Current smokers ( n = @,@ ) had an increased risk of ischemic events compared with never smokers ( n = @,@ ; hazard ratio -LSB- HR -RSB- : @ -LSB- @ % confidence interval ( CI ) : @ to @ -RSB- ) and ex-smokers ( n = @,@ ; HR : @ -LSB- @ % CI : @ to @ -RSB- ) ( p < @ ) .