araag2/NLI4PR huggingface dataset:
Clinical trial: Effect of Smoking Exposure on Smoking Relapse Following Brief Abstinence - 2 (NCT00136838)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of nicotine dependence with psychological dependence

          -  Smokes at least 15 cigarettes per day for the three months prior to enrollment

          -  Currently not seeking treatment for nicotine dependence

          -  Medically healthy, on the basis of physical examination and medical history, vital
             signs, EKG, and laboratory tests

          -  Females must use an effective method of contraception for the duration of the study

        Exclusion Criteria:

          -  Diagnosis of abuse or dependence on alcohol or drugs other than nicotine

          -  Current Axis I diagnosis or current treatment with psychotropic medications within the
             3 months prior to enrollment

          -  History of schizophrenia or other psychotic disorders, bipolar disorder, or anxiety
             disorders

          -  Currently seeking treatment for nicotine disorders

          -  On parole or probation

          -  History of seizures or head trauma with loss of consciousness, brain contusion, or
             fracture

          -  History of significant recent violent behavior

          -  Blood pressure greater than 150/90

          -  History of eating disorders

          -  Pregnant
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: Ultrasound and Videofluoroscopy for Diagnosing Swallowing Disorders (NCT00001220)

Eligibility criteria:
INCLUSION CRITERIA:

        Any Clinical Center inpatients and outpatients with known or suspected dysphagia on any
        other NIH institute protocol can be included for study as well as patients who are admitted
        specifically for this protocol.

        Those patients at risk for oropharyngeal dysfunction will be screened initially by
        completing a self-assessment swallowing questionnaire, and by an interview with staff
        and/or family members. Patients who demonstrate appropriate signs and symptoms of dysphagia
        and oral motor impairment on the screening assessment will be considered for the protocol:

        Difficulty swallowing food or pills.

        Changed swallowing ability.

        Coughing or choking when eating.

        Shortness of breath during swallowing.

        Food backing up into the mouth or nasal passage.

        Fever or voice changes after swallowing.

        Pain when swallowing.

        Unexplained loss of weight.

        EXCLUSION CRITERIA:

        Patients who are severely demented or severely compromised will be excluded if they do not
        have sufficient cognitive ability to follow directions.

        Patients who are non-ambulatory will be excluded if they can not be braced or supported
        within the fluoroscopy unit.

        Highly agitated individuals will also be excluded if they are unable to remain confined in
        the equipment.

        Infants and children under age 3 will be excluded due to radiation risk on the developing
        visual system.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women (NCT00043719)

Eligibility criteria:
Inclusion Criteria:

          -  Postmenopausal for a minimum of 13 months

          -  Lumbar spine T-score of 0 to -2.5 (0 to -2.0 if over 60 years old) by Dual Energy
             X-ray Absorptiometry (DEXA) (i.e., evidence of normal bone mass or osteopenia)

          -  Body Mass Index (BMI) between 18 and 32

          -  Planning to live in the greater New Brunswick, NJ, area for at least 3 years

        Exclusion Criteria:

          -  Radiographically or DEXA-morphometrically proven vertebral or hip fracture

          -  Conditions requiring routine use of sublingual, transdermal, or oral nitrates

          -  Significant postmenopausal symptoms that require estrogen therapy

          -  Metabolic bone diseases other than postmenopausal bone loss (e.g., active
             hyperthyroidism, hyperparathyroidism, Paget's disease of bone, etc.)

          -  Insulin-dependent diabetes mellitus

          -  Significant migraine headaches

          -  History of renal calculi

          -  Cancer within 5 years prior to study entry

          -  Any condition causing an anticipated life expectancy of less than 3 years

          -  Failure to maintain 75% to 125% compliance with open-label calcium with vitamin D
             regimen during the screening period
Female
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Osteoporosis Coordinator for Low Volume Community Hospitals (NCT00511693)

Eligibility criteria:
Inclusion Criteria:

          1. Cluster site (hospital) level: Hospitals with no dedicated osteoporosis coordinator
             that treat more than 60 patients/year in their Emergency Department and who have a
             Telehealth studio.

          2. Patient level: Patients 40 years old and over (men and women) presenting with a low
             trauma fracture of the hip, forearm and wrist, rib(s), sternum, thoracic and lumbar
             spine, shoulder and upper arm, pelvis, lower leg and ankle. Subjects without previous
             medication as well as subjects on osteoporosis medication and presenting with a
             fracture will be included.

        Exclusion Criteria:

          1. Hospitals that have an Osteoporosis Strategy fracture clinic coordinator

          2. Fractures associated with major trauma; fractures due to malignancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Giant Cell Arteritis and Differential Diagnoses Associated With Positive Temporal Artery Biopsy (NCT04554290)

Eligibility criteria:
Inclusion Criteria:

          -  positive artery biopsy between january 1st 2000 and july 25th 2019

        Exclusion Criteria:

          -  orther vascular biopsy than temporal artery biospy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient description (patient's own words): I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Does the patient match the trial criteria? Entailment
Clinical trial: Randomized Safety, Tolerability and Pilot Efficacy of AN-1792 in Alzheimer's Disease (NCT00021723)

Eligibility criteria:
Mild to moderate Alzheimer's disease. Ability to cooperate with MRI scanning and
        neuropsychological testing. Live at home or in the community and a caregiver capable of
        accompanying the patient on all clinic visits and visiting the patient at least 5 times per
        week.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? Entailment
Clinical trial: Secondary Fracture Prevention in Patients Who Suffered From Osteoporotic Fracture (NCT02223572)

Eligibility criteria:
Inclusion Criteria:

          -  Adults over 18 years old

          -  Patients diagnosed with low energy osteoporotic hip fracture, and was treated under
             surgery.

        Exclusion Criteria:

          -  Patients not diagnosed with osteoporosis.

          -  Patients diagnosed with high energy osteoporotic hip fracture.

          -  Patients that suffered from Multiple Trauma.

          -  Patients diagnosed with Metabolic diseases or Genetic diseases.

          -  Pregnant women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Validation, Reliability and Pilot Test of the Personalized Exercise Questionnaire (PEQ) (NCT03125590)

Eligibility criteria:
Inclusion Criteria:

          1. The participant is able and willing to provide informed consent

          2. The participant is male or female, 18+

          3. The participant has received a diagnosis, from a physician, of primary osteopenia or
             osteoporosis (T < - 1.0)

          4. The participant can read and write English

        Exclusion Criteria:

          1. The participant has been diagnosed with secondary osteopenia or osteoporosis

          2. The participant has a history of smoking, alcoholism, gastrointestinal disease,
             hypercalciuria and/or steroid use.

          3. The participant is diagnosed with a reading disability or dyslexia

          4. The participant has a cognitive impairment of some severity as to adversely affect the
             validity of the data
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin (NCT02033876)

Eligibility criteria:
Overweight or Obese subjects with BMI> 25 Kg/m2 with Type 2 Diabetes mellitus on Metformin,
        receiving standard of care for Type 2 DM. Otherwise individuals who are not currently on
        treatment for cardiac, pulmonary, gastrointestinal, hepatic, renal, hematological,
        neurological, endocrine (other than T2DM) and unstable psychiatric disease.

        Men or women. Women of childbearing potential will have a negative pregnancy test before
        initiation of medication.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Entailment