araag2/NLI4PR huggingface dataset:
Clinical trial: Endoscopic Unroofing for Small Gastric SETs (NCT02587923)

Eligibility criteria:
Inclusion criteria:

        -) subjects with small gastric subepithelial tumors who underwent endoscopic unroofing

        Exclusion criteria:

        -) none
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Arthroscopic Treatment of Resistant Cases of Patellofemoral Pain (NCT03615976)

Eligibility criteria:
1. Inclusion criteria:

               1. Age between 18 to 50

               2. Ant. Knee pain

               3. Resistant cases to medical and physiotherapy after 6 months.

               4. Intact tibiofemoral joints or early O.A , and intact meniscus, cruciate
                  ligaments, and Collateral ligaments.

          2. Exclusion criteria:

               1. Old Age >50 or < 18

               2. Combined cases with severe tibiofemoral OA (either deformity or malignment).

               3. Combined injury to (collateral ligaments, meniscus, cruciate ligament)

               4. Cases with tibial torsion

               5. Malalignment that necessitate correction.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction (NCT00001724)

Eligibility criteria:
Patients of either sex requiring removal of two impacted mandibular third molars (partial
        bony or soft tissue impaction).

        16 years of age of older.

        Indicates willingness to undergo oral surgery with local anesthesia and intravenous
        midazolam only.

        Willing to return for the removal of the remaining maxillary third molars at a second
        appointment.

        Patients with a history of allergy to flurbiprofen, aspirin, or any NSAID will be excluded.

        Those with a history of aspirin or NSAID-induced asthma will be excluded.

        Females of childbearing potential who are not practicing adequate contraception will be
        excluded.

        Pregnant or nursing females will be excluded.

        Patients with recent history or present signs of renal, hepatic, endocrine, pulmonary,
        cardiac, gastrointestinal, neurologic, or cerebral function impairment will be excluded.

        Those with psychiatric disorders will be excluded.

        Patients who have taken an investigational drug within 30 days of this study will be
        excluded.

        Those who have taken another analgesic, steroid, opioid, or NSAID within 24 hours prior to
        the study will be excluded.

        Those with an absence of bilateral local anesthesia during surgery as evidenced by
        anesthesia or paresthesia of the lower lip postoperatively will be excluded.

        Patients who use drugs which will interact with NSAID such as aspirin, warfarin,
        probenecid, methotrexate, lithium and diuretics will be excluded.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Covid-19 Triage Using Camera-based AI (NCT04383457)

Eligibility criteria:
Inclusion Criteria:

          1. The patient is attending for triage presenting with symptoms of an infection.

          2. Subject has provided informed consent

          3. Age ≥18 years

          4. Fluent in Swedish (reading, writing, conversational)

          5. Mental state is such that he or she is able to understand and give informed consent to
             participation in the study by signing the Information and Consent Form

          6. The investigator determines that the new method, and the reference methods, can be
             used as intended with adequate reliability and safety

          7. The time for investigations in this study is estimated to approximately 15-20 minutes.
             Vital signs will be handed over to the care provider responsible for the further
             management of the patient saving approximately 5-10 minutes of their time. Hence, the
             delay in the management of each patient introduced by this study is approximately 10
             minutes. Patients deemed being in such a severe medical condition on arrival, that 10
             minutes of delay is deemed detrimental will not be included.

        Exclusion Criteria:

          1. Depressed level of consciousness from inclusion up until all investigations are
             completed (during approximately 15-20 minutes).

          2. Patient request to be withdrawn from the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Phase II Exploratory Clinical Study of KUX-1151 (NCT02190786)

Eligibility criteria:
Inclusion Criteria:

          -  Japanese HU patients (Outpatient)

          -  Patients who meet the following criteria concerning serum uric acid levels at the
             screening [1) Gout: > 7.0 mg/dL, 2) HU with complications: ≥ 8.0 mg/dL, 3) HU without
             complications: ≥ 9.0 mg/dL]

        Exclusion Criteria:

          -  Patients who have any symptom of gouty arthritis within 2 weeks of investigational
             product administration
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 64 Years

Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessment of the Risk of Inhibitor Formation in Previously Treated Patients With Severe Hemophilia A (NCT00621673)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects with severe hemophilia A (< 2% FVIII:C)

          -  Subjects with no history of FVIII inhibitor antibody formation

          -  Subjects with no measurable inhibitor activity

          -  Subjects with at least 200 EDs with FVIII concentrate in total, including 20 EDs in
             the previous 6 months

          -  Subjects whose current treatment with any CHO rFVIII product

          -  Subjects with no elective surgery and/or continuous infusion FVIII administration is
             foreseen during the study

          -  Subjects with normal prothrombin time (PT), partial thromboplastin time (PTT)
             compatible with FVIII deficiency

        Exclusion Criteria:

          -  Subjects with any other bleeding disease beside hemophilia A (i,e., von Willebrand's
             disease)

          -  Subjects who have known intolerance or allergic reactions to constituents of rFVIII-FS
             or known hypersensitivity to mouse or hamster proteins

          -  Any individual with a past history of severe reaction(s) to FVIII concentrates

          -  Subjects on treatment with immunomodulatory agents within the last 3 months prior to
             study entry

          -  Subjects who were receiving or had received other experimental drugs within 3 months
             prior to study entry

          -  Subjects who require any medication for FVIII infusions
Male
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Impact of Folates in the Care of the Male Infertility (NCT01407432)

Eligibility criteria:
Inclusion Criteria:

          -  Couple whose man is from 18 to 60 years old

          -  Couple whose man presents an infertility indicating a care in VITRO fertilization with
             or without intracytoplasmic sperm injection (IVF +/- ICSI)

          -  Couple whose spouse is from 18 to 38 years old

          -  Couple whose spouse do not present particular factors of infertility

          -  Couple Taken care in IVF +/- ICSI

          -  Couple with social insurance

          -  2 members of the couple having signed the consent

        Exclusion Criteria:

          -  Etiology of not genetic known male infertility : infertility of neoplastic origine,
             infertility of definitive obstructive origin

          -  Presence of a factor of feminine infertility : A definitive infertility tubal, Turned
             out ovarian incapacity (FSH > 9 and/or CFA <= 8)

          -  Male infertility requiring the appeal to some sperm testicular or in some frozen
             sperm- Men or women attend of HIV or hepatitis B or C

          -  Epileptic men

          -  Men under anti-folic treatment

          -  Men presenting a big sensibility to the folic acid or to one of the constituents of
             the drug

          -  Couple of which one of the partners refuses to participate in the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient description (patient's own words): I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Does the patient match the trial criteria? Entailment
Clinical trial: Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature (NCT00355030)

Eligibility criteria:
Inclusion Criteria:

          -  male or female children with ISS

          -  age greater than or equal to 8 years and less than or equal to 12 years and 3 months
             for girls and greater than or equal to 9 years and less than or equal to 14 years and
             3 months for boys

          -  bone age less than or equal to 12.0 years for girls and less than or equal to 14.0
             years for boys based on a central reading of an X-ray of the left hand and wrist

          -  Pubertal stage B2 and B3 for girls based on the Tanner method

          -  Pubertal stage G2 and G3 for boys based on the Tanner method

        Exclusion Criteria:

          -  Growth hormone deficiency (GHD)

          -  Insulin-like growth factor-I levels greater than 3 SDS

          -  Chromosomal abnormality diagnosed locally on a karyotype. For girls, the karyotype to
             eliminate a Turner syndrome, is mandatory

          -  Small for gestational age (SGA)

          -  Has reached menarche (had her first menstrual period)

          -  Have any significant concomitant disease that is likely to interfere with growth or
             with the study, or is a known contraindication to Growth Hormone treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 8 Years old.
Subject must be at most 171 Months

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls (NCT01169103)

Eligibility criteria:
Inclusion Criteria:

          -  Adolescent girls 13-21 years old with bone age ≥ 14 years

          -  Overweight girls: Body Mass Index (BMI) greater than the 95th percentile for age

          -  Waist/Hip ratio ≥ 0.85

          -  Insulin Like Growth Factor -1 (IGF-1) below -0.5 standard deviations (SD) for pubertal
             stage or age

        Exclusion Criteria:

          -  Pregnancy (positive pregnancy test) prior to enrollment in the study

          -  Significant weight gain or loss within 3 months of study (more than 5 kg)

          -  Use of medications that affect GH or cortisol levels (such as estrogen including oral
             contraceptive pills, oral glucocorticoids)

          -  Use of medications such as Meridian and Orlistat

          -  Presence of diabetes mellitus

          -  Uncontrolled Thyroid disorders

          -  Chronic renal insufficiency

          -  Participation in another simultaneous medical investigation or trial

          -  Active neoplasm or history of cancer

          -  Prader-Willi syndrome

          -  History of scoliosis if bone age is <15 years

          -  Hypersensitivity to rhGH or constituents of the injections
Female
No healthy subjects accepted to join the trial.
Subject must be at least 13 Years old.
Subject must be at most 21 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: PRF in Management of Chronic Multiple Oral Ulcers (NCT03878771)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with Oral ulcers due to Benin mucous membrane pemphioid, Pemphius vulgaris
             and Steven Johnson's Syndrome with mucositis score 4 and pain score 10

        Exclusion Criteria:

          -  patients with any systemic other systemic condition
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction