araag2/NLI4PR huggingface dataset:
Clinical trial: The Role of Attention Focus Walking Training in Older Adults. (NCT04419753)

Eligibility criteria:
Inclusion Criteria:

          -  Age 65 or above;

          -  No history of cerebral vascular disease, Parkinson's disease or other neurological
             deficit;

          -  Chinese version of the Mini-Mental State Examination (MMSE-C) total score of equal or
             more than 24;

          -  Able to walk independently indoor for at least 40 meters continuously with comfortable
             pace;

          -  Older adults with moderate to high risk of falling, as indicated by the score of less
             than 24 out of 28 in the Tinetti Balance Assessment Tool.

        Exclusion Criteria:

          -  Any potential participant who cannot meet the inclusion criteria.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 65 Years old.


Patient description (medical language): A 25-year-old woman comes to the clinic with her roommate.  The roommate says that the patient has twice fallen asleep while they were talking.  The patient has regularly fallen asleep in the afternoon while reading or watching television but typically feels refreshed after a brief nap.  She also reveals that she sometimes hears a voice prior to falling asleep.  She also complains of some episodes of clumsiness that cause her to drop objects or fall. MSLT showed that the sleep latency was less than 8 min and that the patient enters rapid eye movement (REM) sleep almost immediately.

Patient description (patient's own words): I brought my roommate to the clinic because she kept falling asleep when we were having a conversation. We're both 25 and usually healthy girls. She usually takes a nap in the afternoon while reading or watching TV, but usually, she is quite energetic afterward. She told me that she sometimes hears a voice before falling asleep. How weird! And sometimes she's the clumsiest! She keeps dropping all her stuff. The doctor did a sleeping test and she found out that it takes her less than 8 min to fall asleep.

Does the patient match the trial criteria? Contradiction
Clinical trial: Lap TAP Block for Laparoscopic TEP Inguinal Hernia Repair: a Prospective, Double-blinded, Randomized, Clinical Trial (NCT02632136)

Eligibility criteria:
Inclusion Criteria:

          -  All consecutive ASA grade I-II- III patients undergoing elective unilateral
             laparoscopic total extra peritoneal (TEP) Inguinal hernia repair

          -  Age 18 - 80 yrs, including those who are having recurrent inguinal hernia repair.

        Exclusion Criteria:

          -  ASA grade IV, V

          -  Bilateral inguinal hernia repair

          -  BMI > 40 kg/m2

          -  Converted to open procedures.

          -  Conversion to Transabdominal preperitoneal (TAPP) repair

          -  Coagulopathy.

          -  Allergy to Bupivacaine.

          -  Diagnosis of "chronic pain syndrome".

          -  Known alcohol or substance abuse within the last 6 months.

          -  Daily Opioid intake.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of Crenolanib With Ramucirumab and Paclitaxel for Advanced Esophagogastric Adenocarcinoma (NCT03193918)

Eligibility criteria:
Inclusion Criteria:

          -  Pathologically confirmed adenocarcinoma of the esophagus, GEJ or stomach.

          -  Stage IV disease or locally advanced/unresectable tumors

          -  Prior progression on only 1 line of chemotherapy in the advanced/metastatic setting
             containing a fluoropyrimidine and/or platinum compound

          -  Eastern Cooperative Oncology Group (ECOG) performance status of 0-1

        Exclusion Criteria:

          -  Prior treatment with a taxane is not permitted in the dose-expansion phase. Patients
             in the dose escalation component may have received a taxane in the peri-operative
             setting, provided they developed disease recurrence >6 months after the completion of
             this therapy

          -  Known pre-existing liver disease (e.g. cirrhosis, chronic hepatitis B or C,
             nonalcoholic steatohepatitis, sclerosing cholangitis)

          -  Patients with any clinically apparent ascites or who have undergone a paracentesis
             within 7 days of enrollment

          -  Uncontrolled hypertension (systolic pressure >140 mm Hg or diastolic pressure > 90 mm
             Hg on repeated measurement) despite optimal medical management

          -  Active or clinically significant cardiac disease

          -  Patients with arterial thrombotic events, such as cerebrovascular accident or
             myocardial infarction, within 6 months of enrollment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Assessment of Cough and Wheeze With Breath Sound Documenting Device (NCT00711399)

Eligibility criteria:
Inclusion Criteria:

          -  Patient and/or parents/guardian signed informed consent

          -  Patients with cough or shortness of breath

        Exclusion Criteria:

