araag2/NLI4PR huggingface dataset:
Clinical trial: Expressive Writing in Male Infertility (NCT00385346)

Eligibility criteria:
Inclusion Criteria:

          -  Male infertile patients with a pathological spermiogram according to WHO criteria

        Exclusion Criteria:

          -  Drugs affecting sperm quality

          -  Patients with chromosomal anomalies affecting sperm quality (e.g. Klinefelter-
             Syndrome)

          -  Severe Psychiatric disorder defined as psychotic disorder (schizophrenia, bipolar
             disorder) or substance-related disorder

          -  Patients currently in psychotherapeutic or psychiatric therapy
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Impact of Air Pollution on Chronic Respiratory Diseases (NCT03813810)

Eligibility criteria:
Inclusion Criteria:

          -  Normal: People with no lung lesions in chest X-ray and St. George's Respiratory
             Questionnaire score <25, and post bronchodilator FEV1/FVC (forced expiratory volume at
             one second/forced vital capacity) >= 0.7 and FEV1 >= 80% and FVC >= 80%.

          -  Chronic obstructive pulmonary disease: Patients with over 10 pack-years of smoking
             history and post bronchodilator FEV1/FVC <0.7 and FEV1 < 80%, and no other reason for
             decline of lung function.

          -  Asthma: Patients with FEV1/FVC < 0.85 and increase in over 12% and 200mL of FEV1 by
             bronchodilator inhalation. Patients with P20 < 16mg/dL by bronchial provocation test.

          -  Idiopathic pulmonary fibrosis: Shows usual interstitial pneumonia according to chest
             CT and has no other reasons such as systematic diseases or medication history.

        Exclusion Criteria:

          -  Subjects who refused for enrollment in the study

          -  Subjects who experienced an acute exacerbation within 1 month.

          -  Subjects under age of 19.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 19 Years old.


Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation (NCT01073605)

Eligibility criteria:
Inclusion Criteria:

          -  Chronological age (CA) between 3 and 10 for girls

          -  Chronological age between 3 and 12 for boys

          -  Height for CA below - 2 SD

          -  Birth length for CA below -2SD

        Exclusion Criteria:

          -  Endocrine disease except well-substituted hypothyroidism

          -  Sever chronic disease

          -  Skeletal dysplasia

          -  Known chromosomal aberration

          -  Ongoing treatment with steroids

          -  Known intrauterine infection
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.
Subject must be at most 12 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effect of the Number of Needle Revolutions Inside the Node on the Diagnostic Yield of EBUS-TBNA in Sarcoidosis (NCT02875756)

Eligibility criteria:
Inclusion Criteria:

          -  Age group of 18 to 65 years

          -  Clinicoradiological suspicion of sarcoidosis where EBUS-TBNA is being planned

          -  Enlarged hilar and mediastinal lymph nodes >10 mm (any axis) on computed tomography of
             the chest

        Exclusion Criteria:

          -  Hypoxemia (SpO2 <92% on FiO2 of 0.3)

          -  Treatment with systemic glucocorticoids for >2 weeks in the preceding three months

          -  Diagnosis of sarcoidosis possible with another minimally invasive technique such as
             skin biopsy or peripheral lymph node biopsy

          -  Failure to provide informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding Disorders (NCT00904709)

Eligibility criteria:
Inclusion Criteria:Clinical diagnosis of Menorrhagia

          -  Must be able to swallow tablets

        Exclusion Criteria:

          -  Endometrial abnormality

          -  Pelvic infection

          -  Pregnancy

          -  Breast Feeding

          -  Requirement for birth control

          -  Known intolerance/lack of effect of tranexamic acid
Female
Accepts Healthy Volunteers
Subject must be at least 15 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Autostereoscopic Dynamic Near Vision Testing (NCT04606355)

Eligibility criteria:
Inclusion Criteria:

          -  Normal subjects, patients with deficient binocular vision, patients with color vision
             disorders

        Exclusion Criteria:

          -  phthisis, enucleations
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 1 Year old.
Subject must be at most 95 Years

Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Entailment
Clinical trial: Effects of Closed and Open Kinetic Chain Exercises (NCT04186143)

Eligibility criteria:
Inclusion Criteria:

          -  the presence of knee osteoarthritis Grade 2 and Grade 3 based on Kellgren Lawrence
             Classification,

          -  volunteering to participate in the study.

        Exclusion Criteria:

          -  the presence of active synovitis,

          -  participation physiotherapy program in the last 6 months,

          -  systemic and cardiovascular diseases,

          -  neurological and orthopedic problems affecting walking and standing,

          -  lower extremity surgery
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessment of the Transfer of Using Levonorgestrel Intrauterine System (LNG IUS) as a Contraceptive to Using it as Part of Hormone Replacement Therapy (HRT). (NCT00185458)

Eligibility criteria:
Inclusion Criteria:

          -  Women with intact uterus, regular menstrual cycles and no previous or current
             climacteric symptoms.

        Exclusion Criteria:

          -  Pregnancy or lactation.

          -  Previous pelvic infections.

          -  Abnormal bleeding.

          -  Abnormal uterine cavity.

          -  Uterine polyps.

          -  Genital cancer.

          -  Liver diseases.

          -  Alcoholism or drug abuse.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 46 Years old.
Subject must be at most 51 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Dietary Treatments for Cognitive Impairment in Older Adults (NCT02521818)

Eligibility criteria:
Inclusion Criteria:

          -  diagnosis of mild cognitive impairment or Alzheimer's disease

          -  availability of cohabitating study partner without cognitive impairment

          -  consent of primary care physician

        Exclusion Criteria:

          -  history of stroke

          -  history of coronary artery disease

          -  history of pancreatitis

          -  untreated hypothyroidism or B12 deficiency

          -  history of renal disease or recurrent kidney stones

          -  history of liver disease

          -  insulin-dependent diabetes

          -  body mass index <18.5

          -  multiple food allergies

          -  follow strict diet (e.g., vegetarian, gluten-free)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 60 Years old.


Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? Entailment
Clinical trial: Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation (NCT04342728)

Eligibility criteria:
Inclusion Criteria:

          -  Outpatients ≥ 18 years presenting to Cleveland Clinic Health System in Ohio and
             Florida who test positive for COVID-19 having any of the following symptoms

               1. Fever or chills

               2. Shortness of breath or difficulty breathing

               3. Cough

               4. Fatigue

               5. Muscle or body Aches

               6. Headache

               7. New loss of taste

               8. New loss of smell

               9. Congestion or runny nose

              10. Nausea

              11. Vomiting

              12. Diarrhea

        Women of child bearing potential:

          1. have had a menstrual period within the past 30 days, or

          2. have had previous sterilization, or

          3. are perimenopausal (less than 1 year) who have a negative pregnancy test, or

          4. women of childbearing potential who do not meet the above and have a negative
             pregnancy test.

        Exclusion Criteria:

          -  Patients who are found to be positive during hospitalization

          -  Patients who reside outside Ohio or Florida.

          -  Pregnant women:

               1. Current known pregnancy

               2. Positive pregnancy test (women of child bearing potential who have not had
                  previous sterilization as defined as hysterectomy or tubal ligation)

          -  Women of childbearing potential who do not meet the above criteria, last menstrual
             period greater than 30 days and have a positive pregnancy test.

          -  Lactating Women

          -  End stage kidney disease

          -  Advanced liver disease awaiting transplant

          -  History of Calcium Oxalate kidney stones.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment