araag2/NLI4PR huggingface dataset:
Clinical trial: Comparison of Conservative Methods for the Treatment of Lateral Epicondylitis: A Randomized, Prospective Study (NCT01897259)

Eligibility criteria:
Inclusion Criteria:

          -  pain over the lateral epicondyle (via palpation over the lateral epicondyle, resisted
             wrist extension, resisted finger extension of the middle finger) for less than
             six-months duration prior to enrollment

          -  conservative treatment of tennis elbow is recommended as standard of care treatment

          -  over the age of 18 and under the age of 65

          -  ability to give informed consent

        Exclusion Criteria:

          -  treatment by a health care profession (MD, physicians assistnat, therapist, or nurse
             practitioner) within the previous 6 months for tennis elbow

          -  congenital deformities, tendon ruptures, or fractures of the elbow within the previous
             12 months

          -  immobility casts or splints within the last 6 months for tennis elbow

          -  co-existing elbow diagnosis (i.e. osteoarthritis or instability)

          -  pregnant women, women trying to get pregnant, or breastfeeding women

          -  under the age of 18 or over the age of 65
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? 0
Clinical trial: Oracea Soolantra Association in Participants With Severe Rosacea (NCT03075891)

Eligibility criteria:
Inclusion Criteria:

          -  Male or female subject age ≥ 18 years or older;

          -  Subject with a minimum of 20 but not more than 70 inflammatory lesions (papules and
             pustules) of rosacea on the face at Baseline visit;

          -  Subject with severe rosacea with papulopustular lesions (according to the
             Investigator's Global Assessment (IGA) score rated 4);

          -  Female subjects of childbearing potential with a negative urine pregnancy test (UPT);

          -  Female subjects of childbearing potential must practice a highly effective method of
             contraception during the study.

        Exclusion Criteria:

          -  Subjects with particular forms of rosacea or other concomitant facial dermatoses that
             may be confounded with rosacea;

          -  Subjects with more than 2 nodules of rosacea on the face;

          -  Subjects with any uncontrolled chronic or serious disease or medical condition that
             may either interfere with the interpretation of the clinical trial results, or with
             optimal participation in the study or would present a significant risk to the subject;

          -  Subjects with known or suspected allergies or sensitivities to any component of the
             investigational and non-investigational products, including the active ingredients
             doxycycline and ivermectin.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? 1
Clinical trial: Finhyst 2006: Study on Morbidity of Hysterectomies in Finland (NCT00744172)

Eligibility criteria:
Inclusion Criteria:

          -  Bening indications for hysterectomy

        Exclusion Criteria:

          -  Malignant indications for hysterectomy

          -  Postpartum hysterectomy
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 1
Clinical trial: Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome (NCT00001456)

Eligibility criteria:
-  INCLUSION CRITERIA:

        Subjects with HPS age 1-80 years are eligible to enroll in this protocol.

        The diagnosis of HPS is based upon a paucity or deficiency of platelet dense bodies on
        whole mount electron microscopy or the identification of pathogenic variants in HPS genes
        by genetic testing. Some subjects who have not been diagnosed with HPS may be admitted to
        the protocol based upon the presence of albinism and a platelet storage pool deficiency.

        Most female subjects who participate in the Obstetrics/Gynecology Questionnaire will be
        enrolled in the protocol.

        Subjects with HPS or family members who are their caregivers participating in the HPS
        Symptom Questionnaire will be at least 18 years of age. These subjects will enroll in the
        protocol and will provide written consent.

        EXCLUSION CRITERIA:

        Infants under age one year are excluded because there is generally no urgency for a very
        early diagnosis and care is more readily provided to older infants at the Clinical Center.

        Pregnant women and adults who are unable to provide consent are excluded.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 1 Year old.
Subject must be at most 80 Years

Patient description (medical language): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient description (patient's own words): I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Does the patient match the trial criteria? 1
Clinical trial: Clinical Study on Post Evaluation After Listing of Qizhi Weitong Granules (NCT03149393)

Eligibility criteria:
Inclusion Criteria:

          1. Metting the diagnostic criteria of functional dyspepsia in Rome IV.

          2. The subjects were informed, and the subjects voluntarily signed informed consent.

          3. The subjects have reading ability.

        Exclusion Criteria:

          1. Patients suffering from gastric ulcer, gastroscopy see bleeding and mucosal erosion,
             pathological examination showed atrophy of gastric mucosa, intestinal metaplasia or
             dysplasia.

