araag2/NLI4PR huggingface dataset:
Clinical trial: The Effects of Joint Effusion on Proprioception (NCT01060215)

Eligibility criteria:
Inclusion Criteria:

        Or at least two of criteria 2-6 established by the American College of Rheumatology (ACR):

          1. Kellgren and Lawrence (K/L) grade ≥II

          2. morning stiffness <30 min in duration

          3. crepitus on movement of the knee joint

          4. bony tenderness at the knee joint margins

          5. palpable or visible bony enlargement

          6. no palpable warmth.

        Exclusion Criteria:

          1. the presence of knee joint effusion determined by ultrasonography

          2. a history of knee injury or surgery

          3. a history of knee injection within 3 months

          4. a history of inflammatory arthritis

          5. taking anticoagulants

          6. balance or gait disturbance

          7. diabetes mellitus.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Entailment
Clinical trial: Fascial Therapy in Elbow Hemophilic Arthropathy (NCT03009591)

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed with hemophilia A and B

          -  Patients adults (over 18 years)

          -  Patients diagnosed with hemophilic arthropathy of the elbow (by clinical assessment
             with the Hemophilia Joint Health Score)

          -  Patients pn prophylactic treatment with FVIII / FIX concentrates.

        Exclusion Criteria:

          -  Patients without ambulation ability

          -  Patients with inhibitors

          -  Patients with neurological or cognitive alterations that impede the comprehension of
             the questionnaires and physical tests

          -  Patients who have not signed the informed consent document.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Contradiction
Clinical trial: The Berkeley Orthokeratology Study (NCT00000123)

Eligibility criteria:
Myopic volunteers, ages 20 to 35, who had not worn contact lenses were eligible to
        participate in the study if they were free of ocular disease, were in good physical health,
        and were not taking systemic medications that could have ocular side effects. In addition,
        eligibility was limited to persons with corneal curvature between 40.50 and 47.00 D
        (flatter keratometry reading), corrected visual acuity of 6/6 (20/20) or better in each
        eye, astigmatism less than 0.75 D, anisometropia less than 1 D, and myopia between 1 and 4
        D.
No condition on gender to be admitted to the trial.

Subject must be at least 20 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient description (patient's own words): I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Does the patient match the trial criteria? Entailment
Clinical trial: Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART (NCT03423537)

Eligibility criteria:
Inclusion Criteria:

          1. Age: between 35 and 40 years of age,

          2. Physiological menstrual cycles (24-35 day cycle),

          3. Normal endocrine function (normal PRL and TSH, FSH ≤ 15 IU / ml),

          4. Transvaginal ultrasound (TVS) without pathological findings,

          5. Free personal medical history,

          6. Indication for IVF / ICSI (NICE, 2016)

          7. 1st or 2nd IVF / ICSI cycle

        Exclusion Criteria:

          1. Endocrine or metabolic disorders, e.g. PCO (S)

          2. Pathology of the uterus and / or endometrium,

          3. Pelvic inflammatory disease (PID),

          4. Basal FSH levels> 15 IU / ml,

          5. Surgery in the ovaries,

          6. Body Mass Index (BMI) ≥ 35 kg / m2,

          7. Age: <35 years &> 41 years old
Female
Accepts Healthy Volunteers
Subject must be at least 35 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Modern Analyses of the Semen in Evaluating Male Fertility and Treatment Options of Male Infertility (NCT02932865)

Eligibility criteria:
Inclusion Criteria:

          -  Ability to produce semen sample

        Exclusion Criteria:

          -  Cognitive impairment

          -  Inadequate language skills for informed consent
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient description (patient's own words): I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Does the patient match the trial criteria? Entailment
Clinical trial: PREPARE-IBD: Physician Responses to Disease Flares and Patient Adaptation in Relation to Events in Inflammatory Bowel Disease During COVID-19 Pandemic (NCT04410484)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with IBD +/- flare +/- COVID 19 positivity

        Exclusion Criteria:

          -  Patients below 16

          -  Patient with inactive IBD
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 16 Years old.
Subject must be at most 100 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: A Single Center Study to Demonstrate the Safety and Performance of Lifelight® First Software Application (NCT03998098)

Eligibility criteria:
Inclusion Criteria:

          1. Subject is informed and has been given ample time and opportunity to think about
             his/her participation and has given his/her written informed consent

          2. Subject is ≥18 years of age

          3. Subject's health status: individual is considered to be healthy (hypertension and
             hypotension is permissible. Other stable diseases at the time of testing are also
             permissible)

          4. Subject is capable of undergoing controlled hypoxaemia to the levels called for the in
             the protocol with minimal medical risk (unless only participating in the blood
             pressure study).

        Exclusion Criteria:

          1. Subject cannot expose their face fully for a reading to be taken

          2. Subject is unable to give informed consent

          3. Subject is outside of the specified age range

          4. Subject has already taken part in the study (all 4 sub studies)

          5. Subject with significant irregular heart rhythm or any disease that might affect the
             results of the study

          6. Subject is not capable of undergoing controlled hypoxia and would be placed at undue
             medical risk if this occurred

          7. Subject has any contraindications identified that would deem them unsuitable to take
             part
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Validation of Wrist Type Oscillometric Blood Pressure Monitorings (NCT04633785)

Eligibility criteria:
Inclusion Criteria:

          -  above 12 years old

        Exclusion Criteria:

          -  unclear Korotkoff sounds

          -  wrist circumference outside of the designated range (13.5-23 cm)

          -  arrhythmias
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 12 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Position of EGD in Droplet Spreading (NCT04329013)

Eligibility criteria:
Inclusion Criteria:

          -  Patients who have the indication for upper gastrointestinal endoscopy

        Exclusion Criteria:

          -  Cannot be in prone position

          -  The endoscopist deny the assigned position in any reason.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Randomized Multicentre Study Comparing TEP With Lichtenstein Repair for Primary Inguinal Hernia (NCT00568269)

Eligibility criteria:
Inclusion Criteria:

          -  Male

          -  Age 30-70 years referred to hospital with a primary inguinal hernia.

        Exclusion Criteria:

          -  Recurrent hernia

          -  Scrotal or bilateral hernia

          -  Previous lower abdominal surgery

          -  Unable to participate in follow up

          -  ASA more than 3

          -  Bleeding diathesis.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: Development and Testing of a Jamaican Mother-daughter HIV Risk-reduction Program (NCT03411577)

Eligibility criteria:
Inclusion Criteria:

        Inclusion criteria for the adolescent include:

          -  age between 13- to 17-years, inclusive

          -  resident of one of the three parishes in and around Kingston, Jamaica (the study area)

          -  plan to reside in the "study area" for the next 12 months

          -  able to read, write and understand English

          -  unmarried and

          -  agrees to participate and

          -  mother or primary female guardian also agrees to participate.

        Inclusion criteria for the mother/female guardian include:

          -  age greater than 18

          -  resident of one of the three parishes in and around Kingston, Jamaica (the study area)

          -  plan to reside in the "study area" for the next 12 months

          -  able to read, write and understand English and

          -  agrees to participate

        Exclusion Criteria:

          -  adolescent and/or mother who is/are disruptive and/or otherwise unable to participate
             in small group intervention activities

          -  adolescent who is married
Female
Accepts Healthy Volunteers
Subject must be at least 13 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction