Judul: Hipertrofi Kordis pada Monyet Ekor Panjang (Macaca fasicularis) Pasca Obes Induksi Diet Obesitogenik Diikuti Asupan Nikotin
Abstrak: The aim of this study was to examine the evidence of left ventricular hypertrophy of male cynomolgus macaque (Macaca fascicularis) as animal model of human obesity and atherosclerosis. The animals were fed obesitogenic diet for 12 month and treated by per-oral nicotine liquid for 3 month. The objective of this study is exploring the macroscopic aspect of fatty heart enlargement and its compensation. Almost of fifteen samples of hearts showed varies level of fatty deposition and blunted apex. Heart muscle thickening was measured on distal transversal one centimeter’s cutting using caliper with two decimal precision. Relative Wall Thickness (RWT) was measured by calculating Septal Wall Thickness (SWT) that added by Posterior Wall Thickness (PWT) and divided by Left Ventricular Internal Diameter (LVID). All of the heart mostly have concentric type of hypertrophy with elevation of RWT (1.87 ± 1.47 centimeter) compare to the normal one (0,45 centimeter). This RWT has low relations to body weight (r = 0.060) and body mass index (r =0.054). This study refilled that cynomlgous macaque can be developed as animal model of ventricular hypertrophy as a part of alternative solution of ventricular hypertrophy in conjunction with endemic obesity on urban society. This study suggested that the study of nicotine effect on ventricular hypertrophy should be conducted microscopically.
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Judul: Perubahan tingkat seluler otot jantung Monyet Ekor Panjang (Macaca fascicularis) jantan dewasa obesitas dengan intervensi nikotin
Abstrak: Obesitas telah menjadi masalah kesehatan yang serius di banyak kota besar di dunia. Masalah kesehatan ini dapat memicu terjadinya masalah-maslah kesehatan penting, seperti penyakit kardiovaskular, diabetes mellitus, stroke, kanker, sleep apnea, dan berbagai sindrom metabolik. Tujuan penelitian ini adalah untuk mendapatkan informasi perubahan tingkat seluler otot jantung pada monyet ekor panjang (Macaca fascicularis) yang obesitas secara alami maupun monyet obesitas induksi diet tinggi energi. Monyet-monyet ini terdiri dari 11 monyet jantan obesitas, yang terdiri dari monyet obesitas alami (n=2) sebagai kontrol dan tiga kelompok monyet dengan pakan obesitogenik selama 15 bulan dan nikotin cair dosis rendah (0,75mg/kg BB) per oral selama 3 bulan berikutnya (n=9). Perubahan tingkat seluler yg diamati sebagai parameter adalah degenerasi hidropik, degenerasi lemak, dan hipertrofi seluler. Hasil dari penelitian ini menunjukkan bahwa kelompok A yang diberikan pakan 10% tallow memiliki perubahan tingkat seluler dengan kaparahan paling tinggi, kelompok pakan B yang diberikan 6% tallow dan 10% kuning telur memiliki keparahan seluler tingkat menengah, dan kelompok C yang diberikan komersial monkey chow memiliki perubahan tingkat seluler dengan keparahan terendah di antara semua kelompok. Hasil ini menunjukkan bahwa perubahan tingkat seluler pada sel-sel otot jantung dipengaruhi oleh pakan dan ditentukan oleh kandungan lemak dalam pakan tersebut dan juga menunjukkan adanya pengaruh hambat dari nikotin dosis rendah terhadap perkembangan perubahan seluler jantung monyet.
Keyword: Bogor Agricultural University, Institut Pertanian Bogor, IPB, Cellular alteration, Macaca fascicularis, Nicotine, Obese

Judul: Sintesis Zeoli! X dan Nanokomposit ZeolitJTi02dari Kaolin serta Aplikasinya pada Adsorpsi Fotodegradasi Biru Metilena
Abstrak: Kaolin is rarely used as an adsorbent due to its low adsorption capacity. Therefore, kaolin was converted into zeolite and nanocomposite zeolitefri02. The products were then analyzed using x-ray diffraction and scanning electron microscope. The synthesized zeolite and nanocomposite were identified as zeolite A and zeolite X. The maximum adsorption capacity (Q) of zeolite and nanocomposite occured at the concentration of methylene blue at 300 mgIL with Q value of 17 mglg and 21 mg/g. The zeolite prepared using NaOH 2.5 I and aged at 24 hours had the highest Q value of 17 mg/g. The test results of their photodegradation properties indicate that the nanocomposite can degrade methylene blue at concentration 12.5 mg/L with percent degradation of 85.19%. The adsorption-photodegradation process of methylene blue was showed by the color of filtrate and precipitate the studied objects which were more pale than the color of control after UV irradiation at wavelength of 365 nm in 6 hours.
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