araag2/NLI4PR huggingface dataset:
Clinical trial: Caffeine and Sodium Citrate Ingestion (NCT01591226)

Eligibility criteria:
Inclusion Criteria:

          -  wheelchair athletes

          -  national team

          -  category T53 and T54

        Exclusion Criteria:

          -  medicated

          -  pregnant (for women)

          -  cardiovascular and respiratory diseases
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? 0
Clinical trial: 3D Radiographic Evaluation of a Novel Implant Site Development Technique (NCT02660697)

Eligibility criteria:
Inclusion Criteria:

        Presence of at least 1 single rooted tooth scheduled for extraction with EDS Class 3-4 type
        buccal bony dehiscence

        Exclusion Criteria:

        Exclusion criteria int he test group included uncontrolled inflammation at the surgical
        site, full mouth plaque or bleeding scores more than 20%, diabetes, pregnancy, known
        metabolic bone diseases, smoking more than 10 cigarettes a day, history of any relevant
        systemic diseases, radiotherapy chronic use of bisphosphonates or systemic steroids.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0
Clinical trial: Veritas Laparoscopic Paraesophageal Hiatal Hernia (PEH) Repair Pilot Trial (NCT01195545)

Eligibility criteria:
Inclusion Criteria:

        A. Subjects must have a documented symptomatic paraesophageal hernia that:

          -  1. Is greater than 5 cm hiatal hernia on Upper Gastrointestinal (UGI) series

          -  2. Has evidence that the stomach or other viscera is present in the hernia and does
             not spontaneously reduce from the mediastinum

          -  3. Has significant symptoms or signs of a paraesophageal hernia: heartburn, dysphagia,
             chest pain, shortness of breath, post-prandial abdominal pain, early satiety,
             odynophagia or chronic anemia

        B. Consenting adult ≥18 years ~ documentation of informed consent will be recorded in the
        research records

        C. Must be able to participate in follow-up evaluations (subjects must be fully cognitive)

        D. Has a telephone

        E. Free of cognitive or speech impairment

        Exclusion Criteria:

        A. Previous operation of the esophagus or stomach

        B. Associated gastrointestinal diseases that require extensive medical or surgical
        intervention that might interfere with quality of life assessment (e.g. Crohn's disease)

        C. Emergent operation for acute volvulus (twisting/rotation of the bowel leading to
        obstruction)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 1
Clinical trial: Research of Biomarkers in Duchenne Muscular Dystrophy Patients (NCT01380964)

Eligibility criteria:
Inclusion Criteria:

          -  FOR PATIENTS:

          -  Diagnosis of DMD confirmed by genetic testing

          -  Age over 3 years

          -  Weight over 15 kg

          -  Informed consent signed

          -  FOR CONTROLS:

          -  Age over 3 years

          -  Male gender

          -  Weight over 15 kg

          -  Subjects with national health insurance coverage

          -  Informed consent signed

          -  Nonacute or chronic muscular, allergic, infectious, endocrine or inflammatory disorder
             in the 3 weeks preceding inclusion

        Exclusion Criteria:

          -  FOR PATIENTS:

          -  Concomitant chronic or acute muscular, endocrine, infectious, allergic or inflammatory
             disorder in the three weeks preceding the blood test

          -  Intake of medicines other than angiotensin-converting enzyme inhibitors, beta
             blockers, dietary supplements, vitamins, alendronate and methylphenidate. Steroids
             (and medicines prescribed with them such as calcium supplements and proton pump
             inhibitors) will be discussed

          -  Mental retardation or autism

          -  Vaccination or treatment with immunoglobulins within the three months preceding
             inclusion

          -  FOR CONTROLS:

          -  Concomitant chronic or acute muscular, neurological (including mental retardation and
             autism), infectious or inflammatory disorder in the three weeks preceding the blood
             test

          -  Vaccination or treatment with immunoglobulins within the three months preceding
             inclusion
Male
Accepts Healthy Volunteers
Subject must be at least 3 Years old.
Subject must be at most 20 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? 1
Clinical trial: Genetic Studies in Familial Dementia (NCT04680013)

Eligibility criteria:
Inclusion Criteria:

          -  18 years and older

          -  Patients diagnosed with dementia, their family members and unrelated healthy controls
             without dementia.

        Exclusion Criteria:

        -Individuals with competing diagnosis such as Amyotrophic lateral sclerosis, Frontotemporal
        lobar degeneration, Multiple system atrophy, Corticobasal degeneration, Progressive
        Supranuclear Palsy, Huntington's disease, traumatic brain injury, drug or alcohol abuse, or
        schizophrenia, etc., unless family members of a dementia affected individual.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? 1
Clinical trial: The Role of Endobronchial Ultrasound Elastography in the Diagnosis of Mediastinal Lesions (NCT02724059)

Eligibility criteria:
Inclusion Criteria:

          -  Hilar/mediastinal lymph nodes with a short axis more than 1 cm on thoracic CT scan
             and/or PET-CT suspicious for malignancy with or without known lung malignancy.

          -  Hilar and/or mediastinal lymph nodes positive on PET/CT scan without regarding the
             diameter suspicious for malignancy.

          -  Recurrence or restaging of NSCLC after chemotherapy or radiation.

          -  Diagnosis of both benign and malignant mediastinal lesions.

        Exclusion Criteria:

          -  Cardiovascular instability.

          -  Lack of patient cooperation, e.g. intractable cough, inability to remain motionless or
             altered consciousness.

          -  Bleeding diathesis (activated partial thromboplastin time (APTT) ratio or
             international normalized ratio (INR) <1.3 or platelet count of <50000 per mm3).

          -  Border line respiratory failure and patient on mechanical ventilation.

          -  Severe chronic obstructive pulmonary disease (COPD) (FEV1<1 liter or <35% predicted).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? 1
Clinical trial: Yeahhh Baby! Ointment on Hip and/or Knee Pain in Men and Women (NCT04764552)

Eligibility criteria:
Inclusion Criteria:

          -  Self-reported joint pain with a minimum pain rating of 3/10 for at least the past 30
             days

          -  Recreationally active (2 or more days per week)

          -  Not obese (BMI < 30kg/m2)

        Exclusion Criteria:

          -  Tobacco users/Smokers

          -  Allergic to coconut, walnuts, oak, olives

          -  Currently using anti-inflammatory medicines or dietary supplements (and not willing to
             cease for one-month prior to participation and throughout study)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 35 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders (NCT02318875)

Eligibility criteria:
Inclusion Criteria:

          -  Male and female subjects;

          -  >18 years old;

          -  Complaining functional discomfort associated to joints and/or muscles disorders,
             motility disorders and/or initial SMFA score higher or equal to 15 ;

          -  Able to give a written or verbal informed consent,

          -  Affiliated or beneficiary of social security

        Exclusion Criteria:

          -  IMC>30kg/m

          -  Acute or chronic, progressive joint disorders (arthrosis, rheumatoid arthritis, acute
             articular rheumatism) of first or second degree and correlated treatments;

          -  Subjects refusing of giving their written or verbal informed consent

          -  Subjects deprived of freedom following an administrative or judicial decision

          -  Participation to another clinical trial in the last four weeks;

          -  People who already participated to another research that comprises an exclusion period
             still ongoing at the time of inclusion
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? 0
Clinical trial: Active Rehabilitation in Osteoporotic Patients (NCT01357278)

Eligibility criteria:
Inclusion Criteria:

          -  Proven low bone mineral density (t-score < 1.5) plus radius fracture

          -  The radius fracture must not be older than 2 years, and must be healed by start of
             intervention (no plaster cast)

          -  Postmenopausal women above 50 years

          -  Domicile in the Oslo region

        Exclusion Criteria:

          -  Hip fracture or vertebral fracture

          -  History of more than 3 osteoporotic fractures in different parts of the body

          -  Problems/illnesses indicating that active rehabilitation is not indicated

          -  Physical activity (moderate and hard intensity) for more than 4 hours a week

          -  Does not understand Norwegian, written and spoken
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 0
Clinical trial: Does Dehydro Epiandrosterone (DHEA) Improve Pregnancy Rate in Women Undergoing IVF/ICSI With Expected Poor Ovarian Response? (NCT02151006)

Eligibility criteria:
Inclusion Criteria:

          -  Women undergoing IVF/ICSI treatment with expected poor ovarian response according to
             the Bologna criteria

        Exclusion Criteria:

          -  Women with BMI >35 Kg/M2

          -  Women with a single ovary

          -  Known allergy to DHEA

          -  Diabetic women on insulin as insulin lowers DHEA levels and might reduce the
             effectiveness of DHEA supplements
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0