araag2/NLI4PR huggingface dataset:
Clinical trial: Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee (NCT00832312)

Eligibility criteria:
Inclusion Criteria:

        - Osteoarthritis of knee

        Exclusion Criteria:

          -  Positive rheumatologic serologic tests

          -  Cognitive impairment

          -  Adjacent osteomyelitis

          -  Bacteremia

          -  Hemarthrosis

          -  Impending (scheduled within days) joint replacement surgery

          -  Infectious arthritis

          -  Joint prosthesis

          -  Osteochondral fracture

          -  Periarticular cellulitis

          -  Poorly controlled diabetes mellitus

          -  Uncontrolled bleeding disorder or coagulopathy.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? 0
Clinical trial: Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients (NCT04155918)

Eligibility criteria:
Key Inclusion Criteria:

          -  History of gout

          -  sUA > 7 mg/dL

          -  Estimated Glomerular Filtration Rate (eGFR) ≥ 60 mL/min/1.73m2

        Key Exclusion Criteria:

          -  Malignancy within 5 years, except for successfully treated basal or squamous cell
             carcinoma of the skin

          -  History of cardiac abnormalities

          -  Active peptic ulcer disease or active liver disease

          -  History of kidney stones

          -  Allergy or intolerance to colchicine, febuxostat, and allopurinol
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? 0
Clinical trial: Chronic Postoperative Pain After Laparoscopic Groin Hernia Repair (NCT04838028)

Eligibility criteria:
Inclusion Criteria:

        All laparoscopic TEP and TAPP repairs that have been registered in the SHR from September
        1, 2012, until November 6, 2019.

        Exclusion Criteria:

          -  Open repairs.

          -  Hernioplasties that were converted from laparoscopic to open surgery.

          -  Age < 15 years.

          -  Patients not having a 10-digit state-assigned Patient Identification Number.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 15 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Treatment of Dilated Blood Vessels on the Cheeks With a New Yellow Laser and a Traditional Green Laser (NCT03472859)

Eligibility criteria:
Inclusion Criteria:

          -  The subjects are required to be Finnish speaking adults with symmetrical facial
             telangiectasia, volunteering to participate in the clinical trial.

          -  The subjects have to have a Fitzpatrick skin phototype I-IV.

        Exclusion Criteria:

          -  pregnancy

          -  lactation

          -  hemophilic condition

          -  Fitzpatrick skin phototype V-VI

          -  drug or alcohol abuse

          -  subjects who are under guardianship

          -  subjects with significant tanning less than 6 weeks prior to the treatment day.

          -  unbalanced basic diseases, such as diabetes, heart disease, cancer etc.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? 1
Clinical trial: How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department (NCT04401241)

Eligibility criteria:
Inclusion Criteria:

          -  patient suspected of COVID19

        Exclusion Criteria:

          -  patient unsuspected of COVID19
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 1
Clinical trial: Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities (NCT03684512)

Eligibility criteria:
Inclusion Criteria:

          -  Mild to moderate IDD (IQ of 74-40).

          -  Sufficient functional ability to understand directions, communicate preferences,
             wants, and needs through spoken language.

          -  Living at home with a parent or guardian who is willing to participate in the
             intervention, with no plans to change this living situation and/or to leave the study
             area in the next 18 mos.

          -  Wireless internet access in the home.

        Exclusion Criteria:

          -  Unable to participate in moderate to vigorous physical activity (MVPA).

          -  Pregnancy during the previous 6 mos., currently lactating, or planned pregnancy in the
             following 18 mos.

          -  Unwilling to be randomized.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 10 Years old.
Subject must be at most 21 Years

Patient description (medical language): A 15-year-old boy with mild intellectual disability is brought to the office by his parents for a routine physical examination.  The boy is going to a school for students with learning disabilities.  The patient was adopted, and his immunizations are up to date.  Review of the patient's medical records is notable for cytogenetic studies that showed a small gap near the tip of the long arm of the X chromosome, which is consistent with fragile X syndrome, an X-linked disorder. The defect is an unstable expansion of trinucleotide repeats (CGG) in the fragile X mental retardation 1 (FMR1) gene, located on the long arm of the X chromosome. He is not using any medications and vital signs are within normal levels. His blood chemistry analysis as bellow:
Blood Chemistry Value      Normal Range     Patient Value
Glucose                    90-120 mg/dl     95 mg/dl
BUN (Blood Urea Nitrogen)  7-24 mg/dl       10 mg/dl
Creatinine                 0.7-1.4 mg/dl    0.8 mg/dl
Calcium                    8.5-10.5 mg/dl   9 mg/dl
Sodium                     134-143 mEq/L    135 mEq/L
Potassium                  3.5-4.5 mEq/L    3.7 mEq/L
Chloride                   95-108 mEq/L     98 mEq/L
CO2                        20-30 mEq/L      25 mEq/L
Blood pH                   7.38-7.42        7. 39

Patient description (patient's own words): My husband and I brought our 15-year-old son to the clinic for his routine exam. My son is going to school for special needs students. We adopted him a few years ago. His vaccinations are up to date. He already passed some chromosome testing and they found that he has a fragile X syndrome. The doctor told us that it comes from repeats in the fragile X chromosome. My son is not using any medication and his blood pressure temperature and breathing were normal during the exam. He also did a blood test. The results came back and showed that his blood sugar urea creatinine calcium sodium potassium chloride CO2 and blood pH were all within the normal range.

Does the patient match the trial criteria? 1
Clinical trial: Pelvic Floor and Sexual Dysfunction in Women With Sjogren's Syndrome (NCT04415710)

Eligibility criteria:
Inclusion Criteria:

          -  being between the ages of 18-65

          -  being a woman,

          -  having sex partner,

          -  no smoking, no alcohol

        Exclusion Criteria:

          -  physical, psychological, cognitive impairment,

          -  having a non-Sjögren additional disease,

          -  malignancy,

          -  pregnancy,

          -  no urogenital disease,

          -  sarcoidosis,

          -  AIDS,

          -  anticholinergic drug use,

          -  had a gynecological or urological operation other than cesarean
Female




Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Treatment of Lateral Epicondylitis: Platelet Rich Plasma Versus Steroid Versus Saline Solution (NCT01109446)

Eligibility criteria:
Inclusion Criteria:

          -  Duration of tennis elbow > 6 months

          -  Doppler activity on ultrasonography

          -  Lateral elbow pain that is maximal over the lateral epicondyle, and increases with
             pressure on the lateral epicondyle, and resisted dorsiflexion and/or middle finger.

        Exclusion Criteria:

          -  Inflammatory disease.

          -  Fibromyalgia.

          -  Pain in hand or shoulder/neck in the same arm as being treated.

          -  Anticoagulation treatment.

          -  Wounds around the elbow.

          -  Treatment with steroids within the last 3 months.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? 0
Clinical trial: Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome (NCT02715323)

Eligibility criteria:
Inclusion criteria:

        Recruitment inclusion criteria for Systemic diseases participants:

        1. Clinically diagnosed with Primary Sjogren's Syndrome, Rheumatoid Arthritis or Systemic
        Lupus Erythematosus.

        Recruitment inclusion criteria for controls:

          1. NO Dry eye or severe Meibomian Gland Disease

          2. NO current or recent (< 6 months) conjunctivitis, keratitis, uveitis or other
             inflammatory condition affecting eye

          3. NO recent ocular surgery or LASIK (< 6 months)

          4. Frequency of dry eye symptoms is < once/week (burning, tearing, itching, foreign body
             sensation, transient blurring improved by blinking)

          5. NO contact lens wear for the past 1 week

          6. NO systemic conditions of Diabetes Mellitus, Rheumatoid Arthritis, Systemic Lupus
             Erythematosus

          7. Bulbar redness is < 1.5 grading

        Exclusion Criteria:

          1. Known history of thyroid disorders (diagnosed by physician)

          2. No ocular surgery within the last 3 months and LASIK within 1 year.

          3. Ocular surface diseases such as pterygium, or obvious lid/orbital disease with
             lagophthalmos.

          4. Any other specified reason as determined by clinical investigator.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 21 Years old.
Subject must be at most 99 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism (NCT01107067)

Eligibility criteria:
Inclusion Criteria:

          -  Volunteers patients with hypogonadism

        Exclusion Criteria:

          -  Coronary heart disease

          -  Other pituitary/hypothalamic disorders or other non-hypogonadism diseases

          -  None was receiving vitamins, lipid-lowering drugs, or other medications known to
             interfere with PON1 activity, lipid profile, or gonadal function
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 25 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 0