araag2/NLI4PR huggingface dataset:
Clinical trial: Monounsaturated Fatty Acids and Brown/Beige Adipose Tissue in Humans (NCT03024359)

Eligibility criteria:
Gender: Both Age: 25 to 40 years

        Body mass index (BMI):

        Normal body weight group: BMI lower than 25 kg/m2 Obese group: BMI between 30 and 35 kg/m2

        Exclusion Criteria:

          1. Living outside of São Paulo;

          2. pregnant women;

          3. patients with severe or non-stabilized neurological or psychiatric problems;

          4. use of anti-obesity or lipid-lowering medication;

          5. use of adrenergic or benzodiazepine drugs;

          6. individuals with neoplasms, transmissible and rheumatic diseases, hepatic or renal
             insufficiency, untreated thyroid dysfunction; Diabetes mellitus;

          7. individuals that changed more than 5% of body weight in the last six months; 8) to be
             carrying out some kind of diet or modification in the usual dietary pattern; 9) having
             metal prostheses.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 25 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? 0
Clinical trial: Intra-Articular 0.5 % Lidocaine Injection for Osteoarthritis (NCT02632565)

Eligibility criteria:
Inclusion Criteria:

          -  knee pain for more than 25 of the past 30 days, morning stiffness or less than 30
             minutes, crepitation in the knee

          -  pain for more than 25 of the past 30 days and osteophytes on x-ray examination of the
             knees indicating knee OA

        Exclusion Criteria:

          -  the knees with a history of mechanical derangement, fibromyalgia, skin lesions and
             other risk factors of infection, therapy with anticoagulants and trauma/surgery
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? 1
Clinical trial: Anti-osteoporosis Medication Monitoring and Management Service (NCT02194647)

Eligibility criteria:
Inclusion Criteria:

          -  Age >=50 and one of the below

          -  Newly prescribed with AOMs

          -  Recent change of AOMs

          -  Poor adherence to AOMs

          -  Participating physicians feel that the service will benefit the patient in overall
             osteoporosis and medication managements.

        Exclusion Criteria:

          -  Life expectancy less than 2 years or can't be assessed for communication problems

          -  patient in our fracture liaison service or other medication clinical trials
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 1
Clinical trial: Esophagogastric Junction Distensibility During Hiatal Hernia Repair (NCT04450628)

Eligibility criteria:
Inclusion Criteria:

          -  Patient undergoing hiatal hernia repair (types I-IV included) and fundoplication

          -  Absence of spastic esophageal disorders (i.e. jackhammer esophagus, achalasia types
             I-III) or esophageal dysmotility (any evidence of ineffective esophageal motility
             disorder with failed swallows in > 50% of swallows and DCI < 450, or fragmented
             peristalsis as defined by Chicago Classification) assessed by preoperative
             high-resolution manometry

          -  Adult patients ≥18 years

          -  Elective repairs

        Exclusion Criteria:

          -  Redo hiatal hernia repairs

          -  Emergent repairs

          -  Patients with contraindication to surgery or endoscopy

          -  Patients with esophageal varices

          -  Cases with insufficient esophageal length in which fundoplication is unable to be
             performed or a Collis gastroplasty is required

          -  Presence of IEM on Manometry

          -  Connective tissue diseases such as scleroderma or lupus
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 0
Clinical trial: FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women (NCT02674178)

Eligibility criteria:
Inclusion Criteria:

          -  less than 41 years old , with normal menstrual cycle with a range of 24 - 35 days with
             day 3 FSH less than 10 mIU/ml in natural cycle and normal serum prolactin . All women
             had normal uterine cavity determined by previous hysterosalpingography or hysteroscopy

        Exclusion Criteria:

          -  Women with abnormally low Gn as hypothalamic hypogonadism , High LH as PCOS and women
             with abnormal endocrine functions as abnormal thyroid or adrenal functions were
             excluded. Any woman with ovarian cyst or azopermic male partner was also excluded.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients (NCT00004451)

Eligibility criteria:
Inclusion Criteria:

          -  Three groups of subjects are eligible for this study: Healthy young adults between
             ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed
             with Parkinson's disease

        Exclusion Criteria:

          -  Prior surgery to remove part of the stomach

          -  Diabetes, Addison's, or Cushing's diseases
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 0
Clinical trial: Quantitative Assessment of Distal Radioulnar Joint Stability With Pressure-Monitor Ultrasonography (NCT03658096)

Eligibility criteria:
Inclusion Criteria:

          -  healthy volunteers

          -  DRUJ instability patients

        Exclusion Criteria:

          -  the participants who had a history of previous wrist trauma and wrist pain will be
             excluded
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? 0
Clinical trial: Nab-paclitaxel Combined With S-1 Treating Diffuse Type of Stage Ⅲ Gastric Cancer (NCT03977220)

Eligibility criteria:
Inclusion Criteria:

          -  gastric cancer patients after radical resection

          -  diffuse type gastric cancer stage III

        Exclusion Criteria:

          -  Patients who have metastasis disease

          -  Patients who can not tolerate chemotherapy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1
Clinical trial: Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents (NCT02216552)

Eligibility criteria:
Inclusion Criteria:

          -  13 to <18 years of age

          -  BMI considered overweight (BMI > 25 kg/m2 ) or obese (BMI > 30 kg/m2 )

          -  Confirmed 1H-MRS defined hepatic steatosis (>5.5% fat/water)

          -  Parent/Guardian willing and able to provide written, signed informed consent, and
             subjects willing to co-sign parental consent

          -  Sexually active subjects must be willing to use an acceptable method of contraception

          -  Females of child bearing potential must have a negative pregnancy test at screening.

        Exclusion Criteria:

          -  The use of any chronic medications with the exception of oral birth control and
             natural health products with the exception of multivitamins.

          -  Adolescents with altered insulin sensitivity or tissue lipid content unrelated to
             obesity and the metabolic syndrome, including:

        type 2 diabetes; present or previous malignancy renal disease, hypertension (anyone who has
        BPs over the 99th percentile for age and gender) or liver disease;

          -  significant weight loss (10% in last six months) or enrolled in weight loss program in
             the six months prior to the study;

          -  self-reported history of alcohol consumption of greater than two drinks per day and/or
             drinking alcohol more than once weekly;

          -  report using non-prescription recreational drugs;

          -  allergies or sensitivities to any of the ingredients in the investigational product or
             placebo;

          -  females breastfeeding at screening or planning on becoming pregnant at any time during
             the study;
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 13 Years old.
Subject must be at most 18 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? 0
Clinical trial: Comparison of Salivary and Serum Free Testosterone in Normal and Hypogonadal Men (NCT01909505)

Eligibility criteria:
Inclusion Criteria:

          -  Normal male subjects aged 20-65 years

        Exclusion Criteria:

          -  Women Smokers, HIV positive, diabetes, hepatatis C positive, subjects currently taking
             testosterone who are unwilling to suspend use for teh duration of the trial, subjects
             taking aldactone or medicines that may interfere with the protocol
Male
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 0