araag2/NLI4PR huggingface dataset:
Clinical trial: Bracing for Patellofemoral Osteoarthritis (NCT02984254)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with symptomatic knee OA (patellofemoral)

          -  Exclusion Criteria:

          -  Not using the brace as requested;

          -  Study abandonment;

          -  No adaptation to brace;

          -  Skin and vascular complications by use of the brace;

          -  Failure to complete the consumption of drugs between inclusion and bracing;

          -  Obesity class II, III or morbid;

          -  Patients who cannot read or understand the informed consent or the WOMAC
             questionnaire;
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Study to Investigate the Clinical Benefits of Dietary Supplement Quercetin for Managing Early COVID-19 Symptoms at Home (NCT04861298)

Eligibility criteria:
Inclusion Criteria:

          -  Patients must be 18 years of age or older, of either gender

          -  Patients must be tested positive for SARS-CoV-2 by RT-PCR

          -  Patients must exhibit typical symptoms of COVID-19 disease at screening such as fever,
             fatigue, a dry and contagious cough, loss of appetite, body aches, shortness of
             breath, mucus or phlegm, sore throat, headache, chills, sometimes with shaking, loss
             of smell or taste, congestion or runny nose, nausea, or vomiting, diarrhea, muscular
             pain etc.

          -  Patients must be in the early stage of COVID-19 disease who do not require
             hospitalisation at the time of screening

          -  Patients must be under the care of a Physician for diagnosis of COVID-19

          -  Patients who have signed informed consent

        Exclusion Criteria:

          -  Patients with proven hypersensitivity or allergic reaction to quercetin

          -  Patients with known chronic kidney disease with estimated creatinine clearance < 50
             mL/minute or need for dialysis

          -  Patients who are severely hypotensive defined as needing hemodynamic pressors to
             maintain blood pressure

          -  Patients with moderate or severe thrombocytopenia (platelet count <100 × 10⁹/L);

          -  Pregnant patients

          -  Patients declining to participate
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Impact and Burden of Rugby Injuries in Argentina. A Complete Season Retrospective Multicentric Study. (NCT04402567)

Eligibility criteria:
Inclusion Criteria:

          -  >18 years

          -  Participation in more than 80% during training and matches of the competitive season.

          -  First, intermediate, Pre-intermediate A and Pre-intermediate B categories of the
             University teams of Córdoba, Old Resian and Los Matreros, belonging to UAR member
             unions.

        Exclusion Criteria:

        - Lost patient data
Male
Accepts Healthy Volunteers



Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: D-OCT of Facial Telangiectasia Treated With IPL (NCT04274842)

Eligibility criteria:
Inclusion Criteria:

          -  legally competent,

          -  at least 18 years of age

          -  persons able to read and understand spoken and written information in Danish or
             English.

          -  One or more facial telangiectasia

        Exclusion Criteria:

          -  wounds or ulcers in area of facial telangiectasia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? Entailment
Clinical trial: Study to Assess the Safety and Patients' Satisfaction of Tears Again* in the Treatment of Dry Eye Symptoms (NCT00535054)

Eligibility criteria:
Inclusion Criteria:

          -  Suffer from at least two of the following ocular symptoms: burning, stinging,
             excessive tearing, dryness, grittiness, foreign body sensation ( including patients
             suffering from blepharitis).

          -  Use artificial tears or any other treatment for these symptoms three or more times a
             day.

        Exclusion Criteria:

          -  Known hypersensitivity to Phenoxyethanol.

          -  Pregnant and lactating women.

          -  Receive other ophthalmic medication (except for eyelid hygiene preparations).

          -  Graft-versus-host disease patients.

          -  Participated during the last month in another clinical trial.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? Contradiction
Clinical trial: Autologous Conditioned Serum: Functional and Clinical Results (NCT03850080)

Eligibility criteria:
Inclusion Criteria:

          -  knee osteoarthritis >3 months in clinical and radiographic signs

          -  VAS for pain >50mm

        Exclusion Criteria:

          -  Hepatitis B

          -  Hepatitis C

          -  HIV

          -  pregnancy

          -  drug abuse

          -  other intra-articular injections <6 months

          -  surgery on affected knee <12 months
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 35 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: EFFEKT - Efficacy and Safety of Long-term Treatment With KOGENATE Bayer/FS (NCT00874926)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with diagnosis of haemophilia A, treated with KOGENATE Bayer/FS as their only
             source of FVIII, decision taken by the investigator to administer KOGENATE Bayer/FS.
             For pretreated patients with more than 100 exposure days an inhibitor assessment
             within three months prior to enrollment should be available; for pretreated patients
             with less than 100 exposure days an inhibitor assessment at baseline should be
             available.

        Exclusion Criteria:

          -  Exclusion criteria must be read in conjunction with the local product information.
Male
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Famotidine in Subjects With Non-erosive Gastroesophageal Reflux Disease (NCT00141960)

Eligibility criteria:
Inclusion Criteria:

          -  Patients have heartburn with non-erosive gastroesophageal reflux disease.

        Exclusion Criteria:

          -  Patients have diseases which interfere with evaluation of the efficacy and safety in
             this study.

          -  Patients are receiving and/or have received prior to the enrollment the treatment
             which interfere with evaluation of the efficacy and safety in this study.

          -  Patients have severe cardiovascular, hepatic, renal and hematological disorders.

          -  Patients are allergic to or have a history of drug allergy to H2RA.

          -  Patients have or have a history of malignant tumors.

          -  Patients are pregnant or a lactating mother.

          -  Patients have participated in other clinical studies less than 12 weeks prior to
             submitting the informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Poor Ovarian Stimulation Response in In Vitro Fertilization (IVF) Program (NCT02640976)

Eligibility criteria:
Inclusion Criteria:

          -  Women at or under the age of 35 years.

          -  Normal thyroid stimulating hormone and prolactin levels.

          -  Normal ovulatory cycles (25-35 interval days), together with proven patent fallopian
             tubes at hysterosalpingography or laparoscopy done within six cycles preceding the
             ICSI cycle.

          -  Presence of both ovaries with normal findings as assessed by trans-vaginal ultrasound
             and laparoscopy.

          -  All male partners had a normal semen analysis according to WHO criteria (WHO, 2010),
             done within 6 months preceding the ICSI cycle

        Exclusion Criteria

          -  Chronic medical disorders such as diabetes.

          -  Previous inadequate response to ovulation induction.

          -  Polycystic ovary syndrome.

          -  Women who performed ovarian surgery and cases of endometriosis diagnosed by
             laparoscopy or suspected by ultrasound or CA-125 assay.

          -  Abnormal pelvic pathology or congenital anomalies.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Accuracy of Swallowing Disturbance Questionnaire in Screening Inpatient Elderly (NCT03816098)

Eligibility criteria:
Inclusion Criteria:

          -  (1) age over 65 years old; (2) does not use enteral tube feeding; (3) no serious
             mental or cognitive conditions; no aphasia

        Exclusion Criteria:

          -  (1) age under 65; (2) use enteral tube feeding; (3) subjects with serious mental or
             cognitive conditions or aphasia (4) Allergy to barium sulfate suspension
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment