araag2/NLI4PR huggingface dataset:
Clinical trial: Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population (NCT01411202)

Eligibility criteria:
Inclusion Criteria:

          1. Presence of symptomatic and moderate sized (>1/3 of hemithorax) MPE

          2. Persistent malignant pleural effusion that is free-flowing

          3. Symptomatic improvement after therapeutic thoracentesis

          4. Life expectancy of at least three months (duration of study follow-up)

          5. 90% radiographic apposition of parietal and visceral pleura

          6. Residence within 30 minute radius from The Ottawa Hospital

        Exclusion Criteria:

          1. Previous lobectomy or pneumonectomy on affected side

          2. Multiple loculations

          3. Trapped or entrapped lung

          4. Untreated pleural infection

          5. Abnormal coagulation profile (INR>1.5 and / or platelet count <50 x 10*9/L)

          6. Planned intrapleural chemotherapy (however participants may receive concomitant
             systemic chemotherapy, mediastinal radiation therapy or steroids)

          7. Life expectancy less than 3 months

          8. Multiple co-morbidities limiting out-patient management of pleural effusion

          9. Tetracycline / Doxycycline allergy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Risk of Narcolepsy Associated With Administration of H1N1 Vaccine (NCT01394614)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects with symptoms of narcolepsy with onset during the period between January 1st,
             2009 and December 31, 2010.

        Exclusion Criteria:

          -  Subjects younger than 6 months of age
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.


Patient description (medical language): A 25-year-old woman comes to the clinic with her roommate.  The roommate says that the patient has twice fallen asleep while they were talking.  The patient has regularly fallen asleep in the afternoon while reading or watching television but typically feels refreshed after a brief nap.  She also reveals that she sometimes hears a voice prior to falling asleep.  She also complains of some episodes of clumsiness that cause her to drop objects or fall. MSLT showed that the sleep latency was less than 8 min and that the patient enters rapid eye movement (REM) sleep almost immediately.

Patient description (patient's own words): I brought my roommate to the clinic because she kept falling asleep when we were having a conversation. We're both 25 and usually healthy girls. She usually takes a nap in the afternoon while reading or watching TV, but usually, she is quite energetic afterward. She told me that she sometimes hears a voice before falling asleep. How weird! And sometimes she's the clumsiest! She keeps dropping all her stuff. The doctor did a sleeping test and she found out that it takes her less than 8 min to fall asleep.

Does the patient match the trial criteria? Entailment
Clinical trial: the Efficency and Safety of Stretta in GERD (NCT03574831)

Eligibility criteria:
Inclusion Criteria:

          1. Age > 18 years

          2. Small hiatus hernia (< 2-3 cm)

          3. Los Angeles Grade 'A' or 'B' Reflux Esophagitis or non erosive esophagitis

          4. LES pressure <15 mm Hg

          5. PPI dependent / refractory GERD

          6. abnormal 24h esophagus pH-impedance monitoring

        Exclusion Criteria:

          1. Age < 18 years

          2. Large hiatus hernia (> 3 cm)

          3. Los Angeles Grade 'C' or 'D' Reflux Esophagitis

          4. LES pressure > 15 mm Hg

          5. Underlying coagulation disorder

          6. Previous Esophageal or Gastric surgery

          7. Pregnant

          8. major esophagus motility disorder according to Chicago v3.0
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: Stacking Exercises Aid the Decline in FVC and Sick Time (NCT01999075)

Eligibility criteria:
Inclusion Criteria:

          -  Age 6-16 years - This age range was selected as there are accepted normative pulmonary
             function data and children 6 years of age and older are generally able to reliably
             perform pulmonary function tests. Children are followed in participating centres until
             they reach 18 years of age (allowing two years of follow-up).

          -  Clinical phenotypic features consistent with DMD and confirmed by either: (1) Muscle
             biopsy showing complete dystrophin deficiency; (2) Genetic test positive for deletion
             or duplication in the dystrophin gene resulting in an 'out-of-frame' mutation; or (3)
             Dystrophin gene sequencing showing a mutation associated with DMD.

          -  FVC ≥ 30% predicted - This range of pulmonary function was selected to exclude those
             with severe restrictive respiratory impairment, who are less likely to be able to
             reliably perform pulmonary function testing over a two year period.

          -  A caregiver willing to provide the therapy

          -  Fluency in English or French

        Exclusion Criteria:

          -  Unable to perform pulmonary function tests and/or LVR manoeuvre

          -  Presence of an endotracheal or tracheostomy tube

          -  Already using LVR and/or the Respironics in-exsufflator between and during respiratory
             infections

          -  Known susceptibility to pneumothorax or pneumomediastinum

          -  Uncontrolled asthma or other obstructive lung disease

          -  Symptomatic cardiomyopathy (ejection fraction less than 50% )
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Years old.
Subject must be at most 16 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? Entailment
Clinical trial: Inhalation of KELEA Excellerated Water in Covid-19 Infected Individuals (NCT04490824)

Eligibility criteria:
Inclusion Criteria: Individuals entering into quarantine because of a positive Covid-19
        test using either PCR or an authorized antigen assay. It is not necessary, but preferable,
        for the participant to be symptomatic for Covid-19 -

        Exclusion Criteria: Unwilling to do repeat PCR and/or antigen testing or to provide the
        results of the repeat testing or the requested clinical data

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule (NCT00579410)

Eligibility criteria:
Inclusion Criteria:

          1. Patients referred for upper endoscopy for any reason including those with acid reflux,
             dyspepsia, weight loss, Barrett's esophagus,suspected Helicobacter pylori infection.

          2. Patients able to provide written informed consent.

        Exclusion Criteria:

          1. Lack of severe comorbid conditions precluding an upper endoscopy.

          2. Patients with history of esophageal or gastric cancer.

          3. Patients status post esophageal or gastric resection.

          4. Patients with esophageal varices.

          5. Patients with severe esophageal strictures.

          6. Patients with acute upper gastrointestinal bleeding.

          7. Inability to provide informed written consent.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Effectivity of Laparoscopic Inguinal Hernia Repair (TAPP) in Daily Clinical Practice - Early and Long-term Results (NCT02561910)

Eligibility criteria:
Inclusion Criteria:

          -  All patients fit for general anesthesia and presenting an inguinal hernia.

        Exclusion Criteria:

          -  Not fit for general anesthesia, young age (>21 years), not wanting a mesh.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 21 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment