Clinical trial: Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19 (NCT04391946)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of chronic lymphocytic leukemia / lymphocytic lymphoma or Waldenstrom
             disease according to the criteria of the WHO 2016 with a proven or probable infection
             by COVID-19 according to the following criteria:

          -  Proven infection: PCR positive regardless of the radio-clinical picture (Other tests
             made available later and having good diagnostic performance will be accepted)

          -  Probable infection: the diagnosis of probable infection is retained in case of
             negative PCR or not made if presence of at least 2 major criteria or of a major
             criterion associated with at least 2 minor criteria among the following, in the
             absence other documented cause.

          -  Major criteria:

               -  Fever

               -  Loss of smell / taste

               -  At least one respiratory sign among cough, dyspnea, chest pain

               -  Radiological signs suggestive of the scanner (areas or diffuse appearance of
                  frosted glass, condensations including pseudonodular condensations, association
                  of frosted glass and condensation within the same lesion, nodules and
                  micronodules, thickening of the interlobular septa) or on an X-ray of the thorax
                  ( interstitial, alveolo-interstitial or alveolar syndrome, unilateral or
                  bilateral)

               -  Notion of storytelling with a person whose SARS-CoV-2 infection has been formally
                  documented

          -  Minor criteria

               -  Aches

               -  Sore throat

               -  Rhinorrhea

               -  Headache

               -  Diarrhea

               -  Abdominal pain

               -  Frank asthenia

               -  Conjunctivitis

        Exclusion Criteria:

          -  Patient opposition
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction