anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
The participants in the action observation group were given instructions to perform a daily training comprised of two sets of activities. The main set consisted of 10 isometric hand grip contractions for 3 seconds each with a tennis ball, leaving a 20-second break between contractions. In the first set, the participant simply watched a video that showed a forearm performing the task, placed in the standard position and with the tennis ball in the hand. Once that first set was completed, the participant took a 2-minute break before starting the second set, in which they performed the 10 isometric contractions with the tennis ball while they watched the video.
This protocol includes 5 to 10 min of warm-up, 1 hr of RR, and 15 to 20 min of functional activities training. The treatment intensity is 1.5 hours/day, 5days/week for 4 consecutive weeks. The RR session uses the robot-assisted arm trainer, Bi-Manu-Track (Reha-Stim Co., Berlin, Germany).
Between 4 and 72 hours prior to start of HCT conditioning therapy, patients receive a placebo IV. Beginning 8 weeks after IV placebo, patients receive a placebo SC on days 50 (+/- 5 days), 100 (+/- 7 days), and 160 (+/- 7 days) post-HCT in the absence of grade III-IV acute GVHD, disease relapse, or unacceptable toxicity. NOTE: HCT infusion takes place on day 0.
PURPOSE:To prepare the titled health tea agreeable to take, by mixing finely cut and shade-dried leaves of EZOUKOGI (Acanthopanax senticosus), chopped and shade-dried shoot of KUMAZASA (Sasa albo-marginata), dried peppermint leaves, and finely ground corn at proper ratios. CONSTITUTION:The leaves of EZOUKOGI collected in the latter part of May- the latter part of June, are washed with water, cut into small pieces, and dried in the shade. The round sprout of KUMAZASA is pulled out from the shoot in the middle of June-July, washed with water, cut to 2-3mm. long, and dried in the shade. Leaves of peppermint are collected in July-August, washed with water, cut to 2-3mm., and dried in the shade. Corn is harvested in the middle of September-at the beginning of October, dried completely and finely ground. The ground corn is parched over a strong fire, and the other components are mixed together and parched over a slow fire preventing the scorch. The four kinds of the components are mixed together to obtain the objective EZOUKOGI tea. EFFECT:The active component of EZOUKOGI can be extracted together with other ingredients in a short time.
The invention relates to the technical field of insole structures, in particular to a therapeutic massage insole. The therapeutic massage insole comprises a body, and the body is provided with at least three small through holes. Large through holes are formed in the heel of the body. Small button cushion bodies are embedded in the small through holes, and large button cushion bodies are embedded in the large through holes. Each small button cushion body is composed of a medicine block and a cotton cloth wrapping the medicine block, and the shape of the medicine blocks is identical with that of the button cushion bodies. Compared with the prior art, the therapeutic massage insole has the advantages that through combination of the energy medicine and the traditional Chinese medicine, anions, far infrared rays and other components facilitating human health can be continuously released to a human body through the sole; the therapeutic massage insole has the effects of dispelling wind and eliminating dampness, clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, strengthening the spleen and stomach, tonifying Qi, improving the body blood circulation system and the like, and has the dual effect of the medicine health care and traditional Chinese medicine massage; the therapeutic massage insole is simple in structure, reasonable in arrangement, low in manufacturing cost and the like.
Perspectum's LiverMultiScan is a quantitative multiparametric MRI method, FDA-cleared and CE-marked, that is used to detect and stage early liver disease.It is already widely used internally in both research and within the clinical setting. LiverMultiScan has been adopted as the only liver scan in whole-population long term studies. The LiverMultiScan is more cost efficient, short in duration(\<15mins), non-invasive and safe(no IV or oral contrast required, no ionizing radiation and no venipuncture).

This is a registry where there will be no intervention to the standard of care. Registry volunteers will be required to attend a single visit that will involve having a multi-parametric MRI at no cost to them. In addition, the investigators will collect contact information of the volunteers including their email address, phone number and home address so that they can be contacted to discuss possible participation in future studies which may be sponsored by Perspectum or third parties, such as pharmaceutical companies.The volunteer's personal information shall never be shared with these third parties. Additionally, the contact information of the volunteers' medical providers shall also be collected so that the LiverMultiScan reports can be delivered to them.
PURPOSE:A carcinostatic agent having low side effects, comprising aloe as an active ingredient. CONSTITUTION:A carcinostatic agent for oral administration containing an extract of aloe (Aloe saponaria or Aloe arborescens) as a constituent components. An extract of a component from which a harmful factor is removed is administered by rectal, sublingual, inhalation and partial application besides injection preparation. This drug contains aloe which has high anti-cancer action and is effective against stomach cancer among plants which have been eaten and drunk. Stomach cancer and colon cancer mainly have glandular carcinoma and squamous cell carcinoma and this carcinostatic agent is effective against glandular carcinoma and squamous cell carcinoma of lung and has low side effects. Nowadays, a solid cancer mainly depends upon surgical ablation, but is is not said that its result is absolutely effective. Consequently, use of this drug with surgical therapy is much expected to improve treatment of patient.
BACKGROUND: Sarcopenia is typically assessed through hand grip strength, walking speed, and chair stand tests. However, it has been inadequately examined in terms of other physical fitness (PF) components in community-dwelling older adults. Thus, in this study, we explored factors influencing the risk of sarcopenia in community-dwelling older adults. In addition, we analyzed the clinicodemographic characteristics of older adults with or without sarcopenia and investigated the effect of sex on their PF.
METHODS: This cross-sectional study included 745 older adults from a community health promotion program in Taiwan. Their clinicodemographic characteristics were recorded. PF was assessed through various tests, such as hand grip strength evaluation, 8-foot up-and-go test (8-UGT), 2-min step test, and 6-m walk test. PF and factors influencing sarcopenia risk were compared between older adults with sarcopenia (sarcopenia group) and those without it (nonsarcopenia group). A logistic regression model was performed to identify key factors associated with sarcopenia. Its predictive performance was evaluated by calculating the area under the receiver operating characteristic curve (ROC) curve.
RESULTS: Regardless of sex, the sarcopenia group performed worse in almost all components of PF-for example, upper and lower limb muscular strength and endurance, cardiopulmonary fitness, and balance-than did the nonsarcopenia group. However, for men, no significant between-group difference was observed in flexibility. The logistic regression model indicated age (odds ratio [OR]: 1.107), sex (OR: 2.881), Mini Nutritional Assessment-Short Form scores (OR: 0.690), and performance in 8-UGT (OR: 1.346) as factors influencing the risk of sarcopenia. The model exhibited excellent discriminative ability in predicting sarcopenia, as indicated by an area under the curve value of 0.867 (95% confidence interval: 0.827-0.906; p < 0.05).
CONCLUSION: Older adults without sarcopenia tend to outperform those with sarcopenia in almost all PF measures, regardless of sex. Older age, male sex, low Mini Nutritional Assessment-Short Form scores, and poor performance in 8-UGT are associated with a high risk of sarcopenia.
The present invention provides an oral Chinese patent medicine for treating hyperostosis, which is composed of epimedium herb, prepared rhizome of rehmannia, desertliving cistanche, huaiguzi, medlar, suberect spatholobus, red sage root, sliced sornus cervi, cibot rhizome, eucommia bark and fleeceflower root. According to a traditional Chinese medicine recipe of the present invention, the Chinese patent medicine produced by a modern Chinese patent medicine extraction process is dark brown. The Chinese patent medicine of the present invention can be made into granules or tablets or medicinal powder or capsules according to requirements. The oral Chinese patent medicine for treating the hyperostosis of the present invention has the advantages of conspicuous curative effect, short course of treatment, low price, convenient oral administration and portability, and has the conspicuous curative effect on the hyperostosis. Practical application proves that the present invention effectives lightens and relieves the pain of patients. The oral Chinese patent medicine for treating the hyperostosis of the present invention makes a great contribution to relieving the pain of the hyperostosis patients.
Background and Objectives: Despite numerous described techniques, laparoscopy has yet to replace open surgery as the gold standard for inguinal hernia (IH) repair in children. This may be due to many variables, including the lack of long-term follow-up and concern for increased recurrence. In this study, we present our long-term follow-up data on children undergoing percutaneous internal ring suturing (PIRS) for IH repair. Materials and Methods: This retrospective cohort study included children who underwent PIRS for IH between May 2013 and May 2021 at three tertiary care institutions, with at least three years of follow-up. Age at surgery, side of IH, presence of contralateral patent processus vaginalis, surgical and anesthesia time, and complications were noted. Parents were contacted to enquire about long-term complications, such as recurrence. Results: Long-term follow-up (average 6.9 ± 2.3 years) was available for 714 patients. For unilateral and bilateral procedures, the average surgical time was 13.6 ± 5.4 and 19.9 ± 3.0, and the average anesthesia time was 27.7 ± 12.9 and 33.9 ± 14.1 min, respectively. Complications were seen in 0.84% of patients and 1.2% of procedures, and recurrence was observed in 0.98% of patients and 0.78% of procedures. Conclusions: Our study, with a nearly 7-year follow-up, provides substantial evidence that PIRS is a safe and effective technique for IH repair in children, with low recurrence and complication rates. Despite the study's retrospective nature and limited sample size, it contributes valuable data supporting the use of PIRS in pediatric IH repair.
Surgical site infection (SSI) continues to be a common complication of surgery. The real benefit of using topical antibiotics for the prevention of SSI in abdominal hernia repair surgery is still unknown. This study aimed to evaluate the usefulness of topical gentamicin in SSI prophylaxis in incisional hernia repair with mesh. A randomized controlled trial was conducted in patients undergoing open incisional hernia repair. Patients were randomly assigned to one of two groups: in the gentamicin group, each layer of the abdominal wall was irrigated with gentamicin solution before wound closure, and in the saline solution group (placebo), each layer of the abdominal wall was irrigated with normal saline solution. The incidence of SSI and other surgical site complications was compared between both groups, and the presence of adverse effects with the use of topical gentamicin. Data from 146 patients were included for analysis: 74 in the gentamicin group and 72 in the saline solution group. SSI was observed in six patients (8.1%) in the gentamicin group and eight patients (11.1%) in the saline solution group, with no significant differences (p = 0.538) between both groups. No statistically significant differences were observed in the presentation of seroma, hematoma, and surgical wound dehiscence between both groups. No adverse effects were reported from topical application of gentamicin. In this clinical trial, the use of topical gentamicin in incisional hernia repair with mesh did not significantly reduce the incidence of SSI. EU Clinical Trials Register: EudraCT 2018-001860-45 (04/07/2019).
Subjects will receive treatment sequence (DE) according to randomization which is a single 1500 mg (two tablets of 750 mg) dose of gepotidacin tablet (RC or HSWG) selected from Part 1a under fasted condition (Treatment D) in Period 1 followed by fed conditions (Treatment E) in period 2. There will be a washout period of at least 3 days between doses.
Five participants will be enrolled at the lower dose (0.33 ×10\^8 cells). Once safety and tolerability are adequately assessed, treatment will proceed to the higher dose level.
Disclosed herein are methods, systems, and apparatus, including computer programs encoded on computer storage media, for entity prediction. One of the methods includes performing word segmentation on text to be predicted to obtain a plurality of words. For each word of the plurality of words, a determination is made whether the word has a pre-trained word vector. In response to determining that the word has a pre-trained word vector, the pre-trained word vector for the word is obtained. In response to determining that the word does not have a pre-trained word vector, a word vector for the word is determined based on a pre-trained stroke vector. The word vector and the pre-trained stroke vector are trained based on a text sample and a word vector model. An entity associated with the text is predicted by inputting word vectors of the plurality of words into an entity prediction model.
Modified polypeptides capable of provoking the formation of antibodies in an animal may be produced by forming a linear polymer of polypeptide fragments, each having a molecular structure similar to a fragment of the protein to which antibodies are to be provoked. Such linear polymers can be made more immunogenic than the proteins to which they are related without introducing undesirable extraneous materials into the animal being treated, but have reproduc- able immunogenic properties. Protein which are not endogenous or immunogenic to an animal can be chemically modified so as to make them more immunogenic. Also, modified antigens useful for fertility control can be produced by chemical modification of zona pellucida or sperm antigens. These modified polypeptides. antigens and modified antigens are desirably administered in the form of a vaccine having a vehicle comprising a mixture of mannide monooleate with Squalene and/or Squalene.
The present invention describes novel applications of an oil formulation rich in carotenoids and poly-unsaturated fatty acids (PUFA) for skin care, lip care and cosmetic use. The formulation contains natural oil extract of  Momordica cochinchinensis  Spreng also known as gac, spiny melon, Redmelon™. The formulation contains carotenoid antioxidants (beta-carotene and lycopene), pro-vitamin A carotenoid (alpha and beta-carotene), and vitamin E. In addition, the formulation contains omega-3, omega-6, omega-9 fatty acids, the essential fatty acids important in enhancing skin integrity, elasticity. The oil-based formulation helps skin to retain water, Carotenoids in the formula protects skin from oxidative damage. The novelty of this invention is in the mixture of antioxidants, retinol and essential fatty acids to deliver a stable, bioavailable and nutritious composition for skin care. In addition, the formulation provides vitamin E and retinol beneficial in skin therapeutic and cosmetic applications.
PROBLEM TO BE SOLVED: To provide a composition for facilitating blood circulation, which promotes excretion of body wastes. SOLUTION: The composition is comprised mainly of mineral salts and pyrolignous acid. The body wastes are excreted from the body by the salting-out effect of the mineral salts. At the same time, pyrolignous acid facilitates blood circulation by its bloodstream facilitating effect and promotes excretion of the body wastes from the body. In addition, pyrolignous acid, being an organic acid, makes the composition acidulous, which condition is nearly the same as skin. In such acidulous condition, the salting-out effect of the mineral salts is promoted.
In randomised patients in control arm was initially performed forceps biopsy (6 samples) with 5.2F or 7.5F forceps and cosequently cryobiopsy (3 samples). Both sampling techniques were performed during one procedure of percutaneous transhepatic drainage under fluoroscopic control.
PURPOSE:To improve protective capacity for a core material and to improve also safety for human body by mixing an aq. dispersion of microcapsules having a shell comprising polyvinyl alcohol with an aldehyde having a specified solubility, and allowing the shell to react with the aldehyde in acidic condition. CONSTITUTION:An aq. dispersion contg. microcapsules having a shell consisting of polyvinyl alcohol and an aq. soln. contg. 8-50wt.% electrolyte, is mixed with an aldehyde having >=10% solubility in water at 20 deg.C. Thus, the shell of microcapsules are improved by causing a reaction in acidic condition. Preferred polyvinyl alcohol is that contg. 50wt.% polyvinyl alcohol component in the polymer. Preferred amt. of the aldehyde to be added is 0.3-10times by weight of the polyvinyl alcohol, and the reaction is preferred to be carried out at 0.5-4.5pH.
The present invention relates to a medicinal preparation containing raw material and a reaction product with blurry structure, particularly to liquid medicine for curing burns or scalds and a preparation method of the liquid medicine. The present invention is the liquid medicine prepared by that 50 to 80 grams of live earthworms are added to 20 to 49 grams of cane sugar to generate solution, and then, the solution is mixed with 0.5 to 1 gram of borneol. The preparation method comprises: the ingredients are proportionally mixed; the live earthworms and the cane sugar are added into a container; generated milk white solution is filtered, and the borneol is put in the solution to form the medicinal preparation. The present invention can be used for patients with burns and scalds of the low degree and the high degree and electric shock burns. No skin graft, no packing and no wound surface disinfection are required, and internal diseases are cured by external applied medicine. Therapeutic action is exerted by the infiltration and the absorption of skin mucosa.
Dexamethasone 0.01% (0.5mg/5 mL) oral rinse solution in post allogeneic hematopoietic stem cell transplant participants. Rinse oral cavity three times daily for two minutes with ten milliliters then expectorate. Complete for three months duration.
The present invention relates to a tablet for treating gastritis. The present invention is characterized in that the compound preparation is composed of gentamycin sulfate, procaine hydrochloride and vitamin B12. Each tablet contains 20 thousand to 40 thousand international units of gentamycin sulfate, 0.1 to 0.2g of procaine hydrochloride and 50 to 100 mu g of vitamin B12. Starch and hydroxymethylstarch are used as main auxiliary materials and granulated, and magnesium stearate is used as flow assisting agents to compress the materials into tablets; 5% IV gastro-soluble acrylic resin, 2% hydroxypropyl methyl cellulose, etc. are used as main auxiliary materials for instant gastro-soluble film coatings. The tablet of the present invention has the advantages of reasonable formula, accurate curative effect, high safety, fast effect, obvious improvement on symptoms, wide source of raw materials and low price.
The subjects will take 4 capsules/day during 6 months. The placebo capsule contained 500 mg of sunflower oil with 3.75 U vitamin E.
Survivors of sex trafficking (SST) who were living in a residential facility participated in this project by receiving occupation-based programming to address limitations in executive function skills over the course of the 8-month project. Sessions were held twice-monthly for an hour duration at each session.
After control of bleeding in teeth allocated to the control group i-PRF is to be injected first. The i-PRF will be injected into the root canal to a level 3 mm below the cementoenamel junction (CEJ) then a layer of premixed bioceramic putty is to be added for coronal sealing.
Inflammatory reactions after acute intracerebral hemorrhage (AICH) contribute significantly to a poor prognosis. Liangxue Tongyu Prescription (LTP) has been proven to be clinically effective in treating AICH. Numerous studies have shown that LTP suppresses brain inflammatory damage in AICH, while the internal mechanisms underlying its action remain unclear. The aim of this study was to verify the anti-inflammatory effects of LTP on an AICH rat model and investigate the potential mechanisms. The AICH rat models were created by injecting autologous blood into the right caudate nucleus. LTP markedly decreased cerebral hematoma and brain water content and recovered from neurological deficits. Meanwhile, LTP prevented microglial activation and reduced the inflammatory reaction caused by pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6). Notably, the expression of cholecystokinin octapeptide (CCK-8) in the brain and intestine was increased by LTP or CCK-8 treatment. LTP further suppressed nuclear factor kappa B (NF-κB) in the brains of rats with AICH. Moreover, LTP increased the protein and mRNA expression of Occludin and Claudin-1 in the intestine and decreased the levels of lipopolysaccharide (LPS) and diamine oxidase (DAO) in serum. Furthermore, the results showed that LTP increased the protein and mRNA expression of Claudin-5 and zonula occludens-1 (ZO-1) in the brain. CCK-8 receptor antagonists increased the expression of NF-κB and the concentration of pro-inflammatory cytokines. These findings suggested that LTP attenuated neuroinflammation by increasing CCK-8 in the brain and intestine, and its mechanism might be related to alterations in the gut-brain axis (GBA).
Somnolence was a commonly reported adverse event reported in patients treated with quetiapine fumarate especially during the 3-5 day period of initial dose-titration. In schizophrenia trials, somnolence was reported in 18% (89/510) of patients on quetiapine fumarate compared to 11% (22/206) of placebo patients. In acute bipolar mania trials using quetiapine fumarate as monotherapy, somnolence was reported in 16% (34/209) of patients on quetiapine fumarate compared to 4% of placebo patients. In acute bipolar mania trials using quetiapine fumarate as adjunct therapy, somnolence was reported in 34% (66/196) of patients on quetiapine fumarate L compared to 9% (19/203) of placebo patients. In bipolar depression trials, somnolence was reported in 57% (398/698) of patients on quetiapine fumarate compared to 15% (51/347) of placebo patients. Since quetiapine fumarate has the potential to impair judgment, thinking, or motor skills, patients should be cautioned about performing activities requiring mental alertness, such as operating a motor vehicle (including automobiles) or operating hazardous machinery until they are reasonably certain that quetiapine fumarate therapy does not affect them adversely. Somnolence may lead to falls.