araag2/NLI4PR huggingface dataset:
Clinical trial: Long Term Incidence and Effect of de Novo GERD After Laparoscopic Sleeve Gastrectomy in Chinese Population (NCT04237857)

Eligibility criteria:
Inclusion Criteria:

          -  Chinese patients who received laparoscopic sleeve gastrectomy at Prince of Wales
             Hospital, The Chinese University of Hong Kong

          -  SG has been performed more than 36 months

          -  Patient received preoperative OGD and GI symptom assessment with C-GIQLI questionnaire

          -  Willing and able to consent to the study

        Exclusion Criteria:

          -  Revisional surgery

          -  Concomitant surgeries (except hiatal repair/ cholecystectomy)

          -  Mentally incompetent patients or patients less than 18 years old

          -  Pregnant patients

          -  Inmates

          -  Unable/unwilling to consent to the study

          -  Unable/unwilling to undergo follow-up assessments
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 0
Clinical trial: Observational Study on the Use of NovoSeven® for Haemostatic Treatment of Bleeding Episodes in Patients With Acquired Haemophilia (NCT01285089)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosed with acquired haemophilia

          -  Treated with activated recombinant human factor VII as first line treatment

          -  Treated with activated recombinant human factor VII after January 2011

        Exclusion Criteria:

          -  Patients with first diagnosis before january 2010 and having a relapse after january
             2011

          -  Known hypersensitivity to NovoSeven®, or to mouse, hamster or bovine protein
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0
Clinical trial: Resting Postural Tremor in Multiple Sclerosis (NCT04405479)

Eligibility criteria:
Inclusion Criteria:

        Group 1:

          -  Definite diagnosis of MS

          -  prevailed motor deficit of upper extremities, but without visible tremor

          -  stable clinical status in the preceding 3 months

          -  Expanded Disability Status Scale score (EDSS) ≥ 2 ≤ 7.5, and

          -  no corticosteroid therapy in the preceding month

        Group 2:

          -  Healthy volunteers in the age of 20-70 years will be employed

          -  There will be defined as persons without any neurological disease diagnose at the time
             of the measurement.

        Exclusion Criteria (both groups):

        Patients with factors disturbing mobility (e.g. stroke, pregnancy, fractures) were excluded
        from the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? 0
Clinical trial: Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial (NCT00563329)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 or above

          -  Ethnic Chinese male or female

          -  Smokes at least 2 cigarettes per day

          -  Have no intention to quit in the near future

          -  Intends to reduce smoking in the next 7 days

          -  Has no contraindication to NRT

        Exclusion Criteria:

          -  Subjects who are psychologically or physically unable to communicate

          -  Children and teenagers (age below 18)

          -  Pregnant or intention to become pregnant within the next 6 months

          -  Those on regular psychotropic medications and in the presence of any serious health
             problems that may make them unsuitable for using NRT, such as recent stroke,
             palpitation, or other life threatening conditions
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? 0
Clinical trial: The Effect of Kinesio Taping on Wrist Flexor Sensorimotor Control in Healthy People (NCT03909880)

Eligibility criteria:
Inclusion Criteria:

        1. Healthy people who are 20-40 years old

        Exclusion Criteria:

          1. Have irreversible injury on forearm, wrist or hand

          2. Feel pain or any uncomfortable symptom on forearm, wrist or hand

          3. Muscular disease on upper extremity in 6 months

          4. Impaired sensation

          5. Allergy

          6. Neurological disease
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? 0
Clinical trial: Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study (NCT01556360)

Eligibility criteria:
Inclusion Criteria:

          -  Patients between 18 and 80 years

          -  C282 homozygosity

        Exclusion Criteria:

          -  corticosteroids during the last 3 months

          -  following treatments during the last 6 months : anabolic steroids, growth hormone,
             hormone therapy for menopause, tibolone, raloxifene.

          -  following treatments during inclusion or in the last 6 month : teriparatide,
             parathormone, fluor, strontium ranelate, biphosphonate.

          -  cancer or evolutionary hemopathy (including monoclonal gammopathy)

          -  pregnancy at inclusion time

          -  treated osteoporosis

          -  patient in wich follow up seems hard

          -  inclusion in another study incompatible with this one
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 51-year-old man comes to the office complaining of fatigue and some sexual problems including lack of libido. The patient doesn't smoke or use any illicit drug.  Blood pressure is 120/80 mm Hg and pulse is 70/min.  Oxygen saturation is 99% on room air.  BMI is 24 kg/m2.  Skin examination shows increased pigmentation. Genotype testing is consistent with homozygosity for the C282Y mutation. Laboratory study shows transferrin saturation of 55% and serum ferritin of 550 μg/L. He is diagnosed as a case of hemochromatosis.

Patient description (patient's own words): I am 51 years old and I just came back from the doctor's office. I'm sick and tired of being that exhausted, reaching the point where me and my lovely wife are not touching each other anymore! I'm not smoking or doing drugs! My blood pressure was 120/80 mm Hg, and pulse was 70/min and my oxygen saturation 99%. My BMI is 24. My skin also turned a bit darker lately. He tested my genes and told me that I have a mutation of the C282Y gene. I also did lab tests where my transferrin saturation was 55% and serum ferritin was 550  μg/L. The doctor diagnosed me with iron overload.

Does the patient match the trial criteria? 1
Clinical trial: A Study to Test the Impact of an Improved Chulha on Respiratory Health of Women and Children in Indian Slums (NCT02821650)

Eligibility criteria:
Inclusion Criteria:

          -  Woman ≥18 years who cooked more than 50% of the meals during the past 30 days (primary
             cook) and one child per household (0-5 years) will be included

          -  Both households with and without children will be included

          -  Women/mothers who are capable of being interviewed

          -  Will not migrate in the upcoming 2 months as far as the participants can predict

          -  Households cooking solely with traditional stove (chulha) or a combination of a
             traditional stove and a kerosene/diesel stove will be included

        Exclusion Criteria:

          -  Households with a cooking area outside the house will be excluded

          -  Persons who are seriously ill will be excluded from the study
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? 1
Clinical trial: Music in the Emergency Department (ED): Phase II (NCT02363179)

Eligibility criteria:
Inclusion Criteria:

          -  Language: english

          -  Cognitive skill/education: grade 2 reading level or above

        Exclusion Criteria:

          -  Language: Non-english speaking

          -  Age: Less than 18

          -  Cognitive skill/education: lower than grade 2 reading level
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? 1
Clinical trial: Endometrial Effects of Sildenafil in Frozen-Thawed Cycles in Women With Thin Endometrium (NCT04283435)

Eligibility criteria:
Inclusion Criteria:

          -  Women (25 -40 years) undergoing IVF frozen-Thawed cycles and known to have good
             quality embryos.

          -  previous thin endometrium (< 8mm on at least 3 previous cycles) with normal
             Hysteroscopy findings

        Exclusion Criteria:

          -  women less than 25 years old or more than 40 years old.

          -  abnormal hysteroscopic findings.

          -  women with congenital uterine anomalies.

          -  History of previous uterine surgery

          -  Any contraindication to Sildenafil as Previous history of cardiac disease or stroke.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 1
Clinical trial: Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI (NCT00539240)

Eligibility criteria:
Inclusion Criteria:

          -  Currently being treated with a PPI, but continue to experience GERD symptoms (such as
             heartburn) at least 2 times per week.

        Exclusion Criteria:

          -  Known allergy or intolerance to TCA

          -  History of serious arrhythmia or use of anti-arrhythmics

          -  History of seizures

          -  Subjects with significant co-morbidity, e.g., cardiovascular, respiratory, urogenital,
             renal, gastrointestinal, hepatic, hematological, endocrine, neurologic or psychiatric

          -  With evidence or history of drug abuse within the past 6 months

          -  Erosive esophagitis, esophageal ulceration, peptic stricture, Barrett's esophagus or
             adenocarcinoma of the esophagus on endoscopy

          -  History of esophagogastric surgery

          -  Gastric or duodenal lesions (ulcer, tumor, etc.)

          -  Women who are pregnant or of childbearing age who are not on contraception

          -  Patients who are unwilling or unable to provide informed consent

          -  Insulin dependent diabetes
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 1
Clinical trial: Memantine Therapy in Amyotrophic Lateral Sclerosis (NCT01020331)

Eligibility criteria:
Inclusion Criteria

          1. Age 18-85

          2. Male or Female

          3. Clinically definite ALS by El Escorial criteria

          4. Elevated levels of Tau in CSF

        Exclusion Criteria:

          1. Patients with FVC below 1.5 L or who require respiratory assistance

          2. History of liver disease

          3. Severe renal failure

          4. History of intolerance to Riluzole or Memantine

          5. Any other co morbid condition which would make completion of trial unlikely

          6. If female, pregnant or breast-feeding; or, if of childbearing age, an unwillingness to
             use birth control.

          7. Taking any trial medications. Non-trial medications are not cause for exclusion.

          8. Unwillingness to provide consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient description (patient's own words): I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Does the patient match the trial criteria? 1