Clinical trial: EFFECT OF FLOW RESTRICTION ON BONE QUALITY WITHIN A MULTICOMPONENT EXERCISE PROGRAM FOR OLDER WOMEN WITH OSTEOPOROSIS. (NCT04760145)

Eligibility criteria:
Inclusion Criteria:

          -  A woman between 60 and 75 years of age with a medical diagnosis of osteoporosis by
             means of a femur or lumbar densitometry of less than 2.5 standard deviations (SD) of
             peak bone mass.

          -  No history of previous fracture in the last 10 years.

        Exclusion Criteria:

          -  Secondary osteoporosis.

          -  Having suffered a bone fracture in the last year.

          -  Present primary osteoporosis but who presented juvenile osteoporosis in adolescence or
             youth.

          -  Uncontrolled arterial hypertension.

          -  Severe acute respiratory failure.

          -  Uncontrolled orthostatic hypotension.

          -  Diabetes mellitus with acute decompensation or uncontrolled hypoglycemia.

          -  Endocrine, hematological and other associated rheumatic diseases.

          -  Mental health problems (schizophrenia, dementia, depression, etc.) or not being in
             full mental capacity.

          -  Patients with pharmacological treatments of glucocorticoids, anticoagulants and/or
             diuretics.

          -  Patients with coagulation problems or previous cardiac pathology.

          -  People with a body mass index (BMI) equal to or higher than 30.

          -  Subjects who present a systemic disease or any other pathology in which therapeutic
             exercise could be contraindicated.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 60 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction