Clinical trial: Prevalence of Myocardial Scars on CMR After COVID-19 Infection (NCT04636320)

Eligibility criteria:
Inclusion Criteria:

          -  Man or woman ≥ 18 years old

          -  Affiliated to a health insurance program

          -  Providing free, informed, written and signed consent to participate (at the latest on
             the day of inclusion and before any research procedure is initiated)

          -  Effective contraception if women in the age to procreate

          -  In the patient group : history of COVID-19 infection with either a positive Reverse
             Transcriptase Polymerase Chain Reaction (RT-PCR) test on nasopharyngeal swab or a
             positive COVID-19 serology in the acute stage. Presence of all following symptoms in
             the acute stage: fever>38°C, asthenia, arthromyalgia, associated with at least 2 of
             the following: coughing and/or spitting, dyspnea and/or chest discomfort, anosmia
             and/or ageusia.

        Exclusion Criteria:

          -  age < 18 years old

          -  History of cardiac disease or acute coronary syndrome associated with troponin rise

          -  History of allergic reaction to gadolinium-based contrast agents

          -  History of severe renal failure

          -  Presence of a pacemaker, implantable defibrillator, intra-orbital metallic material,
             intra-cranial surgical clip, valve prosthesis Star-Edwards pre 6000, neurostimulator
             or implantable insulin pump

          -  Claustrophobia or inability to lay on the back for 50 min

          -  Pregnant or breast feeding women

          -  Inability to express informed consent

          -  Person deprived of liberty by judicial or administrative decision

          -  Person under legal protection

          -  In the healthy volunteer group:

               -  Symptoms suggestive of COVID-19 infection over the epidemic period (after
                  February 1st 2020)

               -  Person not willing to be informed of potential incidental CMR findings

          -  In the patient group:

               -  Hospitalization for infectious syndrome suggestive of COVID-19.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction