araag2/NLI4PR huggingface dataset:
Clinical trial: Physical Activity and Daily Experiences Study (NCT02005042)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 or older

          -  English literate

          -  A BMI ranging from 25-40 (overweight or obese), based on self-report height and weight

          -  Not meeting current national physical activity guidelines

          -  Self-report they are able to walk unassisted, without the help of a wheel chair,
             walker, cane, crutches, or other walking aids

          -  Medically cleared to participate by completing screening form

          -  For women: not currently pregnant or actively trying to get pregnant for duration of
             study

        Exclusion Criteria:

          -  Younger than 18

          -  Not English literate

          -  Self-report they are unable to walk unassisted, without the help of a wheel chair,
             walker, cane, crutches, or other walking aids

          -  A BMI outside of inclusion range (<25 or >40), based on self-report height and weight

          -  Meeting current national physical activity guidelines

          -  Not medically cleared to participate

          -  For women: currently pregnant or actively trying to get pregnant for duration of
             study. Pregnant women or those trying to become pregnant will be excluded because
             pregnancy may interfere with women's ability to go about previously normal activities,
             and will influence our outcome measures (e.g., BMI).
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Entailment
Clinical trial: SIBO & SIFO After Colectomy (NCT03216239)

Eligibility criteria:
Inclusion Criteria:

        patients who were referred to a specialist motility center over 4 year period with:

          -  Unexplained gastrointestinal symptoms such as gas, bloating, belching, diarrhea, and
             abdominal discomfort

          -  history of colectomy

          -  patients with no history of colectomy

          -  patients included who had normal: upper endoscopy, colonoscopy, computerized abdominal
             tomography scan, and normal hematology, biochemical profiles, tissue transglutaminase
             antibody, thyroid stimulating hormone, and normal right upper quadrant ultrasound
             scan.

          -  patients with glucose breath test and/or duodenal aspirate

        Exclusion Criteria:

          -  patients with upper gut or small bowel surgery

          -  Patients who were hospitalized or with serious cardiac or pulmonary or neurologic
             comorbidities

          -  Patients with intestinal strictures or known intestinal motility disorders such as
             scleroderma or pseudo-obstruction syndrome
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Contradiction
Clinical trial: Magnetic Resonance Imaging (MRI) of Brain Iron in Neurodegenerative Disease (NCT00249080)

Eligibility criteria:
Inclusion Criteria:

          -  18 years or older

          -  Healthy person without memory complaints OR person diagnosed with a neurodegenerative
             disease (ie, Alzheimer's disease, Parkinson's disease, multiple sclerosis)

        Exclusion Criteria:

          -  MR contraindication such as metal in body (ie, pacemaker, implant, shrapnel, etc.)

          -  Pregnant

          -  Claustrophobic anxieties
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass (NCT01572545)

Eligibility criteria:
Inclusion Criteria:

          -  Caucasian postmenopausal women older than 40 years

          -  Low bone mass at lumbar spine (L2-L4) or femoral neck (BMD T-score of ≤ -2.0) or BMD
             T-score of > -2.0 coexistent with low-energy fracture of vertebral, femoral neck or
             forearm

          -  Patient's informed consent to participate

        Exclusion Criteria:

          -  Secondary osteoporosis

          -  Any bone and mineral disorder other than osteoporosis, including primary or secondary
             hyperparathyroidism, Paget's disease of bone, osteogenesis imperfecta, rheumatologic
             diseases, paraplegia, chronic immobilization

          -  Severe liver or kidney disease (creatinine clearance < 60ml/min/1.73m2) or liver or
             kidney transplantation

          -  Premature ovarian failure

          -  Uncontrolled thyroid disease

          -  Any malignancy

          -  Any musculoskeletal injury or surgical procedure 6 months prior to baseline

          -  Dental surgery or teeth removed 3 months prior to baseline or plan to

          -  History or concomitant medications that could affect bone metabolism, including
             immunosuppressive, anticonvulsant, antiviral and anti-tuberculosis agents, addictive
             drugs, corticosteroids, non-steroidal anti-inflammatory drugs, amiodarone,
             thiazolidinediones, interferon, metronidazole, and tamoxifen
Female
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Long-Term Safety and Efficacy of SPK-8011 in Males With Hemophilia A (NCT03432520)

Eligibility criteria:
Inclusion Criteria:

          1. Males with hemophilia A, who have received a single intravenous administration of
             SPK-8011 in any Spark sponsored SPK-8011 study

          2. Individuals who understand the purpose and the risks of the study, and who provide
             signed and dated informed consent before undergoing any study-specific procedures.

