araag2/NLI4PR huggingface dataset:
Clinical trial: A Trial of Booklet Based Self Management of Dizziness (NCT00732797)

Eligibility criteria:
Inclusion Criteria:

          -  Be 18 years or over

          -  Be registered with a participating GP

          -  Must have visited their GP for dizziness in the last 2 years

          -  Must complete the consent form, and baseline questionaire indicating they are still
             suffering from dizziness and that quick head movements make them dizzy.

        Exclusion Criteria:

          -  Non-Labyrinthe cause of dizziness identified by GP

          -  Medical contraindications from making normal head movements

          -  Serious co-morbidity

          -  Moved away from practice

          -  Recently deceased

          -  Non-English speakers, and unable to read/write in English.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient description (patient's own words): The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Does the patient match the trial criteria? Entailment
Clinical trial: Qudratus Lumborum Block Versus Unilateral Intrathecal Block for Inguinal Hernia Repair (NCT04805580)

Eligibility criteria:
Inclusion Criteria:

        - physical status ASA: I-II BMI >18kg/m2<30kg/m2 written informed consent from the patient
        scheduled for open unilateral inguinal hernia repair

        Exclusion Criteria:

          -  uncooperative patient

          -  Allergy to local anesthetic drugs

          -  patients on chronic alcohol, opioid, tranquilizer or sedative use

          -  Pregnant females.

          -  Psychological, mental disorders, or depression.

          -  Patients receiving anticoagulants therapy or suspected coagulopathy.

          -  Patients with infection or previous surgery at sit of anesthetic procedures.

          -  Patients with significant cardiovascular, respiratory, renal, hepatic, or metabolic
             disease
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Contradiction
Clinical trial: Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids (NCT01388764)

Eligibility criteria:
Inclusion Criteria:

          -  Confirmation of diagnosis of dystrophinopathy, documented by clinical exam and
             dystrophin DNA mutation analysis

          -  Ambulatory male subjects between the ages of 7-11 years

          -  Stable dosage of corticosteroids for 3 months prior to entry (Screening/Baseline Day
             0) and during treatment period

          -  Able to follow instructions and give assent

          -  Able to complete nonsedated MR

        Exclusion Criteria:

          -  Presence of metallic orthopedic hardware in the lower extremity that could affect
             MRI/MRS measurements

          -  Routine MRI exclusion criteria such as the presence of a pacemaker, cochlear implant,
             or cerebral aneurysm clip

          -  Subjects not capable of cooperating during MR examination

          -  Known hypersensitivity to L-arginine

          -  Exposure to another investigational agent, investigational supplements, growth hormone
             within 3 months prior to entry (Screening/Baseline Day 0) or during treatment period

          -  Subjects must not be taking L-arginine for at least 4 weeks prior to entry (Day 0)

          -  Subjects who are non-ambulatory or with daytime ventilatory dependence
Male
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.
Subject must be at most 11 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? Entailment
Clinical trial: Quantitative Liver Functions in Turner Syndrome With and Without Hormone Replacement Therapy (NCT00825617)

Eligibility criteria:
Inclusion Criteria:

          -  Turner syndrome by karyotype

        Exclusion Criteria:

          -  Thyroid abnormality

          -  Glucocorticoid treatment
Female
Accepts Healthy Volunteers



Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain (NCT01742897)

Eligibility criteria:
Inclusion Criteria:

          -  Chronic (lasting a long time) primary osteoarthritis knee pain, one or two side with
             stage II Kellgen-Lawrence, for more than 3 months with Visual Analogue Scale (VAS)
             more than 4

          -  Good knee deformity, no limit range of motion

          -  Participant who has signed the informed consent form

        Exclusion Criteria:

          -  Skin disease that prevents the use of the transdermal system or which could affect the
             absorption of fentanyl or local tolerability

          -  History or suspicion of alcohol or drug abuse within the past 5 years

          -  History of cardiac, nervous system or respiratory disease which in the investigator's
             judgment prevents participation in the study because of the potential for respiratory
             depression

          -  Confusion, reduced level of consciousness, or concomitant psychiatric disorder which,
             in the opinion of the investigator, could prevent participation in the trial

          -  Participants who do not understand or speak Thai
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia (NCT00108758)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of congenital haemophilia A or B with inhibitors development against FVIII
             or FIX, respectively

        Exclusion Criteria:

          -  Prophylactic administration of any haemostatic drug within 3 last months prior to
             entering the trial.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.


Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Isolation of the Spermatic Cord in Mesh Inguinal Hernia Repair (NCT01391455)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of a primary unilateral inguinal hernia

        Exclusion Criteria:

          -  Medically unfit for surgical repair
Male
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus (NCT03293368)

Eligibility criteria:
Inclusion Criteria:

          -  Patients presenting with a clinical picture that assumes the diagnosis of erosive oral
             lichen planus (bilateral, more or less symmetrical erosive lesions with lacelike
             network of slightly raised gray white lesions (reticular pattern), and a histological
             findings that confirms the diagnosis (liquefaction degeneration of the basal cell
             layer with irregular-saw teeth like rete pegs.

        Exclusion Criteria:

          -  Systemic disorders such as hematological diseases, severe cardiovascular diseases,
             treatment with any drugs that could cause Lichenoid reaction.

          -  Pregnancy or active breastfeeding

          -  Patients who had lesion/lesions with dysplasia

          -  Patients who received topical treatment for Oral Lichen planus in the last 2 weeks
             (Lee et al., 2013) or systemic treatment for OLP in the past 3 months.

          -  Platelet count < 150,000/mm3; Hgb < 11 g/dl.

          -  Immunosuppressed patients

          -  Patients receiving therapy with anticoagulants and use of non-steroidal
             anti-inflammatory drugs in the 5 days before taking the blood sample.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Entailment
Clinical trial: Salivary Catecholamines in Aphthous Stomatitis (Canker Sores) (NCT00556686)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 or older, both genders

          -  History of recurrent aphthous ulcers with 4 or more episodes per year

        Exclusion Criteria:

          -  History of salivary gland disease including Sjogren's disease, parotitis, and
             sialolithiasis

          -  History of benign or malignant salivary gland tumor

          -  History of celiac disease, ulcerative colitis or Crohn's disease

          -  Patients on medications that affect salivary flow such as anti-depressants and
             anti-cholinergic medications
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients (NCT00444275)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects who seek medical advice in primary care for symptoms thought to be GERD
             related (GERD is a condition which develops when the reflux of stomach content causes
             troublesome symptoms and / or complications).

        Exclusion Criteria:

          -  Subjects with any clinical GERD treatment (PPI, H2-receptor antagonists) within the
             last 3 months prior to Visit 1.

          -  A history of severe esophagitis or known other complications, with alarm symptoms
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction