Judul: Studi Kemampuan Netralisasi Antibodi Anti AI H5N1 Asal Induk Dalam Kuning Telur Ayam Yang Divaksinasi Berbagai Vaksin AI H5N1 Komersial Terhadap Virus AI H5N1
Abstrak: The research was designed to study the capability of antibody anti H5N1 Avian Influenza from egg yolk to neutralize H5N1 AIV. Twenty five hens were divided into five groups, one group as a control group were unvaccinated and four other groups were vaccinated with H5N1 AI inactive vaccine produced by several Indonesia vaccine company. Four H5N1 AI inactive vaccine code VS, VC, VV and VM were vaccinated twice for each group with a month, interval. Group 2 were vaccinated with vaccine code VS, group 3, 4, 5 were vaccinated by vaccine code VC, VV and VM. A week after second vaccination the egg were collected and analyzed the antibody titer against H5N1 AIV by heamagglutination test using H5N1 AIV field isolates as standard virus (Nagrak (2009) and Lawang (2010)). Egg yolk which contains high antibody titer (above 26) were collected and tested against H5N1 AIV field isolates (Nagrak (2009) and Lawang (2010)) by serum neutralization test. The result showed that H5N1 AIV Nagrak (2009) isolate were neutralized by antibody anti H5N1 AIV from egg yolk produced by hens vaccinated with VS,VC,VV and VM, but Lawang (2010) isolate were only neutralized by antibody anti H5N1 AIV from egg yolk produced by hens vaccinated with VS, VC and VM. It is concluded that hens which were vaccinated with H5N1 AI inactive vaccine were able to protect their off spring against H5N1 AIV from the field by transferred maternal antibody trough the egg yolk with titer above 26 Keywords : Maternal Antibody, Antigen, Vaccine, Egg yolk. .
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Judul: Kemampuan Netralisasi Antibodi Spesifik Avian Influenza H5 Terhadap Beberapa Virus H5N1 Isolat Lapang
Abstrak: Avian Influenza (AI) is well known as Avian flu, Fowl pest, Fowl plaque, or Flu burung, caused by influenza virus type A. This virus is belonged to Orthomyxoviridae and could infect many kind of species such as bird, pig, horse, cat, as well as human. Vaccination is applied to control the disease using inactivated vaccine, which induced the specific antibody against H5 antigen. Passive immunization using specific antisera against H5 antigen is thought to be usefull in controlling the disease especially in the treatment of infected host. In this experiment the neutralization ability of specific antisera against H5 were studied using various field viral isolates subtype H5N1. Antisera was developed in Cavia porcellus which vaccinated with AI subtype H5N1 in activated vaccine. The titre of antisera obtained is 28 used HI test. Four AI virus subtype H5N1 isolates from 2003 to 2006 agains viral were we as tested virus. The neutralization test showed that the sera were able to neutralizing 10 4 EID50 AI virus H5N1 with neutralization index range between 1,1– 1,3. The result indicated that the specific antisera had the neutralization potency to the field virus.
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Judul: Bifurkasi Hopf pada Model Siklus Bisnis Kaldor Kalecki tanpa dan dengan Waktu Tunda
Abstrak: Business cycle model is one of dynamical system models in economic. One of the business cycles model is Kaldor-Kalecki model. Kaldor-Kalecki business cycle model that is written in delayed defferential equations, is a business cycle model that involves gross product and capital stock of a company. In this paper Kaldor-Kalecki business cycle model is analyzed using both nondelay and delay in time of capital stock. By Taylor expansion for the time delayed model, an analysis of stability around the fixed points has been done. Furthermore, by using Hopf bifurcation theorem, it can be shown that there exists periodic orbits and limit cycle. In the nondelayed model, changing the parameter of goods market could lead to the occurrence of Hopf bifurcation and the existence of limit cycle. Similarly, for the delayed model, it has been shown that changing the time delay parameter may result in the occurrence of Hopf bifurcation and limit cycle.
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