araag2/NLI4PR huggingface dataset:
Clinical trial: Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET) (NCT04032470)

Eligibility criteria:
Inclusion Criteria:

          -  Meets criteria established in the locally applicable Directions for Use (DFU) for
             Essential Tremor

          -  Is at least 18 years old

        Exclusion Criteria:

          -  Meets any contraindication in locally applicable Directions for Use
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? 1
Clinical trial: Comparative Study of the Magnetically Guided Capsule Endoscopy Versus High Definition Gastroscopy (NCT01555840)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with gastric focal lesions (Group A)

          -  Patients with gastric symptoms and indicated for Upper GI endoscopy (Group B)

          -  Age of 18 years to 75 years"

        Exclusion Criteria:

          -  Patients with dysphagia or symptoms of gastric outlet obstruction

          -  Patients with suspected or known intestinal stenoses

          -  Overt GI bleeding

          -  Known large and obstructing tumors of the upper GI tract

          -  Patients after upper GI surgery or abdominal surgery altering GI anatomy

          -  Patients under full anticoagulation

          -  Patient in poor general condition (ASA III/IV)

          -  Patients with claustrophobia

          -  Patients using equipment that may be affected by radio transmission

          -  Patients using equipment that may be affected by magnetic field

          -  Pregnancy or suspected pregnancy "
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1
Clinical trial: A Direct-to-patient Intervention to Increase Rates of Osteoporosis Care (NCT01907269)

Eligibility criteria:
Inclusion Criteria:

          -  Self-reported history of fracture

        Exclusion Criteria:

          -  Self-reported current prescription osteoporosis treatment
Female
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 1
Clinical trial: A Modified Technique for Laparoscopic Subtotal Hysterectomy (NCT02328274)

Eligibility criteria:
Inclusion Criteria:

          -  patients aged 20 years old and above with symtomatic uterine myomas or adenomyosis

          -  complete medical record

        Exclusion Criteria:

          -  patients aged below 20 years old

          -  uterine malignancy

          -  incomplete medical record
Female
Accepts Healthy Volunteers
Subject must be at least 20 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 1
Clinical trial: Microbiome and Endometrial Receptivity in Obese Infertile Women (NCT03493529)

Eligibility criteria:
Inclusion Criteria:

          -  Infertile patients undergoing artificial cycle with HRT.

          -  Normal uterus confirmed by ultrasound (absence of uterine pathology such as submucosal
             or intramural myomas> 4 cm that deform cavity, endometrial polyps or Müllerian
             anomalies, or adnexal as communicating hydrosalpinx).

          -  Negative serological tests for HIV, HBV, HCV, RPR

        Exclusion Criteria:

          -  Taking prescribed antibiotics or using IUDs or contraceptives 3 months prior to taking
             the sample. NOTE: Patients who have taken prophylactic antibiotics for ovarian
             puncture may be included at least 1 month before taking the sample.

          -  Age> 45 years

          -  Uncorrected uterine pathology, uncorrected hydrosalpinx

          -  Recurrent miscarriage (≥2 spontaneous abortions) or failure of implantation (transfer
             of 6 embryos in day 3 or 4 blastocysts in a cycle of IVF or donation of oocytes
             without gestation)

          -  Existence of serious or uncontrolled bacterial, fungal or viral infections that, in
             the opinion of the principal investigator, could interfere with the participation of
             the patient in the study or in the evaluation of the results of the study.

          -  Any disease or medical condition that is unstable or could endanger the patient's
             safety and compliance in the study.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 44 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Efficacy of Dicopeg Junior in Comparison With Lactulose for the Treatment of Functional Constipation in Children Aged 6 Months to 6 Years. (NCT03177434)

Eligibility criteria:
Inclusion Criteria:

          1. Children aged 6 months - 6 years

          2. Diagnosis of functional constipation according to the Rome III criteria

          3. Patients newly recognized or ineffectively treated

          4. Parental consent for their child's participation in the study and the way they are
             treatment for the duration of the study

        Exclusion Criteria:

          1. Well-known organic cause constipation (eg. an underactive thyroid, Hirschprung
             disease, cystic fibrosis).

          2. Anatomical abnormality of the digestive tract.

          3. Status after gastrointestinal surgery

          4. Parents disagree to participate in the study

          5. Intolerance of lactulose or polyethylene glycols in an interview

          6. Comorbidities that may significantly affect the treatment outcome: food allergy,
             celiac disease, CNS disease, lactose intolerance or other disaccharide bacterial
             overgrowth
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 6 Years

Patient description (medical language): A 7-month-old boy is brought to emergency by his parents due to irritability and inability to defecate for the past 3 days.  The patient has had constipation and discomfort with bowel movements since birth.  His symptoms worsened after eating semi-solid foods.  Vital signs are normal.  Abdominal examination shows distension and tenderness to palpation with presence of bowel sounds.  Xray with barium shows a narrow rectum and rectosigmoid area.  The rest of the colon proximal to this segment is dilated. Digital rectal exam revealed burst of feces out of the anus. The biopsy showed absence of submucosal ganglia in the last segment of the large intestine.

Patient description (patient's own words): My baby boy just turned 7 months old but my wife and I cannot get a hold of him! He has not been able to poop for 3 days! My poor little thing has been having constipation and bowel problems since birth. But since he ate some semi-solid food it has just been worse! The doctor said his vitals are normal but his belly is tense and tender with his bowels making noise. They did an X-ray and found out that he had a narrow rectum. His colon is dilated. They also performed a touch rectal exam and he could finally poop! The biopsy revealed that there is no submucosal ganglia in his large intestine.

Does the patient match the trial criteria? 0
Clinical trial: Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout (NCT00111657)

Eligibility criteria:
Inclusion Criteria:

          -  Age >18 years

          -  Symptomatic gout

          -  Serum uric acid >7 mg/dL

          -  Intolerance of, or inadequate response to, conventional therapy for gout

          -  Women of childbearing potential must have a negative serum pregnancy test and must use
             an approved birth control method

        Exclusion Criteria:

          -  End stage renal failure that requires dialysis

          -  Concurrent use of uric-acid lowering agents

          -  Glucose-6-phosphate dehydrogenase (G6PD) deficiency

          -  A history of anaphylactic reaction to a recombinant protein

          -  Concurrent use of immunosuppressive therapy (except as needed for prevention of
             rejection of a transplanted organ, or prednisone at 10 mg a day or less for treatment
             of gout flares)

          -  A medical or psychological condition which, in the opinion of the investigator, might
             create undue risk to the subject
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient description (patient's own words): I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Does the patient match the trial criteria? 0
Clinical trial: A Study for Teriparatide in Severe Osteoporosis (NCT00696644)

Eligibility criteria:
Inclusion Criteria:

          -  Postmenopausal women and men older than 21 years affected by severe osteoporosis with
             an incidental vertebral or hip fracture during treatment with an antiresorptive, or
             having 3 or more severe vertebral fractures or having 2 severe vertebral fractures and
             an historical hip fracture.

        Exclusion Criteria:

          -  Any contraindication for the use of antiosteoporotic drug

          -  Premenopausal women or men younger than 21 years
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 0
Clinical trial: Treating Hypertension With Breath Control (NCT01285193)

Eligibility criteria:
Inclusion Criteria:

          -  Above 18 years old

          -  Patients with essential hypertension

          -  Systolic BP from 140 to 159 mm Hg

          -  Diastolic BP from 90 to 99 mm Hg

          -  On hypertensive medication for at least 3 months before the study

          -  Hypertensive medication unchanged during the 3 months before the study

          -  Patients able to fill in a log sheet

        Exclusion Criteria:

          -  ischaemic heart disease

          -  congestive heart failure

          -  cardiac arrhythmias

          -  renal failure

          -  diabetes mellitus

          -  previous stroke

          -  major organ failure

          -  cigarette smoking

          -  respiratory diseases

          -  psychiatric disorders

          -  severe obesity (BMI >35 kg/m2)

          -  hearing impairment

          -  unable to operate a CD player or do not have access to a CD player

          -  arm circumference <22 cm. or >42 cm.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? 0
Clinical trial: Spectroscopy From Duodenum (NCT01753479)

Eligibility criteria:
Inclusion Criteria:

          -  Common inclusion criterion

               -  Age is 18 years or older.

               -  Informed consent was obtained.

               -  Inclusion criterion for normal cohort

               -  An upper GI endoscopy is scheduled to check upper abdominal symptoms.

               -  No findings of pancreatic disorder as documented by CT or MRI or EUS

          -  Inclusion criterion for PC suspicious cohort * A EUS or ERCP is scheduled to suspected
             pancreatic disorder.

        Exclusion Criteria:

          -  Common exclusion criterion

               -  Severe cardiac disease

               -  Severe respiratory disease

               -  Bleeding disorders

               -  Pregnancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1