Question: Where are the headquarters of the company that developed Crizanlizumab?
Context: The Hackensack Water Company Complex is a set of historic buildings in Weehawken, New Jersey, registered in the U.S. National Register of Historic Places.  The Hackensack Water Company, a predecessor of Suez North America, developed water supply and storage in northeastern New Jersey from the 1870s to the 1970s, initially to provide service to the city of Hackensack and the towns of North Hudson.  Originally its headquarters and major facilities were located at Hackensack, in Bergen County.  Under Robert W. de Forest, who ran the Hackensack Water Company for 46 years beginning in 1881, the company constructed new facilities and moved its headquarters to Weehawken in Hudson County, setting up offices in a brick water tower, part of the present complex. Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.  It is one of the largest pharmaceutical companies by both market cap and sales. Appaloosa Interactive (formerly Novotrade International) was a corporation, founded in 1982 in Hungary, that produced numerous video games, computer programs and television commercials during the 1980s and 1990s.  Novotrade International was founded by Andras Csaszar and Stephen J. Friedman.  Csaszar served as the company's president, while Friedman served as chief executive officer.  Novotrade began operating branches in the United States in 1989, and was renamed Appaloosa Interactive in November 1996.  That month, the company unveiled its 10-month-old Internet technologies division, Appaloosa Online.  The company's headquarters were in Mountain View, California.  Appaloosa was the parent company and owner of two software development companies in Budapest, Hungary.  Appaloosa was well known for its "Ecco the Dolphin" game series for Sega.  Appaloosa also developed two "Contra" games on the PlayStation and Sega Saturn for Konami. Crizanlizumab is a monoclonal antibody developed by Novartis targeted towards P-selectin.  It was announced by the company as an effective drug to prevent vaso-occlusive crisis in patients with Sickle cell anemia.  The result of the Phase II SUSTAIN clinical trial was published on December 3, 2016 which showed the efficacy of the drug in sickle cell patients.  Trial was conducted among 196 patients over 12 months which showed reduction in annual rate of sickle cell crises by 45% compared to the placebo group. Windber Historic District is a national historic district located at Paint Borough, Scalp Level, and Windber in Cambria County and Somerset County, Pennsylvania.  The district includes 944 contributing buildings and 1 contributing site.  It encompasses an area first developed by the Berwind-White Coal Company in 1897, and developed and between 1897 and 1930.  It includes the central business district of Windber and surrounding residential areas, consisting largely of workers' housing.  Notable buildings include the Berwind-White Headquarters Building (1903), Eureka Department Store (1899), Windber Trust Company (1910), Windber Electric Building (1925), Clement Building (1902), Windber Hotel (1902), former train station (1916), Arcadia Theater (1919), Clubhouse (1899), Davis Shaffer House (now Windber Museum, 1886), and Windber Hospital (c. 1905). Alliance Boots GmbH was a multinational pharmacy-led health and beauty group with corporate headquarters in Bern, Switzerland and operational headquarters in Nottingham and Weybridge, United Kingdom.  The company had a presence in over 27 countries including associates and joint ventures and in 2013/14, reported revenue in excess of £23.4 billion.  It had two core business activities – pharmacy-led health and beauty retailing, and pharmaceutical wholesaling and distribution – and also increasingly developed and internationalised its product brands. Servomechanisms, Inc. was a Cold war era U.S. defense sub-contractor, which developed precision sub-systems for high performance jet aircraft, guided missiles and ballistic missiles.  Most widely publicised was the company's role in development of the Army Redstone missile under the auspices of the Army Ballistic Missile Agency.  95% of the company's business was military-related.  Company headquarters as well as its main production lines were located at 12500 Aviation Blvd., Hawthorne, California.  In 1964, Teledyne Industries, Inc. purchased Servomechanisms, Inc., which became Teledyne Systems Company, Controls Systems Division, having its office relocated at 200 North Aviation Blvd., El Segundo, California. ThetaRay is a cyber security and big data analytics company with headquarters in Hod HaSharon, Israel, and offices in New York and Singapore.  The company provides a platform for detection of unknown threat and risks to protect critical infrastructure and financial services.  The platform is also used to uncover unknown opportunities based on big data.  The company utilizes patented mathematical algorithms developed by the company founders. migme Limited (formerly mig33) is a global digital media company focused on emerging markets.  The company is registered in Australia and listed on the Australian Securities Exchange (ASX:MIG) on 11 August 2014.  There is also a secondary listing on the Deutsche Borse (WKN: A117AB).  The company was formed in Perth, Australia in 2006 and commenced operations under the name mig33.  In 2014, it was rebranded migme (and underwent a product and corporate overhaul).  FIH Mobile, a handset unit of Taiwanese consumer electronics group Hon Hai Precision, took a 19.9% stake in the company in 2014.  Originally developed as a social chatting and gaming application for feature phones, migme has grown to become a mobile entertainment platform that services Southeast Asia, South Asia, the Middle East and Africa.  The company headquarters are in Singapore with offices in Malaysia, Indonesia, Taiwan, Hong Kong and Australia.  The company delivers social entertainment services through portfolio brands migme, LoveByte, alivenotdead and Sold. Commerce Square is a Class-A, high-rise office building complex in Center City Philadelphia, Pennsylvania, United States.  Commerce Square consists of One and Two Commerce Square, two identical 41-story office towers 565 ft high that surround a paved courtyard of 30000 sqft .  Architecturally, the granite-clad towers feature setbacks on the north and south sides of the building and are topped with a pair of stone diamonds with cutout squares in the center.  The towers were built as part an office-building boom Philadelphia was experiencing on West Market Street in the late 1980s.  Designed by IM Pei & Partners (now called Pei Cobb Freed & Partners), the towers were developed in a joint venture between Maguire Thomas Partners and IBM.  IBM also leased more than half of One Commerce Square for the company's Mid-Atlantic headquarters.  Construction of the first phase, which included One Commerce Square, the plaza, and retail space, began in 1985 and was completed in 1987.  The project's second phase, Two Commerce Square, did not begin until a lead tenant was secured for the building in 1990.  Consolidated Rail Corporation (Conrail) agreed to be Two Commerce Square's lead tenant and make the skyscraper its corporate headquarters after a two-year search for office space in the region.  Two Commerce Square ended the skyscraper construction boom of the 1980s when it was completed in 1992.  No other office skyscraper was built in Philadelphia until Brandywine Realty Trust (NYSE: BDN) built the Cira Centre in 2005.
Answer: Basel, Switzerland