Judul: Kearifan Lokal Komunitas Kuta Dalam Pengelolaan Sumberdaya Air
Abstrak: Penelitian ini bertujuan untuk menggali dan menganalisis kearifan lokal komunitas Kuta dalam menjaga dan mengelola sumberdaya air; menganalisis peran pemimpin adat dalam proses ajar kearifan lokal; dan menggali strategi nafkah rumah tangga. Data dikumpulkan menggunakan kombinasi pendekatan kuantitatif dan kualitatif. Hasil penelitian menunjukkan, pertama, di komunitas Kuta berkembang norma perlindungan sumberdaya alam, dan norma kehidupan sehari-hari. Melalui budaya pamali (tabu, larangan) norma-norma tersebut mewujud dalam bentuk kearifan lokal perlindungan mata air dan hutan keramat. Kedua, di mata responden Ketua Adat dipandang sebagai pemimpin yang paling besar peranannya dalam memelihara kearifan lokal air dibanding Kuncen, Sesepuh, dan Lurah. Sementara dalam memelihara kearifan lokal hutan. Sesepuh dan Kuncen dipandang berperan lebih besar dibanding Ketua Adat dan Lurah. Secara keseluruhan Kuncen dan Sesepuh dipandang berperan lebih besar dalam memelihara kearifan lokal air dan hutan dibanding Ketua Adat, dan Lurah. Ketiga, dari berbagai luas penguasaan lahan, pendapatan rumah tangga responden dari sektor on farm, off farm, dan non farm dapat dikatakan tidak terlampau timpang. Pendapatan rumah tangga responden dengan luas penguasaan lahan <1 ha rata-rata mencapai Rp 2 juta per rumah tangga per bulan. Sementara pendapatan petani dengan penguasaan lahan >1 ha rata-rata mencapai Rp 3,3 juta per rumah tangga per bulan.
Keyword: kearifan lokal, proses ajar, pemimpin lokal, sumberdaya air, strategi nafkah

Judul: Kearifan Lokal dalam Pengelolaan Sumberdaya Air di Kampung Kuta (Desa Karangpaningal, Kecamatan Tambaksari, Kabupaten Ciamis, Jawa Barat)
Abstrak: Water is important resources to fulfill human needs. So, water resources must managed properly in order to maintain the sustainability of resources. Water resources management should adapt to each area’s characteristic because it has different local wisdom. Local wisdom not only as the features of a community, but also as the effort for ecological environment sustainability. The purpose of this research is to identify the form of local wisdom that existed in Kampung Kuta and identify local wisdom implementation in taking care of water resources sustainability. The method of this research is qualitative approach with descriptive research type. This descriptive research gives clear picture about phenomenon of local wisdom and its application of water resources management. Researcher uses methodologies triangulation that is deep interview, limited of perception shares, and observation. Research data is presented in the form of daily note and presented in direct citation. This research is conduct in the countryside of Karangpaningal, District of Tambaksari, Sub-Province of Ciamis, Province of West Java. The result of this research shows existence of Pamali as the form of local wisdom that defended society in by generations. The form of pamali that become obligatory tradition norm of society that is continuity of tradition house, enjoinment of dead body obsequies, enjoinment of well making, and continuity Hutan Keramat. The culture of pamali as the local wisdom in Kampung Kuta not experiences of transformation. This local wisdom are fixed defended and effective in arranging society life and nature. Pamali are alighted from old generation to the rising generation. Transfers of knowledge are conducted by mouth passed by stories and effective for permanence the local wisdom. Local wisdom implementation in water resources management seen from Pamali that prohibit society to make well. Pamali has given positive impact of water resources sustainability in Kampung Kuta. This condition are proved with the of appreciation Kalpataru in the case of environment sustainability in 2002. Water resources in Kampung Kuta are used in two functions that is to fulfill everyday need and for ritual tradition Nyipuh in Hutan Keramat.
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Judul: Pemeriksaan Histopatologi Cardiotoxicity Yang Diinduksi Jantung Pada Tikus Yang Diobati Dengan Doxorubicin Dan Cyclophosphamide
Abstrak: Cyclophosphamide is classified as an alkylating agent, whereas doxorubicin belongs to the anthracycline class, both of which are commonly employed chemotherapy drugs. Previous research has established that the choice of chemotherapy medications significantly impacts the development of cardiotoxicity. Myocarditis, characterized by inflammation of the myocardium, adversely affects the heart's electrical system and muscle cells, leading to impaired blood pumping capabilities. Consequently, the heart becomes more susceptible to clot formation, ultimately resulting in cardiac failure. The objective of this study was to observe, compare, and describe the lesions induced by two distinct chemotherapeutic drugs in rat models, utilizing normal heart tissue as the control. Routine Hematoxyline- Eosin (HE) staining was employed for histopathological assessments. Subsequently, the histopathological images were analysed descriptively and statistically using appropriate methods. The findings revealed that the diameter of myocardial cells remained unaffected by both doxorubicin and cyclophosphamide treatments, in comparison to the normal-control group. Histopathologically, both doxorubicin- and cyclophosphamide-treated groups exhibited multiple necrotic myocardial cells and focal infiltrations of mononuclear cells, predominantly macrophages and lymphocytes, between the myocardial cells. Furthermore, distinct pathological differences were observed between the doxorubicin- and cyclophosphamide-treated groups, with cyclophosphamide toxicity additionally presenting with pericarditis alongside myocarditis, in contrast to doxorubicin toxicity. In conclusion, these results demonstrate that the type of chemotherapeutic drugs employed leads to variations in the resulting lesions.
Keyword: Cardiotoxicity, chemotherapy, cyclophosphamide, doxorubicin, myocarditis