Judul: Efek Pemberian Teripang Pasir (Holothuria scabra J) terhadap Profil Imunohistokimia Antioksidan Dismutase (SOD) pada Pankreas Tikus Diabetes
Abstrak: The aim of this research is to analyse the effect of sea cucumber (Holothuria scabra J) on the profile of antioxidant enzymes copper,zinc-superoxide dismutase (Cu,Zn-SOD) in the pancreatic of diabetes mellitus rats. A total of 25 male white rats (Sprague Dawley) were used for this study. They were divided into five groups; (1) negative control (KN), (2) positive control, rats with diabetes mellitus (KP), (3) diabetic rats treated with sea cucumber protein hydrolyzate (HDL), (4) diabetic rats treated with sea cucumber protein concentrated (KST), (5) diabetic rats treated with sea cucumber protein isolate (ISL). Diabetic condition conducted by alloxan injection with doses 110 mg/kg bb. Pancreatic β cells will be damaged by alloxan, then the insulin secretion will decrease. The treatment were done for 28 days. The pancreatic tissue were obtained after treatment ends. Pancreatic tissue were fixed with Bouin solution and then processed into histological preparations. The tissue were then stained with immunohistochemical staining techniques using monoclonal antibody of Cu,Zn-SOD. The results showed that treatment of HDL, KST, and ISL sea cucumber (Holothuria scabra J) increased content antioxidant Cu,Zn-SOD in pancreatic tissue. The HDL treatment gave the best effect in increasing the antioxidant content of Cu,Zn-SOD in pancreatic tissue of diabetic rats.
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Judul: The effect of virgin coconut oil (VCO) on the profile of immunohistochemical antioxidant superoxide dismutase (SOD) in the kidney of diabetes mellitus rat.
Abstrak: The aim of this research is to evaluate the effect of virgin coconut oil (VCO) on the profile of copper zinc-superoxide dismutase (Cu,Zn-SOD) in the kidney tissue of rats. A total of 25 male white rats (Rattus novergicus), Sprague Dawley were used for this study. They were divided into 5 groups ; (1) negative control group (K-), (2) positive control/diabetic rats group which was orally treated with aquadest (K+), (3) diabetic rats treated with VCO A (VA), (4) diabetic rats treated with VCO B (VB), (5) diabetic rats treated with coconut oil (MG). Diabetic condition was achieved by alloxan injection (IP, 110 mg/kgBW). The dose of aquadest, VCO, and coconut oil was 5ml/rat/day. The treatment were done for 28 days. The kidney were obtained at the end of treatment and then processed using paraffin embedding standard methods. The tissue were then stained with Hematoxillin-Eosin and immunohistochemical technique for Cu,Zn-SOD. The kidney tissues of diabetic rats group treated with VCO showed better morphological feature and higher content of Cu,Zn-SOD compared to that of diabetic rats group treated with aquades only or coconut oil. The treatment of VCO A gave better effect on the profile of antioxidant Cu,Zn-SOD compared to VCO B. Key words : Virgin coconut oil, diabetes mellitus, superoxide dismutase (SOD), kidney, rat
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Judul: Analysis of M/G/1 Queue Model with Two Phases of Service and Bernoulli Feedback System
Abstrak: Model antrean M/G/1 dengan sistem feedback Bernoulli adalah model antrean dengan proses kedatangan mengikuti proses Poisson. Pada karya ilmiah ini dibahas sistem antrean M/G/1 dengan dua fase layanan. Setelah layanan pertama selesai, pelanggan dapat memilih untuk meninggalkan sistem dengan peluang ... dst, The M/G/1 queueing model with the Bernoulli feedback system is a queueing model with the arrival process following the Poisson process. In this manuscript M/G/1 queueing system with two phases of service is discussed. After the first service is completed, the customer can choose to leave the system with probability ... dst
Keyword: queue, Bernoulli, probability generating function, expected value