We report the results of long-term follow-up of the Pacing to Avoid Cardiac Enlargement ( PACE ) trial , a prospective , double-blinded , randomized , multicentre study that confirmed the superiority of biventricular ( BiV ) pacing compared with right ventricular apical ( RVA ) pacing in prevention of LV adverse remodelling and deterioration of systolic function at @ and @ years .