anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
In the first 10 days following recruitment, participants met with the research coordinator and were provided with an accelerometer (GT3X) and completed self-report baseline measures. Provided along with the RiseTx application is the Jawbone, which is a wrist-worn device that can assess activity patterns throughout the day and provide sensory alerts to stand after prolonged sitting (i.e., ≥30 minutes of sedentary time). The intervention consisted of five phases following initial data collection, including a baseline phase (weeks 1-2) where participants self-monitored their typical leisure time PA (i.e., step counts) and were asked to 'sync' their Jawbone with the RiseTx application to view their daily progress and steps. This daily self-monitoring process continued over the remaining intervention period. Based on a previously tested ramped step count approach that focuses on increasing walking by an extra 1000 daily steps over a set period, participants attempted to increase daily steps by 1000 over the average of their baseline week. Phases I-III involved progressive release of self-regulatory strategies (e.g., action planning) on the application and targeted changes in both sitting time (and breaks in sitting time) and step counts. Phase I (weeks 3-4) focused on increasing low intensity, incidental movement, through the use of an alerting device, and the Jawbone (reminder to break SED). At this time, an additional +1000 daily step increment was set above baseline. Phase II (weeks 5-6) targeted shorter planned PA (of up to 10 mins) by having participants form action plans on the application for both reducing SED and increasing PA. An additional +1000 daily step increment was set above Phase I. Phase III (weeks 7-8) focused on promoting longer, moderate intensity PA (\>10 min), where participants used the application to form coping plans for barriers to reducing sitting time or engaging in PA. An additional +1000 daily step increment was set above Phase II step target. A 4-week consolidation phase (Phase IV and V; weeks 9-12) followed, where participants received weekly reminders that encouraged them to continue to use the RiseTx application to practice combining the different self-regulatory strategies learned in Phases I-III. Following the intervention, there was a 12-week maintenance period (weeks 13-24) where participants no longer received weekly self-regulatory practice reminders, yet still had access to the application.
One of the above three targets will be randomly selected. The current will be applied for 30 seconds ramp-up followed by 30 seconds ramp-down.
OBJECTIVE: Motor neuron pool activity is high in spasticity. The effect of inhibitory kinesiotaping (KT) on spasticity is unclear. The aim of this study is to investigate the effect of inhibitory KT on spasticity after stroke.
METHODS: Fifty stroke patients with ankle plantarflexor spasticity were randomised to intervention (27) and control (23) groups. Inhibitory KT was applied to the triceps surae muscle in the intervention group and sham KT to the Achilles tendon in the control group. Inhibitory and sham KT were applied for 72 h with a combined conventional rehabilitation programme. Spasticity was assessed at baseline and 72 h after KT using three instruments: Modified Ashworth Scale (MAS), Homosynaptic Post-Activation Depression (HPAD) reflecting the level of motor neuron pool activity, and joint torque as a measure of resistance to passive ankle dorsiflexion.
RESULTS: The baseline MAS score, HPAD levels and dorsiflexion torque of the two groups were not significantly different. The change in MAS score was -3.7 ± 17.5 (p = 0.180) in the intervention group and 3.6 ± 33.3 (p = 0.655) in the control group. The change in dorsiflexion torque was -0.3 ± 16.1 kg m (p = 0.539) in the intervention group and 8.0 ± 24.1 kg m (p = 0.167) in the control group. The change in mean HPAD was 8.7 ± 34.7 (p = 0.911) in the intervention group and 10.1 ± 41.6 (p = 0.609) in the control group.
CONCLUSIONS: The present study showed that inhibitory KT has no antispastic effect in stroke patients.
Infants randomized in to the experimental group will receive the PAL intervention 2 times a week until the infant transitions to room air or \< 2L high flow nasal cannula and is able to begin attempting feeds by mouth. The PAL is an FDA cleared medical device that has a sensor that will connect to the infant's pacifier and can read the infant's suck. Then, the device plays music as positive reinforcement to help improve sucking skills. This intervention typically lasts about 15 minutes and is implemented while the infant is receiving gavage feeds.
The invention discloses conditioning shampoo including a henna powder component. The conditioning shampoo mainly comprises surface active agent, conditioner, foaming agent, citric acid, additive and deionized water. The shampoo is characterized in that the additive is henna powder. Henna is commonly called as impatiens balsamina including natural hairdressing components, such as tannin, flavonoid, tea quinone and the like. The shampoo has special effects for inhibiting dandruff, firming hair root, preventing baldness, hair cut and early white hair, and the like, furthermore, the shampoo is capable of deeply cleaning and nourishing scalp. The shampoo is moderate and can nourish scalp and make hair root nutrient. The shampoo is multifunctional.
The exSALT™ SD7 Wound Dressing provides an antimicrobial barrier that inhibits microbial growth in the dressing. The exSALT™ SD7 Wound Dressing consists of 3 layers: two non-adherent polyethylene mesh wound contact layers and one absorbent core made of polyester. All three layers are silver coated. The concentration of silver on the exSALT™ SD7 Wound Dressing is approximately 0.4 mg/cm2 (2.5% w/w).
In the control group, observation will be conducted solely by another anesthesia doctor or assistant participating in the study, and the data will be recorded blindly without being reported to the anesthesia doctor responsible for the surgery. The oxygen therapy administered by the anesthesia doctor in charge and the FiO2 values will be recorded independently and blindly, based solely on the clinician's own assessment, rather than according to the information obtained from ORi. Subsequently, for two days following the surgery, evaluations will be conducted twice daily at the same hours for ward patients using CAM, and for ICU patients using CAM-ICU. If delirium is detected, delirium subtyping will be performed using the Richmond Agitation-Sedation Scale (RASS).
OBJECTIVE: To assess the prevalence of brain abscesses as a confounding factor for the diagnosis of post-traumatic epilepsy (PTE) in a rat model of lateral fluid-percussion-induced (FPI) traumatic brain injury (TBI).
METHODS: This retrospective study included 583 rats from 3 study cohorts collected over 2009-2022 in a single laboratory. The rats had undergone sham-operation or TBI using lateral FPI. Rats were implanted with epidural and/or intracerebral electrodes for electroencephalogram recordings. Brains were processed for histology to screen for abscess(es). In abscess cases, (a) unfolded cortical maps were constructed to assess the cortical location and area of the abscess, (b) the abscess tissue was Gram stained to determine the presence of gram-positive and gram-negative bacteria, and (c) immunostaining was performed to detect infiltrating neutrophils, T-lymphocytes, and glial cells as tissue biomarkers of inflammation. In vivo and/or ex vivo magnetic resonance images available from a subcohort of animals were reviewed to evaluate the presence of abscesses. Plasma samples available from a subcohort of rats were used for enzyme-linked immunosorbent assays to determine the levels of lipopolysaccharide (LPS) as a circulating biomarker for gram-negative bacteria.
RESULTS: Brain abscesses were detected in 2.6% (15/583) of the rats (6 sham, 9 TBI). In histology, brain abscesses were characterized as vascularized encapsulated lesions filled with neutrophils and surrounded by microglia/macrophages and astrocytes. The abscesses were mainly located under the screw electrodes, support screws, or craniectomy. Epilepsy was diagnosed in 60% (9/15) of rats with an abscess (4 sham, 5 TBI). Of these, 67% (6/9) had seizure clusters. The average seizure frequency in abscess cases was 0.436 ± 0.281 seizures/d. Plasma LPS levels were comparable between rats with and without abscesses (p > 0.05).
SIGNIFICANCE: Although rare, a brain abscess is a potential confounding factor for epilepsy diagnosis in animal models of structural epilepsies following brain surgery and electrode implantation, particularly if seizures occur in sham-operated experimental controls and/or in clusters.
The present invention discloses a mixture for an anti-oxidant and liver protection function and a method thereof. The mixture comprises an extraction of Rhinacanthus nasutus L. Kurz, an extraction of Vitis thunbergii Sieb. et Zucc. and an extraction of Salvia plebeia R. Brown. The extraction of Rhinacanthus nasutus L. Kurz, the extraction of Vitis thunbergii Sieb. et Zucc. and the extraction of Salvia plebeia R. Brown are mixed by a predetermined ratio, and the predetermined ratio can be 15 to 60 wt%: 15 to 60 wt%: 15 to 60 wt%.
Bookmarking content modules and tracking scores of user properties against the bookmarked content modules on a computer implemented social network are provided. Content modules containing text, audio, video, or audio-video content are accessible to users of a social network. User properties are associated with the users of the social network and the user properties are related to the content modules. Each user of the social network can bookmark a content module and score a user property against the bookmarked content module related with the same user property. Scores are tracked over a period of time to provide motivation and accountability to the user. Ad hoc online communities form around the bookmarked content modules; members of an online community all share at least one common bookmarked content module. A messaging function is provided for members of an online community to communicate with each other to foster support and accountability.
The communication mechanism of the gut-lung axis has received increasing attention in recent years, particularly in acute respiratory infectious diseases such as influenza. The peripheral immune system serves as a crucial bridge between the gut and the lungs, two organs that are not in close proximity to each other. However, the specific communication mechanism involving gut microbiota, immune cells, and their anti-influenza effects in the lung remains to be further elucidated. In this study, the effects of 731 species of peripheral immune cells and 211 different gut microbiota on influenza outcomes were analyzed using a two-sample Mendelian randomization analysis. After identifying specific species of gut microbiota and peripheral immune cells associated with influenza outcomes, mediation analyses were conducted to determine the mediating effects of specific immune cells in the protective or injurious effects of influenza mediated by gut microbiota. 19 species of gut microbiota and 75 types of peripheral immune cells were identified as being associated with influenza susceptibility. After rigorous screening, 12 combinations were analyzed for mediated effects. Notably, the down-regulation of CD64 on CD14- CD16- cells mediated 21.10% and 18.55% of the protective effect of Alcaligenaceae and Dorea against influenza, respectively. In conclusion, focusing on influenza, this study genetically inferred different types of gut microbiota and peripheral immune cells to determine their protective or risk factors. Furthermore, mediation analysis was used to determine the proportion of mediating effects of peripheral immune cells in gut microbiota-mediated susceptibility to influenza. This helps elucidate the gut-lung axis mechanism by which gut microbiota affects influenza susceptibility from the perspective of regulation of peripheral immune cells.
Pertussis toxoid was prepd. by culturing the strain Bordetella pertussis. Thus, Bordetella pertussis was cultured in a liq. medium (for example, Cohen-filter medium) at 35oC for 5-7 days. The resulting culture broth was filtered and concd. The supernatant was treated with ammonium sulfate and the resulting ppt. was dissolved in lM NaC1-0.05M phosphate buffer soln. Endotoxin of the soln. was removed by sucrose density gradient centrifugation (gravity=62000-122000xg; sucrose conc.=0-60 wt/wt% for 10-24 hr). Exotxin was reacted with formaldehyde without basic amino acids to give clotted mon-toxic vaccine, which has immunogenic activity protecting babies against pertussis.
Patients undergoing previously scheduled rest or stress echocardiography with the primary investigator as the supervising physician will be identified and consented. The standard stress echocardiography procedure will be performed. Definity® or LUMASON will be removed from refrigeration and agitated for 45 seconds to vaporize into its gaseous phase. One mL of Definity® or LUMASON will then be diluted in 29 mL of isotonic, sterile saline. Patients will undergo baseline echocardiography followed by stress with either dobutamine or exercise. Standard Definity® or LUMASON will be injected intravenously into the subject via peripheral intravenous access obtained prior to the study by a registered nurse at the end of the rest or stress portion of the procedure coinciding with image acquisition. Contrast enhanced echocardiography by standard acoustic acquisition will be performed following rest or stress for the indicated diagnostic purpose of the test. By the end of the exam, the gaseous Definity® or LUMASON will have undergone manual compression via manual pressure and condensed back to its liquid phase. At this point, the compressed Definity® or LUMASON will be given intravenously with repeated transthoracic echocardiography. During this second round of image acquisition, real time (RT) imaging (35 Hertz) and 1:1 triggered (Tr) end systolic imaging at various mechanical indices (MI's) up to 1.2 will be performed in standard transthoracic echocardiography windows. Acoustic Intensity (AI) within the left ventricular (LV) cavity, the anterior myocardium (AM) and inferolateral myocardium (ILM) at end systole will be obtained at each MI setting with real time or triggered imaging. Differences in AI between Tr and RT imaging within the AM and ILM at each MI will be used to quantify bubble activation/destruction. Following image acquisition, the patient will be observed for 30 minutes by echo lab staff with nearby resuscitative equipment per current protocol. If no adverse events are noted, the patient will then be dismissed.
Patients will be informed about the study including potential risk and benefits. Once written informed consent are obtained, patients will undergo a brief screening period to determine eligibility for the study. Once eligibility is confirmed, eligible patients will be placed in a randomized placebo control manner. Patient will be assigned to Xlear (2 puffs per nostrils, every 3-4 hours a day) or placebo. Patient will be followed for 1 week. Inflammatory markers will be obtained on Day 4 and repeat COVID-19 Reverse Transcriptase PCR (RT PCR) on Day 7. Follow up will be done on Day 14 for all patients.
PURPOSE:To obtain a carcinostatic agent comprising 2'-deoxy-2'-methylidene cytidine or an acid addition salt thereof as an active ingredient. CONSTITUTION:A carcinostatic agent containing a compound shown by the formula or an acid addition salt thereof (e.g. inorganic salt such as hydrochloride or hydrobromide and organic acid salt such as maleate) as an active ingredient. Powder, granule, tablet, sugar coated tablet, capsule, syrup, suppository, external preparation, injection or agent for drip may be cited as the dosage form. Oral administration is especially preferable. A dose is 10-400mg/kg/day, preferably 50-200mg/kg/day in the case of oral agent and 1-10mg/kg/day, preferably 1-5mg/kg/day in the case of injection. The number of times of administration is once-four times daily and can be properly selected. The carcinostatic agent can be used with another carcinostatic agent, immunoactivator or other drugs.
FIELD: medicine. SUBSTANCE: method involves treating inflammation focus with aerosol jet by applying high frequency insufflation techniques. Speed is selected to be equal to 100-120 cycles per min; pressure is 25-40 mm of mercury column large. Treatment duration is 5-7 min. The number of sessions is 6-9. Aerosol has oxygen, local anesthetic agents, antiseptic agents, fibrinolytic agents, and antihistamine preparations when dealing with fibrinous exudate. Fibrinous purulent or purulent exudate being the case, aerosol has oxygen, local anesthetic agents, antiseptic agents, glucocorticoids, immunomodulator agents, antibiotics and antihistamine preparations. EFFECT: enhanced effectiveness of treatment; prevented infection generalization over the abdominal cavity. 3 cl
A system and method of generating an enhanced Lund and Browder chart and total body surface area burn score is described herein. In some embodiments, a plurality of images is obtained from of a patient using a camera system. The images may be taken by aligning the patient's body with pose templates presented on a display of the camera system. The non-skin portions of the images may be removed, and skin analysis performed on the skin portion to determine burn location, coverage, and depth. Further, landmarks may be detected in the images to morph and align the images with the pose templates to obtain standard poses. The plurality of images may be combined and presented in two-dimensional and three-dimensional models with labels and the total surface area burn score.
FIELD: medicine, rheumatology. SUBSTANCE: method could be applied in treating patients with articular syndrome in complex therapy. The method includes basic therapy and impact of leeches onto articular area with synovitis signs at 2-7-d-long interval, therapy course being not less than 2 seances by using about 2-7 leeches/seance. The method provides decreased activity of process, interruption of synovitis along with simplicity and cheapness. EFFECT: higher efficiency of therapy. 3 ex
The present invention belongs to medicine for treating rheumatism and rheumatoid disease, which provides pure Chinese medicine preparation for treating the rheumatism and the rheumatoid disease. The present invention has the key point that the Chinese medicine preparation of the present invention is composed of orientvine stems, futokadsura stems, clematis roots, spinyleaf pricklyash roots, beautiful millettia roots, pubescent angelica roots, gall roots, boston ivy, shave grass, common floweringquince roots, madder roots, cocklebur fruit, bupleurum roots, caulis polygoni multiflori, dahurian angelica roots, pueraria roots and grassleaved sweetflag rhizomes. All the medicine is prepared with crude medicine; each kind of medicine has the proportion by weight of 3 to 5. The preparation has the functions of eliminating swelling, promoting tissue regeneration, dredging channels, dispelling wind, eliminating dampness, nourishing livers and kidneys, strengthening bones and muscles, stretching joints and relieving crymodynia. Compared with the prior art, the present invention has no anaphylaxis and has no poison and side effects on human bodies; the cure rate is over 90%. The medicine has the advantages of richness and easy acquisition of medicinal resources, low price and economy for patients.
Subjects with bilateral cam deformity and unilateral symptoms. All patients will undergo all 3 interventions: MRI, qCT, and motion analysis. Select patients will be asked to participate in a PET-MRI scan being conducted at The Royal Ottawa.
PURPOSE: A functional cosmetic composition for anti-aging is provided to suppress MMP-1 biosynthesis and to promote biosynthesis of type 1 procollagen, thereby improving skin elasticity and anti-wrinkling effect. CONSTITUTION: A method for preparing an Ulva spp. seaweed hydrolysate comprises the steps of: extracting dried and pulverized Ulva spp. seaweed using hot water and preparing a soluble extract; adding ethyl alcohol to the soluble extract and precipitating polysaccharides and proteins; filtering and centrifuging the soluble extract to collect the precipitate; selectively collecting Ulva spp. Seaweed-containing polysaccharides; dispersing the polysaccharides in a volatile acid solution and filtering to obtain an Ulva spp. seaweed hydrolysate; and removing acid and solvents from the Ulva spp. seaweed hydrolysate. A cosmetic composition contains 0.001-30.0 wt% of the Ulva spp. seaweed hydrolysate as an active ingredient, containing 1.0 % of glucoronic acid.
Mindfulness-Based Stress Reduction (MBSR) tis designed to provide education about mindfulness and stress; experiential mindfulness practice, and discussion of participants' experiences with mindfulness practice. MBSR is delivered in 8 weekly 2.5-hour group sessions and one day-long retreat that occurs after the 6th session.
Lateral epicondylitis is a common upper extremity disease that occurs with tenderness in the lateral epicondyle, the common attachment point of the wrist extensor muscles, and pain during resisted wrist extension. It is usually a non-inflammatory tendinopathy of the extensor carpi radialis and extensor digitorum comminis. Calcific tendinitis and/or partial tears in the wrist extensor muscles may accompany this condition. It is most common between the ages of 30-60 and its prevalence has been reported as 1-1.7% Although the underlying cause is mostly unknown, activities that involve excessive use of wrist extensors and supinators are thought to be the most important cause of lateral epicondylitis .The main purpose of treating lateral epicondylitis is to reduce pain and increase functionality, but there is no accepted standard treatment method. Non-surgical treatment approaches such as patient education physiotherapy applications, manual therapy, laser therapy, splinting, taping, exercises, massage and local injection, as well as oral or topical nonsteroidal anti-inflammatory drugs are frequently applied. Kinesio tape, which is frequently used in musculoskeletal system injuries, is flexible, mimics skin and has a water-resistant structure. Kinesio tape creates a pumping system by pulling the skin up in the area where it is applied, thus increasing the skin space, increasing blood and lymph circulation, and creating analgesia and proprioceptive sensory input by reducing the pressure on pain receptors . There are scientific studies showing that kinesio tape application reduces pain and increases functionality and grip strength in patients with lateral apicondylitis. It is stated that high-intensity laser treatment can quickly create photochemical and photothermic effects in deep tissue. For this reason, collagen production in tendons is stimulated and can increase blood flow, vascular permeability and cell metabolism. As a result of all these events, tissue healing begins and painful stimuli disappear. It has been shown that high-intensity laser reduces pain and increases functionality and grip strength in patients with lateral epicondylitis. In the literature review, no randomized controlled studies were found comparing high-intensity laser and kinesio tape applications in patients with lateral epicondylitis