araag2/NLI4PR huggingface dataset:
Clinical trial: Intraoperative Imaging of Pulmonary Nodules by OTL38 (NCT02602119)

Eligibility criteria:
Inclusion Criteria:

          -  Adult patients over 18 years of age

          -  Patients presenting with a lung or pleural nodule or mass presumed to be resectable on
             pre- operative assessment

          -  Good operative candidate

          -  Subject capable of giving informed consent and participating in the process of
             consent.

        Exclusion Criteria:

          -  Pregnant women as determined by urinary or serum beta hCG within 72 hours of surgery

          -  Patients with a history of anaphylactic reactions to OTL38

          -  Patients with a known allergy to Benadryl

          -  At-risk patient populations:

               -  Homeless patients

               -  Patients with drug or alcohol dependence

               -  Children and neonates

               -  Patients unable to participate in the consent process.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism (NCT00290134)

Eligibility criteria:
Inclusion Criteria:

          -  Total testosterone level <240 ng/dL

          -  Serum LH and FSH levels within normal limits

        Exclusion Criteria:

          -  Elevated prolactin

          -  Evidence of Benign Prostatic Hypertrophy

          -  History of or current breast cancer, prostate cancer, abnormal DRE or elevated PSA or
             any other malignancy

          -  Clinically significant endocrine/metabolic or cardiovascular disease

          -  Significant polycythemia
Male
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effect of Inhaled N-Acetylcysteine Compared to Normal Saline on Sputum Rheology and Lung Function (NCT00996424)

Eligibility criteria:
Inclusion Criteria:

          -  Patients who can perform lung function tests and who can produce sputum (> 5 years of
             age)

          -  (Fe)males between 6-64 years

        Exclusion Criteria:

          -  Patients on the waiting lists for lung transplant.

          -  Pregnancy or breast feeding

          -  Patients can not take part in another 'inhalation'trial for Cystic Fibrosis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Years old.
Subject must be at most 64 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Quantitative Muscle Ultrasound as a Marker of Progression in Children With Muscular Diseases (NCT03786913)

Eligibility criteria:
Inclusion Criteria:

          -  children with Duchenne muscular dystrophy (DMD). Diagnosis with DMD was established
             according to DMD diagnostic criteria (Jennekens et al., 1991).

          -  children with juvenile dermatomyositis (JDM) according to Bohan and Peter diagnostic
             criteria ( (Bohan and Peter, 1975).

        Exclusion Criteria:

          -  Patients with age less than 2 years were excluded from the study due to inability to
             perform manual muscle testing and functional scales.

          -  If no final diagnosis could be established.

          -  The presence of a concomitant illness that may result in peripheral neuropathy or
             myopathy.
No condition on gender to be admitted to the trial.

Subject must be at least 2 Years old.
Subject must be at most 16 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? Entailment
Clinical trial: Individually Tailored Web-Based Program to Improve Blood Pressure Control (NCT00377208)

Eligibility criteria:
Inclusion Criteria:

          -  History of hypertension

          -  At least one blood pressure value that is greater than recommended in the year prior
             to study entry

          -  An enrolled physician has provided care for managing the participant's blood pressure
             for at least 1 year prior to study entry

          -  Access to the internet at home or at work

          -  Personal email account

          -  At least one blood pressure value greater than 140/90 mm Hg (130/90 mm HG for diabetes
             patients) in the one year prior to study entry

        Exclusion Criteria:

          -  Unable to speak and read English

          -  Pregnant or plans to become pregnant in the year following study entry

          -  Cognitively impaired

          -  Currently incarcerated

          -  Participating in another clinical research study

          -  Planning on moving out of the area in the year following study entry
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 21 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Lateral Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Laparoscopic Surgery (NCT04553991)

Eligibility criteria:
Inclusion Criteria:

          -  Patients scheduled for elective laparoscopic abdominal surgeries (inguinal hernia
             repair-missed IUCD extraction-appendectomy-ovarian vein ligation)

          -  Patient aged 18-60 years

          -  American Society of Anesthesiologists Physical Status I or II.

        Exclusion Criteria:

          -  Patient refusal

          -  Body mass index (BMI) > 40 kilogram/square meter

          -  Contraindication to regional anesthesia (coagulopathy, allergy to local anesthetic,
             sever thrombocytopenia or infection at puncture site)

          -  Sepsis

          -  Chronic pain condition requiring the intake of opioids at home

          -  Any significant neurological, cardiovascular or respiratory disease.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Program to Prevent Osteoporosis in Girls (NCT00063024)

Eligibility criteria:
Inclusion Criteria

          -  Member of a Girl Scout troop with at least eight 5th grade girls

          -  Member of the Greater Minneapolis or St. Croix Valley Girl Scout organization

          -  Only troops with unanimous parental consent will be included in the trial
Female
Accepts Healthy Volunteers
Subject must be at least 9 Years old.
Subject must be at most 11 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: Von Willebrand Disease in the Netherlands (NCT03521583)

Eligibility criteria:
Inclusion Criteria:

          -  Historically lowest VWF:Ag and/or VWF:RCo and/or VWF:CB ≤ 0.30 IU/mL and/or FVIII:C ≤
             0.40 IU/mL

          -  Treatment at a Hemophilia treatment center in the Netherlands

          -  All types of VWD

          -  All ages

        Exclusion Criteria:

        - Other known bleeding disorders present.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Ilioinguinal Block in Laparoscopic Inguinal Hernia Repair (NCT01969006)

Eligibility criteria:
Inclusion Criteria:

          1. Age ≥ 18 year

          2. Informed consent

          3. a diagnosis of an inguinal hernia

          4. ASA group ≤ 3

          5. BMI ≤ 35

        Exclusion Criteria:

          1. Communication problems

          2. No consent

          3. Open procedure (not laparoscopic)

          4. ASA-group 4

          5. Use of Steroid or immunosuppressive tretament

          6. Regular morphine use.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Screening for Glaucoma in Namil Area, South Korea (NCT00727168)

Eligibility criteria:
Inclusion Criteria:

          -  All residents aged over 40 in Namil area

        Exclusion Criteria:

          -  Individuals registered but not actually living in this area
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.


Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Entailment
Clinical trial: Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) Symptoms (NCT00730106)

Eligibility criteria:
Inclusion Criteria:

          -  outpatients

          -  chief complaints of characteristic GERD symptoms (heart burn or acid regurgitation),
             evaluated by standard questionnaire

          -  undergo upper digestive endoscopy

        Exclusion Criteria:

          -  age less than 18 years old or more than 90 years old

          -  unable to complete upper endoscopy

          -  known diagnosis of gastroesophageal malignancy

          -  follow-up visit for known gastroesophageal lesion identified by previous upper
             endoscopy

          -  failure to obtain informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Contradiction