          -  Chest tubes

          -  Skin lesions precluding attachment of sensors

          -  Respiratory distress

          -  Pregnant women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 45 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Clinical Study to Investigate the Pharmacokinetics, Efficacy, Safety and Immunogenicity of a Recombinant FVIII in Patients With Severe Hemophilia A (NCT00989196)

Eligibility criteria:
Inclusion Criteria:

          -  Severe hemophilia A (FVIII:C <= 1%)

          -  Male subjects between 12 and 65 years of age

          -  Body weight 25 kg to 110 kg

          -  Previously treated with FVIII concentrate for at least 150 EDs

        Exclusion Criteria:

          -  Other coagulation disorder than hemophilia A

          -  Present or past FVIII inhibitor activity
Male
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Heated Mittens for Patients With Hand Osteoarthritis (NCT04576403)

Eligibility criteria:
Inclusion Criteria:

          1. HOA with fulfillment of the ACR criteria:

             a. Hand pain, aching or stiffness on most days the previous 4 weeks

             And at least 3 of the following features:

               -  Hard tissue enlargement of ≥2 of the 10 selected joints*

               -  Hard tissue enlargement of ≥2 of the 10 DIP joints

               -  Fewer than 3 swollen metacarpophalangeal (MCP) joints

               -  Deformity of at least 1 of 10 selected joints* *The 10 selected joints are the
                  second and third DIP, the second and third PIP, and the first carpometacarpal
                  joints of both hands.

          2. AUSCAN Function ≥ 40 aggregated points (0-100 scale)

          3. Willing and able to participate in all study visits

          4. Able to understand and read Danish.

        Exclusion Criteria:

          1. Other diseases affecting the joints of the hand (Rheumatoid arthritis, Psoriatic
             arthritis, ect.)

          2. Widespread or generalized pain syndrome (e.g. fibromyalgia)

          3. Steroid injections in the finger joints within the last month

          4. Other condition that in the opinion of the investigator makes the participant
             unsuitable for participation.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Use of Somatropin in Turner Syndrome (NCT01518036)

Eligibility criteria:
Inclusion Criteria:

          -  Turner Syndrome

          -  Not previously treated with growth hormone or androgen

          -  Well-documented height over the previous 12 months

          -  Informed consent of parents (and child if appropriate)

        Exclusion Criteria:

          -  Growth hormone (GH) deficiency based on a GH stimulation test
Female
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 11 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Effects of Clinical Pilates and Whole Body Vibration Exercises in Postmenopausal Osteoporotic Women (NCT04259697)

Eligibility criteria:
Inclusion Criteria:

          -  Being in the postmenopausal period

          -  Having body mass index equal to or greater than 18,5 kg/m²

          -  A lack of regular exercise

          -  Having been diagnosed with osteoporosis

          -  Having the ability to walk independently

        Exclusion Criteria:

          -  Having a cardiopulmonary problem that may prevent participating in exercise programs

          -  Having kidney stones

          -  Being diagnosed with diabetes

          -  Presence of epilepsy

          -  Having cardiological problems such as arrhythmia, using a pacemaker, hypertension

          -  Having neurological disorders such as Parkinson, stroke, multiple sclerosis,
             neuropathy

          -  Having surgery in the last 6 months
Female
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Lateral Occlusion of Uterine Artery in Total Laparoscopic Hysterectomy (NCT02709460)

Eligibility criteria:
Inclusion Criteria:

          -  Women submitted to total laparoscopic hysterectomy

        Exclusion Criteria:

          -  Women <18 years

          -  Women no able to understand the study or not native in Danish

          -  Women with uterine malignancy

          -  Women with suspicion of pelvic mass

          -  Women with abnormal coagulation

          -  Women receiving glucocorticoid treatment

          -  Women receiving anticoagulant treatment or have not followed prescription in relation
             to surgery
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Acceptability and Feasibility of Medical Abortion Using Mifepristone and Buccal Misoprostol (NCT00386282)

Eligibility criteria:
Inclusion Criteria:

          -  Gestation up to 63 days

          -  General good health

          -  Willingness to provide contact information for follow-up

          -  Absence of conditions which contraindicate the use of mifepristone and misoprostol for
             pregnancy termination

        Exclusion Criteria:

          -  Ectopic pregnancy

          -  Intrauterine device (IUD) in place
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction