Judul: Potensi dan Pemanfaatan Jasa Lingkungan Kawasan Karst Gua Gudawang
Abstrak: Gudawang Cave Karst Area is one of the karst area that are located in Bogor. This karst area has the ecosystem service potential that aren’t maximally utilized. This happen because there's no information about what ecosystem service that owned by the manager. This condition leading to the need for identification ofecosystem service potential and its utilization by local community. Research was done at March to June 2013 through field observation, interview, and literature study. The result of this research indicated that from 10 identified cave all of them were natural habitat of wildlife as shown by 19 wildlife species that were discovered inside the cave. All of them were also potentialfor tourism because of the different characteristic in each caveidentified. As many as 8 from them are potential for carbon dioxide absorptionand water supply. Only 3 of all the identified cave that have beenmanaged as tourism object and only 1 of all the identified cave has been used as water supply for local community.
Keyword: 

Judul: Potensi dan Manajemen Bahaya Bagi Keselamatan Pengunjung di Gua Seplawan Purworejo Jawa Tengah
Abstrak: Gua Seplawan sebagai wisata gua di Purworejo, memanfaatkan formasi eksokarst dan endokarst sebagai daya tarik utama; namun terdapat potensi bahaya yang signifikan bagi pengunjung dan pengelola. Perbedaan karakteristik bahaya antara eksokarst dan endokarst memerlukan manajemen risiko yang efektif untuk mengurangi atau menghindari dampak merugikan. Penelitian ini bertujuan menginventarisasi potensi bahaya dan merancang manajemen risiko wisata Gua Seplawan. Metode penelitian meliputi observasi lapangan, inventarisasi potensi bahaya, studi literatur, wawancara dengan pengelola dan pengunjung. Data dianalisis menggunakan modifikasi panduan UNEP 2008 dan NSPA 2008. Potensi bahaya fisik pada area eksokarst meliputi tangga licin dan ancaman tanah longsor, sementara tidak ditemukan bahaya biologis. Potensi bahaya fisik endokarst mencakup jalanan licin, tanah lumpur, risiko banjir, stalaktit rendah, lorong sempit, dan kondisi suhu serta kelembapan yang ekstrem; bahaya biologi endokarst yaitu kelelawar dan guano; bahaya antropogenik di kedua area adalah membawa beban berlebihan, berlari di tangga, memasuki gua ketika hujan, menginap di gua, tidak menggunakan perlengkapan gua yang sesuai, dan mendekati tepi jurang. Rekomendasi manajemen risiko yaitu edukasi ke pemandu dan pengunjung, penambahan tali pengaman pada jalur gua, serta pemasangan papan peringatan di area stalaktit rendah, lorong sempit, hunian kelelawar, dan berlumpur. Kata kunci: Endokarst, NSPA 2008, susur gua, UNEP 2008, wisata gu, Seplawan Cave is a cave tourism in Purworejo that leverages of exokarst and endokarst formations as its main attraction; however, there are significant potential hazards for both visitors and management. The differences in the characteristics of hazards between exokarst and endokarst require effective risk management to mitigate or avoid adverse impacts. This study aims to inventory potential hazards and design a risk management plan for Seplawan Cave tourism. The research methods include field observations, hazard inventory, literature review, and interviews with managers and visitors. Data is analyzed using modified guidelines from UNEP 2008 and NSPA 2008. Physical hazards in the exokarst area include slippery stairs and landslide threats, while no biological hazards are found. Physical hazards in the endokarst area include slippery pathways, muddy soil, flood risks, low-hanging stalactites, narrow passages, and extreme temperature and humidity conditions; biological hazards in the endokarst area include the presence of bats and guano; anthropogenic hazards in both areas include carrying excessive loads, running on stairs, entering the cave during rain, staying overnight in the cave, not using appropriate caving equipment, and approaching cliff edges. Risk management recommendations include educating guides and visitors, adding safety ropes on cave routes, and installing warning signs in low-hanging stalactites, narrow passages, bat habitats, and muddy areas. Keywords: Cave exploration, cave tourism, endokarst, NPSA 2008, UNEP 2008.
Keyword: NPSA 2008, UNEP 2008, endokarst, Cave exploration, cave tourism

Judul: Differential Leukocytes in Mice (Mus muscullus) after Amyloid Beta Aβ40 and Aβ42 Immunization as a Marker of Alzheimer’s Disease.
Abstrak: Alzheimer merupakan penyakit neurodegeneratif yang bersifat irreversibel dan progresif yang terkait dengan perubahan sel-sel saraf, sehingga menyebabkan kematian sel otak dan terjadinya demensia. Pengamatan terhadap diferensial leukosit dapat membantu dalam mendiagnosa penyakit ini dengan tepat. Penelitian ini bertujuan mengetahui gambaran diferensial leukosit pada mencit terhadap respon imunisasi amyloid beta Aβ40 dan Aβ42. Penelitian ini menggunakan 22 ekor mencit (Mus muscullus) Balb/c jantan dan betina dengan berat badan 20-35 gr. Mencit dibagi menjadi tiga kelompok yaitu, kelompok mencit kontrol, kelompok mencit vaksinasi antigen amyloid Aβ40 dan kelompok mencit vaksinasi antigen amyloid beta Aβ42. Sampel darah dimabil melalui vena coccygea sebanyak 0,5 ml setiap mencit. Sampel darah diambil pada hari ke-0, 14 dan 24 setelah diimunisasi. Hasil menunjukkan kelompok mencit yang diimunisasi amyloid beta 40 (Aβ40) dan amyloid beta 42 (Aβ42) menyebabkan peningkatan jumlah limfosit dan neutrofil yang signifikan, sedangkan kelompok mencit kontrol tidak menunjukkan perubahan leukosit yang signifikan. Berdasarkan hasil pengamatan dapat disimpulkan bahwa pemberian imunisasi antigen amyloid beta Aβ40 dan Aβ42 pada mencit tidak memengaruhi jumlah basofil, eosinofil, neutrofil batang serta monosit., Alzheimer's is an irreversible and progressive neurodegenerative disease associated with changes in nerve cells, leading to brain cell death and dementia. Observation of differential leukocytes can help in diagnosing the disease precisely. This study aims to find out the differential picture of leukocytes in mice against amyloid beta Aβ40 and Aβ42 immunization responses. This study used 22 mice (Mus muscullus) Balb / c male and female with a weight of 20-35 grams. Mice were divided into three groups, namely, the control mice group, the Aβ40 amyloid antigen vaccination mice group and the Aβ42 amyloid beta antigen vaccination mice group. Blood samples are taken through the coccygea vein as much as 0.5 ml per mice. Blood samples are taken on days 0, 14 and 24 after immunization. Results showed the mice group immunized amyloid beta 40 (Aβ40) and amyloid beta 42 (Aβ42) caused a significant increase in lymphocyte and neutrophil counts, while the control mice group showed no significant leukocyte changes. Based on the observations, it can be concluded that immunization of amyloid beta Aβ40 and Aβ42 antigens on mice does not affect the number of basophils, eosinophils, bar neutrophils and monocytes.
Keyword: Alzheimer, Diferensial leukosit, Amyloid beta, Mencit, Alzheimer's, differential leukocytes, amyloid beta, mice