araag2/NLI4PR huggingface dataset:
Clinical trial: STRETTA ,Radio Frequency Ablation (RFA) v/s Sham Therapy for the Treatment of Refractory GERD (NCT02935881)

Eligibility criteria:
Inclusion Criteria:

          -  Age > 18years

          -  Small hiatus hernia (< 2-3 cm)

          -  Los Angeles Grade 'A' or 'B' Reflux Esophagitis

          -  LES pressure : 5 - 15 mm Hg

          -  PPI dependent / refractory GERD

          -  24 hr acid exposure study showing abnormal esophageal acid exposure > 4%

          -  DeMeester Score >14.7

          -  Esophageal manometry showing normal peristalsis

        Exclusion Criteria

          -  Age < 18 years

          -  Large hiatus hernia (> 3 cm)

          -  Los Angeles Grade 'C' or 'D' Reflux Esophagitis

          -  LES pressure : < 5 or > 15 mm Hg

          -  Underlying coagulation disorder

          -  Previous Esophageal or Gastric surgery

          -  H/o coronary artery disease (CAD)

          -  Esophageal manometry showing ineffective peristalsis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? 0
Clinical trial: Menstrual Cycle Symptom Tracking (NCT04756739)

Eligibility criteria:
Inclusion Criteria:

          -  Female

          -  Aged 18 years and over

          -  Regular menstrual cycles

          -  Owns a compatible smart phone i.e. iPhones® and AndroidTM phones equipped with
             Bluetooth® 4.0/BLE

          -  Willing to use their own smartphone for the duration of this study and to download and
             install the study app

          -  Willing to give informed consent

        Exclusion Criteria:

          -  Currently trying to conceive

          -  Currently or recently pregnant or breastfeeding

          -  Taking any treatment which may affect the menstrual cycle (e.g. contraceptive pill,
             fertility medications or hormone replacement therapy)

          -  Taking or undergoing any other medical treatment for fertility such as ovulation
             drugs, artificial insemination and assisted fertility such as In vitro fertilization
             (IVF) or Intracytoplasmic sperm injection (ICSI)

          -  Has abnormal liver or kidney function

          -  Taking antibiotics containing tetracycline

          -  Taking clomiphene citrate or other ovulation induction drugs
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 1
Clinical trial: Vital Sign Comparison Between Lifelight and Standard of Care - Development (NCT04003662)

Eligibility criteria:
Inclusion Criteria:

          -  I1. Sufficiently conversant in the English language to satisfy I3.

          -  I2. Able and willing to comply with all study requirements.

          -  I3. Able and willing to provide written informed consent to participate (including by
             parent or legal guardian if under 16 years old).

        Exclusion Criteria:

          -  There are no exclusion criteria.
No condition on gender to be admitted to the trial.

Subject must be at least 3 Years old.


Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: fMRI of Vulnerable Brain Regions in Persons at Risk for Alzheimer's Disease (NCT00478491)

Eligibility criteria:
Inclusion Criteria:

          -  MCI Group: Diagnosis of mild cognitive impairment

          -  AD Family History Group: Confirmed family history of Alzheimer's and concurrent
             enrollment in the Wisconsin Registry for Alzheimer's Prevention (WRAP)

          -  Control Groups: Cognitively healthy and both parents survived past age 70 with no
             memory problems

        Exclusion Criteria:

          -  Claustrophobia

          -  Metallic or electronic implants or devices that are not MRI-safe
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? 1
Clinical trial: Low Dose Ionizing Radiation Using CT Scans as a Potential Therapy for Alzheimer's Dementia: A Pilot Study (NCT03597360)

Eligibility criteria:
Inclusion Criteria:

          1. Males or females with severe AD dementia (MMSE<12) between the ages of 70 to 90 years.

          2. Meet the criteria of AD (NIA-AA).

          3. If on any of the following medications: acetylcholinesterase inhibitors and/or
             memantine, participants must be on a stable dose for at least 60 days.

          4. Clinically stable for at least 3 months.

        Exclusion Criteria:

          1. Current or past history of malignancy.

          2. Previous history of radiotherapy.

          3. Neurological disorder other than AD.

          4. Currently receiving other experimental treatments.

          5. Clinical or imaging evidence of stroke (with more than 1-2 lacunar infarcts on CT scan
             or MRI).

          6. Major depression, bipolar affective disorder or psychosis.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 70 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient description (patient's own words): I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Does the patient match the trial criteria? 1
Clinical trial: Laparoscopic Recurrent Inguinal Hernia Repair (NCT04266561)

Eligibility criteria:
Inclusion Criteria:

          -  Recurrent inguinal hernia

        Exclusion Criteria:

          -  complicated inguinal hernia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 4 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 0
Clinical trial: A Clinical Trial to Study the Safety and Efficacy of Chandrakanthi Choornam in Patients With Low Sperm Count (NCT02234206)

Eligibility criteria:
Inclusion criteria:

          -  Male infertile Patients with age between 21-45 yrs

          -  Marriage history for >1 year

          -  Abnormal Sperm count 1-15 million/ml

          -  Patients with normal Liver & Renal function test

          -  Willing to give specimen of semen before & at the end of the clinical trial

          -  Informed patients giving written consent

        Exclusion criteria:

          -  Azoospermia - complete absence of sperm cells in the ejaculate

          -  Aspermia - complete lack of semen

          -  Necrospermia- Spermatozoa in semen are either immobile or dead.

          -  Clinical diagnosis of Varicocele & Hydrocele

          -  History of Undescended testis

          -  Inguinal hernia on physical examination

          -  Male accessory gland infection

          -  History of DM, Hypertension and Cardiac disease

          -  Any recent medical or surgical illness

          -  Underwent treatment for promoting Spermatogenic fertility in last 3 months

          -  Other Systemic disease requiring specific therapies

          -  Known Thyroid disease

          -  Past history of Renal, Hepatic or any other chronic illness in the Patient
Male
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? 0
Clinical trial: Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone (NCT00161421)

Eligibility criteria:
Inclusion Criteria:

          -  Male 18-50 yrs old

          -  In good general health based on normal screening evaluation (consisting of medical
             history, physical exam, normal serum chemistry, hematology, and baseline hormone
             levels)

        Exclusion Criteria:

          -  Poor general health, with abnormal blood results at screening

          -  A known history of alcohol or drug abuse

          -  Participation in a long-term male contraceptive study within three months of screening
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? 1
Clinical trial: Movement Enhancing Device for Children (NCT01959581)

Eligibility criteria:
Inclusion Criteria:

        • Infants will be invited to participate if they are between 1 month and 6 years and:

          -  Were born < 36 weeks of gestational age with periventricular leukomalacia or grade III
             or IV intraventricular hemorrhage

          -  Were born > 36 weeks of gestational age with encephalopathy related to perinatal
             asphyxia

          -  Have the diagnosis of neonatal stroke or intracranial hemorrhage

          -  Have brachial plexus palsy

          -  Have arthrogryposis multiplex congenital

          -  Have Down syndrome

          -  Have congenital hypotonia

        Exclusion Criteria:

        • blindness or severe sensory motor impairments that would prohibit the child from
        completing the study assessment.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 1 Month old.
Subject must be at most 6 Years

Patient description (medical language): A 15-week-old infant brought to the clinic for the follow up. The infant has flat facies, small ears, a single palmar crease, and upward slanting eyes. He was born on 39th week to a 39-year-old woman who didn't have prenatal care. The medical record confirms the trisomy of chromosome 21 (Down syndrome). The infant is otherwise healthy.

Patient description (patient's own words): My newborn, who is only 15 weeks old, had one of his follow-up appointments. The doctor pointed out that my baby had a flat face, small ears, only one palm line, and small eyes. He was born on his 39th week, while I was 39. What a coincidence! To be honest, I did not go to the doctor during my pregnancy. The doctor diagnosed my baby with Down syndrome. Apart from that he's healthy.

Does the patient match the trial criteria? 1
Clinical trial: Comparison of the Effect of Propacetamol, Ibuprofen or Their Combination on Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children (NCT03352362)

Eligibility criteria:
Inclusion Criteria:

          -  scheduled to undergo laparoscopic inguinal hernia surgery

          -  American Society of Anesthesiologists physical status classification 1 or 2

          -  Children aged 6 months to 6 years

        Exclusion Criteria:

          -  history of Gastrointestinal bleeding

          -  history or laboratory finding of suspected renal or hepatic dysfunction

          -  bronchial asthma

          -  bleeding disorder

          -  hypersensitivity to NSAID or propacetamol

          -  disagreement of investigation

          -  The researcher determines that participation is inappropriate due to other reasons.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 6 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 0