araag2/NLI4PR huggingface dataset:
Clinical trial: Vibration Response Imaging (VRI) in Management and Evaluation in Patients With Pleural Effusion (NCT00473291)

Eligibility criteria:
Inclusion Criteria:

          -  Able and willing to read, understand, and provide written Informed Consent;

          -  Male or Female in the age range of 18-85 years;

          -  Subject is suspected to have pleural effusion;

          -  Body mass index (BMI) > 21.

        Exclusion Criteria:

          -  Chest wall deformation;

          -  Spine deformation (including severe scoliosis);

          -  Hirsutism;

          -  Potentially contagious skin lesion on the back;

          -  Skin lesion that would interfere with sensor placement;

          -  Cardiac pacemaker or implantable defibrillator;
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? 1
Clinical trial: Increased Calorie Intake to Reverse Energy Deficiency in Exercising Women: Impact on Bone and Menstrual Cyclicity (NCT00392873)

Eligibility criteria:
Inclusion Criteria for Ovulatory Control Volunteers:

          -  18-35 years

          -  BMI 16-25 kg/m2

          -  At least 2 hr/wk of aerobic exercise

          -  Gynecological age >/= 5 years

          -  Weight stable (+/- 2 kg) last 6 months

          -  History of regular menses for 6 months

        Inclusion Criteria for Women with Irregular or Absent Menses:

          -  18-35 years

          -  BMI 16-25 kg/m2

          -  At least 3 hr/wk of aerobic exercise

          -  Gynecological age >/= 5 years

          -  Weight stable (+/- 2 kg) last 6 months

          -  No menses within past 3 months or 6 or less menses in last 12 months

          -  Low to normal bone mass (L1-L4 Z score </=0)

        Exclusion Criteria for all participants:

          -  Hormonal contraceptives in last 6 months

          -  Smoking currently

          -  Current clinical diagnosis of an eating disorder

          -  Use of medications incompatible with measurement of reproductive or metabolic
             hormones, including thyroid medications that may interfere with any of the study
             outcomes.

          -  Dietary habits incompatible with prescribed diet for study

          -  Any metabolic, reproductive or bone disease

          -  Sedentary individuals with less than 120 minutes (2 hrs) of activity per week
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 0
Clinical trial: 24 Hour Esophageal and Electrogastrography to Investigate the Mechanism of Reflux Esophagitis (NCT00154570)

Eligibility criteria:
Inclusion Criteria:

          -  GERD questionnaire with heartburn or acid regurgitation with a frequency at least once
             weekly.

          -  Endoscopic esophagitis.

        Exclusion Criteria:

          -  A history of esophageal, gastric or abdominal surgery.

          -  Gastric or esophageal cancer.

          -  Esophageal varices.

          -  Concomittant severe systemic disease.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 0
Clinical trial: Effect Sildenafil and Estradiiol Valerate on Endometrial Thickness in Infertile Women (NCT03301233)

Eligibility criteria:
Inclusion Criteria:

          1. Patients having ovulatory infertility.

          2. Age: 20-35 years old.

          3. BMI less than 30 kg/m2

        Exclusion Criteria:

          1. Women who have any congenital uterine anomaly (e.g., unicornuate uterus or infantile
             uterus) or acquired deformities of the uterine cavity that interfere with embryo
             implantation (as Asherman Syndrome).

          2. Women who have any tubal factor that relates to infertility (e.g., tubal adhesion or
             previous ectopic pregnancy).

          3. Women who have contraindication for estrogen treatment (e.g., history of stroke, DVT
             and Benign liver disease).

          4. Women who have male factor for infertility (e.g., azoospermia, teratospermia).
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: The Application of Fluorescence Laparoscopy in the Treatment of Adenocarcinoma of the Esophagogastric Junction (NCT03647540)

Eligibility criteria:
Inclusion Criteria:

        - 1. All cases should be diagnosed as adenocarcinoma of the esophagogastric junctionncer by
        histology. The tumor is within 1 cm above or 2 cm below the anatomic cardia. The clinical
        stage is T1-3, Nx, M0 for gastric cancer which can undergo the laparoscopic surgery.

        2. Eastern Cooperative Oncology Group (ECOG) scale 0-2 3. Heart, lung, liver, and kidney
        function can tolerate operation 4. Patients and their families are able to understand and
        be willing to participate in this clinical study and to sign informed consent.

        Exclusion Criteria:

        1. history of stomach malignant disease 2. recent diagnosis of other malignant tumors
        (except for papillary carcinoma of the thyroid gland and basal cell carcinoma of the skin)
        3. patients with obstruction, perforation, bleeding requiring emergency surgery 4. a
        history of abdominal surgery (which makes it difficult to perform laparoscopic procedures),
        severe systemic disease such as diabetes, severe chronic lung disease, cirrhosis, other
        malignant diseases 5. combined stomach multiple carcinomas 6. with a history of serious
        mental illness 7. pregnant or lactating women 8. The researchers believe that the patients
        are unsuitable to participate in the researchers with other cases.

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 0
Clinical trial: Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication (NCT03583931)

Eligibility criteria:
Inclusion Criteria:

          -  18 years old and older

          -  Admitted with pleural effusion that undergoes thoracentesis by medical/pulmonary
             service

          -  Pleural fluid pH <7.3

          -  SICU placed chest tube

          -  Subsequent transfer to SICU

        Exclusion Criteria:

          -  Existing malignancy

          -  Malignant cells from initial pleural fluid sample

          -  End stage liver disease (Child's B or greater)

          -  Coagulopathy

          -  Unable to tolerate surgical procedure

          -  Frank purulent drainage (needs OR regardless)

          -  Recent surgery of abdomen or thorax precluding the use of tPA

          -  Baseline neurologic impairment requiring a proxy for consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? 0
Clinical trial: REAL-LIFE DATA OF CONSTITUTIONAL VON WILLEBRAND DISEASE IN WESTERN FRANCE (HOPSCOTcH-WILL) (NCT03875924)

Eligibility criteria:
Inclusion Criteria:

          -  Constitutional VWD patient, of any severity, with or without inhibitors (according to
             the CRMW criteria*),

          -  Patient included in the research database BERHLINGO

          -  Patient treated or not by desmopressin or VWF/FVIII/by-passing agents available on the
             French market (at baseline)

          -  Patient who agrees to participate in the HOPSCOTcH and followed in one of the 5
             investigator HTC

          -  Patient who are not under guardianship

               -  CRMW criteria for constitutional VWD definition:

        Severe forms: VWF:Ag and VWF:RCo <5 UI/dL VWD 2A or 2M: VWF:RCo/VWF:Ag < 0.7 and/or ratio
        VWF:CB/VWF:Ag < 0.7 VWD 2B: unexplained thrombopenia and/or positive RIPA < 0.8 mg/mL (for
        any value of VWF:RCo/VWF:Ag) VWD 2N: FVIII:C/VWF:Ag < 0.6 and reduced to very reduced
        VWF:FVIIIB VWF:Ag <30 UI/dL (in the absence of every previous criteria)

        Exclusion Criteria:

          -  Patients Under guardianship
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? 1
Clinical trial: The Effectiveness of Kinesio Taping Method for Knee Osteoarthritis. (NCT03076177)

Eligibility criteria:
Inclusion Criteria:

          -  diagnosed (and radiologically verified) I-III stage knee osteoarthritis, has no
             contraindications (exclusion criteria) to participate in research, are willing to
             follow studies protocol and gives informed approval to participate in this research in
             written form.

        Exclusion Criteria:

          -  Rheumatoid arthritis or other systemic rheumatoid disease (LE, sclerodermia,.. etc)

          -  Fragile, very sensitive skin or it's lesions in areas where tapes are to be applied

          -  Inability to do functional tests according study protocol due to very impaired knee
             function or severe comorbidities.

          -  Diagnosed or suspected cancer in areas where tapes to be applied

          -  < than 6 months after intra-articular injections in knee joint

          -  Constant usage of analgesic medicament due to comorbidities

          -  Pregnancy

          -  History of Kinesio Taping method applications in the past

          -  Need for orthotics

          -  Unwillingness not to use local ointments in knee region during participation in study
             period (i.e. 2 months)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? 1
Clinical trial: The Effect of a Structured, Home-based Interview With a Patient on First-year Medical Students' Patient-centredness. (NCT03722810)

Eligibility criteria:
Inclusion Criteria:

          -  Medical students who are in the first year of their studies (their first Bachelor
             year) at the University of Bern, Switzerland.

        Exclusion Criteria:

          -  None
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? 0