        Exclusion Criteria:

        1. Individuals who are unable or unwilling to comply with the schedule of visits and study
        assessments as described in this study protocol.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Evaluating a Telemedicine Smoking Cessation Program in Rural Primary Care Practices (NCT00843505)

Eligibility criteria:
Inclusion Criteria:

          -  Smokes cigarettes every day

          -  Smokes five or more cigarettes per day

          -  Has smoked cigarettes for at least 1 year before study entry

          -  Has a home address and phone number

          -  Willing to participate in phone assessments

          -  Willing to be assigned to either of the two study programs

        Exclusion Criteria:

          -  Pregnant or breastfeeding

          -  Another household member is enrolled in the study

          -  Moving out of the area of residence in the 14 months after study entry

          -  Primary care provider is not participating in the study

          -  Use of other forms of tobacco products (e.g., cigars, spit, snuff) in addition to
             cigarettes

          -  Use of a smoking cessation medication
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: Early Rehabilitation After Hand or Wrist Ambulatory Surgery : How to Preserve Locomotion at Home Without Rebound Pain? (NCT04306666)

Eligibility criteria:
Inclusion Criteria:

        - All adults patients scheduled for hand or wrist ambulatory surgery since 2016

        Exclusion criteria:

        - NA
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: TEAM: Testosterone Supplementation and Exercise in Elderly Men (NCT00112151)

Eligibility criteria:
Inclusion Criteria:

          -  Generally healthy, untrained men 60 years or older with low-normal testosterone levels
             (200-350ng/dL)

          -  Must reside in the Denver metro area

        Exclusion Criteria:

          -  Prostate/breast cancer

          -  Unable to exercise safely

          -  severe obesity (>34 body mass index [BMI])

          -  Polycythemia

          -  Diabetes

          -  Use of drugs that could affect T levels

          -  Cognitive dysfunction (MMSE less than 24)

          -  PSA above the age-adjusted normal level or AUA greater than 19

          -  Unable to pass stress test due to active CAD
Male
Accepts Healthy Volunteers
Subject must be at least 60 Years old.


Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Laparoscopic Versus Transvaginal Cuff Closure (NCT03898726)

Eligibility criteria:
Inclusion Criteria:

          1. Patients candidate for total laparoscopic hysterectomy :

               -  Uterine size <12 weeks.

               -  Having no severe endometriosis.

               -  Having descent of no more than 1st degree of uterus.

               -  Non-malignant conditions.

          2. Completion of the entire procedure by laparoscopic approach up to colpotomy.

          3. Benign conditions as indications for hysterectomy.

        Exclusion Criteria:

        - 1) Obese patients i.e., BMI > 30 k.g\m2. 2) Suspected extensive pelvic adhesions . 3)
        Factors which may prolong wound healing as uncontrolled diabetes, ,prolonged corticosteroid
        therapy ,advanced liver diseases.

        4) Inability to express adequate informed consent to participate in the study.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer (NCT00002615)

Eligibility criteria:
DISEASE CHARACTERISTICS:

          -  Histologically proven resectable stage II or III adenocarcinoma of the stomach

          -  No evidence of locally inoperable or distant metastases on chest x-ray and any
             combination of abdominal ultrasound, CT scan, or laparoscopy

        PATIENT CHARACTERISTICS:

        Age:

          -  Any age

        Performance status:

          -  WHO 0-1

        Hematopoietic:

          -  Not specified

        Hepatic:

          -  Not specified

        Renal:

          -  Creatinine clearance greater than 60 mL/min

        Cardiovascular:

          -  No clinical evidence of uncontrolled angina pectoris, cardiac failure, or significant
             uncontrolled cardiac arrhythmia

        Other:

          -  No medical contraindication to study therapy

          -  No other prior malignancy except nonmelanomatous skin cancer or carcinoma in situ of
             the cervix

          -  Not pregnant

        PRIOR CONCURRENT THERAPY:

        Biologic therapy:

          -  Not specified

        Chemotherapy:

          -  No prior chemotherapy

        Endocrine therapy:

          -  Not specified

        Radiotherapy:

          -  No prior radiotherapy

        Surgery:

          -  See Disease Characteristics
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment