araag2/NLI4PR huggingface dataset:
Clinical trial: The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic (NCT02086292)

Eligibility criteria:
Inclusion Criteria:

          -  age 18 - 65

        Exclusion Criteria:

          -  regular use of analgesics

          -  known hypersensitivity of local anaesthetic

          -  renal-, heart- or liver disease

          -  known peripheral neuropathy or diabetes mellitus

          -  local infection on injection site

          -  circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient description (patient's own words): I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Does the patient match the trial criteria? Entailment
Clinical trial: Studying the Effects of 7 Days of Gonadotropin Releasing Hormone (GnRH) Treatment in Men With Hypogonadism (NCT00493961)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of idiopathic hypogonadotropic hypogonadism (IHH) or Kallmann syndrome
             (KS)Adult male 18-65 years of age

          -  Serum testosterone <100 ng/dL

        Exclusion Criteria:

          -  No specific exclusion criteria
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Pharmacokinetic Study of Oral Testosterone (T) Ester Formulations in Hypogonadal Men (NCT00695110)

Eligibility criteria:
Inclusion Criteria:

          -  Male, ages 18-68

          -  Serum total testosterone less than or equal to 275 ng/dL

        Exclusion Criteria:

          -  Significant intercurrent disease of any type, in particular, liver, kidney or heart
             disease, uncontrolled diabetes mellitus or psychiatric illness.

          -  Abnormal prostate digital rectal examination, elevated PSA, AUA symptom score of >15,
             and/or history of prostate cancer.

          -  Hematocrit of <35 or >50%

          -  BMI >36

          -  Serum transaminases > 2 times upper limit of normal or serum bilirubin > 2.0 mg/dL
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 68 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Assisted Hatching in Frozen Blastocysts (NCT03833869)

Eligibility criteria:
Inclusion Criteria:

          -  In-vitro fertilization patients at the investigators' institution, intended to undergo
             a transfer of a frozen five-day embryo (blastocyte)

          -  18 to 39 years old

          -  First to third treatment cycle

          -  Patient has previously had a maximum of four embryos transferred.

        Exclusion Criteria:

          -  Over 40 years old

          -  Congenital or acquired uterine malformations

          -  Hydrosalpinx

          -  Chronic autoimmune diseases

          -  Embryo intended to be undergo preimplantation genetic diagnosis
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 39 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Promoting Overweight Adolescents Physical Activity (NCT02295761)

Eligibility criteria:
Inclusion Criteria:

          -  13-16 years old,

          -  overweight or obese (weight for height >20% over normality)

        Exclusion Criteria:

          -  mental health problems, long term illnesses.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 13 Years old.
Subject must be at most 16 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Contradiction
Clinical trial: A Research Platform to Screen Healthcare Workers (NCT04574765)

Eligibility criteria:
Inclusion Criteria:

          -  Individuals who work within a food production, healthcare, research or clinical
             organization.

          -  Asymptomatic as per daily screening.

          -  No contraindication to performing a NP swab.

        Exclusion Criteria:

          -  Any individual with fever, respiratory or flu-like symptoms will not be eligible.
             Symptom positive individuals who were not picked up at entry screening will be
             referred to their Occupational Health. Specific symptoms include:

               -  Fever, chills or headache

               -  New or worsening cough

               -  Shortness of breath, difficulty breathing, sore throat or difficulty swallowing

               -  Runny nose or stuffy nose without another cause (e.g. allergies)

               -  Nausea/vomiting, diarrhea, stomach pain

               -  Decrease/loss of taste or smell

               -  Unexplained fatigue, malaise, muscle aches

               -  Eye pain or pink eye In addition to those symptoms listed above, individuals
                  should also be screened for symptoms as per their institutional requirements.

          -  Enrolled in a COVID-related interventional study (eg. Behavioural or drug study).
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: SpO2 System Accuracy Testing With Different Sensors (NCT01613222)

Eligibility criteria:
Inclusion Criteria:

          -  Ability to provide written informed consent or have a legally authorized
             representative provide written informed consent

          -  Subjects who are 18-55 years of age

          -  Subjects must be willing and able to comply with study procedures

          -  HbCO<3% (for smokers only)

        Exclusion Criteria:

          -  Subject or a legally authorized representative is unable to provide written inform
             consent.

          -  Subjects that are considered morbidly obese (defined as BMI > 39.5),

          -  Subjects with injuries, deformities or abnormalities that may prevent proper
             application of the device under test,

          -  Smokers with COHb levels >3% or subjects who have smoked within two (2) days. Subjects
             will be screened for COHb levels of >3% with a Masimo Radical 7 (Rainbow).

          -  Subjects with known respiratory conditions (uncontrolled asthma, head cold, flu,
             pneumonia / bronchitis, respiratory distress / respiratory or lung surgery, emphysema,
             COPD, lung disease),

          -  Subjects with known heart or cardiovascular conditions,

          -  Female subjects that are actively trying to get pregnant or are pregnant,

          -  Subjects taking blood thinners or medications with aspirin or other antiplatelet
             medication in them (applies only to arterial draw study),

          -  Subjects with Systolic blood pressure >140mmHg,

          -  Subjects with Diastolic blood pressure >100mmHg,

          -  Subjects with heart rhythms other than a normal sinus rhythm or with respiratory sinus
             arrhythmia
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: Secretory Azoospermia and FDG (Fluoro Deoxyglucose) PET-CT (NCT02043444)

Eligibility criteria:
Inclusion Criteria:

        absence of sperm cells on 2 spermograms in 3 months interval testicular size has to be
        determined in order to categorized in a group to accept surgery-

        Exclusion Criteria:

        allergy to fluoro deoxyglucose clinical varicocele
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Entailment
Clinical trial: Topical Agent for Treatment of Red Skin (NCT00279890)

Eligibility criteria:
Bilaterally symmetric red skin on cheeks Caucasian Age 18-60 years
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of Comprehensive Diagnosis and Treatment for Children Precocious Puberty (NCT02920515)

Eligibility criteria:
Inclusion Criteria:

          1. Premature appearance of secondary sexual characteristics: girls present with
             development of secondary sexual characteristics before 8, with breast induration as
             the earliest manifestation.

          2. Accelerated linear growth: the annual growth rate is higher than normal.

          3. Advanced bone age: the bone age is 1 or years more than the actual age

          4. Enlargement of sexual glands: B-mode ultrasonography of pelvic cavity indicates the
             volumes of the uterus and ovaries have increased, and multiple ovarian follicles with
             a diameter>4mm can be found in ovaries;

          5. HPGA functions have been primed; serum gonadotropin and sexual hormone levels reach
             pubertal values.

          6. Subjects should be willing and able to follow the study protocol during the study
             period.

          7. Subjects should submit their parents' or guardians' written informed consent before
             initiation of the study procedure with non-normal medical care. They should understand
             that subjects or their parents/guardians may withdraw the consent at any time without
             impairing future medical care. If the child is old enough to read and write, she
             should submit a separate consent form.

        Exclusion Criteria:

          1. Patients with central nervous system diseases and thyroid diseases;

          2. Patients with CHA-induced precocious puberty;

          3. Patients with poor compliance.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 14 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction