Judul: Pengetahuan tentang Manfaat Kesehatan, Aktivitas Inhibisi Enzim α‒Glukosidase, dan Uji Toksisitas Minuman Binahong (Anredera cordifolia).
Abstrak: Diabetes mellitus merupakan kondisi klinis yang ditandai dengan hiperglikemia atau peningkatan kadar glukosa di dalam darah. Inhibitor enzim α‒glukosidase digunakan untuk mengontrol keadaan tersebut, terutama bagi penderita diabetes mellitus tipe 2. Penelitian ini bertujuan untuk menganalisis pengetahuan masyarakat sebanyak 50 responden mengenai manfaat kesehatan binahong, mengidentifikasi kandungan fitokimia dan kandungan total flavonoid, aktivitas inhibisi α‒glukosidase serta uji toksisitas dari minuman binahong. Hasil penelitian menunjukkan bahwa manfaat kesehatan yang banyak diketahui adalah untuk mengobati luka dan penyakit diabetes mellitus. Daun binahong direbus dalam 1000 ml air dengan jumlah daun yang berbeda-beda yaitu 7, 9, 11, dan 13 lembar. Analisis aktivitas inhibisi α‒glukosidase menunjukkan keempat perlakuan tidak menunjukkan perbedaan yang signifikan (p = 0.012), aktivitas inhibisi tertinggi yaitu sebesar 70.245% dimiliki oleh minuman binahongdengan jumlah daun sebanyak 9 lembar, dan aktivitas terendah ditunjukan oleh air rebusan dengan jumlah daun paling banyak yakni sebesar 59.379%. Berdasarkan uji fitokimia, komponen kimia yang terkandung dalam air minuman binahong adalah golongan alkaloid, saponin, fenolik, flavonoid, dan glikosida. Kandungan total flavonoid tertinggi didapat dari dengan jumlah daun sebanyak 9 lembar sebesar 9.039 g/100 g. Uji toksisitas dilakukan dengan metode Brine Shrimp Lethality Test. Hasil perhitungan uji toksisitas dengan nilai LC50, keempat perlakuan memiliki aktivitas toksik.
Keyword: α‒glukosidase, binahong, flavonoid, manfaat kesehatan, toksisitas

Judul: Komponen Sitotoksik dari Daun Binahong (Anredera. cordifolia) lBerbasis Analisis Larva Udang
Abstrak: Fractionation and identification of cytotoxic components from binahong (Anredera cordifolia) leaves based on Artemia salina Leach analysis have been carried out. Air-dried binahong leaves were macerated in ethanol as solvent. The ethanol crude extract was further partitioned with n-hexane, dichloromethane, and n-butanol. Toxicity test with A. salina showed that the n-butanol extract was the most toxic with 50% lethal concentration (LC50) of 494μg/mL. Fractionation of the n-butanol extract by using column chromatography and gradient elution with n-hexane-chloroform-methanol resulted 5 fractions. Fraction 4 was the most toxic with LC50= 23.4μg/mL, and gave single spot in thin layer chromatography with chloroform-methanol (7:3) as eluent. Phytochemistry test results and analysis of Fourier transform infrared spectrum showed that the active components of the fraction had carboxyl, aromatic ring, and ester groups. Gas chromatography-mass spectrometry analysis obtained bis-2-ethylhexyl-1,2-benzenedicarboxylate as the main component (79.29%), along with oleic acid (5.30%) and palmitic acid (4.78%).
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Judul: Dynamics Model for Rural and Urban Economic Growth
Abstrak: Lewis theory of structural change has focused on mechanisms that allow countries to transform their domestic economic structure to a more modern economy. The proposed model deals with the mechanism of interaction between rural and urban Economic. This model is concerned with the process of labor transfer from rural to urban areas. This study aims to model the dynamics of economic growth in rural and urban areas, including determining the equilibrium solution and to carry out simulation of the model. The simulation results show that the transfer of labor from rural to urban areas will increase the rate of change of capital so that structural changes can be realized. In addition, increased propensity to save in rural areas will also accelerate structural change
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