araag2/NLI4PR huggingface dataset:
Clinical trial: Evaluation of Physical and Cognitive Performance After Simulated Road March Combines Physical and Cognitive Load Using a Virtual Reality Environment (NCT02644213)

Eligibility criteria:
Inclusion Criteria:

          -  aged 18-30

          -  healthy civilians volunteers

          -  with no background illnesses

          -  with history of combat unit service in the IDF.

          -  fit to perform 10 Km moderate march while carrying load.

        Exclusion Criteria:

          -  The existence or suspicion of existing cardiac or respiratory disease.

          -  Hypertension.

          -  Diabetes.

          -  Any muscles or skeleton condition.

          -  Any hormonal disease or any other chronic illness that may inhibit participation in
             the experiment.

          -  Infectious disease 3 days prior to the experiment.
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Practice and Patient Compliance on the PPI (Proton Pump Inhibitors) Treatment of Gastroesophageal Reflux in South Korea (NCT01018160)

Eligibility criteria:
Inclusion Criteria:

          -  Patients complaining about heartburn or acid regurgitation, the typical GERD symptoms,
             more than once a week

          -  After a full explanation about the observational study, patients who fully understand
             it and sign a written consent form

        Exclusion Criteria:

          -  Patients who took rabeprazole sodium within the last four weeks

          -  Patients who are hypersensitive to the active ingredient of rabeprazole sodium or
             benzimidazole

          -  Patient with other digestive tract diseases other than GERD (gastrointestinal cancer,
             liver disease, pancreatic disease, peptic ulcer, inflammatory digestive tract diseases
             [in case of ulcer, however, scars from healed ulcer may be included])

          -  Patients with other severe accompanying diseases including renal impairment,
             cerebrovascular disease, cardiovascular disease and severe respiratory disease

          -  Patients who must constantly take Proton Pump Inhibitors other than rabeprazole sodium
             during study period

          -  Pregnant or lactating women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Treating Amyotrophic Lateral Sclerosis (ALS) With R(+) Pramipexole Dihydrochloride Monohydrate at 60 mg/Day (NCT00596115)

Eligibility criteria:
Inclusion Criteria:

          -  Definite diagnosis of ALS

        Exclusion Criteria:

          -  No prior participation in R(+)PPX clinical studies
No condition on gender to be admitted to the trial.

Subject must be at least 30 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient description (patient's own words): I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Lowering Blood Pressure by Changing Lifestyle (NCT04505150)

Eligibility criteria:
Inclusion Criteria:

          -  Participants with clinic blood pressure more than or equal to 130/80 mm Hg who are not
             taking medication

          -  Participants with controlled blood pressure defined as < 130/80 using
             anti-hypertensive medication for a minimum of six weeks.

          -  Participants live in Banshgram Union only

        Exclusion Criteria:

          -  Aged > 75 years of age

          -  Pregnant women

          -  People who have advanced CVDs or are any serious condition that restricts their
             participation in the study

          -  Participants will be withdrawn from the study if they are unwilling to continue their
             participation and withdraw their consent, or any women participants who become
             pregnant during the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 30 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD) (NCT00637845)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects must have reported history of heartburn symptoms whilst on lansoprazole 30 mg
             twice daily during the 30 days prior to screening.

          -  Subjects must have a minimal cumulative heartburn score of at least 4 for a minimum of
             14 days, where zero = none, one = mild, two = moderate, three = severe.

        Exclusion Criteria:

          -  subjects history of esophageal ulcers, esophageal strictures, esophageal neoplasms,
             gastric or duodenal ulcers, or any other significant gastric or esophageal pathology
             judged to be clinically significant by the investigator.

          -  Subjects with persistent heartburn symptoms while on lansoprazole 30 mg twice daily
             for a period of > 6 months

          -  Subjects with a history of severe hepatic insufficiency (specifically, Childs-Pugh
             Class C liver disease) that may adversely affect the metabolism abd pharmacokinetics
             of esomeprazole and/or lansoprazole.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effect of Vitamin D on in Vitro Fertilization Outcome (NCT02361827)

Eligibility criteria:
Inclusion Criteria:

          1. age between 21-40 years old

          2. basal FSH hormone level less than 10 mIU/mL

          3. the first cycle of IVF treatment with standard long protocol

          4. both ovarian present and normal uterus.

        Exclusion Criteria:

          1. PGD cycles

          2. Gametes donation cycles

          3. Anyone that does not meet the inclusion criteria
Female
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Genosvid Diagnostic Test for Early Detection of COVID-19 (NCT04558372)

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed with COVID-19, non COVID-19, and suspected COVID-19 infection,
             based on the results of anamnesis, physical examination, laboratory, X-rays and rapid
             tests.

          -  Able to produce samples for RT-PCR examination.

          -  Agree to participate (sign informed consent). For children, informed consent are
             obtained from the parents. For adolescent patients, accent consent is asked.

          -  Patients who do not need oxygen therapy supplementation in the form of mask-type or
             ventilator. Patients who use oxygen supplementation with nasal cannula are still
             included as study participants.

        Exclusion Criteria:

          -  Unable to breath deeply due to difficulty breathing due to complications of COVID-19
             or other diseases

          -  The quality of the breath do not meet the standard interpretation of the instrument
             sensor curve (breath sampel is declared invalid).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Herpesvirus in Idiopathic Pulmonary Fibrosis (NCT00228670)

Eligibility criteria:
For the study on lung tissue, eligible subjects were IPF patients undergoing lung
        transplant surgery and from organ donors who died from non-pulmonary causes. For the study
        in clinic, subjects were IPF patients who had no other pulmonary disease other than IPF and
        the diagnosis of IPF was confirmed by lung biopsy or by clinical and chest CT findings. The
        control group consisted of subjects without respiratory symptoms or pulmonary diseases who
        were the household partner or spouse of an enrolled IPF subject and accompanied the IPF
        patient to outpatient clinic visits.

        Exclusion Criteria:

          -  Failure of the patient to provide informed consent.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? Contradiction
Clinical trial: Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee (NCT00980798)

Eligibility criteria:
Inclusion Criteria:

          -  Documented Osteoarthritis of the hip or knee

          -  Chronic pain for more than 3 months treated with daily analgesic for the last month

          -  Moderate to severe OA pain of the target joint, which cannot be adequately treated
             with non-steroidal anti-inflamatory drugs or paracetamol

          -  Moderate to severe pain by means of a mean weekly score of >= 5 in the Brief Pain
             Invetory item 5 'pain on average'

        Exclusion Criteria:

          -  Regular treatment with an opioid in the 4 weeks before screening visit (infrequent use
             of tramadol, codeine, tilidine, or dihydrocodeine for no more than 10 days in the 4
             weeks before the screening visit is acceptable, however, treatment must be stopped at
             screening visit)

          -  Diagnosis of major depression

          -  Treatment for epilepsy

          -  Corticosteroid injection within the last 3 months

          -  Major surgery in the 3 months before the start of the study

          -  Women who are pregnant or breast-feeding
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment