New Cancer Strategy — House of Commons, 2015-11-19
Topic: Health
Rebecca Elizabeth Scott Harris (Conservative, Centre-right): I, too, begin by thanking the Backbench Business Committee for scheduling this very important debate and my hon. Friend the Member for Basildon and Billericay (Mr Baron) for his endeavours. A great deal has happened since we last had the chance to debate cancer, and I am pleased to be able to discuss the Independent Cancer Taskforce’s report on a cancer strategy for England, which is a major step in the right direction for all those affected by cancer As chair of the all-party group on brain tumours, I particularly welcome the focus of the report on early diagnosis. A target for 95% of patients to be diagnosed within four weeks of being referred by a GP by 2020, which has recently been implemented by the Government, is absolutely crucial for improving cancer outcomes for patients, especially those with brain tumours. Currently, 58% of brain tumours are diagnosed in accident and emergency, which unfortunately is far too late for many. That has contributed to brain tumours being the biggest cancer killer of children and adults under 40. Patients diagnosed with brain tumours have a five-year survival rate of just 19.8% compared with cancer as a whole, where 50% of patients can expect to survive for at least 10 years. Cancer survival rates doubled between 1970 and 2010, while, shockingly, brain tumour survival rates increased by a mere 7.5%. The current poor level of early diagnosis and a general lack of awareness of brain tumours contribute to the stories of far too many people. The Green family from my constituency had a son, Danny, who was a normal, happy, energetic 10-year-old who suddenly suffered a dizzy spell after playing football one afternoon. It was eventually confirmed by his local hospital that he was suffering from a brain tumour. Tragically, despite having an operation to remove the tumour, chemotherapy and radiotherapy, Danny lost his fight for survival in July 2012. He died from pneumonia Although the Greens believed that something was really seriously wrong with their child, they found that when they initially took him to hospital, doctors dismissed his symptoms as nothing more than a migraine. It was only when his condition deteriorated and he collapsed in A&E that he was sent for a CAT scan and an MRI scan. Brain tumours are relatively rare, but as Danny’s mother, Lisa, says: "They are not rare enough when it’s your relative." That is why the family would like to see patients with possible brain tumours sent for MRI scans much sooner than they currently are I very much welcome the new cancer strategy, but I have a number of concerns, including the lack of a clear, ambitious commitment to improve research. That lack of commitment impacts on the cures and treatments of the future for cancers with low survival rates, such as brain tumours. Those cancers of "unmet need" will not see the boost in survival rates that the more common cancers will, because early diagnosis and prevention alone do not affect the effectiveness of treatment to a significant extent. For example, there are no lifestyle factors that are proven to increase the likelihood of getting a brain tumour, which means that a focus on prevention will do nothing to stop the incidence of the disease, which, for whatever reason, is rising. There should be a stated priority to increase research and to find new curative and palliative treatments for rarer cancers The two excellent charities that I work with as part of the all-party group, Brain Tumour Research and the Brain Tumour Charity, have issued their own response to the new strategy. They, along with the two charities in my constituency, the Danny Green Fund and the Indee Rose Trust—the Indee Rose Trust is also tragically named after a little girl who lost her life at the age of three, five months after being diagnosed with a brain tumour—do exceptional work in raising awareness of brain tumours and of the importance of early diagnosis. They also increase the amount of funding for research and improving treatments For the strategy to be effective for people with brain tumours and to allay the concerns that I have raised, we need to focus on a few particular areas. First, we need to streamline the process of repurposing drugs. The repurposing of drugs and compounds to tackle brain tumours could open up new treatment options for patients. Repurposing refers to a process whereby a drug or a compound that has previously been used to tackle a certain illness—for example, depression—is examined and studied to see whether it can be used to tackle another illness, such as brain tumours. There is solid evidence that treatments can be developed through repurposing that are safe and effective, and that add years to the lives of patients with terminal cancers. The Government can help to streamline that process by reducing the regulation and red tape on scientists along with incentivising pharmaceutical companies to release compounds for research. The research and trials that will be sparked could result in huge strides being made in the field and in ground-breaking treatments for patients Secondly, we need a national register of all site-specific research to track all research work, grants and results. Currently, there is not a great deal of transparency in the research field. There is no clear idea of what research is being funded and what results are being achieved. That leads to confusion, duplication of work and a system that prioritises research in more common cancers rather that in diseases such as brain tumours. A national register will make research more transparent, reduce duplication and allow greater variation in the type and scope of research Thirdly, we need an innovation fund for research into rare and rarer cancers. Grant applications to existing research funding bodies require evidence of previous research—pilot work as well as published results. That results in something of a catch-22 situation. Applications must be deemed low risk in nature and as having a high likelihood of success before a grant is awarded. That means that there has to be a pre-existing bank of evidence. Novel research, particularly relating to brain tumours, suffers as a consequence of a lack of existing research. This ring-fenced fund should be set aside for areas of new research on rarer cancers and diseases. There should be a lower threshold for grants to be awarded in new projects, or in existing schemes such as the 100,000 genomes project. This stimulus will create a new wave of research that previously would not have been possible, widening our knowledge of cancer and creating the treatments we need Finally, we would like the Government to devote an absolute amount to brain tumour research. Brain tumours represent 1% of cancers diagnosed, yet 3% of cancer death. Within the innovation fund a consistent or growing absolute figure should be devoted by the Government to brain cancer research. Some 16,000 people are diagnosed with a brain tumour every year, and those affected are disproportionately children and young adults, who may have young children themselves. I hope that the Minister will commit to implementing and funding the new cancer strategy so that those 16,000 people, and indeed the tens of thousands more diagnosed with other forms of cancer, get access as quickly as possible to the treatment and the funding for research that they need to give them the best chance of survival.