araag2/NLI4PR huggingface dataset:
Clinical trial: A Comparison of Accelerometers for Measuring Daily Activity in Sarcoid (NCT02626897)

Eligibility criteria:
Inclusion Criteria:

          1. Male or Female aged over 18

          2. Diagnosed with sarcoidosis by either; biopsy confirming non-caseating granulomas
             consistent with sarcoidosis, or multi-disciplinary interstitial lung disease meeting
             diagnosis of sarcoidosis.

          3. Ambulatory patient (not wheelchair or bed-bound)

          4. Able to provide written informed consent

        Exclusion Criteria:

        1. Unable to provide informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? Entailment
Clinical trial: Oxandrolone Compared With a Placebo on Growth Rate in Girls With Growth Hormone-Treated Turner's Syndrome (NCT00004275)

Eligibility criteria:
PROTOCOL ENTRY CRITERIA:

        Turner's syndrome-compatible karyotype No Y material in peripheral karyotype Bone age no
        greater than 11 years --Prior/Concurrent Therapy-- No more than 12 months of prior
        estrogen, androgen, or growth hormone
Female
No healthy subjects accepted to join the trial.
Subject must be at least 10 Years old.
Subject must be at most 14 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Positively Quit Trial for Smoking Cessation (NCT04449458)

Eligibility criteria:
Inclusion Criteria:

          -  greater than or equal to age 18 (as NRT is not FDA approved for adolescents)

          -  self-report smoking cigarettes

          -  positive cotinine test

          -  motivated to quit

          -  own a smart phone, laptop, desktop, or tablet computer

          -  able to join group from a private space with Internet access

          -  demonstrate the ability to connect to the HIPAA-compliant videoconferencing system,
             Zoom, over the internet h) speak English i) can provide Florida residency
             (state-issued identification or mail with person's name and Florida address) j) living
             with certain health conditions

        Exclusion Criteria:

          -  pregnant, breastfeeding, or have other contraindications to NRT

          -  receiving other tobacco treatment, or

          -  inability to communicate coherently in English during the video-conferencing test or
             other pre-enrollment interactions
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: A Comparison of Two Self-management Programmes for Patients With Back Pain (NCT03791164)

Eligibility criteria:
Inclusion Criteria:

          -  : patients with back pain who have been referred to the North of England regional back
             pain service who consent to take part in the study

        Exclusion Criteria:

          -  Exclusion criteria are patients with red flag indicators where immediate referral to
             secondary is indicated (NICE 2016). In addition children less than 18 years and,
             people who do not speak English and people with reduced mental capacity will be
             excluded
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: IUI Schedule in Cases of High Progesterone (NCT02447588)

Eligibility criteria:
Inclusion Criteria:

          -  Body mass index (BMI) 18-30 kg / m2

          -  Patent tubes

          -  Regular cycles (26-35 days)

          -  FSH levels on day 3 of cycle (<10 mIU / ml)

          -  Estradiol levels on day 3 of cycle (<60 pg / ml)

          -  Progesterone levels the day of hCG (> 1 ng / ml)

          -  Semen donors belonging to the bank of IVI

        Exclusion criteria

          -  Patients with ≥3 follicles of over 16 mm diameter

          -  No dominant follicle after two consecutive ultrasound

          -  Women with P <1 ng / ml on the day of hCG
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: A Study Comparing Viscosupplementation and Corticosteroid Injections for Knee Osteoarthritis (NCT01132677)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical

               -  19-75 years of age (inclusive)

               -  Symptomatic OA (1 of the following: pain, stiffness, or swelling)

               -  Evidence of grade I, II or III OA on radiographic images according to
                  Kellgren-Lawrence grading scale.

        Exclusion Criteria:

          -  Clinical

               -  Previous surgery on either knee (not including a diagnostic arthroscopy
                  arthroscopy or simple partial meniscectomy)

               -  Intra-articular treatment within the last 3 months

               -  Ipsilateral cruciate or collateral ligament injury within past 3 months, or
                  evidence of ligament laxity

               -  Inflamed knee or pronounced effusion

               -  Allergy to birds, eggs, avian proteins or known HA or corticosteroid

               -  Venous or lymphatic stasis

               -  Skin condition in the injection area

               -  Evidence of infection in the affected joint

               -  History of crystalline arthropathy or inflammatory arthritis

               -  Pregnant or nursing

               -  Third Party, Medical Legal or Workers' Compensation Board

               -  Patient unable to understand English or unable to providing informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: the Observance of Emergency Exit Treatments During the Stay of Care at the Exit of Reims Emergencies (NCT03836534)

Eligibility criteria:
Inclusion Criteria:

          -  adults

          -  consultation during the early stages of care

          -  leaving after consultation

          -  agrees to participate in the study

        Exclusion Criteria:

          -  minor patients

          -  permanently off care

          -  hospitalized patients

          -  refusal to participate in the study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Suture for Mesh Fixation in Lichtenstein Hernia Repair (NCT00815698)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy males 18-80 years

          -  Primary inguinal unilateral hernia

        Exclusion Criteria:

          -  Recurrent hernia

          -  Bilateral, scrotal or femoral hernia

          -  BMI above 35
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Objective Measure of Recovery After Outpatient Surgery (NCT02616406)

Eligibility criteria:
Inclusion Criteria:

          -  Patients presenting for outpatient inguinal hernia repair without significant medical
             comorbidities

          -  Patients who consent to participating and willing to wear device for designated time
             period per protocol

        Exclusion Criteria:

          -  History of chronic opioid use

          -  Inability to speak English

          -  Inability to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Round Spermatid Injection Protocol (NCT04053309)

Eligibility criteria:
Major Inclusion Criteria: The following are major inclusion criteria:

          1. A diagnosis of azoospermia after semen analysis.

          2. Indication to proceed with testicular sperm extraction (TESE or microTESE) based on a
             urologic evaluation.

          3. Presence of round spermatids from testicular sperm extraction (TESE or microTESE),
             irrespective of the presence or absence of mature spermatozoa.

        Major Exclusion Criteria (must not meet any): The following are exclusion criteria:

          1. Under 18 years old

          2. All patients who do not voluntarily give their written consent for participation.

          3. Men who do not wish to use their gametes (round spermatids) for fertilization of donor
             oocytes for research purposes.
Male

Subject must be at least 18 Years old.


Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Evaluation of the Acute Effect of Water-Pipe Smoking on the Respiratory System (NCT01157832)

Eligibility criteria:
Inclusion Criteria:

          -  Age > 18 Y.O.

          -  Have smoked Water-pipe at least once before.

        Exclusion Criteria:

          -  Breast feeding Women.

          -  S/P Bacterial Or Viral infection, Last 2 weeks

          -  P.O. Steroids

          -  Water-pipe smoking, last 24 hours

          -  Cigarette smoking, last 6 hours

          -  Intensive exposure to smoke (fire), last 24 hours

          -  S/P Intensive Care Hospitalization, last 3 months
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction