Desmopressin Acetate   
Nasal Solution, 0.01%

A BETTER WAY TO DELIVER DESMOPRESSIN ACETATE NASAL SOLUTION

DELIVERING DESMOPRESSIN ACETATE MORE EFFICIENTLY

Your doctor has prescribed desmopressin acetate nasal solution as antidiuretic hormone replacement therapy. Follow the dosage schedule that is specified. The convenient nasal spray pump provides an efficient, reliable way to administer your medication. It is important, however, to adhere completely to the following instructions so that you will always receive a consistent dose of your medication.

CAUTION: The nasal spray pump accurately delivers 50 sprays of 10 micrograms each. Any solution remaining after 50 sprays should be discarded since the amount delivered in each spray thereafter may be substantially less than 10 micrograms of the drug. Do not transfer any remaining solution to another bottle. Please read the following instructions carefully before using the spray pump.

Ensure that in children administration is under adult supervision in order to control the dose intake.

If you accidentally deliver/administer too much of a dose, immediately telephone your doctor or a certified Regional Poison Center for advice. Possible signs of overdose may include confusion, drowsiness, continuing headache, problems with passing urine and rapid weight gain due to fluid retention.

USING YOUR DESMOPRESSIN ACETATE NASAL SPRAY PUMP

  1. Remove protective cap.
  2. The spray pump must be primed prior to the first use. To prime the pump, hold the bottle as shown in Figure A and press down with a quick and firm motion a total of five (5) times. This initial priming is very important to assure you receive the correct amount of the solution when you begin to administer the product. The bottle is filled with extra solution to accommodate for this priming activity.
  3. Once primed, the spray pump will deliver the correct amount of solution each time it is pressed. To administer, hold bottle upright as shown in Figure A and place the spray nozzle in nostril. Then press the spray pump once with a quick and firm motion. To ensure dosing accuracy, it is very important to hold the bottle upright while administering the solution; it may be necessary to lean your head slightly forward so as to not tilt the bottle. Tilting the bottle, especially when less than half of the solution is left, may cause the pump to not dispense correctly. NOTE - If necessary, clear nasal passages before administering.  


  4. If a higher dose (or more than one spray) is prescribed, spray half the dose in each nostril. For example, if 4 sprays are prescribed, administer two sprays into each nostril. Please note that the spray pump cannot be used for doses less than 10 micrograms or doses other than multiples of 10 micrograms.
  5. Replace the protective cap on bottle after use and store in the refrigerator in an upright position. The pump will stay primed for up to one week under refrigeration. If the product has not been used for a period of one week, re-prime the pump by pressing once.
  6. We have included a convenient check-off chart to assist you in keeping track of the number of sprays (doses) used. This will help assure that you receive the labeled 50 sprays (doses) after the initial priming activity. As mentioned above, please discard any remaining solution after administering the 50 sprays as the correct dosage cannot be assured past this point.



Storage: Store in refrigerator at 2°-8°C (36°-46°F). When traveling, product will maintain stability for up to 3 weeks when stored at room temperature, 22°C (72°F).