araag2/NLI4PR huggingface dataset:
Clinical trial: Evaluation of the Prevalence of Functional Digestive Disorders During Primary Sjögren Gougerot Syndrome (NCT03157011)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with SGSp according to revised American-European criteria

          -  Patients 18 years of age or older

          -  Patients affiliated to the French social security care system.

        Exclusion Criteria:

          -  Patients under measure of maintenance of justice.

          -  Patients unable to understand or to participate to the study.

          -  Child and major patients making the object of a measure of lawful protection.

          -  Patients deprived of freedom.

          -  Concomitant interventional clinical trial
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? Entailment
Clinical trial: Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle (NCT02576860)

Eligibility criteria:
Inclusion Criteria:

          1. Healthy, male and non-pregnant female subjects, 18 years of age or older.

          2. A diagnosis of papulopustular rosacea with ≥30 inflammatory facial lesions at
             Baseline. Subjects must have no more than 2 nodular lesions, at Baseline.

          3. Subjects with the presence of telangiectasia at Baseline.

          4. Subjects with an erythema score of at least 2 on the Investigator Assessment of
             Erythema scale at Baseline.

          5. Subjects with severe rosacea on the Investigators Global Assessment scale at Baseline.

        Exclusion Criteria:

          1. Subjects with steroid rosacea or subtype 3 (phymatous rosacea).

          2. Subjects with nodular rosacea.

          3. Standard exclusion criteria.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? Entailment
Clinical trial: Laparoscopic vs Open Hernia Mesh Repair for Inguinal Hernia (NCT00311935)

Eligibility criteria:
Inclusion Criteria:

          -  Male <60yrs with primary inguinal hernia

        Exclusion Criteria:

          -  Recurrent hernia

          -  Bilateral hernia

          -  Non-reducible/obstructed hernia

          -  Previous lower abdominal surgery/radiotherapy
Male
No healthy subjects accepted to join the trial.
Subject must be at least 15 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor (NCT01734122)

Eligibility criteria:
Inclusion Criteria:

          -  Must be certified by a neurologist as having essential tremor or Parkinsonian tremor
             that is insufficiently controlled by medication alone.

          -  Preference to receive radiation treatment for tremor treatment, rather than surgical
             DBS implantation or surgical thalamotomy

          -  At least 18 years old

        Exclusion Criteria:

          -  Contraindications to cranial radiation (such as prior radiation to the thalamus)

          -  Inability to have a MRI of the brain

          -  Prior surgical thalamotomy treatment (but contralateral deep brain stimulator [DBS] is
             permitted)

          -  Estimated life expectancy less than 1 year
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: Evaluating Face-Recognition Technology in Syndrome Diagnosis (NCT04709965)

Eligibility criteria:
Inclusion Criteria:

        - Patients attending routine genetic clinic/paediatric clinic appointments for diagnosis of
        a multiple anomaly syndrome where distinctive facial features form part of their presenting
        pattern.

        OR:

        - Biochemically or genetically confirmed diagnosis of inborn disorder of metabolism where
        no well described dysmorphic facial features are known to be associated with disorder

        Exclusion Criteria:

          -  Patients under 8 months of age where face-recognition technology has not been shown to
             be effective.

          -  Patients who decline clinical photography as part of standard care.

          -  Patients who do not wish to consent to participation in the study even though they
             consent to photos being taken for standard care.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 8 Months old.


Patient description (medical language): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient description (patient's own words): I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy of Antituberculous Therapy in Management of Sarcoidosis (NCT01245036)

Eligibility criteria:
Inclusion Criteria:

        newly diagnosed sarcoidosis defined by presence of all of the following criteria:

          1. Presence with clinical features of pulmonary (dyspnea, dry cough, chest pain, fever,
             fatigue or crackles) or extra pulmonary organ (lymph nodes, liver, spleen, skin, eyes,
             heart, etc.) involvement and consistent radiological involvement and

          2. Compact non-caseating granulomas on trans-bronchial biopsy which are tissue AFB
             smear-negative

        Exclusion Criteria:

        Patients who have received glucocorticoid treatment before initial evaluation by us, or
        with presence of concomitant other cardio pulmonary disease will be excluded.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 15 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? Entailment
Clinical trial: Are Serum Levels of Vascular Endothelial Growth Factor a Marker for the Early Diagnosis of Ectopic Pregnancy? (NCT01261026)

Eligibility criteria:
Inclusion Criteria:The inclusion criterion was the presence at transvaginal ultrasound of
        an extraovarian adnexal mass in women with a suspected ectopic pregnancy (amenorrhea,
        bleeding and pain) with positive test for beta-hCG.

        -

        Exclusion Criteria:The exclusion criterion was non-tubal ectopic pregnancy (cervical,
        cesarean scar, ovarian, and abdominal).

        -
Female

Subject must be at least 15 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Entailment
Clinical trial: The Detection of Glaucoma Using Pupillography (NCT01462526)

Eligibility criteria:
Inclusion Criteria:

          -  Age 40 years or older at enrollment

          -  Presenting visual acuity better than 20/100 in both eyes

          -  Spherical equivalent refractive error within the range of 4.0 and -6.0 diopters in
             both eyes

        Exclusion Criteria:

          -  Ocular surgery in either eye within 3 months
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.


Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Entailment
Clinical trial: Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol (NCT03132142)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy

          -  Speaks and understands English or Danish

          -  18-60 years

        Exclusion Criteria:

          -  Pregnancy or lactation

          -  Drug addiction

          -  Previous or current dermatological, neurological, musculoskeletal or mental illnesses

          -  Lack of ability to cooperate

          -  Current use of medications that may affect the trial
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: Study Comparing Outcomes Between Conventional IVF and a "Freeze-all"-Strategy in Assisted Reproductive Technology (NCT02746562)

Eligibility criteria:
Inclusion Criteria:

          -  AMH (Anti-Müllerian hormone) > 6.28 pmol/L (Roche Elecsys assay)

          -  Female age 18 years to less than 40 years

          -  1, 2 or 3 IVF/ICSI cycle with oocyte aspiration

          -  Regular menstrual cycle between 24 and 35 days

          -  BMI between 18 and 35

          -  Two ovaries

          -  Can and will sign informed consent

        Exclusion Criteria:

          -  Women who do not fulfil the inclusion criteria

          -  Endometriosis stage III to IV

          -  Ovarian cysts with diameter > 30 mm at day of start of stimulation

          -  Submucosal fibroids

          -  Women with severe co-morbidity (IDDM, NIDDM, gastrointestinal, cardiovascular,
             pulmonary, liver or kidney disease)

          -  Dysregulation of thyroid disease

          -  Not danish or English speaking women

          -  Contraindications or allergies to use of Gonadotrophins or GnRH antagonists

          -  TESA (testicular sperm aspiration)

          -  OD (oocyte donation)

          -  Previous inclusion in the study
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 39 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Postoperative Pain After Extraperitoneal Endoscopic Technique (TEP) vs. Lichtenstein Hernioplasty in Inguinal Hernia Repair (NCT03566433)

Eligibility criteria:
Inclusion Criteria:

        Clinical diagnosis of symptomatic inguinal hernia Age 18-80

        Exclusion Criteria:

        Large scrotal hernia Bilateral hernia Symptom-free hernia Inguinal pain without clinical
        evidence of hernia Asa class≥3
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment