araag2/NLI4PR huggingface dataset:
Clinical trial: Teledermatology Versus Usual Care on Delay Before Diagnosis and Treatment of Dermatologic Conditions (NCT02122432)

Eligibility criteria:
Inclusion Criteria:

          -  Consultation with a general practitioner for any motive during which, the general
             practitioner deems necessary to obtain a dermatologic expertise for a skin lesion (for
             diagnosis or treatment)

        Exclusion Criteria:

          -  Emergency, assessed by the general practitioner (needs care or quick telephonic advice
             in the next 24 hours)

          -  Patients for which diagnosis and/or treatment are known by the general practitioner
             (the GP needs a dermatologic advice for a specific treatment (for example= laser,
             instrumental treatment...))

          -  Patient cannot go the dermatologic consultation by himself (for example: dependant
             patients...)

          -  Cognitive or psychiatric impairment (cannot give informed consent)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Entailment
Clinical trial: Bone Age Assessment in Children Using Ultrasound Compared to Wrist X-ray (NCT03123003)

Eligibility criteria:
Inclusion Criteria:

          -  Children 3.5-18 years old refered to the endocrine pediatric clinic due to short
             stature or other growth abnormalities

        Exclusion Criteria:

          -  Children with bone disease

          -  Children who within the last year took medications which might change bone metabolism
             or mineralization
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 42 Months old.
Subject must be at most 18 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: A Single Center Study to Demonstrate the Safety and Performance of Lifelight® First Software Application (NCT03998098)

Eligibility criteria:
Inclusion Criteria:

          1. Subject is informed and has been given ample time and opportunity to think about
             his/her participation and has given his/her written informed consent

          2. Subject is ≥18 years of age

          3. Subject's health status: individual is considered to be healthy (hypertension and
             hypotension is permissible. Other stable diseases at the time of testing are also
             permissible)

          4. Subject is capable of undergoing controlled hypoxaemia to the levels called for the in
             the protocol with minimal medical risk (unless only participating in the blood
             pressure study).

        Exclusion Criteria:

          1. Subject cannot expose their face fully for a reading to be taken

          2. Subject is unable to give informed consent

          3. Subject is outside of the specified age range

          4. Subject has already taken part in the study (all 4 sub studies)

          5. Subject with significant irregular heart rhythm or any disease that might affect the
             results of the study

          6. Subject is not capable of undergoing controlled hypoxia and would be placed at undue
             medical risk if this occurred

          7. Subject has any contraindications identified that would deem them unsuitable to take
             part
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Tracking IUD Bleeding Experiences: An Evaluation of Bleeding Profiles in New Intrauterine Device Users (NCT02311478)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy women ages 18-40 years with regular, normal menses (lasting between 3-7 days)
             and who are initiating an IUD

          -  Women who can provide bleeding information for 3 cycles off of any hormonal
             contraception (or non-hormonal IUD) and are willing to track bleeding for 180 days

          -  Women who are between 6 and 12 months postpartum (if they have had normal menses the
             last 3 cycles)

        Exclusion Criteria:

          -  Use of any hormonal contraceptive method in the previous 3 months

          -  Irregular duration of menstrual cycles in the last 3 cycles (<21 or >35 days)

          -  Recent history of menstrual bleeding lasting less than 3 days or greater than 7 days
             based on self report of the last 3 cycles

          -  Contraindication to use of the ParaGard® T380A IUD

          -  Mucopurulent cervicitis at the time of IUD insertion

          -  Unable to speak, read, and write in English

          -  Currently pregnant

          -  Plans for or desire for pregnancy in the next 6 months

          -  Currently breastfeeding

          -  Women who are <6 months postpartum

          -  Participation in any clinical investigation utilizing an investigational drug or
             medical device or requiring invasive gynecologic procedures within the 30 days prior
             to enrollment

          -  Wilson's disease

          -  Known coagulopathy or bleeding disorder
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Genetic Aspects of Neurologic and Psychiatric Disorders (NCT00001544)

Eligibility criteria:
INCLUSION CRITERIA:

        Individuals with selected psychiatric and neurologic disorders, including childhood onset
        schizophrenia, atypical psychosis, mental retardation, bipolar affective disorder, and
        ADHD.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 15-year-old boy with mild intellectual disability is brought to the office by his parents for a routine physical examination.  The boy is going to a school for students with learning disabilities.  The patient was adopted, and his immunizations are up to date.  Review of the patient's medical records is notable for cytogenetic studies that showed a small gap near the tip of the long arm of the X chromosome, which is consistent with fragile X syndrome, an X-linked disorder. The defect is an unstable expansion of trinucleotide repeats (CGG) in the fragile X mental retardation 1 (FMR1) gene, located on the long arm of the X chromosome. He is not using any medications and vital signs are within normal levels. His blood chemistry analysis as bellow:
Blood Chemistry Value      Normal Range     Patient Value
Glucose                    90-120 mg/dl     95 mg/dl
BUN (Blood Urea Nitrogen)  7-24 mg/dl       10 mg/dl
Creatinine                 0.7-1.4 mg/dl    0.8 mg/dl
Calcium                    8.5-10.5 mg/dl   9 mg/dl
Sodium                     134-143 mEq/L    135 mEq/L
Potassium                  3.5-4.5 mEq/L    3.7 mEq/L
Chloride                   95-108 mEq/L     98 mEq/L
CO2                        20-30 mEq/L      25 mEq/L
Blood pH                   7.38-7.42        7. 39

Patient description (patient's own words): My husband and I brought our 15-year-old son to the clinic for his routine exam. My son is going to school for special needs students. We adopted him a few years ago. His vaccinations are up to date. He already passed some chromosome testing and they found that he has a fragile X syndrome. The doctor told us that it comes from repeats in the fragile X chromosome. My son is not using any medication and his blood pressure temperature and breathing were normal during the exam. He also did a blood test. The results came back and showed that his blood sugar urea creatinine calcium sodium potassium chloride CO2 and blood pH were all within the normal range.

Does the patient match the trial criteria? Entailment
Clinical trial: Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial (NCT02363790)

Eligibility criteria:
Inclusion Criteria:

          1. Patient desires an elective surgical repair,

          2. patient is able to give informed consent,

          3. diagnosis of a midline ventral hernia with a fascial defect width on clinical
             examination or CT scan of 3-10 cm in size,

          4. body mass index <40kg/m2,

          5. candidate for LVHR based upon surgeon assessment.

        Exclusion Criteria:

          1. acute or urgent presentation,

          2. multiple defects defined as defects from two separate incisions,

          3. patient has loss of domain assessed,

          4. patient has a severe co-morbid condition likely to limit survival to <2 years,

          5. contamination noted pre-operative or intra-operative,

          6. patient is pregnant or intends to become pregnant during the study period.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Safety and Effectiveness Study for Pleurodesis With Silver Nitrate in Malignant Pleural Effusion (NCT01125124)

Eligibility criteria:
Inclusion Criteria:

          -  Malignant pleural effusion confirmed by cytologic analysis of the fluid and/or pleural
             biopsy.

          -  Recurrent and symptomatic malignant pleural effusion.

          -  Full pulmonary expansion (>90%) post thoracocentesis, confirmed via chest x-ray.

          -  Karnofsky Performance Status >30

          -  Agreement to participate of the study by signing of the Informed Consent Term.

        Exclusion Criteria:

          -  Coagulopathies (prothrombin activity <50%) and/or thrombocytopenia (<80000 count).

          -  Active pleural or systemic infection.

          -  Massive skin neoplastic infiltration.

          -  Inability of understanding the pain scale.

          -  Previous pleural procedures (except for thoracocentesis and/or pleural biopsy).

          -  Refusal to participate of the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues (NCT04714424)

Eligibility criteria:
Inclusion Criteria:

          -  Male and female patients of any race who are at least 18 years of age and can
             understand and provide verbal and written informed consent are eligible for this
             study.

        Exclusion Criteria:

          -  Patients who have had intraocular surgery less than six months ago,

          -  Potential contraindication for visual field test that include anxiety disorder,
             pregnancy, seizure disorder,cardiac pacemaker or another implantable device, severe
             vertigo or balance issues.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparison of Postoperative Pain After Hernial Sac Ligation Versus Non-ligation in Inguinal Hernioplasty (NCT04079504)

Eligibility criteria:
Inclusion Criteria:

          -  Patients ≥15 years of age, of either gender having Incomplete indirect inguinal hernia
             with or without direct concurrent hernia as mentioned in operational definition.

        Exclusion Criteria:

          -  Complete inguinal hernias.

          -  Patients having obstructed and/or strangulated inguinal hernia.

          -  Recurrent inguinal hernias.

          -  patients with ipsilateral synchronous inguinoscrotal pathologies e.g. hydrocele,
             testicular malignancy
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 15 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Contradiction
Clinical trial: Development of Novel, Biophysically Designed Fluids for Swallowing Disorders (NCT03131869)

Eligibility criteria:
Inclusion Criteria:

          -  55 years of age or older

          -  physician approval of medical stability

          -  aspiration or penetration of the laryngeal vestibule (score of 3 or higher on the
             Penetration/Aspiration Scale) or post-swallow residue in the oropharynx as
             instrumentally documented by a Speech-Language Pathologist (SLP) during a standard
             videofluoroscopic oropharyngeal swallow study

          -  capacity to provide informed consent.

        Exclusion Criteria:

          -  poorly controlled psychosis (3 or more related hospitalizations in one year

          -  refractory alcoholism (on AWD precautions)

          -  allergy to barium (used in radiographic swallowing assessment)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment