Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. In France, the latest estimates put the number of deaths by suicide at 9,000 per year, with 200,000 attempted suicides treated in emergency departments, leading to between 90,000 and 100,000 hospitalisations. Although the number of deaths by suicide has fallen in France (from 11,000 in the 1990s to 9,000 at present), suicide is still a major public health problem (the French rate remains one of the highest in Europe).

It is estimated that almost half of all suicides consult a general practitioner in the month before they commit suicide. Suicide affects young people as much as adults. It has become a major public health problem among adolescents. This dramatic act is often misunderstood, but almost always reflects psychological suffering, exhaustion and resignation. The World Health Organisation (WHO) has declared a state of emergency and is urging each country to develop a comprehensive multisectoral strategy for effective suicide prevention. To this end, suicide risk assessment tools have been developed with a predictive aim. Vigilance and surveillance systems such as "VigilanS " for suicidal people, structures such as crisis centres, and enhanced community support have been put in place. However, diagnosis remains difficult and the risk of recidivism remains the fear of the psychiatrist.

Suicide is about death, about putting an end to one's suffering by aspiring to a definitive appeasement of tensions. It is also a question of existential claim and it is at this level that the question of the meaning of life arises. Indeed, clinical practice very often confronts the psychiatrist, with suicidal subjects, with statements of the type (even if it is not formulated as clearly as the following sentence): "I want to die so as not to suffer any more and I claim the right to put an end to an existence that no longer has any meaning, I choose to finally find peace". How then can we understand that a person gives himself death because he no longer finds a reason to exist? And conversely, that having a reason to live gives a purpose to our existence and can help prevent suicide? It is in this sense that a hypothesis has been put forward over the last few decades, based on the principle that questioning subjects about the vision they have of their existence and the meaning they give to their lives would perhaps help to better understand the psychology of the suicidal person and to prevent them from committing suicide. This reflection, which has its roots in philosophy, has now led to empirical research that has endeavoured to study and take into account, but this time in a quantitative manner and no longer confining itself to philosophical reflection, the question of meaning as a protective factor against suicide: we shall return to this later in the course of this work. Finally, it should be noted that the COVID epidemic has brought the question of meaning and suicide prevention to the forefront, as evidenced by the deleterious impact of the COVID epidemic on adolescents.