araag2/NLI4PR huggingface dataset:
Clinical trial: To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility (NCT03864198)

Eligibility criteria:
Inclusion Criteria:

          -  male 18-50 years

          -  oligozoospermia: < 5 million spermatozoa/mL;

          -  asthenozoospermia: < 32% progressive motile spermatozoa;

          -  teratozoospermia: < 4% normal forms.

        Exclusion Criteria:

          -  azoospermia

          -  smoke

          -  use drugs

          -  use drugs with proven fertility toxicity

          -  exposition to any environmental or occupational toxic substances

          -  exposition to radiation or heat

          -  orchitis secondary to mumps

          -  sexually transmitted diseases

          -  history of cryptorchidism

          -  previous testicular torsion

          -  genitourinary anomalies

          -  alterations of the epididymis or deferens

          -  inguinal surgery
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Assessment of the Clinical Effectiveness of a Herbal Extract (Cretan IAMA) in Patients With Viral Respiratory Infections, Including COVID-19, in Primary Healthcare Settings, and Co-assessment of Its Prophylactic Effect in People Cohabiting With These Patients (NCT04705753)

Eligibility criteria:
Inclusion Criteria:

          -  For the patients:

               -  Any woman or man requesting a home visit and having symptoms characteristic of
                  viral infection, with initial manifestation within the previous 48-72 hrs. Such
                  symptoms may include sudden fever onset, accompanied by one or more of the
                  following symptoms: dry cough, sore throat, nasal congestion, headache,
                  musculoskeletal pain, perspiration, fatigue, malaise, blurry vision, loss of the
                  sense of smell.

          -  For the people cohabiting with patients:

               -  Any woman or man cohabiting with study patients.

        Exclusion Criteria:

          -  Children and adolescents under the age of 18 years;

          -  Pregnant women;

          -  Persons suffering from a pre-existing condition preventing them from autonomously
             providing informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: iSTAT Comparison Study, IRB3785 (NCT02208895)

Eligibility criteria:
Inclusion Criteria:

          -  any patient 18 to 99 year old with a diagnosis of pleural effusion and undergoing a
             diagnostic thoracentesis.

        Exclusion Criteria:

          -  Inability to provide informed consent by the patient or the surrogate to enroll for
             the planned study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Feasibility of a Wearable-enabled Intervention for Promoting Physical Activity in People Knee OA (NCT02313506)

Eligibility criteria:
Inclusion Criteria:

          -  Have a physician confirmed diagnosis of knee osteoarthritis OR are both 1) over 50,
             and 2) have experienced 4 weeks of pain, aching, or discomfort in or around the knee
             during the last year (equal to or more than 28 separate or consecutive days).

          -  Have no previous diagnosis of rheumatoid arthritis, psoriatic arthritis, ankylosing
             spondylitis, polymyalgia rheumatica, connective tissue diseases, fibromyalgia or gout.

          -  Have no history of using disease-modifying anti-rheumatic drugs or gout medications.

          -  Have no prior knee replacement surgery, and not on a waiting list for total knee
             replacement surgery.

          -  Have no history of acute injury to the knee in the past 6 months.

          -  Have not had surgery in the back, hip, knee, foot or ankle joints in the past 12
             months.

          -  Have an email address and daily access to a computer with internet connection.

          -  Be able to attend a 2-hour education session at the Mary Pack Arthritis Centre.

        Exclusion Criteria:

          -  Have a body mass index of equal to or greater than 40

          -  Have received a steroid injection in a knee in the last 6 months

          -  Have received a hyaluronate injection in a knee in the last 6 months

          -  Use medication that may impair activity tolerance (e.g. beta blockers)

          -  Are at risk when exercising, as identified by the Physical Activity Readiness
             Questionnaire (PAR-Q)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: Dermoscopy in Diagnosis of Pigmentary Skin Lesions (NCT03542539)

Eligibility criteria:
Inclusion Criteria:

          -  all patients attending assuit university hospital clinics complaining of pigmentary
             skin lesions

        Exclusion Criteria:

          -  no exclusion criteria
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient description (patient's own words): I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Does the patient match the trial criteria? Entailment
Clinical trial: Diagnosis of Short Stature in Children : Study of a Cohort of Small-sized Consulting Patients (NCT04754516)

Eligibility criteria:
Inclusion criteria:

        All the children who consulted for the first time because of their short stature, in
        pediatric endocrinology at the Montpellier University Hospital between January 2017 and
        December 2018

        Exclusion criteria:

        Patient already undergoing specialized medical follow-up due to his small size Major
        patient
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.

Subject must be at most 17 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Pain After Endoscopic Submucosal Dissection (NCT02254889)

Eligibility criteria:
Inclusion Criteria:

          -  patients undergoing ESD for gastric neoplasms

        Exclusion Criteria:

          -  (1) history of acid suppressive medication within 1 week prior to the procedure; (2)
             known gastrointestinal disorders, such as peptic ulcer disease, which might impact
             epigastric pain assessment; (3) current or regular use of pain medication; (4) history
             of upper gastrointestinal surgery; (5) multiple lesions requiring ESD; (6) perforation
             during ESD; and (7) significant cardiovascular, renal, hepatic, neurotic, or
             psychological disorders
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of LANCONONE in Weight-bearing Joint Pain (NCT03658369)

Eligibility criteria:
Inclusion Criteria:

          1. BMI ≥ 25 and ≤ 29.9 kg/m2.

          2. With unilateral or bilateral OA of the knee for at least greater than 3 months, as
             presented by pain in the knee at least for last 3 months.

          3. Post-menopausal females (LMP at least 12 months prior to the screening).

        Exclusion Criteria:

          1. History of osteoarthritis for more than 3 years.

          2. Systolic Blood Pressure ≥140 mm Hg and Diastolic Blood Pressure ≥ 90 mm Hg

          3. FBS>140 mg/dl.

          4. Smokers or chronic alcoholics.

          5. Participants planning to travel in the next 56 days or engage in any non-routine
             activity that is likely to strain the knees.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Chronic Oral Hydration in Patients With Recurrent Unexplained Syncope (NCT00143754)

Eligibility criteria:
Inclusion Criteria:

          -  Syncopal and/or near syncopal episodes at least twice within the prior 3 months

        Exclusion Criteria:

          -  Neurological disease

          -  Structural heart disease

          -  Metabolic and psychiatric illness
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Contradiction
Clinical trial: Efficiency and Safety of Pleural Biopsy Methods in the Diagnosis of Pleural Diseases (NCT03153501)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with pleural diseases

        Exclusion Criteria:

          -  Patients with other lung diseases
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: A Study to Evaluate the Safety and Efficacy of TS-091 in Patients With Narcolepsy (NCT03267303)

Eligibility criteria:
Inclusion Criteria:

          1. Patients diagnosed with narcolepsy type 1 or type 2 based on the International
             Classification of Sleep Disorders, third edition (ICSD-3) criteria

          2. Patients aged ≥16 to <65 years at the time of obtaining informed consent

          3. Outpatients

        Exclusion Criteria:

          1. Patients with sleep disorders other than narcolepsy (e.g., sleep apnea syndrome,
             periodic limb movement disorder)

          2. Patients with organic brain diseases (including neurodegenerative diseases or
             cerebrovascular disorders) or epilepsy

          3. Patients with obstructive respiratory diseases (bronchial asthma, emphysema)

          4. Patients with psychiatric disorders (e.g., major depressive disorder, bipolar
             disorder, schizophrenia)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.
Subject must be at most 64 Years

Patient description (medical language): A 25-year-old woman comes to the clinic with her roommate.  The roommate says that the patient has twice fallen asleep while they were talking.  The patient has regularly fallen asleep in the afternoon while reading or watching television but typically feels refreshed after a brief nap.  She also reveals that she sometimes hears a voice prior to falling asleep.  She also complains of some episodes of clumsiness that cause her to drop objects or fall. MSLT showed that the sleep latency was less than 8 min and that the patient enters rapid eye movement (REM) sleep almost immediately.

Patient description (patient's own words): I brought my roommate to the clinic because she kept falling asleep when we were having a conversation. We're both 25 and usually healthy girls. She usually takes a nap in the afternoon while reading or watching TV, but usually, she is quite energetic afterward. She told me that she sometimes hears a voice before falling asleep. How weird! And sometimes she's the clumsiest! She keeps dropping all her stuff. The doctor did a sleeping test and she found out that it takes her less than 8 min to fall asleep.

Does the patient match the trial criteria? Entailment