Judul: Metabolomic Profile of Medicinal Plants from The Myrtaceae Family in The Belitung Regency.
Abstrak: Masyarakat Melayu di Kabupaten Belitung dominan memanfaatkan tumbuhan obat dari famili Myrtaceae, seperti Syzygium bankense, Syzygium euneuron, dan Rhodomyrtus tomentosa. Namun, informasi metabolitdari ketiga spesies tersebut masih terbatas. Profil metabolit suatu tumbuhan dapat ditentukan dengan cepat melalui studi metabolomik. Penelitian ini bertujuan menganalisis metabolit tak tertarget daun S. bankense, S. euneuron, dan R. tomentosa dari Kabupaten Belitung dan menentukan penanda kimia ketiga spesies untuk konstruksi kemosistematika menggunakan pendekatan metabolomik berbasis liquid chromatography mass spectrometry (LC-MS/MS). Daun ketiga spesies dimaserasi menggunakan etanol, lalu ekstrak dianalisis dengan LCMS/MS. Identifikasi metabolit menggunakan MZmine dan analisis multivariat menggunakan MetaboAnalyst. Sebanyak 639 metabolit teridentifikasi dari spesies S. bankense (450), S. euneuron (452), dan R. tomentosa (451). Kelas metabolit yang teridentifikasi di ketiga spesies yaitu asam lemak (29), alkaloid (36), fenolik (21), flavonoid (52), kumarin (19), terpenoid (43), karbohidrat (33), dan asam amino (46). Metabolit kandidat penanda kimia untuk S. bankense berjumlah 11, S. euneuron berjumlah 22, dan R. tomentosa berjumlah 47. Penanda kimia dengan skor variable importance on projection (VIP) tertinggi yaitu asam vanililmandelat pada S. bankense, asam madekasik pada S. euneuron, dan skropoliosida D pada R. tomentosa. Berdasarkan profil metabolit, S. bankense lebih dekat dengan S. euneuron dibandingkan R. tomentosa., The Malay Belitung community in Belitung Regency dominates the use of medicinal plants from the Mytaceae family, like Syzygium bankense, Syzygium euneuron, and Rhodomyrtus tomentosa. However, the metabolite information of leaves of the three species was unexplored. The metabolite profile of a plant can be determined rapidly through metabolomics studies.The study aims to analyze the metabolites of S. bankense, S. euneuron, and R. tomentosa leaves from the Belitung Regency and determine the markers of the species for the chemosystematic construction using a metabolomic approach based on liquid chromatography-mass spectrometry (LC-MS/MS). The leaves are macerated with ethanol, and extracts are analyzed with LC-MS/MS. Metabolite identification used MZmine and multivariate analysis was performed using MetaboAnalyst. Identified 639 metabolites of the species S. bankense (450), S. euneuron (452), and R. tomentosa (451). The metabolite classes identified in the three species are fatty acids (29), alkaloids (36), phenolic (21), flavonoids (52), coumarin (19), terpenoids (43), carbohydrates (33), and amino acids (46). The number of candidate metabolites markers are S. bankense (11), S. euneuron (22) and R. tomentosa (47), as well as the marker with the highest variable importance on projection (VIP) is vanillylmandelic acid in S. bankense, madeccasic acid in S. euneuron, and scropolioside D in R. tomentosa. Based on the metabolite profile, S. bankense is closer to S. euneuron than R. tomentosa.
Keyword: kemosistematika, LC-MS/MS, Metaboanalyst, MZmine, penanda kimia

Judul: Komposisi Vegetasi dan Potensi Tumbuhan Obat di Hutan Kerangas Kabupaten Belitung Timur Provinsi Kepulauan Bangka Belitung
Abstrak: Heath forest on East Belitung is thought to have a diversity of plant species that can be used for medications. However, the information about it has not been revealed yet. Therefore, research about composition of vegetation and potential medicinal plants in the heath forest is necessary. This research was conducted in the primay heath forest (Rimba), secondary heath forest (Bebak) and particular heath forest (Padang) at East Belitung on July to Agustus 2011. The collected data includes species of plants (local name and scientific name), species of plants used medicine and part of plants that is used for medicine. Methods that is used to collect the data is the analysis of vegetation and interview method. Analysis vegetation was done by using combination of line and compartment method. The number of lines in each forest type are 10 with each line size is 10 m × 100 m and the distance between the lines is 50 m. The research results 224 species of plants in the heath forest obtained from different habitus and growth rates. Species with the highest value of importance on seedling, bush/shrub, herbaceous, liana, rattan and pandan is the samak (Syzygium lepidocarpa) amounted to 20.2% in the primary heath forest, pulas (Guioa pleuropteris) amounted to 12.57% in the secondary heath forest and kucai padang (Fimbristylis sp.) amounted to 51.14% in the particular heath forest. Species with the highest value of important on sapling is betor belulang (Calophyllum lanigerum) amounted to 17.27% in the primary heath forest, kiras (Garcinia hombroniana) amounted to 21.50% in the secondary heath forest and sekuncong (Leptospermum flavescens) amounted to 88.46% in the particular heath forest. Species with the highest value of important on tree is seru (Schima wallichii) amounted to 53.36% in primary heath forest, seru (Schima wallichii) amounted to 103% in secondary heath forest and sekuncong (Leptospermum flavescens) amounted to 180.2% in the particular heath forest. The number of medicinal plant species are identified based on knowledge of local communities as much as 101 species. Plant family which were most widely utilized is Myrtaceae. Tree is the most common habitus of medicinal plant to be used. The part of plants which is widely used is root and the most numerous group of diseases cured with medicinal plant is diseases of body resilience system (fever). Composition of vegetation in heath forest is potential as a germ plasm reserve of medicinal plants in Indonesia. Heath forest resources conservation can support sustainability of species and benefits to community around the forest.
Keyword: 

Judul: Granular venereal disease ( GVD ) lepuh kecil pada vagina sapi teori terbentuknya dan cara pengobatannya
Abstrak: Isseponi pada tahun 1887 (dalam Williams, W.L. 1950) pertama sekali menemukan penyakit ini dengan mengamati ada nya lepuh-lepuh atau nodul dan peradangan pada mukosa vulva dan menduga merupakan penyebab terjadinya ketidak suburan dan abortus pada sapi. Sedang beberapa ahli menyatakan bahwa GVD bukan merupakan penyebab terjadinya ketidak suburan dan abortus, hanya kemungkinan adanya infeksi sekunder yang menyebabkan terjadinya sterilitas dan abortus. Sampai sekarang agen penyebab penyakit ini masih belum diketahui dengan pasti, ada yang menyatakan disebabkan oleh virus, bakteri, protozoa ataupun micoplasma. - Masa inkubasi penyakit 2 sampai 3 minggu dan dapat berjalan kronis dan ringan tanpa menimbulkan gangguan dan dapat juga berlangsung akut dan parah. Sering penyakit ini dapat sembuh sendiri tanpa diketahui pemunculannya lebih dahulu sehingga pemilik ternak tidak mengetahui hewannya pernah terserang penyakit Venereal Granular ini. Penularan paling sering terjadi melalui perkawinan alam dimana sapi-sapi jantan dapat berperan sebagai penye bar penyakit ke sapi-sapi betina lain. ...
Keyword: