araag2/NLI4PR huggingface dataset:
Clinical trial: The Accuracy of Automated Audiometry Application on Smart Phone to Screen Hearing Loss (NCT02840266)

Eligibility criteria:
Inclusion Criteria:

          -  Patient who underwent hearing test in our otologic clinic

        Exclusion Criteria:

          -  Age below 15 year

          -  Patients who cannot following command
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 15 Years old.


Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Entailment
Clinical trial: Comparative Study of Safety and Efficacy of Heavyweight and Partially Absorbable Mesh in Inguinal Hernia Repair (NCT01877122)

Eligibility criteria:
Inclusion Criteria:

          1. Male patients >=20 years =<85 years old

          2. Patients with Unilateral hernia

          3. Patients without previous operations in lower part of abdomen

          4. Patients capable to understand the explanation about purpose and method of the trial,
             and write an Informed Concent Form

          5. Patients capable to participate during the period of the trial

        Exclusion Criteria:

          1. Previous hernia repair at the same site

          2. Incarcerated hernia

          3. Strangulated hernia

          4. Patients to whom and open surgery cannot be indicated

          5. Previous urological surgery

          6. Immune incompetence of patient: AIDS, vesical fibrosis, etc.

          7. Patients with AIHD or patients who take immunosuppressive drugs

          8. Patients with liver disease (ASL, AST ≥ normal value by more than 3 times)

          9. Patients with kidney disease (creatinine>2.0mg/dL)

         10. Patients on anti-coagulants

         11. Patients with severe systematic disease

         12. Patients with malignant tumor

         13. Patients with infection or with the predicted problem of surgery site healing

         14. Participation in another clinical study within the last 30 days

         15. Patients whose participation is considered inappropriate according to other except
             above mentioned clinical condition
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Prevention of Severe Covid-19 in Infected Elderly by Early Administration of Convalescent Plasma With High-titers of Antibody Against SARS-CoV2 (NCT04479163)

Eligibility criteria:
Inclusion Criteria:

        - Age ≥ 75 or age 65-74 with at least 1 of the following comorbidities: arterial
        hypertension, diabetes, obesity, chronic obstructive pulmonary disease, heart disease,
        chronic kidney disease

          -  Last 48 hours: (A)Axillary temperature ≥ 37.5oC or febrile equivalent, combined with
             (a) dry cough and/or (b) breathing difficulty and/or (c) odinophagia and/or (d)
             anosmia/dysgeusia and/or (e) any of the following symptoms: fatigue, anorexia,
             myalgias or rhinorrhea.

          -  Confirmed diagnosis SARS-Cov2 by RT-PCR

          -  Give Informed consent

        Exclusion Criteria:

          -  Severe respiratory disease

          -  Cardiac insufficiency,

          -  Chronic renal failure,

          -  Primary hypogammaglobulinemias,

          -  Myelodysplastic syndromes,

          -  Chronic linfoproliferative syndromes,

          -  Monoclonal gammapathies,

          -  Known hypersensitibility,

          -  Active cancer,

          -  HIV, HBV or HCV infection,

          -  Chronic administration of immunosuppressants,

          -  Body transplant history,

          -  Chronic liver disease, Chronic lung disease with oxygen requirement.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis (NCT03277066)

Eligibility criteria:
Inclusion Criteria:

          -  Male or female aged 40 to 85 years with a clinical diagnosis of OA of the target knee
             according to the American College of Rheumatology (ACR) criteria, including:

          -  Symptoms for at least 6 months prior to screening, AND

          -  Knee pain in the target knee for 30 days of the preceding month (periarticular knee
             pain due to OA and not due to other conditions such as bursitis, tendonitis, etc.) AND

          -  The pain in the target knee required the use of nonsteroidal anti-inflammatory drugs
             (NSAIDs) either over the counter (OTC) per recommendation of a physician or
             prescribed.

        Exclusion Criteria:

          -  Body mass index (BMI) > 40

          -  Any subject who disobeyed the restriction of prohibited therapies (i.e., use rescue
             medication) during Screening Washout Period.

          -  Secondary OA of the knee (rheumatoid arthritis, gout, psoriasis, syphilitic
             neuropathy, ochronosis, metabolic or other primary bone disease or acute trauma).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: Autophagy and Pathological Aging (NCT03175874)

Eligibility criteria:
Inclusion Criteria:

        Inclusion criteria for both groups:

          -  Women > 65 y: 2 groups

        Inclusion criteria for Osteoporosis group (Alzheimer and non-Alzheimer):

          -  Osteoporotic femoral neck fracture requiring hip remplacement and fullfilling WHO
             definition of osteoporosis. Without any cognitive impairment for the first subgroup
             (MMSE > 26 and normal IADL) and with a final diagnosis of alzheimer disease in the
             other subgroup (DSM-IV-TR)

        Inclusion criteria for Control group:

          -  Non osteoporotic (no fragility fracture (clinical or on VFA) and bone mineral density
             T-score > 2.5 SD at all sites)

          -  No cognitive impairment (MMSE > 26 and normal IADL)

        Exclusion Criteria:

        Non-Inclusion Criteria for both groups:

          -  Other pathologies associated with autophagy: Parkinson's disease, Crohn's disease,
             cancers, myopathies, type 2 diabetes

          -  Méd Medications interfering with autophagy: current corticosteroids, parathyroid
             hormone, estrogen, chloroquine, hydroxychloroquine, lithium, metformin,
             bisphosphonates,

          -  Dementia of non-Alzheimer type
Female
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Effectiveness of Smart Health Management Program for Patients With Chronic Illness (NCT03294044)

Eligibility criteria:
Inclusion Criteria:

          -  Subject 19 years old and more

          -  Subject who understands the purpose of the study and signs with informed consent form

          -  Subject with chronic disease (hypertension, diabetes, dyslipidemia)

          -  Subject with more than one Poor Disease Control Indicator

               1. HbA1C 7.0% or more

               2. Systolic BP 140mmHg or more

               3. LDL-cholesterol 130mg/dL or more

          -  Subjects who use smart phones and PCs (those who can use ICT-based health care
             programs)

        Exclusion Criteria:

          -  Inability to speak, understand, or write Korean

          -  Inability to understand the contents of the provided materials due to poor eyesight
             and hearing

          -  Medical conditions that would limit adherence to participation of the clinical trial
             (as confirmed by their referring physician; e.g. dyspnea, severe depression and other
             mental disorders)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Update in VWD Laboratory Diagnosis (NCT03896997)

Eligibility criteria:
Inclusion Criteria:

          -  Patients referred for VWD diagnosis or previously diagnosed with VWD

        Exclusion Criteria:

          -  Patients with other bleeding disorders
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation (NCT00763399)

Eligibility criteria:
Inclusion Criteria:

          -  Diarrhea

          -  constipation

        Exclusion Criteria:

          -  Shock

          -  Sepsis

          -  Past history with GI tract surgery

          -  Immunodeficiency
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 3 Months old.
Subject must be at most 10 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Ecological Momentary Assessment of Eating Behavior in Overweight Youth (NCT02585518)

Eligibility criteria:
Inclusion Criteria:

        Participants be included if they are overweight or obese (BMI≥85th %ile) and aged 8-14
        years.

        Exclusion Criteria:

        Participants will be excluded if they 1) are currently taking any medications known to
        affect weight or appetite (e.g., antidepressants, steroids, chemotherapy drugs); 2) have a
        current or past diagnosis of an eating disorder involving purging or suppressed body weight
        (e.g., bulimia nervosa or anorexia nervosa); 3) are unable to read and understand English
        fluently; or 4) are receiving concurrent treatment for obesity.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 8 Years old.
Subject must be at most 14 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Pulsed Electromagnetic Field Treatment for Painful Periods (NCT03394547)

Eligibility criteria:
Inclusion Criteria:

          -  Female with persistent (>3months) cyclical period pain associated with menstruation
             (defined as 5 or more on VAS).

          -  Able to give written, Informed consent

          -  Able to wear device and keep up-to-date records of use

          -  Agrees to attend follow up

          -  If currently using hormonal contraception agrees to continue on the same dose for the
             duration of the trial.

        Exclusion Criteria:

          -  Age under 16 years.

          -  Trying to conceive or <6 weeks post partum

          -  Currently participating or planning to participate in another clinical trial
Female
Accepts Healthy Volunteers
Subject must be at least 16 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment