araag2/NLI4PR huggingface dataset:
Clinical trial: Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia (NCT03512366)

Eligibility criteria:
Inclusion Criteria:

          -  Primary uncomplicated inguinal hernia

          -  Male patients aged more than 18 years and less than 80 years

          -  BMI less than 30kg/sq m

          -  American Society of Anaesthesiologists (ASA) scale less than III

        Exclusion Criteria:

          -  Patients with recurrent, irreducible or strangulated inguinal hernias

          -  Patients unable to interpret VAS or give consent

          -  Patients participating in other clinical trials

          -  Patients with infection in the inguinal region or epididymo-orchitis

          -  Patients allergic to local anaesthetics
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Medication Abortion for Pregnancy of Unknown Location (NCT04026789)

Eligibility criteria:
Patients with an undesired pregnancy of less than or equal to 42 days gestation based on
        last menstrual period (LMP) who present to Planned Parenthood League of Massachusetts
        (PPLM)'s Greater Boston Health Center seeking medication abortion will be considered for
        study participation.

        Inclusion criteria:

          -  Positive urine or serum hCG test

          -  No evidence of gestational sac on transvaginal ultrasound

          -  Desire for medication abortion as method of pregnancy termination

        Exclusion criteria:

          -  Ineligible for medication abortion at PPLM based on current PPLM clinical guidelines

          -  Reasonable clinical suspicion for ectopic or molar pregnancy, such as abnormal or
             concerning ultrasound findings

          -  High risk for ectopic pregnancy, such as prior ectopic pregnancy, history of tubal
             surgery, concurrent intrauterine device in place during this pregnancy

          -  Exhibiting symptoms of possible ectopic, such as vaginal bleeding or abdominal pain

          -  LMP > 42 days or unknown LMP

          -  Age less than 18 years

          -  Prior participation in this study

          -  Anticipated inability to present for scheduled follow-up visits
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 1
Clinical trial: Probiotic Bacteria to Infants With Atopic Dermatitis (NCT01007331)

Eligibility criteria:
Inclusion Criteria:

          -  Atopic dermatitis

        Exclusion Criteria:

          -  Chronic diseases other than atopic dermatitis

          -  Chronic medication
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 24 Months

Patient description (medical language): A 2-year-old boy is brought to the office by his parents due to a rash that started 1 week ago.  A similar red, itchy rash on the cheeks, trunk, and arms has occurred intermittently since infancy.  The patient has had a few upper respiratory infections but no major illnesses.  Vaccinations are up to date, and he takes no medications. He is on a balanced diet, and he is healthy in appearance.  Vital signs and milestone examination are within normal limits.  Similar findings are observed on the cheeks and proximal upper extremities.  The diaper area is clear, and no mucosal lesions are present.

Patient description (patient's own words): I just brought my two-year-old son to the doctor's office because he had a rash for like one week. His rash was on the cheeks, the trunk, and his arms. He already had this before, and it keeps coming back from time to time to time. In the past, he had some respiratory infections but he has never been this sick. His vaccinations are up to date, and he doesn't take any medication. He's healthy with a nice diet. The doctor told me his vitals and milestone examinations were normal. The doctor also said there was a rash around the cheek and the upper part of his arms. The diaper area is okay, and there are no lesions.

Does the patient match the trial criteria? 0
Clinical trial: Essential Tremor in Children and Adolescent (NCT03487705)

Eligibility criteria:
Inclusion Criteria:

          -  Subject whose age is between 3 and 18 years

          -  Subject affiliated to a social security scheme

          -  Parents or subjects who have been informed of the course and consequences of the study
             by an investigator and who have signed the informed consent form for prospective
             inclusion or who have given their non-opposition for retrospective inclusion.

          -  Diagnosis of essential tremor established according to the diagnostic criteria of the
             Movement Disorders Society (1998), by a neuropediatrician or a neurologist, specialist
             in abnormal movements. The diagnosis is based on the presence of the following
             criteria: bilateral action tremor of the hands and forearms, absence of other
             neurological signs.

          -  Availability of an electromyogram for retrospective inclusions.

        Exclusion Criteria:

          -  Abnormal neurological examination outside tremor

          -  Family history or personal dysthyroidism

          -  Existence of a global psychomotor or motor developmental delay

          -  Taking medication that may induce tremor

          -  known poisoning by heavy metals, bismuth, mercury, methyl bromide

          -  Severe appearance of the tremor

          -  Tremor suggestive of a psychogenic origin

          -  Abnormal or non-existent brain MRI if family case
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.
Subject must be at most 18 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? 0
Clinical trial: Use of PRF in Treatment of Dry Socket. (NCT04476121)

Eligibility criteria:
Inclusion Criteria:

          -  no known medical history of abnormal platelet counts,

          -  patients with symmetric teeth qualified for extraction,

        Exclusion Criteria:

          -  patients treated previously for existing dry socket,

          -  patients allergic to acetylsalicylic acid ,

          -  systemic diseases,

          -  pregnancy,

          -  lactation,

          -  drugs known to affect the number or function of platelets,

          -  abnormal platelet counts,
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? 0
Clinical trial: Circulating Tumor Cells (CTCs) in Advanced Gastric Cancer (NCT01848015)

Eligibility criteria:
Inclusion Criteria:

          -  Having signed informed consent

          -  Age≥ 18 years old

          -  Histologically confirmed gastric adenocarcinoma

          -  Preoperative clinical examination and imaging indicating operable disease

          -  complete resection (R0 resection)

          -  D2 or D2+ resection

        Exclusion Criteria:

          -  Other tumor type than adenocarcinoma

          -  Patients who have been given preoperative chemotherapy/chemoradiation.

          -  Staging investigations or intraoperative exploration indicating inoperable disease

          -  R1 or R2 resection

          -  D0 or D1 resection

          -  Patients unreliable for follow up

          -  Past history of malignancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1
Clinical trial: Prolonged Symptoms and Reasons for Consultation in Town Medicine Associated With COVID-19 Infection in the Hauts de France Region (NCT04817293)

Eligibility criteria:
Inclusion Criteria:

        A- For COVID cases:

          1. Consultation in a city doctor's office

          2. Positive SARS-CoV-2 RT-PCR result OR positive SARS-CoV-2 serology

          3. Patient symptomatic or not

        Definition of symptomatic :

          1. Anosmia

          2. OR CT scan suggestive of COVID 19

          3. OR ≥ 2 symptoms contemporaneous with virologic sampling among: asthenia, cough,
             dyspnea, fever, myalgias, dysgeusia, diarrhea AND not present previously at diagnosis

        B-. For NON COVID cases:

          1. Consultation in a city doctor's office

          2. No known COVID+ serology

          3. No known RT- PCR SARS-CoV-2

          4. No clinical suspicion of COVID-19 infection

        Exclusion Criteria:

          1. Minor patient

          2. Refusal to participate

          3. Patient under protection

          4. Patient requiring hospitalization for COVID-19 (excluding non-emergency
             hospitalization)

          5. Patient consulted for the following reason only: treatment monitoring, treatment
             renewal or certificate, hospital discharge
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 1
Clinical trial: Genetic Causes of Male Infertility (NCT00341120)

Eligibility criteria:
-  INCLUSION CRITERIA INFERTILE MEN:

        Referred to the Scanian Andrology Centre.

        Age 20-45.

        Partner age less than 40.

        Having had regular sexual intercourse without contraception for a year or more without
        achieving a pregnancy.

        EXCLUSION CRITERIA INFERTILE MEN:

        Klinefelters syndrome.

        Hypogondotropic hypogonadism.

        Y-chromosome microdeletion or abnormality.

        Other genetic cause for infertility.

        Obstructive azoospermia.

        Partner with salpingitis.

        Partner with polycystic ovarian syndrome.

        Partner with disturbance of ovulation.

        Partner with endometriosis.

        History of cancer.

        History of treatment with cytotoxic drugs, irradiation, or sulfasalazopyrine.

        History of cryptorchidism.

        History of mumps orchitis.

        History of vasectomy.

        INCLUSION CRITERIA FERTILE MEN:

        Partner attending Lund University prenatal clinic.

        Age 20-45.

        Partner age less than 40.

        Having fathered one or more pregnancies.

        Having stopped birth control to achieve present pregnancy.

        Having achieved present pregnancy in less than 12 months of unprotected intercourse.

        EXCLUSION CRITERIA FERTILE MEN:

        History of cancer.

        History of treatment with cytotoxic drugs, irradiation, or sulfasalazopyrine.

        History of cryptorchidism.

        History of mumps orchitis.

        Having sought or partner having sought treatment or investigation for fertility.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient description (patient's own words): I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Does the patient match the trial criteria? 0
Clinical trial: Validating the Hum Test (NCT02740322)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18-35

          -  Subjective normal hearing and no previous complaints or history of hearing problems or
             otologic disorders

          -  Subjects will be NYU medical students, NYU resident physicians, or patients from the
             Long Island Cochlear Implant Center

        Exclusion Criteria:

          -  Has not had a URI (assessed by asking patient if they have had fever, cough, sore
             throat, nasal congestion, or runny nose) within one month of study session
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? 0
Clinical trial: Role of Provider-at-Triage on ED Efficiency and Quality of Care (NCT02703701)

Eligibility criteria:
Inclusion Criteria:

        Participants are eligible to participate in the study if they are:

          -  English speaking

          -  Without hemodynamic or respiratory compromise

          -  Do not have a nurse-assigned triage severity score of Emergency Severity Index 1 (most
             severe illness or injury score).

        Exclusion Criteria:

        Participants will be excluded if they are:

          -  Unwilling or unable to sign an informed consent

          -  In police custody

          -  Too ill to participate in study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 110 Years

Patient description (medical language): A 57-year-old man comes to the emergency department due to constipation.  His last bowel movement was 2 days ago. He complains of spending about 30 minutes once attempting to defecate. He also has lower back pain.  There is no history of trauma. The pain is not relieved with over-the-counter pain medications.  His vital signs are within normal limits.  Examination shows low back pain that is worse with back flexion and raising of the legs; it radiates into his left leg.  Pinprick in the perianal area does not cause rapid contraction of the anal sphincter.  The rest of the neurologic examination is normal. He is suspected of Cauda Equina syndrome and referred to a spinal MRI.

Patient description (patient's own words): I'm a 57 year-old-man, and I had to go to the ER because I couldn't go defecate. My last trip to the toilet was 2 days ago, and I tried too many times, during 30 min, to get my poop to get out. I also have terrible lower back pain. The doctor did not notice any trauma. I tried to get the pain away using over-the-counter medications, but it simply did not work! Back in the ER my vitals were normal. My pain was even more intense with back flexion, and when I raised my legs, it radiated into my left leg. The doctor did an anus exam where he had to pinch it and it was not reacting! However the rest of my neurologic exam was normal. The doctor suspects a Cauda Equina syndrome and referred me to a spinal MRI.

Does the patient match the trial criteria? 1