anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
As a complex movement, Tai Chi (TC) could be challenging for knee control, and the compensatory changes in TC biomechanics of knee pain patients are unknown. The Brush Knee and Twist Step (BKTS) is a typical TC movement that involves basic leg motion repeated in the whole TC. This pilot study examined electromyography and retro-reflective marker trajectory data to investigate neuromuscular control strategies of the lower extremity during BKTS in TC practitioners with and without knee pain. Twelve experienced TC practitioners with (n = 6) and without knee pain (n = 6) participated. Our results revealed that knee pain practitioners presented muscle imbalance in the vastus medialis-vastus lateralis and vastus lateralis-biceps femoris, and poor alignment of the knee with the toes in TC lunge. Additionally, they adaptively developed rigid coordination strategies, showing higher levels of lower limb muscle co-contraction and activity compared to controls. Training programs for TC practitioners with knee pain should be designed to modify both abnormal muscle synergy patterns and incorrect lunge during TC, which may improve exercise safety.
Veterinary compositions for the treatment of coccidiosis in poultry comprises 4-bromo-41-nitrocarbanilide in admixture with a non-toxic pharmaceutically acceptable diluent or carrier. The compositions may be such as can be admixed with foodstuff or drinking water, or may be in the form of a food composition in which the active ingredient is mixed with an edible vegetable material such as animal or poultry feed urea, corn meal, fermentation residues and distillers' dried grain.  Compositions for admixture contain 1 to 50, and preferably 3 to 20, per cent of the active ingredient.  Food compositions contain 0.005 to 0.05, and preferably 0.01 to 0.03, per cent of the active ingredient.  The active ingredient may also be put up in the form of a tablet or capsule.  Compositions for admixture take the form of (a) powders, (b) aqueous dispersions.  For powders, the carriers are solids such as talc, kaolin, chalk, lactose or urea with or without the further addition of dispersing and/or wetting agents such as the condensation product of cetanol and ethylene oxide, the condensation product of betanaphthalene sulphonic acid and formaldehyde, or a thickening agent such as methyl cellulose. Aqueous dispersions may contain (a) sweetening agents such as lactose, (b) solubilizing agents such as propylene glycol, and (c) dispersing agents such as polyoxyethylene sorbitan monooleate. In the case of foods, the active ingredient may be dissolved in a suitable organic solvent such as acetone, the solution so obtained distributed in the food and the solvent removed by, e.g., drying at 50 DEG  C.
This study consists of a randomized controlled cohort and a long stent observational cohort. The randomized controlled trial is a prospective, multi-center, non-inferior, randomized controlled trial. The control device (RESOLUTE zotarolimus-eluting stent) used in this trial was provided by Medtronic. RESOLUTE zotarolimus-eluting stent has been already approved by China Food and Drug Administration (CFDA) in 2009 and become commercially available in Chinese market. 400 patients enrolled in this trial will be randomly assigned to CRE8 group (n=200) and RESOLUTE group (n=200) in a 1:1 ratio. The long stent observational trial plans to enroll 30 consecutive patients. Patients in the observational cohort will receive the long CRE8 stent with length 38mm.All 430 patients will be required to receive clinical follow-up at 1 month, 6 months, 9 months, 12 months and annually up to 5 years after the procedure, and angiographic follow-up at 9 months after the procedure. The primary endpoint is in-stent LLL at 9 months after the procedure, and the secondary endpoints are device success rate, device-oriented cardiovascular composite endpoint, patient-oriented cardiovascular composite endpoint and stent thrombosis.
Prostatitis is so widespread a disease that affects people from youths to seniors, with approximately a third experiencing a remission of symptoms over a year follow-up. Although the etiology of prostatitis is still not clear, it is mainly thought to be due to infection of bacteria or other microorganisms. Traditional techniques to identify bacteria (e.g. on agar petri plates) are limited in what they can identify. Although HMP (Human Microbiome Project) has turned many mysteries into common sense, little is done on the relationship of bacteria in the prostate for prostatitis. Up to now, there is still no research being done on the microbiome (bacterial species) of the prostate. The objective of this study is to look at the etiology of chronic prostatitis (bacteria or non-bacteria prostatitis), mainly focusing on the effect of bacteria in the prostate. Modern sequencing methods, such as 16s rRNA amplification, cloning and sequencing will be used to evaluate the role of bacteria in prostatitis. The basic idea is to survey the microbes present in expressed prostatic fluid using 16s sequencing to compare healthy men and prostatitis patients in a small cohort to see if there are correlations between microbes found and symptoms.
BACKGROUND: This systematic review aims to synthesize existing research on parental knowledge, attitudes, and barriers to human papillomavirus (HPV) vaccination in the Gulf Cooperation Council (GCC) countries.
METHODS: Following PRISMA guidelines, this systematic review analyzed parental knowledge, attitudes, and barriers to HPV vaccination in 6 GCC countries. A comprehensive search across multiple electronic databases (Embase, Cumulative Index of Nursing and Allied Health Literature, Scopus, Ovid MEDLINE, Web of Science, and PubMed) was conducted, focusing on studies published between January 2010 and December 2023. Inclusion criteria targeted studies in English or Arabic involving parents in GCC countries, excluding non-research publications and those not using survey techniques.
RESULTS: The review included 7 studies from Saudi Arabia, the United Arab Emirates, and Qatar. No study was found in Oman, Bahrain, and Kuwait. The findings highlighted low knowledge and awareness of HPV and the vaccine, with significant variation across studies. According to our review findings, the level of awareness in the 7 studies was found to be low to high. These studies collectively illustrate a range of awareness levels, from as low as 11% awareness of the HPV-cervical cancer link to as high as 68% general awareness of HPV. Attitudes towards vaccination were poor in Saudi Arabia but more positive in the United Arab Emirates and Qatar. Major barriers included safety concerns, lack of information, and cultural beliefs.
CONCLUSION: Despite moderate awareness in some GCC countries, substantial knowledge gaps and vaccine hesitancy persist. Targeted educational campaigns, effective communication strategies, and involvement of community leaders are essential to improve HPV vaccination uptake.
The invention relates to an enteromorpha prolifera-containing moisturizing oxidation-resistant mask. Liquid essence mainly comprises grape seed oil, enteromorpha prolifera polysaccharide, bitter orange flower essential oil, cypress essential oil and natural citric acid, and a mask prepared from enteromorpha prolifera fibers is immersed into the compound liquid essence so that the enteromorpha prolifera-containing moisturizing oxidation-resistant mask is obtained. The invention provides the purely ecological oxidation-resistant mask. The mask base is prepared from enteromorpha prolifera fibers, natural grape seed oil is used as base oil of the liquid essence, an antiseptic component is a natural antiseptic extracted from marine organism, and natural citric acid is used as a pH adjustment agent and is used for adjusting a pH value of the mask so that the mask is weakly acidic and is suitable for skin. The enteromorpha prolifera-containing moisturizing oxidation-resistant mask has an all natural bio-formula, does not contain any chemical components, has the characteristics of high-efficiency moisturizing and oxidation resistance, wrinkle and aging resistance, allergy resistance and skin regeneration, skin brightening, no toxicity, no irritation and environmental friendliness. Compared with the traditional smear-type mask, the enteromorpha prolifera-containing moisturizing oxidation-resistant mask can be used conveniently and can be cleaned easily.
Drug delivery devices, sealing members for containers housed within such drug delivery devices, and related methods of assembly are disclosed. The drug delivery device may include a housing, a container disposed in the housing and having an interior volume, a drug disposed in the interior volume, and a septum. The container may have an opening formed in an end surface and which communicates with the interior volume. The septum may include a proximal end inserted through the opening into the interior volume of the container. Additionally, the septum may include a distal end having a flange disposed outwardly of the proximal end and contacting the end surface of the container. At least an end portion of the flange may be made of a material that is permeable to a gaseous sterilizing agent.
Adolescents in the intervention group were divided into 11 smaller groups, each containing five participants to explain the application. The researcher provided a brief presentation about the health benefits and appropriate serving sizes of F\&Vs and explained how to use the smartphone application. An instructional brochure was provided in Arabic to all adolescents in the intervention group. The research team was available to assist participants at any time during the study period. After choosing six goals (three for fruit and three for vegetables), the participants were required to mark the goal that they chose daily and were requested to adhere to their chosen goals until the end of the study. The intervention period was 6 weeks.
Long term nucleoside/nucleotide analogues (NAs) treatment is required in the treatment of chronic hepatitis B (CHB). According to current treatment guidelines from APASL 2015, NAs treatment can be stopped if, after HBsAg loss following either anti-HBs seroconversion or at least 12 months of a post-HBsAg clearance consolidation period or after treatment for at least 2 years with undetectable HBV DNA documented on three separate occasions, 6 months apart. In Taiwan, the National Health Insurance system only reimburse 3 years NAs for CHB patients. Previous study from Jeng et al. suggested that the 1-year rate of clinical relapse (HBV DNA\>2,000 IU/mL plus ALT\>2X ULN) after cessation of entecavir(ETV) therapy by APASL stopping rule (treatment \>2 years, HBV DNA undetectable \>1 year) in HBeAg-negative chronic hepatitis B(CHB) patients was 45%, of which 25.6% occurred within 6 months. Recently, another study from Jeng et al showed that 34 HBeAg(-) patients who stopped TDF therapy by APASL stopping rule were followed-up every 1-3 months for \>6 months. Of these 34 patients, mean age was 51.8 years, 82.4% were males and 14(41.2%) were cirrhotic. The 1-year cumulative clinical relapse rate was 46%, of which 93.3% occurred within 6 months, and 13.3% developed decompensation. Clinical relapse occurred much earlier and tended to be more severe after cessation of TDF than ETV. The follow-up interval and intensity would be different between ETV and TDF after discontinuation of therapy. Whether switch therapy from TDF to ETV can modify the pattern of relapse is interesting but unclear. Our hypothesis is that entecavir consolidation on post-TDF treatment patients reduce and delay the clinical relapse effectively. Hence in this proof of concept study we would like to evaluate the effect of 6 months and 12 months of entecavir consolidation on post-TDF treatment durability.
<P>PROBLEM TO BE SOLVED: To display only an object related to a report at a key image in attaching a medical image including an object as a key image to a radiographic report.  <P>SOLUTION: A medical image includes a measurement result object indicating a distance between two points. In writing an opinion in a radiographic report, when a measurement result object on a medical image is selected, the measurement value is inserted as an opinion. When the measurement value is inserted, object specification information for associating the measurement result object with an opinion is created. When a medical image is attached as a key image to a radiographic report, whether or not the measurement result object is associated with an opinion is decided based on the object specification information. Then, only the object for a key image corresponding to the measurement result object corresponding to the opinion is displayed on the key image.  <P>COPYRIGHT: (C)2009,JPO&INPIT
The present invention provides a technique for more rapidly and efficiently screening target cells that produce a target substance that specifically binds to a desired cell membrane protein, the technique including: a substrate 1 having a plurality of pores 2 is provided. First cells 3 expressing a target cell membrane protein on the cell surface are attached to each microwell 2. 1 or 2 second cells 5 as candidates of target cells are introduced into each microwell 2, and the target substance 6 secreted from the second cells 5 is brought into contact with the first cells 3 while being allowed to coexist with the first cells 3 in the microwells 2. A microwell 2 is selected that contains a first cell 3 to which a substance of interest 6 is bound. From the selected microwells 2, the second cells 5 as target cells are recovered. The target substance 6 may be an antibody. A marker substance 7 may also be added for visualization.
This study is a single centre, prospective, physiologic study in extubated patients (n = 110) to assess the contractility of the diaphragm, intercostal, and sternocleidomastoid muscles. The purpose is to determine whether employing ultrasounds early after extubation is a useful diagnostic tool to identify patients who may be at risk of extubation failure and/or intensive care unit (ICU) re-admission. The study will be performed in the Medical-Surgical ICU of St. Michael's Hospital.

Once the clinical team has decided to extubate the patient, the research team will approach the patient for consent (if capable) or the patient's substitute decision maker. Demographic information will be extracted from the medical chart and entered into the study case report form (CRF). Ultrasounds of the diaphragm, intercostal, and sternocleidomastoid muscles will be performed within 2 hours of extubation and repeated within 24 hours of extubation (if feasible). The following physiological and biological variables will be collected before and after the spontaneous breathing trial (SBT): mode of ventilation and settings, Arterial Blood Gas (ABG) results, heart rate, arterial blood pressure, peripheral capillary oxygen saturation (SpO2), respiratory rate, Glasgow Coma Score (GCS), temperature, fluid balance in the last 24 hours, Sequential Organ Failure Assessment (SOFA) score, and rapid shallow breathing index (RSBI). At the time of the ultrasound measurements, the following physiological variables will be collected: heart rate, arterial blood pressure, SpO2, respiratory rate, Glasgow Coma Score (GCS), cough, Intensive Care Delirium Screening Checklist (ICDSC), ambient air, oxygenation, use of non-invasive ventilation (NIV), level of dyspnea, level of comfort, nasal flaring, Medical Research Council (MRC) score, and the Respiratory Intensive Care Observation Scale (RICOS). Outcome data will be recorded including: extubation failure, use of NIV and/or high-flow nasal oxygen cannula post extubation, re-intubation, ICU discharge/re-admission status, and tracheostomy. A 7-day follow-up after ICU discharge will signify completion of the study.
INTRODUCTION: The prevalence of alpha-1 antitrypsin deficiency (AATD) in Macaronesia (i.e., Azores, Madeira, Canary Islands, and Cape Verde archipelagos) is poorly known. Our goal was to update it by selecting the most reliable available articles.
METHOD: Literature search using MEDLINE, Embase (via Ovid), and Google Scholar, until December 2023, for studies on prevalence of AATD in the general population and in screenings, published in peer-reviewed journals.
RESULTS: Three studies carried out in the general population of Madeira, La Palma, and Cape Verde, and three screenings carried out in La Palma (2) and Gran Canaria (1) were selected. The frequencies of PI*S in the general population showed an ascending gradient, from South to North, with values (per thousand) of 35 in Cape Verde, 82 in La Palma, and 180 in Madeira. The PI*Z frequencies showed this same gradient, with values of 2 × 1,000 in Cape Verde, 21 in La Palma, and 25 in Madeira. Screenings detected high percentages of defective alleles, including several rare and null alleles, some unique to these islands.
CONCLUSION: The frequencies of PI*S and PI*Z in Madeira are comparable to the highest in the world. Those of the Canary Islands are similar to those of the peninsular population of Spain, and contrast with the low rates of Cape Verde. Screenings detected high numbers of deficient alleles. These results support the systematic investigation of AATD in clinically suspected patients and in relatives of index cases, to reduce underdiagnosis and apply early preventive and therapeutic measures in those affected.
New variety of salt containing at least 95 wt.% of sodium chloride and having wt. loss on heating to 500 deg C for 24 hours less than 1200 mg/kg, is obtained by heating sodium chloride powder to 380-480 deg C for 20-90 minutes. The method of determining water content of salt from wt. loss under heating to above 450 deg C, for 24 hours, is also new.  Independent claims are also included for 1) use of salt as claimed for preparation of compositions for therapeutic application; 2) process of production of salt as claimed, comprising subjecting sodium chloride powder to drying at temperature higher than 300 deg C and lower than 600 deg C (preferably 380-480 deg C, for 20-90 minutes; and 3) method of determining water content in sample of salt, based on measuring wt. loss on drying, with the latter conducted at temperature above 450 deg C, for at least 24 hours.
CIPRODEX® OTIC SHOULD BE SHAKEN WELL IMMEDIATELY BEFORE USE

CIPRODEX® Otic contains 3 mg (3000 ug/mL) ciprofloxacin and 1 mg/mL dexamethasone.

Acute Otitis Media in pediatric patients with tympanostomy tubes: The recommended dosage regimen for the treatment of acute otitis media in pediatric patients (age 6 months and older) through tympanostomy tubes is: 

Four drops (0.14 mL, 0.42 mg ciprofloxacin, 0.14 mg dexamethasone) instilled into the affected ear twice daily for seven days. The suspension should be warmed by holding the bottle in the hand for one or two minutes to avoid dizziness, which may result from the instillation of a cold suspension. The patient should lie with the affected ear upward, and then the drops should be instilled. The tragus should then be pumped 5 times by pushing inward to facilitate penetration of the drops into the middle ear. This position should be maintained for 60 seconds. Repeat, if necessary, for the opposite ear. Discard unused portion after therapy is completed.

Acute Otitis Externa: The recommended dosage regimen for the treatment of acute otitis externa is: For patients (age 6 months and older): Four drops (0.14 mL, 0.42 mg ciprofloxacin, 0.14 mg dexamethasone) instilled into the affected ear twice daily for seven days. The suspension should be warmed by holding the bottle in the hand for one or two minutes to avoid dizziness, which may result from the instillation of a cold suspension. The patient should lie with the affected ear upward, and then the drops should be instilled. This position should be maintained for 60 seconds to facilitate penetration of the drops into the ear canal. Repeat, if necessary, for the opposite ear. Discard unused portion after therapy is completed.
The current guidelines for suspected choledocholithiasis are aimed to reduce the risk of patient receiving diagnostic ERCP and reduce the risk of post ERCP adverse events. In this process there is apparent increase in number of patients in the intermediate likelihood group requiring EUS or MRCP. This can increase the health care utilization and cost of care for intermediate likelihood patients. The field of artificial intelligence in clinical medicine is evolving rapidly. The use of artificial intelligence based machine learning model is not adequately studied for prediction of choledocholithiasis. Machine learning predictive model can help in stratifying heterogenous intermediate likelihood group to reduce need for EUS or MRCP in selected subgroup of patients.
Procedure: A modified microsurgical tunnel technique by Zuhr et al. (2007). Initial sulcular incisions with a microsurgical blade are followed by a split-thickness buccal flap preparations using the tunneling knives. The preparation is extended into the mucosal tissue to gain sufficient flap mobility. The papillary regions are detached in their buccal aspects with the periosteum. The root surfaces are applied with cross-linked hyaluronic acid. The graft is inserted into the tunnel and stabilized with absorbable suspensory sutures. The buccal flap is advanced coronally and stabilized with non-absorbable suspensory sutures.
<P>PROBLEM TO BE SOLVED: To provide a face image utilization system, and the like that utilizes existing imaging unit for authentication photograph.  <P>SOLUTION: An imaging unit 3 for authentication photograph requests a center server 7 to collate a photographer ID and a password of an imaging object person 5 to be imaged, obtained by a photographer information acquisition means 15. When imaging is permitted, the imaging unit 3 images the facial image of the imaging subject person 5 by an imaging means 12. The imaging unit 3 for authentication photograph converts the imaged face image into a specified data format, encrypts and transmits to the center server 7, together with the photographer ID and the password having added check digits. After deciding on the received data contents, the center server 7 issues an acceptance number and stores the face image data. The facial image data may be divided into two or more, and stored in a sub-center 1 8 and a sub-center 2 9. The imaging unit 3 for authentication photograph prints out the acceptance number which is received in the center server 7, on a receipt 20.  <P>COPYRIGHT: (C)2009,JPO&INPIT
1394981 Incinerators NICHOLS ENG & RESEARCH CORP 1 Oct 1973 [6 Oct 1972] 45695/73 Heading F4B An incinerator for sewage scum has a lower tank portion 12. an ignition chamber 14 above the tank and in communication with it, and an upper combustion chamber 16 communicating with the ignition chamber 14, the tank 12 having an inlet 18 for a continuous flow of sewage consisting of floatable solids in water and an outlet controlling the liquid level in the tank, ignition burners 50 and air nozzles 52, 62 in the chamber 14 and nozzles 78 for combustion air in chamber 16, the products of combustion being discharged through a gas scrubber with a lower outlet for solid materials and an upper outlet for exhaust gases. As the sewage flows through the tank oleaginous solids rise to the surface and, after twelve or more hours, sufficient has accumulated to be burned. The floated scum is agitated by fingers 42 rotating with shaft 44. The roof of chamber 14 is a shallow dome having a passage 72 in the middle. A baffle 74 over the upper end of passage 72 causes the combustion gases from chamber 14 to enter chamber 16 radially and mix with combustion air from tangentiallydirected jets 78. Fully burnt gases leave chamber 16 via passage 86 and are drawn downwardly through a duct with a butterfly control valve and a cooler to a blower which forces the gases through a water scrubber to a chimney.