anurajms/meta_analysis huggingface dataset:
outcomes:
Surgery for idiopathic epiretinal membrane
1. Visual Acuity Testing 2. Visual Acuity Decreased
outcomes:
Lens extraction for chronic angle‐closure glaucoma
1. Gonioscopy With Evaluation 2. Visual Acuity Testing 3. Quality of Life 4. Intraocular Pressure Test 5. Visual Acuity Decreased 6. Adverse Event
outcomes:
Laser peripheral iridoplasty for chronic angle closure
1. Anterior Chamber Finding 2. Disease Progression 3. Quality of Life 4. Complication 5. Intraocular Pressure Test 6. Change Of Medication
outcomes:
Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma
1. Medication Dose Decreased 2. Repeat surgery 3. Endophthalmitis 4. Quality of Life 5. Intraocular Pressure Test 6. Haemorrhage 7. Visual Acuity Decreased 8. Raised Intraocular Pressure
outcomes:
Wavefront excimer laser refractive surgery for adults with refractive errors
1. Glare 2. Visual Acuity 3. Sudden Visual Loss 4. Halo vision 5. Refractive Errors
outcomes:
Visual cycle modulators versus placebo or observation for the prevention and treatment of geographic atrophy due to age‐related macular degeneration
1. Best-corrected visual acuity 2. Visual Acuity Testing 3. Visual Acuity Decreased 4. Adverse Event
outcomes:
Corneal collagen cross‐linking for bacterial infectious keratitis
1. Postoperative Complication 2. Corneal Finding 3. Visual Acuity Testing 4. Corneal Epithelial Defect 5. Healing
outcomes:
Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related macular degeneration
1. Increased Vision 2. Visual Acuity Testing 3. Endophthalmitis 4. Quality of Life 5. Retinal Thickening
outcomes:
Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond laser for LASIK in adults with myopia or myopic astigmatism
1. Corneal Subepithelial Haze 2. Diffuse Lamellar Keratitis 3. Dry Eyes 4. Visual Acuity Testing 5. Epithelial Ingrowth
outcomes:
Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction
1. Fluorescein Staining Of Cornea 2. Decreased Tear Film Break-up Time 3. Adverse Event 4. Meibomian Gland Finding 5. Clinical Improvement
outcomes:
Ab interno trabecular bypass surgery with Schlemm´s canal microstent (Hydrus) for open angle glaucoma
1. Repeat surgery 2. Endophthalmitis 3. Quality of Life 4. Intraocular Pressure Test 5. Haemorrhage 6. Visual Acuity Decreased 7. Raised Intraocular Pressure
outcomes:
Low vision rehabilitation for better quality of life in visually impaired adults
1. Quality of Life 2. Depression 3. Difficulty Reading
outcomes:
Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification
1. Visual Acuity Testing 2. Correction Of Astigmatism 3. Complication Of Intraocular Lens Implant 4. Patient Satisfaction
outcomes:
Pars plana vitrectomy combined with scleral buckle versus pars plana vitrectomy for giant retinal tear
1. Retinal Detachment 2. Reattachment Of Choroid And Retina
outcomes:
Topical cyclosporine A therapy for dry eye syndrome
1. Schirmer's Test 2. Fluorescein Staining Of Eye 3. Tear film stability 4. Rose Bengal Staining Of Eye 5. Decreased Tear Film Break-up Time 6. Adverse Event 7. Clinical Improvement
outcomes:
Conventional occlusion versus pharmacologic penalization for amblyopia
1. Stereotests - Tno 2. Visual Acuity Testing 3. Quality of Life 4. Patient compliance 5. Adverse Event
outcomes:
Intrastromal corneal ring segments for treating keratoconus
1. Visual Acuity Testing
outcomes:
Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma
1. Intraocular Pressure Decreased 2. Visual Acuity Testing 3. Intraocular Pressure Test 4. Adverse Event 5. Visual Acuity Decreased
outcomes:
Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma
1. Medication Dose Decreased 2. Repeat surgery 3. Endophthalmitis 4. Haemorrhage 5. Raised Intraocular Pressure 6. Visual Acuity Decreased
outcomes:
Cyclodestructive procedures for refractory glaucoma
1. Pain 2. Visual Acuity Testing 3. Quality of Life 4. Intraocular Pressure Test 5. Adverse Event 6. Antiglaucoma Preparations And Miotics
outcomes:
Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments
1. Treatment Success 2. Visual Acuity Testing 3. Quality of Life 4. Reattachment Of Choroid And Retina 5. Recent Total Retinal Detachment 6. Adverse Event
outcomes:
Endoscopic cyclophotocoagulation (ECP) for open angle glaucoma and primary angle closure
1. Medication Dose Decreased 2. Endophthalmitis 3. Haemorrhage 4. Raised Intraocular Pressure 5. Visual Acuity Decreased
outcomes:
Routine preoperative medical testing for cataract surgery
1. Healthcare costs 2. Quality of Life 3. Clinical Management Plan Review 4. Canceled Operative Procedure 5. Adverse Event
outcomes:
Anti‐tumour necrosis factor biological therapies for the treatment of uveitic macular oedema (UMO) for non‐infectious uveitis
1. Visual Acuity Testing 2. Visual Acuity Decreased
outcomes:
Subconjunctival draining minimally‐invasive glaucoma devices for medically uncontrolled glaucoma
1. Endophthalmitis 2. Intraocular Pressure Test 3. Haemorrhage 4. Visual Acuity Decreased 5. Raised Intraocular Pressure
outcomes:
Descemet's membrane endothelial keratoplasty (DMEK) versus Descemet's stripping automated endothelial keratoplasty (DSAEK) for corneal endothelial failure
1. Corneal Endothelium Finding 2. Corneal Graft Rejection 3. Corneal Graft Failure 4. Visual Acuity Testing 5. Corneal Graft Disorder
outcomes:
Blue‐light filtering intraocular lenses (IOLs) for protecting macular health
1. Loss Of Visual Contrast Sensitivity 2. Age-related Macular Degeneration 3. Finding Of Color Vision 4. Visual Acuity Testing 5. Adverse Event
outcomes:
Reading aids for adults with low vision
1. Using aids in daily life 2. Quality of Life 3. Adverse Event 4. Difficulty Reading
outcomes:
Optical correction of refractive error for preventing and treating eye symptoms in computer users
1. Dizziness 2. Headache 3. Asthenopia 4. Visual Analog Scale 5. Nausea 6. Upset stomach 7. Health-Related Quality of Life 8. Patient-Reported Outcome
outcomes:
Adjustable versus non‐adjustable sutures for strabismus
1. Costs and Cost Analysis 2. Ocular Muscle Balance Normal 3. Adverse Event 4. Patient Satisfaction
outcomes:
Interventions to increase attendance for diabetic retinopathy screening
1. Costs and Cost Analysis 2. Reinforcement Of Adherence To Treatment Regimen
outcomes:
Anti‐vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity
1. Severe Visual Impairment 2. Cataract 3. Retinal Detachment 4. Disease Recurrence 5. Retinopathy Of Prematurity 6. Retinal Haemorrhage 7. Blindness 8. Corneal Transplant 9. Death 10. Corneal Opacity 11. Refractive Errors
outcomes:
Surgical interventions for vertical strabismus in superior oblique palsy
1. Hypertropia 2. Follow-up Examination Normal
outcomes:
Interventions to improve access to cataract surgical services and their impact on equity in low‐ and middle‐income countries
1. Cataract 2. Health Services Utilization 3. Blindness 4. Adverse Event
outcomes:
Ocriplasmin for symptomatic vitreomacular adhesion
1. Eyes and vision 2. Macular hole 3. Vitreomacular Adhesion 4. Vitrectomy 5. Posterior Vitreous Detachment 6. Adverse Event
outcomes:
Different‐sized incisions for phacoemulsification in age‐related cataract
1. Endothelial Cell Morphometry 2. Corneal Edema 3. Corneal Thickening 4. Astigmatism
outcomes:
Aqueous shunts for glaucoma
1. Finding Of Visual Field 2. Visual Acuity Testing 3. Quality of Life 4. Intraocular Pressure Test 5. Adverse Event 6. Glaucoma surgery
outcomes:
Probing for congenital nasolacrimal duct obstruction
1. Disease Condition Determination, Cured
outcomes:
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery
1. Corneal Edema 2. Anterior Chamber Flare 3. Best-corrected Distance Visual Acuity Decreased 4. Cystoid Macular Edema 5. Adverse Event 6. Intraocular Lens Associated Postoperative Inflammation
outcomes:
Nd:YAG laser vitreolysis versus pars plana vitrectomy for vitreous floaters
1. Eyes and vision
outcomes:
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions
1. Corneal Abrasion 2. Wound healed 3. Adverse Drug Interaction
outcomes:
Autologous serum eye drops for dry eye
1. Fluorescein Staining 2. Rose Bengal Staining Of Eye 3. Decreased Tear Film Break-up Time
outcomes:
N‐acetylcarnosine (NAC) drops for age‐related cataract
1. Cataract Finding
outcomes:
Endonasal versus external dacryocystorhinostomy for nasolacrimal duct obstruction
1. Postoperative Hemorrhage 2. Intraoperative Hemorrhage 3. Lacrimal Drainage - Freely Patent 4. Wound Infection
outcomes:
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty
1. Intraocular Pressure Test
outcomes:
Topical medication instillation techniques for glaucoma
1. Intraocular Pressure Test
outcomes:
Surgery for cataracts in people with age‐related macular degeneration
1. Choroidal Retinal Neovascularization 2. Visual Acuity Testing 3. Quality of Life
outcomes:
Laser‐assisted subepithelial keratectomy (LASEK) versus laser‐assisted in‐situ keratomileusis (LASIK) for correcting myopia
1. Corneal Subepithelial Haze 2. Visual Acuity Testing
outcomes:
Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery
1. Visual Acuity Testing 2. Endophthalmitis
outcomes:
Non‐surgical interventions for acute internal hordeolum
1. Disease Condition Determination, Cured
outcomes:
Anti‐vascular endothelial growth factor for choroidal neovascularisation in people with pathological myopia
1. Choroidal Retinal Neovascularization 2. Serious Adverse Event 3. Quality of Life 4. Adverse Event
outcomes:
Multifocal versus monofocal intraocular lenses after cataract extraction
1. Wears Glasses 2. Glare 3. Visual Halos 4. Visual Acuity Testing 5. Quality of Life
outcomes:
Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery
1. Postoperative Complication 2. Disease Recurrence 3. Duration Of Surgery
outcomes:
Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts
1. Corneal Graft Rejection 2. Herpes Simplex Keratitis
outcomes:
Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients
1. Pain 2. Uveitis 3. Disseminated Herpes Zoster 4. Dendritic Ulcer 5. Edema Of Eyelid 6. Vomit: Bilious
outcomes:
Integrated versus non‐integrated orbital implants for treating anophthalmic sockets
1. Treatment Failure 2. Normal Ocular Motility 3. Follow-up Examination Normal 4. Adverse Event
outcomes:
Prophylactic non‐steroidal anti‐inflammatory drugs for the prevention of macular oedema after cataract surgery
1. Visual Acuity Testing 2. Quality of Life 3. Macular Edema 4. Retinal Thickening
outcomes:
Statins for age‐related macular degeneration
1. Age-related Macular Degeneration 2. Visual Acuity Testing 3. Death 4. Muscle Pain 5. Inflammatory Disease Of Liver
outcomes:
Patching for corneal abrasion
1. Pain 2. Quality of Life 3. Wound Healing 4. Adverse Event
outcomes:
Antibiotics versus no treatment for toxoplasma retinochoroiditis
1. Disease Recurrence 2. Visual Acuity Testing 3. Inflammation 4. Adverse Event
outcomes:
Over the counter (OTC) artificial tear drops for dry eye syndrome
1. Dry Eyes
outcomes:
Laser‐assisted subepithelial keratectomy (LASEK) versus photorefractive keratectomy (PRK) for correction of myopia
1. Corneal Subepithelial Haze 2. Visual Acuity Testing
outcomes:
Peripheral iridotomy for pigmentary glaucoma
1. Visual Field Defect 2. Intraocular Pressure Test
outcomes:
Conjunctival autograft for pterygium
1. Recurrent Pterygium 2. Visual Acuity Testing 3. Quality of Life
outcomes:
Aflibercept for neovascular age‐related macular degeneration
1. Visual Acuity Testing
outcomes:
Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis
1. Keratitis 2. Iridocyclitis 3. Visual Acuity Testing 4. Visual Field Defect 5. Onchocerca Chorioretinitis 6. Punctate Keratitis 7. Optic Atrophy 8. Hemorrhagic Diarrhea 9. Onchocerciasis
outcomes:
Anti‐vascular endothelial growth factor for control of wound healing in glaucoma surgery
1. Disease Condition Determination, Cured 2. Wound Leak Of Eye 3. Hypotony Of Eye 4. Endophthalmitis 5. Intraocular Pressure Test 6. Shallow Anterior Chamber Of Eye
outcomes:
Interventions for dissociated vertical deviation
1. Hypotropia 2. Dissociated Vertical Deviation
outcomes:
Interventions for trachoma trichiasis
1. Disease Recurrence
outcomes:
Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery
1. Treatment Failure 2. Hypotony Of Eye 3. Visual Acuity Testing 4. Endophthalmitis 5. Intraocular Pressure Test 6. Choroidal Detachment
outcomes:
Day care versus in‐patient surgery for age‐related cataract
1. Postoperative Complication 2. Costs and Cost Analysis 3. Visual Acuity Testing
outcomes:
Laser treatment of drusen to prevent progression to advanced age‐related macular degeneration
1. Exudative age-related macular degeneration 2. Loss Of Visual Contrast Sensitivity 3. Nonexudative Age-related Macular Degeneration 4. Visual Acuity Testing 5. Difficulty Reading 6. Macular Drusen
outcomes:
Intravitreal steroids versus observation for macular edema secondary to central retinal vein occlusion
1. Glaucoma 2. Cataract 3. Visual Acuity Testing 4. Endophthalmitis 5. Raised Intraocular Pressure
outcomes:
Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery
1. Pain 2. Administration Of Anesthesia 3. Progress Satisfactory 4. Intraoperative Pain 5. Patient Satisfaction
outcomes:
Immunosuppressants for the prophylaxis of corneal graft rejection after penetrating keratoplasty
1. Primary Failure Of Corneal Graft After Penetrating Keratoplasty
outcomes:
Corticosteroids for treating optic neuritis
1. Visual Acuity Testing 2. Visual Field Defect 3. Impairment Of Visual Contrast Sensitivity
outcomes:
Interventions for idiopathic intracranial hypertension
1. Headache 2. Papilledema 3. Visual Acuity Testing 4. Csf Pressure: Normal
outcomes:
Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma
1. Surgical complication 2. Treatment Failure 3. Intraocular Pressure Test 4. Management of drug regimen
outcomes:
Assistive technology for children and young people with low vision
1. Difficulty Reading
outcomes:
Macular grid laser photocoagulation for branch retinal vein occlusion
1. Visual Acuity Testing
outcomes:
Medical interventions for fungal keratitis
1. Disease Condition Determination, Cured 2. Visual Acuity Testing 3. Quality of Life 4. Perforation Of Cornea 5. Patient compliance
outcomes:
Surgery for nonarteritic anterior ischemic optic neuropathy
1. Visual Acuity Testing
outcomes:
Optical reading aids for children and young people with low vision
1. Difficulty Reading
outcomes:
Medical interventions for acanthamoeba keratitis
1. Conjunctival Foreign Body 2. Corneal Edema 3. Disease Condition Determination, Cured 4. Pain 5. Corneal Inflammatory Stromal Infiltration 6. Photophobia 7. Corneal Epithelial Defect 8. Scleritis 9. Blurring Of Visual Image 10. Drug toxicity
outcomes:
Face washing promotion for preventing active trachoma
1. Trachoma, Active Stage 2. Unclean
outcomes:
Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis
1. Disease Condition Determination, Cured 2. Keratitis 3. Wound Healing
outcomes:
Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment
1. Retinal Detachment
outcomes:
Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
1. Visual Acuity Testing
outcomes:
D‐Penicillamine for preventing retinopathy of prematurity in preterm infants
1. Retinopathy Of Prematurity
outcomes:
Vitamin D for the treatment of inflammatory bowel disease
1. Full Mayo Score 2. Disease Progression 3. Harvey And Bradshaw Index 4. Quality of Life 5. Crohn Disease Activity Index
outcomes:
Fibrin‐based haemostatic agents for reducing blood loss in adult liver resection
1. Serious Adverse Event 2. Treatment Success 3. Death 4. Health-Related Quality of Life
outcomes:
Prostaglandins for adult liver transplanted recipients
1. Serious Adverse Event 2. Quality of Life 3. Liver Disease Quality of Life Instrument
outcomes:
Expanded polytetrafluoroethylene (ePTFE)‐covered stents versus bare stents for transjugular intrahepatic portosystemic shunt in people with liver cirrhosis
1. Stent migration 2. Sepsis 3. Haemobilia 4. Haemorrhage
outcomes:
Rifaximin for prevention and treatment of hepatic encephalopathy in people with cirrhosis
1. Ammonia 2. Serious Adverse Event 3. Hepatic Encephalopathy 4. Length Of Stay 5. Death 6. Adverse Event 7. Number Connection Test 8. Health-Related Quality of Life
outcomes:
Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery
1. Serious Adverse Event 2. Costs and Cost Analysis 3. Pancreatic Fistula 4. Quality of Life 5. Death 6. Length Of Stay
outcomes:
Granulocyte colony‐stimulating factor with or without stem or progenitor cell or growth factors infusion for people with compensated or decompensated advanced chronic liver disease
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Exercise interventions for adults after liver transplantation
1. Serious Adverse Event 2. Death 3. Health-Related Quality of Life
outcomes:
Remote care through telehealth for people with inflammatory bowel disease
1. Crohn's Disease 2. Relapse 3. Ulcerative Colitis Activity Index 4. Disease Activity Score 5. Ulcerative Colitis 6. Quality of Life 7. Crohn Disease Activity Index 8. Inflammatory Bowel Disease
outcomes:
Patient education interventions for the management of inflammatory bowel disease
1. Relapse 2. Quality of Life 3. Inflammatory Bowel Disease 4. Adverse Event
outcomes:
Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage
1. Serious Adverse Event 2. Death
outcomes:
Interventions to improve sanitation for preventing diarrhoea
1. Diarrhea
outcomes:
Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia
1. Dysphagia 2. Acid Reflux
outcomes:
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins
1. Relapse 2. Typhoid Fever 3. Paratyphoid Fever 4. Failure
outcomes:
Electromagnetic‐guided versus endoscopic‐guided postpyloric placement of nasoenteral feeding tubes
1. Aspiration Pneumonitis 2. Nasoenteral Tube 3. Healthcare costs 4. Adverse Event
outcomes:
Certolizumab pegol for maintenance of medically induced remission in Crohn’s disease
1. Serious Adverse Event 2. Remission 3. Crohn Disease Activity Index 4. Adverse Event 5. Therapeutic Response 6. Health-Related Quality of Life
outcomes:
Physical activity for treatment of irritable bowel syndrome
1. Adequate Relief Measure 2. IBS Symptom Questionnaire 3. Functional Bowel Disorder Severity Index 4. GI Symptom Rating Scale 5. Irritable Bowel Syndrome Severity Scoring System 6. Clinical Improvement
outcomes:
Antibiotics for uncomplicated diverticulitis
1. Diverticulitis 2. Surgery
outcomes:
Stem cell transplantation for induction of remission in medically refractory Crohn’s disease
1. Serious Adverse Event 2. Remission 3. Perianal Fistula 4. Crohn Disease Activity Index 5. Adverse Event 6. Clinical Improvement
outcomes:
Tacrolimus (FK506) for induction of remission in corticosteroid‐refractory ulcerative colitis
1. Serious Adverse Event 2. Ulcerative Colitis 3. Proctocolectomy 4. Adverse Event 5. Rescue Medication 6. Clinical Improvement
outcomes:
Guidewire‐assisted cannulation of the common bile duct for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis
1. Post-endoscopic retrograde cholangiopancreatography pancreatitis
outcomes:
Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding
1. Endoscopic hemostasis therapy 2. Surgery 3. Death 4. Rebleeding 5. Stigmata
outcomes:
Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Mesh fixation techniques in primary ventral or incisional hernia repair
1. Recurrent Hernia Of Anterior Abdominal Wall 2. Pain 3. Recurrent Ventral Incisional Hernia 4. Health-Related Quality of Life
outcomes:
Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta‐analysis
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta‐analysis
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Risk of postoperative infectious complications from medical therapies in inflammatory bowel disease
1. Postoperative Infection 2. Complication 3. Wound Dehiscence 4. Incision Site Infection
outcomes:
Portosystemic shunts versus endoscopic intervention with or without medical treatment for prevention of rebleeding in people with cirrhosis
1. All Cause Mortality 2. Hepatic Encephalopathy 3. Death 4. Rebleeding 5. Health-Related Quality of Life
outcomes:
Interventions for preventing postpartum constipation
1. Defecation Straining 2. Pain 3. Quality of Life 4. Loose Stools 5. Stomach cramps 6. Diarrhoea 7. Constipation 8. Defecation
outcomes:
Adalimumab for maintenance of remission in Crohn's disease
1. Treatment Failure
outcomes:
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair
1. Wound Infection
outcomes:
Nasogastric versus nasojejunal tube feeding for severe acute pancreatitis
1. Infection 2. Single organ failure 3. Surgery 4. Treatment Success 5. Complication 6. Death
outcomes:
Anti‐IL‐12/23p40 antibodies for maintenance of remission in Crohn's disease
1. Serious Adverse Event 2. Treatment Failure 3. Withdrawal Due To Adverse Events 4. Adverse Event
outcomes:
Adalimumab for induction of remission in Crohn's disease
1. Serious Adverse Event 2. Treatment Failure 3. Quality of Life 4. Withdrawal Due To Adverse Events 5. Adverse Event 6. Therapeutic Response
outcomes:
Band ligation versus beta‐blockers for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
1. Upper Gastrointestinal Hemorrhage 2. All Cause Mortality 3. Serious Adverse Event 4. Health-Related Quality of Life
outcomes:
Certolizumab pegol for induction of remission in Crohn's disease
1. Serious Adverse Event 2. Crohn's Disease In Remission 3. Therapeutic Response
outcomes:
Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation
1. Stomal Prolapse 2. Stenosis 3. Skin Irritation 4. Parastomal Hernia 5. Intestinal Obstruction
outcomes:
Adjuvant therapy with antidepressants for the management of inflammatory bowel disease
1. Pain 2. Quality of Life 3. Depression 4. Anxiety 5. Adverse Event
outcomes:
Glucocorticosteroids for people with alcoholic hepatitis
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
N‐acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication
1. Gastrointestinal findings 2. Combinations For Eradication Of Helicobacter Pylori 3. Allergies
outcomes:
Antibiotics for induction and maintenance of remission in Crohn's disease
1. Serious Adverse Event 2. Crohn's Disease In Remission 3. Adverse Event
outcomes:
Acetyl‐L‐carnitine for patients with hepatic encephalopathy
1. All Cause Mortality 2. Serious Adverse Event 3. Quality of Life 4. Fatigue 5. Length Of Stay 6. Adverse Event
outcomes:
Cannabis for the treatment of ulcerative colitis
1. Relapse 2. Ulcerative Colitis In Remission 3. Serious Adverse Event 4. C-reactive Protein level 5. Quality of Life 6. Withdrawal Due To Adverse Events 7. Adverse Event 8. Therapeutic Response
outcomes:
Surgical portosystemic shunts versus transjugular intrahepatic portosystemic shunt for variceal haemorrhage in people with cirrhosis
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Swallowing therapy for dysphagia in acute and subacute stroke
1. Disability 2. Modified Rankin Scale 3. Death 4. Length Of Stay 5. Dysphagia 6. Physical Functional Dependency 7. Finding Related To Ability To Swallow 8. Barthel Index
outcomes:
Carvedilol versus traditional, non‐selective beta‐blockers for adults with cirrhosis and gastroesophageal varices
1. Treatment Failure
outcomes:
Prokinetics for functional dyspepsia
1. Clinical Improvement
outcomes:
Modifying the consistency of food and fluids for swallowing difficulties in dementia
1. Aspiration 2. Quality of Life 3. Respiratory finding 4. Non-compliant Behavior 5. Adverse Event 6. Nutritional Finding
outcomes:
Mesh versus non‐mesh for inguinal and femoral hernia repair
1. Surgical complication 2. Seroma 3. Urinary Retention 4. Testicular Finding 5. Postoperative Wound Abscess 6. Time-to-Event 7. Wound Dehiscence 8. Activities of Daily Living 9. Postoperative Pain 10. Recurrent Inguinal Hernia 11. Visceral Decompression Injury 12. Duration Of Surgery 13. Hematoma 14. Death 15. Duration Of Hospital Stay 16. Neurovascular Injury 17. Wound Infection
outcomes:
Epidural analgesia versus patient‐controlled intravenous analgesia for pain following intra‐abdominal surgery in adults
1. Analgesic Technique 2. Venous Thrombosis 3. Visual Analog Scale 4. Low Blood Pressure 5. Pruritus 6. Sedation 7. Decreased Respiratory Function 8. Adverse Event 9. All Cause Mortality 10. Pain 11. Hypoxemia 12. Nausea And Vomiting 13. Treatment Failure
outcomes:
Surgical portosystemic shunts versus devascularisation procedures for prevention of variceal rebleeding in people with hepatosplenic schistosomiasis
1. All Cause Mortality 2. Serious Adverse Event 3. Quality of Life 4. Brain disorder 5. Rebleeding 6. Ascites
outcomes:
Prosthetic mesh placement for the prevention of parastomal herniation
1. Infection 2. Procedure On Rectum 3. Procedure On Colon 4. Duration Of Surgery 5. Device Related Infection 6. Quality of Life 7. Duration Of Hospital Stay 8. Hospitalization 9. Parastomal Hernia 10. Patient-Reported Outcome
outcomes:
Glucocorticosteroids for infants with biliary atresia following Kasai portoenterostomy
1. All Cause Mortality 2. Serious Adverse Event 3. Health-Related Quality of Life
outcomes:
Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease
1. Relapse 2. Serious Adverse Event 3. Adverse Event
outcomes:
Interventions for paracetamol (acetaminophen) overdose
1. Liver transplant 2. Death
outcomes:
Feed thickener for infants up to six months of age with gastro‐oesophageal reflux
1. Posseting 2. Normal Gastric Acidity 3. Respiratory Symptom 4. Reflux 5. Bradycardia 6. Sleep Disturbed 7. Vomiting 8. Gastroesophageal Reflux Disease 9. Regurgitation 10. Feeling Irritable 11. Diarrhoea 12. Failure To Thrive 13. Hematemesis
outcomes:
Laparoscopic versus open resection for sigmoid diverticulitis
1. Gastric Anastomotic Stricture 2. Surgical complication 3. Hospitalization 4. Postoperative Pain 5. Intraoperative Hemorrhage 6. Morbidity Index 7. Postoperative Diet 8. Diverticulitis Of Sigmoid Colon 9. Surgery 10. Quality of Life 11. Death 12. Complication 13. Intestinal Obstruction
outcomes:
Proton pump inhibitors for functional dyspepsia
1. Nonulcer Dyspepsia
outcomes:
Closure methods of the appendix stump for complications during laparoscopic appendectomy
1. Laparoscopic Surgery 2. Postoperative Hemorrhage 3. Postoperative Complication 4. Surgical Site Infection 5. Appendectomy 6. Postoperative Wound Infection-deep 7. Hospitalization 8. Soiling 9. Purulent Peritonitis 10. Paralytic Ileus 11. Intraoperative Hemorrhage 12. Intraoperative Complications 13. Rupture Of Appendix 14. Complication 15. Injury Of Internal Organ
outcomes:
Mesalamine (5‐ASA) for the prevention of recurrent diverticulitis
1. Disease Recurrence 2. Diverticulitis 3. Adverse Event
outcomes:
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs
1. Viral Hepatitis C
outcomes:
Direct‐acting antivirals for chronic hepatitis C
1. Viral Hepatitis C 2. Quality of Life 3. Adverse Event
outcomes:
Ursodeoxycholic acid for cystic fibrosis‐related liver disease
1. Portal Hypertension 2. Weight change 3. Hepatocellular Liver Damage 4. Finding Of Biliary Tract 5. Liver transplant 6. Death 7. Liver Finding 8. Nutritional Finding
outcomes:
Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy
1. All Cause Mortality 2. Serious Adverse Event 3. Hepatic Encephalopathy
outcomes:
Terlipressin versus placebo or no intervention for people with cirrhosis and hepatorenal syndrome
1. Serious Adverse Event 2. Hepatorenal Syndrome 3. Death
outcomes:
Management for intussusception in children
1. Postoperative Complication 2. Disease Recurrence 3. Treatment Success 4. Intestinal Perforation 5. Ileocecal Intussusception 6. Excision Of Intestinal Structure
outcomes:
Oral calorie supplements for cystic fibrosis
1. Body Mass Index 2. Forced Expiratory Volume 1 3. Dietary Fat Intake 4. Inadequate Dietary Intake Of Protein 5. Inadequate Dietary Caloric Intake 6. Body weight 7. Height and growth measurements 8. Adverse Event
outcomes:
Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients
1. Peritoneal Dialysis Catheter Exit Site Infection 2. Removal Of Peritoneal Dialysis Catheter 3. Peritoneal Dialysis Catheter Tunnel Infection 4. Replacement Of Peritoneal Dialysis Catheter 5. Peritonitis
outcomes:
Maintenance immunosuppression for adults undergoing liver transplantation: a network meta‐analysis
1. Graft loss 2. Death 3. Adverse Event 4. Health-Related Quality of Life
outcomes:
Deprescribing versus continuation of chronic proton pump inhibitor use in adults
1. Endoscopy Finding 2. Costs and Cost Analysis 3. Proton Pump Inhibitors 4. Patient Satisfaction Score 5. Symptom control therapy
outcomes:
Antibiotic treatment for Clostridium difficile‐associated diarrhoea in adults
1. Adverse Drug Reaction 2. Clostridium Difficile Infection 3. Death 4. Diarrhoea
outcomes:
Hepatitis B immunoglobulin during pregnancy for prevention of mother‐to‐child transmission of hepatitis B virus
1. Serious Adverse Event 2. Neonatal Death 3. Maternal Death 4. Hepatitis B
outcomes:
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty
1. Infection 2. Activities of Daily Living 3. Postoperative Wound Infection-superficial 4. Recurrent Inguinal Hernia 5. Duration Of Surgery 6. Hematoma 7. Chronic Pain
outcomes:
Polymer‐based oral rehydration solution for treating acute watery diarrhoea
1. Hyponatremia 2. Vomiting 3. Hypokalemia 4. Diarrhoea
outcomes:
Anti‐IL‐12/23p40 antibodies for induction of remission in Crohn's disease
1. Withdrawn From Research Study 2. Crohn's Disease 3. Crohn's Disease In Remission 4. Treatment Failure 5. Adverse Event
outcomes:
Methods to decrease blood loss during liver resection: a network meta‐analysis
1. Quality of Life 2. Death 3. Adverse Event
outcomes:
Heated insufflation with or without humidification for laparoscopic abdominal surgery
1. Core Temperature 2. Pain 3. Pain Scale 4. Duration Of Surgery 5. Morphine 6. Hospitalization 7. Time-to-Event 8. Clinical Improvement
outcomes:
Oral 5‐aminosalicylic acid for maintenance of medically‐induced remission in Crohn's disease
1. Withdrawn From Research Study 2. Crohn's Disease 3. Serious Adverse Event 4. Treatment Failure 5. Adverse Event
outcomes:
Internal dressings for healing perianal abscess cavities
1. Wound Pain 2. Wound Healing
outcomes:
Osmotic and stimulant laxatives for the management of childhood constipation
1. Faecal incontinence 2. Serious Adverse Event 3. Frequency Of Defecation 4. Drug Therapy 5. Fecal Disimpaction 6. Adverse Event
outcomes:
Anti‐tuberculous therapy for maintenance of remission in Crohn's disease
1. Relapse 2. Adverse Event
outcomes:
Epidural local anaesthetics versus opioid‐based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery
1. Pain 2. Vomiting 3. Postoperative Ileus 4. Visual Analog Scale 5. Length Of Stay 6. Stool Finding 7. Anastomotic leak 8. Finding Of Flatus
outcomes:
Aminosalicylates for induction of remission or response in Crohn's disease
1. Withdrawn From Research Study 2. Crohn's Disease 3. Crohn's Disease In Remission 4. Adverse Event
outcomes:
Sequential versus standard triple first‐line therapy for Helicobacter pylori eradication
1. Bacterial Resistance 2. Adverse Event
outcomes:
Booster dose vaccination for preventing hepatitis B
1. Serious Adverse Event 2. Hepatocellular carcinoma 3. Death 4. Liver cirrhosis 5. Hepatitis B
outcomes:
Fasting for haemostasis in children with gastrointestinal bleeding
1. Continued bleeding 2. Haemorrhage
outcomes:
Pancreatic duct guidewire placement for biliary cannulation for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis
1. Perforation 2. Pancreatitis 3. Cholangitis 4. Death 5. Cannulation 6. Haemorrhage 7. Endoscopic Retrograde Cholangiopancreatography 8. Post-ercp Acute Pancreatitis
outcomes:
Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis
1. Serious Adverse Event 2. Hepatic Encephalopathy 3. Death
outcomes:
Eradication therapy for peptic ulcer disease in Helicobacter pylori‐positive people
1. Duodenal Ulcer 2. Gastric Ulcer 3. Peptic Ulcer
outcomes:
Interventions for necrotising pancreatitis
1. Healthcare costs 2. Serious Adverse Event 3. Drug Therapy 4. Death 5. Length Of Stay 6. Intensive Care 7. Health-Related Quality of Life
outcomes:
Perioperative dexmedetomidine for acute pain after abdominal surgery in adults
1. Postoperative Pain 2. Analgesic Effect 3. Opioids 4. Mobility function 5. Visual Analog Scale 6. Sedated 7. Stool Finding 8. Ramsay Sedation Scale 9. Postoperative Nausea And Vomiting 10. Rescue Medication 11. Time-to-Event 12. Passing Flatus
outcomes:
Interventions for dysphagia in long‐term, progressive muscle disease
1. Body weight
outcomes:
Glutamine for induction of remission in Crohn's disease
1. Crohn's Disease In Remission
outcomes:
Periodontal therapy as adjunctive treatment for gastric Helicobacter pylori infection
1. Helicobacter Pylori Gastritis
outcomes:
Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis
1. All Cause Mortality 2. Serious Adverse Event 3. Pancreatic Insufficiency 4. Quality of Life 5. Length Of Stay 6. Death 7. Health-Related Quality of Life
outcomes:
Pregabalin for decreasing pancreatic pain in chronic pancreatitis
1. Pain 2. Serious Adverse Event 3. Analgesics 4. Health-Related Quality of Life
outcomes:
Enhanced recovery protocols for major upper gastrointestinal, liver and pancreatic surgery
1. Serious Adverse Event 2. Costs and Cost Analysis 3. Death 4. Duration Of Hospital Stay 5. Readmission 6. Adverse Event 7. Health-Related Quality of Life
outcomes:
Antibiotic prophylaxis for surgical site infection in people undergoing liver transplantation
1. Surgical Site Infection 2. Quality of Life 3. Death 4. Adverse Event
outcomes:
Etrolizumab for induction of remission in ulcerative colitis
1. Serious Adverse Event 2. Ulcerative Colitis In Remission 3. Treatment Failure 4. Adverse Event
outcomes:
Surgery for complete (full‐thickness) rectal prolapse in adults
1. Faecal incontinence 2. Postoperative Complication 3. Defecation Straining 4. Disease Recurrence 5. Euroqol Five Dimension Questionnaire 6. Quality of Life 7. Complete Rectal Prolapse 8. Altered Bowel Function 9. Patient-Reported Outcome
outcomes:
Treatment for dysphagia (swallowing difficulties) in hereditary ataxia
1. Assessment Using Assessment Scale 2. Healthcare costs 3. Lower Respiratory Tract Infection 4. Swallowing Finding 5. Individual General Health Examination 6. Short Form Health Survey - 36 7. Aspiration 8. Caregiver Role Strain 9. Evaluation Of Oral And Pharyngeal Swallowing Function 10. Health Care Utilization 11. Lifestyle Issues
outcomes:
Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults
1. Reflux 2. Serious Adverse Event 3. Quality of Life 4. Dysphagia 5. Adverse Event 6. Heartburn 7. Health-Related Quality of Life
outcomes:
Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease
1. Crohn's Disease In Remission 2. Serious Adverse Event 3. Withdrawal Due To Adverse Events 4. Adverse Event
outcomes:
Oral budesonide for induction of remission in ulcerative colitis
1. Withdrawn From Research Study 2. Serious Adverse Event 3. Ulcerative Colitis In Remission 4. Plasma Cortisol 5. Withdrawal Due To Adverse Events 6. Adverse Event 7. Clinical Improvement
outcomes:
Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery
1. Tracheal Intubation Event 2. Death 3. Duration Of Hospital Stay 4. Intensive Care
outcomes:
Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery
1. Postoperative Complication 2. All Cause Mortality 3. Postoperative Atelectasis 4. Duration Of Hospital Stay 5. Adverse Event 6. Mechanical ventilation 7. Postoperative Pneumonia
outcomes:
Interventions for heartburn in pregnancy
1. Fetal Growth Restriction 2. Adverse Drug Reaction 3. Fetal anomalies 4. Insomnia 5. Muscle Cramp 6. Premature Labor 7. Diarrhoea 8. Low Birth Weight Infant 9. Miscarriage 10. Constipation 11. Heartburn 12. Allergies
outcomes:
Type I interferons for induction of remission in ulcerative colitis
1. Serious Adverse Event 2. Ulcerative Colitis In Remission 3. Withdrawal Due To Adverse Events 4. Clinical Improvement
outcomes:
Methotrexate for maintenance of remission in ulcerative colitis
1. Relapse 2. Ulcerative Colitis In Remission
outcomes:
Unfractionated or low‐molecular weight heparin for induction of remission in ulcerative colitis
1. Ulcerative Colitis In Remission 2. Clinical Improvement
outcomes:
Post‐pyloric versus gastric tube feeding for preventing pneumonia and improving nutritional outcomes in critically ill adults
1. Pneumonia 2. Complication of device insertion 3. Nutrient Intake 4. Maintenance Of Device 5. Enteral nutrition 6. Death 7. Complication 8. Nutritional Finding 9. Mechanical ventilation 10. Time-to-Event
outcomes:
Plugs for containing faecal incontinence
1. Faecal incontinence 2. Urgent Desire For Stool 3. Bowel Movement Diary 4. Patient-Reported Outcome
outcomes:
Antifibrinolytic amino acids for upper gastrointestinal bleeding in people with acute or chronic liver disease
1. Upper Gastrointestinal Haemorrhage 2. Death 3. Adverse Event
outcomes:
Budesonide for induction of remission in Crohn's disease
1. Withdrawn From Research Study 2. Crohn's Disease In Remission 3. Disease Progression 4. Withdrawal Due To Adverse Events 5. Clinical Improvement
outcomes:
Water infusion versus air insufflation for colonoscopy
1. Adenoma 2. Cecal Intubation Rate
outcomes:
Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in people with portal hypertension
1. All Cause Mortality 2. Serious Adverse Event 3. Recurrent Hemorrhage 4. Septicemia 5. Death 6. Pulmonary Embolism
outcomes:
Enteral nutrition formulations for acute pancreatitis
1. All Cause Mortality 2. Serious Adverse Event 3. Systemic Inflammatory Response Syndrome 4. Multiple Organ Dysfunction Syndrome 5. Adverse Event
outcomes:
Endoscopic or surgical intervention for painful obstructive chronic pancreatitis
1. Exocrine Pancreatic Insufficiency 2. Quality of Life 3. Pancreatic Insufficiency 4. Death 5. Pain Relief
outcomes:
Treatment for cryoglobulinemic and non‐cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection
1. INCAT Sensory Sum Score 2. Neurological Assessment 3. Neuropathy Impairment Scale 4. Utah Early Neuropathy Scale 5. Clinical Improvement
outcomes:
Tranexamic acid for upper gastrointestinal bleeding
1. Transfusion 2. Surgery 3. Death 4. Haemorrhage 5. Adverse Event 6. Thromboembolic Event
outcomes:
Hepatitis B vaccination during pregnancy for preventing infant infection
1. Hepatitis Viral Infections
outcomes:
Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease
1. Disease exacerbation
outcomes:
Non‐nutritive sucking for gastro‐oesophageal reflux disease in preterm and low birth weight infants
1. Gastroesophageal Reflux Disease
outcomes:
Epinephrine injection versus epinephrine injection and a second endoscopic method in high‐risk bleeding ulcers
1. Surgery 2. Death 3. Haemorrhage 4. Adverse Event
outcomes:
Interventions for treating postpartum constipation
1. Defecation Straining 2. Painful Defecation 3. Stool Finding 4. Constipation 5. Patient-Reported Outcome
outcomes:
Budesonide for maintenance of remission in Crohn's disease
1. Crohn's Disease In Remission
outcomes:
Vedolizumab for induction and maintenance of remission in ulcerative colitis
1. Relapse 2. Inadequate Clinical Response To Medication 3. Serious Adverse Event 4. Remission 5. Adverse Event
outcomes:
Methotrexate for induction of remission in refractory Crohn's disease
1. Treatment Withdrawal 2. Serious Adverse Event 3. Treatment Failure 4. Withdrawal Due To Adverse Events 5. Adverse Event
outcomes:
Antimicrobial drugs for treating cholera
1. Stool 2. Diarrhoea
outcomes:
Antimicrobial prophylaxis for colorectal surgery
1. Surgical Wound Infection
outcomes:
Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders
1. Caregiver satisfaction 2. Aspiration 3. Laryngeal penetration 4. Adverse Event 5. Patient Satisfaction
outcomes:
Dopamine agents for hepatic encephalopathy
1. All Cause Mortality 2. Serious Adverse Event 3. Hepatic Encephalopathy 4. Morbidity
outcomes:
Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
1. All Cause Mortality 2. Serious Adverse Event 3. Quality of Life 4. Duration Of Hospital Stay
outcomes:
Abdominal lift for laparoscopic cholecystectomy
1. Cholecystectomy 2. Serious Adverse Event 3. Quality of Life 4. Death
outcomes:
Opioids for acute pancreatitis pain
1. Analgesia 2. All Cause Mortality 3. Pain 4. Vomiting 5. Pancreatitis 6. Complication 7. Nausea 8. Sedation 9. Sleepiness
outcomes:
Laparoscopic repair for perforated peptic ulcer disease
1. Surgical Site Infection 2. Abdominal abscess 3. Dehiscence Of Internal Surgical Wound 4. Postoperative Ileus
outcomes:
Open Mesh versus non‐Mesh for groin hernia repair
1. Hernia 2. Pain 3. Operation time 4. Seroma 5. Hematoma 6. Complication 7. Length Of Stay 8. Death 9. Surgical approach 10. Daily living activities 11. Numbness 12. Wound Infection
outcomes:
Antioxidant supplementation for sickle cell disease
1. Quality of Life 2. Severe Pain 3. Complication 4. Hospitalization 5. Sickle Cell Crisis 6. Adverse Event 7. Hemoglobin concentration
outcomes:
Nebuliser systems for drug delivery in cystic fibrosis
1. Intervention duration 2. Quality of Life
outcomes:
Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis
1. Quality of Life 2. Hospitalization 3. Exercise Capacity 4. Lung function test 5. Adverse Event 6. Patient compliance
outcomes:
Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis
1. Cystic Fibrosis Pulmonary Exacerbation 2. Self-management 3. Physical Activity Assessment
outcomes:
Interventions for the long‐term prevention of hereditary angioedema attacks
1. Hereditary angioedema 2. Serious Adverse Event
outcomes:
Strategies for screening for familial hypercholesterolaemia in primary care and other community settings
1. Adverse Event 2. Familial Hypercholesterolemia
outcomes:
Embolisation for pulmonary arteriovenous malformation
1. All Cause Mortality 2. Venous Occlusion
outcomes:
Long‐acting inhaled bronchodilators for cystic fibrosis
1. Forced Expiratory Volume 1 2. Cystic Fibrosis Pulmonary Exacerbation 3. Quality of Life 4. Lung function test 5. Adverse Event 6. Patient-Reported Outcome
outcomes:
Enzyme replacement therapy for infantile‐onset Pompe disease
1. Ventilation Finding 2. Complication Of Infusion 3. Cardiac Function Testing 4. Motor Development - Child 5. Quality of Life 6. Adverse Event 7. Time-to-Event 8. Survival
outcomes:
Beta‐blockers for preventing aortic dissection in Marfan syndrome
1. Blood pressure measurement 2. Treatment Withdrawal 3. Aortic Root Finding 4. Death 5. Adverse Event
outcomes:
Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease
1. Low Cardiac Output Syndrome 2. Death 3. Hospitalization 4. Intensive Care 5. Adverse Event 6. Mechanical ventilation
outcomes:
Non‐invasive ventilation for cystic fibrosis
1. Quality of Life 2. Death 3. Breathing-related Sleep Disorder
outcomes:
Non‐surgical interventions for treating heavy menstrual bleeding (menorrhagia) in women with bleeding disorders
1. Observer-Reported Outcome 2. Finding Of Quantity Of Menstrual Blood Loss 3. Adverse Event 4. Patient Satisfaction 5. Patient-Reported Outcome
outcomes:
Pneumococcal vaccines for cystic fibrosis
1. Cystic Fibrosis Pulmonary Exacerbation 2. Quality of Life 3. Hospitalization 4. Pneumococcal Infectious Disease 5. Antibiotic Therapy
outcomes:
Intravenous alpha‐1 antitrypsin augmentation therapy for treating patients with alpha‐1 antitrypsin deficiency and lung disease
1. Death 2. Adverse Event
outcomes:
Enzyme replacement therapy for Anderson‐Fabry disease
1. Mcgill Pain Chart Questionnaire 2. Transient Cerebrovascular Events 3. All Cause Mortality 4. Pain 5. Cardiovascular Event 6. Renal Function Monitoring 7. Ceramides 8. Acroparesthesia 9. Pain Crisis
outcomes:
Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis
1. Death 2. Hospitalization 3. Respiratory Syncytial Virus Infection
outcomes:
Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis‐related lung disease
1. Forced Expiratory Volume 1 2. Forced Vital Capacity 3. Cystic Fibrosis Pulmonary Exacerbation 4. Lung function test 5. Survival 6. Antibiotic Therapy
outcomes:
Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis
1. Forced Expiratory Volume 1 2. Forced Vital Capacity 3. Influenza 4. Respiratory Function 5. Hospitalization 6. Symptom control therapy
outcomes:
Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome)
1. General Finding Of Height 2. 6-minute Walk Test 3. Body weight
outcomes:
Anti‐inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis‐related arthritis
1. Painful Swelling Of Joint 2. Arthritis By Pattern Of Joint Involvement 3. Limitation Of Joint Movement 4. Quality of Life 5. Functional ability 6. Swollen Joints
outcomes:
Home versus hospital intravenous antibiotic therapy for cystic fibrosis
1. Forced Expiratory Volume 1 2. Forced Vital Capacity 3. Infectious Disease Of Lung 4. Lung function test 5. Clinical Improvement
outcomes:
Ascorbic acid for the treatment of Charcot‐Marie‐Tooth disease
1. Disability 2. Assessment Using Nine Hole Peg Test 3. Serious Adverse Event 4. Impairment 5. Timed 10 Meter Walk 6. Neuropathy Impairment Scale 7. Inflammatory Neuropathy Cause and Treatment Disability Scale 8. Medical Research Council (MRC) Sum Score 9. Rankin Disability Scale
outcomes:
Oral steroids for long‐term use in cystic fibrosis
1. Forced Expiratory Volume 1 2. Forced Vital Capacity 3. Hospitalization 4. Lung function test 5. Antibiotic Therapy