araag2/NLI4PR huggingface dataset:
Clinical trial: Validation of King's Sarcoidosis Questionnaire in a Danish Population (NCT04388085)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosed with sarcoidosis

          -  Signed informed consent

        Exclusion Criteria:

          -  Inability or unwillingness to adhere to the study

          -  Inability to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy of Eccentric Resistance Training in Persons With Knee Osteoarthritis (NCT02350387)

Eligibility criteria:
Inclusion Criteria:

        Individuals will be included in the study if they are:

          -  at least 55 years old,

          -  cognitively able to understand directions,

          -  able to ambulate at least 50 feet without stopping,

          -  are currently experiencing knee pain and

          -  meet at least 3 out of 6 criteria of the European League Against Rheumatism (EULAR)
             criteria for knee osteoarthritis diagnosis.

        Exclusion Criteria:

        Individuals will be excluded from the study if they have:

          -  a diagnosed medical condition that would limit physical ability, including acute or
             active fractures, myocardial infarctions, stroke,

          -  a traumatic brain injury within the last 6 months, or

          -  joint replacement within the last 12 months. Individuals with chronic neurological
             disorders limiting motion or present with any known contraindication for balance
             training will also be excluded from the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Endodrill vs. Conventional Biopsy. Evaluation of Diagnostic Capacity in Diffuse Gastric Cancer (NCT02594943)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with suspected or with an established diagnosis of diffuse gastric cancer who
             are capable of stating a formal consent to participate in the study.

        Exclusion Criteria:

          -  Mental illness

          -  Extreme co-morbidity (ASA>3)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Evaluation of Surgical Treatment of Terrible Triade Injury of the Elbow Joint (NCT04578977)

Eligibility criteria:
Inclusion Criteria:

          -  1.skeletally mature patients (over 17 years old) including both sexes. 2.Acute
             fractures within 3 weeks of injury. 3.Isolated & closed fractures . 4.polytrauma
             trauma patients with no other injuries in the same limb.

        Exclusion Criteria:

          -  1. pathological fracture of proximal radius and ulna. 2. deteriorateed general health.
             3. previous history of dysfunction with the affected elbow.
No condition on gender to be admitted to the trial.

Subject must be at least 17 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Entailment
Clinical trial: Open-Label Study of Diclofenac Capsules to Treat Osteoarthritis Pain (NCT01510912)

Eligibility criteria:
Inclusion Criteria:

          -  Male or female ≥ [greater than or equal to] 40 years of age

          -  If a participant in the previous DIC3-08-05 study, completed the study and did not
             discontinue for lack of efficacy or safety

          -  Has a diagnosis of OA of the hip or knee with ongoing knee and/or articular hip pain

          -  Is a current chronic user of nonsteroidal anti-inflammatory drugs (NSAIDs) and/or
             acetaminophen for his/her OA pain and is anticipated to benefit from continuous
             treatment with therapeutic doses of NSAIDs. A current chronic user is defined as a
             subject who has used these treatments for ≥ [greater than or equal to] 20 days of the
             last 30 days before screening

        Exclusion Criteria:

          -  Has a known history of allergic reaction or clinically significant intolerance to
             acetaminophen, aspirin, or any nonsteroid anti-inflammatory drugs (NSAIDs), including
             diclofenac

          -  Requires chronic use of opioid or opioid combination products to control OA pain of
             the knee or hip

          -  Has any clinically significant unstable cardiac, respiratory, neurological,
             immunological, hematological, or renal disease

          -  Has significant difficulties swallowing capsules or is unable to tolerate oral
             medication
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: Phase 2 Study for the Treatment of Superficial Lipomas (NCT00608842)

Eligibility criteria:
Inclusion Criteria:

          -  One or more lipomas, based on clinical and histological diagnosis, which are
             accessible for treatment and assessment, are quantifiable along at least 2
             perpendicular diameters, and have the following characteristics:

               -  History of slow growth followed by dormancy, and stable for at least 6 months

               -  Greatest length multiplied by greatest perpendicular width between 1 and 16 cm²,
                  inclusive

               -  Discrete, oval to rounded in shape, not hard or attached to underlying tissue

               -  Without changes in overlying skin (ie, inflammation, pain or tenderness,
                  hyperpigmentation)

               -  Located on the trunk, arms, legs, or neck

          -  Signed informed consent.

        Exclusion Criteria:

          -  Absence of significant medical conditions that could affect safety

          -  History of surgical or deoxycholate treatment for lipomas

          -  Treatment with an investigational agent within 30 days before ATX-101 treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair (NCT01323361)

Eligibility criteria:
Inclusion Criteria:

          -  Adults admitted for ventral or incisional hernia repair

        Exclusion Criteria:

          -  Loss-of-domain

          -  ASA above III

          -  Liver failure

          -  Abnormal CA-125 prior to surgery
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Objective and Perceived Quality Study in Patients Undergoing Elective Groin Hernia Surgery (NCT03860285)

Eligibility criteria:
Inclusion Criteria:

          -  Patients entering surgical waiting list during a year (from March 1st, 2018, to
             February 28th, 2019).

          -  Elective surgery.

        Exclusion Criteria:

          -  Age below 16.

          -  Mental diseases.

          -  Patients not capable of understanding the study.

          -  Patients that reject entering the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 16 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis) (NCT03718637)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of lateral epicondylitis (tennis elbow) that has failed conservative
             treatment (Physical therapy, activity change, anti-inflammatory treatment.

        Exclusion Criteria:

          -  Previous surgery on the currently-affected elbow.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Contradiction
Clinical trial: Observational Study of Azilsartan/Chlorthalidone and Irbesartan/Hydrochlorothiazide in Hypertension and Obesity. (NCT03006796)

Eligibility criteria:
Inclusion Criteria:

          1. male and female 35-55 year old,

          2. diagnosis of I-II grade essential AH,

          3. patients with obesity (BMI ≥ 30 kg/m²),

          4. patients with untreated AH (office SBP ≥ 140 mmHg, DBP ≥ 90 mmHg, no previous
             antihypertensive therapy),

          5. patients with poorly controlled AH (office SBP ≥ 140 mmHg, DBP ≥ 90 mmHg on previous
             antihypertensive therapy),

          6. written informed consent form (ICF).

        Exclusion Criteria:

          1. patients with symptomatic organ damage (myocardial infarction, stroke, angina
             pectoris, chronic kidney disease stage ≥ 4, diabetes),

          2. patients with intolerance of ARB, thiazide diuretics,

          3. secondary AH,

          4. patients with contraindication to study drugs in accordance with Russian instruction,

          5. patients currently enrolled in other clinical trials.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 35 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Contradiction