araag2/NLI4PR huggingface dataset:
Clinical trial: Mesh Fixation and Closure of Peritoneum Following Laparoscopic Hernia Repair Using N-butyl Cyanoacrylate (NCT02457728)

Eligibility criteria:
Inclusion Criteria:

          -  Inguinal hernia,

          -  femoral hernia

        Exclusion Criteria:

          -  pregnancy,

          -  not able to understand patient information
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Minimally Invasive Benign Hysterectomy (NCT01865929)

Eligibility criteria:
Inclusion Criteria:

          -  indication for hysterectomy for benign disease or prophylactic surgery due to
             hereditary cancer

          -  size of uterus and vagina allows for retrieval by the vaginal route

          -  maximum uterine size equivalent to 16 weeks of pregnancy

          -  informed consent

        Exclusion Criteria:

          -  malignant disease

          -  known extensive intra-abdominal adhesions

          -  anaesthesiological contraindications to laparoscopic surgery

          -  women with pacemaker or other implants where electrosurgery is to be avoided

          -  immunoincompetent women

          -  simultaneous need for prolapse surgery

          -  women with known defects of the hemostasis

          -  allergies towards metronidazole and doxycycline

          -  inability to understand patient information
Female
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Vitamin E and Male Infertility (NCT00178516)

Eligibility criteria:
Inclusion Criteria:

          -  infertile men with previously abnormal semen analyses.

          -  Control group: fertile adult males

        Exclusion Criteria:

          -  Proxceed use within 3 months of the start of study.

          -  Vitamin E supplements with > 45 IU daily
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of FYU-981 in Hyperuricemia With or Without Gout (NCT03006445)

Eligibility criteria:
Inclusion Criteria:

          -  Hyperuricemic or gout patients

          -  Serum urate level:

        >= 7.0mg/dL in patients with history of gout, or >= 8.0mg/dL in patients with hypertension,
        diabetes or metabolic syndrome, or >= 9.0mg/dL

        Exclusion Criteria:

          -  Gouty arthritis within two weeks before start of study treatment

          -  Secondary hyperuricemia

          -  HbA1c: >= 8.4%

          -  Uric acid-overproduction type in the classification of hyperuricemia

          -  History of, clinically significant cardiac, hematologic and hepatic disease

          -  Kidney calculi or clinically significant urinary calculi

          -  eGFR: < 30mL/min/1.73m^2

          -  Systolic blood pressure: >= 180 mmHg

          -  Diastolic blood pressure: >= 110 mmHg
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.


Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Clinical Evaluation of AI-aided Auscultation With Automatic Classification of Respiratory System Sounds (NCT04208360)

Eligibility criteria:
Inclusion Criteria:

          -  Children between 3 months and 18 years old (inclusive) admitted and hospitalized in
             the pulmonary disease ward (PL and EU).

          -  Children between 3 months and 18 years old (inclusive) admitted and hospitalized in
             the pulmonary disease ward or treated in an outpatient clinic (US).

          -  Informed consent of parents or caregivers, according to local regulations.

        Exclusion Criteria:

          -  Skin/soft tissue disease or local infection at the site of pulmonary auscultation or
             any other contraindication for the pulmonary auscultation.

          -  Any concurrent disease or condition that, in the opinion of the investigator, would
             make the patient unsuitable for participation in the project.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Months old.
Subject must be at most 18 Years

Patient description (medical language): A 7-year-old girl is brought to the emergency department by her parents for generalized rash.  The mother reports that she was playing outside wearing a skirt and felt a sharp pain in her arm while seating on a mat, plying with her doll.  Her mother suspects that something had stung her.   The patient's blood pressure is 75/55 mm Hg and her heart rate is 122/min.  Physical examination shows erythematous, raised plaques over the trunk, extremities, and face.  Lung auscultation reveals bilateral expiratory wheezes.

Patient description (patient's own words): I just brought my seven-year-old girl to the ER because she just developed a terrible rash. My little girl was playing outside and she was wearing a lovely little skirt and all of a sudden. She felt like a really sharp pain in her arm. She was sitting on a mat playing with her doll. I think that something stung her. They took her blood pressure, and it turned out to be 75 out of 55. Her heart rate was 122. Then they did a physical examination, and it showed rashes all around her trunk, extremities, and face. Her breath test revealed some high-pitched breathing.

