araag2/NLI4PR huggingface dataset:
Clinical trial: Is the Concentration of Anti-Muellerian Hormon (AMH) Depending on the Menstrual Cycle? (NCT03398603)

Eligibility criteria:
Inclusion Criteria:

          -  Regular natural menstrual cycle between 24 and 32 days

          -  Body Mass Index (BMI) between 19 and 26 kg/m2

          -  Negative serum titer for HIV, Hepatitis B and Hepatitis C

          -  Non-smoker

          -  Willingness to visit the clinic every second day of two non-consecutive menstrual
             cycles.

        Exclusion Criteria:

          -  Intake of hormonal medication like contraceptives

          -  Pregnancy/breast feeding

          -  Known infertility

          -  Known former or actual hormonal disorder

          -  Polycystic ovarial syndrom (PCOS)

          -  Participation on another clinical trial during the last 3 months.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 0
Clinical trial: Chronic Pain After Groin Hernia Repair (NCT02751190)

Eligibility criteria:
Inclusion criteria:

          -  Unilateral, elective, groin hernia repair

        Exclusion criteria:

          -  Bilateral hernia repair

          -  Emergent repair (<24h of duration with signs of incarceration)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 15 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Behavioral Change Communication (BCC) to Promote Physical Activity Among Females With Type 2 Diabetes Mellitus Attending Diabetic Clinic (NCT00690326)

Eligibility criteria:
Inclusion Criteria:

          -  females 30to 65yrs. with type-2 Diabetes Mellitus.

          -  Attending Diabetic clinic at a tertiary level hospital(medical college
             Thiruvananthapuram)

          -  on oral hypoglycemics

        Exclusion Criteria:

          -  only one patient from one family

          -  H/o myocardial infarction

          -  nephropathy

          -  autonomic neuropathy

          -  severe limiting osteo arthritis

          -  pregnancy

          -  Mental incompetence
Female
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? 1
Clinical trial: Mixed Methods Assessment of Exercises for Knee OA (NCT02734342)

Eligibility criteria:
Inclusion Criteria:

        Patients must elicit 3 of the 6 symptoms to be included:

          -  forty five years of age and over.

          -  stiffness for less than thirty minutes;

          -  crepitus;

          -  bony tenderness;

          -  bony enlargement;

          -  no palpable joint warmth.

        Exclusion Criteria:

          -  previous lower limb joint injection within three months;

          -  previous hip or knee joint replacement;

          -  any severe cognitive, cardio- respiratory, musculoskeletal or neurological - diagnosis
             that prevents participants from exercising;

          -  insoles or braces;

          -  ligament instability;

          -  participants with a body mass index (BMI) over 40 will be issued with a choice of
             completing in the study or being managed by the National Health Service weight
             management service;

          -  other minor health related issues will be assessed prior to the commencement of the
             study to ensure safe practice.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.


Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? 1
Clinical trial: Proof of Concept Study of EMBalance Decision Support System to Evaluate Balance Disorders (NCT02704819)

Eligibility criteria:
Inclusion Criteria:

          -  Be capable of understanding the information provided

          -  Absence of dementia/uncontrolled psychiatric disorder

          -  Vertigo or chronic dizziness exacerbated by head movements (<12 months)

          -  Sub-acute presentation of dizziness (up to 3 months) without presenting to emergency
             services

        Exclusion Criteria:

          -  Subjects with learning disability or dementia

          -  Patients with uncontrolled psychiatric disorders

          -  Pregnant and breastfeeding women

          -  Patients' incapable or unwilling to give informed consent.

          -  Patients with acute vestibular disorders (present at Accident and Emergency).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient description (patient's own words): The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Does the patient match the trial criteria? 1
Clinical trial: Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma (NCT02613312)

Eligibility criteria:
Inclusion Criteria:

          -  Subject provides informed consent

          -  Subject is >18 years of age

          -  Subject is deemed competent for making medical decisions

          -  Subject is scheduled to undergo chemotherapy followed by surgery and then IMRT

          -  Subject is a surgical candidate

          -  A negative pregnancy test is required in women of child-bearing potential, as standard
             of care.

        Exclusion Criteria:

        •Subject is <18 years old.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? 1
Clinical trial: Study of Voncento® in Subjects With Von Willebrand Disease (NCT02552576)

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of severe type 1, 2A, or 3 VWD where Von Willebrand Factor: Ristocetin
             Cofactor (VWF:RCo) is <20% at screening

          -  Desmopressin acetate treatment is ineffective, contraindicated, or not available for
             subject (type 3 VWD subjects only).

          -  Evidence of vaccination against hepatitis A and B or presence of antibodies against
             hepatitis A and B due to either a previous infection or prior immunization.

          -  Written informed consent given.

          -  Require a VWF product to control a non-surgical bleeding (NSB) event or for ongoing
             prophylactic therapy.

        Exclusion Criteria:

          -  Known history or suspicion of having VWF or FVIII inhibitors

          -  Acute or chronic medical condition, other than VWD, which may affect the conduct of
             the study

          -  Known or suspected hypersensitivity or previous evidence of severe side effects to
             Voncento, VWF / FVIII concentrates, or human albumin.

          -  Participated in another interventional clinical study within 30 days before the first
             administration of Voncento or at any time during the study.

          -  Females who are pregnant, breast-feeding or who have a positive pregnancy test at
             screening

          -  Alcohol, drug, or medication abuse within 1 year before the study.

          -  Currently receiving a therapy not permitted during the study.

          -  Previous participation in a Voncento / Biostate study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient description (patient's own words): I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Does the patient match the trial criteria? 1
Clinical trial: Gut Hormone, Nociceptors, Neurotrophic Factors Expression in Functional Dyspepsia (NCT02173925)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects who completed upper GI endoscopy and questionnaire about gastrointestinal
             symptoms

        Exclusion Criteria:

          -  Daily user of NSAID or anticoagulants

          -  with concomitant systemic diseases such as diabetes mellitus or any malignancy

          -  Participants with major depression, psychosis, eating disorder

          -  Participants with typical reflux symptom

          -  Patients with Benign gastric ulcer or duodenal ulcer

          -  Patients with past gastrointestinal surgery
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 0
Clinical trial: The Primary Symptoms of GERD(Gastroesophageal Reflux Disease) in Chinese Outpatients in Gastroenterology Department (NCT02506634)

Eligibility criteria:
Inclusion Criteria:

          -  Consecutive patients aged 18-65 years who go to the gastroenterology clinic presented
             with upper gastrointestinal discomfort, such as heartburn, regurgitation, dysphagia,
             substernal pain, epigastric pain, epigastric burning, early satiety, postprandial
             fullness.

          -  Whose previous symptoms should last for at least 3 months and be at least 3 days per
             week in frequency with moderate severity.

          -  Able to fill in the questionaires.

        Exclusion Criteria:

          -  gastric or duodenal ulcers, upper GI neoplasms on upper endoscopy

          -  severe cardiac or pulmonary diseases, diabetes or rheumatic diseases

          -  history of operations in the upper GI tract

          -  renal failure or abnormal liver function

          -  use of non-steroidal anti-inflammatory drugs (NSAIDs)

          -  allergy to esomeprazole

          -  Pregnancy or lactating mother
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 1
Clinical trial: Study of Safety And Efficacy Of ReFacto AF In Previously Untreated Hemophilia A Patients In The Usual Care Setting (NCT00950170)

Eligibility criteria:
Inclusion Criteria:

          -  Male subjects <6 years of age with severe hemophilia A (FVIII:C <1%) based on clinical
             records, including newborns.

          -  No prior exposure to factor products or any blood products.

        Exclusion Criteria:

          -  Presence of any bleeding disorder in addition to hemophilia A.

          -  Treatment with any investigational agent or device within the past 30 days.

          -  Any condition(s) that compromises the ability to collect study-related observations,
             or that poses a contraindication to study participation (these conditions include, but
             are not limited to, inadequate medical history to assure study eligibility; and
             expectation of poor adherence to study requirements).
Male
No healthy subjects accepted to join the trial.

Subject must be at most 6 Years

Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0