          2. Patients with Hp infection positive.

          3. Patients with gastroesophageal reflux disease.

          4. Patients with digestive system organic lesions.

          5. The patient had a history of stomach or abdominal surgery.

          6. Patients had taken the relevant drugs in the past 2 weeks.

          7. Patients suffering from severe illness affecting survival.

          8. Pregnant or lactating women.

          9. Participating in clinical trials of other drugs.

         10. Long term using of sedative hypnotics.

         11. Suspected or true alcohol, drug abuse history.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 0
Clinical trial: Dräger COVID-19 Antigen Test Clinical Performance Study (NCT04698993)

Eligibility criteria:
Inclusion Criteria:

          -  Participants must require SARS-CoV-2 testing for the following reasons:

               -  COVID-19 symptoms (Fever, cough and/or sore throat, fatigue/ general feeling of
                  weakness, loss of sense of smell and/or taste, shortness of breath, muscle
                  stiffness/ body aches, head cold/ running nose, etc.) on the day of testing, or

               -  Known or suspected exposure to SARS-CoV-2 (contact persons etc.), or

               -  Member of a group of high risk of exposure such as healthcare workers etc., or

               -  Require screening for any other reason, e.g. doctor's orders, hygiene directive
                  etc.

          -  Participant must be of legal age and must be able to understand the procedure and
             letter of consent.

        Exclusion Criteria:

          -  Patients younger than 18 years old are excluded from the study.

          -  Pregnant or breastfeeding patients are excluded from the study.

          -  Patients unable to provide written informed consent are excluded.

          -  Patients with bleeding disorder are excluded from the study as a precaution.

          -  Hospitalized patients/inpatients are excluded.

          -  Application of nasal spray within 15 min prior to testing.

          -  Participants with symptoms on the day of testing are excluded, if any of their
             symptoms started more than 14 days prior to testing.

          -  Asymptomatic participants are excluded, if they experienced any symptoms in the 14
             days prior to testing.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 1
Clinical trial: P75NTR, Diagnostic Biomarker for Alzheimer's Disease: Quantification Study in Cerebrospinal Fluid (NCT02946710)

Eligibility criteria:
Inclusion Criteria:

          -  patients with AD

          -  patients with MCI due to AD,

          -  patients with frontotemporal dementia

          -  patients with non-neurodegenerative dementia, according to DSM-V and updated National
             Institute on Aging (NIA) recommendations

        Exclusion Criteria:

          -  patients with Parkinson disease or Lewy body dementia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? 1
Clinical trial: Cushing´s Disease Epidemiology in Sweden (NCT02350153)

Eligibility criteria:
Inclusion Criteria:

          -  All patients registered with Cushing's Disease in Sweden since 1987 in the statistical
             database for in- and out-patients, at the Swedish National Board of Health and Welfare
             will be included in the study.

        Exclusion Criteria:

          -  No
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old man comes to the office due to weight gain and fatigue.  He is not able to lift heavy objects or climb stairs. Family history is positive for DM type 2 and HTN in his father.  Blood pressure is 165/90 mm Hg and pulse is 85/min.  On physical examination, there is symmetric proximal muscle weakness of the upper and lower extremities.  Fasting plasma glucose level is 138 mg/dL and 24-hour urinary cortisol is twice the upper normal limit.  Further evaluation reveals that high-dose, but not low-dose, dexamethasone suppresses serum cortisol levels.  Serum ACTH levels are high-normal. This patient's findings are consistent with endogenous Cushing Syndrome.

Patient description (patient's own words): I'm a 47-year-old man. I went to the clinic because I had been gaining weight and had increased fatigue over the past few weeks. I was not able to lift heavy objects or even climb the stairs. My dad was diagnosed with type 2 diabetes and high blood pressure. During the exam, they took my blood pressure, which was 165/90 mm Hg, and my pulse was 85/min. They found out that I have weaknesses in both of my arms and legs. I also did a blood test on an empty stomach, and I had a glucose level of 138 mg/dL, and twice the upper normal limit of cortisol. I had high-normal levels of ACTH. The doctor said I suffer from endogenous Cushing Syndrome.

Does the patient match the trial criteria? 1
Clinical trial: Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk (NCT03076034)

Eligibility criteria:
Inclusion Criteria:

          -  Women with hip and wrist fractures within 2 weeks of presentation

          -  Non-fracture controls

        Exclusion Criteria:

          -  Unable to undergo BMD by DXA or high-resolution peripheral quantitative computed
             tomography (HR-pQCT)

          -  History of skeletal metastasis, primary hyperparathyroidism, Paget's disease, multiple
             myeloma

          -  Treatment with bisphosphonate, estrogen (within previous 3 years), teriparatide
             therapy, calcitonin, selective estrogen receptor modulator (SERMs,within previous 3
             years)

          -  Use of glucocorticoids continuously for more than 3 months, use of anticonvulsants

          -  Prior fracture in adulthood (>age 18) for healthy controls

        Amendment to protocol added Arm 2, to include males >50 years with otherwise similar
        eligibility criteria.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 100 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? 0