araag2/NLI4PR huggingface dataset:
Clinical trial: Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions. (NCT01409551)

Eligibility criteria:
Inclusion Criteria:

          -  Recurrent symptomatic malignant pleural effusion

          -  No prior intrapleural therapy

          -  Abscence of bronchial obstruction or fibrosis preventing lung reexpansion

          -  No systemic chemotherapy immediately prior to or during the first 30-day interval
             following pleurodesis

        Exclusion Criteria:

          -  Poor Karnofsky Performance Status
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.

Subject must be at most 75 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? 1
Clinical trial: Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment (NCT01529242)

Eligibility criteria:
Inclusion Criteria:

          -  Consent of the patient or legal guardian;

          -  Clinical diagnosis of acute cutaneous rash defined by the presence of erythematous
             papules on healthy skin, different sizes, itchy and fleeting

          -  Children aged between 2 and 11 years and 11 months (up to 30 kg);

        Exclusion Criteria:

          -  Participation in clinical trial in 30 days prior to study entry;

          -  Patients with history of hypersensitivity to desloratadine or prednisolone or with
             corticosteroids use contraindications ;

          -  Patients with any clinically significant disease other than cutaneous rash including
             hematopoietic, cardiovascular, renal, neurological, psychiatric or autoimmune
             disorders;

          -  Patients on treatment with monoamine oxidase inhibitors (MAOIs);

          -  Patients diagnosed with other dermatoses
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 11 Years

Patient description (medical language): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient description (patient's own words): I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Does the patient match the trial criteria? 0
Clinical trial: Treatment of Severe Male Infertility - Predictive Factors (Imaging) (NCT02931721)

Eligibility criteria:
Inclusion Criteria:

          -  non obstructive azospermia

        Exclusion Criteria:

          -  malignancy

          -  contraindication for fertility treatment
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? 0
Clinical trial: Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome (NCT02774707)

Eligibility criteria:
Inclusion criteria

          -  Healthy volunteer control without ophthalmic history

          -  Patients with Primary Sjogren's syndrome: according to the classification of American
             European Consensus Group of rheumatologist and Ophthalmologists,

          -  Patient with Secondary Sjogren's syndrome: Sjogren's syndrome associated with systemic
             lupus erythematosus, systemic sclerosis (scleroderma), rheumatoid arthritis, mixed
             connective tissue disease, inflammatory muscle disease, autoimmune liver disease, and
             autoimmune thyroid disease

          -  Ocular graft versus host disease

          -  Volunteers with dry eye symptoms but not diagnosed with primary Sjogren's syndrome,
             secondary Sjogren's syndrome and ocular graft versus host disease

        Exclusion criteria

          -  Patients who decline to receive the venipuncture for blood sampling.

          -  Patients younger than 20 years old or older than 80 years old.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Loop Band Validation Study (NCT03240926)

Eligibility criteria:
Inclusion Criteria:

          -  Patient has capacity to consent for the study.

          -  Anesthetic plan for an arterial line for vital sign monitoring during their surgical
             procedure.

        Exclusion Criteria:

          -  Active Atrial Fibrillation

          -  Active C-difficile

          -  Amputation of the arm at the wrist or above

          -  The Investigator and/or Clinical Research Nurse will conduct a visual inspection for
             attributes that may diminish device accuracy. These include but are not limited to:
             tattoos over the radial artery, burns or heavy scarring over the radial artery,
             fragile skin, any skin diseases affecting the wrist or arm, Physician discretion-any
             condition deemed inappropriate that will preclude use of the device.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? 0
Clinical trial: The Validity of Bone Age Assessment by an Ultrasound Apparatus (SonicBone) (NCT01346618)

Eligibility criteria:
Inclusion Criteria:

          -  Children aged 4-17 years old

          -  Children who performed or will perform a hand x-ray as part of their clinical work up
             within 2 months from study enrolment

          -  A signed Informed Consent Form that was obtained from at least one parent or legal
             guardian and an audio approval by the other (phone call), if available, prior to
             ultrasound study.

          -  An assent from the child to perform the SonicBone's BA device reading

        Exclusion Criteria:

          -  Children taking any medication that might change bone metabolism or mineralization
             within the last year (glucocorticosteroids, sex steroids, oral contraceptives,
             anticonvulsants, calcium and vitamin D in superphysiological doses)

          -  Children with suspected bone diseases or multiple fractures.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 4 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? 1
Clinical trial: Metabolic Effects of Androgenicity in Aging Men and Women (NCT00680797)

Eligibility criteria:
Inclusion Criteria:

          -  males age 60-85 years

          -  non-diabetic fasting glucose and 2-hour oral glucose tolerance test (OGTT)

          -  overall good general medical health and signed informed consent

          -  willing to travel to West Los Angeles VA and University of California, Los Angeles in
             Los Angeles, California

        Exclusion Criteria:

          -  any clinically significant abnormalities detected on screening physical exam or
             laboratory testing (e.g. prostate specific antigen > 4)

          -  or other symptom or history of a significant underlying medical or psychiatric illness

          -  BMI < 20 or > 40

          -  subjects already on testosterone therapy or medications that might influence glucose
             regulation or hormone levels

          -  subjects with a history of deep venous thromboses, pulmonary embolism, breast cancer,
             prostate cancer, polycythemia or other contraindications to estrogen or testosterone
Male
Accepts Healthy Volunteers
Subject must be at least 60 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 0
Clinical trial: Risk Factors for Ectopic Pregnancy: Comparison of Fresh and Warmed Transfers. Analysis of a 10 Years, a Single Center Experience. (NCT04325854)

Eligibility criteria:
Inclusion Criteria:

          -  Women with diagnosis of EP. Ectopic pregnancy diagnosis was performed with B-hcg
             measurement and imaging visualization of the gestational sac outside the uterus

        Exclusion Criteria:

          -  No case was excluded
Female




Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 1
Clinical trial: Does the Volume of the Embryo Culture Medium During Embryo Transfer Affects the IVF Outcomes? (NCT03350646)

Eligibility criteria:
Inclusion Criteria:

          1. Age ≤ 45y.o.

          2. BMI≤36 kg/m2,

          3. Baseline FSH concentration <15 IU/l,

          4. Ovarian stimulation with the same GnRH antagonist protocol

          5. Normal uterine cavity with endometrium thickness >7mm and trilaminar morphology at the
             Time of transfer and semen

          6. Parameters of >1 million /ml motile spermatozoa with >4% physiological morphology -

        Exclusion Criteria:

          1. PGD cycles

          2. Frozen -thaw cycles

          3. Natural cycles or patients following different ovarian stimulation protocol were
             excluded from the study

             -
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Activity and Content of Factor VIII (FVIII) in Human Plasma: The Assessment of a Novel Immunoassay (NCT00839202)

Eligibility criteria:
Inclusion Criteria:

          -  adults with hemophilia A

          -  factor VIII less that 2%

          -  informed consent signed

          -  absence of an inhibitor

        Exclusion Criteria:

          -  history of a high responding inhibitor anemia
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0