Question: What is the name given to a north-south US Route in the eastern United States which extends for 680 miles from an interchange with New York State Route 17 in Pennsylvania, to an intersection with US 1 in North Carolina, passing a populated place known as Emery 50 miles south of Greensboro?
Context: U.S. Route 301 (US 301) is a part of the U.S. Highway System that runs from Sarasota, Florida to Middletown, Delaware.  In Virginia, the U.S. Highway runs 142.70 mi from the North Carolina state line near Skippers north to the Maryland state line at the Potomac River near Dahlgren.  US 301 forms the local complement to Interstate 95 (I-95) from Emporia to Petersburg.  The U.S. Highway runs concurrently with US 1 between Petersburg and the state capital of Richmond, where the highways form one of the main north–south avenues.  US 301 continues north concurrent with Virginia State Route 2 (SR 2) to Bowling Green, forming an eastern alternative to I-95 and US 1 north of Richmond.  At Bowling Green, which is connected to I-95 by SR 207, US 301 becomes the primary highway connecting Richmond and the Northern Neck with Southern Maryland.  US 301 was constructed in four main segments: as the original SR 24 and then US 17-1 south of Petersburg, as US 1 from Petersburg to Richmond, as SR 2 from Richmond to Bowling Green, and as part of SR 207 toward Dahlgren.  US 301 replaced US 17-1 in the early 1930s and was extended from Petersburg north along its current course into Maryland when the Potomac River Bridge was completed in 1940. Emery, North Carolina is a populated place in Montgomery County, North Carolina, in the United States.  It is located along the co-designated Interstate 73 - Interstate 74, about 50 miles south of Greensboro where the interstates meet U.S. Route 220.  It is approximately equidistant between Raleigh to the east and Charlotte to the west.  Its ZIP code is 27281.  Its elevation is 682 feet above mean sea level. U.S. Route 15 (US 15) is a part of the U.S. Highway System that runs from Walterboro, South Carolina, to Painted Post, New York.  In the U.S. state of New York, US 15 extends 12.68 mi through the Southern Tier from the Pennsylvania state line at Lindley north to an interchange with the Southern Tier Expressway (Interstate 86 and New York State Route 17) just outside Painted Post.  US 15 originally continued north to Rochester before being truncated to its present northern terminus.  All of US 15 in New York was designated as I-99 on June 27, 2014. New York State Route 17K (NY 17K) is an east–west state highway located within Orange County, New York, in the United States.  It extends for 22.01 mi from an intersection with NY 17 east of Bloomingburg to a junction with U.S. Route 9W (US 9W) midway across the city of Newburgh.  The western terminus was where NY 17K originally connected to its parent route, NY 17; it now meets NY 17 a short distance to the east at an interchange with the Quickway.  In Newburgh, NY 17K becomes Broadway and serves as the city's primary east–west street.  The road can be divided into a half west of Montgomery, where it runs through relatively undeveloped land, and an eastern half where it closely parallels Interstate 84 (I-84) and serves much more populated areas. U.S. Route 220 (US 220) is a north–south U.S. Route in the eastern United States.  The highway extends for 680 mi from an intersection with US 1 in Rockingham, North Carolina, to its interchange with New York State Route 17 (NY 17; future Interstate 86 or I-86) in South Waverly, Pennsylvania.  Some sections of the route are part of the Appalachian Development Highway System's Corridor O as well as I-73 in North Carolina.  US 220 is a spur route of US 20; however, the two routes do not intersect nor do they connect via other spurs of US 20. New York State Route 79 (NY 79) is an east–west state highway in the Southern Tier of New York, in the United States.  The western terminus of the route is at the intersection with NY 414 near the southern end of Seneca Lake just northeast of Watkins Glen.  Its eastern terminus is at the Pennsylvania state line in the town of Windsor in Broome County, where it connects to Pennsylvania Route 92 (PA 92).  NY 79 passes through three regions; it starts in the Finger Lakes region, runs through Central New York and ends on the western fringes of the Catskills.  The route is signed east–west, but from Whitney Point to the state line it runs in a north–south orientation and is signed north-south a few miles south of Center Village, a hamlet that is a few miles south of Harpursville. Interstate 88 (I-88) is an intrastate Interstate Highway located entirely within the U.S. state of New York.  Nominally an east-west road as it has an even number, it extends for 117.75 mi in a northeast–southwest direction from an interchange with I-81 north of Binghamton to an interchange with the New York State Thruway (I-90) west of Schenectady.  The freeway serves as an important connector route from the Capital District to Binghamton, Elmira (via New York State Route 17 or NY 17, future I-86), and Scranton, Pennsylvania (via I-81).  I-88 closely parallels NY 7, which was once the main route through the area. New York State Route 115 (NY 115) is a 12.45 mi long state highway located entirely within Dutchess County, New York.  The route runs from an intersection with U.S. Route 44 (US 44) and NY 55 in the city of Poughkeepsie along the former Salt Point Turnpike to an interchange with the Taconic State Parkway in Clinton.  Throughout its length NY 115 is maintained by the city of Poughkeepsie, Dutchess County (as CR 75), and the New York State Department of Transportation.  When NY 115 terminates at the Taconic State Parkway, the Salt Point Turnpike continues as County Route 17 (CR 17) for another four miles to NY 82 in Stanford. Route 17 is a state highway in Bergen County, New Jersey, United States, that provides a major route from the George Washington Bridge, Lincoln Tunnel and other northeast New Jersey points to the New York State Thruway at Suffern, New York.  It runs 27.20 mi from Route 7/County Route 507 in North Arlington north to the New York border along Interstate 287 in Mahwah, where New York State Route 17 continues into New York.  Between Route 7 and Route 3 in Rutherford, Route 17 serves as a local road.  From Route 3 north to the junction with U.S. Route 46 in Hasbrouck Heights, the road is a suburban arterial with jughandles.  The portion of Route 17, from US 46 to Interstate 287 near the state line in Mahwah, is a limited-access road with all cross traffic handled by interchanges, and many driveways and side streets accessed from right-in/right-out ramps from the right lane.  For three miles (5 km) north of Route 4, well over a hundred retail stores and several large shopping malls line the route in the borough of Paramus.  The remainder of this portion of Route 17 features lighter suburban development.  The northernmost portion of Route 17 in Mahwah runs concurrent with Interstate 287 to the New York border. U.S. Route 220 (US 220) is a U.S. Highway that runs from Rockingham, North Carolina north to South Waverly, Pennsylvania.  In the state of Pennsylvania, the route runs 248 mi from the Maryland border in Cumberland Valley Township, Bedford County northeast to an interchange with Interstate 86 (I-86)/New York State Route 17 (NY 17) in South Waverly, Bradford County a short distance south of the New York border.  Through the state, US 220 passes through the cities and towns of Bedford, Altoona, State College, Lock Haven, Williamsport, and Towanda.  US 220 is concurrent with the entire completed Pennsylvania segment of I-99 between I-70/I-76 (Pennsylvania Turnpike) in Bedford and I-80 near Bellefonte.  US 220 is also a freeway around Bedford, along the I-80 concurrency between Bellefonte and Mill Hall, between Mill Hall and Jersey Shore, from the western end of Williamsport to near Halls (where it is concurrent with I-180 east of downtown Williamsport), and near the New York border.  The remainder of US 220 in Pennsylvania is mostly a two-lane surface road.
Answer: U.S. Route 220