Newly Approved Brexafemme, A Unique Treatment For Vaginal Yeast Infections, May Face Uptake Hurdles Newly approved Brexafemme is a unique treatment for vaginal yeast infections. But, at Brexafemme's estimated list price of between $350 and $450 uptake will face hurdles, including payer step edits that limit use to women who don't respond to azole antifungals or have azole-resistant infections.