anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
PURPOSE:To obtain a depilatory agent having excellent protecting effects on skin, improving surface state of skin, forming beautiful skin, containing essence extracted from fruit of Citrus Junos Siebold with an aqueous solution of ethanol. CONSTITUTION:A depilatory agent blended with 2-25% alcohol-containing essence obtained by extracting fruit of Citrus Junos Siebold with an aqueous solution of ethanol. 20-40% aqueous solution of ethanol is preferable as the extracting solution. The extracted solution has 2.0-3.0% essence solid substance content, ethanol solution is evaporated from the extracted solution into solid substance once, the solid substance is added to the depilatory agent, or made into a concentrated solution or diluted with 20-40% ethanol solution and added to the depilatory agent in the above-mentioned ratio. The extracted solution does not required an antiseptic when preserved as it is but requires one when the alcohol is evaporated and the extracted solution is made into the solid substance. The extracted essence will not cause skin irritation and contact allergy.
The study was conducted on 10 female (Group 1) and 10 male (Group 2) university students. The vertical jump height (VJH) of the individuals who agreed to participate in the study was measured with a wireless jumping platform. After the initial evaluations, lower extremity static stretching exercises targeting the M. Gastrocnemious and M. Hamstring muscles were applied to the participants in both groups. The VJH of the participants was re-evaluated immediately after the application. Both pre-post evaluations and female-male comparison evaluations will be performed for the statistical analysis of the data.Statistical analysis will be performed with SPSS 24.0 program. If the data is parametric, paired sample t-test will be used for within-group evaluation; independent sample t-test will be used for between-group evaluation. If the data is non-parametric, Wilson test will be used for within-group evaluation and Mann Whitney U test will be used for between-group evaluation.
Biphasic insulin Aspart 30 (Colorless transparent liquid, 100u/mL, 3ml each, Novo Nordisk), subcutaneous injection, starting at a dose of 0.2-0.4 IU/kg, or 10～12 IU/d assigned in pre-breakfast and pre-supper in a 1:1 ratio. The adjustment of insulin dose is instructed to achieve an optimal balance between glycaemic control and risk of hypoglycaemia as dictated by best clinical practice, titrated to glucose targets of fasting plasma glucose (FPG) and pre-supper \<7 mmol/L.
Patients receive oral suberoylanilide hydroxamic acid (SAHA) twice daily on days 1-14. Treatment repeats every 21 days for 4 courses in the absence of disease progression or unacceptable toxicity. Patients are then evaluated for disease response. Patients achieving a complete response receive an additional 2 courses of SAHA. Patients achieving stable disease or a partial response receive 4 additional courses of SAHA.After completion of study treatment, patients are followed within 4 weeks.
The present invention relates to a kind of external Chinese medicine ointments for treating goat.Prior art blank, the external Chinese medicine ointment of this treatment goat are filled to fill up, raw material includes the dry Asian puccoon of the dry campanulaceae of 6 parts by weight, the dry lemon-grass of 2 parts by weight, the dry elscholtiza of 2 parts by weight, the extra dry red wine flower of 1 parts by weight, 1 parts by weight, and preparation method is as follows：1. crushes raw material, mixing.2. is added 100 parts by weight water and is heated to 100 DEG C in the case where keeping stirring or boils, and is kept for 20 minutes.3. the material that 2. gained boils is ground into mass by with liquid ball mill.4. after mass is naturally cooling to 30 ± 2 DEG C by, pouring into one in fermentation tank with dissection.5. saccharomyces cerevisiae and sugar is added to fermentation tank in, sealed after being stirred, within the scope of 30 ± 2 DEG C, continuing fermentation 10 days；It is eventually adding sodium hydrogensulfite, terminates fermentation；Xanthans is added, adjusts consistency.The present invention without any toxicity and side effects, is suitble to gout patients to use.
A composition for the treatment of acne includes hydrolyzed  psoralea corylifolia,  containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In various implementations, the composition is a water-based acne gel or a water-based cleanser. In a specific implementation, a composition includes Bakutrol™, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid, benzoyl peroxide, tretinoin, retinol, tazarotene, or an antibiotic, or a combination of these. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.
PURPOSE:To provide a warming material capable of lowering the combustion temperature of moxa to apply moxa cautery to skin without burning the skin, by adding a mineral powder component comprising zirconium fine powder and/or silica fine powder and feldspar fine powder to the moxa. CONSTITUTION:80-60pts.wt. of moxa and 20-40pts.wt. of mineral powder component comprising zirconium fine powder and/or silica fine powder and feldspar fine powder are stirred with a mixer or hand to homogeneously disperse and compound the components to provide the objective warming material. Since the mineral powder component radiates far infrared rays when fired, a warming effect is transmitted to the inner deep portions of a body as well as to the skin surface thereof. The moxa cautery gives a warming irritation directly or indirectly to the body, thereby being a treating method for activating the natural curing power of the body to accelerate the recovery of the body from diseases. The moxa cautery to healthy men activates the recovery of fatigue, the acceleration of blood circulation and the work of stomachs and intestines. Effects such as the remission of nervous or muscular pain are obtained.
In the coached group (CG), patients received standard support completed by 5 sessions (day 3, 10, 30, 60, 90 with equipment at home) of telephone-based counselling session by competent staff. Sessions were performed by a qualified person in education, qualifies by a university degree (Paul Sabatier University, Toulouse, France). The dates of phone calls were planned with the patient availabilities.
Topically treatment with AR/101+Standard of Care once daily for up to 21 days. Daily treatment will include application of AR/101 drug to the wound and coverage with dressing (SoC). Subjects who are scheduled for an elective abdominoplasty at the practice of the principal investigator will have superficial split thickness wounds created on their abdomen according to protocol about 4 weeks prior to their scheduled abdominoplasty. A total of 8 split thickness (5X5 cm, 0.0254 mm in thickness) wounds will be distributed on the abdomen between the umbilicus and the suprapubic hairline. 4 of the wounds will be treated with AR/101.
Pediatric patients who have undergone liver transplantation and have recovered normally typically undergo liver biopsy around 3 to 5 years postoperatively and around 10 years postoperatively to evaluate the presence of potential subclinical rejection. This assessment guides the long-term application of immunosuppressive medications.
Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a nonsteroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greater risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state.

Renal pelvic transitional epithelial hyperplasia, a spontaneous change occurring with variable frequency, was observed with increased frequency in treated male rats in a 2-year chronic study.

Caution is recommended in patients with pre-existing kidney disease.
A pharmaceutical composition for oral administration comprises: a core comprising hydrocortisone and a carrier, contacting the core is a layer comprising a delayed release polymer wherein the delayed release polymer is a pH sensitive enteric polymer and is a mixture of poly(methacrylic acid/methyl methacrylate) in a ratio of 1:1 and poly(methacrylic acid/methyl methacrylate) in a ratio of 1:2 to delay the release of hydrocortisone from the core. Preferably the ratio of the two polymers is 1:4 and forms about 6-7% w/w of the composition. The hydrocortisone may be present in or on the carrier together with a binding agent such as povidone which is preferably present at a concentration of between 0.5-4% w/w of the composition. The enteric polymer layer may comprise a plasticiser such a dibutyl sebacate which is preferably between 0.5-1.0% w/w of the composition. The hydrocortisone may be substituted for cortisone acetate. Preferably the composition is for use in the treatment of adrenal insufficiency, inflammatory conditions and depression.
FIELD: medicine. SUBSTANCE: method involves applying complex treatment of patient organism by nasal massage through mechanical action done with fingers on nose base along the lower edge on both sides in gradually moving the point of action towards the nose tip. Mechanical treatment is combined with breathing exercise course and yoga exercise course. Inhalation course is administered with garlic, radish and soda. Dry herbal species including eucalyptus leaf, plantain, yarrow, young nettle, nettle dioecious, camomile, fire weed, St. John's wort is given in the form of extraction and thermopsis, calcium gluconate, sweet cabbage juice, eucalyptus tincture are given as well. Hot baths and nose lavage are additionally administered. EFFECT: enhanced effectiveness of treatment course.
The general practitioner systematically delivers the screening kit with justification and modalities of realization at an even age between 50 and 74 years to the patient who comes to consult for whatever reason, who is at intermediate risk of colorectal cancer and who falls under the generalized screening. The practitioner is helped in his approach by an initial training in the identification of the age, delivery of a poster, a study sheet, stickers and goodies, sending a quarterly letter on the progress of the study and contact with the coordination team.
TheraDrive is a low-cost robotic system for post-stroke upper extremity rehabilitation. The system uses off-the-shelf computer gaming wheels with force feedback to help reduce motor impairment and improve function in the arms of stroke survivors. Preliminary results from various studies have shown that the original TheraDrive system lacked a robust mechanical linkage which could withstand the forces exerted by patients, lacked a patient-specific adaptive controller to deliver personalized therapy, and was not capable of delivering effective therapy to severely low-functioning patients. A new low-cost, high-force haptic robot with a single degree of freedom has been developed to address these concerns. This study has two purposes: first, to test the viability and usability of the new robot system alongside the original TheraDrive system; and second, to test if low-functioning patients benefit, and if so how much, from using force-feedback therapy as opposed to devices with zero impedance. This will be done by recruiting approximately 36 human subjects. Exercises will be performed by study subjects and an adaptive controller will monitor patient performance to ensure that exercises are difficult but doable, which is important for maintaining patient motivation. It is hypothesized that not only will the new system be viable, but that it will provide better robot-assisted therapy to a large variety of patients, especially low-functioning stroke survivors with hemiplegia.
7.2Amphetamine & Other Drugs Affected by Urine Acidification

Ascorbic acid may acidify the urine and lower serum concentrations of amphetamine by increasing renal excretion (as reflected by changes in amphetamine urine recovery rates). In case of decreased amphetamine efficacy discontinue ASCOR administration. Standard monitoring of therapy is warranted.

In addition, acidification of urine by ascorbic acid will alter the excretion of certain drugs affected by the pH of the urine (e.g., fluphenazine) when administered concurrently. It has been reported that concurrent administration of ascorbic acid and fluphenazine has resulted in decreased fluphenazine plasma concentrations. Standard monitoring of therapy is warranted.
Salts of formula (I): (where B = an N-contg. base cpd. or an alkali(ne earth) metal) metal equiv.). The N-contg. cpds. B are e.g., alkylamine, alkanolamine, alkylarylamine or cyclic amine. Pref. alkali(ne earth) metals are Li and Ca. Prepn. is by neutralising p-dihydroxybenzenedisulphonic acid with the base of cation B or with its salt with a weak acid giving double decompsn. between a salt of the acid and another cation and a salt of cation B and another acid. (I) are used as haemostatics well as agents against fragility of hair follicles.
Patient who are on both metformin 2g per day or metformin extended release 2g per day and gliclazide 320mg per day or gliclazide modified release 120mg per day. Subject will be required to fast overnight. Fasting insulin levels and plasma drug levels will be measured.
Chronic obstructive pulmonary disease (COPD) is a significant public health issue characterized by progressive and irreversible airflow limitation. The aim of this meta-analysis was to determine the association between changes in serum galectin-3 levels and COPD and to assess the relationship between serum galectin-3 levels and acute exacerbations of COPD (AECOPD). Relevant observational studies were retrieved from electronic databases, including PubMed, Web of Science, Embase, Wanfang, and China National Knowledge Infrastructure (CNKI). A random-effects model was used to combine the data, incorporating the influence of between-study heterogeneity. Twelve case-control studies were included. The pooled results showed a significantly higher serum level of galectin-3 in patients with COPD compared to controls (standardized mean difference [SMD] 0.60; 95% confidence interval [CI] 0.40 - 0.80; P < 0.001; I2 = 68%). Further meta-analysis suggested higher levels of serum galectin-3 in patients with AECOPD compared to those with stable COPD (SMD 0.33; 95% CI 0.20 - 0.46; P < 0.001; I2 = 0%). Subgroup analyses according to the mean age of the participants, the proportion of males, and study quality scores did not significantly change the results (P for subgroup differences all > 0.05). In conclusion, patients with COPD were found to have higher serum levels of galectin-3, with levels further elevated in patients with AECOPD compared to those with stable COPD.
PURPOSE: To control the level of nerve growth factor(NGF) of central nervous system by administering an effective amount of cytokine. CONSTITUTION: The NGF level of a central nervous system is controlled by administering an effective amount of a cytokine to increase the NGF synthesis, a cytokine to lower the NGF synthesis or a substance indirectly varying the NGF level by varying the cytokine level. The cytokine effective for increasing the NGF synthesis is e.g. interleukin-1, fibroblast growth factor, tumor growth factor αand β and platelet-originated growth factor, and the substance to vary the cytokine level is e.g. an IL-1 inhibitor such as glucocorticoid (e.g. dexamethasone). This procedure is effective for the treatment of nervous disorder caused by the damage of central nervous system by surgical operation, ischemia, sensitive tumor or a toxic agent, congenital learning disability and degenerative disorder of nerve, especially dementia such as Alzheimer's disease.
Cognitive Processing Therapy (CPT) is employed. Each patient will attend 12 individual sessions with the therapist. The sessions will be on the weekly basis. The standard manual of CPT (Resick et al., 2016) is going to be employed.
PURPOSE:To provide a CHUOKO plaster (a Chinese drug) for external use, applicable easily without staining clothes, etc., by compounding a plaster composed of a rubber-based adhesive substance with at least UKON (rhizoma of Curcuma longa), OUBAKU (bark of Phellodendron amurense), beeswax and a vegetable oil, and applying the obtained adhesive layer to a carrier. CONSTITUTION:A plaster composed of a rubber-based adhesive substance (e.g. natural rubber, butyl rubber, etc.) is compounded at least with UKON, OUBAKU, beeswax and a vegetable oil, and the obtained adhesive layer is applied to a carrier (e.g. paper, woven cloth, etc.) to obtain the objective drug for external application. Although CHUOKO has excellent effect to various purulent diseases, it is very difficult to use because of the clothes-staining problem caused by its high stickiness, and the necessity to be spread on cloth, etc. in use. The application has been extremely simplified by compounding a drug based on the composition of CHOKO to the plaster, and applying the plaster composition closely to a carrier. The amounts of the components are usually 300-3,000pts.wt. of vegetable oil, 10-120pts.wt. of UKON, 120-1,150pts.wt. of beeswax and 6- 60pts.wt. of OUBAKU per 100pts.wt. of the rubber-based adhesive substance.
NEW MATERIAL:The compound of formula I. USE:An antiulcer agent. PREPARATION:The objective compound of formula I can be produced by reacting a compound of formula II with an ajmaline derivative of formula II in the presence of an acid catalyst (e.g. hydrochloric acid) in an organic solvent (e.g. methanol) at 0-100 deg.C. The compound of formula II is synthesized from a tetrahydrocarboline derivative of formula IV and the compound of formula III is synthesized from a compound of formula V by reacting with a chloroformate and subsequently reducing with lithium aluminum hydride.
The aim of this prospective study is to collect data on patients with liver cirrhosis and to investigate the impact of acute kidney injury on sarcopenia and frailty in patients with liver cirrhosis. If patients agree to participate in this clinical trial, the patients' data (such as age, sex, height, weight, nutrition status \[RFH-NPT\], history of medication, laboratory findings, endoscopic findings, and radiologic findings) will be collected in a research database. Renal injury was measured using conventional and novel serum biomarkers (serum creatinine, cystatin-C, neutrophil gelatinase-associated lipocalin, kidney injury molecule 1, and interleukin-18. Sarcopenia was evaluated using skeletal muscle index on abdominal computed tomography. Frailty was measured using Liver Frailty Index. The research database will be updated to include data on patients' disease outcomes and follow-up care.
BACKGROUND: Atrial septal defect (ASD) is a common form of congenital heart disease. Although several genes related to ASD have been found, the genetic factors of ASD remain unclear. This study aimed to evaluate the correlation between 10 candidate single nucleotide polymorphisms (SNPs) and sporadic atrial septal defects.
METHODS: Based on the results of 34 individual whole exome sequences, 10 candidate SNPs were selected. In total, 489 ASD samples and 420 normal samples were collected. The 10 SNPs in the case group and the control group were identified through Snapshot genotyping technology. The χ2-test and unconditional regression model were used to evaluate the relationship between ASD and each candidate SNP. Haploview software was used to perform linkage disequilibrium and haplotype analysis.
RESULTS: The χ2 results showed that the FLT4 rs383985 (P = 0.003, OR = 1.115-1.773), HYDIN rs7198975 (P = 0.04621, OR = 1.003-1.461), and HYDIN rs1774266 (P = 0.04621, OR = 1.003-1.461) alleles were significantly different between the control group and the case group (P < 0.05). Only the association with the FLT4 polymorphism was statistically significant after adjustment for multiple comparisons.
CONCLUSION: These findings suggest that a possible molecular pathogenesis associated with sporadic ASD is worth exploring in future studies.
We may ask healthy subjects to return for up to four injection sessions for the study. The first injection session will consist of intradermal injection of ICG into the webspaces of the hand as done in our previous studies followed by NIR camera imaging. The second session will consist of intradermal gadolinium injection and intravenous (IV) iron contrast agent followed by MRI imaging approximately 1 week after the first session. The third session will occur at minimum eight weeks later and entail intra-articular ICG injection in order to evaluate drainage via the lymphatics. The MCP joints will be identified in the non-dominant hand and injected with ICG. Approximately one week later, the fourth session will compromise of intra-articular gadolinium injection and IV iron contrast to confirm lymphatic drainage. The MCP joints of the non-dominant hand will again be identified and injected with gadolinium.
Patients with brain metastases outside a 5-mm margin around either hippocampus and are eligible to this study will receive hippocampal avoidance whole brain radiotherapy 30 gray (Gy) in 10 fractions. The primary endpoint is Wechsler Memory Scale (Chinese) and cognitive abilities screening instrument (CASI) at 4 months.