The PREBIOUS trial ( PREventive midline laparotomy closure with a BIOabsorbable mesh ) is a multicenter randomized controlled trial in which adult patients undergoing elective or urgent open abdominal operations through a midline laparotomy incision are assigned to one of two groups based on the laparotomy closure procedure : an intervention group in which a continuous polydioxanone ( PDS ) suture is reinforced with a commercially available GORE BIO-A Tissue Reinforcement prosthesis ( W.L. Gore & Associates , Flagstaff , AZ , USA ) , or a control group with continuous PDS suture only .