Clinical trial: Accuracy of Pulse Oximeters With Profound Hypoxia (NCT02571686)

Eligibility criteria:
Inclusion Criteria:

          1. The subject is male or female, aged ≥18 and <50.

          2. The subject is in good general health with no evidence of any medical problems.

          3. The subject is fluent in both written and spoken English.

          4. The subject has provided informed consent and is willing to comply with the study
             procedures.

        Exclusion Criteria:

          1. The subject is obese (BMI>30).

          2. The subject has a known history of heart disease, lung disease, kidney or liver
             disease.

          3. Diagnosis of asthma, sleep apnea, or use of CPAP(Continuous positive airway pressure).

          4. Subject has diabetes.

          5. Subject has a clotting disorder.

          6. The subject a hemoglobinopathy or history of anemia, per subject report or the first
             blood sample, that in the opinion of the investigator, would make them unsuitable for
             study participation.

          7. The subject has any other serious systemic illness.

          8. The subject is a current smoker.

          9. Any injury, deformity, or abnormality at the sensor sites that in the opinion of the
             investigators' would interfere with the sensors working correctly.

         10. The subject has a history of fainting or vasovagal response.

         11. The subject has a history of sensitivity to local anesthesia.

         12. The subject has a diagnosis of Raynaud's disease.

         13. The subject has unacceptable collateral circulation based on exam by the investigator
             (Allen's test).

         14. The subject is pregnant, lactating or trying to get pregnant.

         15. The subject is unable or unwilling to provide informed consent, or is unable or
             unwilling to comply with study procedures.

         16. The subject has any other condition, which in the opinion of the investigators' would
             make them unsuitable for the study -
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction