araag2/NLI4PR huggingface dataset:
Clinical trial: Virtual Reality for Osteoarthritis Knee Pain Pilot (NCT01899508)

Eligibility criteria:
Inclusion Criteria:

          -  Must be 18-85 years old

          -  Have a clinical diagnosis of OA of the knee

          -  Be able to read and write English

        Exclusion Criteria:

          -  Can't have rheumatoid arthritis, fibromyalgia, or other chronic pain condition.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: 3D HD Versus 2D HD in Laparoscopic Inguinal Hernia Repair: a Randomized Controlled Trial (NCT02396940)

Eligibility criteria:
Inclusion Criteria:

          -  Patients scheduled for elective inguinal hernia repair (out-patient treatment)

        Exclusion Criteria:

          -  Previous lower abdominal surgery

          -  ASA-score 3 or above
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: MOTHIF II : THERAPEUTIC MANAGEMENT AND USE OF CLOTTING FACTORS IN HEMOPHILIA A & B IN FRANCE II (NCT03596814)

Eligibility criteria:
Inclusion Criteria:

          -  All patients hemophiliac A or B, with or without inhibitors, included in the Nhemo (7
             centres) and the Behrlingo database, treated with factor 8 or factor 9 products or
             by-passing agents

          -  All Hemophilia A or B patients of any severity without inhibitors, included in the
             NHEMO database and the BEHRLINGO database, without any treatment by clotting factors

          -  All Hemophilia A or B patients having given consent to be included in the study (2
             times 12 months), during their usual follow-up (consultation…). For the other
             patients, a derogation from the obligation to inform the patients will be made to the
             CNIL.

        Exclusion Criteria:

          -  patients under guardianship
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Entailment
Clinical trial: MCE Direct Visualization of Drug Behavior in Upper-gastrointestinal Tract (NCT04327869)

Eligibility criteria:
Inclusion Criteria:

          -  With or without gastrointestinal complaints

          -  Scheduled to undergo a capsule endoscopy for both stomach and small bowel

          -  Signed the informed consents before joining this study

        Exclusion Criteria:

          -  Suspected or known gastrointestinal stenosis

          -  Obstruction or other known risk factors for capsule retention

          -  Pregnancy or suspected pregnancy

          -  Pacemakers or electromedical devices implanted

          -  Any other contraindications determined by endoscopists
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: The Effects of Testosterone on Prostate Tissue (ACYP-1) (NCT00161486)

Eligibility criteria:
Inclusion Criteria:

          -  Males between 35 and 55, normal serum testosterone levels, normal gonadal function

        Exclusion Criteria:

          -  History of prostate cancer, PSA>2.0, AUA BPH symptom score >10, History of
             testosterone or anabolic steroid use, chronic medical illness or prostate disease,
             active serious infection or immunosuppression, history of a bleeding disorder or need
             for anticoagulation, abnormal digital rectal exam, abnormal prostate ultrasound, first
             degree relative with history of prostate cancer
Male
Accepts Healthy Volunteers
Subject must be at least 35 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage (NCT02686840)

Eligibility criteria:
Inclusion Criteria:

          -  All women above 18 years of age

          -  Less than 12 weeks of gestation.

          -  Pregnancy is confirmed by pregnancy test or ultrasound scan.

          -  missed abortion

          -  Normal general and gynecological examination.

          -  The size of the uterus on pelvic examination was compatible with the estimated
             duration of pregnancy

        Exclusion Criteria:

          -  Hemodynamically unstable.

          -  Suspected sepsis with temperature 38 °C.

          -  Concurrent medical illness e.g. hematological, cardiovascular, thromboembolism,
             respiratory illnesses, recent liver disease or pruritus of pregnancy.

          -  Presence of intrauterine contraceptive device (IUCD).

          -  Suspect or proven ectopic pregnancy.

          -  Failed medical or surgical evacuation before presentation.

          -  Known allergy to misoprostol.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Individualized Comprehensive Rehabilitation Program in Chronic Knee Osteoarthritis (NCT04138784)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of primary symptomatic KOA according to the criteria of the American College
             of Rheumatology

          -  Women aged older than 65 years

          -  Pain predominantly over the last 3 months

          -  Kellgren and Lawrence score ≥2.

        Exclusion Criteria:

          -  Ankle, hip or foot severe disorders

          -  Chronic back pain

          -  Alzheimer's disease, Parkinson's disease, motor neuron disorders.

          -  Diabetes mellitus

          -  Cardiac or respiratory insufficiency

          -  Inability to understand the procedure
Female
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: Efficacy and Safety of a a Biofunctional Textile in the Management of Atopic Dermatitis (NCT01597817)

Eligibility criteria:
Inclusion Criteria:

          -  clinical diagnosis of Atopic Dermatitis

          -  older than 12 years old

        Exclusion Criteria:

          -  other specific forms of eczema such as contact eczema, seborrheic eczema, nummular
             eczema, occupational dermatitis, hand eczema

          -  systemic diseases that can be accompanied by immunological skin abnormalities as
             psoriasis;

          -  clinically significant chronic infectious disease(s) (eg, HIV, hepatitis B or C);

          -  breastfeeding,pregnant/intending to become pregnant during study;

          -  participation in any other clinical study;

          -  part of the staff personnel involved with the study;

          -  family member of investigational/study staff.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.


Patient description (medical language): A 2-year-old boy is brought to the office by his parents due to a rash that started 1 week ago.  A similar red, itchy rash on the cheeks, trunk, and arms has occurred intermittently since infancy.  The patient has had a few upper respiratory infections but no major illnesses.  Vaccinations are up to date, and he takes no medications. He is on a balanced diet, and he is healthy in appearance.  Vital signs and milestone examination are within normal limits.  Similar findings are observed on the cheeks and proximal upper extremities.  The diaper area is clear, and no mucosal lesions are present.

Patient description (patient's own words): I just brought my two-year-old son to the doctor's office because he had a rash for like one week. His rash was on the cheeks, the trunk, and his arms. He already had this before, and it keeps coming back from time to time to time. In the past, he had some respiratory infections but he has never been this sick. His vaccinations are up to date, and he doesn't take any medication. He's healthy with a nice diet. The doctor told me his vitals and milestone examinations were normal. The doctor also said there was a rash around the cheek and the upper part of his arms. The diaper area is okay, and there are no lesions.

Does the patient match the trial criteria? Contradiction
Clinical trial: Test to Determine the Effectiveness of Moisturizing Balm Used on Babies With Dry, Itchy Skin (NCT02404493)

Eligibility criteria:
Inclusion Criteria:

          1. Able to comprehend and follow the requirements of the study (including availability on
             scheduled visit dates)

          2. Male or female of any race or ethnicity, 6 months to 47 months of age;

          3. Diagnosed as having eczema

          4. Willing to stop use of all non-assigned moisturizers and/or creams for the entire
             duration of the study

          5. Child must have bedtime/sleep issues due to their dry, itchy skin

        Exclusion Criteria:

          1. Use of a therapeutic (over-the-counter or prescription) body wash that contains an
             active ingredient for eczema

          2. Participation in any clinical study within 30 days of Visit 1

          3. Active infection of any type at the start of the study

          4. Diagnosed as having severe eczema

          5. Atopic Dermatitis requiring systemic, super-potent (Class I) or potent (Class II or
             III) topical corticosteroids

          6. Child wakes up 3 or more times during the night

          7. Child is awake more than 60 minutes during the night

          8. Child sleeps for less than a total of 9 hours (during the day or night)

          9. Child requires greater than 2.0 mg per day of inhaled or intranasal corticosteroids
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 47 Months

Patient description (medical language): A 2-year-old boy is brought to the office by his parents due to a rash that started 1 week ago.  A similar red, itchy rash on the cheeks, trunk, and arms has occurred intermittently since infancy.  The patient has had a few upper respiratory infections but no major illnesses.  Vaccinations are up to date, and he takes no medications. He is on a balanced diet, and he is healthy in appearance.  Vital signs and milestone examination are within normal limits.  Similar findings are observed on the cheeks and proximal upper extremities.  The diaper area is clear, and no mucosal lesions are present.

Patient description (patient's own words): I just brought my two-year-old son to the doctor's office because he had a rash for like one week. His rash was on the cheeks, the trunk, and his arms. He already had this before, and it keeps coming back from time to time to time. In the past, he had some respiratory infections but he has never been this sick. His vaccinations are up to date, and he doesn't take any medication. He's healthy with a nice diet. The doctor told me his vitals and milestone examinations were normal. The doctor also said there was a rash around the cheek and the upper part of his arms. The diaper area is okay, and there are no lesions.

Does the patient match the trial criteria? Entailment
Clinical trial: Three-dimensional Kinematic Motion Analysis of Finger and Wrist During Daily Activities (NCT02890862)

Eligibility criteria:
Inclusion Criteria:

          -  Volunteers of 20 healthy, right dominant hands

          -  10 patients with tendon pathologies

          -  10 patients with Dupuytren disease

          -  10 patients with osteoarthritis of the wrist

          -  Patients older than 18 years

          -  Patient willing and able to give written informed consent to participate in the study

        Exclusion Criteria:

          -  Inflammatory disease (e.g. rheumatoid arthritis)

          -  Pregnant women

          -  German language barrier to complete the questionnaires

          -  Any disease process that would preclude accurate evaluation (e.g. neuromuscular,
             psychiatric or metabolic disorder)

          -  Legal incompetence

          -  Participation in any other medical device or medicinal product study within the
             previous months that could influence the results of the present study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction