araag2/NLI4PR huggingface dataset:
Clinical trial: Family SuppleMented pAtient monitoRing afTEr suRgery: A Pilot Trial (NCT04341558)

Eligibility criteria:
Inclusion Criteria:

        Patients:

        • Patients ≥5 years of age undergoing surgery at Mbale Regional Referral Hospital, who
        receive post-operative care in one of four main surgical wards, with a family carer
        prepared to participate in the trial intervention.

        Carers:

          -  All carers will be included in the trial if they feel they are capable of performing
             and documenting the basic vital signs provided they agree to participate in the trial.

          -  The ability to speak English, Luganda, Lugisu, Ateso or Lugwere

          -  The ability to read a digital clock (to measure vital signs)

          -  Numeracy sufficient to write numbers on the basic observation chart

        Exclusion Criteria:

        Patients:

          -  Refusal of informed consent.

          -  Identification of potential participant >24hours after operative procedure has taken
             place

        Carers:

        • Refusal of informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 5 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Effectiveness and Adherence to Closed Face Shields to Prevent COVID-19 Transmission (NCT04647305)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 years or older

          -  Negative RT-PCR test at the beginning of the study.

          -  Negative SARS-CoV-2 serological Elecsys Anti-Sars-CoV-2 test at the beginning of the
             study.

          -  Living in a geographic area with active COVID-19 transmission (number of

          -  cases reported locally).

          -  Living in a geographic area that has been determined by the Colombian National
             Statistics Department (DANE) to have a medium, medium-high, and high vulnerability
             index (higher prevalence of comorbidities and social and economic vulnerabilities.

          -  Working outside the home for at least two days a week, during the last week.

          -  Acceptance to participate in the study regardless of the trial arm assignment through
             verbal informed consent.

        Exclusion Criteria:

          -  Retired adults or unemployed

          -  Adults referring previous diagnosis of COVID-19 confirmed by RT-PCR tests or
             serological antibody tests.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Laparoscopic Hernia Repair With Lateral Umbilicus Ligament for Children (NCT01377181)

Eligibility criteria:
Inclusion Criteria:

          -  unilateral inguinal hernia

          -  age between 2 years and 17 years

          -  no history of abdominal or inguinal operations

          -  the age range was based on the day surgery criteria of our hospital

          -  of male patients, only those with completely descended testes were included

        Exclusion Criteria:

          -  the bilateral hernia

          -  the recurrence hernia
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 2 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Contradiction
Clinical trial: Study of Hypercortisolism in Cushing's Syndrome and Stress-Induced Pseudo-Cushing's Syndrome (NCT00004343)

Eligibility criteria:
PROTOCOL ENTRY CRITERIA:

        Suspected adrenocorticotropin hormone (ACTH)-dependent Cushing's syndrome No pregnant women
        Effective contraception required of fertile women
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 47-year-old man comes to the office due to weight gain and fatigue.  He is not able to lift heavy objects or climb stairs. Family history is positive for DM type 2 and HTN in his father.  Blood pressure is 165/90 mm Hg and pulse is 85/min.  On physical examination, there is symmetric proximal muscle weakness of the upper and lower extremities.  Fasting plasma glucose level is 138 mg/dL and 24-hour urinary cortisol is twice the upper normal limit.  Further evaluation reveals that high-dose, but not low-dose, dexamethasone suppresses serum cortisol levels.  Serum ACTH levels are high-normal. This patient's findings are consistent with endogenous Cushing Syndrome.

Patient description (patient's own words): I'm a 47-year-old man. I went to the clinic because I had been gaining weight and had increased fatigue over the past few weeks. I was not able to lift heavy objects or even climb the stairs. My dad was diagnosed with type 2 diabetes and high blood pressure. During the exam, they took my blood pressure, which was 165/90 mm Hg, and my pulse was 85/min. They found out that I have weaknesses in both of my arms and legs. I also did a blood test on an empty stomach, and I had a glucose level of 138 mg/dL, and twice the upper normal limit of cortisol. I had high-normal levels of ACTH. The doctor said I suffer from endogenous Cushing Syndrome.

Does the patient match the trial criteria? Entailment
Clinical trial: Survey of Inhibitors in Plasma-Product Exposed Toddlers (NCT01064284)

Eligibility criteria:
Inclusion Criteria:

          -  Male subjects

          -  Any ethnicity

          -  Age <6 years

          -  Severe haemophilia A (FVIII:C <1%), as confirmed at enrolment by the central
             laboratory.

             o Those patients diagnosed locally as severe but subsequently found to have FVIII
             levels >= 1% on testing at the central laboratory will be separately recorded in the
             screening list.

          -  Previously untreated (0 EDs to any FVIII concentrates or blood products) or minimally
             treated (<5 EDs) with blood components, namely whole blood, fresh frozen plasma,
             packed red blood cells, platelets or cryoprecipitate.

             o Patients not meeting these criteria will be separately recorded in the screening
             list.

          -  Negative inhibitor measurement at both local and central laboratory at screening

          -  Ability to comply with study requirements

          -  Signed informed consent of legal tutors o Patients who will not accept to enter into
             the study or to be randomized will be separately recorded.

        Exclusion Criteria:

          -  Previous history of FVIII inhibitor

          -  Other congenital or acquired bleeding defects

          -  Plasma FVIII level >= 1%, as assayed at the central laboratory

             o Those patients originally diagnosed locally as severe but subsequently found to have
             FVIII levels ranging from 1% to 2% on testing at the central laboratory will be
             separately recorded in the screening list.

          -  Concomitant congenital or acquired immunodeficiency

          -  Concomitant treatment with systemic immunosuppressive drugs

          -  Concomitant treatment with any investigational drug
Male
No healthy subjects accepted to join the trial.

Subject must be at most 6 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Demographics and Findings of Upper Endoscopy Patients (NCT00576992)

Eligibility criteria:
Inclusion Criteria:

          -  Patients who present to the KCVA GI endoscopy unit with symptoms of reflux,upper
             abdominal pain, anemia (patients referred by their primary care physicians with a
             diagnosis of low hemoglobin (< 10 G/DL, and or dyspepsia

        Exclusion Criteria:

          -  Weight loss (Weight loss of > 10% of their mean body weight over last 6 months)

          -  Dysphagia

          -  Gastrointestinal bleeding

          -  Gastrointestinal malignancy

          -  Recent EGD (in the past 5 years)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Contradiction
Clinical trial: Interventional Trial of Vitamin D Deficiency in the Patients of General Departments (NCT00640237)

Eligibility criteria:
Inclusion Criteria:

          -  the patient was admitted to a general department of Rambam Medical Center for any
             reason from March to May 2008

          -  the patient is 65 years old or older

          -  the patient is in a good health, based on medical history, physical examination and
             laboratory screening evaluation.

        Exclusion Criteria:

          -  renal failure with creatinine level more then 1.3 mg/dL or nephritic syndrome.

          -  liver disease with transaminase rise three times from normal level.

          -  nephrolithiasis in the last fife years.

          -  primary hyperparathyroidism, hypoparathyroidism or pseudohypoparathyroidism.

          -  advanced cancer.

          -  chronic diarrhea or malabsorption.

          -  granulomatous disease (sarcoidosis, tuberculosis, lymphoma).

          -  patients, who are receiving barbiturates, rifampin, anticonvulsants.

          -  patients, who are receiving digitalis.

          -  patients, who are receiving glucocorticoids for more than two weeks during the study.

          -  advanced dementia.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessment of Tremor Using SNUMAP Motion Sensing System (NCT01731145)

Eligibility criteria:
Inclusion Criteria:

          -  Age: 20-80 years

          -  Patients with tremor (involuntary, rhythmic, oscillatory movement in one or more body
             part)

          -  Subject who signed an informed consent

        Exclusion Criteria:

          -  Pregnant or nursing woman.

          -  Comorbid neurologic illnesses that impact the ability to perform the study tasks.

          -  Subjects with medical condition that in the opinion of the investigator would affect
             his/her ability to participate in this study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: The Effect of Dual Trigger for Final Oocyte Maturation on IVF/ICSI Outcomes in Patients With Suboptimal Ovarian Response (NCT04549649)

Eligibility criteria:
Inclusion Criteria:

        Patients with poor ovarian response (POR) diagnosis according to the POSEIDON
        stratification system (as POSEIDON group 1) with following criteria :

          -  Women' age under 35 years;

          -  Previous unexpected poor or suboptimal ovarian response after using conventional
             protocols (subgroup 1a: < 4 oocytes ) and (subgroup 1b: 4-9 oocytes retrieved)

          -  Adequate ovarian reserve (antral follicle count ≥5 on menstrual cycle day 2-3; and
             basal serum AMH ≥ 1.2 ng/ml)

        Exclusion Criteria:

          -  Ovarian failure including basal FSH above 20 IU/l or no antral follicle by ultrasound
             examination;

          -  Endometriosis grade 3 or higher;

          -  Severe male infertility (surgical sperm extraction: TESE, PESA)

          -  Body mass index >30 kg/ m2

          -  History of uterine surgery as well as sub-mucosal and intramural fibroids greater than
             5 cm or uterine polyps

          -  Treatment cycles with pre-implantation genetic diagnosis, blastocyst and donation
             embryo transfer indications

          -  Cigarette and drug addiction
Female
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Atropine for Children and Adolescent Myopia Progression Study (NCT03949101)

Eligibility criteria:
Inclusion Criteria:

          -  children aged from 7-12 years old;

          -  children with spherical equivalent ranged from -0.5D to -6.0D;

          -  children without other eye diseases except for ametropia

        Exclusion Criteria:

          -  children with other eye diseases: amblyopia, strabismus, eye trauma, etc;

          -  children with cycloplegia contradictions;

          -  children who have used atropine;

          -  children who are severly allergic with atropine;

          -  children who are using other eye drops for treatment;

          -  children with severe heart, lung, liver and kidney diseases.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.
Subject must be at most 12 Years

Patient description (medical language): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient description (patient's own words): I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Does the patient match the trial criteria? Contradiction