Clinical trial: Blood Flow Restriction Exercise in the Treatment of Lateral Epicondylalgia Traditional Treatment (NCT04607356)

Eligibility criteria:
Inclusion Criteria:

          1. Diagnosis of lateral elbow pain (e.g. "tennis elbow" or wrist extensor tendinopathy)

          2. Between the ages of 18-65

          3. Elbow pain for 4 weeks or more

        Exclusion Criteria:

          1. Ligamentous elbow sprain, osteoarthritis of elbow and cervical radiculopathy in the
             affected limb will be excluded from the study.

          2. Any history of ligamentous, bony or other soft tissue reconstruction surgery at the
             affected elbow.

          3. Vascular disorders to include: history of DVT, history of endothelial dysfunction,
             peripheral vascular disease

          4. Injection therapy (corticosteroid, platelet rich plasma, or other injection therapy)
             in the prior 3 months to the affected site

          5. Current fracture in affected arm

          6. History of crush injury to affected arm

          7. Any surgery on affected arm in last 1 year

          8. Surgery within last year on contralateral upper extremity

          9. History of lymphectomy (such as axillary exploration with breast surgery, lymph node
             biopsy in the affected axilla/arm)

         10. Pregnancy

         11. Active infection

         12. Current cancer diagnosis/treatment

         13. Sickle cell anemia or trait

         14. Kidney dialysis

         15. History of syncope/passing out with pressure to body (such as massage, or blood
             pressure cuff).

         16. Inability to consent

         17. Thromboembolism

         18. Regular tobacco use in the past 6 months

         19. Varicose veins

         20. Cardiovascular disorders

         21. Taking anti-coagulant medications

         22. Bleeding disorder

         23. Instructed by a physician or medical practitioner that they are not cleared to
             exercise
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Patient description (medical language): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient description (patient's own words): I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Does the patient match the trial criteria? Contradiction