Question: Reina Gossett is based in the most populous city in the United States, with an estimated 2016 population of what?
Context: Manchester is the largest city in the U.S. state of New Hampshire, the eleventh largest city in New England, and as of 2016 the largest city in northern New England, an area comprising the states of Maine, New Hampshire, and Vermont.  As of the 2010 census, the city had a population of 109,565, and its estimated 2016 population was 110,506.  It is located in Hillsborough County along the banks of the Merrimack River, which divides the city into eastern and western sections.  Manchester is near the northern end of the Northeast megalopolis.  It was first named by the merchant and inventor Samuel Blodget (after whom Samuel Blodget Park and Blodget Street in Manchester's North End are named).  Blodget's vision was to create a great industrial center similar to that of the original Manchester in England, which was the world's first industrialized city. Los Angeles ( ; Spanish for "The Angels"; ] ), officially the City of Los Angeles and often known by its initials L.A., is the cultural, financial, and commercial center of Southern California.  With a U.S. Census-estimated 2016 population of 3,976,322, it is the second most populous city in the United States (after New York City) and the most populous city in the state of California.  Located in a large coastal basin surrounded on three sides by mountains reaching up to and over 10000 ft , Los Angeles covers an area of about 469 sqmi .  The city is also the seat of Los Angeles County, the most populated county in the country.  Los Angeles is the center of the Los Angeles metropolitan area, with 13,131,431 residents, and is part of the larger designated Los Angeles-Long Beach combined statistical area (CSA), the second most populous in the nation with a 2015 estimated population of 18.7 million. Austin ( , ) is the capital of the U.S. state of Texas and the seat of Travis County, with portions extending into Hays and Williamson counties.  It is the 11th-most populous city in the United States and the 4th most populous city in Texas.  It is the fastest growing large city in the United States and the second most populous state capital in the U.S after Phoenix, Arizona.  As of the U.S. Census Bureau's July 1, 2016 estimate, Austin has a population of 947,890.  Located in Central Texas in the foothills of Texas Hill Country, the city is home to numerous lakes, rivers, and waterways including Lady Bird Lake, Barton Springs, McKinney Falls, the Colorado River, Lake Travis, and Lake Walter E. Long.  It is the cultural and economic center of the Austin–Round Rock metropolitan area, which had an estimated population of 2,056,405 as of July 1, 2016.  It is the most populous state capital in the U.S that isn't the most populous city in a state. The City of New York, often called New York City or simply New York, is the most populous city in the United States.  With an estimated 2016 population of 8,537,673 distributed over a land area of about 302.6 sqmi , New York City is also the most densely populated major city in the United States.  Located at the southern tip of the state of New York, the city is the center of the New York metropolitan area, one of the most populous urban agglomerations in the world.  A global power city, New York City exerts a significant impact upon commerce, finance, media and entertainment, art, fashion, research, technology, education, politics, and sports, its fast pace defining the term "New York minute".  Home to the headquarters of the United Nations, New York is an important center for international diplomacy and has been described as the cultural, financial, and media capital of the world. Reina Gossett is an activist, artist and writer based in New York City, currently the 2016-2018 Activist-in-Residence at Barnard Center for Research on Women.  She is most notable for her work in transgender activism and economic justice, through her work with the Sylvia Rivera Law Project and Queers for Economic Justice. Budapest (] ) is the capital and by far the most populous city of Hungary and one of the largest cities in the European Union.  With an estimated 2016 population of 1,759,407 distributed over a land area of about 525 km2 , Budapest is also one of the most densely populated major cities in the EU.  Budapest is both a city and county, and forms the centre of the Budapest metropolitan area, which has an area of 7,626 km2 and a population of 3,303,786, comprising 33 percent of the population of Hungary.  The Budapest metropolitan area had a GDP of $141.0 billion (€129.4 billion) in 2016, accounting for 49.6 percent of the GDP of Hungary.  GDP per capita in the city is $64,283, which means 148% of the EU average measured on purchasing power parity.  Thereby the city is among the top 100 GDP performing cities in the world Waco ( ) is a city which is the county seat of McLennan County, Texas, United States.  It is situated along the Brazos River and I-35, halfway between Dallas and Austin.  The city had a 2010 population of 124,805, making it the 22nd-most populous city in the state.  The US Census 2016 population estimate is 134,432 The Waco Metropolitan Statistical Area consists of McLennan and Falls Counties, which had a 2010 population of 234,906.  Falls County was added to the Waco MSA in 2013.  The US Census 2016 population estimate for the Waco MSA is 265,207. Sacramento ( ; ] ) is the capital city of the U.S. state of California and the seat of Sacramento County.  It is at the confluence of the Sacramento River and the American River in the northern portion of California's expansive Central Valley, known as the Sacramento Valley.  Its estimated 2016 population of 493,025 makes it the sixth-largest city in California, the fastest-growing big city in the state, and the 35th largest city in the United States.  Sacramento is the cultural and economic core of the Sacramento metropolitan area, which includes seven counties with a 2010 population of 2,414,783.  Its metropolitan area is the fourth largest in California after the Greater Los Angeles area, the San Francisco Bay Area, and the San Diego metropolitan area, and is the 27th largest in the United States.  In 2002, the Civil Rights Project at Harvard University conducted for "Time" magazine named Sacramento "America's Most Diverse City". Atlanta is the capital of and the most populous city in the U.S. state of Georgia, with an estimated 2016 population of 472,522.  Atlanta is the cultural and economic center of the Atlanta metropolitan area, home to 5,710,795 people and the ninth-largest metropolitan area in the United States.  Atlanta is the county seat of Fulton County, and a small portion of the city extends eastward into DeKalb County. Santa Maria is a city near the Southern California coast in Santa Barbara County.  It is approximately 160 mi northwest of Downtown Los Angeles.  Its estimated 2016 population was 106,290, making it the most populous city in the county and the Santa Maria-Santa Barbara, CA Metro Area.  The city is notable for its wine industry and Santa Maria-style barbecue.  "Sunset" magazine called Santa Maria "The West's Best BBQ Town".
Answer: 8,537,673