araag2/NLI4PR huggingface dataset:
Clinical trial: Aquamid Reconstruction for Osteoarthritis of the Knee (NCT03067090)

Eligibility criteria:
Inclusion Criteria:

          -  Age > 18 years

          -  WOMAC pain score >/= 5

          -  Kellgren and Lawrence radiographic scoring >/= 1

          -  Signed informed consent form

        Exclusion Criteria:

          -  Other diseases affecting the joints such as rheumatoid arthritis

          -  Actual or recurrent infections requiring intravenous antibiotic treatment within the
             last 30 days or oral antibiotic treatment within the last 14 days before inclusion

          -  Less than 12 weeks since injection of HA or corticosteroids in study-knee joint before
             treatment

          -  Pregnancy or lactation

          -  Not able to comply with the requirements of the study

          -  Previous alloplasty
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? 1
Clinical trial: Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department (NCT02781207)

Eligibility criteria:
Inclusion Criteria:

          -  patients evaluated in the Emergency Department for loss of consciousness

        Exclusion Criteria:

          -  identification of cause of loss of consciousness after initial evaluation;

          -  loss of consciousness classified as high risk syncope.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? 0
Clinical trial: Efficacy of the Standard Days Method of Family Planning (NCT00505609)

Eligibility criteria:
Inclusion Criteria:

          -  Women

          -  Age 18-39

          -  Married or living with stable partner

          -  At least three cycles (four periods) since last birth

          -  Self reported cycles 26-32 days long

          -  Willing to avoid intercourse 12 consecutive days every cycle

          -  Partners willing to collaborate

          -  No known infertility problems

          -  Not at risk for sexually transmitted infections

          -  No contraindications of pregnancy

          -  No use of hormonal contraceptives in three months prior to admission

          -  Desiring to avoid pregnancy for at least one year

        Exclusion Criteria:

          -  Women who have cycles outside of the 26-32 day range

          -  Women/couples not interested in the method

          -  Women who have not yet had 3 regular cycles after childbirth

          -  Women who have used hormonal contraceptives in the previous 3 months

          -  Those women at risk for sexual transmitted infections

          -  Women/couples who cannot manage the fertile days by avoiding intercourse or using a
             barrier method
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 39 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: The Efficacy of Different Doses of Acupuncture in Dysmenorrhea (NCT03881319)

Eligibility criteria:
Inclusion Criteria:

          1. Women within reproductive age (15 to 49 years)

          2. VAS≧4

          3. Women with a history of regular menstrual cycles (28days±7 days)

          4. Self-reported lower abdominal and pelvic, medial anterior thigh pain or low back pain
             associated with the onset of menses and lasting in 72 hours.

        4.Symptoms: dysmenorrhagia, breast pain, dizziness, bloating, cramps, nausea, vomiting,
        diarrhea, headache, fatigue, etc.

        Exclusion Criteria:

          1. Women with irregular menstrual cycles

          2. Women use of an intrauterine contraceptive device (IUCD/IUD)

          3. Women with uncontrolled neurological diseases

          4. Lactation, pregnant women, or those with plans to get pregnant in the coming half year
Female
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.
Subject must be at most 49 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 1
Clinical trial: Regadenoson Stress-MRI to Identify Coronary Artery Disease in Atrial Fibrillation Patients (NCT01710254)

Eligibility criteria:
Inclusion Criteria:

        Patients with confirmed persistent or paroxysmal AF and suspected coronary artery disease
        who will undergo catheterization X-ray angiography

        Exclusion Criteria:

          1. Critically ill patients, patients on ventilators patients with hypotension,
             asthmatics, and other patients whose medical care or safety may be compromised from
             undergoing an MRI examination will be excluded.

          2. Patients with claustrophobia will also be excluded since MRI is conducted in a closed
             environment.

          3. Patients with contraindications to MRI (pacemaker, metal implants).

          4. Pregnant subjects (or women who may become pregnant), minors, and prisoners will be
             excluded from this study.

          5. Subjects are over 60 or have any suspicion of abnormal kidney function (a blood test
             to determine Glomerular filtration rate (GFR) will be performed prior to imaging.
             Subjects with GFR<30 will be excluded from the study. This is standard practice for
             clinical scans in Radiology due to the extremely small but not negligible relationship
             between gadolinium contrast agent and nephrogenic systemic fibrosis in patients with
             severely impaired renal function.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Patient description (medical language): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient description (patient's own words): I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Does the patient match the trial criteria? 1
Clinical trial: Improving Knowledge About Infertility; an Online Educational Tool (NCT01916356)

Eligibility criteria:
Inclusion Criteria:

          -  Women between the ages of 18 and 60 years

          -  Men between the ages of 18 and 60 years

          -  Booking an appointment at the infertility clinic for the first time

          -  Access to a computer with internet connection

          -  For pilot study: students must be in first or second year medical school before
             teaching on infertility

        Exclusion Criteria:

          -  Previous appointment at the infertility clinic/ previous medical specialist counsel
             about infertility

          -  Completion of the study surveys after their appointment at the infertility clinic
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient description (patient's own words): I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Does the patient match the trial criteria? 1
Clinical trial: Combined Scalp and Ear Acupuncture in Patients With Proton Pump Inhibitor- Dependent Gastroesophageal Reflux Disease (NCT04660019)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with gastroesophageal reflux symptoms who have had Reflux esophagitis (Reflux
             esophagitis) diagnosed by endoscopy.

          -  After using PPI, the symptoms can be improved, but the symptoms are still repeated,
             and they need to rely on PPI or antacids for a long time.

        Exclusion Criteria:

          -  Cannot sign consent form

          -  Women who are ready to become pregnant or are pregnant.

          -  Have a history of fainting during acupuncture treatment.

          -  Those using anticoagulants or antiplatelet agents.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 0
Clinical trial: Effect Nitrous Oxide On Acute Postoperative Pain and Opioid Consumption and Chronic Pain After Inguinal Hernia Repair Surgery (NCT01622322)

Eligibility criteria:
Inclusion Criteria:

          -  18 to 65 years old at time of the first procedure

          -  American Society of Anesthesiologists physical status I or II

          -  Inguinal hernia repair surgery undergoing the general anesthesia

        Exclusion Criteria:

          -  Neuropathic disease

          -  Chronic opioid users

          -  Contraindication for Nitrous Oxide receive

          -  Consent will not be obtained patient

          -  Psychiatric disorders

          -  Current or recent drug abuse (within past 6 months).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Comparison Tympanoplasty With Membrane Amniotic and Autologous Fascia (NCT03569969)

Eligibility criteria:
Inclusion Criteria:

        -

        Exclusion Criteria:

          -  Acute Otorrhea / - Cholesteatomas / - Canal stenosis requiring Canaloplasty / -
             Immunosuppressive patients / - Active neoplasm / - Diabetes Mellitus / - Ruptures less
             than one fifth of the eardrum / - Smoking.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? 0
Clinical trial: Hydrocortisone Vs Prednisolone in AI (HYPER-AID) (NCT03608943)

Eligibility criteria:
Inclusion Criteria:

          -  Aged 18 - 85 years

          -  Male or female

          -  Diagnosed with adrenal insufficiency (AI) for over 6 months according to standard
             diagnostic criteria

          -  Established on stable hydrocortisone or prednisolone replacement, dose not altered for
             at least 4 months

          -  Individuals taking other hormone replacements are accepted providing that their
             replacement doses have not altered for at least 3 months;

          -  Individuals who are able and willing to give written informed consent to participate
             in the study

        Exclusion Criteria:

          -  Individuals who are unable to give informed consent

          -  Pregnancy (determined by patients self-reporting pregnancy status)

          -  Patients using the combined oral contraceptive pill
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 33-year-old woman comes to clinic complaining of progressive fatigue, decreased appetite, and 11-lb weight loss in the past 2 months.  She uses levothyroxine because of the previously diagnosed Hashimoto disease. She has no other medical conditions and does not use tobacco, alcohol, or illicit drugs.  Physical examination shows a generalized increase in pigmentation of the skin.  Measurement of serum cortisol before and after administration of exogenous adrenocorticotropic hormone (ACTH) shows no difference in the levels. Stable glucocorticoid replacement therapy starts for her with the diagnosis for primary adrenal insufficiency (Addison disease)

Patient description (patient's own words): I went to the clinic because I was really suffering from fatigue and decreased appetite and I also lost 11 pounds over the past two months. I'm just 33 years old so that's not normal, especially for a woman. I take levothyroxine because I have been diagnosed with Hashimoto disease. I don't have any other medical condition, and I don't smoke I don't drink, and I don't do drugs. They also did my physical examination and they saw that I had an increase in pigmentation of my skin. They measured my cortisol level before and after giving me some ACTH hormone, and the results came back with no difference whatsoever. The doctor told me I have Addison disease and put me under glucocorticoid therapy.

Does the patient match the trial criteria? 0