In our study cohort ( mean age @years ; mean left ventricular ejection fraction , @ % ) , impaired total LA ( LAtotal ) was associated with greater left ventricular mass index ( r = -@ , P < @ ) and worsening left ventricular diastolic function ( ratio of transmitral flow peak early diastolic velocity to peak early diastolic velocity of the mitral annulus : r = -@ , P < @ ; maximal LA volume index : r = -@ , P < @ ) .