Judul: Fractionation of Bangle Essential Oil (Zingiber purpureum) as Aromatherapy for Antiobesity
Abstrak: Bangle is one of aromatic plants which contains of essential oil. The aims of this research were to find essential oil from bangle rhizomes and fractions having potency as aromatherapy for antiobesity. The essential oil contained in the rhizome isolated using distilation method were 0.38-0.91% (v/w) based on wet weight. The potency of compound in crude essential oil, fraction 1, and fraction 4 as aromatherapy for antiobesity was tested in vivo on male Sprague-Dawley rats. Inhalation of crude essential oil, fraction 1, and fraction 4 showed lower response to body weight gain of rats than positive control group (cholesterol fed). Among the three inhalated groups, the rats inhalating fraction 4 had the lowest response to body weight gain, i.e. 37.34% (w/w). Based on analysis of terpenes by gas chromatography-mass spectrometry (GC-MS), the dominant compound in bangle essential oil and in fraction 4 is terpinene-4-ol, indicating that the compound is potential as an aromatherapy for antiobesity.
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Judul: Fractionation of Active Components from Curcuma xanthorrhiza Essential Oil as Aromatherapy for Antiobesity Using In Vivo Analysis
Abstrak: The objectives of this research are to separate constituents of temulawak (Curcuma xanthorrhiza) essential oil and to evaluate their active components as aromatherapy for antiobesity using in vivo analysis. Fractionation of temulawak essential oil using silica gel column chromatography (gradient elution) produced 23 fractions. The activity of fraction 3 (F3), fraction 4 (F4), and the crude oil as aromatherapy for antiobesity were evaluated by in vivo analysis using male Sprague-Dawley rats. The in vivo test was performed in 5 groups (10 rats for each group). Group 1 was a negative control which consumed normal diet, group 2 consumed high cholesterol diet without treatment, group 3, 4, and 5 consumed high cholesterol diet with treatment inhalation of crude oil 1% (v/v), F3 1% (v/v), and F4 1% (v/v) which consist of β-elemenone as the main component, respectively. Group 5 showed an increasing body weight about 29.54% (w/w) close to that of group 1 (26.39% w/w), the lowest number of feed consumption (165.20 g), and their fecal output was 323 g. In addition, group 5 showed the highest liver weight (10.92±0.56 g) and the lowest parametrical fat weight (2.37±0.51 g). These results conclude that β-elemenone of temulawak essential oil is potential as aromatherapy for antiobesity.
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Judul: Closed Knight’s Tour pada Papan Catur Berbentuk Persegi Panjang dengan Ukuran Maksimal 8 × 8
Abstrak: Closed Knight’s Tour merupakan langkah kuda yang mengunjungi setiap kotak pada papan catur tepat satu kali dengan langkah kuda berawal dan berakhir pada kotak yang sama. Graf yang terbentuk dari closed knight’s tour dinotasikan sebagai graf G(m,n), dengan m adalah banyaknya baris dan n adalah banyaknya kolom. Graf tersebut memuat Hamiltonian cycle. Sebuah graf terhubung G adalah graf bipartite jika dan hanya jika graf tersebut tidak memiliki cycle dengan panjang ganjil. Papan catur yang memenuhi syarat cukup untuk memiliki closed knight’s tour adalah papan catur berukuran 5 × 6, 5 × 8, 6 × 6, 6 × 7, 6 × 8, 7 × 8, dan 8 × 8.
Keyword: bipartite, closed knight’s tour, hamiltonian cycle, knight’s tour, teori graf