araag2/NLI4PR huggingface dataset:
Clinical trial: Efficacy/Safety of Lansoprazole in Patients With Frequent Nighttime Heartburn (NCT00701259)

Eligibility criteria:
Inclusion Criteria:

          -  Experiencing heartburn at least 2 days per week during the nighttime period over the
             past month.

          -  Having heartburn that responds to heartburn medication.

          -  Be willing to discontinue the use of heartburn treatment for 7 days prior to inclusion
             in the study.

        Exclusion Criteria:

          -  Having history of erosive esophagitis or gastroesophageal reflux disease diagnosed by
             a physician and confirmed by testing (endoscopy).

          -  Be unwilling to take only the study medication, and antacid provided as a rescue
             medication for relief of acute heartburn during the study.

        "Other protocol-defined inclusion/exclusion criteria may apply"
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Cohort of Patients Infected With SARS-CoV2 (COVID-19) or Suspected of Being (NCT04352348)

Eligibility criteria:
Inclusion Criteria:

          -  Age ≥ 18

          -  Patient admitted in an emergency unit or hospitalized, infected with SARS-CoV2 or
             suspected of being (the recruitment can occured during acute episode or during a
             follow-up visit)

          -  Written informed consent or emergency procedure

          -  Affiliated to health insurance system

        Exclusion Criteria:

          -  Refusal of participation

          -  Patient under justice protection measure except guardianship and trusteeship
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux Patients (NCT00524251)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with reflux complaints

          -  18 years of age

        Exclusion Criteria:

          -  Restrictions as mentioned in the registration text

          -  H2RA or PPI use in the month prior to inclusion
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Caudal Block Versus Ultrasound Guided Ilioinguinal/Iliohypogastric Block in Pediatric Patient (NCT03258736)

Eligibility criteria:
Inclusion Criteria:1- 10 year- old who were scheduled to bilateral inguinal hernia surgery
        -

        Exclusion Criteria: Patients with neurological disoder, reoperation for inguinal hernia
        surgery, coagulation disorder

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 10 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator (NCT00422643)

Eligibility criteria:
Inclusion criteria:

          -  Patients with the diagnosis of Osteoarhtritis of the knee, graded according to
             Kellgren as grade 1-4

        Exclusion criteria:

          -  Patients that suffer from acute septic arthritis.

          -  Patients that treated with coumadin and/or other anti-coagulant drugs

          -  Patients that show mental or physical conditions, which preclude compliance with study
             and/or device.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: Clinical Audit on Evaluation of Patient With Syncope at Asssiut University Children Hospital (NCT04575376)

Eligibility criteria:
Inclusion Criteria:

          -  all cases of syncope.

        Exclusion Criteria:

        -
No condition on gender to be admitted to the trial.

Subject must be at least 1 Year old.
Subject must be at most 18 Years

Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis (NCT04335058)

Eligibility criteria:
Inclusion Criteria:

          1. Age 18-75 years

          2. Either gender

          3. Patients with chronic liver disease with iron deficiency anemia with transferrin
             saturation<20% and Hemoglobin in Non-pregnant women (15 years of age and above)
             <12g/dl and in men <13g/dl -

        Exclusion Criteria:

          1. Those who do not consent to participate in the study

          2. Inability to obtain informed consent from patient or relatives

          3. Severe preexisting cardiopulmonary disease

          4. Renal dysfunction (S. Creatinine ≥ 2mg/dL)

          5. Pregnancy/Lactation

          6. Post liver transplant patients

          7. HIV infection

          8. Patients who are on psychoactive drugs, like sedatives or antidepressants

          9. Patients who are too sick to carry out the protocol
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 51-year-old man comes to the office complaining of fatigue and some sexual problems including lack of libido. The patient doesn't smoke or use any illicit drug.  Blood pressure is 120/80 mm Hg and pulse is 70/min.  Oxygen saturation is 99% on room air.  BMI is 24 kg/m2.  Skin examination shows increased pigmentation. Genotype testing is consistent with homozygosity for the C282Y mutation. Laboratory study shows transferrin saturation of 55% and serum ferritin of 550 μg/L. He is diagnosed as a case of hemochromatosis.

