araag2/NLI4PR huggingface dataset:
Clinical trial: UTHealth Turner Syndrome Research Registry (NCT03185702)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of Turner Syndrome

        Exclusion Criteria:

          -  Diagnosis excluding Turner Syndrome
Female




Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Patient Follow-up After Consultation in Emergency Department (NCT03117179)

Eligibility criteria:
Inclusion Criteria:

          -  Major patient not benefiting from any legal protection measures.

          -  Speaking French.

          -  Outgoing after having received a consultation in a hospital emergency department.

          -  Accepting to participate in the study after being informed of the protocol.

          -  Having the possibility to be reached by telephone on J7.

        Exclusion Criteria:

          -  Patient with a pathology that does not allow him or her to understand instructions or
             express themselves.

          -  Patient under tutelage or curatorship or deprived of all freedom.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: Rebamipide AND Sjögren Syndrome (NCT01759108)

Eligibility criteria:
Inclusion Criteria:

          -  SS patients with dry mouth symptoms

        Exclusion Criteria:

          -  Patients with dry mouth due to other conditions
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? Entailment
Clinical trial: Acupuncture Treatment for Improving Alzheimer's Dementia (NCT04064021)

Eligibility criteria:
Inclusion Criteria:

          -  Mild to moderate AD

        Exclusion Criteria:

          -  Severe AD
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 60 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Nasal Findings in Reactive Airway Diseases (NCT03131323)

Eligibility criteria:
Inclusion Criteria:

          -  All children having chest wheezes, aged from two years to eighteen years, attending
             emergency unit of Assiut University Pediatric Hospital, during the period 1⁄6∕2017 to
             1∕6⁄2018. They will be examined in Otolaryngology Department, Assiut University
             Hospital

        Exclusion Criteria:

          -  Refusal of endoscopic nasal examination by care givers.and patients with definite
             diagnosis of wheeze (bronchiolitis,pneumonia)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 18 Years

Patient description (medical language): A 7-year-old girl is brought to the emergency department by her parents for generalized rash.  The mother reports that she was playing outside wearing a skirt and felt a sharp pain in her arm while seating on a mat, plying with her doll.  Her mother suspects that something had stung her.   The patient's blood pressure is 75/55 mm Hg and her heart rate is 122/min.  Physical examination shows erythematous, raised plaques over the trunk, extremities, and face.  Lung auscultation reveals bilateral expiratory wheezes.

Patient description (patient's own words): I just brought my seven-year-old girl to the ER because she just developed a terrible rash. My little girl was playing outside and she was wearing a lovely little skirt and all of a sudden. She felt like a really sharp pain in her arm. She was sitting on a mat playing with her doll. I think that something stung her. They took her blood pressure, and it turned out to be 75 out of 55. Her heart rate was 122. Then they did a physical examination, and it showed rashes all around her trunk, extremities, and face. Her breath test revealed some high-pitched breathing.

Does the patient match the trial criteria? Entailment
Clinical trial: Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes (NCT02703246)

Eligibility criteria:
Inclusion Criteria:

          -  Hysterectomy planned for a benign gynecologic reason

          -  Patient is scheduled to have surgery with one of the minimally invasive gynecologic
             surgeons at George Washington University Hospital. (Dr. Moawad, Dr. Marfori, or Dr.
             Vargas)

          -  Patient is planned for a robotic assisted total laparoscopic hysterectomy (RA-TLH) or
             a total laparoscopic hysterectomy (TLH)

          -  Patient is capable of informed consent

          -  Patient must be between 18 and 65 years of age

          -  Uterus greater than 12 centimeters in height and 4 centimeters in width or 12 weeks in
             size

        Exclusion Criteria:

          -  Hysterectomy is indicated for malignancy

          -  Procedure is anything other than RA-TLH or TLH

          -  Surgeon is not one of hte minimally invasive surgeons at GWUH

          -  Surgery is scheduled for a hospital other than GWUH

          -  Patient does not meet the age requirements.

          -  Patient is not capable of informed consent

          -  Uterus is less than 12 cm in heightand 4 cm in width
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Molecular and Clinical Profile of Von Willebrand Disease in Spain (NCT02869074)

Eligibility criteria:
Inclusion Criteria: One or more of the following:

          1. VWF ≤ 30 IU/d, in 2 or more occasions.

          2. Presence of multimeric abnormalities.

          3. If isolated FVIII deficiency demonstration of decreased FVIII binding.

          4. Presence of some VWF mutation.

          5. ↑ RIPA at low concentrations of ristocetin.

        Exclusion Criteria:

          1. Presence of any data suggesting AVWS.

          2. Absence of a signed patient informed consent
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 2 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Ultrasound Estimation of Pleural Effusion in the Sitting Patients (NCT02809872)

Eligibility criteria:
Inclusion Criteria:

          -  Monolateral or Bilateral Pleural Effusion (any cause)

          -  Able to achieve a sitting position

          -  Chest CT scan within 24 hours available

          -  Informed consent available

        Exclusion Criteria:

          -  No informed consent available

          -  Age under 18

          -  No recent Chest CT scan available

          -  Unable to keep the sitting position
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Cytokine Storm Among Bangladeshi Patients With COVID-19 (NCT04598334)

Eligibility criteria:
Inclusion Criteria:

          1. Adults aged ≥18 years,

          2. Informed consent obtained for participation,

          3. A mild, moderate or severe (±critical cases) RT-PCR confirmed COVID-19 cases,

          4. RT-PCR negative healthy volunteers.

        Exclusion Criteria:
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Treatment of Lateral Elbow Tendinopathy (NCT02521298)

Eligibility criteria:
Inclusion Criteria:

          1. Pain around the lateral part of the elbow joint for more than 4 weeks.

          2. Pain on palpation of the proximal part of the common extensor tendon.

          3. Pain reproduced with resisted dorsiflexion of the wrist.

          4. Dash score > 30.

          5. Ultrasonographic appearance consistent with lateral elbow tendinopathy (irregular
             appearance of the tendon, hypo-/hyper-echoic changes, pathological doppler signal,
             increased tendon thickness).

        Exclusion Criteria:

          -  American Society of Anesthesiologists (ASA) > 2 (mild systemic disease).

          -  Patients with symptoms consistent with differential diagnoses such as:

               -  referred pain,

               -  radiohumeral synovitis and bursitis,

               -  posterior interosseous nerve entrapment (radial tunnel syndrome),

               -  osteoarthritis of the elbow, and

               -  prior injections or acupuncture around the elbow joint within the last 6 months
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Entailment
Clinical trial: Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma (NCT00003937)

Eligibility criteria:
DISEASE CHARACTERISTICS: Histologically proven newly diagnosed moderate or high grade
        osteosarcoma without metastases No prior treatment, including complete resection No
        parosteal or periosteal sarcoma No osteosarcoma associated with Paget's disease No
        nonresectable tumors or tumors that may result in marginal or interlesion resection Must be
        enrolled on protocol POG-9851

        PATIENT CHARACTERISTICS: Age: 30 and under Performance status: ECOG 0-2 Life expectancy:
        Not specified Hematopoietic: Absolute neutrophil count at least 1,000/mm3 Platelet count at
        least 100,000/mm3 Hepatic: Bilirubin no greater than 1.5 times normal SGOT no greater than
        3 times normal Renal: Creatinine normal Phosphate at least 3.0 mg/dL without
        supplementation Cardiovascular: Shortening fraction at least 28% by echocardiogram If
        echocardiogram unsatisfactory, must have ejection fraction at least 50% No history of
        pericarditis or myocarditis No symptomatic arrhythmia or symptomatic cardiac conduction
        disturbances

        PRIOR CONCURRENT THERAPY: See Disease Characteristics Biologic therapy: Not specified
        Chemotherapy: No prior chemotherapy Endocrine therapy: Not specified Radiotherapy: No prior
        radiotherapy Surgery: See Disease Characteristics
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.

Subject must be at most 30 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment