Judul: Analisis Harmonik Gelombang Pasang Surut dan Gelombang Permukaan di Teluk Palabuhanratu
Abstrak: Ocean waves such as tides and surface waves affect many activities in marine and coastal area. The purposes of study are to analyze tidal harmonic constituents and wave energy density along with it association with seasonal pattern. Tidal and surface waves measurement held around Sangrawayang, Palabuhanratu using RBR TWR-2050. Recorded data processed utilizing harmonic analysis least square method for tidal wave and distribution and seasonal variability of surface wave. Tidal harmonic analysis show a mixed tides prevailing semidiurnal with Formzahl number is 0.89. Analysis of surface waves shows the wave height ranged between 0.17 - 0.77 meter with dominant period between 10 -15 second categorized as swell. Comparison with Jason-2’s sea surface wave shows there is an association with a seasonal pattern in which the east monsoon wave height trend is higher than the west monsoon.
Keyword: seasonal pattern., harmonic analysis, surface waves, tidal, Palabuhanratu

Judul: Karakteristik Oseanografi dan Estimasi Indeks Kesehatan Laut di Kawasan Teluk Palabuhanratu dan Sekitarnya
Abstrak: Teluk Palabuhanratu dikenal sebagai salah satu daerah utama penangkapan ikan di perairan Selatan Jawa yang memiliki potensial perikanan pelagis dan sumber daya laut lainnya. Wilayah ini berpotensi terancam oleh kualitas air yang dapat mempengaruhi kesehatan lingkungan laut. Tujuan dari penelitian ini adalah mendeskripsikan karakteristik oseanografi secara spasio-temporal, variasi volume transpor, serta tren dan estimasi indeks kesehatan laut berdasarkan parameter oseanografi di Teluk Palabuhanratu. Dataset rataan harian dari keluaran model INDESO dan MARINE COPERNICUS (2008-2019) digunakan untuk penelitian ini. Data deret-waktu tersebut divalidasi dan dianalisis dengan metode Empirical Orthogonal Function (EOF), metode Power Spectral Density (PSD), serta estimasi tren dan indeks kesehatan laut. Hasil penelitian menunjukkan pola arus pada musim barat (musim timur) bergerak mendekati (menjauhi) teluk dengan pola sebaran suhu yang semakin rendah (tinggi) ke arah laut lepas sedangkan salinitas sebaliknya. Variasi suhu pada musim barat lebih tinggi (rendah) dibandingkan pada musim timur dan saat terjadi IOD negatif suhu lebih rendah. Struktur vertikal arus zonal pada musim barat (musim timur) arus permukaan dominan bergerak ke arah timur (ke arah barat), tetapi pada kedalaman 20-100 m pada musim barat (musim timur) terdapat arus yang bergerak ke arah barat (ke arah timur). Tren parameter selama 12 tahun menunjukan pola penurunan pada parameter suhu dan oksigen, sedangkan pada parameter lainnya mengalami kenaikan. Estimasi indeks kesehatan laut memiliki nilai 0.66 yang tergolong dalam kondisi cukup baik., The Palabuhanratu Bay is well known as one of the main fishing regions in the southern Java waters that has potential pelagic fisheries and other marine resources. This region may be potentially threatened by suitable water quality that may affects the health of the marine environment. The aim of this research is to describe the spatio-temporal oceanographic characteristics, transport volume variability, as well as trends and estimation of marine health indices based on oceanographic parameters in Palabuhanratu Bay. Daily averaged datasets from INDESO and MARINE COPERNICUS model outputs (2008-2019) were used for this study. The time-series data were validated and analyzed by Empirical Orthogonal Function (EOF) method, Power Spectral Density (PSD) method, and trend estimation and ocean health index. The results showed that the current pattern in the west season (east season) moves closer to (away from) the bay with a lower (higher) sea water temperature distribution pattern towards the open sea while salinity is the opposite. Variability of seawater temperature in the western season are higher (lower) than in the eastern season and during negative IOD temperatures are lower. The vertical structure of zonal currents in the west season (east season) dominant surface currents move eastward (westward), but at a depth of 20-100 m in the west season (east season) there are currents that move westward (eastward). The trend of parameters for 12 years shows a decreasing pattern in temperature and oxygen parameters, while other parameters have increased. The estimated ocean health index has a value of 0.66, which is classified as in fairly good condition
Keyword: Analisis data deret-waktu, dataset INDESO, indeks kesehatan laut, karakteristik oseanografi, Teluk Palabuhanratu

Judul: Differential Leukocytes in Mice (Mus muscullus) after Amyloid Beta Aβ40 and Aβ42 Immunization as a Marker of Alzheimer’s Disease.
Abstrak: Alzheimer merupakan penyakit neurodegeneratif yang bersifat irreversibel dan progresif yang terkait dengan perubahan sel-sel saraf, sehingga menyebabkan kematian sel otak dan terjadinya demensia. Pengamatan terhadap diferensial leukosit dapat membantu dalam mendiagnosa penyakit ini dengan tepat. Penelitian ini bertujuan mengetahui gambaran diferensial leukosit pada mencit terhadap respon imunisasi amyloid beta Aβ40 dan Aβ42. Penelitian ini menggunakan 22 ekor mencit (Mus muscullus) Balb/c jantan dan betina dengan berat badan 20-35 gr. Mencit dibagi menjadi tiga kelompok yaitu, kelompok mencit kontrol, kelompok mencit vaksinasi antigen amyloid Aβ40 dan kelompok mencit vaksinasi antigen amyloid beta Aβ42. Sampel darah dimabil melalui vena coccygea sebanyak 0,5 ml setiap mencit. Sampel darah diambil pada hari ke-0, 14 dan 24 setelah diimunisasi. Hasil menunjukkan kelompok mencit yang diimunisasi amyloid beta 40 (Aβ40) dan amyloid beta 42 (Aβ42) menyebabkan peningkatan jumlah limfosit dan neutrofil yang signifikan, sedangkan kelompok mencit kontrol tidak menunjukkan perubahan leukosit yang signifikan. Berdasarkan hasil pengamatan dapat disimpulkan bahwa pemberian imunisasi antigen amyloid beta Aβ40 dan Aβ42 pada mencit tidak memengaruhi jumlah basofil, eosinofil, neutrofil batang serta monosit., Alzheimer's is an irreversible and progressive neurodegenerative disease associated with changes in nerve cells, leading to brain cell death and dementia. Observation of differential leukocytes can help in diagnosing the disease precisely. This study aims to find out the differential picture of leukocytes in mice against amyloid beta Aβ40 and Aβ42 immunization responses. This study used 22 mice (Mus muscullus) Balb / c male and female with a weight of 20-35 grams. Mice were divided into three groups, namely, the control mice group, the Aβ40 amyloid antigen vaccination mice group and the Aβ42 amyloid beta antigen vaccination mice group. Blood samples are taken through the coccygea vein as much as 0.5 ml per mice. Blood samples are taken on days 0, 14 and 24 after immunization. Results showed the mice group immunized amyloid beta 40 (Aβ40) and amyloid beta 42 (Aβ42) caused a significant increase in lymphocyte and neutrophil counts, while the control mice group showed no significant leukocyte changes. Based on the observations, it can be concluded that immunization of amyloid beta Aβ40 and Aβ42 antigens on mice does not affect the number of basophils, eosinophils, bar neutrophils and monocytes.
Keyword: Alzheimer, Diferensial leukosit, Amyloid beta, Mencit, Alzheimer's, differential leukocytes, amyloid beta, mice