anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
Anatomy is a foundation for veterinary medical education, yet its teaching has traditionally posed an academic challenge to students. Anatomy is a three-dimensional (3D) subject that students are often expected to learn using one- or two-dimensional learning resources. Visualization of structures and the transfer of images to animal specimens can impede knowledge acquisition and student confidence. As a response to the COVID-19 pandemic, the first-year anatomy course (Anatomy I) at The Ohio State University College of Veterinary Medicine was delivered virtually in Autumn 2020. Instructors were challenged to create equivalent learning experiences without face-to-face interaction and cadaveric access. Fortunately, multimedia dissection videos were in production and supplemented students' learning of anatomic structures and dissection techniques. Videos included complete narration, explanations, diagrams, labels, and self-check opportunities. To evaluate the perceived effectiveness of the videos on student learning, the Anatomy I teaching team surveyed all first-year veterinary students following the course. Of the 104 students (64%) who completed the survey, 101 (97%) agreed or strongly agreed that the videos helped solidify their anatomy knowledge, skills, and understanding. The most helpful video characteristics included the demonstration of dissection techniques on a cadaver and the visualization of structures on 3D specimens. Students also appreciated the ability to review content at their own pace/convenience, a feature inherent to recorded (asynchronous) video-based instruction. These data suggest that video-based instruction may effectively supplement students' learning of veterinary anatomy and improve the transfer of knowledge, particularly when other forms of direct instruction are inaccessible.
The present invention provides a composition and method for preparing a customized personal care product. The composition comprising a base composition and at least one additive compositions. The base composition is at least one or combination of organic or inorganic ingredients and organic origin ingredients, and the additive compositions include at least one hair care based additive compositions. at least one customized additive of predetermined composition from an ampoule is added to the base composition. The base composition and at least one customized additive compositions are mixed to form a customized personal care composition. The personal care product could be a health care product, beauty product, face serum product, body lotion product, hair care product, or any other product.
BACKGROUND: Intestinal obstruction represents a severe intestinal disease associated with higher mortality rates. However, the determinants of mortality in patients with intestinal obstruction remain inadequately understood. This study sought to elucidate the potential risk factors associated with mortality in the context of intestinal obstruction during the COVID-19 pandemic.
METHODS: A retrospective analysis was performed on a cohort of 227 patients diagnosed with intestinal obstruction at the First Hospital of Hebei Medical University, spanning the period from September 7, 2022, to January 7, 2023. The primary endpoint of the study was mortality within four weeks following discharge. Univariate and multivariable logistic regression models were utilized to evaluate the risk factors associated with mortality outcomes.
RESULTS: A cohort of 227 patients diagnosed with intestinal obstruction (median age, 59.02 years [IQR, 48.95-70.85 years]) was included in our study. Malignant bowel obstruction (MBO) and COVID-19 were identified as independent risk factors for mortality among these patients. Notably, the mortality rate increased significantly to 38.46% when MBO was concomitant with COVID-19. Furthermore, postoperative pulmonary complications (PPC) (OR, 54.21 [death]; 95% CI, 3.17-926.31), gastric cancer (OR, 9.71 [death]; 95% CI, 1.38-68.18), VTE (Caprini Score ≥ 5) (OR, 7.64 [death]; 95% CI, 1.37-42.51), and COVID-19 (OR, 5.72 [death]; 95% CI, 1.01-32.29) were all determined to be independent risk factors for postoperative mortality. Additionally, gastric cancer could have emerged as one of the most severe risk factors for mortality in individuals with intestinal obstruction within the cohort of cancer patients, of which gastric cancer exhibited higher mortality rates compared to individuals with other forms of cancer.
CONCLUSION: The study identifies MBO, gastric cancer, COVID-19, PPC, and VTE as potential risk factors for mortality in cases of intestinal obstruction. These findings highlight the necessity for continuous monitoring of indicators related to these mortality risk factors and their associated complications, thereby offering valuable insights for the management and treatment of intestinal obstruction.
FIELD: medicine. SUBSTANCE: proposed preparation is used in adults and children as a component of infusion therapy by intravenous route. Daily dose for adults and children is 5-20 and 5-10 mg/kg, respectively, for 3-5 days. Preparation is an aqueous solution of salts: sodium chloride, potassium chloride, calcium chloride, magnesium chloride and sodium acetate. Preparation is used for correction of an aqueous-electrolyte balance and metabolic acidosis. EFFECT: enhanced effectiveness of agent proposed.
Participants will be provided with the take-home MyoTrain system, which includes the MyoTrain armband, iPad, and MyoTrain software. Participants will progress through the training modules of the MyoTrain software, starting with eliciting paired single DoF antagonistic movements and ending with the proportional control of complex, 2-DoF hand and wrist movements.
FIELD: medicinal industry, pharmaceutical technology. SUBSTANCE: invention relates to production of preparations used as medicinal agents in dysbacteriosis, chemotherapy and digestive tract diseases. Method involves culturing industrial strains of corresponding microorganisms in stainless reactors at temperature 37 ± 1 C at stirring and under aeration in nutrient medium containing hydrolyzates of protein substrates with addition of ammonia, glucose for 6-7 h, pH value is 5.5-8.0 followed by pouring the prepared bacterial mass in ampoules or flasks, its freezing and the following liophilic drying. Before pouring method involves concentration of bacterial mass on ceramic filters with cutting off the fraction of size 0.2-0.4 mcm in feeding bacterial mass by tangentially to filtration surface. EFFECT: reduced time of liophilic drying and energy consumption, elevated storage time. 4 ex
This study aimed to develop a screening test for children suspected of developmental language disorders (DLD). The study was conducted in six steps. In the first two steps, we collected 34 sentences for the sentence repetition (SR) subtest, and 40 non-words for the non-word repetition (NWR) subtest, respectively. Experts determined the content validity in the third step and 19 sentences and 19 non-words were selected. In the fourth step, we draw simple pictures for the SR subtest. In the fifth step, two pilot studies were conducted on 30 and 35 Persian-speaking children aged 4.5-5.5 years, respectively. After calculating the discrimination index of the items, we removed items with the discrimination index less than 0.3. Nineteen sentences and 14 non-words remained in this step. In the sixth step, 92 typically developing (TD) children aged 4.5-5.5 and 10 children suspected of DLD were recruited. Then, we removed some items and evaluated the construct validity and reliability of the final form of the Persian Grammar-Phonology Screening Test (PGPST).The final form of the PGPST consisted of 16 sentences, and 11 non-words were developed. The correlation between the two subtests was 0.29. Children suspected of DLD in SR (p = .001) and NWR (p = .007) performed significantly worse than the TD children. The correlation between the two administrations of the test was 0.74 and 0.71, respectively, for SR and NWR. Cronbach's alpha was also 0.84 and 0.86 for the SR and NWR subtests, respectively. The PGPST is a quick and brief screening test with acceptable validity and reliability.
OBJECTIVE: To assess the Clinical Characteristics and Outcomes of Traumatic Brain Injury in Patients Admitted to the Surgical Ward of Jimma Medical Center, Southwest Ethiopia from January to July 2022.
DESIGN AND SETTING: A hospital-based prospective observational study was conducted among 175 patients admitted with Traumatic Brain Injury at Jimma Medical Center from January to July 2022. Data were collected by structured questionnaires and a convenient sampling technique was used. For data entry, Epidata V.4.6.0.5 software was used and exported to Stata V.14.0.2 for analysis. The Cox regression model was fitted to evaluate the predictors of mortality and variables with a p value <0.05 at 95% CI were taken as statistically significant predictors.
RESULTS: The incidence of in-hospital mortality was 22 (12.6%). The mean length of hospital stay was 6 days. In-hospital complications were recorded in 32.0% of patients. A Glasgow Coma Scale (GCS) score of <8 on admission (adjusted HR (AHR)=6.2, 95% CI 0.75 to 51), hyperthermia (AHR: 1.7, 95% CI 1.02 to 3.05) and lack of prehospital care (AHR: 3.2, 95% CI 2.2 to 8.07) were predictors of mortality in patients with traumatic brain injury.
CONCLUSION: In-hospital mortality was recorded in over one-tenth of patients with traumatic brain injury. The GCS score of <8 on admission, hyperthermia and lack of prehospital care positively affected the outcome of patients with traumatic brain injury. Screening of patients for hyperthermia and antipsychotics should be strengthened to reduce death. However, a multicentred study is needed for further evidence. Giving priority to the patients with those predictors will decrease the number of deaths.
A composition for dental use for the protection of dentine fabric during filling or the application of prosthetic members. In a first use as a protective film for the dentine tissue it comprises gum benzoin, a volatine organic solvent and a sealing and/or calcifying substance. More specifically the composition used as a protective film comprises gum benzoin 0.5 - 20%, volatile organic solvent 60 - 99% and sealant and/or calcifying substance 0.5 - 20%. In the case of medication cement for temporary fillings the composition of the powder part comprises, in addition to gum benzoin, zinc oxide, zinc acetate, zinc stearate, while the liquid part comprises eugenol and silicone oil. The general proportion by weight with which the gum benzoin is combined with the other powder components is zinc oxide 60 - 80%, zinc acetate 0 - 1%, zinc stearate 0 - 2%, gum benzoin 20 - 40%, while for 100 ml of the liquid part there are present 30 - 85 ml of eugenol, 0 - 30 ml of silicone oil, and sufficient alcohol for 100 ml. The antibacterial properties of the gum benzoin, hitherto only known for treatment of the respiratory tract, makes it possible to obtain an ideal coating composition for the dental field.
A method of computer aided treatment planning is performed by generating and manipulating a three dimensional (3D) image of a region which includes at least one anatomical structure for which treatment, such as surgery, biopsy, tissue component analysis, prothesis implantation, radiation, chemotherapy and the like, is contemplated. A virtual intervention, which simulates at least a portion of the contemplated treatment, is performed in the 3D image. The user can then determine the effect of the intervention and interactively modify the intervention for improved treatment results. Preferably, a warning is automatically provided if the intervention posses a risk of detrimental effect. The user can navigate through the contemplated region in the 3D image and asses the results. The treatment plans can be saved for comparison and post treatment evaluation.
The invention relates to a preparation method for Fusarium sp. pigment. According to the invention, a semi-preparative high performance liquid chromatography separation and purification system and an anti-phase C18 filling material are used, and water (containing trifluoroacetic acid) and methanol are used as mobile phases. The preparation method for the Fusarium sp. pigment has the advantages of simple operation, high efficiency, low cost and capacity of preparing the Fusarium sp. pigment with purity of more than 99.0%.
Methods, apparatuses, and systems for edge computing in surgical robotics is provided. The system comprises a surgical robot communicatively coupled to a 3rd party operating room equipment system over a cloud network. The surgical robot includes an operating room hardware configured to perform a surgical procedure on a patient. A memory is communicatively coupled to operating room hardware and user interface, and the memory comprises an equipment database and a threshold database to store parameters related to the operating room hardware. A processor, coupled to the operating room hardware via the network interface, is configured to establish a connection between the surgical robot and the 3rd party operating room equipment system, and monitor events being performed by the operating room and then store the monitored data within the threshold database. The threshold database stores trigger values for each piece of equipment for taking actions, based on data collected by sensors.
