The most common grade @-@ adverse events of special interest were cardiac disorders ( @ -LSB- @ % -RSB- of @ patients in the abiraterone acetate group vs @ -LSB- @ % -RSB- of @ patients in the placebo group ) , increased alanine aminotransferase ( @ -LSB- @ % -RSB- vs four -LSB- < @ % -RSB- ) , and hypertension ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) .