araag2/NLI4PR huggingface dataset:
Clinical trial: Observational Study of Long-Term Joint Health Outcome in Hemophilia Patient (NCT04618237)

Eligibility criteria:
Inclusion Criteria:

          1. Willing to sign inform consent form and complied with study procedure

          2. Patient received confirmative diagnosis of Hemophilia A Disease

          3. Severe hemophilia A patient currently who are on treatment with Eloctate prior to
             enrolment visit (Note: Prescription based on physician's clinical judgement and
             discussion with patients)

        Exclusion Criteria:

          1. Unwilling to sign inform consent form.

          2. History of major neurological disease (eg. Stroke, Parkinson's disease, neuropathy,
             etc.)

          3. History of major psychiatric disease (eg. Schizophrenia, bipolar disorder)

          4. Significantly impaired vision / hearing

          5. Cannot communicate in Mandarin Chinese

          6. Recent joint bleeding and trauma 3 months prior to study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0
Clinical trial: Hypogonadotropic Hypogonadism in Obese Young Males (NCT03245827)

Eligibility criteria:
Inclusion Criteria:

          -  Males

          -  Age 18-30 years inclusive will be recruited.

        A total of 90 males will be recruited:-

          -  30 obese males (defined as BMI ≥30 kg/m2) with HH,

          -  30 obese males with normal FT concentrations and

          -  30 lean males (defined as BMI <25 kg/m2) with normal FT concentrations.

        Exclusion Criteria:

          -  Use of androgens, clomiphene, hCG, aromatase inhibitors or over the counter health
             supplements which contain androgens currently or in the past 6 months

          -  Hematocrit > 50%

          -  Congestive heart failure

          -  currently suffering from depression

          -  type 1 diabetes

          -  Hepatic disease (transaminase > 3 times normal) or cirrhosis

          -  Renal impairment (eGFR<30 ml/min/1.73m2)

          -  HIV or Hepatitis C positive status

          -  Participation in any other concurrent clinical trial

          -  currently suffering from foot ulcer, significant periodontal disease or any other
             chronic infectious condition
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 0
Clinical trial: A Prospective Study of Misoprostol Administration in Asymptomatic Patients With Pregnancies of Unknown Location (NCT02581761)

Eligibility criteria:
Inclusion Criteria:

          -  hemodynamically stable women >18 years old with a PUL with abnormal plateauing serum
             βHCG trend

        Exclusion Criteria:

          -  Hemoglobin<10
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 1
Clinical trial: COVID-19 Thales Thermography Triage : Thermal Camera Feasibility Study (NCT04397380)

Eligibility criteria:
Inclusion Criteria:

          -  Patients ≥ 16 years old

          -  Patients able to read and understand English

          -  Patients able to give informed consent

          -  Patients being triaged through ED for any complaint (not necessarily COVID-19)

        Exclusion Criteria:

          -  Patients not meeting the inclusion criteria

          -  Patients who do not have capacity to consent

          -  Patients attending ED who are fast-tracked without triage
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? 1
Clinical trial: Urinary Retention After Laparoscopic Inguinal Hernia Repair: Comparing the Use of the Intraoperative Urinary Catheter (NCT03835351)

Eligibility criteria:
Inclusion Criteria:

          -  18 years of age or older

          -  Able to give informed consent

          -  Unilateral or bilateral inguinal hernia

          -  Scheduled for elective inguinal hernia repair

          -  Eligible to tolerate general anesthesia

          -  Eligible to undergo minimally invasive inguinal hernia repair

        Exclusion Criteria:

          -  Diagnosed with benign prostate hyperplasia (BPH)

          -  Younger than 18 years old

          -  Unable to give informed consent

          -  Emergent inguinal hernia repairs ( acute incarceration or strangulation)

          -  Unable to tolerate general anesthesia

          -  Not eligible for minimally invasive inguinal hernia repair
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X-Rays (NCT04313946)

Eligibility criteria:
Inclusion Criteria:

          -  flu-like symptoms: myalgia, cough, fever, sputum

          -  Chest X-Rays

          -  COVID-19 biological tests

        Exclusion Criteria:

          -  patient refusal

          -  uncertain radiographs

          -  uncertain tests results
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 0
Clinical trial: National Study of Moderate and Severe Von Willebrand Disease in the Netherlands (NCT00510042)

Eligibility criteria:
Inclusion Criteria:

          1. haemorrhagic symptoms or a family history of von Willebrand disease

          2. vWF antigen ≤ 30%, lowest measurement counts and/or vWF activity (vWF:RCo of vWF:CB) ≤
             30%, lowest measurement counts and/or FVIII:C ≤ 40 %, lowest measurement counts

          3. being known in a hemophilia treatment center or if only the diagnose is made in a
             hemophilia treatment center this must be done after 1987

        Exclusion Criteria:

          1. Hemophilia A

          2. Carriership of hemophilia A

          3. No informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? 1
Clinical trial: Laparoscopic vs Vaginal Hysterectomy for Benign Gynaecological Disease (NCT03692832)

Eligibility criteria:
Inclusion Criteria:

          -  Women undergoing hysterectomy for benign gynaecological disease (e.g., dysfunctional
             uterine bleeding, adenomyosis, fibroids).

        Exclusion Criteria: Women with:

          -  known tubo-ovarian pathology requiring primary laparotomy, e.g. large adnexal masses

          -  known neoplasia requiring pelvic lymphadenectomy

          -  pelvic organ prolapse requiring additional procedures, e.g., uterine procidentia
             (complete prolapse), enterocoele

          -  conditions interfering with laparoscopic surgery, e.g. cardio-pulmonary disease,
             obesity (BMI 30 kg/m2 or more)

          -  large uteri interfering with vaginal hysterectomy (size >16 gestational weeks)
Female
No healthy subjects accepted to join the trial.



Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 1
Clinical trial: Treatment Of Supracondylar Fractures Closed Reduction And Circular Ring External Fixation Versus Open Reduction and Internal Fixation (NCT02196311)

Eligibility criteria:
Inclusion Criteria:

          -  12 and 18 years old

          -  Supracondylar/periarticular humerus fracture needed operative fixation

          -  Fracture is unable to be treated with percutaneous skeletal fixation.

        Exclusion Criteria:

          -  Any previous elbow injury

          -  Osteogenesis imperfecta or another fragile bone disease

          -  Elbow stiffness from another cause

          -  Any pre-existing arm weakness.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 18 Years

Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? 1
Clinical trial: Gout Self-Monitoring Aiming to Reach Target (NCT03274063)

Eligibility criteria:
Inclusion Criteria:

          -  Confirmed diagnosis of gout (as per American College of Rheumatology criteria)

          -  Physician recommendation that escalation of urate lowering therapy with allopurinol or
             febuxostat is appropriate.

          -  Serum urate >0.36mm/L.

          -  Patient has a mobile phone and is able to install GoutSMART application.

        Exclusion Criteria:

          -  Subject is unable to provide consent

          -  Severe renal failure (eGFR <30) or established liver disease

          -  Previous adverse reaction to allopurinol or febuxostat
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? 0
Clinical trial: Gammaglobulins Level is Predictive Factor of Evolution in Sarcoidosis (NCT03259282)

Eligibility criteria:
Inclusion Criteria:

        - Patients newly diagnosed with sarcoidosis

        Exclusion Criteria:

          -  Comorbidity responsible for a change in the level of gamma globulin

          -  Other etiology of granulomatosis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient description (patient's own words): I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Does the patient match the trial criteria? 1