anurajms/meta_analysis huggingface dataset:
Provide selection criteria that should be included in the study
Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis
Randomised and quasi‐randomised studies.
Provide selection criteria that should be included in the study
Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis‐related lung disease
Randomised controlled studies comparing topical CFTR gene delivery to the lung, using either viral or non‐viral delivery systems, with placebo or an alternative delivery system in people with confirmed cystic fibrosis.
Provide selection criteria that should be included in the study
Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis
Randomised controlled trials and quasi‐randomised controlled trials comparing neuraminidase inhibitors with placebo or other antiviral drugs.
Provide selection criteria that should be included in the study
Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome)
Randomised and quasi‐randomised controlled trials of enzyme replacement therapy with idursulfase compared to no intervention, placebo or other options (e.g. behavioral strategies, transplantation).
Provide selection criteria that should be included in the study
Anti‐inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis‐related arthritis
Randomised controlled studies which compared the efficacy and safety of anti‐inflammatory and analgesic agents (e.g. non‐steroidal anti‐inflammatory agents, systemic corticosteroids, intra‐articular corticosteroids) with each other, with no treatment or with placebo for CFA and HPO.
Provide selection criteria that should be included in the study
Home versus hospital intravenous antibiotic therapy for cystic fibrosis
Randomized and quasi‐randomized controlled studies of intravenous antibiotic treatment for adults and children with cystic fibrosis at home compared to in hospital.
Provide selection criteria that should be included in the study
Ascorbic acid for the treatment of Charcot‐Marie‐Tooth disease
We included RCTs and quasi‐RCTs of any ascorbic acid treatment for people with CMT. Where a study aimed to evaluate the treatment of general neuromuscular symptoms of people with peripheral neuropathy including CMT, we included the study if we were able to identify the effect of treatment in the CMT group. We did not include observational studies or case reports of ascorbic acid treatment in people with CMT.
Provide selection criteria that should be included in the study
Oral steroids for long‐term use in cystic fibrosis
Randomised trials comparing oral corticosteroids given for more than 30 days with placebo or no additional therapy in people with CF.
Provide selection criteria that should be included in the study
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis
Randomised trials (published or unpublished) comparing Pseudomonas aeruginosa vaccines (oral, parenteral or intranasal) with control vaccines or no intervention in cystic fibrosis.
Provide selection criteria that should be included in the study
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Randomised controlled trials and the first treatment cycle of cross‐over studies comparing intravenous antibiotics (given alone or in an antibiotic combination) with placebo, inhaled or oral antibiotics for people with cystic fibrosis experiencing a pulmonary exacerbation.
Provide selection criteria that should be included in the study
Prophylactic milrinone for the prevention of low cardiac output syndrome and mortality in children undergoing surgery for congenital heart disease
Only randomised controlled trials were selected for analysis. We considered studies with newborn infants, infants, toddlers, and children up to 12 years of age.
Provide selection criteria that should be included in the study
Surgical interventions for treating pectus excavatum
We considered randomized or quasi‐randomized controlled trials that compared traditional surgery with minimally invasive surgery for treating pectus excavatum.
Provide selection criteria that should be included in the study
Sodium channel blockers for cystic fibrosis
Published or unpublished randomised controlled trials (RCTs) or quasi‐randomised controlled trials of sodium channel blockers compared to placebo or another sodium channel blocker or the same sodium channel blocker at a different dosing regimen.
Provide selection criteria that should be included in the study
Vaccines for preventing influenza in people with cystic fibrosis
All randomised and quasi‐randomised trials (published or unpublished) comparing any influenza vaccine with a placebo or with another type of influenza vaccine.
Provide selection criteria that should be included in the study
Interventions for promoting physical activity in people with cystic fibrosis
All randomised and quasi‐randomised controlled studies which investigated strategies designed to promote increased participation in daily physical activity for individuals with cystic fibrosis.
Provide selection criteria that should be included in the study
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis
Randomized and quasi‐randomized controlled trials comparing nebulized or oral thiol derivatives to placebo or another thiol derivative in people with cystic fibrosis.
Provide selection criteria that should be included in the study
Single‐incision sling operations for urinary incontinence in women
We included randomised or quasi‐randomised controlled trials in women with stress (or stress‐predominant mixed) urinary incontinence in which at least one, but not all, trial arms included a single‐incision sling.
Provide selection criteria that should be included in the study
Surgical approach to hysterectomy for benign gynaecological disease
We included randomised controlled trials (RCTs) in which clinical outcomes were compared between one surgical approach to hysterectomy and another.
Provide selection criteria that should be included in the study
Combined oral contraceptive pill for primary dysmenorrhoea
We included randomised controlled trials (RCTs) comparing all combined OCPs with other combined OCPs, placebo, or management with non‐steroidal anti‐inflammatory drugs (NSAIDs). Participants had to have primary dysmenorrhoea, diagnosed by ruling out pelvic pathology through pelvic examination or ultrasound.
Provide selection criteria that should be included in the study
Surgery for women with apical vaginal prolapse
We included randomised controlled trials (RCTs).
Provide selection criteria that should be included in the study
Statins for women with polycystic ovary syndrome not actively trying to conceive
We included randomised controlled trials (RCTs) that evaluated the effects of statin therapy in women with PCOS not actively trying to conceive. Eligible comparisons were statin versus placebo or no treatment, statin plus another agent versus the other agent alone, and statin versus another agent. We performed statistical analysis using Review Manager 5, and we assessed the certainty of the evidence using GRADE methods.
Provide selection criteria that should be included in the study
Gonadotropin‐releasing hormone analogues for endometriosis
We included randomised controlled trials (RCTs) which compared GnRHas with other hormonal treatment options, including analgesics, danazol, intra‐uterine progestogens, oral or injectable progestogens, gestrinone and also GnRHas compared with no treatment or placebo. Trials comparing GnRHas versus GnRHas in conjunction with add‐back therapy (hormonal or non‐hormonal) or calcium‐regulation agents were also included in this review.
Provide selection criteria that should be included in the study
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults
We included randomised or quasi‐randomised trials in adults with overactive bladder syndrome that compared an anticholinergic drug alone with placebo treatment.
Provide selection criteria that should be included in the study
Immediate versus delayed postpartum insertion of contraceptive implant and IUD for contraception
We sought randomized controlled trials (RCTs) that compared immediate postpartum versus delayed insertion of contraceptive implant and IUDs for contraception.
Provide selection criteria that should be included in the study
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency
We included randomised controlled trials (RCTs) investigating the effect of various hormonal preparations on the uterine development of women diagnosed with POI.
Provide selection criteria that should be included in the study
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use
We included RCTs in any language that tested strategies for treatment or prevention of heavy menstrual bleeding or pain associated with IUD (Cu IUD, LNG IUD or other IUD) use. The comparison could be no intervention, placebo or another active intervention.
Provide selection criteria that should be included in the study
Medical methods for first trimester abortion
We considered randomised controlled trials (RCTs) that compared different medical methods for abortion before the 12th week of gestation. The primary outcome is failure to achieve complete abortion. Secondary outcomes are mortality, surgical evacuation, ongoing pregnancy at follow‐up, time until passing of conceptus, blood transfusion, side effects and women's dissatisfaction with the method.
Provide selection criteria that should be included in the study
Immediate versus delayed postabortal insertion of contraceptive implant
We sought randomized controlled trials (RCTs) comparing immediate versus delayed insertion of contraceptive implant for contraception following abortion.
Provide selection criteria that should be included in the study
Treatment for recurrent vulvovaginal candidiasis (thrush)
We considered all published and unpublished randomised controlled trials evaluating RVVC treatments for at least six months, in women with four or more symptomatic episodes of vulvovaginal candidiasis in the past year. We excluded women with immunosuppressive disorders or taking immunosuppressant medication. We included women with diabetes mellitus and pregnant women.Diagnosis of RVVC must have been confirmed by presence of symptoms and a positive culture and/or microscopy. We included all drug and non‐drug therapies and partner treatment, assessing the following primary outcomes:• number of clinical recurrences per participant per year (recurrence defined as clinical signs and positive culture/microscopy);
• proportion of participants with at least one clinical recurrence during the treatment and follow‐up period; and
• adverse events.
Provide selection criteria that should be included in the study
Surgical interventions for the management of chronic pelvic pain in women
RCTs with women who had CPPS. The review authors were prepared to consider studies of any surgical intervention used for the management of CPPS. Outcome measures were pain rating scales, adverse events, psychological outcomes, quality of life (QoL) measures and requirement for analgesia.
Provide selection criteria that should be included in the study
Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery
We included randomised controlled trials (RCTs) comparing women undergoing surgical treatment of endometriosis with uterine preservation who were assigned to LNG‐IUD insertion, versus control conditions including expectant management, post‐operative insertion of placebo (inert intrauterine device), or other medical treatment such as gonadotrophin‐releasing hormone agonist (GnRH‐a) drugs.
Provide selection criteria that should be included in the study
Ultrasound‐guided transvaginal ovarian needle drilling for clomiphene‐resistant polycystic ovarian syndrome in subfertile women
We planned to include randomised controlled trials comparing UTND to laparoscopic ovarian drilling, and UTND combined with gonadotropins to gonadotropins, in women of reproductive age with clomiphene‐resistant PCOS and infertility.
Provide selection criteria that should be included in the study
Pentoxifylline for the treatment of endometriosis‐associated pain and infertility  
We included randomised controlled trials (RCTs) comparing pentoxifylline with placebo or no treatment, other medical treatment, or surgery in women with endometriosis. The primary outcomes were live birth rate and overall pain (as measured by a visual analogue scale (VAS) of pain, other validated scales, or dichotomous outcomes) per woman randomised. Secondary outcomes included clinical pregnancy rate, miscarriage rate, rate of recurrence, and adverse events resulting from the pentoxifylline intervention.
Provide selection criteria that should be included in the study
Medical abortion offered in pharmacy versus clinic‐based settings
We identified studies that compared women receiving the same regimen of medical abortion or post‐abortion care in either a clinic or pharmacy setting. Studies published in any language employing the following designs were included: randomized trials and non‐randomized studies including a comparative group.
Provide selection criteria that should be included in the study
Selective oestrogen receptor modulators (SERMs) for endometriosis
We included randomised controlled trials (RCTs) comparing selective oestrogen receptor modulators (SERMs) with placebo, no treatment, other medical treatment, or surgery for endometriosis.
Provide selection criteria that should be included in the study
Dopamine agonists for preventing ovarian hyperstimulation syndrome
We considered RCTs for inclusion that compared dopamine agonists with placebo/no intervention or another intervention for preventing OHSS in ART. Primary outcome measures were incidence of moderate or severe OHSS and live birth rate. Secondary outcomes were rates of clinical pregnancy, multiple pregnancy, miscarriage, and adverse events.
Provide selection criteria that should be included in the study
Metformin treatment before and during IVF or ICSI in women with polycystic ovary syndrome
Types of studies: randomised controlled trials (RCTs) comparing metformin treatment with placebo or no treatment in women with PCOS who underwent IVF or ICSI treatment.Types of participants: women of reproductive age with anovulation due to PCOS with or without co‐existing infertility factors.Types of interventions: metformin administered before and during IVF or ICSI treatment.Primary outcome measures: live birth rate, incidence of ovarian hyperstimulation syndrome.
Provide selection criteria that should be included in the study
Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical therapy)
All identified published or unpublished randomised controlled trials (RCTs) assessing the effect of progestogens or progestogen‐releasing intrauterine systems in treating premenopausal women with uterine fibroids.
Provide selection criteria that should be included in the study
Pessaries (mechanical devices) for managing pelvic organ prolapse in women
We included randomised and quasi‐randomised controlled trials which included a pessary for pelvic organ prolapse in at least one arm of the study.
Provide selection criteria that should be included in the study
Pre‐ and postsurgical medical therapy for endometriosis surgery
We included randomized controlled trials (RCTs) which compared medical therapies for hormonal suppression before, after, or before and after, therapeutic surgery for endometriosis.
Provide selection criteria that should be included in the study
Laparoscopic surgery for endometriosis
We selected randomised controlled trials (RCTs) that compared the effectiveness and safety of laparoscopic surgery with any other laparoscopic or robotic intervention, holistic or medical treatment, or diagnostic laparoscopy only.
Provide selection criteria that should be included in the study
Surgical treatment for tubal disease in women due to undergo in vitro fertilisation
Randomised controlled trials (RCTs) comparing surgical treatment versus no surgical treatment, or comparing surgical interventions head‐to‐head, in women with tubal disease prior to undergoing IVF.
Provide selection criteria that should be included in the study
Tubal flushing for subfertility
Randomised controlled trials (RCTs) comparing tubal flushing with OSCM, WSCM with each other or with no treatment, in women with subfertility.
Provide selection criteria that should be included in the study
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia
Randomised controlled trials (RCTs) and cross‐over trials of women with a histological diagnosis of endometrial hyperplasia with or without atypia comparing LNG‐IUS with non‐intrauterine progestogens, placebo, surgery or no treatment.
Provide selection criteria that should be included in the study
Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis (thrush)
We included randomised controlled trials published in any language comparing at least one oral anti‐fungal with one intra‐vaginal anti‐fungal in women (aged 16 years or over) with a mycological diagnosis (positive culture, microscopy for yeast, or both) of uncomplicated vulvovaginal candidiasis. We excluded trials if they solely involved participants who were HIV positive, immunocompromised, pregnant, breast feeding or diabetic.
Provide selection criteria that should be included in the study
Interventions for non‐tubal ectopic pregnancy
We included randomized controlled trials (RCTs) published in all languages that examined the effects and safety of surgery, medical treatment, and expectant management of non‐tubal ectopic pregnancy.
Provide selection criteria that should be included in the study
Progestogen‐releasing intrauterine systems for heavy menstrual bleeding
We included randomised controlled trials (RCTs) in women of reproductive age treated with LNG‐IUS devices versus no treatment, placebo, or other medical or surgical therapy for heavy menstrual bleeding.
Provide selection criteria that should be included in the study
In‐bag manual versus uncontained power morcellation for laparoscopic myomectomy
We included all randomised controlled trials comparing in‐bag extracorporeal manual morcellation versus intracorporeal uncontained power morcellation during laparoscopic myomectomy in premenopausal women.
Provide selection criteria that should be included in the study
Self‐administered versus provider‐administered medical abortion
We included randomized controlled trials (RCTs) and prospective cohort studies with a concurrent comparison group, using study designs that compared medical abortion by self‐administered versus provider‐administered methods.
Provide selection criteria that should be included in the study
Traditional suburethral sling operations for urinary incontinence in women
Randomised or quasi‐randomised trials that assessed traditional suburethral slings for treating stress or mixed urinary incontinence.
Provide selection criteria that should be included in the study
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome
We included randomised controlled trials of metformin compared with placebo, no treatment, or in combination with or compared with CC, letrozole and LOD for women with PCOS subfertility.
Provide selection criteria that should be included in the study
Laparoscopic colposuspension for urinary incontinence in women
Randomised controlled trials of women with urinary incontinence that included laparoscopic surgery in at least one arm.
Provide selection criteria that should be included in the study
Long‐term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosis
Randomised controlled trials (RCTs) involving women with surgically diagnosed endometriosis that compared use of any type of GnRH agonist for at least three months before an IVF/ICSI protocol to no pretreatment or other pretreatment modalities, specifically use of long‐term continuous COC (minimum of 6 weeks) or surgical excision of endometrioma within six months prior to standard IVF/ICSI. The primary outcomes were live birth rate and complication rate per woman randomised.
Provide selection criteria that should be included in the study
Exercise for dysmenorrhoea
We included studies if they randomised women with moderate‐to‐severe primary dysmenorrhoea to receive exercise versus no treatment, attention control, non‐steroidal anti‐inflammatory drugs (NSAIDs) or the oral contraceptive pill. Cross‐over studies and cluster‐randomised trials were not eligible for inclusion.
Provide selection criteria that should be included in the study
Non‐steroidal anti‐inflammatory drugs for heavy menstrual bleeding
The inclusion criteria were randomised comparisons of individual NSAIDs or combined with other medical therapy with each other, placebo or other medical treatments in women with regular heavy periods measured either objectively or subjectively and with no pathological or iatrogenic (treatment‐induced) causes for their HMB.
Provide selection criteria that should be included in the study
Interventions for treating recurrent stress urinary incontinence after failed minimally invasive synthetic midurethral tape surgery in women
We included randomised and quasi‐randomised controlled trials in women who had recurrent stress urinary incontinence after previous minimally invasive midurethral tape surgery. We included conservative, pharmacological and surgical treatments.
Provide selection criteria that should be included in the study
Cyclical progestogens for heavy menstrual bleeding
Randomized controlled trials (RCTs) comparing different treatments for HMB that included cyclical oral progestogens were eligible.
Provide selection criteria that should be included in the study
Antibiotic therapy for adults with neurosyphilis
We included randomised clinical trials that included men and women, regardless of age, with definitive diagnoses of neurosyphilis, including HIV‐seropositive patients. We compared any antibiotic regime (concentration, dose, frequency, duration), compared to any other antibiotic regime for the treatment for neurosyphilis in adults.
Provide selection criteria that should be included in the study
Robot‐assisted surgery in gynaecology
Randomised controlled trials (RCTs) comparing RAS versus CLS or open surgery in women requiring surgery for gynaecological disease.
Provide selection criteria that should be included in the study
Lifestyle changes in women with polycystic ovary syndrome
Randomised controlled trials (RCTs) comparing lifestyle treatment (diet, exercise, behavioural or combined treatments) to minimal or no treatment in women with PCOS.
Provide selection criteria that should be included in the study
Combined hormonal contraceptives for heavy menstrual bleeding
We included randomised controlled trials (RCTs) of the use of COCP or CVR compared with no treatment, placebo, or other medical therapies for women with HMB and regular menstrual cycles.
Provide selection criteria that should be included in the study
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures
Randomised controlled trials (RCTs) of interventions used during or immediately after gynaecological laparoscopy to reduce the incidence or severity of STP.
Provide selection criteria that should be included in the study
Endometrial resection and ablation techniques for heavy menstrual bleeding
Randomised controlled trials (RCTs) comparing different endometrial ablation or resection techniques for women reporting HMB without known uterine pathology, other than fibroids outside the uterine cavity and smaller than 3 centimetres, were eligible. Outcomes included improvement in HMB and in quality of life, patient satisfaction, operative outcomes, complications, and the need for further surgery, including hysterectomy.
Provide selection criteria that should be included in the study
Gonadotrophins for ovulation induction in women with polycystic ovary syndrome
All randomised controlled trials reporting data on clinical outcomes in women with PCOS who did not ovulate or conceive on clomiphene citrate, and undergoing ovulation induction with urinary‐derived gonadotrophins, including urofollitropin (uFSH) in purified FSH (FSH‐P) or highly purified FSH (FSH‐HP) form, human menopausal gonadotropin (HMG) and highly purified human menopausal gonadotrophin (HP‐HMG), or recombinant FSH (rFSH), or continuing clomiphene citrate. We included trials reporting on ovulation induction followed by intercourse or intrauterine insemination. We excluded studies that described co‐treatment with clomiphene citrate, metformin, luteinizing hormone, or letrozole.
Provide selection criteria that should be included in the study
Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women
Randomised or quasi‐randomised controlled trials in women with SUI, UUI or MUI (based on symptoms, signs or urodynamics). One arm of the trial included PFMT. Another arm was a no treatment, placebo, sham or other inactive control treatment arm.
Provide selection criteria that should be included in the study
Surgery for women with pelvic organ prolapse with or without stress urinary incontinence
Randomised controlled trials (RCTs) including surgical operations for POP with or without continence procedures in continent or incontinent women. Our primary outcome was subjective postoperative SUI. Secondary outcomes included recurrent POP on examination, overactive bladder (OAB) symptoms, and voiding dysfunction.
Provide selection criteria that should be included in the study
Acupuncture and acupressure for premenstrual syndrome
We included studies if they randomised women with PMS and associated disorders (PMDD and late luteal phase dysphoric disorder/LPDD) to receive acupuncture or acupressure versus sham, usual care/waiting‐list control or pharmaceutical interventions mentioned by the International Society for Premenstrual Disorders (ISPMD). If acupuncture or acupressure were combined with another therapy, these studies were also included where the additional therapy was the same in both groups. Cross‐over studies were eligible for inclusion, but only data from the first phase could be used.
Provide selection criteria that should be included in the study
Oral contraceptives for pain associated with endometriosis
We included randomised controlled trials (RCT) of the use of COCPs in the treatment of women of reproductive age with symptoms ascribed to the diagnosis of endometriosis that had been made visually at a surgical procedure.
Provide selection criteria that should be included in the study
Surgery for women with posterior compartment prolapse
We included randomised controlled trials (RCTs) comparing different types of surgery for posterior vaginal wall prolapse.
Provide selection criteria that should be included in the study
Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
We included randomised controlled trials of insulin‐sensitising drugs compared with placebo, no treatment, or an ovulation‐induction agent for women with oligo and anovulatory PCOS.
Provide selection criteria that should be included in the study
Preoperative medical therapy before surgery for uterine fibroids
We included randomised comparisons of medical therapy versus placebo, no treatment, or other medical therapy before surgery, myomectomy, hysterectomy or endometrial resection, for uterine fibroids.
Provide selection criteria that should be included in the study
Anterior vaginal repair for urinary incontinence in women
Randomised or quasi‐randomised trials that included anterior vaginal repair for the treatment of urinary incontinence.
Provide selection criteria that should be included in the study
Mid‐urethral sling operations for stress urinary incontinence in women
Randomised or quasi‐randomised controlled trials amongst women with SUI, USI or MUI, in which both trial arms involve a MUS operation.
Provide selection criteria that should be included in the study
Open retropubic colposuspension for urinary incontinence in women
Randomised or quasi‐randomised controlled trials in women with symptoms or urodynamic diagnoses of stress or mixed urinary incontinence that included open retropubic colposuspension surgery in at least one trial group.
Provide selection criteria that should be included in the study
Bladder neck needle suspension for urinary incontinence in women
Randomised or quasi‐randomised trials that included needle suspension for the treatment of urinary incontinence.
Provide selection criteria that should be included in the study
Progesterone receptor modulators for endometriosis
We included randomised controlled trials (RCTs) published in all languages that examined effects of PRMs for treatment of symptomatic endometriosis.
Provide selection criteria that should be included in the study
Antibiotic prophylaxis for elective hysterectomy
All randomised controlled trials (RCTs) comparing use of antibiotics versus placebo or other antibiotics as prophylaxis in women undergoing elective hysterectomy.
Provide selection criteria that should be included in the study
Selective progesterone receptor modulators (SPRMs) for uterine fibroids
Included studies were randomised controlled trials (RCTs) of premenopausal women with fibroids who were treated for at least three months with a SPRM.
Provide selection criteria that should be included in the study
Washout policies in long‐term indwelling urinary catheterisation in adults
All randomised and quasi‐randomised trials comparing catheter washout policies (e.g. washout versus no washout, different washout solutions, frequency, duration, volume, concentration, method of administration) in adults (aged 16 years and above) in any setting (i.e. hospital, nursing/residential home, community) with an indwelling urethral or suprapubic catheter for more than 28 days.
Provide selection criteria that should be included in the study
Surgery for tubal infertility
We considered only randomised controlled trials to be eligible for inclusion, with livebirth rate per participant as the primary outcome of interest.
Provide selection criteria that should be included in the study
Nonsteroidal anti‐inflammatory drugs for pain in women with endometriosis
We included all randomised controlled trials (RCTs) describing use of NSAIDs for management of pain associated with endometriosis in women of all ages.
Provide selection criteria that should be included in the study
Long‐term hormone therapy for perimenopausal and postmenopausal women
We included randomised double‐blinded studies of HT versus placebo, taken for at least 1 year by perimenopausal or postmenopausal women. HT included oestrogens, with or without progestogens, via the oral, transdermal, subcutaneous or intranasal route.
Provide selection criteria that should be included in the study
Surgery for women with anterior compartment prolapse
Randomised controlled trials (RCTs) that examined surgical operations for anterior compartment prolapse.
Provide selection criteria that should be included in the study
Interventions for preventing and treating incontinence‐associated dermatitis in adults
We selected randomised controlled trials (RCTs) and quasi‐RCTs, performed in any healthcare setting, with included participants over 18 years of age, with or without IAD. We included trials comparing the (cost) effectiveness of topical skin care products such as skin cleansers, moisturisers, and skin protectants of different compositions and skin care procedures aiming to prevent and treat IAD.
Provide selection criteria that should be included in the study
Short‐term and long‐term effects of tibolone in postmenopausal women
We included randomised controlled trials (RCTs) comparing tibolone versus placebo, oestrogens and/or combined hormone therapy (HT) in postmenopausal and perimenopausal women.
Provide selection criteria that should be included in the study
Antibiotic treatment for the sexual partners of women with bacterial vaginosis
Randomized controlled trials (RCTs) that compared the concurrent use of any antibiotic treatment with placebo, no intervention or any other intervention by the sexual partners of women treated for BV.
Provide selection criteria that should be included in the study
Techniques for the interruption of tubal patency for female sterilisation
All randomized controlled trials (RCTs) comparing different techniques for tubal sterilisation, irrespective of the route of fallopian tube access or the method of anaesthesia.
Provide selection criteria that should be included in the study
Bioidentical hormones for women with vasomotor symptoms
Randomised controlled trials (RCTs) comparing bioidentical hormone therapy (BHT) versus placebo or non‐bioidentical hormones.
Provide selection criteria that should be included in the study
Policies for replacing long‐term indwelling urinary catheters in adults
All randomised controlled trials investigating policies for replacing long‐term indwelling urinary catheters in adults were included.
Provide selection criteria that should be included in the study
Antibiotics for treating septic abortion
We considered for inclusion randomised controlled trials (RCTs) and non‐RCTs that compared antibiotic(s) to another antibiotic(s), irrespective of route of administration, dosage, and duration as well as studies comparing antibiotics alone with antibiotics in combination with other interventions such as dilation and curettage (D&C).
Provide selection criteria that should be included in the study
Chinese herbal medicine for menopausal symptoms
Randomised controlled trials (RCTs) comparing the effectiveness of CHM with placebo, HT, pharmaceutical drugs, acupuncture, or another CHM formula in women over 18 years of age, and suffering from menopausal symptoms.
Provide selection criteria that should be included in the study
Tricyclic and related drugs for nocturnal enuresis in children
We included all randomised and quasi‐randomised trials comparing a tricyclic or related drug with another intervention for treating enuresis. We also included combination therapies that included tricyclics. We excluded trials for treating daytime wetting.
Provide selection criteria that should be included in the study
Trocar types in laparoscopy
RCTs that compared rates of trocar‐related complications and postoperative pain for different trocar types used in people undergoing laparoscopy. The primary outcomes were major trocar‐related complications, such as mortality, conversion due to any trocar‐related adverse event, visceral injury, vascular injury and other injuries that required intensive care unit (ICU) management or a subsequent surgical, endoscopic or radiological intervention. Secondary outcomes were minor trocar‐related complications and postoperative pain. We excluded trials that studied non‐conventional laparoscopic incisions.
Provide selection criteria that should be included in the study
Urethral (indwelling or intermittent) or suprapubic routes for short‐term catheterisation in hospitalised adults
We included all randomised and quasi‐randomised trials comparing different routes of catheterisation for short‐term use in hospitalised adults.
Provide selection criteria that should be included in the study
Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women
We included randomised or quasi‐randomised trials with two or more arms, of women with clinical or urodynamic evidence of stress urinary incontinence, urgency urinary incontinence or mixed urinary incontinence. One arm of the trial included PFMT added to another active treatment; the other arm included the same active treatment alone.
Provide selection criteria that should be included in the study
Hormonal and intrauterine methods for contraception for women aged 25 years and younger
We considered RCTs in any language that reported the contraceptive failure rates for hormonal or intrauterine contraceptive methods, when compared with another contraceptive method, for women aged 25 years and younger. The other contraceptive method could have been another intrauterine contraceptive, another hormonal contraceptive or different dose of the same method, or a non‐hormonal contraceptive. Treatment duration must have been at least three months. Eligible trials had to include the primary outcome of contraceptive failure rate (pregnancy). The secondary outcome was contraceptive continuation rate.
Provide selection criteria that should be included in the study
Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea
All randomised controlled trial (RCT) comparisons of NSAIDs versus placebo, other NSAIDs or paracetamol, when used to treat primary dysmenorrhoea.
Provide selection criteria that should be included in the study
Interventions for pain with intrauterine device insertion
We included RCTs that evaluated an intervention for preventing IUC insertion‐related pain. The comparison could have been a placebo, no intervention, or another active intervention. The primary outcomes were self‐reported pain at tenaculum placement, during IUC insertion, and after IUC insertion (up to six hours).
Provide selection criteria that should be included in the study
Doctors or mid‐level providers for abortion
Randomised controlled trials (RCTs) (clustered or not clustered), prospective cohort studies or observational studies that compared the safety or effectiveness (or both) of any type of first trimester abortion procedure, administered by any type of mid‐level provider or doctors, were eligible for inclusion in the review.
Provide selection criteria that should be included in the study
Immediate postpartum insertion of intrauterine device for contraception
We sought randomized controlled trials (RCTs) with at least one treatment arm that involved immediate IUC placement (i.e., within 10 minutes of placenta delivery). Comparison arms could have included early postpartum insertion (from 10 minutes postplacental to hospital discharge) or standard insertion (during a postpartum visit). Trials could also have compared different IUC methods or insertion techniques. Delivery may have been vaginal or cesarean. Primary outcomes were placement (insertion), subsequent expulsion, and method use at study assessment.
Provide selection criteria that should be included in the study
Invasive urodynamic studies for the management of lower urinary tract symptoms (LUTS) in men with voiding dysfunction
Randomised and quasi‐randomised trials comparing clinical outcomes in men who were and were not investigated with the use of invasive urodynamics, or comparing one type of urodynamics against another, were included. Trials were excluded if they did not report clinical outcomes.
Provide selection criteria that should be included in the study
Preoperative ripening of the cervix before operative hysteroscopy
Two review authors independently selected randomised controlled trials (RCTs) of cervical ripening agents used before operative hysteroscopy in pre‐ and postmenopausal women. Cervical ripening agents could be compared to each other, placebo or no treatment.
Provide selection criteria that should be included in the study
Add‐back therapy with GnRH analogues for uterine fibroids
Randomized controlled trials (RCTs) that included women with uterine fibroids experiencing irregular or intense uterine bleeding, cyclic or non‐cyclic pelvic pain, or urinary symptoms, and that compared treatment with a GnRH analogue plus add‐back therapy versus a GnRH analogue alone or combined with placebo were eligible for inclusion.
Provide selection criteria that should be included in the study
Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence
Randomised and quasi‐randomised trials of transurethral radiofrequency collagen denaturation versus no treatment/sham treatment, conservative physical treatment, mechanical devices, drug treatment, injectable treatment for UI or other surgery for UI in women were eligible.
Provide selection criteria that should be included in the study
Hormone therapy for preventing cardiovascular disease in post‐menopausal women
RCTs of women comparing orally administered hormone therapy with placebo or a no treatment control, with a minimum of six months follow‐up.
Provide selection criteria that should be included in the study
Nitric oxide donors for cervical ripening in first‐trimester surgical abortion
Randomised controlled trials comparing NO donors alone or in combination with other methods for cervical ripening in first‐trimester surgical abortion.
Provide selection criteria that should be included in the study
Conservative management for postprostatectomy urinary incontinence
Randomised or quasi‐randomised controlled trials evaluating conservative interventions for urinary continence in men after prostatectomy.
Provide selection criteria that should be included in the study
Imiquimod for anogenital warts in non‐immunocompromised adults
Randomized controlled trials (RCTs) comparing the use of imiquimod with placebo, any other patient‐applied or any other provider‐administered treatment (excluding interferon and 5‐fluorouracil which are assessed in other Cochrane Reviews) for the treatment of AGW in non‐immunocompromised adults.
Provide selection criteria that should be included in the study
Minimally invasive surgical techniques versus open myomectomy for uterine fibroids
All published and unpublished randomised controlled trials comparing myomectomy via laparotomy, mini‐laparotomy or laparoscopically assisted mini‐laparotomy versus laparoscopy or hysteroscopy in premenopausal women with uterine fibroids diagnosed by clinical and ultrasound examination were included in the meta‐analysis.
Provide selection criteria that should be included in the study
Types of indwelling urethral catheters for short‐term catheterisation in hospitalised adults
We included all randomised controlled trials (RCTs) and quasi‐RCTs comparing types of indwelling urethral catheters for short‐term catheterisation in hospitalised adults. 'Short‐term' is defined as a duration of catheterisation which is intended to be less than or equal to 14 days.
Provide selection criteria that should be included in the study
Non‐surgical interventions for the management of chronic pelvic pain
Randomised controlled trials (RCTs) on non‐surgical management of chronic pelvic pain were eligible for inclusion. We included studies of women with a diagnosis of pelvic congestion syndrome or adhesions but excluded those with pain known to be caused by endometriosis, primary dysmenorrhoea (period pain), active chronic pelvic inflammatory disease or irritable bowel syndrome. We considered studies of any non‐surgical intervention, including lifestyle, physical, medical and psychological treatments.
Provide selection criteria that should be included in the study
Pre‐operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding
Randomised controlled trials (RCTs) were included if they compared the effects of these agents with one other, or with placebo or no treatment, on relevant intraoperative and postoperative treatment outcomes. Selection of trials was carried out independently by two review authors.
Provide selection criteria that should be included in the study
Aromatase inhibitors for uterine fibroids
Randomised controlled trials (RCTs) in women of reproductive age comparing the effects of any AI versus placebo, no treatment or any medical treatment/surgery were included.
Provide selection criteria that should be included in the study
Paracervical local anaesthesia for cervical dilatation and uterine intervention
We included randomized or controlled clinical studies involving women who underwent cervical dilatation and uterine intervention for obstetrics and gynaecological conditions. We included studies which compared paracervical anaesthesia with no treatment, placebo, other methods of regional anaesthesia, systemic sedation and analgesia, or general anaesthesia.
Provide selection criteria that should be included in the study
Prophylactic antibiotics for transcervical intrauterine procedures
We planned to include only truly randomised controlled trials that compared antibiotic prophylaxis with placebo or no treatment in order to prevent infectious complications after transcervical intrauterine procedures. Controlled clinical trials without randomisation and pseudo‐randomised trials were excluded.
Provide selection criteria that should be included in the study
Anti‐TNF‐α treatment for pelvic pain associated with endometriosis
Randomised controlled trials (RCTs) comparing anti‐TNF‐α drugs with placebo, no treatment, medical treatment, or surgery for pelvic pain associated with endometriosis were included.
Provide selection criteria that should be included in the study
Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers
We included randomised controlled trials (RCTs) and non‐RCTs, including controlled before‐after (CBA) trials, interrupted time series, and cross‐over trials. Eligible trials evaluated any of the following shift schedule components.• Permanency of shifts
• Regularity of shift changes
• Direction of shift rotation
• Speed of rotation
• Shift duration
• Timing of start of shifts
• Distribution of shift schedule
• Time off between shifts
• Split shifts
• Protected sleep
• Worker participationWe included studies that assessed sleep quality off‐shift, sleep duration off‐shift, or sleepiness during shifts.
Provide selection criteria that should be included in the study
Splinting for carpal tunnel syndrome
Randomised trials were included if the effect of splinting could be isolated from other treatment modalities. The comparisons included splinting versus no active treatment (or placebo), splinting versus another disease‐modifying non‐surgical treatment, and comparisons of different splint‐wearing regimens. We excluded studies comparing splinting with surgery or one splint design with another. We excluded participants if they had previously undergone surgical release.
Provide selection criteria that should be included in the study
Collective leadership to improve professional practice, healthcare outcomes and staff well‐being
Two groups of two authors independently reviewed, screened and selected studies for inclusion; the principal author was part of both groups to ensure consistency. We included randomised controlled trials (RCTs) that compared collective leadership interventions with usual centralised leadership or no intervention.
Provide selection criteria that should be included in the study
Pre‐deployment programmes for building resilience in military and frontline emergency service personnel
Only studies that used a randomised controlled trial (RCT)/cluster‐RCT methodology were included. The programmes being evaluated must have sought to build resilience prior to exposure to trauma. Study participants must have been 18 years or older and be military personnel or frontline emergency workers.
Provide selection criteria that should be included in the study
Exercise therapy for chronic low back pain
We included randomised controlled trials that assessed exercise treatment compared to no treatment, usual care, placebo or other conservative treatment on the outcomes of pain or functional limitations for a population of adult participants with chronic non‐specific low back pain of more than 12 weeks’ duration.
Provide selection criteria that should be included in the study
Interventions to improve return to work in depressed people
We included randomised controlled trials (RCTs) and cluster‐RCTs of work‐directed and clinical interventions for depressed people that included sickness absence days or being off work as an outcome. We also analysed the effects on depression and work functioning.