Patient description (patient's own words): I am 51 years old and I just came back from the doctor's office. I'm sick and tired of being that exhausted, reaching the point where me and my lovely wife are not touching each other anymore! I'm not smoking or doing drugs! My blood pressure was 120/80 mm Hg, and pulse was 70/min and my oxygen saturation 99%. My BMI is 24. My skin also turned a bit darker lately. He tested my genes and told me that I have a mutation of the C282Y gene. I also did lab tests where my transferrin saturation was 55% and serum ferritin was 550  μg/L. The doctor diagnosed me with iron overload.

Does the patient match the trial criteria? Contradiction
Clinical trial: Syncope Decision Aid for Emergency Care (NCT02971163)

Eligibility criteria:
Inclusion Criteria:

          -  Emergency Department patient

          -  Age 30 years or above

          -  Chief complaint of syncope

          -  Capacity to make medical decisions

          -  Speak and read English

          -  Working phone number and fixed address

        Exclusion Criteria:

          -  Altered Mental Status

          -  Cognitive Impairment

          -  Serious acute diagnosis:

             (e.g. clinically significant cardiac dysrhythmia, structural heart disease,
             gastrointestinal hemorrhage, myocardial infarction, pulmonary embolism, pneumonia,
             arterial dissection, serious infection, ectopic pregnancy, subarachnoid hemorrhage, or
             stroke.)

          -  Hemodynamic instability

          -  Inability to read or speak English

          -  Major communication barrier

          -  Lack of phone number or fixed address

          -  Too high risk as per physician judgment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Contradiction
Clinical trial: Clinical Study of in Situ Regeneration of Endometrium (NCT04233892)

Eligibility criteria:
Inclusion Criteria:

        1.Patients with thin endometrium (4mm≤ EMT <7mm )or scarred endometrium (scarred area≤70%)
        which is nonresponsive to estrogen stimulation 2.Infertile patients with clear fertility
        desires 3.20-42 years old 4.Normal ovarian function or with frozen embryos 5.Willing to
        participate in follow-up

        Exclusion Criteria:

          1. Endometrial thickness <4mm or scarred endometrial area>70%

          2. Uterine cavity out of shape and the cavity depth<6.5mm

          3. Abnormal chromosome karyotype

          4. Uterine diseases including large intramural myomas, severe endometriosis, severe
             adenomyosis, severe congenital uterine malformations, endometrial tuberculosis,
             vaginitis and endometritis

          5. Systemic diseases: hypertension, diabetes, and so on

          6. Contraindications to pregnancy

          7. Contraindications to hormone replacement therapy

          8. Medical history of pelvic tumors or receiving pelvic radiotherapy 9 .Involved in other
             clinical studies

        10. Unable to adhere to the follow-up
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 42 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Entailment
Clinical trial: A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery (NCT04805229)

Eligibility criteria:
Inclusion Criteria:

          -  Adult patients (18 years and older)

          -  Patients undergoing one of the following procedures: laparoscopic cholecystectomy,
             laparoscopic appendectomy, minor hernia repair (including laparoscopic or open
             inguinal, femoral, umbilical, and epigastric hernia repair), open and laparoscopic
             ventral/incisional hernia repair, laparoscopic colectomy, open colectomy, vaginal
             hysterectomy, laparoscopic hysterectomy, and open abdominal hysterectomy

          -  Patients who underwent surgery between January 1, 2013 and December 31, 2019

        Exclusion Criteria:

          -  Patients who are not opioid-naive at the time of surgery, defined as filling 1 or more
             opioid prescriptions between the 12 months to 31 days prior to surgery

          -  Patients without continuous insurance enrollment for at least 12 months before and at
             least 6 months after the date of surgery

          -  Patients still in the hospital on postoperative day 30

          -  Patients not discharged home after surgery

          -  Patients who underwent another surgery within 6 months of their index operation
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Identification and Characterization of the Biomarker in Synovial Fluid for Hyaluronic Acid Therapy in Osteoarthritis (NCT01813916)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of osteoarthritis

          -  Accept the intra-articular HA injection therapy

        Exclusion Criteria:

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment