araag2/NLI4PR huggingface dataset:
Clinical trial: Bedside Screening Method for Patients With Potential Swallowing Impairment (NCT01158313)

Eligibility criteria:
Inclusion Criteria:

          -  History of swallowing difficulties associated with aging and/or neurological diseases
             including patients with: -neurodegenerative diseases. -non-progressive neurological
             diseases including stroke. -older patients including nursing home patients.

          -  Age > 18 y

          -  Ability to give informed consent

        Exclusion Criteria:

          -  Patients suffering idiosyncratic phenomena or who are allergic to any medication,
             especially iodinated contrast media

          -  Patients suffering major respiratory disease or undergoing any type of surgery in the
             three months prior to the study

          -  Patients with a background of alcohol dependence or other drug dependence

          -  Patient who cannot be expected to comply with treatment

          -  Patient currently participating or having participated in another clinical trial
             during the last 4 weeks prior to the beginning of this study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? Entailment
Clinical trial: Proliferation of Endometrial Stromal Cells in Adenomyosis (NCT00173212)

Eligibility criteria:
Inclusion Criteria:

          -  women with adenomyosis

          -  at early- to mid-secretory phases

        Exclusion Criteria:

          -  postmenopausal

          -  malignancy
Female
Accepts Healthy Volunteers
Subject must be at least 35 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Entailment
Clinical trial: MiCo - Mirena or Conventional Medical Treatment for Menorrhagia (NCT01085487)

Eligibility criteria:
Inclusion Criteria:

          -  Women between the ages of 18-45 (inclusive) not intending to become pregnant during
             the next year

          -  Women complaining of heavy menstrual bleeding over several consecutive cycles

          -  Women without structural or histological abnormality of the uterus, or with fibroids
             less than 3 cm in diameter which are causing no distortion of the uterine cavity
             (eligible for pharmaceutical treatment according to the NICE guideline 2007)

          -  Informed consent (where required by laws or regulations)

        Exclusion Criteria:

          -  The contraindications and warnings of the respective Summary of Product
             Characteristics (Mirena®, combined oral contraceptives, oral/injectable progestogens,
             non-steroidal anti-inflammatory drug, or anti-fibrinolytic agent) must be followed.

          -  Women taking hormone replacement therapy

          -  Women with symptoms such as intermenstrual or post-coital bleeding, unless an
             endometrial biopsy has been performed and pathology excluded

          -  Women with fibroids that are palpable abdominally or who have intra-cavity fibroids
             and/or whose uterine length as measured at ultrasound or hysteroscopy is greater than
             12 cm (NICE guideline 2007)

          -  Women on anticoagulative therapy or other treatment (including e.g. Copper IUD use)
             known to cause menorrhagia
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? Entailment
Clinical trial: Pain Expectations in Subjects With Osteoarthritis (NCT02155257)

Eligibility criteria:
Inclusion Criteria:

          -  Osteoarthritis of the knee or hip

          -  Adult (ages 18-80)

          -  Moderate pain (verbal score of ≥ 4 ≤ 7 on 0-10 scale for average pain intensity with
             normal activity)

          -  American Society of Anesthesiologists physical status 1-3

          -  Healthy subjects without pain

        Exclusion Criteria:

          -  Pregnancy;

          -  Currently taking gabapentin

          -  Currently taking a narcotic prescription medication that is > 50 mg morphine
             equivalents/day

          -  Advanced or unstable cardiac, pulmonary, renal or hepatic dysfunction

          -  History of previous eye surgery

          -  Psychotic disorder or a recent psychiatric hospitalization
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: Point-of-Care Ultrasound in the Emergency Department Evaluation of Syncope (NCT01671371)

Eligibility criteria:
Inclusion Criteria:

          -  18 years and older presenting to the ED with acute syncope (defined as transient loss
             of consciousness) or near syncope (sensation of impending but not actual loss of
             consciousness) as a reason for ED visit.

        Exclusion Criteria:

          -  persistent altered mental status

          -  alcohol or illicit drug-related loss of consciousness

          -  definite seizure, and transient loss of consciousness caused by head trauma.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: Optical Coherence Tomography Comparative Study (NCT00069199)

Eligibility criteria:
INCLUSION CRITERIA:

          1. Patient must understand and sign the informed consent.

          2. Patient must be at least 18 years of age.

          3. Pupillary dilation to at least 6 mm must be possible.

          4. Ocular media must be sufficiently clear to allow for quality images.

        EXCLUSION CRITERIA:

        1. Any condition such as corneal opacifiation that precludes adequate slit lamp examination
        and photography of the fundus.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient description (patient's own words): I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Does the patient match the trial criteria? Entailment
Clinical trial: A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain (NCT00361504)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of knee or hip osteoarthritis with history of pain at the reference
             joint for at least 3 months or clinical diagnosis of low back pain of benign origin
             for at least 3 months

          -  Must be dissatisfied with their current analgesic therapy (e.g. Non-steroidal
             anti-inflammatory drugs NSAIDS, COX-2 inhibitors, opioids, paracetamol/acetaminophen

          -  Have a pain intensity >4 on Numerical Rating Scale

        Exclusion Criteria:

          -  Life-long history of seizure disorder or epilepsy

          -  Any of the following within one year: mild/moderate traumatic brain injury, stroke,
             transient ischemic attack, and brain neoplasm

          -  Severe traumatic brain injury within 15 years (consisting of more than one of the
             following: brain contusion (injuries resulting in hemorrhage), intracranial hematoma,
             unconsciousness or post traumatic amnesia lasting for more than 24 hours) or residual
             sequelae suggesting transient changes in consciousness

          -  History of malignancy within past 2 years, with exception of a successfully treated
             basal cell carcinoma

          -  Presence of significant pain associated with conditions other than osteoarthritis or
             low back pain that could confound the assessment or self-evaluation of pain
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment
Clinical trial: RCT Novasure Versus Novasure + Mirena IUS in the Treatment of Menorrhagia (NCT01965587)

Eligibility criteria:
Inclusion Criteria:

          -  Anybody suitable for novasure ablation

        Exclusion Criteria:

          -  Mirena IUS is indicated as treatment
Female
Accepts Healthy Volunteers



Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: The KEN SHE Study on HPV-vaccine Efficacy (NCT03675256)

Eligibility criteria:
Inclusion Criteria:

          -  Born female

          -  Age 15 to 20 years

          -  HIV-negative

          -  No history of HPV vaccination

          -  Sexually active: history of 1-5 lifetime partners

          -  Resident within study area without plans to move away in the next 37 months

        Exclusion Criteria:

          -  Allergies to vaccine components or latex,

          -  Pregnancy

          -  Hysterectomy

          -  Autoimmune, degenerative, and genetic diseases

          -  Investigator discretion
Female
Accepts Healthy Volunteers
Subject must be at least 15 Years old.
Subject must be at most 20 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Study of Pain Catastrophizing (NCT03836586)

Eligibility criteria:
Inclusion Criteria:

          -  symptomatic knee OA

        Exclusion Criteria:

          -  Younger than 45 years of age or older than 85 years of age

          -  Prosthetic knee replacement or other clinically significant surgery to the arthritic
             knee

          -  uncontrolled hypertension (>150/95)

          -  Heart disease including heart failure

          -  Peripheral neuropathy in which pain testing was contraindicated

          -  Systemic rheumatic disorders including rheumatoid arthritis, systemic lupus
             erythematosus, gout, and fibromyalgia

          -  Neurological diseases such as Parkinson's, multiple sclerosis, stroke with loss of
             sensory or motor function, or uncontrolled seizures

          -  Significantly greater pain in body sites other than in the knee

          -  Daily opioid use

          -  Hospitalization within the preceding year for psychiatric illness

          -  Currently pregnant or nursing/breastfeeding
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Entailment