Secondary outcomes include HbA@c , insulin sensitivity , lipid levels , blood pressure , serum glutathione , adiponectin , IL-@ , E-selectin , myeloperoxidase , C-reactive protein , Toll-like Receptor @ ( TLR@ ) , soluble receptor for AGE ( sRAGE ) , urinary @-isoprostanes , faecal bacterial composition and short chain fatty acid profile .