FIELD: cosmetic industry. SUBSTANCE: agent has gel, enzyme preparation and bioactive additions. Polyethylene oxide is used as gel and collase - as enzyme preparation. Bioactive additions - sea buckthorn or fir oil and propolis extract were taken at the following ratio of components, wt.-%: enzyme preparation collase 0.001-0.05; sea buckthorn or fir oil 0.2-5.0; propolis extract 0.1-10.0, and polyethylene oxide gel - the rest. Proposed agent does not contain elastase that can exhibit toxic and allergic action on the human organism. EFFECT: enhanced quality of agent proposed.
The invention discloses an externally-applied liniment for treating purulent otitis media. The liniment comprises active ingredient and carrier material. The active ingredient comprises compound Sulfamethoxazole 66.6--76.6%, and alumen exsiccatum 33.3-43.3%. The carrier material is 1% erythromycin ointment. The preparation method comprises grinding compound Sulfamethoxazole and alumen exsiccatum together, adding erythromycin ointment, and stirring. the liniment can effectively soften and eliminate ear infection diseases, relieve pain; and can be used for treating purulent otitis media, purulent otitis externa, and auricle impetigo. The invention also discloses the application of the liniment in pharmacy.
Patients with non-Hodgkin's lymphoma who previously responded with a duration of response of at least 3 months to Iodine-131 Anti-B1 Antibody therapy will undergo two phases of study. In the first phase, patients will receive a dosimetric dose of unlabeled Anti-B1 Antibody (450 mg) followed by Anti-B1 Antibody (35 mg) which has been radiolabeled with 5 mCi of Iodine-131. Whole body gamma camera scans will be obtained after the dosimetric dose and data from three imaging time points will be used to calculate a patient-specific dose to deliver the desired total body dose of radiotherapy. In the second phase, patients will receive the therapeutic dose of unlabeled Anti-B1 Antibody (450 mg) followed by 35 mg of Anti-B1 Antibody labeled with the patient-specific dose to deliver the desired whole body dose of radiation. Patients will be treated with thyroid blocking medication at least 24 hours prior to the first infusion and continuing for 14 days following the last infusion.
The invention provides a biocompatible antibacterial peptide with self-assembly potential, a preparation method and application thereof, and solves the problem of poor selectivity of strong-toxicity cells of natural antibacterial peptide. The antibacterial peptide contains hairpin structure D PG corner unit, its sequence is shown in SEQ ID No. 1. The preparation method comprises the following steps: by combining FF with Ile and introducing hairpin structure D PG corner unit, choose positive charge amino acid arginine, hydrophobic amino acid leucine as the repeated binary sequence unit to distribute over both sides, guarantee its hydrophobic nature and number of positive charges that exert the antibacterial function and need, the antibiotic peptide F2I-LL with low toxicity and high selectivity of assembling ability is obtained in the brand-new design. The antibacterial peptide is applied to the preparation of medicaments for treating infectious diseases of gram-positive bacteria or/and gram-negative bacteria. The antibacterial peptide has certain assembly capacity, strong antibacterial activity and very low hemolytic effect on blood cells.
Transoral robotic excision will be carried out using the da Vinci surgical robot. The spatula cautery will be used to remove the tumours with 1 cm margins. At the time of surgery circumferential margins will be taken and sent for frozen section analysis. The resection will proceed until negative margins are obtained if feasible.
Estrogenic extracts of Asparagus conchinchinensis (Lour.) Merr of the Liliaceae Family are provided. Also provided are methods of using said extracts to achieve an estrogenic effect, especially in a human, e.g. a female human. In some embodiments, the methods include treatment of climacteric symptoms. In some embodiments, the methods include treatment of estrogen receptor positive cancer, such as estrogen responsive breast cancer.  In some embodiments, the methods include treatment or prevention of osteoporosis.
PURPOSE:To provide the titled activating agent which attacks the tumor cells and contributes to elongate the life of the host, by using an antibiotic substance found in the product of Nocardia sp. No.2-200 strain, as an active component. CONSTITUTION:The agent contains the compound of formula as an active component. The compound of formula is an antibiotic substance found in the product of Nocardia sp. No.2-200 strain (FERM-P No.4171), and exhibits biophylaxis- activating activity as well as antibacterial activity, i.e. improving the phagocytic activity of macrophage, preventing the infection of mouse with Candida albicans having no antibacterial activity, attacking the tumor cells, and elongating the life of the host. The compound is extremely low toxic, and its LD50 to mouse is 705mg/kg by intravenous injection and 810mg/kg by peritoneal infusion. There is absolutely no delayed toxicity. It can be absorbed by oral administration, exhibits high concentration in blood and organs, and can be discharged rapidly.
There is some evidence in the literature suggesting better effects of pain neuroscience than "traditional pain education" based on pain self-management ("living despite the pain") and biomedical models. As the focus is based on cognitive change, pain neuroscience programs could be more effective than pain self-management programs, contributing to reconceptualize beliefs and minimize the level of threatening perceived by the brain. Gallagher et al (2013) reported effects of a pain neuroscience education program based on a book of metaphors compared to a pain self-management program (Back book) and reported greater immediate from pain neuroscience education on pain catastrophizing and pain knowledge. The hypothesis of this study is that a pain neuroscience education will show more effective results for pain intensity, catastrophizing and pain self-efficacy when compared to the pain self-management program in patients with CLBP. The purpose of this study will be to compare the immediate effects of an educational program focused on Pain Neuroscience Education vs. Pain self-management program for patients with chronic low back pain (CLBP) considering the outcomes of pain intensity, catastrophizing and pain self-efficacy. The investigators will recruit 108 with CLBP between 18 and 60 years and both genders. The sample size will be randomized into two arms: fifty participants will be submitted to Pain Neuroscience Education and the remaining fifty to Pain Self-Management education. Both interventions will be administered in one session (50 minutes). The programs will be showed as interactive workshops. Participants will be submitted to a brief initial assessment considering: pain intensity, fear of movement, anxiety and depression, catastrophizing, pain self-efficacy and global perceived effect.
The invention discloses a breast cancer stem cell specific binding polypeptide and application thereof in preparing a medicament for treating breast cancer. The amino acid sequence of the breast cancer stem cell specific binding polypeptide is SEQ ID NO. 1. The breast cancer stem cell specific binding polypeptide can be used for preparing a medicament for treating breast cancer. The drug or the nano material coupled or combined with the breast cancer stem cell specific binding polypeptide can specifically identify, diagnose and treat breast cancer. The invention provides theoretical basis and technical support for applying the breast cancer stem cell specific binding polypeptide to diagnosis and treatment of breast cancer, and has wide application prospect.
The target intensity for the INT group is 2 min at about 95% of baseline VO2max followed by 2 min of recovery at 40-50% of VO2max. Regardless of the training method each participant will be "locked" into a weekly energy expenditure of 12 kilocalories per kilogram of body weight per week (KKW).
Clinical trials in patients with polyarticular juvenile idiopathic arthritis were performed using other formulations of methotrexate.

In a 6-month double-blind, placebo-controlled trial of 127 pediatric patients with pJIA (mean age, 10.1 years; age range, 2.5 to 18 years; mean duration of disease, 5.1 years) on background nonsteroidal anti-inflammatory drugs and/or prednisone, methotrexate given weekly at an oral dose of 10 mg/m2 provided significant clinical improvement compared to placebo as measured by either the physician’s global assessment, or by a patient composite (25% reduction in the articular-severity score plus improvement in parent and physician global assessments of disease activity). Over two-thirds of the patients in this trial had polyarticular-course JIA, and the numerically greatest response was seen in this subgroup treated with 10 mg/m2/wk methotrexate.

The overwhelming majority of the remaining patients had systemic-course JIA. All patients were unresponsive to NSAIDs; approximately one-third were using low dose corticosteroids.

Weekly methotrexate at a dose of 5 mg/m2 was not significantly more effective than placebo in this trial.