anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
BACKGROUND: Despite the importance of gait as a determinant of falls, disability and mortality in older people, understanding of gait impairment in COPD is limited. This study aimed to identify differences in gait characteristics during supervised walking tests between people with COPD and healthy controls.
METHODS: We searched 11 electronic databases, supplemented by Google Scholar searches and manual collation of references, in November 2019 and updated the search in July 2021. Record screening and information extraction were performed independently by one reviewer and checked for accuracy by a second. Meta-analyses were performed in studies not considered at a high risk of bias.
RESULTS: Searches yielded 21 085 unique records, of which 25 were included in the systematic review (including 1015 people with COPD and 2229 healthy controls). Gait speed was assessed in 17 studies (usual speed: 12; fast speed: three; both speeds: two), step length in nine, step duration in seven, cadence in six, and step width in five. Five studies were considered at a high risk of bias. Low-quality evidence indicated that people with COPD walk more slowly than healthy controls at their usual speed (mean difference (MD) -19 cm·s-1, 95% CI -28 to -11 cm·s-1) and at a fast speed (MD -30 cm·s-1, 95% CI -47 to -13 cm·s-1). Alterations in other gait characteristics were not statistically significant.
CONCLUSION: Low-quality evidence shows that people with COPD walk more slowly than healthy controls, which could contribute to an increased falls risk. The evidence for alterations in spatial and temporal components of gait was inconclusive. Gait impairment appears to be an important but understudied area in COPD.
Agent for treating malignant tumours consists of a filtered extract of four parts by wt. hops and one part by wt. valerian, in which a mixt. comprising six pts. Na soap, three parts K soap and one part soda together with distilled water has been dissolved so as to produce a liq. having a slight colour and faint odour of soap. This liq. is injected as body temp. into the blood and lymph ducts and is also administered orally if the patient can take it. Tumours can be cured, treated and inspected with a min. of interference by operation.
Most restaurants serve customers excess calories which significantly contributes to the obesity epidemic. This pilot study tested the feasibility and acceptability of offering customers standardized portions to reduce caloric consumption when dining out in three restaurants. Portions were developed to limit quantity of food served, with lunches and dinners ≤ 700 cal and breakfast ≤ 500 cal. Participating restaurants developed an alternative "Balanced Portions Menu." Training and instructions were provided with respect to the volume and weight of food to be plated following the standardized guidelines and providing at least one cup of vegetables per lunch/dinner. We invited local residents to help us evaluate the new menu. We monitored restaurant adherence to guidelines, obtained feedback from customers, and incentivized customers to complete dietary recalls to determine how the new menus might have impacted their daily caloric consumption. Of the three participating restaurants, all had a positive experience after creating the new menus and received more foot traffic. One restaurant that did not want to change portion sizes simply plated the appropriate amount and packed up the rest to-go, marketing the meals as "Dinner today, lunch tomorrow." Two of the restaurants followed the guidelines precisely, while one sometimes plated more rice than the three-fourths cup that was recommended. A significant number of customers ordered from the Balanced Portions menus. Two of the three restaurants have decided to keep offering the Balanced Portions menus indefinitely. Following standardized portions guidelines is both feasible for restaurants and acceptable to customers.
Using an Implantable Loop Recorder fo continuous rhythm monitoring and home follow-up. This will be combined with standard care procedure, which will include annual ECG, 24 hour Holter/5 day ECG monitoring and further investigation dependent on symptom status.
PURPOSE:To obtain the titled drink free from disagreeable odor and astringent taste and suitable as a health drink having excellent long-term preservability and palatability, by passing soya milk through an ultrafiltration membrane, acidifying the permeated liquid composed mainly of glycoside to precipitate proteins and imparting the obtained stock liquid with sweetness and flavor. CONSTITUTION:Whole soybeans are immersed in water, added with water, boiled and ground to obtain 'GO'. The GO is sterilized by heating e.g. at about 100 deg.C for about 3min and bean curd refuse is separated from the product to obtain soya milk having a definite concentration. The soya milk is passed through an ultrafiltration membrane e.g. at 60 deg.C and the permeated liquid having a definite concentration and composed mainly of a saponin which is glycoside component of soybean is acidified with citric acid, etc., to pH4.0-4.4 and, if necessary, the precipitated proteins are separated. The obtained stock liquid is added with a sweetener (e.g. sugar), sterilized, cooled, flavored e.g. with pineapple flavor and filled in a container.
PURPOSE:To make line cones easily visible and to enable an operator to easily make a high-accuracy plan by displaying the images of the section determined by a radiation source and the slice position assigned on scanno-side images together with the line cones. CONSTITUTION:The scan is energized by command information from an input device 48 and is thus instructed, by which the scanno-top image and plural sheets of the axial images by an X-ray CT are obtd. The scanno-top image is then displayed on a display 47 and a target shape is determined. An irradiation field and isocenter are assigned for this target shape. The transmission side images of an examinee P are thereafter reconstituted by using plural sheets of the axial images. The transmission side images are displayed by superposing the lines which are the measure for setting the slice position. MPR conversion is executed to display the MPR image and the line cones superposed thereon according to the assigned position when the slice position on a screen is assigned from the input device 48.
The COLON study is a multi-centre prospective cohort study among incident colorectal cancer patients recruited from 12 hospitals in the Netherlands. Patients with colorectal cancer are invited upon diagnosis. Upon recruitment, after 6 months, 2 years and 5 years, patients fill out food-frequency questionnaires; questionnaires about dietary supplement use, physical activity, weight, height, and quality of life; and donate blood samples. Diagnostic CT-scans are collected to assess cross-sectional areas of skeletal muscle, subcutaneous fat, visceral fat and intermuscular fat, and to assess muscle attenuation. Blood samples are biobanked to facilitate future analyse of biomarkers, nutrients, DNA etc. Analysis of serum 25-hydroxy vitamin D levels, B-vitamins and metabolomic profiles are scheduled. A subgroup of patients with colon cancer is asked to provide faecal samples before and at several time points after colon resection to study changes in gut microbiota during treatment. For all patients, information on vital status is retrieved by linkage with national registries. Information on clinical characteristics, including treatment-related toxicity and co-morbidity data, is gathered from linkage with the Netherlands Cancer Registry and with hospital databases or medical records. Hazard ratios will be calculated for dietary and lifestyle factors at diagnosis in relation to recurrence and survival. Repeated measures analyses will be performed to assess changes over time in dietary and other factors in relation to recurrence and survival.

The aim is to recruit at least 2000 patients with available data and blood samples.
It is an interventional study in which 60 chronic heart failure patients estimated to enroll according to random allocation and divided into two groups. The experimental group participants will involve in aquatic high intensity resistive training sessions. The participants in the intervention group will receive 1 h of supervised lower limb aquatic resistance training three times a week for 12 weeks, for a total of 36 training sessions. Resistance of exercises will be progressed with three different levels: barefoot, small fins and large resistance boots and the training leg will perform all the movements without contact with the pool walls or bottom i.e., non-weight bearing. The intervention will be completed in small groups of 6-8 subjects in a pool heated to 30-32 with two instructors: one ensuring intensity and the other full range of movement. Intensity of the training sessions will be set at "as hard and fast as possible" to ensure maximal muscle contraction. Full range of motion will be strictly controlled for to ensure optimal movement of synovial fluid and exposure of the whole cartilage to the low compressive and shear forces created by the muscle contraction and movement. Training intensity will be monitored using heart rate monitors (Polar Electro Ltd, Kempele, Finland), rate of perceived exertion (RPE) using the Borg 6-20 scale and number of repetitions achieved per movement.

The control group will maintain usual care and will be asked to continue their usual leisure time activities. They will be offered the possibility of participating in two sessions consisting of 1 h of light stretching and relaxation during the 3-month intervention period.
Artificial dermal scaffolds (ADSs) have great value in repairing deep skin defects. However, problems such as unsatisfactory angiogenesis and local dropsy or empyema often occur, resulting in delayed or even failed wound healing. Negative pressure wound therapy (NPWT) is an effective therapy to promote wound healing or shorten wound bed preparation time. Studies on whether it can improve the effects of ADSs have never been interrupted, and no consensus has been reached. In this study, an improved ADS was prepared by mesh technology, physicochemical experiments were conducted, cell adhesion and proliferation were assessed with the meshed ADS, and in vivo experiments were conducted to investigate the effects of meshed ADS or ADS combined with NPWT in repairing full-thickness skin defects. The results showed that the meshed ADS showed through-layer channels arranged in parallel longitudinal and transverse intersections. The cell experiments confirmed the good cytocompatibility. The in vivo experiments showed that there were no differences in the take rate or contraction of grafted skin among all experiment groups. The meshed ADS exhibited good histocompatibility, and there were no differences in tissue inflammation, dermal angiogenesis, or degradation among all groups. In addition, necrosis, dropsy, or empyema of the dermal scaffold were found in all experiment groups except for the meshed ADS + NPWT group, which showed better wound repair results, including fewer scaffold-related complications and satisfactory skin graft survival and wound contraction. In conclusion, this novel meshed ADS, which has a regular through-layer mesh structure and possesses stable physicochemical properties and good biocompatibility, combined with NPWT can ensure adequate subdermal drainage and reduce the risk of scaffold-related complications, thereby improving the quality and efficiency of wound repair, promoting a broader application of biomaterials, and helping physicians and readers implement more effective wound management.
FIELD: medicine, immunology, biotechnology. SUBSTANCE: invention elates to preparations used for treatment of cardiovascular system diseases and methods of their usage, in part, antithrombotic preparations prepared on the basis of monoclonal antibodies. Invention describes an antithrombotic preparation containing F(ab′) 2 -fragments of antibody FraMon in the concentration 1-5 mg/ml and also method of prophylaxis and treatment of thrombosis by intravenous administration of solution containing 1-5 mg of antibody FraMon per ml of F(ab′) 2 -fragments as bolus in the dose 0.25 mg/kg of weight, not less. Invention provides the development of effective antithrombotic preparation and method of prophylaxis and treatment of thrombosis, among them, in carrying out the coronary angioplasty. EFFECT: improved method of prophylaxis and treatment, enhanced and valuable properties of preparation. 4 cl, 4 tbl, 5 dwg
A gel capsule has embossed surface configurations that form, in relief, an imprinted design over the entire extent of its exterior surface. An apparatus and method for producing and/or manufacturing an imprinted gel ribbon that is useful in forming the gel capsule. The apparatus includes a spreader box and a rotatable casting drum. The spreader box holds a flowable gel, and has an opening through which the gel flows. The casting drum has an exterior cast surface that is provided with surface configurations in embossed relation thereon. In use, a receiving portion of the cast surface directly receives dispensed gel from the spreader box. The casting drum operatively rotates and drags the dispensed gel from the spreader box opening to solidify and form the gel ribbon, with the surface configurations forming, in relief, the imprinted design in one side of the ribbon.
Cricket is transformed over the years and dynamic of batting has changed. Gone are the days, when batters used to play the game with defensive mindset. Maintaining higher striker rate and arsenal of power hitting is the epitome of stroke play in limited overs cricket. After modernization of the game, several exercises are adapted to enhance the hitting capability of batsmen with conventional grip strength training but the effectiveness of nerve gliding exercises on handgrip strength is not utilized in cricketing population effectively as compared to tennis and squash players, where it improves the efficiency of wrist mobility in efficient stroke play. This study will compare the effects of the nerve gliding exercises and conventional grip strength exercises on handgrip strength, range of motion and performance of cricket batters. It will be a randomized clinical trial where non-probability convenience sampling will be used to recruit participants aged 18 to 35 years from various cricket academies in Lahore.

Participants will be randomized through lottery method and allocated into two groups. Group A (n=20) participants will receive nerve gliding exercises intervention, while Group B (n=20) will receive conventional grip strength exercises intervention. The Adjustable Hand Dynamometer for Grip Strength, Goniometer for Range of motion while Batting Tee Test for performance will be outcome measure tools. Data will be analyzed by SPSS version 26. The normality of the data will be conducted through the Shapiro-Wilk test; for between-group analysis, an independent t-test or Mann-Whitney will be conducted. Similarly, a paired t-test or Wilcoxon Rank test will be conducted for within-group analysis.
Following stroke walking dysfunction is prevalent. Traditional rehabilitation methods fall short of achieving desirable walking outcomes for most people who experience stroke. Robotic methods to assist walking, such as the Honda Walking Assist Device (HWA) Robot from Honda R \& D Americas Inc., are being explored as a means of improving the recovery of walking post stroke. Prior to examining the effectiveness of exoskeletal robots for walking recovery it is important to understand their effect on kinematic and muscle responses during walking. Kinematic and muscle responses at the hip during walking with the HWA were recently described.

The purpose of this study is to quantify the effect of walking with the HWA on body segments remote from the hip. These segments include knee, ankle, trunk and arm. The non-invasive measures used will include: walking kinematics (measurement of joint angles using cameras), muscle activity (Electromyography), ground reaction forces (detected by a force plate in the floor) and spatiotemporal characteristics (such as walking speed). Measures will be collected under three conditions: 1) walking at self-selected pace (control), 2) walking at self-selected pace with the HWA (4 Newton-meter assist mode for hip flexion and extension), 3) walking immediately following HWA use (aftereffect).
PURPOSE:A dentifrice, obtained by incorporating an N-type semiconductor capable of initiating photocatalytic reaction in a dentifrice ingredient consisting of a polishing agent and additive which are respectively inorganic compounds and having bacterial plaque decomposing action and germicidal effect on carious pathogenic germs at the same time. CONSTITUTION:A dentifrice obtained by incorporating <=20wt%, preferably 5-10wt% N-type semiconductor powder, e.g. titanium dioxide, capable of initiating photocatalytic reaction in a dentifrice ingredient consisting of a polishing agent of an inorganic compound, e.g. calcium hydrogenphosphate or calcium carbonate, and additive of an inorganic compound. The secondary treatment of the surface of the N-type semiconductor powder selected from supporting of platinum, reducing with hydrogen and sensitizing with a dyestuff further enhances the photocatalytic reaction. The germicidal action by OH radicals generated by irradiation of the N-type semiconductor powder with light in a state of contact with water in the oral cavity can be effectively enhanced by removing organic compounds.
A system for health management based on Internet of Things (IoT) and a method thereof are provided. The system includes a first-type IoT device, a second-type IoT device, a host server and a remote device. The first-type IoT device senses physiology status and sends a physiology information upload request. The host server receives the physiology information upload request and stores physiology information into a physiology information database. The second-type IoT device senses environment status and sends an environment information upload request. The host server receives the environment information upload request and stores environment information into an environment information database. The host server receives a report obtaining request and determines whether an access level is confirmed. If yes, the host server looks up the physiology information database and the environment information database to generate a health management report and sends it to a remote device.
PURPOSE: To obtain a polymerized allergen reduced in allergenicity while retaining the complete antigenicity of the allergen by mixing glutaric dialdehyde with a solution of a freeze-dried high-molecular weight ingredient of an active allergen extract under specific conditions. CONSTITUTION: A freeze-dried high-molecular weight ingredient from a homogeneous allergenic source material extracted with distilled water or an aqueous buffer solution is dissolved at 14-16mg/mL concentration in a phosphoric acid buffer solution at pH 7.4 and the resultant solution, as necessary, is clarified by centrifugation. The obtained transparent solution is then stirred at ambient temperature on a magnetic stirrer and a newly prepared 25% solution of glutaric dialdehyde is added thereto at 17-19μL ratio based on 1mL solution of the allergen. The resultant mixture solution is stirred at ambient temperature for 6hr and the reaction is terminated with glycine or other monoamino acids. A polymerized and a cross-linked product having >100,000 Da molecular weight is then obtained according to a dialysis with a tangenitial flow and/ore molecular sieving.  The prepared allergen is useful for treating pollen hay fever.
Control Group Patients in the control group will be provided with standard patient care and information. No application will be made. In summary, week 1 data collection forms will be filled out with the patients at the end of the first week. At the end of the 1st month, 1st month data collection forms will be filled out. At the end of the 3rd month, the study will be terminated by filling out the 3rd month data collection forms.
Chronic post thoracotomy pain syndrome (CPTPS) is a significant problem that has important effects on patients' daily activities. The severity of postoperative pain and the central sensitization associated with it are thought to play a role in the chronification of acute pain. Gabapentin has been shown to be effective in reducing acute post-surgical pain and treating CPTPS. There is conflicting data regarding its effects on the development of chronic post-surgical pain. Although pregabalin is similar to gabapentin there are only a few studies examining its use in the modification of post-surgical pain but evidence suggests that it might be effective. There are no studies examining the effect of pregabalin on the development of chronic post-surgical pain. Our hypothesis is that perioperative use of pregabalin will decrease the incidence of CPTPS. Our ultimate goal is to conduct a multi-center study assessing the effect of perioperative oral pregabalin on the development of CPTPS. Prior to this, we will carry out a prospective, randomized, placebo controlled, double-blinded pilot study to assess the feasibility, safety, and compliance associated with perioperative use of oral pregabalin in patients undergoing video assisted thoracotomy surgery (VATS) or open thoracotomy procedures.
Subjects who were not on anti-retroviral therapy (ART) during primary HIV-1 infection within the past 2 years. Subjects were given 3BNC117 and 10-1074 intravenously. Both 3BNC117 and 10-1074 were administered at 30 mg/kg dose level in separate bags of 250 mL normal saline in sequential administration. Subjects received 8 infusions of 3BNC117 and 10-1074 at weeks 0, 2, 4, 8, 12, 16, 20, and 24. The total duration of therapy was 24 weeks.
The purpose of this project is to evaluate maternal and infant outcomes based on race at UVA hospital. Health inequities are influenced by a combination of Social, Political, and Clinical determinants of health. Our hypothesis is that patients with minority status, particularly Black and Hispanic Americans, are more likely to have poor outcomes (based on various health metrics) compared to Non-Black, Non-Hispanic patients. We hypothesize further that it is likely not far off from national trends, which indicate that Black parturients are x4 more likely to die during childbirth, and Black children are 2.4x more likely to die before their first birthday than Non-Hispanic White children.

The EPIC database will be used on an institutional basis to obtain information and accessed by UVA statistician to perform the research described in this submission. The dataset does contain a few direct identifiers of medical record numbers, dates, and postal number. We anticipate that all statistical analysis will be performed at UVA by participating faculty/staff.