Blood samples were drawn before and @ , @ , @ and @ h after induction of endotoxaemia and plasma was tested for pro-inflammatory markers ( tumor necrosis factor alpha , TNF - , interleukin-@ , IL-@ , interleukin-@ , IL-@ , and YKL-@ ) , anti-inflammatory markers ( interleukin-@ receptor antagonist , IL-@Ra , interleukin-@ , IL-@ , soluble tumor necrosis factor receptors I and II , sTNF-RI and sTNF-RII ) , marker for oxidative damage ( malondialdehyde ( MDA ) ) and antioxidative enzyme ( ascorbic acid ( AA ) and dehydroascorbic acid ( DHA ) ) .