyawa tanaman dan protein untuk membuat formula jamu telah diimplementasikan pada situs prediksi formula jamu Ijah. Formula jamu pada umumnya mengandung karakteristik analgesik, anti-inflamatori, antibakteri, dan aktifitas target. Situs Ijah belum menggunakan karakteristik tersebut untuk melakukan prediksi formula jamu terhadap senyawa tanaman. Hasil penelitian ini berupa sistem formulasi jamu baru secara molekular dengan senyawa yang mengandung karakteristik analgesik, anti-inflamatori, antibakteri dan, aktifitas target. Pada penelitian ini didapatkan daftar tanaman yang mengandung senyawasenyawa herbal dengan struktur yang mirip untuk formulasi jamu pengganti obat sintetik.
Keyword: analgesik, antibakteri, anti-inflamatori, jamu

Judul: Biology and ecology of the buffalo fly, haematobia exigua de meijere (diptera:muscidae)
Abstrak: The life history of the buffalo fly was observed at room temperature of 27°-29.5°C and at a relative humidity of 48-68 percent. The eggs hatched after 17-22 hours, with an average of 18 hours. First instar larvae measured 1.25 + 0.16 mm long and 0.27 + 0.037 mm wide. reach the second larval stage. It took 6-12 hours to the second instar larvae measured 2.676 +0.187 mm long and 0.353 +0.028 mm wide. The second instar took about 12-24 hours to reach the third larval stage. The third instar measured 6.833 + 0.189 mm long and 0.919 + 0.051 mm wide. It took about 2-3 days for the third instar to become pupae. Duration of the pupal stage was about 5-7 days before the adults emerged. Under laboratory condition, the buffalo fly completed its life cycle in 9.5 to 10.5 days, whereas under field condition it took 9-14 days with an average of 10.5 days. The growth ratio which was based on the measurements of the cephalo-pharyngeal skeleton of each instar was 1.797. The preoviposition period was 8-12 days and mating usually occurred on the 6th or 7th day. The longevity of the male was 29 days, whereas it was 32 days in the female. The range of egg production under laboratory condition was between 20-139 per female fly. The belly and hind legs of the carabao were the most preferred habitat either during cloudy and cool dry or shiny and warm day. When the weather was clear and the carabao was in the shade, the flies tended to be more distributed particularly on the shoulder, dewlap, back and horns. The carabaos had relatively fewer Musca sp. and Stomoxys calcitrans than cattle; never the less carabaos had a higher infestation of buffalo fly than cattle. Oviposition occured either during the day or night but the buffalo flies were more active during the night than in the day time. The effect of various lengths of exposure time of manure in relation to the oviposition was profound. observed, the maximum number of the buffalo flies was occurred when the dung was exposed for 30 minutes. With increasing time of exposure the number and variety of insects also increase. It was evident that Sepsidae and psychodidae were the most dominant insects emerging from the dung. The number of buffalo flies also increased with increasing
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