araag2/NLI4PR huggingface dataset:
Clinical trial: Vital Signs Patch Early Feasibility and Usability Study (NCT02521922)

Eligibility criteria:
Inclusion Criteria:

          -  Adult male and female in-patients with vital signs considered 'stable' by clinical
             caregivers.

        Exclusion Criteria:

          -  Pediatric patients

          -  Female patients who are pregnant

          -  Patients with internal or external defibrillators

          -  Patients who have undergone surgery and still have a fresh incision on the chest.

          -  Patients with skin damage on the chest such as burns, irritation, infections, wounds,
             etc.

          -  Patients in the Critical Care Unit (CCU)

          -  Patients who otherwise satisfy any of the contraindications associated with the VSP
             system.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor (NCT02692183)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with essential Tremor and unilateral tremor-dominant Idiopathic Parkinson's
             Disease -undergoing ExAblate 4000 Transcranial MR guided focused ultrasound (TcMRgFUS)
             thalamotomy).

        Exclusion Criteria:

          -  In the investigator's opinion, any unstable or clinically significant condition that
             would impair the participants' ability to comply with study requirements.

          -  Patients with significant psychiatric symptoms or history

          -  Treatment with neuroleptics.

          -  Currently with lice or open wounds on scalp.

          -  Significant sensory deficits, e.g., deafness or blindness

          -  Current drug abuse or alcoholism.

          -  Pregnancy or not using a reliable method of birth control
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures (NCT01537770)

Eligibility criteria:
Inclusion Criteria:

          -  VCF on X-ray of the spine (minimal 15% loss of height) level of VCF Th6 or lower

          -  back pain ≤ 8 weeks at time of surgery

          -  ≥ 50 years of age

          -  bone edema on MRI of the fractured vertebral body

          -  focal tenderness on VCF level

        Exclusion Criteria:

          -  severe cardio-pulmonary condition

          -  untreatable coagulopathy

          -  systemic or local infection of the spine (osteomyelitis, spondylodiscitis)

          -  suspected alternative underlying disease (malignancy)

          -  radicular and/or cauda compression syndrome

          -  contra-indication for MRI
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Patient description (medical language): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient description (patient's own words): I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Does the patient match the trial criteria? Entailment
Clinical trial: Effect of Manual Therapies With Supervised Exercise Protocol on Pain and Functional Disability in Patients With Knee OA (NCT04589858)

Eligibility criteria:
Inclusion Criteria:

          -  aged between 47 to 60 years;

          -  mild to moderate pain in one/both knees for 3-months;

          -  the pain intensity score between 2 to 6 on NPRS;

          -  morning stiffness <30-minutes;

          -  Self-reported crepitus on knee motion;

          -  grade 1 to 3 on Kellgren-Lawrence radiographic grading scale for Knee OA

        Exclusion Criteria:

          -  diagnosed case of post-traumatic knee stiffness;

          -  history of bone infection and malignancy (osteomyelitis and tumour); neurological
             disorder (sciatica);

          -  history of joint replacement/meniscal surgery/mechanical knee pain/infection to the
             knee joint; suffering from severe cardiopulmonary disease (chronic obstructive
             pulmonary disease);

          -  Patient showed non-cooperation
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 47 Years old.
Subject must be at most 60 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Contradiction
Clinical trial: Thin Endometrium Undergoing Frozen-thawed Embryo Transfer (NCT04292886)

Eligibility criteria:
Inclusion Criteria:

        1) Younger than 38 years old, basal serum level of follicle stimulating hormone <10 IU / L;
        (2) Endometrium is less than 8mm in at least 2 cycles: superovulation cycle / natural cycle
        / estrogen replacement therapy / ovarian stimulation cycle; (3) at least 1 high quality
        frozen embryo; (4) There are no comorbidities that clearly affect pregnancy, such as
        adenomyosis, endometriosis, and intrauterine adhesions;

        Exclusion Criteria:

          1. abnormal karyotype;

          2. Accompanying other diseases of the uterus: uterine muscular wall myomas that affect
             the uterine cavity shape, more severe adenomyosis, severe endometriosis, congenital
             uterine malformations, endometrial tuberculosis, etc .;

          3. Contraindications to hormone replacement therapy;

          4. Participating in other clinical research;

          5. History of previous fundus diseases;
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 37 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: Prognosis of Signet Ring Cells in Upper Digestive Neoplasms (NCT01249859)

Eligibility criteria:
Inclusion Criteria:

          -  All consecutive patients taken care of, for a proven histologically adenocarcinoma
             (ADCI and ADNCI) of the esophagus, the esogastric junction, or the stomach, in
             surgical or medical oncology investigator centers, will be saved in a given database.

          -  For whom the first consultation took place between January 1997 and January 2010

          -  As they benefit from a medical and/or surgical support (primitive cancer being or not
             resected), whatever the metastatic or the recurrence situation was.

        Exclusion Criteria:

          -  Histological type other than adenocarcinoma

          -  Other localization than esogastric junction, esophagus or stomach
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 95 Years

Patient description (medical language): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient description (patient's own words): I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Does the patient match the trial criteria? Entailment
Clinical trial: Prospective Clinical and Virological Analysis of Healthcare Workers Diagnosed Positive for Covid-19. (NCT04858581)

Eligibility criteria:
Inclusion Criteria:

          -  Healthcare workers over 18 years of age

          -  Healthcare workers who had a diagnosis confirmed by a nasopharyngeal RT-PCR test with
             SARS-CoV-2

          -  Healthcare workers with signed consent

        Exclusion Criteria:

          -  Protected healthcare workers

          -  Pregnant or breastfeeding woman
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction
Clinical trial: Letrozole Versus Clomiphene Citrate for Ovulation Induction in Women With Poly Cystic Ovary Syndrome ( PCOS ) (NCT02551367)

Eligibility criteria:
Inclusion Criteria:

          1. Age between 20-35

          2. Primary or secondary infertility

          3. Patients diagnosed as PCOs according to Rotterdam criteria (Rotterdam
             ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group.,2003)

        Exclusion Criteria:

        Any patients have any causes of infertility other than which mentioned in the inclusion
        criteria as:

          1. Hyperprolactinemia.

          2. Male factor of infertility.

             WHO Guidelines 2010 for Normal seminal fluid analysis :

               -  Volume> 1.5 ml

               -  ph 7.2 to 8.0

               -  Liquefaction time 20 to 30 min

               -  Sperms concentration >15 million/ml

               -  Total motility 40%(Progressive motility + non progressive motility)

               -  Progressive motility 32%

               -  Morphology > 4% normal forms

          3. Thyroid dysfunction.

          4. Diabetes Mellitus.

          5. Known or suspicious tubal factor infertility by HSG or laparoscope.

          6. Endometrioses or pelvic inflammatory diseases .
Female
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 35 Years

Patient description (medical language): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient description (patient's own words): I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Does the patient match the trial criteria? Contradiction
Clinical trial: E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers (NCT00236184)

Eligibility criteria:
Inclusion Criteria:

          1. Male or female patients > 18 years of age.

          2. If female, not of childbearing potential by reason of surgery or menopause, or of
             childbearing potential, but using an approved method of contraception since the last
             menstrual period. Females of childbearing potential must have a negative serum
             pregnancy test before starting the study.

          3. Patients must report a history of heartburn at least two days per week over the past
             month.

        Exclusion Criteria:

          1. History of erosive esophagitis verified by endoscopy.

          2. History of gastroesophageal reflux disease (GERD) diagnosed by a physician.

          3. Patients who have a history of Barrett's esophagus or esophageal stricture.

          4. Evidence of any medical condition that may interfere with the conduct of the study,
             the interpretation of study results, or the health of the patient during the study.

          5. Patients who require continuous use of proton pump inhibitors, histamine receptor (H2)
             blockers, or prokinetics. Prior intermittent use of these agents is permitted if they
             are discontinued at least three days prior to the run-in phase. The H2 blocker,
             cimetidine (Tagamet®), must be discontinued for at least seven days before the study
             drug is administered.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Alternating Current Stimulation for Essential Tremor (NCT04509349)

Eligibility criteria:
Inclusion Criteria:

          -  Participants who meet Diagnostic and Statistical Manual of Mental Disorders criteria
             for ET (APA, DSM V).

          -  18 years of age or older.

          -  Participants should be either un-medicated or on stable medication treatment for
             tremor for the previous 3 months.

          -  Psychiatric comorbidities should be clinically stable; treatment has not changed in
             the last 3 months.

        Exclusion Criteria:

          -  Have a metal object/implant in their brain, skull, scalp, or neck.

          -  Have an implantable device (e.g., cardiac pacemaker).

          -  Have a diagnosis of epilepsy or cardiac disease.

          -  Have a history of traumatic brain injury, learning disability or dyslexia.

          -  Have a severe impediment in vision or hearing.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment