Decreased LV compliance , measured as reduced LV end-diastolic volume at an idealized LV end-diastolic pressure of @ mm Hg ( EDV@ ) , and RV remodeling , as indicated by increased RV wall thickness , were the @ pathophysiologic markers most predictive of worse outcomes : adjusted hazard ratio per @ SD decrease in EDV@ = @ ( @ % confidence interval -LSB- CI -RSB- , @-@ @ ; P = @ ) , and hazard ratio per @ SD increase in RV wall thickness = @ ( @ % CI , @-@ @ ; P < @ ) .