anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
PURPOSE: The aim of this study was to use the National Ambulatory Medical Care Survey database to assess MRI utilization in patients 50 years and older with atraumatic hip or knee pain.
METHODS: National Ambulatory Medical Care Survey weighted survey data (2007-2019) were obtained for ambulatory visits in patients 50 years and older with atraumatic hip or knee pain. The outcome variable was MRI ordering status, and analyzed characteristics included patient age, race/ethnicity, payer, physician specialty, metropolitan statistical area, and a coexistent radiography order. Multivariable logistic regressions were conducted to assess the association between MRI ordering status and the analyzed patient characteristics. All tests were two sided, and P values ≤.05 were considered to indicate statistical significance.
RESULTS: In total, 88,978,804 knee pain and 28,675,725 hip pain patient visits (survey weighted) were analyzed, with 4,690,943 (5.3%) and 2,023,226 (7.1%) having knee or hip MRI orders, respectively. Overall, 2,454,433 knee pain visits (2.8%) and 575,155 hip pain visits (2.0%) had orders for both MRI and radiographs. Black patients (P = .03) and patients 80 years and older (P = .04) were less likely to have knee MRI ordered, whereas uninsured patients were less likely to have hip MRI ordered (P = .01). Patients with hip pain were more likely to have hip MRI ordered if seen by a surgical subspecialist (P = .01).
CONCLUSIONS: A low proportion of MRI examinations were ordered for visits in patients 50 years and older with atraumatic hip or knee pain. Groups with lower health care access were less likely to have an MRI order, highlighting known disparities in health care equity.
Disclosed are articles useful in cleansing, and particularly wet-like cleansing wipes, which are dry until used, where fluid is released from the article. These articles comprise: a) a carrier comprising a cellulosic fibrous structure having at least a first region of relatively high basis weight that comprises an essentially continuous network and a second region of a plurality of mutually discrete regions of relatively low basis weight which are circumscribed by the high basis weight first region; and b) an emulsion applied to the carrier, where the emulsion provides fluid for cleaning when shear forces are applied to the article. The first and second regions of the cellulosic fibrous structure are disposed in a nonrandom, repeating pattern. The articles offer a number of significant advantages over prior cleaning products when in the form of wet-like cleansing wipes such as those used for cleaning of hard surfaces (e.g., floors, countertops, sinks, bathtubs, toilets, and the like). The inclusion of low basis weight regions avoids substantial fluid retention by the cellulosic fibrous substrate, which allows fluid delivery to the surface being cleaned. The articles can be used in many applications requiring the delivery of polar materials, in particular water and water-soluble or dispersible actives. These include toilet tissue, wipes for personal cleansing, such as baby wipes, as well as those for the delivery of water-soluble or dispersible antimicrobials or pharmaceutical actives.
Laparoscopic treatment for endometrioma Surgicel® will use Hemostatic matrix (Surgicel® Original Absorbable Hemostat, Ethicon, USA). Transvaginal ultrasound for antral follicle count and blood collection will be performed in this group of patients before surgery, 1, 3 and 6 months after the procedure to dose AMH level, FSH level and to count the number of antral follicle.
Tracheal intubation performed with a video laryngoscope with Miller-blade or Macintosh-blade size No. 0 or No. 1 without apneic oxygenation.
Sugar-sweetened beverage (SSB) consumption is strongly associated with obesity. Autonomous motivation and self-efficacy, key concepts of self-determination theory, may influence SSB consumption. Low-income mothers of young children experience disproportionate rates of obesity. Whether autonomous motivation and self-efficacy are associated with SSB consumption in low-income mothers of young children is unknown. This exploratory secondary data analysis explored whether autonomous motivation or self-efficacy were associated with SBB consumption using data from a lifestyle intervention for low-income, overweight or obese mothers with young children. Participants (N = 311) completed surveys assessing autonomous motivation, self-efficacy, and SSB consumption at baseline, after the 16-week intervention, and at 3-month follow-up. Using baseline data, we performed linear regression models to explore associations of self-efficacy and autonomous motivation with SSB consumption. We also performed mixed effects models to explore whether autonomous motivation or self-efficacy were associated with SSB consumption over time. At baseline, a one-point increase in autonomous motivation and self-efficacy were associated with 4.36 (p < 0.001) and 6.43 (p = 0.025) fewer ounces of SSB consumption per day, respectively. In longitudinal models, SSB consumption decreased over time. Change in SSB consumption was associated with self-efficacy (B = -4.88; p = 0.015) and autonomous motivation (B = -2.29; p = 0.008). Our findings suggest self-efficacy and autonomous motivation may influence SSB consumption among mothers of young children with overweight and obesity. Further investigation should explore if self-efficacy and autonomous motivation have long-term effects on SSB consumption.
Participants view an educational video instructing them on how to manually check their pulse for irregularities. Participants will be instructed to check their pulse for 30 seconds twice daily for 2 weeks.
This outpatient study will be conducted in 3 phases. Phase 1: Patients meeting entry criteria will be treated with open label aripiprazole (APZ) in order to achieve therapeutic doses of this agent. The primary objective of this phase is to stabilize the patient's mood prior to randomization in phase 2. Adjunctive treatment of attention-deficit hyperactivity disorder (ADHD) will be permitted during this phase after week 6 of phase 1. In order to be entered into Phase 2, patients must be clinically stable based on a priori criteria (see below). The maximum allowable duration of Phase 1 will be 16 weeks. Only patients who have achieved syndromal remission (not just improvement) will be eligible for randomization into phase 2.

Phase 2: Patients that achieve syndromal remission during Phase 1 will be randomized in a double-blind fashion to receive either ongoing APZ therapy or placebo therapy during Phase 2. Patients who are receiving co-administration of ADHD pharmacotherapy may continue with this during Phase 2. Patients will have an equal chance of being assigned to each of the 2 treatment arms. Randomization strata will be based on whether or not the subject is receiving ADHD pharmacotherapy and whether or not the subject is suffering from Bipolar 1 or 2 disorders. The maximum length of time a patient may remain in phase 2 will be 72 weeks. Youths who develop a major depressive episode, a manic, or mixed episode, or youths for whom continued enrollment in this phase of study is contraindicated (as determined by the patient, guardian, research team or study physician), will be withdrawn from phase 2. Youths who withdraw from phase 2 may enter Phase 3. Reason for removal from phase 2 will be documented. For those youths who successfully complete 72 weeks of participation in phase 2, trial participation will be ended. Those patients who complete phase 2 will receive follow up clinical care either at University Hospitals-Cleveland (UHC) or with a community-based physician.

Phase 3: For youths who are withdrawn during phase 2, 8-weeks of open-label treatment with APZ will be available
Participants will be on waiting list for 16±2 weeks. After waiting list participants are offered the CONSENT program including therapy delivered twice a week (total time 12 ± 2 weeks), with measurement after for 16±2 weeks.
Background: Vitiligo is characterized by a depigmentation acquired with partial or total loss of melanocytes from the epidermis, causing great psychosocial impact. Several therapeutic modalities have been proposed for its treatment and surgical treatments have been shown to be promising, especially in recalcitrant cases. The technique of epidermal rasping grafting, a variant of the punch micrografts technique, shows high repigmentation rates and does not require high cost technology. Objective: The objective of this project is to perform a comparative study for the surgical treatment of vitiligo, in which the same patient (N = 10) will receive, in symmetrical acrylic areas, only dermabrasion with a micro needling of 0.25 mm or dermabrasion using micro needling followed of the cell suspension application (melanocytes and uncultured keratinocytes). Methodology: In the donor area (scalp) the healthy tissue will be removed. This tissue will be placed in a sterile container with physiological saline and fragmented with delicate scissors for about 20 minutes until homogeneous consistency of the material is obtained. After the enzymatic digestion of epidermal cells of the dermis, it will isolate melanocytes and keratinocytes that will be placed in the recipient area. After 15 days of the surgical procedure, patients will start the phototherapy UVB-NB sessions (twice a week). The patients will be evaluated about the pain during the procedure, the improvement of injuries of vitiligo and the vitiligo-specific quality-of-life instrument (VitiQoL Vitqol Index) will be applied after and before the treatment. Conclusion: The technique of grafting by epidermal scrap shows high rates of repigmentation and does not require high cost technology, which motivated us, in this study, corroborating the literature and helping to disseminate this technique.
Laboring women receiving the Dural Puncture Epidural (DPE) Technique with dose of Bupivacaine 0.25% diluted to 20 mL with isotonic sterile 0.9% saline. The first subject in the DPE group will receive an initial dose of bupivacaine 25 mg, with an endpoint being the achievement of an NRS \< 3 at 30 min. Subsequent patients are administered bupivacaine doses determined by the response of the previous subject, as per the biased coin method. The subsequent up and down interval doses are bupivacaine 2.5 mg (1 mL) increments, with an anticipated dose range from 20 mg to 40 mg.
<P>PROBLEM TO BE SOLVED: To provide a bofutusyosan-blended preparation reduced with an unpleasant flavor peculiar to the bofutusyosan, a method for improving the flavor of the bofutusyosan and a flavor-improving agent.  <P>SOLUTION: This bofutusyosan-blended preparation comprises the bofutusyosan and insoluble edible fibers. The method for improving the flavor of the bofutusyosan is to use the bofutusyosan with the insoluble edible fibers jointly. The flavor-improving agent of the bofutusyosan is to contain the insoluble edible fibers as an active ingredient. The insoluble edible fibers are at least one selected from the group consisting of cellulose, agar, chitosan, chitin, hemicellulose, lignin and glucan.  <P>COPYRIGHT: (C)2010,JPO&INPIT
PURPOSE:The titled plaster base capable of keeping a blended drug stably without decomposing it, obtained by adding dried rhizome of Paeonia suffruticosa ANDREUS (Paeonia moutan SIMS) and dried root of Paeonia lactiflora PALLAS var. trichocarpa (Bunge) STERN (Paeonia albiflora PALLAS var. trichocarpa BUNGE) to a rubber-like adherent substance. CONSTITUTION:A rubber-like adherent substance of natural rubber or synthetic rubber or their mixture is blended with dried rhizome of Paeonia suffruticosa ANDREUS (Paeonia moutan SIMS) and dried root of Paeonia lactiflora PALLAS var. trichocarpa (Bunge) STERN (Paeonia albiflora PALLAS var. trichocarpa BUNGE) (each of them is used even in the form of extracted or dried extract). Amounts of both the substances are 0.03-2wt% based on the adherent substance, respectively, and preferably 0.005-2wt% in the case of extract. This plaster base is especially effective for drugs consisting of phenolic hydroxyl group-containing compounds (e.g., salicyclic acid derivatives) or amine compounds (e.g., ethanolamine antihistamines) which reduce their contents extremely in a plaster base consisting of an existing adherent substance.
A compound represented by the formula (I) (wherein X and X’ are the same or different and each represents hydrogen, etc.; R1 and R2 are the same or different and each represents hydrogen, etc.; R3 represents an optionally substituted hydrocarbon group, etc.; R4 represents hydrogen, etc.; Y and Ya are the same or different and each represents a bond or a spacer having a C1-8 main chain; and Z and Za are the same or different and each represents hydrogen, etc.), a salt of the compound, or a prodrug of either. They have inhibitory activity against somatostatin receptor binding and are effective in the prevention of and treatments for, e.g., diseases in which somatostatin participates.
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a group of chronic interstitial pulmonary diseases characterized by myofibroblast proliferation and extracellular matrix (ECM) deposition. However, current treatments are not satisfactory. Therefore, more effective therapies need to be explored. Cepharanthine (CEP) is a naturally occurring alkaloid that has recently been reported to have multiple pharmacological effects, particularly in chronic inflammation.
METHODS: For in vivo experiments, first, a pulmonary fibrosis murine model was generated via tracheal injection of bleomycin (BLM). Second, the clinical manifestations and histopathological changes of the mice were used to verify that treatment with CEP might significantly reduce BLM-induced fibrosis. Furthermore, flow cytometric analysis was used to analyze the changes in the number of M2 macrophages in the lung tissues before and after treatment with CEP to explore the relationship between macrophage M2 polarization and pulmonary fibrosis. In vitro, we constructed two co-culture systems (THP-1 and MRC5 cells, RAW264.7 and NIH 3T3 cells), and measured the expression of fibrosis-related proteins to explore whether CEP could reduce pulmonary fibrosis by regulating macrophage M2 polarization and fibroblast activation.
RESULTS: The results showed that the intranasal treatment of CEP significantly attenuated the symptoms of pulmonary fibrosis induced by BLM in a murine model. Our findings also indicated that CEP treatment markedly reduced the expression of fibrosis markers, including TGF-β1, collagen I, fibronectin and α-SMA, in the mouse lung. Furthermore, in vitro studies demonstrated that CEP attenuated pulmonary fibrosis by inhibiting fibroblast activation through modulating macrophage M2 polarization and reducing TGF-β1 expression.
CONCLUSIONS: This study demonstrated the potential and efficacy of CEP in the treatment of pulmonary fibrosis. In particular, this study revealed a novel mechanism of CEP in inhibiting fibroblast activation by regulating macrophage M2 polarization and reducing the expression of fibrosis-associated factors. Our findings open a new direction for future research into the treatment of pulmonary fibrosis.
Pharmaceutical compositions containing an effective amount of a ligand for GPR109 to decrease intracellular cAMP levels of a subject in combination with an effective amount of a DNA methyl transferase inhibito to reduce or inhibit downregulation of GPR109 in the intestinal epithelial cells of the subject relative to a control are provided. It has been discovered that ligands for GPR109 can be used to treat one or more symptoms of cancer, inflammatory disorders, and diarrhea. Representative CPR109 ligands include, but are not limited to butyrate, β-hydroxybutyrate, nicotinic acid, acifran, and octanoate. Suitable DNA methyl transferase inhibitors include 5-azacytidine, 5-aza-2′-deoxytidine, 1-β-D-arabinfarnosyl-5-azacytosine and dihydro-5-azacytidine. Typically, the compositions are formulated to achieve a GPR109 ligand serum blood level of about 1 to about 1000 μM. The compositions are useful for the treatment of one or more symptoms of cancer. Preferred cancers that can be treated using the disclosed compositions include, but are not limited to colon cancer, breast cancer and leukemia. Methods for treating cancer, inflammatory disorders, and diarrhea are also provided.
Some patients accidentally taking 600 mg twice daily have reported increased nervous system symptoms. One patient experienced involuntary muscle contractions.

Treatment of overdose with SUSTIVA should consist of general supportive measures, including monitoring of vital signs and observation of the patient’s clinical status. Administration of activated charcoal may be used to aid removal of unabsorbed drug. There is no specific antidote for overdose with SUSTIVA. Since efavirenz is highly protein bound, dialysis is unlikely to significantly remove the drug from blood.
The patients in this group will listen to the "Rast Makam", which was created as a result of research conducted by the Turkish Music Research and Promotion Group (TÜMATA) and provides individuals with comfort and inner peace. The patients scheduled to receive chemotherapy for the first time, will be allowed to listen to music for at least one hour during chemotherapy with over-ear headphones (Sennheiser HD280) and an MP3 player. Anxiety and satisfaction levels of the patients will be recorded before and after the music application.
A probe apparatus for self-administered treatment of prostatitis has a pair of opposing handle bars (12) symmetrical to each other having handle grip ends (1O, 11) and connected to a center housing (4) along a common axis, and a probe (1) connected to a front side of the center housing and extending to a probe tip (3). The center housing has a vibrator motor which is mechanically coupled to the probe tip, and is actuated by a switch on one of the handle grip ends. The probe has a swivelable tip actuated by a pair of swivel actuators (6, 7) provided on the handle grip ends. The probe tip has an off-center bulbous or ovoid shape for effecting a sweeping movement over the prostate when a swivel actuator is actuated. The probe and the handle grip ends have approximately the same length and extend in the same direction for more precise manipulation by the patient. The handle bars are connected to the center housing by twist-lock disconnectors (14) to be detachable for storage or packing. The probe apparatus is employed by inserting the probe into the rectum from the rear of the patient, and positioning the probe tip adjacent the colon walls proximate the prostate while manipulating the handle grip ends on each side of the patient. It is employed with the patient in a standing, bent over position, and a mirror is placed on the floor between the patient's feet to provide visual confirmation of the position of the probe. The probe apparatus is effective for prostatitic drainage by manipulating the swivel actuators to sweep over the surface areas of the prostate toward the prostate center in order to drain fluid from the prostate gland and ducts.
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a high burden both for the patient and society. Outcomes for the individuals living with RA have been improved and the majority of RA patients are now in remission or low disease activity status. RA patients continue to be followed up by pre-scheduled visits, which may compromise accessibility for the sickest and thus, quality of care. The introduction of patient-initiated follow-up leads to a reduction in the use of outpatient clinic services without compromising outcomes. Self-monitoring and remote patient monitoring are facilitated by electronic innovative health tools. Among RA patients with low disease activity or remission, a Patient-Reported Outcome-based telehealth follow-up for tight control of disease activity in RA can achieve similar disease control as conventional outpatient follow-up and is likely to reduce the costs. Thus, the main objective of the present project is to test the effect of a customized PRO-based telehealth follow-up compared to a conventional prescheduled outpatient follow-up to monitor disease activity and expenses associated with the follow-up in Norwegian RA patients.
Using purposive sampling method, 84 college students with irritable bowel syndrome (IBS) accompanied by a sense of shame who met the inclusion and exclusion criteria from June 2023 to January 2024 in a comprehensive university in Yangzhou City were selected for the study. Using the method of random grouping, the patients who met the inclusion and exclusion criteria were numbered and randomly divided into the control group and the intervention group by computer random number procedure. Because individual patients fell out during the study, the final sample size for inclusion in the study was 80 cases, with 40 cases in each group. The control group was given conventional health education on irritable bowel syndrome, and the intervention group was given a 6-week acceptance and commitment therapy-based intervention programme for college students with irritable bowel syndrome based on stigma, with a 6-week intervention period and a 3-month follow-up period. The ANOVA of repeated measures data was used to analyse the trends in the Stigma, Psychological flexibility (PF), Self-acceptance (SA) and Quality of Life (QOL) score trends over time to assess the effects of the intervention. A single-blind method was used in this study, and only the outcomes assessor was blinded.
The patient was placed supine on a stretcher and the application will take place with the Chattanooga device, with the laser diode cluster probe from the same manufacturer consisting of five diodes 850 nm and power output of 200 mW. Six points in quadriceps and four points in gastrocnemius, were irradiated, bilaterally, by 30 seconds.
Medical image acquisition using sequence prediction for deep learning. Automated sequence prediction is provided for medical imaging sessions that include a self-assessment mechanism. An initial scout sequence is performed on the patient (11) or subject. The initial scout sequence is validated. A thumbnail acquisition scheme (45) is performed. The thumbnail acquisition scheme (45) is validated. Additional sequences are performed. The sequence may also be configured based on analysis of previous scans using deep learning based reasoning to select the next appropriate settings and procedures.
The invention discloses liver-protecting health-care rice wine which is prepared from the following raw materials in parts by weight: 2-3 parts of cordyceps sinensis, 2-4 parts of wolfberry, 1-2 parts of codonopsis pilosula, 3-5 parts of angelica sinensis, 2-3 parts of schisandra chinensis, 3-5 parts of astragalus membranaceus, 1-3 parts of liquorice, 2-6 parts of lucid ganoderma, 1-4 parts of rheum officinale, 2-4 parts of lithospermum, 80-100 parts of sticky rice, 5-10 parts of honey and 2-5 parts of distiller yeast. The liver-protecting health-care rice wine disclosed by the invention is prepared by fermentation of sticky rice. The sticky rice has the main functions of warmly invigorating spleen and stomach. By adding the liver-protecting health-care traditional Chinese medicine components, the wine has a remarkable health-care function on liver nourishing and protection. The wine which is drunk for a long time plays a role of protecting liver, thereby guaranteeing the physical health of people. Meanwhile, the rice wine disclosed by the invention is mellow and pure in taste, good in curative effect, free of side effects and free of side effects after being eaten for a long time.