Availability Of Over-The-Counter Narcan Could Help As A Tool To Combat The Illicit Fentanyl Crisis, But Affordability Remains An Issue Narcan nasal spray is the first naloxone product to formally be available OTC. While it may take months before Narcan becomes available OTC - and once in pharmacies as an off-the-shelf product its price could keep it out of reach  for many - this still represents an important regulatory action.