araag2/NLI4PR huggingface dataset:
Clinical trial: Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery (NCT03524807)

Eligibility criteria:
Inclusion Criteria:

        .After electrocision of intrauterine adhesions;

        .Or after common gynecologic laparoscopic surgery，patients occurred muscle pain or patients
        occurred urinary retention.

        Exclusion Criteria:

          -  Pregnancy;

          -  Suspected acute inflammation of the genitourinary system;

          -  Postoperative persistent vaginal bleeding;

          -  Patients have vaginal stenosis;

          -  Patients have implantation of a pacemaker with a cardiac pacemaker;

          -  Patients have a malignant pelvic organ tumor; .Patients have nervous system disease
             (dementia or unstable seizures),who cannot actively cooperate with the treatment.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Corticosteroid Injection for Common Upper Extremity Problems (NCT00438672)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 to 64 years

          -  onset of pain within the past 6 months

          -  willing to try a steroid injection in the elbow

        Exclusion Criteria:

          -  systemic inflammatory diseases (e.g., rheumatoid arthritis)

          -  pregnancy

          -  prior steroid injection, iontophoresis treatments with corticosteroids, or surgery for
             their pain

          -  history of adverse reaction to lidocaine
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Contradiction
Clinical trial: Motor-related Cortical Potential in Patients With Essential Tremor (NCT01250067)

Eligibility criteria:
Inclusion Criteria:

          -  Bilateral postural tremor with or without kinetic tremor involving hands or forearms,
             which is visible and persistent, and long-standing in duration (>5 years). Tremor
             involving body parts other than upper limbs may be present, the tremor may be
             asymmetrical, amplitude may fluctuate, and the tremor may or may not produce
             disability.

        Exclusion Criteria:

          -  Neurological signs, except for Froment's sign

          -  Causes of enhanced physiologic tremor

          -  Concurrent or recent exposure to tremorgenic drugs

          -  Direct or indirect trauma to the central and peripheral nervous system

          -  Historical or clinical evidence of psychogenic origins of tremor

          -  Convincing evidence of sudden onset or evidence of stepwise deterioration
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: Mirror Box Therapy as a Treatment Option for Functional Movement Disorders (NCT03660098)

Eligibility criteria:
Inclusion Criteria:

          1. Patients diagnosed with functional movement disorder by a fellowship trained movement
             disorders neurologist, presenting predominantly with unilateral or asymmetrical
             bilateral involuntary movement in the upper extremity

          2. In patients with bilateral involuntary movements, the symptoms in one arm must be
             minimal

        Exclusion Criteria:

          1. Patients with moderate to severe involuntary movement in both arms

          2. Significant cognitive impairment that prevents proper informed consent

          3. Severe involuntary movement that interferes with the use of the apparatus

          4. Patients with hemiparesis or the loss of one arm due to various reasons (e.g.
             amputations, birth defects, etc.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With Osteoarthritis (NCT00236366)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with osteoarthritis (OA) of the hip or the knee (as defined by the American
             College of Rheumatology) and radiological evidence of OA from the target joint

          -  patients must be in need of and waiting for hip or knee replacement

          -  patients with chronic pain for longer than 3 months for >=20 days/month

          -  patients with moderate to severe OA pain of the target joint (VAS score >=50 on a
             scale of 0-100), whose pain was not adequately controlled with weak opioids, with or
             without non-opioid pain medication

          -  women must be postmenopausal or using adequate contraception, have a negative
             pregnancy test at study initiation, and not be breastfeeding.

        Exclusion Criteria:

          -  Patients who had previously failed fentanyl therapy or had discontinued treatment due
             to adverse events

          -  known allergy or hypersensitivity to fentanyl or to the adhesives

          -  patients being treated for depression or epilepsy

          -  patients who received sedative hypnotics, anaesthetics and/or muscle relaxants in the
             week preceding the Run-In Period

          -  patients experiencing another type of continuous pain that stands out in comparison
             with OA pain

          -  patients with major trauma to the target joints, infection in these joints, or
             irreversible damage to these joints during the 6 months before the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 41 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: The Effect of Low Electrical Current on Testicular Spermatocyte Count (NCT02617173)

Eligibility criteria:
Inclusion Criteria:

          -  Men with primary infertility defined as a state of Azoospermia.

          -  Men with pathological sperm tests indices as defined by the WHO.

        Exclusion Criteria:

          -  Men with genetic syndromes, and states of Azoospermia secondary to chemotherapy, bone
             marrow transplantation or radiation.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study (NCT02635022)

Eligibility criteria:
Inclusion Criteria:

          -  Age >=50 and one of the below

          -  New hip fracture in orthopedic ward

          -  Newly identified radiographic vertebral fractures from plan films in geriatric ward or
             clinical vertebral fractures in outpatient clinics

          -  Newly prescribed with AOMs

          -  Recent change of AOMs

          -  Poor adherence to AOMs

          -  Participating physicians feel that the service will benefit the patient in overall
             osteoporosis and medication managements.

        Exclusion Criteria:

          -  Life expectancy less than 2 years or can't be assessed for communication problems

          -  Atypical fractures

          -  Patient in other medication clinical trials

          -  Unwilling to accept the assessment and treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea (NCT01927432)

Eligibility criteria:
Inclusion Criteria:

          -  Between 18 and 35 years

          -  BMI ≥ 18 kg/m2

          -  If ≥ 21 years old, must have had healthy pelvic exam w/in past 2 years

        Either:

          -  Regular menstrual cycles (21-35 days);

          -  Irregular menstrual cycles (>36 days) with or without a previous diagnosis of PCOS
             from a primary care provider

        Exclusion Criteria:

          -  Current use of medication(s) known or suspected to interfere with reproductive
             function (eg. oral contraceptives) or insulin sensitivity

          -  Pregnant or breastfeeding

          -  Not otherwise healthy
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Osteoarthritis Topical Treatment (NCT01496326)

Eligibility criteria:
Main Inclusion Criteria:

          -  Male or female patients aged at least 40 years.

          -  Primary osteoarthritis in a single knee joint, grade II/III based on the Kellgren and
             Lawrence classification system.

          -  Radiographic evidence consistent with osteoarthritis carried out within 6 months
             before screening.

          -  pain is currently not adequately controlled with a simple analgesic or an NSAID OR
             would necessitate treatment, but is not yet treated.

        Main Exclusion Criteria:

          -  Concomitant presence of another type of continuous pain that is more severe in
             intensity in comparison with the osteoarthritis target joint pain

          -  Osteoarthritis causing significant pain in any joint other than the identified knee,
             or contralateral knee (≥ 20 mm pain) as confirmed by a separate VAS at visit 1 for any
             other painful joint concerned.

          -  Female patients who are pregnant or breast-feeding.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Contradiction