araag2/NLI4PR huggingface dataset:
Clinical trial: Rapid HIV Testing Program in the Emergency Department (NCT00548041)

Eligibility criteria:
Inclusion Criteria:

        One of the following conditions:

          -  Sexually transmitted disease evaluation or prior history of sexually transmitted
             disease

          -  Pregnancy

          -  Clinical condition that suggests possible immunodeficiency

          -  History of illicit drug use

          -  History of chronic viral hepatitis

          -  Patients with unexplained pneumonia or recurrent pneumonia

          -  Male patients who have a history of sex with men

          -  Abdominal pain in a sexually active woman or urethritis in a man

          -  Trauma.

          -  Age 18 years old or older.

        Exclusion Criteria:

          -  Age less than 18 years.

          -  None of the above conditions.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Study on the Correlation of Free Vitamin d With BMD and Fracture (NCT03605173)

Eligibility criteria:
Inclusion Criteria:

          -  patients with a diagnosis of osteoporosis and with or without fracture

          -  post- menopausal women

          -  age > 48 years

        Exclusion Criteria:

          -  vitamin D supplementation in recent 6 months

          -  patients on steroid

          -  age < 48 years

          -  patients with chronic diseases such as liver cirrhosis, renal failure, hypertension,
             hyperparathyroidism
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 48 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Targeted Next Generation Sequencing and Intellectual Disability (NCT02889068)

Eligibility criteria:
Inclusion Criteria:

          -  Moderate or severe intellectual disability

          -  Availability of patient and parent DNA

          -  No etiologic diagnosis with standard approaches: negative fragile X, normal pangenomic
             180K and 1M array-CGH

          -  Informed consent of person having parental authority

        Exclusion Criteria:

          -  Non availability of parent DNA

          -  Patient lost to follow-up
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 15-year-old boy with mild intellectual disability is brought to the office by his parents for a routine physical examination.  The boy is going to a school for students with learning disabilities.  The patient was adopted, and his immunizations are up to date.  Review of the patient's medical records is notable for cytogenetic studies that showed a small gap near the tip of the long arm of the X chromosome, which is consistent with fragile X syndrome, an X-linked disorder. The defect is an unstable expansion of trinucleotide repeats (CGG) in the fragile X mental retardation 1 (FMR1) gene, located on the long arm of the X chromosome. He is not using any medications and vital signs are within normal levels. His blood chemistry analysis as bellow:
Blood Chemistry Value      Normal Range     Patient Value
Glucose                    90-120 mg/dl     95 mg/dl
BUN (Blood Urea Nitrogen)  7-24 mg/dl       10 mg/dl
Creatinine                 0.7-1.4 mg/dl    0.8 mg/dl
Calcium                    8.5-10.5 mg/dl   9 mg/dl
Sodium                     134-143 mEq/L    135 mEq/L
Potassium                  3.5-4.5 mEq/L    3.7 mEq/L
Chloride                   95-108 mEq/L     98 mEq/L
CO2                        20-30 mEq/L      25 mEq/L
Blood pH                   7.38-7.42        7. 39

Patient description (patient's own words): My husband and I brought our 15-year-old son to the clinic for his routine exam. My son is going to school for special needs students. We adopted him a few years ago. His vaccinations are up to date. He already passed some chromosome testing and they found that he has a fragile X syndrome. The doctor told us that it comes from repeats in the fragile X chromosome. My son is not using any medication and his blood pressure temperature and breathing were normal during the exam. He also did a blood test. The results came back and showed that his blood sugar urea creatinine calcium sodium potassium chloride CO2 and blood pH were all within the normal range.

Does the patient match the trial criteria? Contradiction
Clinical trial: Waist Circumference Versus Body Mass Index to Predict Severity of Gastroesophageal Reflux Disease (NCT00698178)

Eligibility criteria:
Inclusion Criteria:

          -  age more than 20 years old and less than 70 years old

          -  typical gastroesophageal reflux symptoms (heart burn and acid reflux)

          -  outpatient

          -  complete upper gastrointestinal endoscopy

        Exclusion Criteria:

          -  age less than 20 years or more than 70 years old

          -  receive medication for reflux disease (including proton pump inhibitor, histamine type
             2 receptor blocker, prokinetic agents) in previous one month

          -  pregnant women

          -  history of abdominal surgery

          -  severe comorbidity with cirrhosis, end-stage renal disease, heart failure

          -  no written informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Contradiction
Clinical trial: Dry Needling for Patients With Back Pain (NCT03586778)

Eligibility criteria:
Inclusion Criteria:

          -  Primary complaint of back pain

          -  Modified Oswestry Disability Index > 10 points=20%

        Exclusion Criteria:

          -  Red flags noted in the patient's Low Back Medical Screening (i.e. tumor, fracture,
             metabolic diseases, Rheumatoid Arthritis, prolonged history of steroid use, pregnancy,
             ankylosing spondylitis, cauda equina).

          -  Use of high doses of blood thinners

          -  Evidence of central nervous system involvement, to include hyperreflexia, sensory
             disturbances in the lower extremity, intrinsic muscle wasting of the hands,
             unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of
             the face, altered taste, the presence of pathological reflexes (i.e. positive
             Hoffman's and/or Babinski reflexes), etc.

          -  Workers compensation or pending legal action regarding their back pain

          -  Insufficient English language skills to complete all questionnaires

          -  Inability to comply with treatment and follow-up schedule
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Observational Study in Diagnosed Patients COVID-19, Supported on an Outpatient Basis. (COVID-PSL) (NCT04402905)

Eligibility criteria:
Inclusion Criteria:

          -  Age >18 years

          -  COVID PCR + patient: Patient screened positive by PCR on nasopharyngeal swab

          -  or COVID-like patient: Patient not screened, but considered COVID + because contact
             with a COVID PCR + person, and presenting symptoms suggestive of COVID-19 among:

          -  Influenza-like illness (fever, body aches, arthralgia, etc.)

          -  Respiratory form: dyspnea, cough, rhinitis

          -  Gastrointestinal form: diarrhea, nausea, vomiting

          -  Anosmia and / or ageusia

          -  or patient COVID PCR-: If patient tested negative by PCR on nasopharyngeal swab, but
             showing signs suggestive of COVID-19.

        Exclusion Criteria:

          -  Patient objecting to the use of their data for research purposes

          -  Patient under justice or deprived of liberty.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Assessment of Visual Function in Ophthalmic Disorders Using Virtual Visual Field Analysis (NCT04110015)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with retina, glaucoma and neuroophthalmic disorders

          -  Patients with normal eye exams to act as controls

          -  Must be able to comprehend instructions and perform visual fields

        Exclusion Criteria:

          -  Patients <18years old

          -  Patients unable to comprehend visual field instructions or unwilling to participate

          -  Patients lacking a complete clinical file or lacking a specific diagnosis
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effect of Neuromuscular Training on Osteoarthritis: A Comparative Prospective Randomized Study (NCT00457132)

Eligibility criteria:
Inclusion Criteria:

          -  radiographically assessed osteoarthritis of the knee graded 1 to 4 according to the
             Kellgren and Lawrence scale

          -  self reported moderate to severe level pain

        Exclusion Criteria:

          -  acute septic arthritis

          -  predisposition to a tendency to fall

          -  lack of physical or mental ability to perform or comply with the treatment procedure

          -  diabetes mellitus

          -  history of pathological osteoporotic fracture
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Motivators and Barriers to Physical Activity in Knee Osteoarthritis Patients: a Qualitative Study (NCT02777684)

Eligibility criteria:
Inclusion Criteria:

          -  symptomatic knee osteoarthritis

        Exclusion Criteria:

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: Isolation and Characterization of the Extracellular Vesicles Secreted by the Human Endometrium (NCT02797834)

Eligibility criteria:
Inclusion Criteria:

          -  Healthy women in natural cycles.

          -  Age: 18 to 35 years (both included).

          -  Normal karyotype.

          -  Negative serological results for HIV, HBV, HBC, RPR.

          -  BMI: 18-30 Kg/m2 (both included).

          -  Regular menstrual cycle (3-4/28-30 days).

        Exclusion Criteria:

          -  Patients who had carried a IUD device in the previous 3 months.

          -  Patients who had taken hormonal contraceptives in the previous 2 months.

          -  Adnexal or uterine pathologies.

          -  Polycystic ovary syndrome.

          -  Patients suffering from serious or uncontrolled bacterial, fungal or viral infectious
             diseases that could potentially interfere with the participation of the patient or
             with the results of the study (evaluated by the principal researcher of the research
             team).

          -  Any unstable disease or medical condition that could interfere with the study or put
             in risk the health of the patient (evaluated by the principal researcher of the
             research team).
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction