araag2/NLI4PR huggingface dataset:
Clinical trial: Evaluation of the Effectiveness of Night Orthosis in Treating Women With Symptomatic Osteoarthritis in the Interphalangeal Joint of the Dominant Hand (NCT02789852)

Eligibility criteria:
Inclusion Criteria:

          -  Women aged between 40 and 80 years.

          -  Patients diagnosed with osteoarthritis (OA) hand according to the American College of
             Rheumatology classification criteria.

          -  Pain symptom in proximal interphalangeal (PIP's) or distal interphalangeal (DIP's)
             dominant hand in II and III or fingers.

          -  Provide greater pain symptom of II and III or fingers between each other.

          -  Complains of pain symptom measured by a visual analog scale (VAS) pain between 3 to 8
             cm in the II and III or fingers of the dominant hand reported to perform joint
             movement (activity).

          -  Thumb abduction with the II and III fingers without changing the pincer movement
             pulp-pulp.

        Exclusion Criteria:

          -  Other rheumatic diseases, neurological and skeletal muscle that can affect the upper
             limb.

          -  Fibromyalgia uncontrolled.

          -  Pregnancy.

          -  Geographical inaccessibility and transport.

          -  Cognitive impairment that prevents the understanding of assessment tools.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Effectiveness of Minimally Invasive Total Knee Replacement in Improving Rehabilitation and Function (NCT00710840)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of osteoarthritis

          -  Eligible for a unilateral or bilateral primary TKA to be performed by Dr. Michael
             Dayton (University of Colorado Hospital)

          -  Minimum of 110 degrees of active knee flexion

          -  No greater than 10 degrees of anatomic knee varus, 15 degrees anatomic valgus, and 10
             degrees flexion contracture

          -  Body mass index less ≤ 40 kg/m2

        Exclusion Criteria:

          -  Any brain, circulation, or heart problems that limit function

          -  Severe osteoarthritis or other orthopedic conditions that limit function in the lower
             extremity that is not undergoing the TKA
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Effects of Stimulation Patterns of Deep Brain Stimulation (NCT02553525)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of Parkinson's Disease (PD), Essential Tremor (ET) or Multiple Sclerosis
             (MS)

          -  Scheduled to undergo Deep Brain Stimulation (DBS) electrode implant or implanted pulse
             generator (IPG) replacement surgery

          -  Neurologically stable

          -  Able to understand the study and consent form

        Exclusion Criteria:

          -  Inability to execute the motor tasks during the study

          -  Inability to tolerate withholding anti-parkinsonian and/or anti-tremor medications

          -  Clinically ineffective DBS
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: Physiological Data in the Menstrual Cycle (NCT03128983)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy, non-pregnant women aged 20-40 years (healthy volunteers)

          -  Regular cycling (28 days +/- 2)

          -  Non-hormonal contraception methods used

          -  German-speaking

          -  Written informed consent to participate in the study

        Exclusion Criteria:

          -  Any health-related issues that may affect menstrual cycle

          -  Any consumption of medication or other substances that may affect the menstrual cycle
             or any of the physiological parameters investigated

          -  Frequent travel between time zones

          -  Sleeping disorders
Female
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Determinants of COVID-19 Pneumonia (MC-19) (NCT04387799)

Eligibility criteria:
Inclusion Criteria:

          -  diagnosis of pneumonia; Covid-19 test negative; hospitalized subjects; both sexes;
             given informed consent

        Exclusion Criteria:

          -  age lower than 18 years; pregnancy; breast-feeding
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effect of Transcutaneous Electrostimulation (TENS) on Pain and Physical Function in Patients With Knee Osteoarthritis (NCT01875042)

Eligibility criteria:
Inclusion Criteria:

          -  Men and women of at least 18 years of age

          -  Clinical or radiological diagnosis of knee OA according to the criteria of the
             American College of Rheumatology

          -  Knee pain lasting for six months or longer

          -  Radiographic evidence of at least one osteophyte at the tibiofemoral joint
             (Kellgren-Lawrence grade ≥ 2) or one or more of the following signs and symptoms in
             the knee; restricted range of motion, pain in motion, crepitations, morning stiffness

          -  Written informed consent

        Exclusion Criteria

          -  Patients diagnosed with rheumatoid arthritis or other musculoskeletal diseases
             affecting lower extremities

          -  Relevant effusion in the index knee

          -  Known current or remittent cancer

          -  Carry cardiac pacemaker or defibrillator in situ

          -  Knee surgery in previous 6 months

          -  Received treatment with arthrocentesis

          -  Intra-articular injection of steroids in previous 3 months

          -  Inability to understand instructions or to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Heat Study: 2 Year Lifestyle Intervention in Overweight Women to Encourage Weight Management (NCT00128336)

Eligibility criteria:
Inclusion Criteria:

          -  Female participants

          -  Aged 25 to 70

          -  Those who have intentionally lost more than or equal to 5% of initial body weight in
             the previous 6 months will be recruited

          -  Objective evidence that volunteers were overweight or obese and have lost weight will
             be obtained from doctors records

        Exclusion Criteria:

          -  Presence of major illness including cancers

          -  Established cardiovascular disease or stroke

          -  Diabetes

          -  Gestational diabetes

          -  Renal disease

          -  Malabsorption disorders

          -  Thyroid disorders

          -  Major psychiatric disorders

          -  Taking weight loss medication or medications known to cause weight gain

          -  Planning a pregnancy in the next 2 years

          -  Those who do not intend to be in the area for the next 2 years
Female
Accepts Healthy Volunteers
Subject must be at least 25 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: The CEDiD Study (COVID-19 Early Diagnosis in Doctors and Healthcare Workers) (NCT04363489)

Eligibility criteria:
Inclusion Criteria

          -  Healthy healthcare professionals of any age

        Exclusion Criteria

          -  Previous PCR/Antibody positive test for COVID-19

          -  Not working in high-risk COVID-19 area (ICU, A&E, COVID positive wards)

          -  Involved in COVID-19 Vaccine Trial
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Linkage Study in Familial Pulmonary Fibrosis (NCT00016627)

Eligibility criteria:
No eligibility criteria
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? Entailment
Clinical trial: Hymovis™ Versus Placebo in Knee Osteoarthritis (NCT01372475)

Eligibility criteria:
Inclusion Criteria:

          1. Male or female ambulant outpatients ≥ 40 years of age with an active lifestyle:

          2. Has a medical history of OA symptoms confirmed at least 3 months prior to the
             screening visit with radiographic evidence of OA, Kellgren-Lawrence grade 2-3

          3. Discontinuation of any analgesic/NSAID therapy prior to baseline with no intent to
             resume during study

        Exclusion Criteria:

          1. Clinically significant apparent large effusion of the target knee;

          2. Clinically significant valgus/varus deformities, ligamentous laxity or meniscal
             instability as assessed by the Investigator;

          3. Any musculoskeletal condition affecting the target knee that would impair assessment
             of the effectiveness in the target knee such as Paget's disease

          4. Medical history of anaphylactic reactions

          5. History of septic arthritis in any joint

          6. Females who are pregnant or breast-feeding
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: GRIB Forsoeget-2004 (NCT00554645)

Eligibility criteria:
Inclusion Criteria:

          -  Weight compared to hight over 135% of the Danish norms (www.peadiatri.dk)

        Exclusion Criteria:

          -  None of the parents wants to participate

          -  Diagnosed somatic course of overweight

          -  Parents or children do not speak danish

          -  Sever physical handicap

          -  Psychiatric illness or mental retardation in children or parents

          -  Severe child abuse

          -  Siblings participation in the trail.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 10 Years old.
Subject must be at most 15 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction