araag2/NLI4PR huggingface dataset:
Clinical trial: Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients (NCT01794026)

Eligibility criteria:
Inclusion Criteria:

          -  gastric adenocarcinoma proven by endoscopic biopsy;

          -  application of both computed tomography and diffusion weighted magnetic resonance
             imaging;

          -  standard gastrectomy and a D2 lymph node dissection;

          -  desire to attend the study protocol

        Exclusion Criteria:

          -  preoperative neoadjuvant therapy;

          -  metastatic disease;

          -  undesired reaction to attend the study protocol
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Integrating the Clinical Pharmacists Into Emergency Department Teams (NCT04722588)

Eligibility criteria:
Inclusion Criteria:

          -  All patients presenting to the EDs during the study period will be included as far as
             they do not actively ask to not be included in the study. Patients presenting during
             the control period, will be allocated to the control group, while patients presenting
             during the intervention period will be allocated to the intervention group,
             indeependently of whether they receive clinical pharmacist services or not.

        Exclusion Criteria:

          -  Patients for whom data is not available retrospectively.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Inguinal Hernia Repair on Uroflowmetric Parameteres (NCT03450811)

Eligibility criteria:
Inclusion Criteria:

          -  any type of inguinal hernia

        Exclusion Criteria:

          -  active urinary tract infection,

          -  previous BPH, neurological disease or significant systemic disease,

          -  medications that could interfere voiding function

          -  history of prostate, bladder or urethral surgery or traumatic urethral
             catheterisation.
Male
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? Entailment
Clinical trial: A Non-invasive Device to Remove Fluid From the Middle Ear (NCT03978195)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosed with ear fluids (OME) according to a doctor's examination for at least 4-6
             weeks. There is a progressive hearing impairment and a matching tympanum.

          -  In principle, these children (with OME and hearing impairment) meet the criteria and
             candidates for the analysis of inserting tubes of incontinence (buttons).

        Exclusion Criteria:

          -  First encounter: acute ear infection or Proper Otoscopy

          -  Second session: First review: Otoscopy / Timpneometry / Hearing test.

          -  Parallel treatment: acupuncture - tubes insertion - discontinuation of follow-up -
             cessation of the experiment initiated by parents
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.
Subject must be at most 10 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Contradiction
Clinical trial: COVID-19 Pathophysiology of Long Term Implications (NCT04813575)

Eligibility criteria:
Inclusion Criteria:

          -  Patients presenting with COVID symptoms to hospitals.

          -  Patients >18 years old

        Exclusion Criteria:

          -  Patients without capacity to consent

          -  Pulmonary oedema secondary to decompensated cardiac, renal or liver disease at the
             time of admission

          -  Interstitial lung disease at the time of presentation

          -  Known lymphangitis carcinomatosis

          -  Morbidly obese patients with BMI more than 40

          -  Patients with known pulmonary hypertension or if the clinician feels there are other
             reasons for pulmonary hypertension than cardiomyopathy secondary to COVID 19.

          -  Pregnant women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Entailment
Clinical trial: Double Blind Study to Evaluate the Efficacy of Collagenase Histolyticum in the Treatment of Lipoma (NCT02249052)

Eligibility criteria:
Inclusion Criteria:

          -  18-75 years of age, of either sex or any race

          -  Clinical history of at least 2 lipomas for at least one year

          -  Lipomas diagnosed as benign

          -  Two lipomas on distinctly separate parts of the body, or on the torso if 30 cm apart,
             with easily definable edges

          -  Each lipoma is a single mass with easily definable edges

          -  Lipomas are 5 to 24 cm squared

          -  Women of childbearing potential must use an acceptable method of birth control

        Exclusion Criteria:

          -  Lipomas on the head, neck, hand or foot, or female breast

          -  Women who are nursing or pregnant

          -  Multi-lobular lipomas

          -  Subjects who have received an investigational drug within 30 days before receiving the
             first dose of study drug in this study

          -  Subjects with a known allergy to collagenase or any of the inactive ingredients in
             XIAFLEX

          -  Subjects with uncontrolled diabetes, hypertension, or thyroid disease, or any medical
             condition that would make the subject unsuitable for enrollment

          -  Subjects having prior treatment or trauma of the lipoma that could interfere with
             study assessments

          -  Subjects with a history of connective tissue diseases, rheumatological diseases

          -  Subjects taking anticoagulants or planning to receive anticoagulants (except for lo
             dose aspirin and over-the-counter nonsteroidal anti-inflammatory drugs) within 7 days
             of injection of study drug
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? Entailment
Clinical trial: A Phase IIb Multicentre, Double-Blind, Dose-Ranging, Randomised, Placebo-Controlled Study Evaluating Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism (NCT02730169)

Eligibility criteria:
Inclusion Criteria:

          -  Adult male subject aged 18 to 65 years inclusive

          -  BMI > 30 kg/m2 and < 50 kg/m2

          -  Serum total testosterone concentration below the normal range

          -  LH levels below the upper limit of normal

          -  Oestradiol levels within or above the normal range of approved assay

          -  At least two symptoms of androgen deficiency present for at least 2 months prior to
             the first Screening Visit, with at least one of these being a sexual dysfunction

        Exclusion Criteria:

          -  Evidence of clinically significant endocrinopathy at screening that may interfere with
             the study assessments

          -  Other types of hypogonadotropic hypogonadism or primary hypogonadism

          -  Any other pituitary or hypothalamic disease
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus (NCT02443311)

Eligibility criteria:
Inclusion Criteria:

          -  clinically and histologically confirmed painful Erosive or Atrophic OLP

          -  free from any systemic diseases using medical questionnaire guided by Cornell Medical
             Index

        Exclusion Criteria:

          -  history of drug induced lichenoid lesions

          -  potential treatment of OLP for less than 2 weeks by topical and 4 weeks systemic
             therapy before study start

          -  pregnant or breast-feeding women,

          -  smoking and

          -  known hypersensitivity or severe adverse effects to the treatment drugs or to any
             ingredient of their preparation

          -  loss of paliability or flexibility in the tissues involved by the oral lesions or
             histological signs of epithelial dysplasia or lichenoid lesions within the biopsied
             sites.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effectiveness Intraarticular Corticosteroid (NCT01851278)

Eligibility criteria:
Inclusion Criteria:

          -  patients with established RA

          -  age between 18 and 65 years

          -  disease modifying anti-rheumatic drugs (DMARDs) stable for at least 3 months

          -  synovitis in wrist with pain visual analogic scale (VAS) between 4 and 8cm

        Exclusion Criteria:

          -  patients with overlap syndromes

          -  polyarticular synovitis

          -  diabetes mellitus or uncontrolled hypertension and those with suspected local or
             systemic infection
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Contradiction
Clinical trial: Long-term Lifestyle Change and Testosterone Replacement (NCT03256292)

Eligibility criteria:
Inclusion Criteria:

          -  Overweight/obese (BMI = or > 27 kg/m2)

          -  Older (65-85 yr)

          -  Male veteran patients being seen at the PI's endocrine clinic and receiving standard
             of care consisting of diet and regular exercise counseling

          -  Diagnosed with hypogonadism on current or previous testosterone replacement at the
             PI's endocrine clinic

          -  Willing to provide informed consent

        Exclusion Criteria:

          -  Failure to provide informed consent

          -  Unstable cardiopulmonary disease (e.g. recent MI, unstable angina, stroke) or unstable
             disease (Class III or IV congestive heart failure).
Male
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction