araag2/NLI4PR huggingface dataset:
Clinical trial: Parent-Based Treatment for Pediatric Overweight (NCT00807560)

Eligibility criteria:
Inclusion Criteria:

          -  Ages 13-17

          -  Male and female

          -  Living with at least one parent or guardian who is willing to participate in treatment

          -  A BMI percentile >85% for gender and age (e.g., overweight or at risk for overweight)

        Exclusion Criteria:

          -  Current psychotic illness

          -  Current alcohol/drug dependence

          -  Active suicidality

          -  Eating disorders (e.g., binge eating disorder)

          -  History of bariatric surgery

          -  Medication associated with significant weight changes (e.g., antipsychotics)

          -  Serious medical or physical conditions resulting in significant weight changes (e.g.,
             pregnancy, genetic disorders).

          -  Complications of obesity that contraindicate moderate physical activity (e.g.
             orthopedic disorders)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 13 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: Study of the Response of Human Small Blood Vessels (NCT00001622)

Eligibility criteria:
Patients (men and nonpregnant women) with systemic hypertension, patients with
        hypercholesterolemia, and normal volunteers.

        All blood pressure recordings must be consistently elevated.

        No renovascular hypertension or other etiologies for elevated blood pressure.

        No definite evidence of accelerated or malignant hypertension (diastolic pressures above
        115 mmHg, with associated encephalopathic changes, papilledema, progressive renal failure,
        or congestive heart failure), or serious intercurrent illness.

        Patients in whom withdrawal of antihypertensive medications is considered hazardous are
        ineligible.

        Patients in whom the blood pressure remains at normal levels 2 weeks after withdrawal of
        antihypertensive treatment will be closely monitored until they become hypertensive, at
        which time they will undergo the study. Patients in whom blood pressure does not increase
        after 2 months of discontinuation of therapy will be excluded from the study.

        Patients with coexistent hypertension and hypercholesterolemia are ineligible.

        Normal volunteers who are not taking any kind of medication are eligible.

        No history of diabetes, peripheral vascular disease, coagulopathy, or any other disease
        predisposing to vasculitis or Raynaud's phenomenon.

        No history of keloid formation.

        All patients must be capable of giving informed consent for all procedures.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Contradiction
Clinical trial: Patient's Pretreatment Expectations About Post-Lyme Symptoms (NCT03462329)

Eligibility criteria:
Inclusion Criteria:

          -  erythema migrans

        Exclusion Criteria:

          -  pregnancy or lactation

          -  immunocompromised

          -  taking antibiotic with antiborrelial activity within 10 days
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 31-year-old woman comes to the office due to 3 days of rash on her left arm.  The lesion is mildly pruritic but not painful.  She is otherwise healthy and occasionally takes ibuprofen during the first few days of her menstrual period.  Temperature is 37 C, blood pressure is 110/75 mm Hg, and pulse is 95/min. The lesion is like a target sign known as erythema migrans. She recently went for an adventure trip in New Hampshire. The patient is diagnosed with Lyme disease.

Patient description (patient's own words): I went to the clinic because I had a rash on my left arm for three days, and the lesion started to be putrid, but it was not painful. I'm a 31-year-old healthy woman and the only medication I use is ibuprofen when I get my periods. They took my temperature, which turned out to be 37°C and took my blood pressure which was 110/75 and my pulse 95. My lesion is round like a target sign. I just came back from a New Hampshire road trip with my friends. Unfortunately, the doctor diagnosed me with Lyme disease.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Intrauterine Navigation Using Intrauterine Insemination Catheter for Mock Embryo Transfer Prior to Day 3 Embryo Transfer on Pregnancy Rate: A Pilot Study (NCT03358732)

Eligibility criteria:
Inclusion Criteria:

        We included nulliparous patients who were < 42 years of age with body mass index (BMI) < 30
        kg/m2 and normal endometrial cavity, used fresh sperm or oocytes, had two or more embryos
        available for transfer on day 3 post ovum pick-up (OPU), and no more than 3 previous
        unsuccessful ART cycles

        Exclusion Criteria:

        Patients with uterine fibroids, uterine anomalies, intra-uterine adhesions, and uterine
        polyps, patients with chronic diseases in the as uncontrolled diabetes or hypertension, or
        if the patient had difficult mock ET . patients with severe male factors for infertility
        requiring surgical retrieval of sperms were excluded from the study.

        -
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 42 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Registry of Patients With Von WilLEbrand Disease Treated With Voncento® (NCT04657887)

Eligibility criteria:
Inclusion Criteria:

          -  Patients suffering from constitutional von Willebrand disease for whom Desmopressin
             treatment is deemed ineffective or contraindicated

          -  Patients suffering from von Willebrand disease and being treated or having been
             treated with Voncento® for the treatment of surgical and non-surgical bleeding
             episodes, the prophylaxis of surgical and non-surgical bleedings

          -  Patients with no history or suspicion of inhibitors (judged on previous efficacy)

        Exclusion Criteria:

          -  Refusal of the patient or the patient's legal representative to take part in the
             study;

          -  Existence of a contraindication to the use of Voncento® treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Therapeutic Exercise in Patients With Hemophilia (NCT04114448)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of hemophilia type A or hemophilia type B.

          -  Knee, elbow or ankle arthropathy caused by hemophilia

          -  Pharmacological treatment based on using VIII or IX factor concentrates.

        Exclusion Criteria:

          -  Presence of VIII FIX inhibitors.

          -  Having received anti-inflammatory treatment using Arcoxia (Etoricoxib)

          -  Having undergone a surgical intervention at the target joint.

          -  Patients enrolled in other research which implies doing physical exercise.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Serum Kisspeptin: a Predictive Marker of Miscarriage or Not? (NCT03940495)

Eligibility criteria:
Inclusion Criteria:

          -  Women who have a positive pregnancy test following IVF or frozen-thawed transfer

        Exclusion Criteria:

          -  Women with renal failure are excluded due to assay interference with kisspeptin
             measurement
Female
No healthy subjects accepted to join the trial.



Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: COVID-19 Endoscopy Survey (NCT04342637)

Eligibility criteria:
Inclusion Criteria:

          -  physicians working in endoscopy units worldwide

        Exclusion Criteria:

          -  physicians not working in endoscopy units worldwide
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 70 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Wrist-used Blood Pressure Monitor Clinical Test (Cuff Range: 14cm-25cm) (NCT00952965)

Eligibility criteria:
Inclusion Criteria:

          -  wrist circumference: 14 cm-25 cm

        Exclusion Criteria:

          -  none
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 23 Years old.
Subject must be at most 81 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: Short Stature Related Distress (NCT01246219)

Eligibility criteria:
Inclusion Criteria:

        1 Segment 1 :Boys at the age range of 8-13 years 2. Segment 2: Boys at the age range of
        12-17 years 3. Tanner stage 1 (segment 1 only) 4. more than 2 SD's (standard deviation)
        below the average height

        Exclusion Criteria:

          1. Mental retardation,

          2. Psychiatric illness,

          3. Lack of informed consent\assent.

          4. Health status that required chronic treatment with steroids
Male
No healthy subjects accepted to join the trial.
Subject must be at least 8 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 15-year-old boy with mild intellectual disability is brought to the office by his parents for a routine physical examination.  The boy is going to a school for students with learning disabilities.  The patient was adopted, and his immunizations are up to date.  Review of the patient's medical records is notable for cytogenetic studies that showed a small gap near the tip of the long arm of the X chromosome, which is consistent with fragile X syndrome, an X-linked disorder. The defect is an unstable expansion of trinucleotide repeats (CGG) in the fragile X mental retardation 1 (FMR1) gene, located on the long arm of the X chromosome. He is not using any medications and vital signs are within normal levels. His blood chemistry analysis as bellow:
Blood Chemistry Value      Normal Range     Patient Value
Glucose                    90-120 mg/dl     95 mg/dl
BUN (Blood Urea Nitrogen)  7-24 mg/dl       10 mg/dl
Creatinine                 0.7-1.4 mg/dl    0.8 mg/dl
Calcium                    8.5-10.5 mg/dl   9 mg/dl
Sodium                     134-143 mEq/L    135 mEq/L
Potassium                  3.5-4.5 mEq/L    3.7 mEq/L
Chloride                   95-108 mEq/L     98 mEq/L
CO2                        20-30 mEq/L      25 mEq/L
Blood pH                   7.38-7.42        7. 39

Patient description (patient's own words): My husband and I brought our 15-year-old son to the clinic for his routine exam. My son is going to school for special needs students. We adopted him a few years ago. His vaccinations are up to date. He already passed some chromosome testing and they found that he has a fragile X syndrome. The doctor told us that it comes from repeats in the fragile X chromosome. My son is not using any medication and his blood pressure temperature and breathing were normal during the exam. He also did a blood test. The results came back and showed that his blood sugar urea creatinine calcium sodium potassium chloride CO2 and blood pH were all within the normal range.

Does the patient match the trial criteria? Entailment
Clinical trial: Study on Laparoscopic D2 Lymphadenectomy Plus Complete Mesogastrium Excision（D2+CME）for Advanced Gastric Cancer (NCT01978444)

Eligibility criteria:
Inclusion Criteria:

        Age from over 18 to under 75 years Primary gastric adenocarcinoma (papillary, tubular,
        mucinous, signet ring cell, or poorly differentiated) confirmed pathologically by
        endoscopic biopsy cT2-4a, N0-3, M0 at preoperative evaluation according to the AJCC Cancer
        Staging Manual Seventh Edition Expected curative resection through gastrectomy with D2
        lymphadenectomy Performance status of 0 or 1 on ECOG (Eastern Cooperative Oncology Group)
        scale ASA (American Society of Anesthesiology) score class I, II, or III Informed consent
        obtained from patients or their appointed agent

        Exclusion Criteria:

        Patients treated with neoadjuvant chemotherapy or radiation therapy; Patients with history
        of upper abdominal surgery; History with other severe comorbidities and cannot tolerate
        laparoscopic surgery, such as severe heart and lung diseases, heart function below clinical
        stage 2, pulmonary infection, moderate to severe COPD, chronic bronchitis, severe diabetes
        and / or renal insufficiency, severe hepatitis and / or function below the rank of CHILD B
        grade, and severe malnutrition, etc; Patients suffering from malignant diseases before the
        study or with other gastric malignant diseases, such as lymphoma and stromal tumors, etc.;
        Pregnant woman and woman during lactation; Patients with mental sickness; The patient
        compliance is bad or the researcher expect there will not be good patient compliance;
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment