araag2/NLI4PR huggingface dataset:
Clinical trial: Short Stature Related Distress (NCT01246219)

Eligibility criteria:
Inclusion Criteria:

        1 Segment 1 :Boys at the age range of 8-13 years 2. Segment 2: Boys at the age range of
        12-17 years 3. Tanner stage 1 (segment 1 only) 4. more than 2 SD's (standard deviation)
        below the average height

        Exclusion Criteria:

          1. Mental retardation,

          2. Psychiatric illness,

          3. Lack of informed consent\assent.

          4. Health status that required chronic treatment with steroids
Male
No healthy subjects accepted to join the trial.
Subject must be at least 8 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: the Observance of Emergency Exit Treatments During the Stay of Care at the Exit of Reims Emergencies (NCT03836534)

Eligibility criteria:
Inclusion Criteria:

          -  adults

          -  consultation during the early stages of care

          -  leaving after consultation

          -  agrees to participate in the study

        Exclusion Criteria:

          -  minor patients

          -  permanently off care

          -  hospitalized patients

          -  refusal to participate in the study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 7-year-old girl is brought to the emergency department by her parents for generalized rash.  The mother reports that she was playing outside wearing a skirt and felt a sharp pain in her arm while seating on a mat, plying with her doll.  Her mother suspects that something had stung her.   The patient's blood pressure is 75/55 mm Hg and her heart rate is 122/min.  Physical examination shows erythematous, raised plaques over the trunk, extremities, and face.  Lung auscultation reveals bilateral expiratory wheezes.

Patient description (patient's own words): I just brought my seven-year-old girl to the ER because she just developed a terrible rash. My little girl was playing outside and she was wearing a lovely little skirt and all of a sudden. She felt like a really sharp pain in her arm. She was sitting on a mat playing with her doll. I think that something stung her. They took her blood pressure, and it turned out to be 75 out of 55. Her heart rate was 122. Then they did a physical examination, and it showed rashes all around her trunk, extremities, and face. Her breath test revealed some high-pitched breathing.

Does the patient match the trial criteria? Contradiction
Clinical trial: Evaluation of Patients With Endocrine-Related Conditions (NCT00005664)

Eligibility criteria:
-  INCLUSION CRITERIA:

          -  Adult patients of all ages with endocrine-related conditions will be eligible for this
             protocol.

          -  Both male and female subjects of all ethnic backgrounds are eligible.

        EXCLUSION CRITERIA:

          -  Unstable patients and patients with severe organ failure that may affect/limit the
             endocrine work-up and exhaust Clinical Center and/or NICHD resources will be excluded
             if appropriate. Decisions will be made on a case by case basis by investigators.

          -  Subjects who are unable to provide informed consent will not be accrued; however, if
             patients have previously given consent, they will continue to be seen for ongoing
             clinical care. If they require medically-indicated procedures, we will follow NIH
             policy regarding obtaining consent from next of kin if they have not indicated a
             medical decision maker.

          -  Minor subjects will not be accrued; they will be referred to NICHD protocols or other
             NIDDK protocols for evaluation of eligibility.

          -  Prisoners will not be recruited. If a subject becomes incarcerated during the study,
             s/he may continue to participate so as to not compromise medical care.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): A 33-year-old woman comes to clinic complaining of progressive fatigue, decreased appetite, and 11-lb weight loss in the past 2 months.  She uses levothyroxine because of the previously diagnosed Hashimoto disease. She has no other medical conditions and does not use tobacco, alcohol, or illicit drugs.  Physical examination shows a generalized increase in pigmentation of the skin.  Measurement of serum cortisol before and after administration of exogenous adrenocorticotropic hormone (ACTH) shows no difference in the levels. Stable glucocorticoid replacement therapy starts for her with the diagnosis for primary adrenal insufficiency (Addison disease)

Patient description (patient's own words): I went to the clinic because I was really suffering from fatigue and decreased appetite and I also lost 11 pounds over the past two months. I'm just 33 years old so that's not normal, especially for a woman. I take levothyroxine because I have been diagnosed with Hashimoto disease. I don't have any other medical condition, and I don't smoke I don't drink, and I don't do drugs. They also did my physical examination and they saw that I had an increase in pigmentation of my skin. They measured my cortisol level before and after giving me some ACTH hormone, and the results came back with no difference whatsoever. The doctor told me I have Addison disease and put me under glucocorticoid therapy.

Does the patient match the trial criteria? Entailment
Clinical trial: Electromagnetic Tracking to Measure Tremor (NCT02641366)

Eligibility criteria:
Inclusion Criteria:

          -  Adults

          -  Individuals who have undergone or are scheduled to undergo Deep Brain Stimulation
             (DBS) placement

        Exclusion Criteria:

          -  Individuals who have not had or are not scheduled for Deep Brain Stimulation (DBS)
             placement
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Contradiction
Clinical trial: Treatment of Tennis Elbow With Botulinum Toxin (NCT00119704)

Eligibility criteria:
Inclusion Criteria:

          -  Patients aged 18 years and up

          -  Pain at the lateral side of the elbow

          -  Pain at the lateral epicondyle during resisted dorsiflexion of the wrist with the
             elbow in full extension

          -  Pain for longer than 3 months

        Exclusion Criteria:

          -  Previous operations (including previous steroid injections for the disorder)

          -  Nerve entrapment

          -  Pregnancy and while breast-feeding

          -  Presence of systemic neuromuscular disorders such as myasthenia gravis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Contradiction
Clinical trial: Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome (NCT03985657)

Eligibility criteria:
Inclusion Criteria:

        People with Marfan syndrome.

          -  Age ≥ 18yrs

          -  Able and willing to provide informed consent

          -  Willing to sleep connected to research apparatus

        Exclusion Criteria:

          -  Unstable cardiovascular disease (CHF, myocardial infarction or revascularization
             procedures, and unstable arrhythmias)

          -  Uncontrolled hypertension (BP > 190/110)

          -  Underlying obstructive or other intrinsic lung disease

          -  Renal failure on dialysis

          -  Cirrhosis

          -  Pregnancy
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient description (patient's own words): I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Does the patient match the trial criteria? Entailment
Clinical trial: The Safety of Emicizumab SC Injection in Korean Patients With Hemophilia A (NCT04805801)

Eligibility criteria:
Inclusion Criteria:

          1. Patients with Hemophilia A (congenital factor VIII deficiency) who will receive
             Hemlibra SC inj. according to medical judgement of investigator (Severe for Hemophilia
             A patients without FVIII inhibitors).

          2. Signed informed consent form

        Exclusion Criteria:

          1. Subjects who are hypersensitive to Emicizumab

          2. Subjects who are hypersensitive to mouse or hamster protein

          3. Subjects with myocardial infarction or the history who are prohibited from
             administering L-Arginine containing drug

          4. Subjects who participated in other clinical trials within a month before enrollment
             (or the first administration of Hemlibra SC inj.) (Unable to participate in other
             clinical trials related to Hemophilia A treatment even after enrollment)

          5. Subjects who the investigator deems inappropriate for the study.
Male
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Entailment
Clinical trial: the Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe Covid-19 (NCT04521400)

Eligibility criteria:
Inclusion Criteria:

          -  Age ≥ 18

          -  COVID-19 Confirmed Cases (Either RT-PCR or CT Scan Confirmed)

          -  at least one of the following: radiation contactless body temperature ≥37.5, cough,
             shortness of breath, nasal congestion/ discharge, myalgia/arthralgia,
             diarrhea/vomiting, headache or fatigue on admission.

          -  Time of onset of the symptoms should be acute (Days ≤ 14)

          -  NEWS2 ≥ 1 on admission (National Early Warning Score 2)

        Exclusion Criteria:

          -  Refusal to participate expressed by patient or legally authorized representative if
             they are present

          -  Patients using drugs with potential interaction with Lopinavir/Ritonavir or
             Interferon-β 1a

          -  Pregnant or lactating women.

          -  History of alcohol or drug addiction in the past 5 years.

          -  Blood ALT/AST levels > 5 times the upper limit of normal on laboratory results.

          -  The patients who were intubated less than one hours after admission to the hospital
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Journey of Patients With Vasculitis From First Symptom to Diagnosis (NCT03410290)

Eligibility criteria:
Inclusion Criteria:

          1. Diagnosis of a systemic vasculitis: The V-PPRN includes patients with self-reported
             Behçet's disease, central nervous system vasculitis, cryoglobulinemic vasculitis,
             eosinophilic granulomatosis with polyangiitis (Churg-Strauss Syndrome, CSS), giant
             cell (temporal) arteritis (GCA), granulomatosis with polyangiitis (Wegener's, GPA),
             IgA vasculitis (Henoch-Schönlein Purpura), microscopic polyangiitis (MPA),
             polyarteritis nodosa (PAN), Takayasu's arteritis (TAK), and urticarial vasculitis.

          2. Language requirements: questionnaire will be in English only

        Exclusion Criteria:

          1. Inability to provide informed consent and complete survey in English

          2. Patients with a diagnosis of "other" type of vasculitis

          3. Patients with a "missing" diagnosis -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient description (patient's own words): I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Does the patient match the trial criteria? Entailment
Clinical trial: Ex Vivo Laboratory Assays Application for Therapy Tailoring in Patients With Severe Bleeding Disorders (NCT02324517)

Eligibility criteria:
Inclusion Criteria:

          -  Informed consent

          -  Validated coagulation disorder

        Exclusion Criteria:

          -  Not consenting to participate

          -  Multiple coagulopathies and comorbidities
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 90 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Developing a Biomarker for Monitoring Clinical Outcomes in Children With Spinal Lipoma. (NCT02722681)

Eligibility criteria:
Inclusion Criteria:

          -  patient with proven spinal lipoma

        Exclusion Criteria:

          -  complex spinal lipomas related to other developmental abnormalities
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 16 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction