Judul: Gambaran Histopatologi Organ Limpa pada Kalong Asal Gorontalo
Abstrak: Acerodon celebensis and Pteropus hypomelanus are species of Chiroptera that lived at Gorontalo. Those species are known as fruit bats that has potential as reservoir host for several zoonosis cases. The aim of this study was to determine the health status of Gorontalo’s fruit bats through the overview histopathology of spleen. Nine samples were used in this research that consist of seven spleens of Acerodon celebensis and two spleens of Pteropus hypomelanus that had been fixed in a solution of Buffer Neutral Formalin 10%. Observations were made by looking at the state of the red pulp and white pulp by using three different staining is Hematoxylin-Eosin, Congo Red, and Periodic Acid Schiff. Nine samples were observed by using Hematoxylin-Eosin showed the presence of inflammation and excessive accumulation of hemosiderin pigment. The result of Congo Red staining showed two positive samples with the presence accumulation of amyloid and Periodic Acid Schiff staining showed six positive samples with the presence accumulation of carbohydrates. Three samples of six positive samples showed microorganisms were suspected belongs to systemic mycosis. The conclusions of this research showed chronic inflammation in fruit bats spleen and were suspected due to systemic infection of Blastomyces dermatitidis.
Keyword: Acerodon celebensis, fruit bats, histopathology, Pteropus hypomelanus, spleen

Judul: Spleen Histopathology of Macaca fascicularis with Klebsiella pneumoniae Infection
Abstrak: Satwa primata pada penangkaran rentan terhadap stress dan infeksi agen penyakit, termasuk Klebsiella sp. Keberadaan Klebsiella spp. pada satwa ini telah dikaitkan dengan berbagai kondisi kesehatan serius, termasuk pneumonia, meningitis, peritonitis, sistitis, dan septicemia hingga bisa menimbulkan kematian. Dalam penelitian ini, telah dikonfirmasi bahwa tiga individu Macaca fascicularis (1 jantan, 2 betina) di Pusat Studi Satwa Primata (PSSP) yang mati terinfeksi oleh Klebsiella pneumoniae. Organ limpa diambil untuk dibuat preparat histopatologi dengan pewarnaan hematoksilin eosin dan dievaluasi lesio yang terjadi secara mikroskopis. Hasil patologi anatomi dari limpa menunjukkan adanya lesion nodul putih berukuran 0.5-1.0cm yang berisi massa berwarna kuning, histopatologi menunjukkan adanya koagulasi nekrosis di pulpa putih, infiltrasi sel radang (neutrofil, limfosit, dan sel plasma) dan hemosiderosis di pulpa putih dan pulpa merah, serta perdarahan pada limpa di pulpa merah. Lesio yang ditemukan menunjukkan terjadinya splenitis pada limpa. Keberadaan lesiolesio ini akan menyebabkan disfungsi dari limpa., Primate animals are like humans in both anatomy and behavior and are therefore widely used in biomedical research. In captivity, primate animals are susceptible to stress and infection with disease agents, including Klebsiella sp. The presence of Klebsiella spp. in these animals has been associated with a variety of serious health conditions, including pneumonia, meningitis, peritonitis, cystitis, and septicemia, that can lead to death. In this study, it was confirmed that three Macaca fascicularis individuals (1 male and 2 females) at the Primate Research Center (PSSP) that died were infected by Klebsiella pneumoniae. Spleen organs were taken for histopathological preparations with hematoxylin and eosin staining, and the lesions were evaluated microscopically. Gross anatomy of the spleen showed white nodules measuring 0.5-1.0 cm in diameter, filled with a yellow, solid material. Histopathology results revealed coagulation necrosis in the white pulp, inflammatory cell infiltration (neutrophils, lymphocytes, and plasma cells) along with hemosiderosis in both red and white pulps, as well as hemorrhage in the red pulp. These lesions indicate the presence of splenitis in the spleen, leading to dysfunction in this organ.
Keyword: Klebsiella pneumoniae, Macaca fascicularis, histopathology, spleen

Judul: Analisis RSA dengan Penambahan Chinese Remainder Theorem untuk Mempercepat Proses Dekripsi.
Abstrak: RSA merupakan algoritma kunci publik yang keamanannya bertumpu pada kesulitan untuk memfaktorkan modulus n yang sangat besar, tetapi kelebihan ini mengakibatkan lambatnya waktu untuk menyelesaikan proses. Penambahan CRT pada RSA diperlukan untuk mengefisienkan kinerja RSA. Penelitian ini bertujuan untuk mempelajari kinerja RSA dari segi kecepatan dan keamanannya, serta menganalisis algoritmanya. Analisis kecepatan dilakukan dengan mengukur waktu kecepatan rata-rata enkripsi dan dekripsi RSA dan RSA-CRT. Analisis keamanan dilakukan melalui studi literatur. Dari hasil analisis algoritma, dapat ditarik kesimpulan bahwa RSA dan RSA-CRT memiliki kompleksitas yang sama untuk algoritma pembangkitan kunci dan proses enkripsi, yaitu O((lg n)3). Tetapi pada pembangkitan kunci RSA-CRT, ada bagian yang kompleksitasnya O((lg (n/2))2). Algoritma dekripsi RSA memiliki kompleksitas O((lg n)3), sedangkan RSA-CRT memiliki kompleksitas O((lg (n/2))3). Hasil ini dikuatkan oleh hasil implementasi yang memperoleh waktu dekripsi RSA-CRT yang lebih cepat dibandingkan waktu dekripsi RSA. Waktu rata-rata running time proses dekripsi RSA adalah 4211.79 ms, sedangkan pada RSA-CRT diperoleh running time rata-rata proses dekripsi 1372.44 ms. Kata kunci : RSA, RSA-CRT, Chinese Remainder Theorem.
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