araag2/NLI4PR huggingface dataset:
Clinical trial: Effect of Transcutaneous Electrostimulation (TENS) on Pain and Physical Function in Patients With Knee Osteoarthritis (NCT01875042)

Eligibility criteria:
Inclusion Criteria:

          -  Men and women of at least 18 years of age

          -  Clinical or radiological diagnosis of knee OA according to the criteria of the
             American College of Rheumatology

          -  Knee pain lasting for six months or longer

          -  Radiographic evidence of at least one osteophyte at the tibiofemoral joint
             (Kellgren-Lawrence grade ≥ 2) or one or more of the following signs and symptoms in
             the knee; restricted range of motion, pain in motion, crepitations, morning stiffness

          -  Written informed consent

        Exclusion Criteria

          -  Patients diagnosed with rheumatoid arthritis or other musculoskeletal diseases
             affecting lower extremities

          -  Relevant effusion in the index knee

          -  Known current or remittent cancer

          -  Carry cardiac pacemaker or defibrillator in situ

          -  Knee surgery in previous 6 months

          -  Received treatment with arthrocentesis

          -  Intra-articular injection of steroids in previous 3 months

          -  Inability to understand instructions or to give informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? 1
Clinical trial: Efficacy and Safety Study of the Combined Modality Therapy in Adenocarcinoma of the Esophago-gastric Junction (NCT01523015)

Eligibility criteria:
Inclusion Criteria:

          -  patients of both gender, aged more than 18, with histopathologically confirmed
             adenocarcinoma of the esophagogastric junction

          -  medically fit to undergo a major surgery with planned thoracotomy and in general
             condition allowing to tolerate chemo- or chemoradiotherapy (Karnofsky Performance
             Status ≥70, ECOG 0-1).

          -  Carcinoma of the esophagogastric junction defined as adenocarcinoma involving
             esophagogastric junction when its epicenter is localized within 5cm proximally or 5cm
             distally to the anatomical esophagogastric junction with subclassification to 3
             topographic types (type I between 5cm and 1cm above; type II between 1cm above and 2cm
             below; type III between 2cm and 5cm below anatomic junction of the esophagus and the
             stomach).

          -  Potentially resectable, local or locoregional cancer with clinical staging
             cT2-4aN0-3M0.

          -  The intended number of randomized patients has been set as 100: 50 patients randomized
             to each therapeutic arm with assumption, that 80% of randomized patients will complete
             the treatment protocol.

        Exclusion Criteria:

          -  disseminated cancer

          -  poor general condition (KI <70)

          -  adenocarcinoma of the stomach

          -  adenocarcinoma of the esophagus
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? 0
Clinical trial: Middle Cerebral To Umbilical Artery Doppler Ratio And Amniotic Fluid Volume Measurement In Post-date Pregnancies in King Khalid Military Central City (NCT02255903)

Eligibility criteria:
Inclusion Criteria:

          1. Singleton, viable fetus in the vertex presentation

          2. History of regular menstrual cycles

          3. Gestational age calculated from the first day of last menstryal period or by
             first-trimester or second-trimester (before 20 weeks) ultrasound examination

          4. No obstetric or medical complications of pregnancy apart from post-date pregnancy

        Exclusion Criteria:

          1. Patients unsure of their dates

          2. Medical disorders with pregnancy as (hypertension, diabetes mellitus or Rh
             isoimmunization)

          3. Prelabor rupture of membranes

          4. Polyhydramnios

          5. Women with multiple pregnancy

          6. Congenital fetal anomalies

          7. Antepartum hemorrhage

          8. Previus cesarean section

          9. Fetal malpresentation
Female
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.
Subject must be at most 48 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? 0
Clinical trial: Different Amoxicillin Treatment Regimens in Erythema Migrans Patients (NCT03966014)

Eligibility criteria:
Inclusion Criteria:

          -  erythema migrans

        Exclusion Criteria:

          -  pregnancy

          -  extracutaneous manifestations of Lyme borreliosis

          -  immunocompromising state

          -  serious adverse event to beta lactam antibiotic

          -  receiving antibiotic with antiborrelial activity within 10 days
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): A 31-year-old woman comes to the office due to 3 days of rash on her left arm.  The lesion is mildly pruritic but not painful.  She is otherwise healthy and occasionally takes ibuprofen during the first few days of her menstrual period.  Temperature is 37 C, blood pressure is 110/75 mm Hg, and pulse is 95/min. The lesion is like a target sign known as erythema migrans. She recently went for an adventure trip in New Hampshire. The patient is diagnosed with Lyme disease.

Patient description (patient's own words): I went to the clinic because I had a rash on my left arm for three days, and the lesion started to be putrid, but it was not painful. I'm a 31-year-old healthy woman and the only medication I use is ibuprofen when I get my periods. They took my temperature, which turned out to be 37°C and took my blood pressure which was 110/75 and my pulse 95. My lesion is round like a target sign. I just came back from a New Hampshire road trip with my friends. Unfortunately, the doctor diagnosed me with Lyme disease.

Does the patient match the trial criteria? 1
Clinical trial: Human Menopausal Gonadotropin (HMG) vs Recombinant Follicle Stimulating Hormone (rFSH) in Gonadotropin Releasing Hormone (GnRH) Antagonist Cycles (NCT00669786)

Eligibility criteria:
Inclusion Criteria:

          -  women with good physical and mental health

          -  aged 18-37 years

          -  regular menstrual cycles ranging from 25 to 35 days; body mass index (BMI) < 30 kg/m2

          -  normal basal serum FSH (≤ 10 IU/L) and E2 (≤ 75 pg/mL) levels determined on the day 3
             of the cycle previous to COH

          -  no uterine (fibroids, adenomyosis, mullerian malformations), ovarian (endometrioma,
             polycystic ovaries) or adnexa (hydrosalpinx) abnormalities assessed by vaginal
             ultrasound.

        Exclusion Criteria:

          -  patients with a history of recurrent pregnancy loss

          -  any significant systemic disease, endocrine or metabolic disorder

          -  having concomitant medication interfering with the purposes of the study

          -  patients who have received any ovulation induction drug within one month before their
             inclusion in the study.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 37 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? 0
Clinical trial: Prevention of Cystitis. (NCT03744338)

Eligibility criteria:
Inclusion Criteria:

          -  Woman aged 18 to 65, consultant in general medicine. (Any patient meeting the
             inclusion criteria may choose to answer the questionnaire in the waiting room of
             general practitioners selected by lot.)

        Exclusion Criteria:

        -
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? 1
Clinical trial: Cough Count Validation (NCT01413698)

Eligibility criteria:
Inclusion Criteria:

          -  Age 2-80 years.

          -  Patients with significant chronic cough.

          -  Patients in hemodynamic stability. Patient is not in respiratory distress.

          -  Subject or subject's parents/guardians is able to comprehend and give informed consent
             for participation in the study.

        Exclusion Criteria:

          -  Contraindication to the use of the PulmoTrack™ or performing ARM (Acoustic Respiratory
             Monitoring).

          -  Hemodynamic instability and/or SOB.

          -  Concurrent additional major illness.

          -  Concurrent participation in any other study.

          -  Physician objection
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient description (patient's own words): I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Does the patient match the trial criteria? 0
Clinical trial: Tomographic Findings in COVID-19 and Influenza (NCT04497311)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with signed informed consent.

          -  Patients with a positive PCR test for SARS-CoV-2 or influenza H1N1 test upon emergency
             department admission.

          -  Patients with lung CT within 24hrs of specimen collection for PCR test.

          -  Patients with complete 30-day follow-up information.

        Exclusion Criteria:

          -  Patients who are unwilling to undergo a lung CT.

          -  Negative PCR test for SARS-CoV-2 or influenza H1N1 test upon emergency department
             admission.

          -  Patients with a tumor or tumor metastasis on the pulmonary CT.

          -  Patients with a previous or de novo autoimmune disease diagnosis.

          -  Patients with a previous or de novo interstitial lung disease.

          -  Pregnancy.

        Elimination Criteria:

          -  Patients with loss of information on the variables of interest.

          -  Patients without 30-day follow-up information.

          -  Patients who chose to withdraw their participation at any time of the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? 0
Clinical trial: Platelet-rich-plasma Treating Tennis Elbow (NCT00757289)

Eligibility criteria:
Inclusion Criteria:

          -  Patient with chronic epicondylitis lateralis who do not react to conservative
             treatment and therefore are send to the orthopedic surgeon

        Exclusion Criteria:
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? 0