Clinical trial: COVID-19 Study of the Serological Response Against the Severe Acute Respiratory Syndrome (SARS) Coronavirus 2 (CoV-2) Virus in 2 Types of Employees, Hospital and Non-hospital, at Institute Curie and Institute Pasteur (NCT04369066)

Eligibility criteria:
Inclusion Criteria:

          1. Person, adult volunteer outside of any acute infectious episode with SARS-CoV-2* (see
             paragraph indication), working at the Institute Curie and able to exercise their
             professional activity on one of the 3 sites of the Institute Curie: Paris, Orsay or
             Saint Cloud, or on the Campus of the Institute Pasteur.

          2. Person aged 18 or over.

          3. Information and consent of the person to the procedures related to the study (cf.
             information note / consent).

        From November 2020, person having presented at least one of the following criteria since
        January 2020:

          -  A positive diagnostic test for SARS-COV-2 by PCR on a nasopharyngeal sample or
             antigenic test,

          -  A positive SARS-CoV-2 serology,

          -  An anosmia or / and an ageusia,

          -  A respiratory infection ** associated with digestive signs **

        whatever the working methods during confinement * Subjects who are not showing active
        SARS-CoV-2 infection are considered volunteers at the time of inclusion: people with no
        clinical signs ** suggestive of SARS-CoV-2 infection at the time of collection or having
        had an end of symptoms for more than 7 days [1].

        ** fever, fatigue, cough, shortness of breath, difficulty to breath, loss of taste or
        smell, headache, body aches, conjunctivitis or cold, digestive problems (vomiting,
        diarrhea), whether or not the signs led to sick leave, treatment and / or hospitalization
        [2].

        Exclusion Criteria:

          -  Declaration by the subject of signs suggestive of Coronavirus Infectious Disease 2019
             (COVID-19) infection with SARS-CoV-2 in progress or for which the end of symptoms
             dates from less than 7 days

          -  Inability to submit to study monitoring for geographic, social or psychological
             reasons
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Patient description (medical language): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient description (patient's own words): I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Does the patient match the trial criteria? Contradiction