araag2/NLI4PR huggingface dataset:
Clinical trial: Phase II Study for Robot Assisted Distal Gastrectomy (NCT01504997)

Eligibility criteria:
Inclusion Criteria:

          1. Biopsy specimen from the primary lesion shows adenocarcinoma

          2. Diagnosed as Stage IA early gastric cancer according to the preoperative
             esophagogastroduodenoscopy and computer tomography

          3. Endoscopic submucosal dissection is not indicated

          4. Tumor was located within lower two thirds of stomach

          5. Not having duodenal invasion

          6. Eastern clinical oncology group performance status is 0 or 1

          7. Body mass index is lower than 30

          8. No prior laparotomy

          9. No prior chemotherapy or radiation including those for other cancers

         10. Fulfil all following conditions WBC > 3,000/mm3 Plt > 100,000/mm3 AST < 100 IU/L ALT <
             100IU/L T.Bil < 2.0 g/dl Cre < 1.5mg/dl

        Exclusion Criteria:

          1. Having other active cancers

          2. Possibly pregnant, or breast feeding woman

          3. with psychiatric disorder

          4. Receiving steroids

          5. With Acute myocardial infarction in 6 months or with unstable angina

          6. With uncontrolled hypertension

          7. With uncontrolled diabetes mellitus

          8. With pulmonary disease which require continuous oxygen therapy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Ultrasound-guided Inguinal Field Block (Genitofemoral, Iliohypogastric and Ilioinguinal Nerve Block) for Inguinal Hernia Surgery (NCT01521481)

Eligibility criteria:
Inclusion Criteria:

          -  BMI (Body mass index) < 30

          -  Non severe liver, renal or cardiac disease

          -  No allergy or contraindications to any of the study drugs

          -  American Hernia Society Score type I-II-IV-V hernia

          -  No pain or chronic analgesic administration in the preoperative period

          -  No previous surgery of the inguinal region

          -  Normal coagulation parameters and platelet count (> 100.000).

          -  Dicumarol and aspirin suspension for > 7 days

          -  Correctly administrated premedication

          -  No systemic infections

          -  No contraindications to subarachnoid anesthesia

        Exclusion Criteria:

          -  BMI (Body mass index) > 30

          -  Severe liver, renal or cardiac disease

          -  Allergy or contraindications to any of the study drugs

          -  American Hernia Society Score type III-VI-VII-0 hernia

          -  Pain or chronic analgesic administration in the preoperative period

          -  Previous surgery of the inguinal region

          -  Anormal coagulation parameters and platelet count (< 100.000).

          -  No dicumarol and aspirin suspension for > 7 days

          -  Incorrectly administrated premedication

          -  Systemic infections

          -  Contraindications to subarachnoid anesthesia
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Value of Rapid on Site Evaluation During EBUS-guided TBNA in the Diagnosis of Mediastinal Lesions (NCT02690610)

Eligibility criteria:
Inclusion Criteria:

          -  Hilar/mediastinal lymph nodes with a short axis more than 1 cm on thoracic CT scan
             and/or PET-CT suspicious for malignancy with or without known lung malignancy.

          -  Hilar and/or mediastinal lymph nodes positive on PET/CT scan without regarding the
             diameter suspicious for malignancy.

          -  Recurrence or restaging of NSCLC after chemotherapy or radiation.

          -  Diagnosis of lung cancer when there is no endobronchial lesion.

          -  Diagnosis of both benign (especially tuberculosis and sarcoidosis) and malignant
             mediastinal lesions (eg. thymoma).

        Exclusion Criteria:

          -  Cardiovascular instability.

          -  Lack of patient cooperation, e.g. intractable cough, inability to remain motionless or
             altered consciousness.

          -  Bleeding diathesis (activated partial thromboplastin time (APTT) ratio or
             international normalized ratio (INR) <1.3 or platelet count of <50000 per mm3).

          -  Respiratory failure and patient on mechanical ventilation.

          -  Severe chronic obstructive pulmonary disease (COPD) (FEV1<1 liter or <35% predicted).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of FYU-981 in Hyperuricemia With or Without Gout (NCT02344862)

Eligibility criteria:
Inclusion Criteria:

          -  Hyperuricemic or gout patients

          -  Serum urate level:

        >= 7.0mg/dL in patients with history of gout, or >= 8.0mg/dL in patients with hypertension,
        diabetes or metabolic syndrome, or >= 9.0mg/dL

        Exclusion Criteria:

          -  Gouty arthritis within two weeks before start of study treatment

          -  Secondary hyperuricemia

          -  HbA1c: >= 8.4%

          -  Uric acid-overproduction type in the classification of hyperuricemia

          -  History of, clinically significant cardiac, hematologic and hepatic disease

          -  Kidney calculi or clinically significant urinary calculi

          -  eGFR: < 60mL/min/1.73m^2

          -  Systolic blood pressure: >= 180 mmHg

          -  Diastolic blood pressure: >= 110 mmHg
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 64 Years

Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Fimasartan and Rosuvastatin for Hypertension and Dyslipidemia Control (NCT02913794)

Eligibility criteria:
Inclusion Criteria:

          -  Hypertension patients who are taking an anti-hypertensive agent, including Fimasartan
             at least 12 weeks or more.

          -  Dyslipidemia patients who are taking dyslipidemia drug, including Rosuvastatin at
             least 12 weeks or more

          -  Patients who has blood pressure and lipid levels (Total cholesterol, LDL-C, HDL-C,
             non-HDL-C, * TG) checks 2 weeks before registration

        Exclusion Criteria:

          -  Patients being hospitalized

          -  Patients who stop taking Fimasartan or Rosuvastatin within 12 weeks 14 or more
             consecutive days

          -  Patients who have more than 400mg/dl triglyceride(TG) at the registration time
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Electronic Cigarette Use on Cough Reflex Sensitivity (NCT02203162)

Eligibility criteria:
Inclusion Criteria:

          -  healthy adults (age18 years and above)

          -  nonsmokers

        Exclusion Criteria:

          -  previous smoker

          -  asthma/other respiratory illness

          -  acute viral upper respiratory tract infection (common cold) in previous 4 weeks
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: DECT Study in Allopurinol-Treated Gout Patients (NCT02393560)

Eligibility criteria:
Inclusion Criteria:

          -  Subject is able to understand the study procedures, the risks involved and willing to
             provide written informed consent before the first study related activity.

          -  Subject is willing to adhere to the visit/protocol schedules.

          -  Subject meets the diagnosis of gout as per the American Rheumatism Association
             Criteria for the Classification of Acute Arthritis of Primary Gout.

          -  Subject has been taking allopurinol at a dose of at least 300 mg daily for at least 12
             weeks prior to Day 1, as the sole uratelowering therapy.

        Exclusion Criteria:

          -  Subject who is pregnant or breastfeeding.

          -  Subject with any other medical or psychological condition, which in the opinion of the
             Investigator and/or Medical Monitor, might create undue risk to the subject or
             interfere with the subject's ability to comply with the protocol requirements
             (including dual energy computed tomography imaging), or to complete the study.

          -  Subject who has received an investigational therapy or has participated in any
             clinical trial or research study within 30 days of Day 1.

          -  Subject who has taken pegloticase (KRYSTEXXA®) or is expected to take pegloticase
             during the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessment of Skills and Behaviors in Children With Down Syndrome (NCT04754178)

Eligibility criteria:
Inclusion Criteria:

          -  Down syndrome childrens

          -  Age between 0 and 3 years

        Exclusion Criteria:

          -  Other physical or functional impairment that limits the performance of evaluation
No condition on gender to be admitted to the trial.


Subject must be at most 3 Years

Patient description (medical language): A 15-week-old infant brought to the clinic for the follow up. The infant has flat facies, small ears, a single palmar crease, and upward slanting eyes. He was born on 39th week to a 39-year-old woman who didn't have prenatal care. The medical record confirms the trisomy of chromosome 21 (Down syndrome). The infant is otherwise healthy.

Patient description (patient's own words): My newborn, who is only 15 weeks old, had one of his follow-up appointments. The doctor pointed out that my baby had a flat face, small ears, only one palm line, and small eyes. He was born on his 39th week, while I was 39. What a coincidence! To be honest, I did not go to the doctor during my pregnancy. The doctor diagnosed my baby with Down syndrome. Apart from that he's healthy.

Does the patient match the trial criteria? Entailment
Clinical trial: Unilateral Meniere Disease: Can Double Dose Gadolinium and Delayed Imaging Make the Diagnosis? (NCT02371798)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of unilateral Meniere Disease (MD) per the Committee on Hearing and
             Equilibrium of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS)

          -  Glomerular filtration rate (GFR) > 90 mls/min/1.73 m2

          -  Creatinine (Cr) level serum < 1.6 mg/dl

        Exclusion Criteria:

          -  Age < 18 years

          -  Diagnosis of bilateral MD

          -  History of prior temporal bone surgery

          -  History of cochlear implant placement

          -  Pacemaker, cardiac implantable electronic device, shrapnel, aneurysm clips or other
             metal objects that are prohibited in the MR suite

          -  GFR < 90 mls/min/1.73m2

          -  Cr level > 1.6 mg/d

          -  Lack of IV access

          -  Contrast allergy to gadolinium agent

          -  Pregnancy

          -  Claustrophobia necessitating parenteral anxiolytics

          -  Patients who are unable to provide informed consent for themselves
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient description (patient's own words): The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Does the patient match the trial criteria? Entailment