Does the patient match the trial criteria? Contradiction
Clinical trial: Women Initiating New Goals of Safety (NCT01788579)

Eligibility criteria:
Inclusion Criteria:

          -  She is 18 or older

          -  She is currently court supervision at Bronx Community Solutions or a drug treatment
             court or she is currently on probation.

          -  She reports using any illicit drug or drinking 4 or more alcoholic drinks in a 6-hour
             period in the past 90 days or she has been in alcohol or drug treatment in the past 6
             months OR if she report attending any drug or alcohol treatment in the past 6 months.

          -  She reports having had an ongoing intimate, dating or sexual relationship with a male
             or female partner that lasted 3 or more months in the past year.

          -  She lives within a 90-minute commute of 125th and Broadway

        Exclusion Criteria:

          -  Ability to speak and understand English is not sufficient to participate in
             assessments or intervention sessions.

          -  Inability to complete informed consent process due to a psychiatric or cognitive
             impairment.

          -  The participant is unwilling or unable to commit to completing all the activities in
             the study.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: Diagnostic of Transient Lower Esophageal Sphincter Relaxation With Combined Impedance and High Resolution Manometry in Patients With GERD (NCT01844440)

Eligibility criteria:
Inclusion Criteria:

          -  Patients 18 to 75 years old

          -  GERD documented by :

               -  Typical reflux symptoms (heartburn, regurgitations) completely responsive to PPI
                  therapy

               -  And/or erosive esophagitis or Barrett's esophagus at endoscopy

               -  And/or positive pH 24h monitoring (acid exposure time > 5% or positive symptom
                  association indices)

          -  Possibility of easily positioned transnasal catheter

          -  Patients covered by social security

          -  Subjects must provide written, free and informed consent

        Exclusion Criteria:

          -  Pregnant or lactating women

          -  History of digestive or thoracic surgery (except appendicectomy)

          -  Patients unable to stop PPI therapy for 7 days

          -  Subjects unable to provide written consent, including adult under guardianship and
             emergency situation

          -  Simultaneous participation in another study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: An Ascending Multiple Dose Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women With Low Bone Mineral Density (NCT01101048)

Eligibility criteria:
Inclusion Criteria:

          -  Low bone mineral density as determined at the time of screening [as defined by bone
             mineral density (BMD) T-scores of the lumbar spine (L1-L4), or total evaluable
             vertebrae (if fewer than L1-L4); or femoral neck between -1.0 and -2.5, exclusive]

          -  25-hydroxyvitamin D ≥ 20 ng/mL

          -  Willing and able to take ≥ 1,000 mg elemental calcium and ≥ 800 IU (but ≤ 1,000 IU)
             vitamin D daily upon enrollment

        Exclusion Criteria:

          -  Osteoporosis, as defined by BMD T-scores of the lumbar spine (L1-L4) or total
             evaluable vertebrae (if fewer than L1-L4); or femoral neck ≤ 2.5

          -  History of vertebral fracture, or fragility fracture (a fracture resulting from no or
             minor trauma; ie, fall from standing height or less) of the wrist, humerus, hip, or
             pelvis after age 50

          -  Diagnosed with any condition that will affect bone metabolism

          -  Diagnosis of clotting factor deficiency or history of bleeding or coagulation disorder

          -  History of spinal stenosis

          -  History of facial nerve paralysis

        Exclusion Criteria for Cohort 7 Sub-study (Transition to Alendronate):

          -  Contraindicated or intolerant of alendronate therapy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Pregnancies of Uncertain Location or Viability Research (NCT02700789)

Eligibility criteria:
Inclusion Criteria:

          -  Positive urinary pregnancy test performed 18 days after oocyte retrieval in a fresh
             treatment cycle or 13-16 days after embryo transfer in a frozen embryo replacement
             cycle depending on the stage of embryo development at the time of transfer

        Exclusion Criteria:

          -  Negative urinary pregnancy test performed 18 days after oocyte retrieval in a fresh
             treatment cycle or 13-16 days after embryo transfer in a frozen embryo replacement
             cycle depending on the stage of embryo development at the time of transfer

          -  No evidence of an intrauterine fluid collection during the index test

          -  Evidence of a yolk sac and/or fetal pole during the index test

          -  Final diagnosis not known
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Entailment