anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
Abstract Method and Product for Promoting Improved Meat Quality in Meat Producing Animals The growth rate of meat-producing animals as well as the yield and quality of the meat obtained therefrom is improved by administering to the animal prior to its sexual maturation an effective amount of a female gonadal steroidal compound; namely, an estrogen or progestagen compound and preferably a mixture thereof, sufficient to delay development of the gonadal function of the animal, e.g. spermatogenesis. Such administration is terminated sufficiently prior to slaughter of the animal that the administered steroidal compound has been substantially completely removed from the animal's system which before slaughter exhibits levels of the corresponding natural hormones therein substantially within normal limits.  In mammals, administration is preferably by injection, but in fish, shellfish and poultry, the active steroidal compound is incorporated at low levels in the usual feed therefor.  In mammals, the treatment is preferably applied to uncastrated males but can be extended to females and castrated males if desired; while in fish, shellfish and poultry administration is without regard to sex.  The ratio of lean meat to fat is increased significantly by the treatment and in male mammals aggressiveness and odor development with consequential tainting of the meat is suppressed until slaughter.          (Fig. 1)
PURPOSE: This study seeks to investigate demographics of patients with Madelung deformity in a large, geographically diverse sample and understand patient and caregiver perceptions of the impact of this condition. We hypothesized that patients with untreated Madelung deformity have greater pain and lower function compared to the normal population but are less affected than the chosen control group, namely, patients with proximal radioulnar synostosis (PRUS).
METHODS: This retrospective study queried the Congenital Upper Limb Differences (CoULD) Registry, a multicenter registry of patients treated in tertiary care pediatric hospitals. We searched patients enrolled as of July 2022 and identified 3,980 total patients and 66 (1.7%) with a diagnosis of Madelung deformity. We reviewed demographics and Patient-Reported Outcomes Measurement Information System (PROMIS; peer relations, depressive symptoms, pain interference, and upper extremity function domains) scores at time of enrollment. We used a matched cohort comparison with propensity scoring for 50 patients with Madelung deformity and 50 patients with PRUS (control cohort).
RESULTS: Patients with Madelung deformity presented at an average age of 13.1 years (± 2.1 years). Ninety-eight percent were female, and 82% were White. Seventy-four percent had distal radius-only deformity. Upper extremity PROMIS scores in both the Madelung deformity and the PRUS groups were significantly "worse" than normal, confirming our hypothesis. The Madelung deformity and PRUS cohort scores were not consistently different from one another. PROMIS scores from all other domains, including pain interference, were similar to, or better than normal for both groups, disproving the second part of our hypothesis.
CONCLUSIONS: Patients with Madelung deformity averaged 13 years of age and were nearly all female, and the majority had only distal involvement of the radius. Patients with Madelung deformity had lower function based on PROMIS scores, similar to the control cohort, whereas all other PROMIS measures were similar to or better when compared to normal values. Pain interference scores in both cohorts were lower than normal values. Patients with Madelung deformity have decreased function, similar to the comparative cohort of patients with PRUS, but do not present with increased pain.
TYPE OF STUDY/LEVEL OF EVIDENCE: Symptom Prevalence III.
PROBLEM TO BE SOLVED: To monitor biological information in real-time even when a patient, etc. is staying away from a monitoring device.SOLUTION: A first monitoring device 10 includes a first display unit 11 and a first connector 12. A portable second monitoring device 20 includes a second display unit 21, a second connector 22, and a signal input unit 25. The signal input unit 25 receives an input of a measurement signal related to biological information. The second display unit 21 displays information corresponding to the measurement signal. When the first connector 12 is connected to the second connector 22, the second display unit 21 becomes a non-display state and also the information corresponding to the measurement signal is displayed in the first display unit 11.
Forty obese men (BMI 35-40 kg/m2,18-40 years of age) will be randomly assigned to one of four treatment interventions: 1) Calorie restricted; 2) Calorie restricted and HMB supplemented; 3) No calorie restriction; and 4) No calorie restriction and HMB-supplemented. Over the 8 week interventional period the calorie restricted group is expected to lose 3-5% of initial body weight. Anthropometric measures will be taken weekly, and dual energy x-ray absorptiometry (DXA) body composition and strength will be measured before and after 8-weeks of intervention. Blood and urine will be collected and analyzed at 0, 4, and 8 weeks. Additionally Dietary records and questionnaires concerning quality of life will be administered, and activity will be assessed using questionnaires and pedometers. Muscle biopsies will be taken before and after the 8-week study.
PURPOSE: A cosmetic composition containing natural plant extract is provided to suppress moisture evaporation and to soften the hair. CONSTITUTION: A cosmetic composition for improving hair condition contains natural plant complex ingredients including Nymphaea tetragona var. extract, ginger extract, and bamboo extract as an active ingredient. The composition further contains 50.0-80.0 wt% of camellia oil, green tea seed oil, and avocado extract in a ratio of 1-10:1-10:1-10. The complex ingredients contain butylene glycol or phenoxy ethanol as an antiseptic. The composition further contains polarity silicon, polymer silicon, or silicon resin.
A method for searching and presenting data is provided. The method comprises receiving a search query at a computer having a 64 bit processor, the computer having one or more data repositories comprising data related to the query and a set of code set mappings mapping the data to a code set stored in a database. The code set includes at least one domain, a plurality of concepts within the at least one domain, and a plurality of lexicals also within the at least one domain. A lexical is an alternative way to express a concept. Each concept is arranged in a one-to-many relationship with one or more lexicals. The method further comprises executing, by the processor, a lexical-based search function to determine an exact or approximate match between the search query and one or more lexicals in the one more code sets. The method also comprises serving one or more exact or approximate matches to a user.
Ultrasound (US) guided dorsal penile nerve block with in plane technique was done. Half of the total 0.2 ml/kg dose of 0.25% bupivacaine was administered while observing its distribution with US. The same procedure was then repeated on the other side of the penis.
An aqueous suspension of procaine pencillin contains 0.05 to 3, and preferably 0.5 to 2 per cent of lecithin and 0.05 to 2, and preferably 0.05 to 0.67 per cent polyvinylpyrrolidone, based on the final aqueous suspension.  For suspensions containing 300,000 units procaine penicillin per ml, it is preferred to use 1 per cent lecithin and 0.1 per cent polyvinylpyrrolidone.  The lecithin is preferably in excess of the polyvinylpyrrolidone, especially 3:1 to 10:1.  A dry preparation to which sterile water is added when required for use, contains in addition to the above a water-soluble penicillin salt e.g. the sodium, potassium, calcium, ammonium and thiethylamine salts.  Sodium citrate and the preservative butyl-p-hydroxybenzoate may also be present.  Other additions are preservatives such as alkyl p-hydroxybenzoates other than butyl, phenol and cresol; antibiotics such as streptomycin and dihydrostreptomycin; and suspending agents such as carboxymethyl cellulose.
This invention relates to herbal formula extracted from different seven plants for the treatment of chronic bronchial asthma. These plants are available in Egypt; chamomile flowers, anise, fennel and caraway fruits, licorice roots, cardamom and black seeds. These herbs are boiled in water (as will be mentioned in details) and can be drunk hot, warm or cold as favored by patient once in the morning and once in the evening. This herbal tea helps in the treatment of the symptoms of bronchial asthma in respect to cough frequency and intensity as well as sleep discomfort. This was evident in vivo study clinically on volunteer patients and in vitro study on rat mast cells; as it inhibits the release of Histamine, which causes allergy. It was proven that this novel herbal tea enhances the respiration by measuring FEVI/FVC for patients who used the tea in addition to a lower dose of their medicines under a physician's supervision.
Blood samples are taken on day 0 and day 1 and stored for later analysis. The investigator treats the patients according to standard of care.
Placement of penile prosthesis had been well described in the outpatient setting, however, one barrier to same-day discharge is postoperative urinary retention (POUR). POUR remains a condition encountered during ambulatory surgical procedures and has yet to be characterized in patients undergoing penile prosthesis. We characterized POUR in a cohort of penile prosthesis recipients along with risk factors and management. Patients undergoing penile prosthesis implantation from 2014 through 2020 without pre-existing retention were included. All patients underwent a void trial immediately following penile prosthesis in the post-anesthesia care unit. POUR was strictly defined as (1) any patient requiring catheter replacement after prosthesis, (2) a rising post-void residual, or (3) inability to void after 6 h regardless of whether a catheter was placed. Independent procedures, demographic, intraoperative, and postoperative risk factors for POUR were assessed. 317 men were included of whom 27.1% experienced POUR. Men experiencing POUR and those not in retention were essentially indistinguishable with respect to previously described risk factors for POUR. Only use of both α-blockers and 5-α-reductase inhibitors was significantly associated with a greater risk of POUR, a finding maintained on adjusted analysis (adjusted odds ratio 10.1, 95% confidence interval 2.1 to 49.8). POUR resolved without intervention in 3.5%, a single episode of clean intermittent catheterization (CIC) in 7.0% of patients, and repeated CIC or indwelling catheter placement with a successful delayed void trial in 88.4% of patients. Rate of prosthesis infection in patients who experienced POUR did not significantly differ from those who did not experience POUR (4.7% vs. 2.2% p = 0.26). Our findings suggest that POUR is experienced in as many as 1 in 4 men undergoing penile prosthesis placement, most of whom must be managed with indwelling catheterization or repeated CIC. Those with indicators of symptomatic prostate enlargement are at significantly greater risk of urinary retention.
This disclosure is directed to the preparation of oily microcapsules which can be easily tray dried to a free flowing product without requiring special drying equipment. These microcapsules have a cell wall material having a first cell wall of gelatin/carboxymethylcellulose (CMC) which is prehardened (cross-linked) with a material selected from the group consisting of formaldehyde, glyoxal and glutaraldehyde to which there is grafted formaldehyde and urea. The predominant portion, viz., approximately 95% by wt. of these microcapsules have a particle size less than 1500 microns and more characteristically have a particle size ranging from about 100 to about 400 microns (microcapsular diameter). These microcapsules contain less than approximately 3 wt. % free oil and more characteristically less than about 1 wt. % free oil (non-microencapsulated oil) and have less free (unreacted) formaldehyde, which can be extracted with water, than do prior art microencapsulated oily materials. The microcapsules of this invention are granular and free-flowing when dried.
(A) in the mfr. of a high strength, bioactive, composite ceramic material, used for dental or orthopedic implants, involving prepn. of a powder mixt. of a first bioinert matrix-forming powder and a second calcium phosphate-based powder, (a) the first powder comprises one or more of TiO2, ZrO2 and Al2O3; (b) the second powder mainly comprises hydroxyapatite and/or tricalcium phosphate; and (c) the powder mixt. is compacted and then hot isostatically pressed at above 50 MPa to obtain a composite material in which hydroxyapatite and/or tricalcium phospahte are evenly dispersed in a metal oxide matrix. (B) In a modification, the first powder mainly comprises silicon and the compacted green body is nitrided to cause silicon nitride formation and densification. (C) A novel composite ceramic material comprises a high strength inert matrix contg. 5-35 (pref. 10-25) vol.% of an even dispersion of calcium phosphate based particles of 30 microns max. size and max 5 (pref. max. 2) microns mean particle spacing. (D) Also claimed is a body comprising one or more portions of the body mainly comprising one or more of TiO2, ZrO2 and Al2O3.
The SMS based intervention will be developed through formative research including focus groups, cognitive interviews, and a pilot test of a Spanish version of mDIET. The focus groups will be conducted with both English and Spanish speaking men and women to 1) learn more about the content areas to be addressed in the intervention including physical activity and sedentary behaviors to expand on previous research; 2) learn more about assessing equivalence and compatibility in intervention messages in English and Spanish; 3) identify the most culturally and linguistically appropriate messages; 4) assess text message use; 5) identify factors that influence food and physical activity decisions; and 6) identify health messages that Latinos see as most understandable, credible, and persuasive, cognitive interviews, and a pilot test of a Spanish version of mDIET. The cognitive interviews will be conducted in Spanish and will help inform translation of study materials (text messages and measures) from English to Spanish. An 8-week pilot test of the Latino (Spanish language) mDIET will be conducted to ensure that the text messages and SMS system works as expected in terms of usability and acceptability.

The randomized controlled trial will be a 12-month intervention with 309 study participants. Participants will be randomized to one of three groups: SMS-only, SMS plus phone counseling, and a control group (Details of the study arms are discussed in another section). The goals of the intervention groups (SMS-only and SMS plus phone counseling) include: 5% weight loss, 500 k/cal per day deficit through reduced caloric intake and increased energy expenditure, 12,00 steps through the use of a pedometer, and a reduction in sedentary behaviors. Participants will receive daily text messages, self-monitoring tools, and brief health promotion printed or wed materials on physical activity, nutrition, or other weight loss related topics. Participants will complete physiological and survey measures at baseline, 6 months, and 12 months to assess weight (BMI), physical activity and diet behaviors, psychosocial behaviors, environmental factors, and exposure and satisfaction with the program.
Pescadillo ribosomal biogenesis factor 1 (PES1), a nucleolar protein initially identified in zebrafish, plays an important role in embryonic development and ribosomal biogenesis. Notably, PES1 has been found to be overexpressed in a number of cancer types, where it contributes to tumorigenesis and cancer progression by promoting cell proliferation, suppressing cellular senescence, modulating the tumor microenvironment (TME) and promoting drug resistance in cancer cells. Moreover, recent emerging evidence suggests that PES1 expression is significantly elevated in the livers of Type 2 diabetes mellitus (T2DM) and obese patients, indicating its involvement in the pathogenesis of metabolic diseases through lipid metabolism regulation. In this review, we present the structural characteristics and biological functions of PES1, as well as complexes in which PES1 participates. Furthermore, we comprehensively summarize the multifaceted role of PES1 in various diseases and the latest insights into its underlying molecular mechanisms. Finally, we discuss the potential clinical translational perspectives of targeting PES1, highlighting its promising as a therapeutic intervention and treatment target.
Pancreatic cysts were rarely reported previously, however, the increased use of advanced imaging techniques (mainly computerized topography and magnetic resonance imaging), for evaluating suspected pancreatic pathology or for other medical reasons has increased the detection of pancreatic cysts. Prevalence can range from 2.5-38% (1,3). These rates vary by patient's age and modality of imaging used (i.e: CT vs MRI). The rate of a malignant transformation in pancreatic cysts is not well known, however, very low. A study using the SEER data reported this rate to be 10.8 for every 100,000 women, or 13.8 for every 100,000 men with more than 85% of malignancies being detected in patient's age 40-84 years of age. (4) The most common histological type was adenocarcinoma, with mucinous producing tumors making about 4% of all adenocarcinomas detected. Pancreatic cysts are categorized under two major groups; serous and mucinous. Serous cystadenomas are thin walled cysts and are not associated with precancer. Mucinous cysts on the other hand have various diameters and contain viscous fluids which have the tendency to progress to pancreatic cancer. Radiofrequency ablation was recently proposed as an alternative for patients who could not or would not undergo surgical resection. In a recent study under the title "Endoscopic ultrasound guided radiofrequency ablation, for pancreatic cystic neoplasms and neuroendocrine tumors", eight patients with pancreatic cystic lesions were recruited for the study. Six patients had pancreatic cystic neoplasm. Post procedure imaging in 3-6 months showed complete resolutions of the cysts in 2 cases after using EUS RFA. No major complications were observed within 48 hours after the procedure, and two patients had mild abdominal pain which was resolved within 3 days after the surgery. (1) Management of pancreatic cysts includes surgical or non-surgical, or can be observational with repeat imaging. Management type depends on factors including pathologic features of the cyst on imaging (cyst size, enhancing cyst walls, duct size...etc), and the patient's ability to undergo surgery. Older patients with preexisting morbidities may not be eligible for a surgical resection, thus the use of endoscopic ultrasound interventions maybe appropriate. Endoscopic ultrasound guided radio frequency ablation has been used in treating certain pancreatic lesions, with a favorable pancreatic outcome (5)
Depression is a common but serious mental disorder that affects millions of people each year. Depression can severely impact people's lives, causing them to often feel sad and hopeless, as well as affecting people's sleep patterns, concentration, and energy levels. Women with a history of abuse are at an increased risk for developing symptoms of depression. However, treatments such as interpersonal psychotherapy and individual psychotherapy have been known to reduce symptoms of depression. This study will compare the effectiveness of individual and interpersonal psychotherapy in improving depressive symptoms and daily functioning in depressed women with a history of sexual abuse.

Participants in this study will undergo a two-part screening interview at the Strong Adult Ambulatory Clinic. This screening will include both written questionnaires and face-to-face interviews regarding any experiences of sexual or physical abuse; suicidal thoughts; family relationships; and current attitudes, thoughts, or feelings. Participants who meet all criteria will then be randomly assigned to receive one of two treatments: interpersonal psychotherapy or individual psychotherapy, which is considered usual care. All treatment sessions will be held at the Strong Adult Ambulatory Clinic. Participants assigned to receive interpersonal psychotherapy will attend weekly 50-minute sessions with a therapist. Interpersonal psychotherapy will focus on current interpersonal stressors in daily life, such as difficulties in close relationships or at work. Treatment will also help participants examine the relationship between their mood changes and interpersonal problems. Participants assigned to receive individual psychotherapy will undergo cognitive-behavioral therapy, supportive counseling, or a combination of the two. Participants will work with their therapists to decide upon a treatment plan designed to help changes in mood and other difficulties in daily life. The number and length of treatment sessions for this group will be determined on an individual basis. For all participants, evaluations consisting of questionnaires similar to those from the initial screening will be completed at mid-treatment, post-treatment, and 3 months after treatment.
Disclosed are a whitening and anti-inflammatory composition containing plant extracts of Distylium racemosum Siebold & Zucc., Chinese mulberry, and Eupatorium makinoi var. oppisitifolium (Koidz.) Kawahara & Yahara as active ingredients; and to a production method thereof. According to the whitening or anti-inflammatory composition containing the plant extracts, it is possible to obtain skin-whitening, antioxidant, and anti-inflammatory effects by mixing the plant extracts obtained from Distylium racemosum Siebold & Zucc., Chinese mulberry, and Eupatorium makinoi var. oppisitifolium (Koidz.) Kawahara & Yahara, thereby inhibiting activity of tyrosinase.
Participants in the intervention group visit their general practitioner at baseline and 4, 8, and 12 weeks. At each visit, participants complete MADRS-s for the assessment of depression severity and discuss the results with their GP in a patient-centered consultation.
The invention provides a brand-new gated memory neural network model based on information similarity. The model designs a new gate control memory unit based on information similarity, makes full use of image characteristic vectors extracted by the underlying network model, and can perform classification and memorability storage and update on image characteristic information. The information memorized by the gate control unit is different from the implicit memory of the traditional RNN network, has higher expressiveness and can be stored. The defect that the features extracted by the traditional convolutional neural network are individualized due to the dependence on corresponding images is overcome, and the defect that the recurrent neural network can only form a training mechanism similar to memory and cannot store and update class feature memory per se is overcome. The loss function is designed by using an IBS distance measurement method to endow the memory unit with the type attribute, the iterative memory storage function of the gate control memory unit is designed by using an IBS algorithm, and the memory library of the image type characteristics can be stored and updated for a long time. In addition, the network combines category memory and individual characteristics of the images to participate in network classification training, and the accuracy of network classification is improved by the aid of memory participation. Through testing, the network has very strong accuracy and applicability in the aspect of image classification.