araag2/NLI4PR huggingface dataset:
Clinical trial: Retrospective Chart Review to Evaluate Safety and Tolerability of ADVATE Among Previously Untreated Patients in China With Moderate to Severe Hemophilia A (NCT02634723)

Eligibility criteria:
Inclusion Criteria:

          1. Previously untreated patient (PUP) in China with moderate to severe hemophilia A.

          2. Investigator prescribed ADVATE as the predominant therapeutic agent for the management
             of hemophilia A

          3. Informed consent form from patient and/or legal representative will need to be signed
             per local regulation

        Exclusion Criteria:

          1. Presence of an inherited or acquired hemostatic defect other than hemophilia A, and
             any other clinically significant chronic disease

          2. Participants who participated in another investigational FVIII drug study, or had
             participated in any clinical study involving an investigational FVIII drug during the
             course of the observation period
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 1
Clinical trial: Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea (NCT01016782)

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of rosacea

          -  Good health with the exception of rosacea

          -  Papsules and pustules minimum and maximum requirements

        Exclusion Criteria:

          -  Subjects who are pregnant, nursing, or planning a pregnancy within the study
             participation period.

          -  Subjects who have any systemic or dermatological disorders with the exception of
             rosacea
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient description (patient's own words): I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Does the patient match the trial criteria? 1
Clinical trial: Metabolic Syndrome Criteria and the Effect of Testosterone Treatment in Young Men With Hypogonadism (NCT01160341)

Eligibility criteria:
Inclusion Criteria:

          -  Men

          -  Congenital hypogonadism

          -  Treatment Naive

        Exclusion Criteria:

          -  Previous history of androgen replacement

          -  Hypertension

          -  Diabetes mellitus
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 26 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 1
Clinical trial: Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment (NCT01529242)

Eligibility criteria:
Inclusion Criteria:

          -  Consent of the patient or legal guardian;

          -  Clinical diagnosis of acute cutaneous rash defined by the presence of erythematous
             papules on healthy skin, different sizes, itchy and fleeting

          -  Children aged between 2 and 11 years and 11 months (up to 30 kg);

        Exclusion Criteria:

          -  Participation in clinical trial in 30 days prior to study entry;

          -  Patients with history of hypersensitivity to desloratadine or prednisolone or with
             corticosteroids use contraindications ;

          -  Patients with any clinically significant disease other than cutaneous rash including
             hematopoietic, cardiovascular, renal, neurological, psychiatric or autoimmune
             disorders;

          -  Patients on treatment with monoamine oxidase inhibitors (MAOIs);

          -  Patients diagnosed with other dermatoses
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 11 Years

Patient description (medical language): A 2-year-old boy is brought to the office by his parents due to a rash that started 1 week ago.  A similar red, itchy rash on the cheeks, trunk, and arms has occurred intermittently since infancy.  The patient has had a few upper respiratory infections but no major illnesses.  Vaccinations are up to date, and he takes no medications. He is on a balanced diet, and he is healthy in appearance.  Vital signs and milestone examination are within normal limits.  Similar findings are observed on the cheeks and proximal upper extremities.  The diaper area is clear, and no mucosal lesions are present.

Patient description (patient's own words): I just brought my two-year-old son to the doctor's office because he had a rash for like one week. His rash was on the cheeks, the trunk, and his arms. He already had this before, and it keeps coming back from time to time to time. In the past, he had some respiratory infections but he has never been this sick. His vaccinations are up to date, and he doesn't take any medication. He's healthy with a nice diet. The doctor told me his vitals and milestone examinations were normal. The doctor also said there was a rash around the cheek and the upper part of his arms. The diaper area is okay, and there are no lesions.

Does the patient match the trial criteria? 1
Clinical trial: Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes (NCT03665779)

Eligibility criteria:
Inclusion Criteria:

          -  Singleton pregnancy.

          -  Cephalic presentation.

          -  Bishop score < or = 6.

          -  Average size of the fetus.

          -  Adequate pelvic dimensions.

          -  Prelabour rupture of membranes.

          -  Term or post-term pregnancies with an indication for labor induction either maternal
             or fetal.

        Exclusion Criteria:

          -  Previous uterine scar (e.g. caesarian delivery or unknown uterine incision , previous
             hysterotomy or myomectomy of the uterine corpus involving entry of the uterine cavity
             or extensive myometrial dissection, previous uterine rupture)

          -  Patients with regular uterine contractions.

          -  Malpresentation.

          -  Multifetal gesta1tion.

          -  Established fetal distress ( e.g. thick meconium stained liguor or non reassuring CTG
             changes)

          -  Indication for CS, e.g. Major degree of cephalopelvic disproportion and fetal
             macrosomia.

          -  Placenta previa or vasa previa.

          -  Active genital herpes infection.

          -  Severe maternal illness (e.g. severe preeclampsia).

          -  Laboratory and clinical sign of chorioamnionitis.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients? (NCT00032448)

Eligibility criteria:
Inclusion Criteria:

        Men with inguinal hernia.

        Exclusion Criteria:
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Genotype and Susceptibility to COVID-19 (NCT04799834)

Eligibility criteria:
Inclusion Criteria:

        - Age > 18 years

        Exclusion Criteria:

        None
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 1
Clinical trial: Testing of a New Scale Measuring Medical Outcomes of Dysphagia (MOD) in Adult Patients With Swallowing Disorders (NCT01419886)

Eligibility criteria:
Inclusion Criteria:

          -  Adult (18+ years)

          -  Any disease etiology, including but not limited to: previous or current diagnosis of
             head and neck cancer (treatment may include surgery, radiation or chemotherapy, or a
             combination of more than one), stroke, cervical spine abnormality, brain tumour,
             cardiovascular surgery, and Parkinson's disease

          -  Current diagnosis of dysphagia, as determined by a speech language pathologist

          -  English-speaking

        Exclusion Criteria:

          -  No dysphagia

          -  Cognitive impairment

          -  Limited fluency in English
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient description (patient's own words): I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Does the patient match the trial criteria? 1
Clinical trial: Effect of Proton Pump Inhibitor and Mosapride on Acid Pocket in Gastroesophageal Reflux Disease (NCT02984930)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with diagnosed GERD(gastro-esophageal reflux disease), defined by the
             presence of oesophagitis obtained during a previous upper endoscopy or typical GERD
             symptoms(heartburn, acid reflux).

        Exclusion Criteria:

          -  who had organic gastrointestinal disease including inflammatory bowel disease, cancer
             and ulcer

          -  who took drugs which could affect evaluation of the treatment; other PPIs, H2RAs(H2
             receptor antagonists), prokinetics,mucosal protective agents, antacids, cholinergic
             and anticholinergic agents, and antidepressants for at least 4 weeks prior to study
             start

          -  who had severe systemic diseases including hepatic and nephrotic disease

          -  who had previous gastrectomy history

          -  who was in state of pregnancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 1
Clinical trial: Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair (NCT01069055)

Eligibility criteria:
Inclusion Criteria:

          -  inguinal hernia

          -  unilateral hernia

          -  general anesthesia

          -  elective repair

        Exclusion Criteria:

          -  drug allergy

          -  bilateral hernia

          -  local anesthesia

          -  local blockade

          -  regional anesthesia

          -  emergency surgery

          -  complicated hernia

          -  recurrent hernia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Promoting CSD500 Use Among Women in Established Relationships (NCT02934620)

Eligibility criteria:
Inclusion Criteria (for women):

          -  Not currently using a modern contraceptive method other than condoms or intending to
             start using a modern contraceptive method other than condoms in the next 6 months;

          -  Willing to use assigned study condoms as the sole method of contraception for the next
             six months;

          -  Not breastfeeding;

          -  Not known to be pregnant;

          -  Want to avoid pregnancy for at least the next six months; and

          -  Be in a monogamous relationship for at least the past six months with her current male
             partner.

        Exclusion Criteria (for couples):

        Couples are ineligible for study participation if either person in the couple is known to
        be HIV-positive or has any of the following contraindications to CSD500 use:

          -  History of low blood pressure or heart condition;

          -  Current use of medication for anemia, blood pressure, erectile dysfunction, migraines,
             headaches or glaucoma;

          -  Inflamed or broken skin that the condom could come into contact with; or

          -  Latex allergy or sensitivity.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? 0