araag2/NLI4PR huggingface dataset:
Clinical trial: Acceptability, Feasibility and Preliminary Impact of OurPlan, an mHealth HIV Prevention Intervention for Male Couples (NCT04836091)

Eligibility criteria:
Inclusion Criteria for both partners of the male couple:

          -  self-reported that currently self-identifies as a male

          -  self-reported in a sexual relationship with another self-identified male

          -  self-reported relationship length between 1 and 12 months

          -  self-reported anal sex with relationship partner in past 2 months

          -  owns and uses an Internet-connected smartphone or tablet

          -  resides in the U.S.

          -  self-reported ability to read and understand English-language

        Exclusion Criteria:

          -  Does not meet one or more the inclusion criteria
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: Nutritional Stimulation of Growth in Children With Short Stature Without Growth Hormone Deficiency (NCT04226586)

Eligibility criteria:
Inclusion Criteria:

          -  Ages 3 to 11 years (inclusive).

          -  Must have had normal growth hormone (GH) response (i.e., peak GH concentration ≥10
             ng/mL) to GH provocative tests such as Arginine Insulin Tolerance Test (AITT) or
             Arginine Clonidine Tolerance Test (ACTT).

          -  Pre-pubertal status (i.e. Tanner stage 1 for breast development for girls and
             testicular enlargement for boys and pubic hair for both sexes).

        Exclusion criteria:

          -  Ages younger than 3 years or older than 11 years.

          -  Medical history of a neurologic, endocrinologic, genetic, or metabolic problem known
             to have a direct effect on height growth. This includes, but is not limited to,
             children with Down syndrome, Turner syndrome, Russel-Silver syndrome, Prader-Willi
             syndrome, Pseudohypoparathyroidism, chronic kidney disease, malabsorptive syndromes,
             cancer survivors, etc.

          -  Currently being treated or previously treated with Growth hormone, or history of oral
             steroid treatment within the last 3 months.

          -  Being in puberty.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 3 Years old.
Subject must be at most 11 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: Characteristics of Patients and Healthcare Workers With COVID-19 in Meta State, Colombia (NCT04456426)

Eligibility criteria:
Inclusion Criteria:

          -  Patients admitted to participant institutions with respiratory symptoms or diagnosed
             as compatible with COVID-19.

        Exclusion Criteria:

          -  None.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.

Subject must be at most 120 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Sensitivity and Specificity of Color Doppler Directed Temporal Artery Biopsy as Compared to Standard Random Biopsy in the Diagnosis of Temporal Arteritis (NCT00361192)

Eligibility criteria:
Inclusion Criteria:

          -  Patients suffering from signs and symptoms consistent with TA and who have not
             undergone previous temporal artery biopsy will be included.

        Exclusion Criteria:

          -  Patients suffering from isolated polymyalgia rheumatica will be excluded.

          -  Patients who are already undergoing steroid treatment will be excluded.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient description (patient's own words): I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Does the patient match the trial criteria? Contradiction
Clinical trial: Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) (NCT04102930)

Eligibility criteria:
Inclusion Criteria:

          -  Willing to self-identify an ethnic group, such as Caucasian, Asian, Afro-Caribbean.

          -  Have a firm clinical diagnosis of GCA or PMR, or (for patients identified
             prospectively) GCA or PMR should be more likely than any alternative explanation for
             the patient's symptoms.

          -  Able and willing to give informed consent. Patients will be 50 years of age or over,
             unless both biopsy-proven and a clinically classical case of GCA.

        Exclusion Criteria:

        • Patient unwilling or unable to give fully informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient description (patient's own words): I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Does the patient match the trial criteria? Entailment
Clinical trial: Wrist Arthroscopy Study (NCT04457362)

Eligibility criteria:
Inclusion Criteria:

          1. Age > 18 years.

          2. Wrist pathology based on clinical examination/imaging studies undergoing wrist
             arthroscopy for further evaluation/treatment.

          3. Willingness to participate in the study

        Exclusion Criteria:

          -  1. Age < 18 years.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Laparoscopic Hysterectomy With Prior Uterine Artery Ligation (NCT04522232)

Eligibility criteria:
Inclusion Criteria: any benign uterine pathology such as:

          -  fibroid uterus

          -  endometrial hyperplasia with failed hormonal therapy

          -  DUB with failed medical and hormonal treatment

          -  uterine prolapse.

        Exclusion Criteria:

          -  gynecologic malignancy

          -  presence of contraindications to laparoscopy.
Female
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Can We Predict Who Has Gastroesophageal Reflux Disease (GERD)? (NCT01204931)

Eligibility criteria:
Inclusion Criteria:

          -  Male and female subjects ages 18 or older

          -  Presenting to the Vanderbilt GI outpatient clinic with symptoms of GERD

          -  Undergoing upper endoscopy and wireless pH monitoring (standard of care)

          -  Erosive disease: presence of esophageal mucosal injuries documented

          -  Non-erosive disease: normal esophagogastroduodenoscopy (EGD) with symptoms

          -  Control group: normal subjects without symptoms of GERD

        Exclusion Criteria:

          -  Anti-reflux therapy within 7 days prior to the pH study

          -  Previous neck, esophagus, or stomach surgery

          -  Major motility disorders

          -  Previous neck, esophagus, or stomach cancer or radiations
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis (NCT03781908)

Eligibility criteria:
Inclusion Criteria:

          1. Unilateral symptomatic recurrent malignant pleural effusion patients who fulfill the
             criteria for pleurodesis (i.e. positive pleural biopsy or cytology for malignancy, a
             Karnofsky index score of more than 60 and life expectancy of more than one year).

          2. Rapidly accumulated undiagnosed pleural effusion .

          3. Age : 30-75 years old.

        Exclusion Criteria:

          1. Transudative pleural effusion.

          2. Exudative pleural effusion due to causes other than malignancy ( i.e. parapnuemonic ,
             post-tuberculous pleural effusion )

          3. Presence of hemorrhagic diathesis ( prothrombin time <50% and platelet count
             <80,000/mm 3 )

          4. Active pleural or systemic infection.

          5. Neoplastic infiltration of the skin at the site of pleural catheter insertion.

          6. Malignant pleural effusion with trapped lung or loculated pleural effusion.

          7. Previous lobectomy or pneumonectomy on the affected side.

          8. Karnofsky index score> 50.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Progesterone Versus Progesterone Plus Dydrogesterone in FET (NCT03998761)

Eligibility criteria:
Inclusion Criteria:

          -  Undergoing frozen embryo transfer

          -  Endometrial prepared by exogenous hormonal regimen

          -  Permanent resident in Vietnam

        Exclusion Criteria:

          -  Having > 2 embryo transfer attempts

          -  Having embryo(s) from donors cycles

          -  Having embryo(s) from IVM

          -  Having embryo(s) from PGT/PGS

          -  Having endometrial abnormalities: polyp, sub-mucosal fibroid, cesarean scar defects,
             endometrial hyperplasia, endometrial fluid accumulation, endometrial adhesion.

          -  Participating in another IVF study at the same time
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Transient Lower Esophageal Sphincter Relaxations and High Resolution Manometry (NCT00931593)

Eligibility criteria:
Inclusion Criteria:

          1. Male or Female between 18 and 60 years

          2. Subject without typical or atypical symptoms of gastro-esophageal reflux disease
             (heartburn, regurgitation, epigastric pain, chest pain, chronic cough, pharyngeal
             pain)

          3. Subject without any medication (except oral contraception)

          4. Subject without previous digestive surgery history (except appendicectomy)

          5. Capability to pass manometric probes through each nostril

          6. Subject with health insurance

          7. Written informed consent

          8. No participation to another study at the same time

        Exclusion Criteria:

          1. Age under 18 years or upper 60

          2. Pregnant woman or lactation

          3. Incapability to give consent

          4. No written informed consent
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction