anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
The invention discloses traditional Chinese medicine powder for treating trauma and a preparation method thereof. The traditional Chinese medicine powder is prepared from the medicinal raw materials of trillium tschonoskii maxim and refined white sugar according to a preparation method in pharmacopeia. The preparation method of the traditional Chinese medicine powder comprises the following steps of: cleaning, peeling and drying the medicinal raw materials in the formula except refined white sugar, refined grinding, subpackage and sterilization. The traditional Chinese medicine powder for treating trauma and a preparation method thereof provided by the invention have the beneficial effects that after clinic application for ten years, the powder has a definite curative effect of trauma hemostasis, pain stopping, inflammation diminishing and healing promotion. Clinic observation for many years shows that a new wound can heal and scab through one-time application of the traditional Chinese medicine powder in the case of no infection, no stitching is needed and no scars are left. The powder is remarkable in effect and convenient to use; manufacture process is very simple and does not need special equipment; and no toxic reactions are found after observation for many years.
The bipolar RF (BRF) probe will be inserted at the same area with TCRF. We use 2.5 watt and 3 sec for each point but will stop immediately if the burning color or sound are detected. Otherwise was the same with TCRF.
For the patients in this group, sociodemographic form, happiness questionnaire, and PSQI was applied as pretest in preliminary examination. The final examination was performed 1 month later (posttest) by using the same scale. For the patients in foot massage group, 30-min foot massage sessions (15 min for each foot, 3 sessions per week for 1 month) were performed in a special room of rehabilitation center, in a quiet atmosphere at suitable temperature and without environmental stimulants.
Since rocuronium bromide is primarily excreted by the liver, it should be used with caution in patients with clinically significant hepatic impairment. Rocuronium bromide 0.6 mg/kg has been studied in a limited number of patients (n=9) with clinically significant hepatic impairment under steady-state isoflurane anesthesia. After rocuronium bromide 0.6 mg/kg, the median (range) clinical duration of 60 (35 to 166) minutes was moderately prolonged compared to 42 minutes in patients with normal hepatic function. The median recovery time of 53 minutes was also prolonged in patients with cirrhosis compared to 20 minutes in patients with normal hepatic function. Four of 8 patients with cirrhosis, who received rocuronium bromide 0.6 mg/kg under opioid/nitrous oxide/oxygen anesthesia, did not achieve complete block. These findings are consistent with the increase in volume of distribution at steady state observed in patients with significant hepatic impairment [see Clinical Pharmacology (12.3)]. If used for rapid sequence induction in patients with ascites, an increased initial dosage may be necessary to assure complete block. Duration will be prolonged in these cases. The use of doses higher than 0.6 mg/kg has not been studied [see Dosage and Administration (2.6)].
PURPOSE: To obtain a cosmetic comprising an ascorbic acid-contg. anhydrous composition and an alkaline agent-contg. aqueous composition, and intended for its delivery to the skin after stably preserving the ascorbic acid while avoiding irritation. CONSTITUTION: This cosmetic comprises an anhydrous composition containing 0.001-50 wt.% ascorbic acid and 0.01-99 wt.% of a pharmaceutically acceptable carrier (e.g. glycerol) and an aqueous composition containing 0.1-10 wt.% of an alkaline agent (e.g. triethanolamine) for raising the pH of the anhydrous composition and 60-95 wt.% of water. This cosmetic is in such multicompartment dispenser form as to separately hold both the compositions respectively into the different compartments of the dispenser. The weight ratio of the aqueous composition to the non-aqueous composition is (10:1) to (1:10), optimally, 1:1. This cosmetic enables active ascorbic acid to be delivered to the skin in good infiltrativity and transparency.
Pediatric patients with glioma who are positive for the H3 K27M mutation (positive testing in CLIA laboratory) and have completed at least one line of prior therapy. Evidence of progression is not required so that ONC201 may be administered to patients in the maintenance setting or to patients with recurrent/refractory disease.
The present invention discloses a crocodile ball food, relates to the crocodile ball food which can prevent and cure tumors, and provides the crocodile ball food which can prevent and cure tumors. The c crocodile ball food consists of the following raw materials in parts by weight: 100 parts of crocodile meat, 10-30 parts of pimpinella diversifolia fluid extract, 20-30 parts of starch, 1-5 parts of edible salt, and 8-20 parts of clear water. The pimpinella diversifolia fluid extract is prepared from 100 parts by weight of the pimpinella diversifolia. The crocodile meat has efficacies of nourishing heart and moistening lungs, supplementing blood and strengthening bones, supplementing kidney and solidifying essence, and dispelling evils and removing dampness. The pimpinella diversifolia is used to prepare the crocodile ball food which can prevent and cure tumors, has functions of preventing bacteria and viruses, and inhibiting tumors. activity, and is suitable for daily consumption of general consumers to prevent tumor diseases and also suitable for auxiliary health care for patients with tumors.
A system comprising for communication medical data includes a patient data component, a provider component, a session component, an authorization component, and a communication component. The patient data component is configured to store patient medical data corresponding to one or more patients. The provider component is configured to store destination information corresponding to a plurality of health care providers that can receive the patient medical data from the system. The session component is configured to establish and validate communication with a first patient via a remote device. The authorization component is configured to receive, from the remote device, a message indicating authorization from the first patient to send the medical data for the first patient to a first health care provider. The communication component is configured to send the medical data for the first patient to the destination information corresponding to the first health care provider.
Study DE020 was a multicenter, open-label continuation study for patients with rheumatoid arthritis who had participated in a prior Phase 1, 2, or 3 adalimumab study in the United States or Canada, had a favorable safety and efficacy profile when treated with adalimumab, and met the eligibility criteria for the continuation study. Participants received subcutaneous injections of adalimumab every other week (eow) or monthly based on the adalimumab regimen received in the prior study (i.e., participants who received monthly dosing in the prior study began the continuation study on monthly dosing; all other participants began adalimumab dosing at eow intervals). Participants who maintained an American College of Rheumatology 50% (ACR50) response for 2 consecutive visits could have their dosing interval lengthened to a monthly dosing schedule. Safety and efficacy data were collected over 520 weeks (10 years). Both safety and efficacy data were analyzed using all participants who received at least 1 dose of open-label adalimumab in the 10-year continuation study DE020 (the Full Analysis Set, n=846). Three patients who entered the continuation study but were never dosed were excluded from all analyses.
Men in Sub-Saharan Africa are less likely to test for HIV, initiate ART, and more likely to initiate ART at later stages of disease. Achieving epidemic control requires immediate, concentrated effort to engage this largely unreached population. Index partner testing, whereby partners of HIV-positive clients are refereed for HIV testing, is critical to identifying undiagnosed men and has been adopted as a national policy by the Malawi Ministry of Health because of its high acceptability and its dramatic increase on HIV testing uptake. Two overarching barriers keep HIV-positive men from accessing ART services: 1) Lack of male-friendly services, and 2) harmful gender norms. Home-based ART may improve ART initiation and retention among male partners who test HIV-positive through Index HIVST. We will pilot an intervention that provides home-based ART initiation and home-based continuation for male partners identified as HIV-positive through Index HIVST for 3-months, followed by assisted linkage to facility-based care at 4-months. This intervention offers opt-out ART and in-depth, male-specific counseling for 3-months before linking men to facility based care. We will directly compare home-based ART to facility-based ART, whereby a health care worker will conduct a home-visit with HIV+ male partners to provide confirmatory HIV testing and immediate assisted linkage to a nearby facility for facility-based ART initiation and continuation.
Animals routinely encounter environmental (e.g., high temperatures and hypoxia) as well as physiological perturbations (e.g., exercise and digestion) that may threaten homeostasis. However, comparing the relative threat or "disruptiveness" imposed by different stressors is difficult, as stressors vary in their mechanisms, effects, and timescales. We exploited the fact that several acute stressors can induce the loss of equilibrium (LOE) in fish to (i) compare the metabolic recovery profiles of three environmentally relevant stressors and (ii) test the concept that LOE could be used as a physiological calibration for the intensity of different stressors. We focused on Etheostoma caeruleum, a species that routinely copes with environmental fluctuations in temperature and oxygen and that relies on burst swimming to relocate and avoid predators, as our model. Using stop-flow (intermittent) respirometry, we tracked the oxygen consumption rate (MO2) as E. caeruleum recovered from LOE induced by hypoxia (PO2 at LOE), warming (critical thermal maximum, CTmax), or exhaustive exercise. Regardless of the stressor used, E. caeruleum recovered rapidly, returning to routine MO2 within ~3 h. Fish recovering from hypoxia and warming had similar maximum MO2, aerobic scopes, recovery time, and total excess post-hypoxia or post-warming oxygen consumption. Though exhaustive exercise induced a greater maximum MO2 and corresponding higher aerobic scope than warming or hypoxia, its recovery profile was otherwise similar to the other stressors, suggesting that "calibration" to a physiological state such as LOE may be a viable conceptual approach for investigators interested in questions related to multiple stressors, cross tolerance, and how animals cope with challenges to homeostasis.
HILT group received HILT 3 sessions per week for 3 weeks in addition to the therapeutic exercise program applied 5 sessions per week for 3 weeks. HILT was performed by a single physiotherapist experienced in using a laser device. In the HILT group, the device was used on the rotator cuff muscles in two stages: phase I and phase II. Pulse method was used in phase I for analgesic effect. For the biostimulation effect, the continuous wave method was used in phase II. In the next five sessions, biostimulation effect was applied using 7W power. A dose of 100 J/cm was applied longitudinally to the rotator cuff muscles area for a total energy of 2500 J for 25 minutes and 57 seconds up to 25 cm.
Corneal deposits and retinal disturbances, including those of the macula, have been observed in some patients who had received prolonged therapy with TIVORBEX. Be alert to the possible association between the changes noted and TIVORBEX. It is advisable to discontinue therapy if such changes are observed. Blurred vision may be a significant symptom and warrants a thorough ophthalmological examination. Since these changes may be asymptomatic, ophthalmologic examination at periodic intervals is desirable in patients receiving prolonged therapy. TIVORBEX is not indicated for long-term treatment.
Fecal microbiota via enema at Month 1, 2, 3. 4, 5 and month 6 along with stool, urine and blood collection. At months 7, 8, 9, 10, 11 and 12 only stool, urine and blood collection.
The invention relates to the field of bioorganic chemistry, pharmaceutical chemistry, and drug technology and concerns a method for preparing biologically active substances, possessing anti-giardiasis and anti-opisthorchiasis activity, from vegetable raw material. The aim of the invention is a method for preparing ecologically pure extract of Saussurea salsa (Pall.) Spreng., which possesses anti-giardiasis and anti-opisthorchiasis activity, which can be applied in medicine as phytoproduct with wide spectrum of action. Technical result of the disclosed invention is achieved by application of an ecologically safe method for preparing dry extract of Saussurea salsa (Pall.) Spreng. with quantitative content of active substance - sesquiterpene lactone cinaropicrine (2.2-2.61%).
Determine if the immunogenicity of oral typhoid can be enhanced in children by introducing zinc supplementation: Our recent studies on the interactions of oral cholera vaccine with breast milk and zinc provide some basis for improving immunogenicity, but additional work is needed to improve many of the oral vaccines. In this study we also plan to evaluate if the immune response to Cholera and Vivotif can be enhanced by supplementation with zinc using methods described earlier. We would like to study children, 2-5 years of age for this purpose.
OBJECTIVE: Same day discharge is safe after minimally invasive gynecology oncology surgery. Our quality improvement peri-operative program based on enhanced recovery after surgery principles led to an increase in same day discharge from 30% to 75% over a 12 month period. Twelve months after program implementation, we assessed the sustainability of same day discharge rates, determined post-operative complication rates, and evaluated factors affecting same day discharge rates.
METHODS: A retrospective chart review was conducted of 100 consecutive patients who underwent minimally invasive surgery at an academic cancer center from January to 2021 to December 2021. This cohort was compared with the active intervention cohort (n=102) from the implementation period (January 2020 to December 2020). Same day discharge rates and complications were compared. Multivariable analysis was performed to assess which factors remained associated with same day discharge post-intervention.
RESULTS: Same day discharge post-intervention was 72% compared with 75% during active intervention (p=0.69). Both cohorts were similar in age (p=0.24) and body mass index (p=0.27), but the post-intervention cohort had longer operative times (p=0.001). There were no significant differences in 30-day complications, readmission, reoperation, or emergency room visits (p>0.05). There was a decrease in 30-day post-operative clinic visits from 18% to 5% in the post-intervention cohort (p=0.007), and unnecessary bowel prep use decreased from 35% to 14% (p<0.001). On multivariable analysis, start time (second case of the day) (OR 0.06; 95% CI 0.01 to 0.35), and ward narcotic use (OR 0.12; 95% CI 0.03 to 0.42) remained associated with overnight admission.
CONCLUSION: Same day discharge rate was sustained at 72%, 12 months after the implementation of a quality improvement program to optimize same day discharge rate after minimally invasive surgery, while maintaining low post-operative complications and reducing unplanned clinic visits. To maximize same day discharge, minimally invasive gynecologic oncology surgery should be prioritized as the first case of the day, and post-operative narcotic use should be limited.
Pediatric oncohematological patients frequently require PICU admission during their clinical history. The O-PEWS is a specific score developed to predict the need for PICU admission of oncohematological children. This study aimed at i) describing the trend of the O-PEWS in a cohort of patients hospitalized in the Pediatric Oncohematology ward and transferred to the PICU of Padua University Hospital, measured at different time-points in the 24 hours before PICU admission and to evaluate its association with mortality and presence of organ failure; ii) investigating the association between the recorded O-PEWS, and PIM3, number of organ failure and the need for ventilation, dialysis and inotropes. This retrospective single-center study enrolled oncohematological children admitted to the PICU between 2017 and 2021. The O-PEWS, ranging between 0 and 15, was calculated on the available medical records and the TIPNet-Network database at 24 (T-24), 12 (T-12), 6 (T-6) and 0 (T0) hours before PICU admission. RESULTS: 101 PICU admissions, related to 80 children, were registered. During the 24 hours prior to PICU admission, the O-PEWS progressively increased in all the patients. At T-24 the median O-PEWS was 3 (IQR 1-5), increasing to a median value of 6 (IQR 4-8) at T0. The O-PEWS was positively associated with mortality, organ failure and the need for ventilation at all the analyzed time-points and with the need for dialysis at T-6. The O-PEWS appears as a useful tool for predicting early clinical deterioration in oncohematological patients and for anticipating the initiation of life-support treatments.
The indications for cochlear implantation have expanded over time due to evidence demonstrating identification and implantation of appropriate cochlear implant (CI) candidates lead to significant improvements in speech recognition and quality of life (QoL). However, clinical practice is variable, with some providers using outdated criteria and others exceeding current labeled indications. As a results, only a fraction of those persons who could benefit from CI technology receive it. This document summarizes the current evidence for determining appropriate referrals for adults with bilateral hearing loss into CI centers for formal evaluation by stressing the importance of treating each ear individually and a "revised 60/60 rule". By mirroring contemporary clinical practice and available evidence, these recommendations will also provide a standardized testing protocol for CI candidates using a team-based approach that prioritizes individualized patient care. This manuscript was developed by the Adult Cochlear Implantation Candidacy Task Force of the American Cochlear Implant Alliance using review of the existing literature and clinical consensus. LEVEL OF EVIDENCE: N/A Laryngoscope, 134:S1-S14, 2024.
The invention relates to a traditional Chinese medicine composition used for treating chronic obstructive pulmonary diseases (COPD), and a preparation method thereof. The traditional Chinese medicine comprises the raw materials of, by weight: 10-20 parts of radix pseudostellariae, 8-18 parts of common achyranthes, 9-12 parts of glossy privet fruit, 10-12 parts of creeping liriope, 4-9 parts of cordyceps, 10-16 parts of lumbricus, 9-10 parts of giant gecko, 18-25 parts of amur corktree bark, and 20-30 parts of dandelion. With the formula provided by the invention, the traditional Chinese medicine can be prepared into decoctions, powders or pills. The traditional Chinese medicine provided by the invention has a substantial effect in treating chronic obstructive pulmonary diseases. The traditional Chinese medicine composition provided by the invention is obtained on the basis of years of researches, and clinical observations of thousands of patients. The composition has a substantial clinical treatment effect. The composition has a positive effect in treating chronic obstructive pulmonary diseases, and has effects of substantially improving COPD symptoms and signs, increasing pulmonary ventilation, regulating immunologic functions, and the like.
The effects of overdosage are expected to be related primarily to albuterol sulfate. Acute overdosage with ipratropium bromide by inhalation is unlikely since ipratropium bromide is not well absorbed systemically after inhalation or oral administration. Manifestations of overdosage with albuterol may include anginal pain, hypertension, hypokalemia, tachycardia with rates up to 200 beats per minute, metabolic acidosis, and exaggeration of the pharmacologic effects listed in the Adverse Reactions section [see Adverse Reactions (6)]. As with all beta2-adrenergic agonist aerosol medications, cardiac arrest and even death may be associated with abuse.

Treatment of overdosage consists of discontinuation of COMBIVENT RESPIMAT together with institution of appropriate medical and supportive therapy. Dialysis is not appropriate treatment for overdosage of albuterol as an inhalation aerosol; the judicious use of a cardiovascular beta‑receptor blocker, such as metoprolol tartrate, may be indicated.
PROBLEM TO BE SOLVED: To obtain a heat transfer sheet which can be easily handled to dye hair without causing the dye to cling to the face or the like and also without causing the dyed hair to have coarse sensation by providing a layer containing the hair dyeing ingredient on a support. SOLUTION: This heat transfer sheet for hair dyeing is obtained by dissolving a hair dyeing ingredient together with a binder in a medium or dispersing its fine particles in a medium to prepare an ink, and by, e.g. spreading and drying the ink on a support (e.g. film of biaxially oriented polyethylene terephthalate) to form the layer containing the hair dyeing ingredient on the support. The permanent hair dyeing ingredients for the hair dyeing ingredient include a phenylenediamine, diaminopyridine, diaminoanthraquinone, polyphenol, aminophenol and their salts. The temporary hair dyeing ingredient(s) for the hair dyeing ingredient is at least one colorant selected from the group consisting of Red Nos. 221 and 226, Orange Nos. 203 and 401, Yellow Nos. 204 and 401, and Blue Nos. 201 and 403.