Judul: Pengaruh Social Media Marketing terhadap Proses Keputusan Pembelian pada Produk Susu Mbok Darmi
Abstrak: Kemajuan teknologi internet menyebabkan persaingan bisnis semakin ketat, hal ini mendorong para pelaku usaha untuk terus melakukan berbagai upaya dalam memasarkan produknya. Salah satu upaya pemasaran yang efektif adalah dengan meningkatkan pemasaran melalui media sosial. Susu Mbok Darmi merupakan usaha kuliner yang memanfaatkan media sosial dalam pemasarannya. Penelitian ini bertujuan untuk menganalisis pengaruh social media marketing terhadap proses keputusan pembelian pada produk Susu Mbok Darmi. Penelitian ini dilaksanakan di outlet Susu Mbok Darmi pada bulan Desember 2022 sampai dengan Juni 2023. Jenis data yang digunakan bersumber dari data primer dan data sekunder. Penentuan sampel pada penelitian ini menggunakan metode convenience sampling. Jumlah sampel dalam penelitian ini adalah 220 responden yang ditentukan berdasarkan teori Roscoe. Metode yang digunakan yaitu analisis deskriptif dan analisis Structural Equation Modelling-Partial Least Square (SEM-PLS). Hasil dari penelitian ini menunjukkan bahwa keempat variabel dari social media marketing yang terdiri dari context, communication, collaboration, dan connection berpengaruh secara positif dan signifikan terhadap proses keputusan pembelian pada produk Susu Mbok Darmi.
Keyword: Proses Keputusan Pembelian, SEM-PLS, Social Media Marketing

Judul: Effectiveness of Digital Marketing Communications by UMKM Susu Mbok Darmi using "AIDA" Approach Analysis
Abstrak: Berkembangnya industri makanan dan minuman diikuti tingginya pengeluaran konsumsi masyarakat akan kebutuhan makan dan minuman menjadikan sektor ini sebagai peluang bisnis. Tujuan penelitian ini adalah untuk mengkaji bagaimana efektivitas komunikasi pemasaran yang diterapkan UMKM Susu Mbok Darmi dengan pendekatan “AIDA”. Penelitian dilaksanakan dengan pendekatan kuantitatif dan kualitatif. Data primer diperoleh dari 100 responden yang memenuhi kriteria dan dipilih menggunakan teknik nonprobability sampling dan convenience sampling. Data penelitian diolah menggunakan uji korelasi Rank Spearman dan uji Chi-Square. Hasil penelitian menunjukkan mayoritas konsumen adalah generasi Z dengan usia di bawah 29 tahun. Karakteristik konsumen tidak berkorelasi nyatadengan efektivitas komunikasi pemasaran. Sementara itu, terdapat hubungan positif antara komunikasi pemasaran digital dengan efektivitas komunikasi pemasaran. Komunikasi pemasaran melalui media digital cukup efektif dalam menumbuhkan kesadaran dan memunculkan keinginan konsumen, tetapi belum efektif dalam menimbulkan rasa tertarik dan mendorong responden untuk melakukan pembelian., The development of the food and beverage industry followed by high public consumption expenditure on this area capable to create business opportunity. The research aims to examine the effectiveness of the marketing communications implemented by UMKM Susu Mbok Darmi using the "AIDA" approach. The research employs quantitative and qualitative approaches. The primary data was gathered from the 100 respondents that were chosen through nonprobability sampling and convenience sampling techniques. A Rank-Spearman correlation test and Chi-Square test were used to analyze the data. The research results show that most consumers are Z generation under 29 years old. Consumer characteristics do not have a significant correlation with the effectiveness of marketing communications. Meanwhile, there is a positive correlation between digital marketing communications and the effectiveness of marketing communications. Marketing communication activities through digital media are quite effective in raising awareness and generating consumer desire but are not yet effective in generating interest and encouraging respondents to make purchases.
Keyword: AIDA, komunikasi pemasaran digital, Konsumen, UMKM

Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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