araag2/NLI4PR huggingface dataset:
Clinical trial: Advanced Methods for Cancer Detection by Vaginal Screening (NCT02622776)

Eligibility criteria:
Inclusion Criteria:

        Ovarian Cancer and Endometrial Cancer cases:

          1. Women age 19 or older.

          2. Histologically confirmed high grade serous cancer (had a pre-operative core biopsy) of
             ovarian/fallopian tube/peritoneal origin or histo-cytologically confirmed endometrial
             cancer, not yet treated by surgery or chemotherapy.

          3. Give consent to access primary tumour tissue following surgery or biopsy.

        Healthy participants:

        1) Healthy women between the ages of 19 and 60.

        Exclusion Criteria:

        Ovarian Cancer and Endometrial Cancer cases:

          1. Women with self-reported, known pregnancy.

             Healthy participants:

          2. Women with a prior diagnosis of gynecologic malignancy (ovarian, endometrial,
             cervical, or vulvar cancer) will be excluded.

          3. Women who report irregular bleeding (spotting between menstrual cycles, or
             post-menopausal bleeding), or who have self-reported gynecologic concerns (e.g. pelvic
             pain, pelvic masses, dyspareunia) or have had a recent evaluation for gynecologic
             concerns (consultation with a gynecologist, pelvic ultrasound, endometrial biopsy) are
             ineligible.

          4. Women with known Lynch Syndrome and/or BRCA1 or BRCA2 germline mutations will not be
             eligible to participate as healthy volunteers for this study.

          5. Women with self-reported, known pregnancy.
Female
Accepts Healthy Volunteers
Subject must be at least 19 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Sonographic Signs of Gouty Arthritis in a Cohort of Egyptian Patients: a Cross Sectional Multicenter Study (NCT04734093)

Eligibility criteria:
Inclusion Criteria:

          -  mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal

          -  patients with a known history of gout or at high risk

        Exclusion Criteria:

          -  Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjoegren's
             syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis,
             seronegative spondyloarthropathy

          -  History of intra-articular injection in the last 3 months.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Novel Imaging of the Eustachian Tube; Patient Study (NCT02282540)

Eligibility criteria:
Inclusion Criteria:

        Patients > 18 years old Referred to ENT clinic at Rikshospitalet for evaluation and
        treatment of OME, tympanic membrane peroration or tympanic membrane retraction Dysfunction
        of the ET is suspected by the ENT surgeon The patient is a candidate for balloon dilation
        of the ET

        Exclusion Criteria:

        Previous serious allergic reaction to iodine based contrast medium Increased risk of
        bleeding Serious heart disease Diabetes I Previous ENT-surgery (t-tubes excluded) Middle
        ear disease, which requires other type of treatment Chronic rhino sinusitis or nasal
        polyposis Pregnancy
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Entailment
Clinical trial: Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy (NCT03868579)

Eligibility criteria:
Inclusion Criteria:

          -  Patients who will undergo pleuroscopy with biopsy

        Exclusion Criteria:

          -  Patients with known malignant pleural effusion

          -  Inability or unwillingness to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? Entailment
Clinical trial: Steam Inhalations in COVID-19 Patients (NCT04743349)

Eligibility criteria:
Inclusion Criteria:

          -  Adults with a SARS-CoV-2 positive molecular swab carried out in the previous 48 hours
             before the enrollement

          -  Adults with mild infection

          -  Adults with symptoms such as fever above 37 ° C, feeling bad, cold symptoms (cough,
             pharyngodynia, nasal congestion), headache, myalgia, diarrhea, anosmia, dysgeusia

          -  Adults without the above symptoms

        Exclusion Criteria:

          -  Adults with dyspnea and/or dehydration and/or alterations in consciousness and/or
             sepsis.

          -  Subjects with severe asthma

          -  Subjects and with contraindications to treatment with steam inhalations

          -  Multi-allergic subjects

          -  Subjects unable to complete the protocol
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: International PMS Study - KOGENATE Bayer (NCT00864552)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with severe haemophilia A (<2% FVIII baseline plasma levels) treated with
             KOGENATE Bayer as their only source of recombinant FVIII

        Exclusion Criteria:

          -  Exclusion criteria must be read in conjunction with the product information (SmPC)
Male
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Applying Long-term Follow-up to Improve Patient Selection in Laparoscopic Anti-reflux Surgery (NCT03959020)

Eligibility criteria:
Inclusion Criteria:

          -  Having undergone any anti-reflux surgery at Department of Surgery, Kolding Hospital, a
             part of Hospital Lillebaelt, Denmark from January 1, 2002 to December 31, 2013

        Exclusion Criteria:

          -  None
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: Neuromodulation in Lateral Elbow Pain (NCT03433716)

Eligibility criteria:
Inclusion Criteria:

          -  Presence of pain in the elbow region at least for three months

          -  Flares with activity

          -  Tenderness at or within 2cm of the lateral humeral epicondyle on resisted extension of
             the wrist and/or the third finger.

        Exclusion Criteria:

          -  Participants who had constant or radicular pain

          -  Any previous surgery or acute trauma in the upper extremity.

          -  Elbow deformity

          -  Bilateral symptoms

          -  Clinical or electrophysiological findings referable to peripheral nerve (ulnar and
             median) disease and
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Insulin Response to the Gut Hormone GIP After Near-normalisation of Plasma Glucose in Patients With Type 2 Diabetes (NCT04228484)

Eligibility criteria:
Inclusion Criteria:

          1. Type 2 diabetes

          2. Metformin treatment

          3. Haemoglobin A1c (HbA1c) I. > 59 mmol/mol in case the diabetes treatment is only
             metformin II. 59-75 mmol/mol in case the diabetes treatment is metformin and add-on
             therapy

          4. Body Mass Index (BMI) > 25 kg/m2

          5. Age > 18 years

          6. Caucasian

          7. Normal haemoglobin levels

        Exclusion Criteria:

          1. Treatment with insulin or GLP-1-receptor agonist

          2. Any treatment that cannot be paused for 12 hours

          3. Diabetes duration more than 20 years

          4. Weekly alcohol intake of more than 14 units for men or 7 units for women of alcohol
             (of 12 g) or narcotics abuse

          5. Liver disease

          6. Kidney disease (estimated glomerular filtration rate, eGFR < 60 ml/min/1,73 m2)

          7. Unusual dietary preferences or planned weight loss within the duration of the study

          8. Any other condition that in the opinion of the responsible investigators is
             disqualifying.

          9. For women I. Current or planned pregnancy for the duration of the study II. Positive
             pregnancy test at the screening or any of the experimental days III. Women who are
             currently breastfeeding
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Entailment
Clinical trial: Tamsulosin to Prevent Postoperative Urinary Retention in Laparoscopic Inguinal Hernia Repair (NCT04434378)

Eligibility criteria:
Inclusion Criteria:

          1. All patients undergoing elective laparoscopic inguinal hernia repair, unilateral or
             bilateral.

          2. ≥18 years of age.

          3. Patients must leave the operating room without at indwelling urinary catheter.

        Exclusion Criteria:

          1. History of neurogenic bladder requiring routine intermittent catheterization

          2. Emergent laparoscopic hernia repair.

          3. Elective laparoscopic hernia repair in conjuncture with an additional operation (e.g.
             nephrectomy, pelvic surgery) that requires the patient to have a planned, indwelling
             urinary catheter in the postoperative period.

          4. Pregnant women.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment