Oxidative stresses -LSB- like interleukin-@ ( IL-@ ) and tumor necrosis factor-alpha ( TNF - ) -RSB- and inflammation are the main risk factors associated with cardiovascular diseases and other complications in many organs in hemodialysis patients ; meanwhile , antioxidants like alpha lipoic acid ( ALA ) may reduce the oxidative stress markers and the levels of inflammatory cytokines , so can improve of the patient 's quality of life .