araag2/NLI4PR huggingface dataset:
Clinical trial: Study of DHT-Gel to Treat the Symptoms of Low Testosterone in Men 55-80 (NCT00163566)

Eligibility criteria:
Inclusion Criteria:

          -  Men aged 55-80 Serum Testosterone > 275 Symptoms of Hypogonadism as determined by AMS
             scale In good overall health

        Exclusion Criteria:

          -  Abnormal Prostate Exam for age Prostate or Breast Cancer Significant illness Weight
             >300lbs Generalized skin disease Unstable sleep apnea
Male
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth (NCT00750828)

Eligibility criteria:
Inclusion Criteria:

          -  For test group dry mouth complaints and with a diagnosis ofSjogren's Syndrome

        Exclusion Criteria:

          -  Other medical problems that effect salivary glands
Female
No healthy subjects accepted to join the trial.
Subject must be at least 46 Years old.
Subject must be at most 56 Years

Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? Entailment
Clinical trial: Medical Imaging in the Diagnosis of Ganglion Cysts of the Hand (NCT04416828)

Eligibility criteria:
Inclusion Criteria:

          -  Flexor tendon sheath ganglion cyst

          -  Dorsal ganglion cyst

          -  Palmar ganglion cyst

          -  Male and female patients minimum age 18 years

          -  MRI of the affected area

        Exclusion Criteria:

          -  Pregnancy, lactation

          -  Malignant disease

          -  Insufficient mental possibility of cooperation

          -  Medical, psychiatric or other conditions that restrict the patient's following
             abilities: to interpret the study information, to give informed consent, to adhere to
             the rules of the protocol, or to complete the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient description (patient's own words): I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Does the patient match the trial criteria? Entailment
Clinical trial: Thunderbeat Technology vs Standard Bipolar Electro-surgery in Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for Endometrial Cancer (NCT01717794)

Eligibility criteria:
Inclusion/Exclusion Criteria:

          -  Age ≤ 75 years

          -  Patient's informed consent

          -  American Society of Anesthesiologists: < class III or IV

          -  No actual pregnancies or P.I.D.

          -  No previous major abdominal surgical procedures

          -  Endometrial cancer FIGO stages IB-II

          -  Endometrioid histotype

          -  No previous radiotherapy on pelvic fields

          -  No uterine size larger than conform 10 weeks gestation
Female
No healthy subjects accepted to join the trial.

Subject must be at most 75 Years

Patient description (medical language): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient description (patient's own words): I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Does the patient match the trial criteria? Contradiction
Clinical trial: Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection (NCT02835521)

Eligibility criteria:
Inclusion Criteria:

          -  knee osteoarthritis according to american college of rheumatology criteria

          -  no previous experience of joint injection

          -  stable use of drugs for osteoarthritis treatment for at least 3 months

          -  stable dose of corticosteroids, non hormonal anti-inflammatory and analgesics in the
             previous month

          -  pain on knee between 3 and 7 in the visual analogue scale

          -  signe the informed consent term

          -  radiologic classification between 1-3 (kellgren and Lawrence classification)

        Exclusion Criteria:

          -  joint disease of different etiology

          -  coagulation alteration

          -  non treated fibromyalgia

          -  litigation

          -  diabetes mellitus and systemic arterial hypertension out of control

          -  allergy of lidocaine or triamcinolone hexacetonide
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 85 Years

Patient description (medical language): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient description (patient's own words): I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Does the patient match the trial criteria? Contradiction
Clinical trial: Screening and Characterization of Hearing Disorders in Diabetic Persons (NCT03437135)

Eligibility criteria:
Inclusion Criteria:

          -  type 1 or type 2 diabetic patients

        Exclusion Criteria:

          -  history of otological surgical act

          -  presence of neurological or psychiatric disorders that may impair the quality of
             explorations

          -  presence of a obstructive wax stopper or au foreign body found in the simple otoscopy
             (or impossibility of this extraction).
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient description (patient's own words): I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Does the patient match the trial criteria? Entailment
Clinical trial: Demand-driven Management of Essential Tremor (NCT02443181)

Eligibility criteria:
Inclusion Criteria:

          -  Appropriate candidates for DBS with essential tremor

        Exclusion Criteria:

          -  Not meeting inclusion criteria based on tremor amplitude, neuropsychological testing,
             etc.

          -  Prior trauma to the brain on side of putative implantation of stimulator
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment
Clinical trial: Pilot Feasibility Study of a Sjögren's Syndrome Self-management App (NCT04653935)

Eligibility criteria:
Inclusion Criteria:

          -  Over 18 years of age

          -  Diagnosed with either Primary or Secondary Sjogren's syndrome (self-report)

          -  Own an iPhone or Android smartphone

        Exclusion Criteria:

          -  None
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient description (patient's own words): I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Does the patient match the trial criteria? Entailment
Clinical trial: Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism (NCT02380755)

Eligibility criteria:
Inclusion Criteria:

          -  ADAM questionnaire positive for 3 or more questions

          -  Total serum Testosterone lower than 300 ng/dL in two different occasions, within a
             1-week minimum interval. This blood sample must be collected between 8 and 11 a.m.

          -  Low or Inappropriate normal serum Luteinizing hormone (LH) level

          -  ATP III Metabolic Syndrome Criteria

          -  Obesity - BMI over 30 kg/m2

        Exclusion Criteria:

          -  Systemic illness, such Rheumatoid Arthritis, Cushing disease, liver insufficiency or
             renal insufficiency. -Use of certain medications (opiates, high-dose glucocorticoid
             therapy, methadone)

          -  Eating disorders

          -  Testicular volume below 4 mL

          -  Use of recreational drugs

          -  Excessive exercise practice

          -  Men in treatment for prostatic cancer

          -  Hyperprolactinaemia

          -  Hemochromatosis

          -  History of headache

          -  Systolic blood pressure lower than 100 mmHg

          -  Previous adverse reactions to nitrate compounds

          -  Diabetes over 10 years of diagnosis
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Patient description (medical language): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient description (patient's own words): I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Does the patient match the trial criteria? Contradiction
Clinical trial: Wearable Sensor for Responsive DBS for ET (NCT03051178)

Eligibility criteria:
Inclusion Criteria:

          -  Provide informed consent

          -  Patient is over 21 years of age

          -  Patient has had a significant disabling, medication-refractory upper extremity tremor
             with no evidence of non-ET central nervous system disease or injury for at least three
             (3) months prior to implantation of Activa SC, PC, or RC device.

          -  Patient receives Vim electrode and Activa SC, PC or RC device implants, and recovers
             fully after surgery.

          -  Patient is available for study participation after their clinical programming
             appointments for six months.

        Exclusion Criteria:

          -  Medication related movement disorders.

          -  Any suspicion of Parkinsonian tremor, including presence of Parkinsonian features such
             as bradykinesia, rigidity, or postural instability.

          -  Severe medical co-morbidity including cardiovascular disorder, lung disorder, kidney
             disease, continuous neurological disease, hematological disease, or frailty that
             impact tolerability of the surgery as judged by the screening physicians.

          -  Patient is undergoing a lead revision surgery.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient description (patient's own words): I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Does the patient match the trial criteria? Entailment