araag2/NLI4PR huggingface dataset:
Clinical trial: Light and the Effect on Metabolic Syndrome and Alzheimer's Disease (NCT03777722)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of mild to moderate Alzheimer's disease or related dementia,

          -  type 2 diabetes

          -  sleep disturbance as determined by a score ≥ 5 on the PSQI

        Exclusion Criteria:

          -  insulin-dependent diabetes,

          -  urinary incontinence

          -  obstructing cataracts

          -  macular degeneration

          -  blindness

          -  severe sleep apnea or

          -  restless leg syndrome (RLS)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.


Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? Entailment
Clinical trial: Movement Visualization in Patients With Hemophilic Arthropathy (NCT04237766)

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed with hemophilia A and B

          -  Medical diagnosis of hemophilic arthropathy

          -  Chronic joint pain

          -  Over 18 years

          -  On prophylactic treatment or on demand with FVIII / FIX concentrates

        Exclusion Criteria:

          -  Patients with neurological or cognitive disorders that impede the understanding of the
             questionnaires

          -  Painless patients

          -  Amputee, epileptic or seriously impaired vision patients

          -  Patients receiving physiotherapy treatment at the time of the study

          -  Patients who have not signed the informed consent document.
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging (NCT03050957)

Eligibility criteria:
Inclusion Criteria:

          -  patients with suspicion of OD associated with aging (>70 years), neurodegenerative
             diseases or stroke.

        Exclusion Criteria:

          -  Patients with suspicion that they will not be able to compliment the protocol,
             patients participating or have participated in a clinical study the last 4 weeks and
             patients with alcoholic or drugs dependence
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 70 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Contradiction
Clinical trial: Abdominal Wall Function and Quality of Life and Before and After Incisional Hernia Repair (NCT02320071)

Eligibility criteria:
Inclusion Criteria:

          -  Elective laparoscopic repair for one or more incisional hernias in the midline (at
             least 5 cm caudal to the xiphoid process and at least 5 cm cranial to the pubic bone),
             using a synthetic mesh

          -  Horizontal fascial defect between 3 and 8 cm

          -  Age between 25 and 75 years

          -  American Association of Anesthesiologist score between I and III

          -  Body mass index < 33 kg/m^2

        Exclusion Criteria:

          -  Severe musculoskeletal, neurologic or cardiopulmonary disease preventing the patient
             from climbing stairs or shopping for groceries

          -  Existing stoma

          -  Postoperative complications requiring intervention
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease. (NCT01601379)

Eligibility criteria:
Inclusion Criteria:

          -  Patient has an established diagnosis of GERD according to the investigator, or an
             occurrence of at least 1 typical GERD symptom (i.e., heartburn or regurgitation) at
             least once a week during the last 3 months.

          -  Patient has presented at least 1 typical GERD symptom (i.e., heartburn or
             regurgitation) in the week preceding the study visit.

        Exclusion Criteria:

          -  Exclusively atypical digestive or non-digestive symptoms (e.g., epigastralgia,
             respiratory disturbances, thoracic manifestations, etc.)

          -  Current or recent (less than 1 year) history of gastric or duodenal ulcer

          -  History of surgery of the upper digestive tract

          -  Tumor of the superior digestive tract or ENT system;

          -  Pregnant or breastfeeding woman
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Magnetic Anchoring Guided Endoscopic Submucosal Dissection for Early Gastric Caner (NCT04327050)

Eligibility criteria:
Inclusion Criteria:

          -  Patients are diagnosed as of gastric cancer by a preliminary endoscopy or biopsy
             sampling

        Exclusion Criteria:

          -  Patients with a cardiac pacemaker or severe cardiac and/or pulmonary diseases

          -  Patients without informed consent

          -  Patients with other malignant tumors
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Oral Glutamine on Muscle Mass and Function in Duchenne Muscular Dystrophy (NCT00296621)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of Duchenne muscular dystrophy

          -  Able to walk >170 m

          -  Absence of hepatic insufficiency

          -  Absence of renal insufficiency

        Exclusion Criteria:

          -  Dependent upon wheelchair

          -  Body weight >60kg

          -  Liver failure

          -  Kidney failure

          -  Surgery scheduled during the year following the first visit
Male
No healthy subjects accepted to join the trial.



Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? Entailment
Clinical trial: Detection of Helicobacter Pylori Infection by High Resolution Endoscopy (NCT01434992)

Eligibility criteria:
Inclusion Criteria:

          -  Patients who underwent upper endoscopy

        Exclusion Criteria:

          -  Age < 20 or > 70

          -  Severe systemic disease or advanced chronic liver disease

          -  Medication history of NSAID, PPI, H2 blockers or antibiotics

          -  History of H. pylori eradication therapy

          -  History of gastric surgery

          -  Recent history of upper GI bleeding

          -  Gastric or duodenal ulcer (including old scar change) during endoscopy

          -  Anemia (Hemoglobin level < 10mg/dL)

          -  Pangastritis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Evaluation of Clinical Characteristics and Outcome of COVID19 Pneumonia in Assiut University Hospital (NCT04481360)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with COVID 19 PCR positive

        Exclusion Criteria:

          -  Patients less than 18 years of age .
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: A RCT on the Effect of Endometrial Injury on Improving Ongoing Pregnancy Rate in Subfertile Women Undergoing FET Cycles (NCT02197832)

Eligibility criteria:
Inclusion Criteria:

          -  Undergoing FET treatment cycles

          -  Normal uterine cavity as shown on transvaginal scanning or saline sonogram done at
             baseline

          -  endometrial thickness >=8mm during the stimulated IVF cycle and FET cycle

        Exclusion Criteria:

          -  Pregnancy in previous IVF or FET cycles

          -  Presence of hydrosalpinx not surgically corrected prior to FET

          -  Presence of endometrial polyp or fibroid distorting uterine cavity

          -  IVF cycles carried out for preimplantation genetic diagnosis

          -  Arrange for blastocyst transfer

          -  Use of donor oocytes
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Phase 2 Study of URC102 to Assess the Efficacy and Safety in Gout Patients (NCT02290210)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosed with gout

        Exclusion Criteria:

          -  Participated in other clinical study within 12 weeks prior to enrollment, and received
             an investigational product (including placebo)
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Entailment
Clinical trial: Registry for Integrative Medicine Interventions Effectiveness (NCT01754038)

Eligibility criteria:
Inclusion Criteria:

          -  Be seen as a clinical patient in one of the participating Integrative Medicine (IM)
             clinics and willing to participate in the Registry

          -  Be 18 years of age or older

          -  Have access to a computer with internet connection and a valid email address

          -  Be willing to be contacted in the future by study investigators

        Exclusion Criteria:

          -  Not being seen by a provider for clinical purposes, but only involved in an education
             program or one-time activity
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment