araag2/NLI4PR huggingface dataset:
Clinical trial: Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding (NCT04461639)

Eligibility criteria:
Inclusion Criteria:

          -  Signed informed consent/assent will be obtained before any study-related activities

          -  PTPs with hemophilia A assigned to Jivi prophylaxis treatment

          -  Negative FVIII inhibitor test before study entry

          -  Decision to initiate treatment with commercially available Jivi has been made by the
             treating physician before and independently from the decision to include the patient
             in this study

        Exclusion Criteria:

          -  Known or suspected contraindications to Jivi or related products

          -  Mental incapacity, unwillingness or other barriers precluding adequate understanding
             or cooperation

          -  Participation in an investigational program with interventions outside of routine
             clinical practice
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.


Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 1
Clinical trial: Effects of Growth Hormone (GH) Treatment on Eating Regulation (NCT00562705)

Eligibility criteria:
Inclusion Criteria:

          1. Height of at least 2.0 standard deviations below the mean height for chronological age
             and sex according to the 2000 standards from the Centers for Disease Control and
             Prevention (CDC).

          2. Children that have one of the following short stature pathologies:

               1. IGHD or MPHD

               2. ISS

               3. SGA

          3. Proper function of thyroid gland, kidney and liver

          4. Prior to initiating growth hormone treatment

        Exclusion Criteria:

          1. Chronic diseases

          2. Diseases in the digestive system.

          3. Neurological diseases.

          4. Malignant diseases in the past or in the present. Treated with chemotherapy or
             radiation.

          5. Genetic syndromes

          6. Bone diseases

          7. Taking chronic medicine, SSRI type, that effect the appetite and the growth hormone
             signal transduction.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 18 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? 0
Clinical trial: Palatability (Energy I Pilot) (NCT01653886)

Eligibility criteria:
Inclusion Criteria:

          -  You are between the ages of 18 and 50, inclusive, if you are a male or between the
             ages of 18 and 45, inclusive, if you are a female.

          -  your body mass index (BMI) is between 25 and 30 kg/m2, inclusive

          -  For females, if you have regular menstrual periods, with no less than 28 day cycles.

        Exclusion Criteria:

          -  you have a chronic disease that affects body weight, appetite, or metabolism, such as
             diabetes and cardiovascular disease.

          -  You use prescriptions or over-the-counter medications or herbal products that affect
             metabolism or body weight (e.g. weight loss medications such as sibutramine, or
             orlistat).

          -  You have symptoms of depression or excessive dietary restraint.

          -  You have an allergy to one or more of the test foods.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 0
Clinical trial: A Study Using Imaging Technology to Measure Changes in Bone Structure After Treatment With Teriparatide (NCT00557310)

Eligibility criteria:
Inclusion Criteria:

          -  postmenopausal (after the "change of life") women with osteoporosis

          -  between the ages of 45-85

          -  have low bone mass as determined by a bone density test

          -  have at least one prior atraumatic vertebral or nonvertebral fracture(with a T-score
             of -2.0 or lower at the lumbar spine, total hip, or femoral neck) or, no prior
             fracture (with a T-score of -3.0 or lower at these same sites)

          -  could have taken up to 5 years total of certain oral osteoporosis medications such as
             alendronate, risedronate, or ibandronate

        Exclusion Criteria:

          -  have conditions that would affect the bone in the region of the wrist or have had a
             previous fracture of either wrist which might affect results of study

          -  have a metal implant or have had a hip replacement in either hip which might affect
             results of study

          -  have an increased risk of osteosarcoma; includes Paget's disease of bone, a previous
             bone tumor, or x-ray treatment to the skeleton

          -  currently have active or suspected diseases that affect the bone, other than
             osteoporosis

          -  have abnormal levels of calcium, parathyroid hormone in blood, or other laboratory
             values
Female
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 1
Clinical trial: Dental and Periodontal Status of Patients With Sjögren's Syndrome. (NCT04848870)

Eligibility criteria:
Inclusion Criteria:

          -  Patient with Sjögren Syndrome

          -  Patient > 18 years old

          -  Patient affiliated to a social security system, beneficiary or beneficiary of a right
             other than AME

          -  Patient who speaks and understands French well enough to be able to read and
             understand the study information note.

          -  Patient who does not object to his participation in the study

        Exclusion Criteria:

        - Patient having expressed his opposition to participate in the research
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Quality of Life After Laparoscopic Inguinal- Incisional and Umbilical Herniotomy. (NCT01289093)

Eligibility criteria:
Inclusion Criteria:

          -  elective laparoscopic and open operations for inguinal hernia

          -  elective laparoscopic operation for incisional- and umbilical hernia

          -  primary hernia

          -  uni-bilateral hernias and one or more incisional hernias

        Exclusion Criteria:

          -  expected bad compliance to the study

          -  acute operations

          -  re-operations

          -  secondary operations

          -  primary operation with reoperation within 30 days
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient description (patient's own words): I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Does the patient match the trial criteria? 1
Clinical trial: Treatment of Hemophilia A Patients With FVIII Inhibitors (NCT04023019)

Eligibility criteria:
Inclusion Criteria:

          -  Male persons with haemophilia A, of any severity, who have a historical inhibitor
             titer ≥ 0.6 BU/mL, including those who have failed previous immune tolerance induction
             (ITI) attempt(s)

          -  Persons undergoing ITI with Nuwiq, octanate, or wilate and/or receiving prophylactic
             therapy with emicizumab, activated prothrombin complex concentrate (aPCC), or
             activated recombinant factor VII (rFVIIa)

          -  Participants or participants' parent(s)/legal guardian(s) must be capable of giving
             signed informed consent and be able to understand the study documents

        Exclusion Criteria:

          -  Participants are excluded from the study if any coagulation disorder other than
             haemophilia A is diagnosed

          -  Partly retrospective patients will be excluded if detailed documentation on treatment,
             all bleeding episodes, inhibitor titers, and FVIII levels is not available for the
             retrospective period
Male
No healthy subjects accepted to join the trial.



Patient description (medical language): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient description (patient's own words): I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Does the patient match the trial criteria? 0
Clinical trial: Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic (NCT04548934)

Eligibility criteria:
Inclusion Criteria:

          -  Member of the rescue organization "Croce Bianca"

          -  Aged 18-60

          -  Certified in basic life support (BLS)

          -  No current COVID-19 symptoms, not being tested positive for COVID-19, no COVID-19
             symptoms in the 4 weeks before the tests, no quarantine or unprotected contacts with
             COVID positive patients in the last 4 weeks, body temperature ≤ 37.5°on test days.

          -  Obtained informed consent.

        Exclusion Criteria:

          -  Age <16 or >60 years,

          -  No informed consent

          -  Current COVID-19 symptoms, being tested positive for COVID 19 or symptoms in the 4
             weeks before the tests, quarantine or unprotected contacts with COVID-19 positive
             patients in the last 4 weeks, body temperature ≥ 37.5°on test days.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 0
Clinical trial: Predictors of Success of IUI in Unexplained Infertility (NCT02787811)

Eligibility criteria:
Inclusion Criteria:

          -  These patients had at least 1 tube patent

          -  there were no significant intrauterine or pelvic abnormalities demonstrated on
             pelvic-abdominal ultrasonography, hysteroscopy, and/or laparoscopy

          -  serum follicular stimulating hormone (FSH) level of12 mIU/mL or less

        Exclusion Criteria:

          -  A woman's age of more than 40 years,

          -  ovarian cyst detected in the ultrasound examination

          -  uterine lesions such as submucosal leiomyoma, and a previous diagnosis of moderate to
             severe pelvic endometriosis.

          -  women with body mass index > 35 kg/m2,

          -  PCOS/anovulatory patients

          -  signs of hyperandrogenemia
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Percutaneous Vertebroplasty: Prophylactic Treatment of Adjacent Vertebra (NCT00635297)

Eligibility criteria:
Inclusion Criteria:

          -  CT and MRI proven non healed painful osteoporotic compression fracture in the thoracic
             and lumbar spine.

        Exclusion Criteria:

          -  Infection

          -  High grade spinal stenosis

          -  Contraindications to MRI

          -  Dementia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman

Does the patient match the trial criteria? 1
Clinical trial: China Obstetrics and Gynecology Journal Club (NCT01844609)

Eligibility criteria:
Inclusion Criteria:

          -  Chinese medical professional

        Exclusion Criteria:

          -  English speaking fluency

          -  Non-Chinese speaking medical professional
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? 1