araag2/NLI4PR huggingface dataset:
Clinical trial: Assessment of the ACE Program for Rehabilitation in Hearing Loss (NCT01846676)

Eligibility criteria:
Inclusion Criteria:

          -  Bilateral hearing loss equal or higher than 40 decibels

          -  Age 65 years old or more

          -  Agree to be included in the study

          -  Have a relative to go to the intervention with the subject

        Exclusion Criteria:

          -  Severe organic brain impairment

          -  Physical or mental incapacity to understand the study questionnaires

          -  Structural pathology of the ear that produces hearing loss as chronic otitis media,
             ear canal tumor, or tumor of the cerebellopontine angle
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Contradiction
Clinical trial: Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy (NCT03043209)

Eligibility criteria:
Inclusion Criteria:

          -  Patient is 18 years and older has a clinical diagnosis of hypertrophic cardiomyopathy.

          -  Patient scheduled for clinically-indicated myomectomy.

          -  Patient has a negative family history of hypertrophic cardiomyopathy

          -  Patient is willing to receive results of secondary variant screen

        Exclusion Criteria:

          -  Pregnant

          -  Inability to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: To Study the Characteristics of Different Types of Vertigo in Patients Attending the Ear Nose & Throat (ENT) Clinics. (NCT02213120)

Eligibility criteria:
Inclusion Criteria:

          -  Male or female patients 18 years of age and older

          -  Patients with vestibular vertigo of known or unknown origin

          -  Patients who are willing and able to provide written informed consent

        Exclusion Criteria:

          -  Patients with any condition which, in the opinion of the investigator, makes the
             patient unsuitable for inclusion based on clinical judgment

          -  Patient with psychiatric disorders, significant neurological disorder or spinal cord
             damage that would make the evaluation difficult for the investigator

          -  Patients who are not willing to give informed consent

          -  Patients with a known history of hypersensitivity to betahistine

          -  Patients with a history of pheochromocytoma
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient description (patient's own words): The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of a 4-phasic Oral Contraceptive for the Treatment of Heavy Menstrual Bleeding (NCT01638923)

Eligibility criteria:
Inclusion Criteria:

          -  Women 18 years or older in generally good health with a diagnosis of heavy menstrual
             bleeding without organic pathology, requesting contraception

          -  Willingness to use barrier contraception (e.g., condoms) from screening to study
             completion

          -  Willingness to use and collect sanitary protection (pads and tampons) provided by the
             sponsor and compatible with the alkaline hematin test throughout study completion

        Exclusion Criteria:

          -  Current diagnosis of organic uterine bleeding

          -  History of endometrial ablation, or dilatation and curettage within 2 months of Visit
             1.

          -  Clinically significant pelvic findings (whether or not confirmed by transvaginal
             ultrasound [TVU]).

          -  Clinically significant abnormal results of breast examination (breast palpation).

          -  Positive pregnancy test at Visit 1

          -  Less than three months since delivery, abortion, or lactation before to start Visit 1

          -  Other contraceptive methods

          -  Any disease or condition that may worsen under hormonal treatment

          -  Smokers over the age of 35

          -  Body mass index >32
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy (NCT02470117)

Eligibility criteria:
Inclusion Criteria:

          -  Pregnant women gestational age less than 36 weeks with heartburn

        Exclusion Criteria:

          -  Having medical disease that contraindicated to use study drug

          -  Allergic to alginate-based reflux suppressant and magnesium-aluminium antacid gel
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effect of Food Taste, Temperature, and Viscosity on Swallowing Efficiency (NCT01270204)

Eligibility criteria:
Inclusion Criteria:

          -  Normal Volunteers:

               -  Older than 55 years of age

               -  No history of voice, swallowing, reflux, or progressive neurologic disease
                  affecting the swallowing mechanism.

               -  A normal self-administered dysphagia questionnaire (EAT-10 score of less than
                  three)

          -  Patients with Dysphagia

               -  Older than 55 years of age

               -  Patients with the following condition: Dysphagia, globus, gastroesophageal
                  reflux, or any other condition requiring referral for a dynamic swallowing study.

               -  Patients willing to provide written informed consent for their participation in
                  the study.

        Exclusion Criteria:

          1. Patients unable to complete the administration of the full taste and viscosity
             protocol.

          2. Patients with profound dysphagia unable to safely consume the test solutions.

          3. Patients with known sensitivities or allergies to any of the test solutions.

          4. Patients who are prisoners.

          5. Patients have a history of diabetes.

          6. Patients who are unable to follow the simple instructions to swallow the test
             solutions on instruction and answer the questionnaire.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 55 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: The Effect of Patient's Position After Intra-tympanic Injection on the Amount of Fluid in the Middle Ear (NCT04449848)

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed with Sudden Sensorineural Hearing Loss, treated using
             intra-tympanic injection of steroids to the middle ear

        Exclusion Criteria:

          -  Patients with abnormal sense of taste

          -  Middle or inner ear anomaly

          -  Eustachian tube dysfunction
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessing Use Of Mifepristone After Progestin Priming For Use As "Missed Period Pills" (NCT04676776)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18-49 years

          -  General good health

          -  Does not want to be pregnant

          -  History of regular monthly menstrual cycles (±3 days)

          -  Missed menses of 1 to 10 days as verified by report of last menstrual period

          -  Sexual activity in the past month

          -  Willing and able to sign consent forms

          -  Willing to return for a follow-up visit

          -  Willing to provide a urine sample at enrollment and at follow-up

        Exclusion Criteria:

          -  Known allergies or contraindications to mifepristone

          -  Symptoms of or risk factors for ectopic pregnancy, such as vaginal bleeding or
             spotting within the past week; unilateral pelvic pain or significant bilateral pelvic
             pain within the past week; prior ectopic pregnancy; prior permanent contraception or
             other tubal surgery

          -  Current use of an IUD, contraceptive implant or injectable
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 49 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Relationship Between Cold Water Immersion and the Progression in Gout Arthritis (NCT04587544)

Eligibility criteria:
Inclusion Criteria:

          -  People with gouty arthritis in the knee or ankle or metatarsophalangeal or
             metacarpophalangeal or olecranon bursa or wrist

          -  Participants were Indonesian nationals aged ≥18 years

          -  They had visited a clinic of the Public CHS of Tomohon City

          -  They had agreed to participate in the study.

        Exclusion Criteria:

          -  Participants who self-reported the presence of other types of inflammatory arthritis,
             including RA or spondyloarthritis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? Entailment
Clinical trial: Repair of Groin Hernias After Abdominal Prostatectomy With Robotic TAPP (NCT04718597)

Eligibility criteria:
Inclusion Criteria:

          -  Adult patients

          -  Underwent uni-or bilateral groin hernia repair in the period March 2015 - March 2020

          -  Groin hernia repair via robotic assisted laparoscopy or open surgery

          -  History of abdominal prostatectomy before the groin hernia repair

        Exclusion Criteria:

          -  Age below 18

          -  Groin hernia repair via conventional laparoscopy

          -  Groin hernia repair via open surgery other than Liechtenstein method

          -  Groin hernia repair without mesh placement
Male

Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Contradiction