araag2/NLI4PR huggingface dataset:
Clinical trial: Structured Non-operative Treatment of Knee Osteoarthritis (NCT01535001)

Eligibility criteria:
Inclusion Criteria:

          -  Knee-OA detected by x-ray (Kellgren & Lawrence grade 1 or greater)

          -  KOOS4 of ≤ 75

          -  Considered not to be a candidate for Total Knee Replacement (TKR) by the orthopedic
             surgeon.

          -  The participant is > 18 years of age.

          -  The participant can provide relevant and adequate, informed consent.

        Exclusion Criteria:

          -  Prior TKA ipsilateral

          -  Rheumatoid arthritis

          -  Mean VAS > 60mm the last week on a 0-100mm scale

          -  Possible pregnancy or planning pregnancy;

          -  Inability to comply with the protocol;

          -  Inadequacy in written and spoken Danish.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: A 5-Year Follow-up Study Investigating Factors Associated With Osteoporotic Fracture in Chinese Postmenopausal Women (NCT02247011)

Eligibility criteria:
Inclusion Criteria:

          1. postmenopausal women (normally over 50 years old and years since menopause over than 1
             year) in Peking.

          2. participants without any fracture in 2007 PK-VF study were included in the prospective
             study investigating the association of bone turnover markers/BMD/25(OH)D with fracture
             incidence.

        Exclusion Criteria: participants with years since menopause less than 1 year.
Female
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 108 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Austrian COVID-19 Registry (NCT04351529)

Eligibility criteria:
Inclusion Criteria:

          -  Age >=18 years

          -  Positive test for SARS-CoV-2

        Exclusion Criteria:

          -  Due to the non-interventional design of the registry there are no specific exclusion
             criteria.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Ultrasonography of the Neuromuscular Degeneration Behavior in Amyotrophic Lateral Sclerosis (NCT03683875)

Eligibility criteria:
Inclusion Criteria:

          -  Definite ALS

        Exclusion Criteria:

          -  Primary Lateral Sclerosis (PLS)

          -  Other forms of motor neuron disorders
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient description (patient's own words): I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Does the patient match the trial criteria? Entailment
Clinical trial: BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A (NCT00623727)

Eligibility criteria:
Inclusion Criteria:

          -  Males aged 12 to 70 years

          -  Subjects with severe hemophilia A (< 1% factor VIII [FVIII]:C)

          -  Subjects with equal or greater than 150 exposure days (EDs) with any FVIII in total

          -  Subjects who have been on-demand treatment with a minimum of 1 relevant bleed per
             month or have been on secondary prophylaxis treatment with not more than a 3x/week
             schedule

          -  Subjects with bleeding events and/or treatments during the last 6 months prior to
             study entry which are documented in the subjects medical records

          -  Subjects with no measurable inhibitor activity

          -  Subjects with no history of FVIII inhibitor antibody formation

          -  Written informed consent by subject and parent / legal representative, if < 18 years

        Exclusion Criteria:

          -  Subjects who are receiving primary prophylaxis

          -  Subjects on prophylaxis with documented requirements of > 75 IU/kg/week

          -  Subjects with any other bleeding disease beside hemophilia A (i.e., von Willebrand
             disease)

          -  Subjects with abnormal renal function

          -  Subjects with elevated hepatic transaminases

          -  Subjects on treatment with immunomodulatory agents within the last 3 months prior to
             study entry or during the study

          -  Subjects with known hypersensitivity to the active substance, mouse or hamster
             protein, liposomes or polyethyleneglycol (PEG)

          -  Subjects who require any pre-medication for FVIII injections
Male
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effects of Kinesio-taping in Knee Osteoarthritis Patients. (NCT04585373)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with unilateral and bilateral knee OA

          -  O.A with grade 2-3(Kellgren and Lawrence system for classification of osteoarthritis
             of knee)

          -  Experiencing Pain for more than 1 month

        Exclusion Criteria:

          -  Rheumatic diseases, inflammatory arthritis, septic arthritis

          -  Intra-articular corticosteroid injection during the past month

          -  Patients with fracture

          -  Patients with any carcinoma

          -  if patient having any other systemic illness.

          -  Allergic reaction to KT
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: The Simple ECG Monitoring Trial (Comparison of a Novel Recording System With a Standard Holter Monitor) (NCT01382953)

Eligibility criteria:
Inclusion Criteria:

          -  Syncope of uncertain etiology or

          -  Pre-syncope of uncertain etiology or

          -  Palpitations of uncertain etiology or

          -  Management of known AF/SVT patients

        Exclusion Criteria:

          -  Any abnormal or friable skin over the anterior thorax and upper abdomen

          -  Sternal incision within 3 months from the date of enrollment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: Effects of Pulmonary Rehabilitation on Functional and Health Status Measures in Pulmonary Fibrosis (NCT03542318)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with a confirmed diagnosis of Pulmonary Fibrosis

          -  Patients had to be medically stable to participate in such a programme

        Exclusion Criteria:

          -  Any orthopaedic or neurological condition affecting mobility

          -  If they required oxygen therapy this had to be used
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.


Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparison of TLH and LAVH With Over Than 500g (NCT03146299)

Eligibility criteria:
Inclusion Criteria:

          -  Have the indication for hysterectomy for a supposed benign uterine disease

          -  Have a giant uterus of 500g or more

          -  Estimation of uterine weight more than 500g

          -  Uterine myoma size at 4 months or more after pregnancy due to pelvic examination

          -  The length of the long axis of one uterine myoma is more than 8cm or the length of the
             long axis for over 2 uterine myomas is more than 6cm

          -  Have been not pregnant at the time of presentation

          -  Have been appropriated medical status for laparoscopic surgery (surgery (American
             Society of Anesthesiologists Physical Status classification 1 or 2)

        Exclusion Criteria:

          -  Have a suspicion of malignancy or malignant tumors (cervical cancer, ovarian cancer,
             fallopian tube cancer, peritoneal cancer, Endometrial cancer)
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair (NCT01273818)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of inguinal hernia

        Exclusion Criteria:

          -  Femoral hernia

          -  Emergency cases
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Utility of the History and Physical Exam in the Emergency Department (NCT01154517)

Eligibility criteria:
Inclusion Criteria:

          -  Anyone over the age of 18 with a generalized complaints able to provide consent

        Exclusion Criteria:

          -  Anyone under 18 yrs and anyone with a very specific, system based complaint.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Contradiction