Clinical trial NCT00696657 (phase 2, status: completed)
Conditions: diabetes, diabetes mellitus, type 2
ICD codes: E23.2, N25.1, P70.2, O24.92, Z83.3, Z86.32, E10.65, E11.65, E11.9, E11.21, E11.36, E11.41, E11.42, E11.44
Drugs: semaglutide, semaglutide, semaglutide, semaglutide, semaglutide, semaglutide, placebo, placebo, placebo, placebo, placebo, liraglutide, liraglutide
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Eligibility criteria:

        Inclusion Criteria:

          -  Men and women-not-of-childbearing potential diagnosed with type 2 diabetes for at
             least three months

          -  Stable treatment regimen with either metformin (at least 1500 mg) or diet and exercise
             alone for at least three months

          -  HbA1c: 7.0-10.0 % (both inclusive)

          -  Body weight between 60 kg and 110 kg

        Exclusion Criteria:

          -  Treatment with insulin, GLP-1 receptor agonists (including liraglutide), dipeptidyl
             peptidase-4 inhibitors, sulphonylurea, thiazolidinediones, Alpha-GIs, or any
             investigational drug, within the last three months

          -  Impaired liver or kidney function

          -  Proliferative retinopathy or maculopathy requiring acute treatment

          -  Clinically significant active cardiovascular disease and uncontrolled
             treated/untreated hypertension

          -  Recurrent major hypoglycaemia or hypoglycaemic unawareness

          -  Present or planned use of any drug which could interfere with the glucose levels (e.g.
             systemic corticosteroids)