araag2/NLI4PR huggingface dataset:
Clinical trial: High Intensity Strength Training & Bone Mineral Density in Young Women (NCT01482130)

Eligibility criteria:
Inclusion Criteria:

          -  Participants include young and healthy women between the ages of 18-30, who have not
             engaged in strength training for the last 6 months.

        Exclusion Criteria:

          -  Subjects will be excluded from the study if they have any condition that preclude them
             from taking part in the exercise testing procedures or the 24 week exercise program or
             if they fail to obtain the required amount of training sessions.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Management of Persistent Epistaxis Using Floseal Hemostatic Matrix (NCT02488135)

Eligibility criteria:
Inclusion Criteria:

          -  All patients age 18+ presenting with epistaxis that requires an ENT consult that had a
             first attempt at treatment by an emergency physician.

        Exclusion Criteria:

          -  Patients will be excluded based on the presence of a hypo-coagulable state. Including
             patients actively taking anti-coagulant medications or other patients with either
             acquired or hereditary bleeding disorders.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Yoga as an Intervention for Women With Knee Osteoarthritis (NCT02146105)

Eligibility criteria:
Inclusion Criteria:

          -  Female - 50 years of age or older

          -  Knee pain on most days of the week

          -  Less than 30 minutes of morning stiffness

          -  Bony enlargement

          -  Bony tenderness to palpation

          -  Signs of inflammation

          -  Able to safely climb 2 flights of stairs without aid

          -  Visited a family physician within the last 12 months

        Exclusion Criteria:

          -  Any other forms of arthritis

          -  Osteoporosis

          -  History of patellofemoral symptoms

          -  Active non-arthritic knee disease

          -  Knee surgery

          -  Use of cane or walking aid

          -  Unstable heart condition

          -  Neurological conditions

          -  Skin allergy to medical tape

          -  Hip or ankle injuries in past 3 months

          -  Any injuries that would prohibit participation in yoga

          -  Ipsilateral hip or ankle conditions

          -  Currently receiving cancer treatment

          -  Currently pregnant
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Determinants of SARS-COV2 (COVID-19) Persistence After Convalescence (NCT04448145)

Eligibility criteria:
Inclusion Criteria:

          -  Laboratory confirmed SARS-CoV-2 using currently available laboratory testing
             techniques (e.g.,RT-PCR, Immunoglobulin M (IgM) /IgG) or clinical history compatible
             with a COVID-19 like illness(fever, cough, shortness of breath).

          -  Negative participants with no known prior COVID-19 diagnosis or COVID vaccine

          -  At least 7 years of age

          -  Participants are eligible to provide semen and breast milk samples if they are 18
             years of age or older

        Exclusion Criteria:

          -  Age <7

          -  Intercurrent conditions that in the opinion of the investigator would confound the
             findings of the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Hemophilia Inhibitor Previously Untreated Patient Study (NCT01652027)

Eligibility criteria:
Inclusion Criteria:

          -  Severe hemophilia A with FVIII activity < 1% normal

          -  Weight > 3.5 kg at the time of baseline study evaluation

          -  Informed consent, approved by appropriate Institutional Review Board/Independent
             Ethics Committee, has been administered, signed, and dated

        Exclusion Criteria:

          -  Prior exposure to clotting factor concentrates or blood products

          -  Other chronic disease

          -  Currently participating in another investigational drug study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: ICSI Versus Conventional IVF in Non-male Factor Couples (NCT03428919)

Eligibility criteria:
Inclusion Criteria:

          -  Having ≤ 2 IVF/ICSI cycles

          -  Total sperm count and motility are normal (WHO, 2010)

          -  Antagonist protocol

          -  Agree to have ≤ 2 embryos transferred

          -  Not participating in another IVF study at the same time

        Exclusion Criteria:

          -  In-vitro maturation (IVM) cycles

          -  Using frozen semen

          -  Poor fertilization in previous cycle (≤ 25%)
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Health and Cancer Issues in the South Asian Community (NCT00479830)

Eligibility criteria:
Inclusion Criteria:

          1. Self identified South Asian (Asian Indian, Bangladeshi, Pakistani, Sri Lankan)
             residents of Harris, Fort Bend, Brazoria and Galveston counties.

          2. 18 years of age or older

          3. Those who speak the languages (including English) that had been identified as most
             frequently used in Houston's South Asian community by the Community Advisory
             Committee.

        Exclusion Criteria:

          1. None

          2. Sri Lankans who participated in Protocol 2006-1047.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Lung Disease Collection (Qatar): Evaluation of the Lungs of Individuals With Lung Disease (NCT00504738)

Eligibility criteria:
Inclusion Criteria:

        Inclusion/Exclusion criteria for Part A

          -  Must provide informed consent

          -  Males and females, age 18 years and older

          -  Evidence of lung disease by at least one of the following:

               1. symptoms consistent with pulmonary disease;

               2. chest X-rays and/or chest CT consistent with lung disease;

               3. pulmonary function tests consistent with lung disease;

               4. lung biopsy consistent with lung disease;

               5. family history of lung disease;

               6. diseases of organs with known association with lung disease; and

               7. individuals suspected of having lung disease based on history and/or physical
                  examination

          -  Undergoing fiberoptic bronchoscopy as dictated by their standard clinical care

        Exclusion Criteria:

          -  Patient refuses consent.

        Patients enrolled in Part A of the protocol will not undergo screening procedures/tests.
        These patients are undergoing a fiberoptic bronchoscopy as dictated by their standard
        clinical care and additional samples will be taken for research purposes.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Can 3D Laparoscopy Improve Surgical Performances in Surgeons in Training? (NCT04209036)

Eligibility criteria:
Inclusion Criteria:

          -  Patients suffering from benign uterine pathology (uterine fibromatosis, abnormal blood
             loss, complex hyperplasia with atypia, uterine prolapse) with indication for total
             uterine hysterectomy

          -  Uterine size </= than 15 cm

          -  American Society of Anesthesiologists (ASA) class < 3

          -  Patient's informed consent

          -  No actual pregnancies or pelvic inflammatory disease

          -  No previous major abdominal surgical procedures

        Exclusion Criteria:

          -  Suspected neoplastic pathology

          -  Patients not eligible for surgery
Female




Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding Disorders (NCT00904709)

Eligibility criteria:
Inclusion Criteria:Clinical diagnosis of Menorrhagia

          -  Must be able to swallow tablets

        Exclusion Criteria:

          -  Endometrial abnormality

          -  Pelvic infection

          -  Pregnancy

          -  Breast Feeding

          -  Requirement for birth control

          -  Known intolerance/lack of effect of tranexamic acid
Female
Accepts Healthy Volunteers
Subject must be at least 15 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment