araag2/NLI4PR huggingface dataset:
Clinical trial: Minimal Change Esophagitis by i-Scan Endoscopy in Dyspeptic Patients (NCT01742377)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with one or more of the following symptoms namely epigastric pain or
             discomfort, postprandial fullness and early satiety with or without symptoms
             suggesting GERD

          -  Patients able to give informed consent

        Exclusion Criteria:

          -  Patients with significant weight loss.

          -  Patients with hematemesis, melena ,dysphagia, intractable vomiting , palpable
             abdominal mass.

          -  Patients with history of documented peptic ulcer , gastric surgery , gastric cancer.

          -  Patients with symptoms compatible with irritable bowel syndrome, hepatobiliary tract
             disease.

          -  Patients with severe concomitant medical conditions, pregnant woman or continuous
             usage of steroids or NSIADS in the preceding 1 month before entry to the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient description (patient's own words): I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Does the patient match the trial criteria? Entailment
Clinical trial: Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission. (NCT03244709)

Eligibility criteria:
Inclusion Criteria:

        - All consecutive patients meeting the 1990 ACR classification criteria for GCA.

        Exclusion Criteria:

          -  Corticosteroid treatment during the previous 6 months.

          -  Uncontrolled diabetes.

          -  Uncontrolled hypertension.

          -  History of cancer within the past 5 years.

          -  History of frequent infections in the past.

          -  Positivity of screening procedures for latent tuberculosis infection.

          -  Uncontrolled dyslipidemia at baseline.

          -  Known intestinal diverticulosis.

          -  Concomitant hematologic disorders.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient description (patient's own words): I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Does the patient match the trial criteria? Entailment
Clinical trial: Ultrasound Guided Artificial Insemination (NCT00809952)

Eligibility criteria:
Inclusion Criteria:

          -  The woman's inclusion criteria in our IUI program were at least one patent tube,
             normal cavity, basal FSH < 10 mU/mL and age under 40 years.

          -  IUI with husband's sperm (IUI-H) was indicated when, after sperm preparation, at least
             5 million motile spermatozoa were recovered; this was performed in 58 cases (79.45%).

          -  In the remaining 15 cases (20.55%), IUI was performed with donor sperm (IUI-D) either
             because of azoospermia (n=6) failure to recover spermatozoa during testicular biopsy
             (n=5) or in women without a male partner (n=4).

        Exclusion Criteria:

          -  Previous infertility treatments had been carried out.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Patient description (medical language): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient description (patient's own words): I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Does the patient match the trial criteria? Contradiction
Clinical trial: Effect of Glucomannan Supplementation on Body Weight in Overweight and Obese Children (NCT02280772)

Eligibility criteria:
Inclusion Criteria:

          -  age 6-17 years;

          -  overweight or obesity based on the WHO (World Health Organization) growth
             charts/references (>+1 standard deviation [SD] or >+2 SD, respectively)

        Exclusion Criteria:

          -  drug therapy for a chronic disease (including drugs that influence appetite or body
             weight);

          -  type 1 or 2 diabetes;

          -  history of surgical treatment of obesity;

          -  participation in another program for treating obesity during the project and/or 3
             months prior to recruitment;

          -  secondary causes of obesity;

          -  pregnancy.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 6 Years old.
Subject must be at most 17 Years

Patient description (medical language): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient description (patient's own words): I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Does the patient match the trial criteria? Entailment
Clinical trial: Clinical and Laboratory Characteristics of Patients Admitted With Syncope; Diagnosis and Follow up After These Patients (NCT01201993)

Eligibility criteria:
Inclusion Criteria:

          -  patients with diagnosis of syncope on admission to the medical ward.

        Exclusion Criteria:

          -  patients with loss of consciousness due to other than low perfusion of the brain

          -  patients that can't sign a consent form

          -  patients that we can't get details about the episode of the syncope
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: HIV Testing in the Emergency Department at Baystate Medical Center: A Pilot Program (NCT00987194)

Eligibility criteria:
Inclusion Criteria:

          -  Emergency department patients aged 18 years or older, appropriate for HIV testing will
             be identified by the HIV health educator.

          -  Patients who are not otherwise occupied and who are not known to be HIV+ will be
             approached for consent to the study and for rapid HIV testing.

        Exclusion Criteria:

          -  None.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient description (patient's own words): I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Does the patient match the trial criteria? Entailment
Clinical trial: Cardiovascular Status in Patients With Endogenous Cortisol Excess (Cushing's Syndrome) (NCT03880513)

Eligibility criteria:
Inclusion Criteria:

          -  Written informed consent

          -  Age ≥18 years

          -  Cross-sectional study:History of clinically and biochemically proven endogenous
             Cushing's syndrome (overt or subclinical)

          -  Longitudinal study: Patients with clinically and biochemically proven endogenous
             Cushing's syndrome (initial diagnosis or recurrent disease)

        Exclusion Criteria:

          -  Glucocorticoid pharmacotherapy for >12 months within the previous 3 years

          -  Structural heart disease, chronic heart failure (>NYHAII), systemic or single organ
             disease potentially affecting cardiac function

          -  Arterial hypertension (uncontrolled with >3 antihypertensive drugs)

          -  Pregnancy

          -  Drug abuse

          -  Cardiac Magnetic Resonance Imaging (cMRI) substudy: patients with renal failure are
             excluded from the cMRI study (MDRD <60)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Patient description (medical language): A 47-year-old man comes to the office due to weight gain and fatigue.  He is not able to lift heavy objects or climb stairs. Family history is positive for DM type 2 and HTN in his father.  Blood pressure is 165/90 mm Hg and pulse is 85/min.  On physical examination, there is symmetric proximal muscle weakness of the upper and lower extremities.  Fasting plasma glucose level is 138 mg/dL and 24-hour urinary cortisol is twice the upper normal limit.  Further evaluation reveals that high-dose, but not low-dose, dexamethasone suppresses serum cortisol levels.  Serum ACTH levels are high-normal. This patient's findings are consistent with endogenous Cushing Syndrome.

Patient description (patient's own words): I'm a 47-year-old man. I went to the clinic because I had been gaining weight and had increased fatigue over the past few weeks. I was not able to lift heavy objects or even climb the stairs. My dad was diagnosed with type 2 diabetes and high blood pressure. During the exam, they took my blood pressure, which was 165/90 mm Hg, and my pulse was 85/min. They found out that I have weaknesses in both of my arms and legs. I also did a blood test on an empty stomach, and I had a glucose level of 138 mg/dL, and twice the upper normal limit of cortisol. I had high-normal levels of ACTH. The doctor said I suffer from endogenous Cushing Syndrome.

Does the patient match the trial criteria? Entailment
Clinical trial: Validation of the San Francisco Syncope Rule (NCT00300625)

Eligibility criteria:
Inclusion Criteria: Acute syncope or near syncope as a reason for the ED visit

        Exclusion Criteria: Altered mental status, alcohol or illicit drug-related loss of
        consciousness, Definite seizure, Transient loss of consciousness caused by head trauma
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.


Patient description (medical language): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient description (patient's own words): I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Does the patient match the trial criteria? Entailment
Clinical trial: Detection of Pleural Effusion by Internal Thoracic Impedance Method (NCT01601444)

Eligibility criteria:
Inclusion Criteria:

          -  Inclusion criteria for study group will be as follows: patients 40-90 year old with
             pleural effusion on chest X-ray of different etiologies:

               -  coronary heart disease-(CHD)

               -  valvular heart disease

               -  renal failure

               -  infectious disease malignant diseases( all complicated by pleural effusion).

          -  The control group will be comprised of patients 40-90years old without pleural
             effusion established by chest X-ray.

        Exclusion Criteria:

          -  The exclusion criteria will be respiratory failure due to diseases, wearing a
             pacemaker,thoracic deformation, pulmonary edema and embolism
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 90 Years

Patient description (medical language): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient description (patient's own words): I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Does the patient match the trial criteria? Entailment
Clinical trial: Efficacy and Mechanisms of Energy Medicine to Decrease Chronic Knee Pain in Outpatient Settings (NCT03637595)

Eligibility criteria:
Inclusion Criteria:

          -  Presence of knee pain lasting for at least six months

          -  No radiation of knee pain

          -  No acupuncture treatments in the previous six months

          -  Failure to respond completely to the medications given by their orthopedic or pain
             management specialist

          -  Knee pain on most days (4 out of 7 days of the week) with average self-reported
             severity of 4 or more out of 10 on a numeric rating scale (NRS)

          -  Complaints of morning stiffness lasting less than 30 minutes

          -  Not be in active physical therapy (PT) for the duration of the trial.

          -  Adult patients ≥18 years of age

          -  English speaking

        Exclusion Criteria:

          -  Any concurrent diagnosis of systemic disease

          -  Other concurrent treatments such as massage, Acupcunture, PT or any kind of Energy
             Medicine

          -  Bleeding disorder

          -  Trypanophobia (fear of needles or injections).

          -  Have medical condition that causes difficulty in saliva production/collection (i.e.:
             Sjogren's Syndrome)
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Patient description (medical language): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient description (patient's own words): I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Does the patient match the trial criteria? Contradiction