Judul: Analisis Persepsi Nilai Anak dan Perilaku Investasi Waktu pada Anak (Kasus di Desa Situ Udik, Kecamatan Cibungbulang, Kabupaten Bogor)
Abstrak: The purpose of this research were to describe the value of children and time investment of parents in the village area and to analyze the effect of family characteristic and value of children toward time investment of parents to children at Situ Udik Village, Cibungbulang Sub District, District of Bogor. This research involved 60 families respondent which have child under five years old that split into two social economic status: poor (30 families) and not poor (30 families), base on BKKBN’s family welfare phasing.The sample were interviewed by using structure questionnaire. The result of this research showed that there are no significant different on the perception of children value between poor and not poor family, as well as time investment of parents to children. Regression analyzis showed that time investment of parents to children influenced by mother’s education and value of children.
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Judul: Pengaruh Nilai Anak Terhadap Perilaku Investasi Anak pada Keluarga Miskin dan Tidak Miskin
Abstrak: Children investment behavior is on important factor to reach qualified children outcomes. This research was to analyze influence of value of children on children investment behavior of poor and non-poor family, involving 28 poor family and 27 non-poor family. Samples were famillies that have children in 1st grade and 2nd grade elementary school that were chosen randomly from the population who lived in Kotabatu Village, Ciomas Sub District, Bogor District. Data were collected by interviewing the mothers and using questionnaire. This research showed that there was positive and significant influence of wife’s education level, family poverty category, and social value of children on children investment behavior. Furthermore, analysis result showed that the number of schooled children and economic value of children had positive and significant influence on children investment expenditure allocation
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Judul: Pemurnian dan karakterisasi protein inhibitor RNA helikase virus hepatitis C
Abstrak: Hepatitis C virus (HCV) infection is the second most common chronic viral infection in the world with global prevalence. This infection is contribution to chronic hepatitis and liver cirrhosis, often leading to hepatocellular carcinoma. There is no effective drug and vaccine available against HCV. The current standard treatment, a combination of pegylated interferon-α with ribavirin, is limited by its suboptimal response rate in a significant patient population, side effects, and affordability. Therefore, development of effective drug is needed. One approach to find out the candidate of antiviral drug is to discover the inhibitor of enzyme that essential for virus replication, such as RNA helicase. Streptomyces chartreusis 5-095 produce the inhibitor of HCV RNA helicase. The aim of this study was to purify the protein inhibitor which has inhibition activity against ATPase activity of RNA helicase HCV from S. chartreusis 5-095. The supernatant of culture S. chartreusis 5-095 exhibited high inhibiton activity against ATPase activity of RNA helicase HCV (approximately 72%) at 10 days of incubation. The extracellular protein inhibitor was partially purified by procedures of precipitation with ammonium sulfate to 65% saturation and gel filtration (Sephadex G50) using methanol water solution (4:6) as an eluen. The purity of protein inhibitor was monitored by SDS PAGE. The protein inhibitor showed a relative molecular mass were estimated to be 14 kDa and increased the purity 23,08 fold than those of the crude protein. The specific activity and IC50 after purification were 13,1338 U/mg and 0,0767 mg/mL, respectively. The activity of purified protein inhibitor showed its stability over pH range from 5-8 and optimum at pH 7,4. The inhibition activity showed its stability up to 70% at temperature 100 oC. The purified protein inhibitor relatively stable its activity at storage in the range of -20 oC to room temperature for 35 days.
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