Clinical trial: Jinhua Qinggan Granules in the Treatment of COVID-19 (NCT04723524)

Eligibility criteria:
Inclusion Criteria:

          -  1) Between the ages of 18-75 years, both male and female.

          -  2) Confirmed Coronavirus infection by real time RT-PCR.

          -  3) Mild cases of Coronavirus having main symptoms with minimum 2 grade (as mentioned
             in 7.1.6).

          -  4) The subject has signed the informed consent form;

        Exclusion Criteria:

          -  1) Younger than 18 years or older than 75 years.

          -  2) Patients with moderate or critical Coronavirus infection confirmed by real time
             RT-PCR; cases meeting any of the following criteria:

               1. Lung lesions

               2. Respiratory failure and requiring mechanical ventilation

               3. Shock

               4. With other organ failure that requires ICU cares.

          -  3) Severe primary health conditions associated with cardiovascular, cerebrovascular,
             pulmonary, hepatic, renal, endocrine and hematological diseases, hematopoietic system
             (above grade II of cardiac function; ALT & AST are 1.5 times higher than the normal
             value; Creatinine above the upper limit of normal value) and mental illness or serious
             diseases affecting their survival, such as cancer or AIDS;

          -  4) With severe cardiopulmonary dysfunction, cardiopulmonary insufficiency.

          -  5) Subjects, who took other antiviral, antibacterial, cough relieving, expectorant and
             antiasthmatic drugs within 3 days prior to the visit (including β2 receptor agonists,
             anticholinergic agents, theophylline drugs, glucocorticoids, expectorant and Chinese
             Medicine.)

          -  6) Allergic individuals and those who are known to be allergic to experimental drugs

          -  7) Pregnant women, lactating women or fertile women who are ready to conceive in 3
             months.

          -  8) Subject, who has participated in the past 1 month in another clinical study.

          -  9) Subjects who are not suitable for the clinical trial based on investigators'
             judgment.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 1