Judul: Potensi Metabolik Buah Merah Terhadap Perbaikan Hematologi dan Organ Tikus yang Diinduksi Kuinin
Abstrak: The aim of this research is to find out the influence of the red fruit extract (RFE) in the blood picture, liver and kidney of mice which induced quinine. Twenty five mice were divided into 5 groups; the groups are No (normal), the group K (quinine), the S1 (quinine and SBM 0,9 ml / kg BB/day), S2 groups (quinine and SBM 1,8 ml/ kg BB/day) and the S3 (only RFE dosage of 0,9 ml/kg BB/day). The blood sampling were done in the 0, 3rd, 7th, 10th, 14th, 17th, 20th, 23rd and 29th day. Nekropsi was done after the RFE was stopped. Liver and kidney organs were retrieved and processed into histopathology preparate with Haematoxylin-Eosin (HE) coloring. Histopathology examination was done for each group, by 20 observation of field perspective and the result were counted to get the average. Profile of blood does not change. Giving red fruit extract can increase the number of thrombocyte although statistically it was not significant (P>0,05). The damage of liver which caused by quinine, for instance hidropis degeneration, edema, and nekrosa were retarded by RFE treatment with dosage 0,9 ml/ kg BB/ day. The damage in kidney which caused by quinine (hidropis degeneration on tubuli cells, edema glomerulus, and the expansion lumen tubuli) was also retarded by the treatment. Degeneration of hidropis and nekrosa can expand in kidney with 1,8 ml/kg BB/day RFE.
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Judul: Perbandingan respon histopatologi hati dan ginjal mencit [Mus musculus] pada pemberian sari buah merah dan virgin coconut oil
Abstrak: Penelitian ini bertujuan untuk membandingkan efek pemberian sari buah merah (Pandanus conoideus) dan virgin coconut oil terhadap lesio degeneratif pada organ hati dan ginjal dengan mengamati gambaran histopatologis. Tiga puluh ekor mencit umur 2 bulan yang terdiri dari 15 ekor betina dan 15 ekor jantan masing-masing dibagi menjadi 3 kelompok perlakuan. Mencit jantan dan betina kelompok I diberi aquades sebagai kontrol dengan dosis 0,2 ml/ekor, kelompok II diberi virgin coconut oil dengan dosis 0,1 ml/ekor dan kelompok III diberi sari buah merah dengan dosis 0,12 ml/ekor. Pemberian dilakukan per oral dengan menggunakan sonde lambung, dilakukan satu kali satu hari dan diulang selama 2 bulan. Hasil pengamatan histopatologi menunjukkan bahwa persentase penurunan apoptosis, nekrosa dan degenerasi hidropis hepatosit pada pemberian virgin coconut oil lebih tinggi dibandingkan pada pemberian sari buah merah. Persentase penurunan apoptosis, degenerasi lemak dan degenerasi hialin sel epitel tubulus proksimal pada pemberian sari buah merah lebih tinggi dibandingkan pada pemberian virgin coconut oil. Namun secara uji statistika ANOVA persentase lesio pada hepatosit dan sel epitel tubulus proksimalis tidak berbeda nyata (α>0,05). Hasil pengamatan histopatologi menunjukkan bahwa pemberian sari buah merah dan virgin coconut oil tidak memberi efek toksik terhadap organ hati dan ginjal. Kata kunci: hepatosit, lesi degeneratif, sari buah merah, sel epitel tubulus proksimal, virgin coconut oil
Keyword: Degenerative lesion, Hepatocytes, Proximal tubular epithelial cells, Red fruit exctract, Virgin coconut oil

Judul: : Persamaan Tunggal sebagai Representasi Kurva Komposit
Abstrak: A mathematical method is introduced to represent a composite curve based on an extension of analytic geometry. The representation is given either with a single equation or with two equations, in the case of parametric representation. This method permits the representation of composite curves in similar manner to the conventional representation of non-composite curves. Some mathematical tools, including Heaviside unit step function and periodizer function, are used in the establishment of a single equation. In this paper, regular equations of regular and irregular polygon, as well as composite curves of two dimensions, are implemented using a computer algebraic system, Mathematica.
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