anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
A hair grooming composition comprises a polyamide, which is the reaction product of an aliphatic polycarboxylic acid and an alkylene polyamine and has an average M.W. between 2000 and 14,000, at least partly dissolved in a liquid, oily, non-polar solvent consisting of or including a substance having a chain of at least 10 C atoms in its molecule, e.g. mineral oil.  The composition may include an alcohol, a fatty acid, or a glycol ester as a co-solvent, and a fatty acid amide having a chain of at least 10 C atoms as a stabilizer.ALSO:Aerosol hair grooming compositions comprise a polyamide material at least partly dissolved in a liquid, oily, non-polar solvent consisting of or including a subtance having a chain of at least 10 C atoms in its molecule, the polyamide material being a reaction product of an aliphatic poly-carboxylic acid and an alkylene polyamine and having an average M.W. between 2000 and 14,000 and a suitable propellant.  A typical composition comprises a polyamide of average M.W. 8000, ethyl alcohol, lanolin oil, propylene glycol monolaurate, and perfume together with trichloromonofluoromethane and dichlorodifluoromethane.ALSO:A hair grooming composition comprises a polyamide material at least partly dissolved in a liquid, oily, non-polar solvent consisting of or including a substance having a chain of at least 10 C atoms in its molecule, the polyamide material being a reaction product of an aliphatic poly-carboxylic acid and an alkylene polyamine and having an average M.W. between 2000 and 14000.  The liquid, oily, nonpolar solvent may be a mineral oil. The compositions may include an alcohol, a fatty acid, or a glycol ester as a co-solvent and a fatty acid amide having a chain of at least 10 C atoms as a stabilizer. The compositions may be in the form of gels, lotions, brilliantines, emulsions, or aerosols.  The invention also comprises a method of grooming hair comprising the step of applying the above hair grooming composition to the hair.
The study was planned as a randomized controlled study. Volunteer participants over the age of 65 living in a nursing home in Ankara will be included in the study. The sample of the study will consist of 28 elderly individuals, as determined by power analysis. The participants will be randomly divided into two groups. One group (Group 1) will receive functional balance exercise training, and the other group (Group 2) will receive functional balance-based reaction exercise training. The participants socio-demographic information, cognitive level ( The Montreal Cognitive Assessment), executive function (Stroop Test), reaction time, physical performance (Four Step Square test, Short Physical Performance Battery, Time Up Go Test) and balance confidence (Falls Efficiency Scale) will be evaluated Evaluations will be repeated at baseline and 8 weeks later. The interventions will be carried out two days a week for 40 minutes for eight weeks.
Participants receive Certoparin 3,000 IU during period 1. Participants will receive 8,000 IU during period 2, if qualified as per medical criteria.
Precipitated silica which has a BET surface area of 10-130 m2/g, a CTAB surface area of 10-70 m2/g, an average particle diameter of 5-20 µm, a Cu abrasion value in a 10% glycerol dispersion of 4-50 mg and thickening behavior in a CMC solution (20% dispersion) of 300-3500 mPa.s, is produced by this invention.  The process comprises simultaneously adding alkali metal silicate (weight modulus SiO2:alkali metal oxide = 2.5-3.9:1) and a mineral acid to an initial amount of water which has been adjusted to a pH value of 7.0 to 9.9 or 10.0 to 10.7 by the addition of water glass (sodium silicate).  The pH value is held constant between 7.0 to 9.9 or 10.0 to 10.7 during addition of the alkali metal silicate and mineral acid.  The initial precipitation temperature is 50°-90° C. and an increase in viscosity occurs after at most 25% of the duration of precipitation.  The pH value is adjusted to ~ 6, preferably 3.5, once a silica content of greater than 120 g/l or greater than 150 g/l, preferably ~ 160 g/l to 240 g/l, has been reached.  The solid is separated by filtration, washed, dried and ground.  The precipitated silica may be used as an abrasive and/or thickening component in toothpastes.
Belumosudil is a kinase inhibitor. The active pharmaceutical ingredient is belumosudil mesylate with the molecular formula C27H28N6O5S and the molecular weight is 548.62 g/mol. The chemical name for belumosudil mesylate is 2-{3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy}-N-(propan-2-yl) acetamide methanesulfonate (1:1). The chemical structure is as follows:

Belumosudil mesylate is a yellow powder that is practically insoluble in water, slightly soluble in methanol and DMF and soluble in DMSO.

REZUROCK tablets are for oral administration. Each tablet contains 200 mg of the free base equivalent to 242.5 mg of belumosudil mesylate. The tablet also contains the following inactive ingredients: microcrystalline cellulose, hypromellose, croscarmellose sodium, colloidal silicon dioxide, and magnesium stearate.

The tablet film consists of polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide and yellow iron oxide.
To provide an information processing system and the like which enable more correct transmission or sharing of information related to a medical procedure.SOLUTION: There is provided an information processing system according to an embodiment of the present invention. The information processing system comprises a control unit. The control unit is configured to execute the following steps. A read-out step reads out reference information about a reference procedure being a medical procedure to be preferably referred by a user. The reference information includes a three-dimensional position of a tracked portion in the reference procedure. The first reception step receives a photographed image obtained by imaging an external field visually recognized by the user. The generation step generates display information for presenting the augmented reality about the reference procedure to the user on the basis of the three-dimensional position of the tracked portion and the photographed image. In the augmented reality, a mode of a medical instrument used in the reference procedure or a hand operating the medical instrument is three-dimensionally reproduced.SELECTED DRAWING: Figure 6
Revascularization of necrotic anterior teeth: canals disinfection step. Mix 1:1 ciprofloxacin: metronidazole to a final concentration of 0.1 mg/ml, placed as intra-canal medication in the 1st visit of dental pulp revascularization.
1. An immunogenic composition which comprises a first malaria-derived peptide comprising a universal T-cell epitope, wherein said universal T-cell epitope: a). has a pattern of aliphatic and aromatic residues identical peptide the sequence EYLNKIQNSLSTEWSPCSVT (SEQ ID NO:3) b). is a derivative from the circumsporozoite (CS) protein of a plasmodial species; and c). binds to a multiplicity of MHC class II molecules, wherein said composition elicits an antimalarial T-cell response in mammals of diverse genetic backgrounds. 2. An immunogenic composition as defined in claim 1, further comprising a second malaria-derived peptide comprising a B-cell epitope which stimulates the production of anti-malarial antibodies in mammals. 3. An immunogenic composition as defined in claim 1, wherein said first peptide is incorporated into a multiple antigen peptide. 4. An immunogenic composition as defined in claim 2, wherein said first and second peptides are incorporated into a multiple antigen peptide. 5. An immunogenic composition as defined in claim 1, wherein said first peptide comprises the sequence EYLNKIQNSLSTEWSPCSVT. 6. A vaccine comprising an immunogenic composition as defined in claim 1 and a pharmaceutically acceptable carrier or diluent. 7. A vaccine as defined in claim 7, further comprising a pharmaceutically acceptable adjuvant. 9. A method for inhibiting the propagation of a malarial organism in a susceptible mammal, which comprises administering to said mammal an immunogenically effective amount of a vaccine as defined in claim 6. 10. An immunogenic composition which comprises a first malaria-derived peptide comprising the sequence EYLNKIQNSLSTEWSPCSVT, wherein said composition elicits an anti-malarial T-cell response in mammals of diverse genetic backgrounds. 11. An immunogenic composition as defined in claim 10, further comprising a second malaria-derived peptide comprising a B-cell epitope which stimulates the production of anti-malarial antibodies in mammals. 12. A vaccine comprising an immunogenic composition as defined in claim 10 and a pharmaceutically acceptable carrier or diluent. 13. A vaccine as defined in claim 12, further comprising a pharmaceutically acceptable adjuvant. 14. A method for inhibiting the propagation of a malarial organism in a susceptible mammal, which comprises administering to said mammal an immunogenically effective amount of a vaccine as defined in claim 12. 15. A method for eliciting protective immunity against malaria in a mammal, which comprises administering to said mammal an immunogenically effective amount of a vaccine as defined in claim 12.
BACKGROUND: The treatment of patients with infective endocarditis (IE) who have preoperative cerebral complications remains less understood. Therefore, this study aimed to retrospectively evaluate the clinical outcomes of patients with acute IE based on preoperative intracranial findings.
METHODS: Of 32 patients with acute IE treated at our hospital between August 2015 and March 2022, 31 patients of whom preoperative intracranial imaging evaluation was available were included in our analysis and compared with those with and without intracranial findings. We controlled the mean arterial blood pressure and activated clotting time (ACT) to prevent abnormally high perfusion pressures and ACTs during cardiopulmonary bypass (CPB). The preoperative background, and postoperative courses focusing on postoperative brain complications were reviewed.
RESULTS: Among the 31 patients, 20 (65%) had preoperative imaging findings. The group with intracranial findings was significantly older, with more embolisms in other organs, positive intraoperative pathology findings, and longer CPB times. A new cerebral hemorrhage developed postoperatively in one patient without intracranial findings. There were no early deaths; two patients had recurrent infections in each group, and one died because of sepsis in the late phase in the group with intracranial findings.
CONCLUSIONS: Positive intracranial findings indicated significantly active infectious conditions preoperatively but did not affect the postoperative course. Patients without preoperative cerebral complications can develop serious cerebral hemorrhage. Although meticulous examination of preoperative cerebral complications in all patients with IE is essential, a strategy should be adopted to prevent cerebral hemorrhage, even in patients without intracranial findings.
Stroke is a leading cause of mortality and morbidity. African American (AA) populations have a higher prevalence of stroke than whites do. The lack of resources leads to substantial physical, social, and psychological burdens and makes self-management more challenging, hence putting these individuals at high risk for secondary chronic conditions. This is especially prominent among underserved populations including AA living in the black belt of rural Alabama due to the additional factors related to their socio-demographic characteristics. This pilot project aims develop a need-based community stroke self-management program that would improve the stroke self-management self-efficacy and competencies among African American stroke survivors living in rural Alabama. This is a mixed-methods study to collect data related to the needs of these individuals and develop a need-based intervention based on the actual needs/ preferences of the target population. The specific aims are to assess the needs, access barriers, existing resources for a stroke self-management program; and develop a Community Stroke Self-management Program for improving stroke survivors' abilities to manage their medication adherence, diet, Physical Activity (PA) requirements, symptoms, and psychological distress to better meet their needs, expectations, and preferences. The study also aim to examine the feasibility and acceptability of delivering the CSSP after tailoring our proposed intervention in Aim 2a) among the AA chronic stroke survivors living in rural Alabama. Conducting this study would help to have a sustainable intervention with minimal need of healthcare workers for its online delivery, potentially it would have high scalability and a high economic impact in the long run. Therefore, this project is vital for meeting the unique needs of this underserved population.
A contrast agent and an apparatus for use in magnetic resonance imaging and for treatment by radio frequency pulse for creating a heat spot for cancer treatment, with a process comprising: forming magnetic nanoparticles by depositing at least in part a layer of metal 52 on a core of ferromagnetic material 58, in which the core and the layer of metal are composed of different materials. These may be further deposited in a matrix, e.g. refrigerated water as ice for making a solution of nanoparticles for application on surfaces, avoiding aggregation. The matrix material may be supplied from an MBE source (32, fig 2A) under ultra-high vacuum and may be ground down with the nanoparticles within. The core and/or matrix may comprise a ferromagnetic transition metal, e.g. Iron or Cobalt. These are preferably both in the nanoparticle to improve the magnetic moment by increasing the number of atoms at interfaces in the nanostructure (Fig 1B). The layer may be diamagnetic e.g. Gold or Silver. A matrix or layer may be a rare earth metal e.g. Dy or Ho. The nanoparticle may be a Fe/Co alloy encased in a biocompatible FeO shell. The nanoparticles may comprise a further layer, e.g. actively targeted liposomes, or passive EPR targeting of cancer cells may be used. Diagnosis and therapeutic applications may occur in succession.
It will be used bupivacaine in surgical site prior surgery (25 mg). At least 10 minutes before skin incision.
In patients on corticosteroid therapy subjected to unusual stress, increased dosage of rapidly acting corticosteroids before, during, and after the stressful situation is indicated.

Corticosteroids may mask some signs of infection, and new infections may appear during their use. Infections with any pathogen including viral, bacterial, fungal, protozoan or helminthic infections, in any location of the body, may be associated with the use of corticosteroids alone or in combination with other immunosuppressive agents that affect cellular immunity, humoral immunity, or neutrophil function. 1

These infections may be mild, but can be severe and at times fatal. With increasing doses of corticosteroids, the rate of occurrence of infectious complications increases. There may be decreased resistance and inability to localize infection when corticosteroids are used. 2

Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to fungi or viruses.
A system and method for augmenting healthcare-provider performance employs a head-mounted computing device that includes camera and microphones to capture a patient encounter and events immediately before and after: video, dictation and dialog. Wearing the device by the provider during the encounter permits normal interaction between provider and patient, encouraging the provider to maintain focus on the patient. An “ears-open” earpiece delivers audio data from a remote location without obstructing the ear canal. Augmented reality multimedia is displayed via a heads-up display over the eye(s). Real-time capture of audio and video enables dramatic cost reductions by saving doctor time. Using the system, a doctor no longer need spend hours daily on transcription and EHR entry. A patient encounter is captured and transmitted to a remote station. Relevant parts of the encounter are saved or streamed, and updates to an EHR are entered for provider confirmation after the patient encounter.
The purpose of this study was to investigate an alternative approach to physical activity in people who are morbidly obese to improve their overall health, functional mobility, and quality of life. Although physical activity is recommended in most weight management programs, the type of physical activity that results in the most successful outcomes has not been determined. Walking programs are among the most common forms recommended, however few parameters or guidelines are provided, and well-controlled comparisons to other types of exercise are lacking. Compliance with exercise programs is also a factor that impacts success, therefore offering solutions that improve compliance would be beneficial as well. This study investigated the use of home-based exercise enhanced with DVDs along with weekly, supervised group sessions to compare Tai Chi to a walking program in participants who are morbidly obese.

The participants were recruited from the community with the requirement that they have a body mass index of \>40 and have a diagnosis of morbid obesity. A falls risk screening, the Four Square Step Test (FSST), was performed on which they must score as a low fall risk. A battery of physical and paper tests will be completed prior to starting the study to assess balance, endurance, functional lower extremity strength, and quality of life. Both groups completed a self-report of their weekly physical activity that was submitted on an Activity Log. Those who were designated to be in the control group did not have any additional interaction with the study until week 10 when they returned for post-testing. The Tai Chi intervention group met one time per week as a group to practice Tai Chi with the DVD as the guide. Physical therapy students and faculty were present at each session to modify and supervise as needed. The intervention group also followed the DVD in the home setting for 2 additional sessions each week. Following the 8 weeks of structured classes and home activity, the participants returned the following week for the post-testing session.
Up to 15 participants will be assigned to Regimen 3. Regimen 3 participants will be administered 8 mg aflibercept injections according to the Regimen 3 dosing schedule.
The starting dose was 1 ng/kg/min (not to exceed to 2 ng/kg/min) and was titrated by up to 2 ng/kg/min every 2 hours, as tolerated and clinically indicated by the Investigator. Doses were titrated and maximized throughout the study until the desired clinical effect was observed or to each individual subject's maximally tolerated dose. There was no maximum dose.
The participants in the Active Control arm (AC) will undergo 48 sessions over 24 weeks. The sessions are scheduled three times a week for the first 12 weeks and then once a week for the subsequent 12 weeks. Sessions are spaced at least one day apart and will take about one hour per session. Participants in this arm will view informative documentaries on an electronic tablet and answer three general questions about documentary.
The analysis of cardiac wall mechanics is of importance for understanding coronary heart diseases (CHD). The inhalation of ultrafine particles could deteriorate CHD. The aim of the study is to investigate the effects of cardiac wall mechanics on rats of myocardial infarction (MI) after long-term inhalation of ultrafine Zn particles. Cardiac wall stresses and strains were computed, based on echocardiographic and hemodynamic measurements. It was found that MI resulted in the significantly elevated stresses and the reduced strains. The short-term inhalation of ultrafine Zn particles decreased stresses and increased strains in MI rats, but the long-term inhalation had the opposite effects. Hence, the short-term inhalation of ultrafine Zn particles could alleviate the MI-induced LV dysfunction while the long-term inhalation impaired it.
Inflammation of the posterior segment of the eye is a severe condition and hard to cure as delivery of drugs to the inflammation site is inefficient. Currently, the primary treatment approach is ocular surgery or invasive ocular injections. Herein, we designed and developed a topically self nano-emulsifying drug delivery system (SNEDDs) to deliver triamcinolone acetonide (TCA) to the posterior segment of the eye. A screening based on TCA solubility was conducted on each excipient followed by preparation of various formulations using different ratios of the selected excipients. Vesicles of optimized SNEDDs had less than 100 nm size and spherical morphology. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay showed self-emulsified vesicles have relatively high safety on retinal pigment epithelium (RPE) cell line. Furthermore, efficient cellular uptake of coumarin 6-loaded SNEDDs in RPE using confocal laser scanning microscopy (CLSM) was confirmed. In addition, an in-vivo study using hematoxylin and eosin (H&E) staining revealed that 14 days of topical treatment of albino rabbit eyes with TCA-loaded SNEDDs was safe and no sign of tissue destruction and inflammation was detected in different parts of the eye sections including cornea, sclera, retina, and optic nerve. Also, the CLSM images from topically treated eyes with coumarin 6 (a hydrophobic, fluorescent drug model) loaded SNEDDs, showed that the optimized SNEDDs could properly penetrate toward the posterior segments of the eye especially the retina, posterior parts of the choroid, and sclera. Considering the outstanding results obtained by ocular tissue penetration and low toxicity, prepared SNEDDs, have the potential to be used as a topical administration for treating posterior segment disorders of the eye through an utterly non-invasive route and TCA-loaded SNEDDs could be an alternative for TCA intravitreal and intra conjunctival injections.
A foot-and-mouth disease vaccine is produced from virus of the foot-and-mouth disease which has been cultivated in Frenkel's nutrient solution in the presence of the epithelium of the outer skin from slaughtered pigs.  The culture medium may contain an antibacterial, e.g. a mixture of dihydroxystreptomycin and chloramphenicol.  The temperature of cultivation is 25 DEG  to 40 DEG C. and preferably 37 DEG  C. and the duration of cultivation 20 to 30 hours.  The virus extract obtained is mixed with sterilized and cooled aluminium hydroxide in ratio of 50 : 50.  It is then inactivated with formalin at pH 8.5 to 8.8 for 24 hours at 25 DEG  C. Frenkel's solution is an aqueous solution of amino acids, vitamins and inorganic salts.