Question: Painkiller Jane is a fictional character, a comic book heroine created by Jimmy Palmiotti and Joe Quesada for Event Comics in 1995, Originally a five-issue mini-series, the character went on to star in numerous crossover titles with the likes of which fictional character appearing in American comic books published by Marvel Comics?
Context: Ash is an American comic book character created by Joe Quesada and Jimmy Palmiotti, published by Event Comics about a firefighter who gains superpowers from a time-displaced regeneration device from a possible apocalyptic future. Namor the Sub-Mariner ( ) (Namor McKenzie) is a fictional character appearing in American comic books published by Marvel Comics.  Debuting in early 1939, the character was created by writer-artist Bill Everett for Funnies Inc., one of the first "packagers" in the early days of comic books that supplied comics on demand to publishers looking to enter the new medium.  Initially created for the unreleased comic "Motion Picture Funnies Weekly", the Sub-Mariner first appeared publicly in "Marvel Comics" #1 (cover-dated Oct. 1939) – the first comic book from Timely Comics, the 1930s–1940s predecessor of the company Marvel Comics.  During that period, known to historians and fans as the Golden Age of Comic Books, the Sub-Mariner was one of Timely's top three characters, along with Captain America and the original Human Torch.  Everett said the character's name was inspired by Samuel Taylor Coleridge's poem, "The Rime of the Ancient Mariner".  Everett came up with "Namor" by writing down noble sounding names backwards and thought Roman/Namor looked the best. Carlie Cooper is a fictional character appearing in American comic books published by Marvel Comics.  The character appears in comic books centered on Spider-Man.  She is named after Joe Quesada's daughter.  Carlie is friends with Peter Parker (Spider-Man), Harry Osborn, Vin Gonzales, and Lily Hollister.  She is one of the first potential romantic interests for Parker following his long relationship with Mary Jane Watson in the "" story arc and eventually becomes his girlfriend for a time. Painkiller Jane is a fictional character, a comic book heroine created by Jimmy Palmiotti and Joe Quesada for Event Comics in 1995.  Originally a five-issue mini-series, the character went on to star in numerous crossover titles with the likes of the Punisher, Vampirella, and Hellboy.  Recently, the series relaunched at Dynamite Entertainment with the first issue selling out.  The comics have been the basis for a film and television series. Event Comics was an American independent comic book publisher founded by veteran artists Jimmy Palmiotti and Joe Quesada.  The company published during the years 1994 to 1999, at which point it was contracted to form the Marvel Knights imprint for Marvel Comics. Thomas Logan is a fictional character appearing in American comic books published by Marvel Comics.  The character has been depicted as the biological father of X-Men member Wolverine.  He was created by Bill Jemas, Joe Quesada, and Paul Jenkins.  He was featured in the limited series "Origin", which detailed the youth and formative years of Wolverine and was published from November 2001 to July 2002. Echo (Maya Lopez), also known as Ronin, is a fictional character, a superheroine appearing in American comic books published by Marvel Comics.  The character has been depicted as a supporting character of Daredevil.  She makes her first appearance in "Daredevil" Vol.  2, #9 (Dec.  1999), and was created by David Mack and Joe Quesada.  She is a Native American and one of the very few deaf comic characters. Captain America is a fictional character appearing in American comic books published by Marvel Comics.  Created by cartoonists Joe Simon and Jack Kirby, the character first appeared in "Captain America Comics" #1 (cover dated March 1941) from Timely Comics, a predecessor of Marvel Comics.  Captain America was designed as a patriotic supersoldier who often fought the Axis powers of World War II and was Timely Comics' most popular character during the wartime period.  The popularity of superheroes waned following the war and the "Captain America" comic book was discontinued in 1950, with a short-lived revival in 1953.  Since Marvel Comics revived the character in 1964, Captain America has remained in publication. Marvel Knights was an imprint of Marvel Comics that contained material taking place just outside the Marvel Universe (Earth-616).  The imprint originated in 1998 when Marvel outsourced four titles ("Black Panther", "The Punisher", "Daredevil", and "The Inhumans") to Joe Quesada and Jimmy Palmiotti's company Event Comics; Event hired the creative teams for the Knights line while Marvel published them. The Punisher (Francis "Frank" Castle) is a fictional character appearing in American comic books published by Marvel Comics.  The character was created by writer Gerry Conway and artists John Romita Sr. and Ross Andru, with publisher Stan Lee green-lighting the name.  The Punisher made his first appearance in "The Amazing Spider-Man" #129 (cover-dated Feb. 1974).
Answer: Punisher