araag2/NLI4PR huggingface dataset:
Clinical trial: Treatment of Missed Miscarriage With TRUCLEAR Tissue Removal System, a Feasiblity Study (NCT04512820)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with missed miscarriage up to 10 weeks from the last menstrual period

          -  Patients are able to provide written consent

          -  Patients with no underlying medical conditions

        Exclusion Criteria:

          -  Inability to consent due to cognitive or language barrier

          -  Any underlying medical condition requiring medical treatment

          -  Documented failed hysteroscopy prior to the current referral

          -  Inability to consent due to cognitive or language barrier

          -  Uterine malformations or fibroids

          -  Previous cesarean section
Female
Accepts Healthy Volunteers
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Entailment
Clinical trial: Duration of Doxycycline Treatment in EM Patients (NCT03153267)

Eligibility criteria:
Inclusion Criteria:

          -  solitary erythema migrans

        Exclusion Criteria:

          -  pregnancy or lactation

          -  immunocompromised

          -  serious adverse event to doxycycline

          -  taking antibiotic with antiborrelial activity within 10 days

          -  multiple erythema migrans or extracutaneous manifestations of lyme borreliosis
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 31-year-old woman comes to the office due to 3 days of rash on her left arm.  The lesion is mildly pruritic but not painful.  She is otherwise healthy and occasionally takes ibuprofen during the first few days of her menstrual period.  Temperature is 37 C, blood pressure is 110/75 mm Hg, and pulse is 95/min. The lesion is like a target sign known as erythema migrans. She recently went for an adventure trip in New Hampshire. The patient is diagnosed with Lyme disease.

Patient description (patient's own words): I went to the clinic because I had a rash on my left arm for three days, and the lesion started to be putrid, but it was not painful. I'm a 31-year-old healthy woman and the only medication I use is ibuprofen when I get my periods. They took my temperature, which turned out to be 37°C and took my blood pressure which was 110/75 and my pulse 95. My lesion is round like a target sign. I just came back from a New Hampshire road trip with my friends. Unfortunately, the doctor diagnosed me with Lyme disease.

Does the patient match the trial criteria? Entailment
Clinical trial: The Roles of Hilotherapy in the Management of Epistaxis and Nasal Fractures (NCT04279288)

Eligibility criteria:
Inclusion Criteria:

          -  presenting to ED with epistaxis or nasal fractures ( over 18 years)

        Exclusion Criteria:

          -  laceration around site of mask, reduced GCS, concurrent head injury, systemic shock
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS) (NCT00392756)

Eligibility criteria:
Eligibility

        Ages Eligible for Study:

          -  Adolescents (16-17yrs)

          -  Adults (18 years and older)

               -  Genders Eligible for Study:

          -  Male and Female

               -  Accepts Healthy Volunteers:

          -  No

        Criteria

        Inclusion Criteria:

          -  adolescent boys (age 16-17 years) and adult male individuals (age 18 years and older)
             with a single serum sample demonstrating low testosterone in association with low or
             inappropriately normal gonadotropin levels

          -  adolescent girls (age 16-17 years) and adult female individuals (age 18 years and
             older) with a single serum sample demonstrating low estradiol (estrogen) in
             association with low or inappropriately normal gonadotropin levels

          -  suitable male and female hypogonadotropic hypogonadal subjects

        Exclusion Criteria:

          -  no specific exclusion criteria
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.


Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Entailment
Clinical trial: An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy (NCT02310230)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects undergoing upper gastrointestinal endoscopy

        Exclusion Criteria:

          -  Patients with a history of thoracotomy with resection of lung tissue

          -  Patients with a history of severe chronic obstructive pulmonary disease (defined as an
             inability to climb a flight of stairs or FEV1/VC of less than 30% of predicted)

          -  BMI greater than 43.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy of Stem Cell Therapy in Ambulatory and Non-ambulatory Children With Duchenne Muscular Dystrophy - Phase 1-2 (NCT02484560)

Eligibility criteria:
Inclusion Criteria:

          -  Ambulatory and Non-ambulatory patients diagnosed with DMD that is proven both
             clinically and genetically and are between 5-20 years old who need partial respiratory
             support daily. Patients with less than or equal to stage 1 NIH, cardiac, liver, and
             renal function. Patients must also not present any indication of cancer, allergic
             disease, nor bleeding diathesis.

        Exclusion Criteria:

          -  Patients who require full respiratory support. Patients have stage II NIH or greater,
             cardiac, liver, and renal function. Patients present with signs of symptoms of cancer,
             allergic disease, or bleeding diathesis.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 8 Years old.
Subject must be at most 14 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? Entailment
Clinical trial: Physical Exercise for Men With Andropause (NCT03150225)

Eligibility criteria:
Inclusion Criteria:

          -  men presenting ADAM according to their responses on the Aging Male Symptoms Scale and
             testosterone levels <220 pmol/l

        Exclusion Criteria:

          -  history of neurological or musculoskeletal diseases or who have prostate cancer will
             be excluded, as also those who have been submitted toresistance and/or aerobic in the
             three months prior to data collection
Male
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 59 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Radiographic Assessment of Bone Regeneration in Alveolar Sockets With PLGA Scaffold (NCT00836797)

Eligibility criteria:
Inclusion Criteria:

          1. Under going extraction of tooth including the surgical extraction.

          2. Healthy individual with no known medical problems.

          3. Not allergic to foreign body.

          4. Extractions which are not due to periodontal causes.

        Exclusion Criteria:

          1. Bony disease.

          2. Bleeding disorder.

          3. Allergic to foreign body.

          4. Mentally retarded persons.

          5. Diabetic patient.

          6. Drug addict.

          7. Extraction due to periodontal disease.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: MEG Study of Mindfulness Based Stress Reduction (NCT00571051)

Eligibility criteria:
Inclusion Criteria:

        -

        You are eligible to participate in this study because you meet all of our selection
        criteria:

          -  You are between ages 18-50

          -  You are right-handed

          -  You are able to receive a MRI scan (you have no metal implants or other metal objects
             or medical devices that would make a MRI scan unsafe for you)

          -  You are able to follow study instructions and can read and write English

        Exclusion Criteria:

          -  You are not eligible to participate in this study if you:

               -  have any systemic musculoskeletal diseases such as rheumatoid arthritis, systemic
                  lupus, or scleroderma that would affect the function of your nervous system

               -  have any neurological conditions that might affect your hand, wrist, or arm
                  function

               -  respond to our questionnaires in a manner suggesting you may be suffering from
                  depression

               -  are pregnant or a nursing mother

               -  currently have any ongoing meditation practice, including MBSR.

               -  are unable to complete our study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: Betadine Pleurodesis Via Tunneled Pleural Catheters (NCT02975921)

Eligibility criteria:
Inclusion Criteria:

          -  Requiring Tunneled Catheter Placement for a Pleural Effusion

        Exclusion Criteria:

          -  Patient with a nonexpandable lung

          -  Non-english speaker
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Phase IV Study to Investigate the Effect of Testosterone Treatment on Paraoxonase Level in Male Patients With Hypogonadotrophic Hypogonadism (NCT01107067)

Eligibility criteria:
Inclusion Criteria:

          -  Volunteers patients with hypogonadism

        Exclusion Criteria:

          -  Coronary heart disease

          -  Other pituitary/hypothalamic disorders or other non-hypogonadism diseases

          -  None was receiving vitamins, lipid-lowering drugs, or other medications known to
             interfere with PON1 activity, lipid profile, or gonadal function
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 25 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction