araag2/NLI4PR huggingface dataset:
Clinical trial: Kefir on Bone Mineral Density and Bone Metabolism in Osteoporotic Patients (NCT02361372)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of osteoporosis patients

        Exclusion Criteria:

          -  Any previous use of parathyroid hormone or sodium fluoride, use of anabolic steroids
             or growth hormone within 6 months before trial entry or oral or intravenous systemic
             corticosteroids within 12 months, and any previous use of strontium.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 55 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: WheezoMeter® Correlation Study (NCT01556958)

Eligibility criteria:
Inclusion Criteria:

          -  Patients <= 12 years of age who have wheezing at the time of study as confirmed by the
             physicians' auscultation.

        Control:

          -  Patients <= 12 years of age without history of asthma or other pulmonary conditions,
             and who are without wheezing on physical exam.

        Exclusion Criteria:

          -  Medical problems that would contraindicate Wz% measurement.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers

Subject must be at most 12 Years

Patient description (medical language): A 7-year-old girl is brought to the emergency department by her parents for generalized rash.  The mother reports that she was playing outside wearing a skirt and felt a sharp pain in her arm while seating on a mat, plying with her doll.  Her mother suspects that something had stung her.   The patient's blood pressure is 75/55 mm Hg and her heart rate is 122/min.  Physical examination shows erythematous, raised plaques over the trunk, extremities, and face.  Lung auscultation reveals bilateral expiratory wheezes.

Patient description (patient's own words): I just brought my seven-year-old girl to the ER because she just developed a terrible rash. My little girl was playing outside and she was wearing a lovely little skirt and all of a sudden. She felt like a really sharp pain in her arm. She was sitting on a mat playing with her doll. I think that something stung her. They took her blood pressure, and it turned out to be 75 out of 55. Her heart rate was 122. Then they did a physical examination, and it showed rashes all around her trunk, extremities, and face. Her breath test revealed some high-pitched breathing.

Does the patient match the trial criteria? Entailment
Clinical trial: Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia (NCT00061789)

Eligibility criteria:
INCLUSION CRITERIA:

        Controls-Group 1:

        Healthy Diagnosis;

        21-80 years;

        No Cigarette Smoking;

        Plasma Cotinine less than 3 ng/mL;

        No olanzapine or risperidone

        Smoker Patients-Group 2:

        Diagnosis of Schizophrenia;

        21-50 years;

        Cigarette Smoking greater than 20 per day and greater than 5 years;

        Plasma Cotinine greater than 100 ng/mL;

        Olanzapine or risperidone greater than 6 mo. and same dose for 2 weeks

        Non-Smoker Patients-Group 3:

        Diagnosis of Schizophrenia;

        21-50 years;

        No Cigarette Smoking;

        Plasma Cotinine less than 3 ng/mL;

        Olanzapine or risperidone greater than 6 mo. and same dose for 2 weeks

        Smoker Controls-Group 4:

        Healthy Diagnosis;

        21-50 years;

        Cigarette Smoking greater than 20 per day and greater than 5 years;

        Plasma Cotinine greater than 100 ng/mL;

        No olanzapine or risperidone

        Non-Smoker Controls-Group 5:

        Healthy Diagnosis;

        21-50 years;

        No Cigarette Smoking;

        Plasma Cotinine less than 3 ng/mL;

        No olanzapine or risperidone
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Efficacy of Fenugreek Supplementation on Men's Health (NCT03528538)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy men between the ages of 21- 45 that were recreationally active.

        Exclusion Criteria:

          -  Above 30% body composition, not in the age range, history of asthma, diabetes,
             hypoglycemia, or took any hormonal supplements such as testosterone or anabolic
             steroids.
Male
Accepts Healthy Volunteers
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb (NCT01542515)

Eligibility criteria:
Inclusion Criteria:

          -  Stage I - III osteoarthritis / traumatic arthritis of the thumb.

        Exclusion Criteria:

          -  Exclusion criteria were diabetes mellitus, kidney insufficiency, OA in the STT joint,
             or malignancy within the past 10 years.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 95 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Lactobacillus Reuteri in Children With Constipation (NCT01388712)

Eligibility criteria:
Inclusion Criteria:

          -  Children 3-7 years old

          -  Occurrence less than three bowel movement per week

          -  Medical history from at least two months]

          -  Ineffective laxative treatment at least two months

          -  The parents approval for child participation in the study and for the treatment

        Exclusion Criteria:

          -  Well-known, organic cause of constipation (i.e. hypothyroidism, Hirschprung disease,
             cystis fibrosis)

          -  Anatomic defects of the alimentary canal

          -  The surgery of the alimentary canal in the past

          -  Treatment of antibiotics/probiotics during last two weeks before start of the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.
Subject must be at most 7 Years

Patient description (medical language): A 7-month-old boy is brought to emergency by his parents due to irritability and inability to defecate for the past 3 days.  The patient has had constipation and discomfort with bowel movements since birth.  His symptoms worsened after eating semi-solid foods.  Vital signs are normal.  Abdominal examination shows distension and tenderness to palpation with presence of bowel sounds.  Xray with barium shows a narrow rectum and rectosigmoid area.  The rest of the colon proximal to this segment is dilated. Digital rectal exam revealed burst of feces out of the anus. The biopsy showed absence of submucosal ganglia in the last segment of the large intestine.

Patient description (patient's own words): My baby boy just turned 7 months old but my wife and I cannot get a hold of him! He has not been able to poop for 3 days! My poor little thing has been having constipation and bowel problems since birth. But since he ate some semi-solid food it has just been worse! The doctor said his vitals are normal but his belly is tense and tender with his bowels making noise. They did an X-ray and found out that he had a narrow rectum. His colon is dilated. They also performed a touch rectal exam and he could finally poop! The biopsy revealed that there is no submucosal ganglia in his large intestine.

Does the patient match the trial criteria? Contradiction
Clinical trial: Sodium Pyruvate Nasal Spray Treatment of COVID-19 and Influenza Infections (NCT04824365)

Eligibility criteria:
Inclusion Criteria:

          1. Individuals with a confirmed COVID-19/influenza viral infection, as determined by a
             qualified laboratory test. A nasal swab or saliva test analyzed by qPCR for COVID19 or
             rapid flu test from nasal swab for influenza.

          2. Individuals who agree to abstain from sexual intercourse, or agree to use condoms or
             vaginal diaphragms or other devices designed to prevent contraception, during the
             entire course of the study

        Exclusion Criteria

          1. Viral infections other than COVID-19 or influenza.

          2. Clinically significant cardiac disease including uncontrolled congestive heart failure
             and unstable angina

          3. Pregnancy

          4. Females of child bearing potential age not on adequate contraception or lactating

          5. Subjects receiving systemic corticosteroid treatment within one month of Screening
             Visit

          6. Subjects Less than 18 years of age

          7. Hospitalization within last 6 months due to acute exacerbation of airway disease

          8. Subjects with a clinically significant abnormal chest x-ray within past 12 months

          9. Medication changes within one month of study entry

         10. Subjects who have participated in another investigation drug treatment study within
             the previous month.

         11. Subjects with a current history of alcohol or recreational drug abuse.

         12. Subjects who have taken dietary supplements containing pyruvate within 24 hours prior
             to the screening visit.

        Inclusion of Women and Minorities Every attempt will be made to include all genders, and
        minorities that present with an active COVID-19 or flu infection that are not exempted due
        to exclusion criteria.

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparison of Osteoporosis Disease Management Strategies (0000-039) (NCT00145080)

Eligibility criteria:
Inclusion Criteria:

          -  Members of the Harvard Pilgrim Health Plan

        Exclusion Criteria:

          -  Individuals who are not members of the Harvard Pilgrim Health Plan
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 64 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With Idiopathic Pulmonary Fibrosis (IPF) (NCT01874223)

Eligibility criteria:
Inclusion Criteria:

          -  Completion of informed consent.

          -  Adults over the age of 18.

          -  Diagnosis of IPF per ATS guidelines.

          -  Clinically stable at the time of enrollment defined as no antibiotics within the past
             month, with the exception of those patients currently listed for Lung Transplantation.

          -  No changes in immunosuppressive regimens (if applicable) over past month.

        Exclusion Criteria:

          -  Inability to understand or complete paper and pencil questionnaires.

          -  Patient not planning to return to Stanford for clinic visits.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? Entailment
Clinical trial: Minimally Invasive Sweet Esophagectomy for Patients With Siewert Type II Adenocarcinoma of the Esophagogastric Junction (NCT02741778)

Eligibility criteria:
Can tolerate the cT1~3N0~1M0 phase II type II esophageal gastric junction adenocarcinoma
        patients with the corresponding operation, the past or present without radiotherapy,
        chemotherapy, nearly 5 years without any other malignant tumor history. According to the
        research design, random access to minimally invasive surgery group or traditional open
        surgery group. The follow-up procedure, if the cause of the disease or the treatment of the
        disease has been confirmed, such as the need for adjuvant chemotherapy, should be treated
        accordingly, according to the statistics appear to be accompanied by the interference to
        explain and deal with.

        Inclusion Criteria:

        A. under 70 years of age (taking into account the follow-up period); B. was performed in
        patients with cT1~3N0~1M0 type II type cTNM, C., F., D., e., and 5 years.

        Exclusion Criteria:

        I A., type III esophageal gastric junction adenocarcinoma; B. major organ function can not
        tolerate surgery; C. advanced patients.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment