araag2/NLI4PR huggingface dataset:
Clinical trial: Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis (NCT00136110)

Eligibility criteria:
Inclusion Criteria:

          -  Definite, probable, or probable-laboratory supported ALS according to the revised El
             Escorial World Federation of Neurology criteria.

          -  Intake of riluzole 50 mg twice a day (bid)

          -  A disease duration at inclusion of more than 6 months and less than 36 months
             [inclusive] (disease onset is defined as the date of first symptoms excluding muscle
             cramps and fasciculations)

          -  Vital capacity (VC%) ≥ 70% of normal value (slow expiration, best of a minimum of
             three and a maximum of five measurements, with a respiratory function validly
             assessable and a spontaneous, non-assisted ventilation)

          -  Ages 18 - 85 years (inclusive)

          -  Capable of thoroughly understanding the trial information given; has signed the
             informed consent.

        Exclusion Criteria:

          -  Tracheostomy, tracheostomal ventilation of any type, non-invasive ventilation more
             than 16 hours/ day, or supplemental oxygen during the last three months prior to
             inclusion.

          -  Any medical condition or intoxication known to have an association with motor neuron
             dysfunction, which might confound or obscure the diagnosis of ALS.

          -  Presence of any concomitant life-threatening disease or any disease or impairment
             likely to interfere with functional assessment.

          -  Confirmed hepatic insufficiency or abnormal liver function (ASAT, ALAT greater than
             twice the upper limit of normal range).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient description (patient's own words): I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Does the patient match the trial criteria? 1
Clinical trial: Early Luteal Hormones and IVF Outcomes After hCG Triggering (NCT04693624)

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 - 38

          -  BMI < 28kg/m2

          -  Having 4 to 19 follicles with diameter of 12mm or above on the day of hCG triggering

          -  Receiving a standard GnRH-antagonist protocol for ovarian stimulation

          -  Having indication for fresh embryo transfer

          -  Willingness to participate in the study, and to disclose any medical conditions to the
             investigator. The patient must be prepared and willing to comply with the requirements
             of the protocol.

          -  The patient should after appropriate oral and written consent understand the study and
             be informed that she may withdraw consent at any time without prejudice to future
             medical care.

        Exclusion Criteria:

          -  Previous poor ovarian response (≤ 3 follicles) after appropriate FSH stimulation

          -  Hyper-response defined as >20 follicles ≥ 14 mm on the day of trigger

          -  Chronical medical conditions like Diabetes, Crohns disease, Thyroid disease, Hepatitis
             B, Sexually Transmitted Diseases and simultaneous participation in an interventional
             clinical trial.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 38 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Ovulation and Follicular Development Associated With Mid Follicular Phase Initiation of Combined Hormonal Contraception (NCT03077555)

Eligibility criteria:
Inclusion Criteria:

          -  healthy women, age 18 - 40 years

          -  prior normal and regular interval of menstruation

        Exclusion Criteria:

          -  current breast feeding women

          -  within 1 month period of child-delivery or miscarriage

          -  body mass index 30 kg/m2 or more

          -  contraindicated to use combined hormonal contraception

          -  current using other hormonal drugs that affect ovulation function
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledgeted Sutures vs. Sutures Only (NCT04591860)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with a large hiatal hernia - admitted for surgery (laparoscopic /
             robot-assisted)

          -  Written informed consent

          -  ≥ 18 years of age

          -  Hiatal hernia documented by barium x-ray and/or gastroscopy and/or manometry by one or
             more of the following criteria:

               -  > 5cm hiatal hernia

               -  1/3 of the stomach in the thorax

        Exclusion Criteria:

          -  Lack of patient consent for study participation

          -  Lack of consent to study due to linguistic or mental incomprehension

          -  Patients in poor general condition (lack of anesthesia ability)

          -  Pregnancy

          -  Prior surgery on the stomach or gastroesophageal junction

          -  Simultaneous surgery because of another illness
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 1
Clinical trial: The Efficacy of TGF for Treating Osteoarthritis of the Knee (NCT03562429)

Eligibility criteria:
Inclusion Criteria:

          1. age between 50~75 years old

          2. diagnosis of osteoarthritis: The Clinical/Radiographic classification criteria of
             American College of Rheumatology, ACR

          3. chronic knee pain over 3 months.

        Exclusion Criteria:

          1. the past history with systemic joint disease, such as autoimmune disease

          2. the patient with history of knee surgery or waiting for the total knee replacement

          3. any disease that affect the function of lower extremities, such as trauma, tumor or
             compensation of abnormal posture

          4. the condition that cannot participate this study

          5. the subjects non-compliance with the protocol
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 75 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? 1
Clinical trial: A Study to Confirm the Accuracy of Locally Advanced Gastric Cancer Diagnosis (NCT04440605)

Eligibility criteria:
Inclusion Criteria:

          -  Histological prove of adenocarcinoma of the stomach by endoscopy

          -  Preoperative imaging data by contrast-enhanced CT and clinical TNM stages were given

          -  No evidence of stage IV disease

          -  No previous gastrectomy or preoperative treatment.

        Exclusion Criteria:

          -  Discovery of distant metastasis (stage IV) during surgery

          -  Number of retrieved lymph node less than 15
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome. (NCT04111341)

Eligibility criteria:
Inclusion Criteria:

          -  Age ≥20 years old

          -  Written informed consent obtained

          -  Been diagnosed with the diagnostic criteria for Sjogren's syndrome (according to the
             2002 European Classification Standard)

          -  The ESSPRI score of the patient of Sjogren's syndrome at least> 3

        Exclusion Criteria:

          -  Have association disease about heart, lung, nerve or mental

          -  Pregnant or breastfeeding women

          -  Laboratory abnormality:

               1. Serum creatinine ≥2.0 mg/dl

               2. Male: Hb≤9 g/dl;Female: Hb≤8.5 g/dl

               3. Neutrophil or lymphocyte<0.5 x 109/l
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Oral T7 Oral Testosterone in Man (NCT00842751)

Eligibility criteria:
Inclusion Criteria:

          -  Males between 18 and 50 years of age

          -  In good health based on normal screening evaluation (consisting of a medical history,
             physical exam normal serum chemistry, hematology, and baseline hormone levels.

          -  Must agree to not participate in another research drug study

          -  Must agree to not donate blood

          -  Must be willing to comply with the study protocol and procedures

        Exclusion Criteria:

          -  Men in poor general health, with abnormal blood results (clinical laboratory tests or
             hormone values)

          -  A known history of alcohol or drug abuse

          -  Participation in a long-term male contraceptive study within the past month

          -  History of bleeding disorders or current use of anti-coagulants

          -  History of sleep apnea

          -  History of major psychiatric disorder

          -  Body mass index > 37

          -  Infertility

          -  Hematocrit > 55 or < 30

          -  PSA >4
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 0
Clinical trial: Study Of Axitinib In Combination With Cisplatin And Capecitabine In Patients With Advanced Gastric Cancer (NCT00842244)

Eligibility criteria:
Inclusion Criteria:

          -  confirmed diagnosis of stomach cancer

          -  advanced stomach cancer of stage IV

          -  adequate blood chemistry, blood counts and kidney function

          -  willing to participate to study requirements and sign an informed consent document

        Exclusion Criteria:

          -  prior chemotherapy for stomach cancer in its advanced stage

          -  excessive toxicities related to prior therapies

          -  pregnant or breastfeeding patients
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 1
Clinical trial: Screening Questionnaire for Respiratory Muscle Weakness and Sleep-disordered Breathing in Neuromuscular Disorders (NCT02833168)

Eligibility criteria:
Inclusion Criteria:

          -  proven neuromuscular disease known to be potentially associated with diaphragmatic
             weakness (group 1)

          -  newly diagnosed obstructive sleep apnea with an apnea hypopnea index > 15/h total
             sleep time (group 2)

          -  newly diagnosed narcolepsy, hypersomnia, insomnia or parasomnia in the absence of any
             sleep-related breathing disorder (group 3)

          -  availability of recent diagnostic sleep studies including polysomnography and
             transcutaneous capnography

        Exclusion Criteria:

          -  ongoing CPAP oder non-invasive ventilation

          -  inability to participate in study procedures

          -  severe lung disease
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient description (patient's own words): I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Does the patient match the trial criteria? 1