Relative reduction of body weight was significantly greater in the verum group ( -@ % ; CI = -@ to -@ ) than in the placebo group ( -@ % ; CI = -@ to +@ ; p < @ ) In addition we also observed a significant reduction of BMI ( p < @ ) in the verum group ( -@ % ; CI = -@ to -@ ) compared to placebo ( -@ % ; CI = -@ to -@ ; p < @ ) .