anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
The invention is a process of producing an herbal composition for diseases / illnesses namely Kidney Disease, Diabetes, Hemorrhoids and Intestine diseases. The remedy comprises of plants, plant parts and plant extracts namely, Ash Gourds (Benincasa hispida), Pepper (Piper nigrum), Aralu (Terminalia chebula), Bulu (Terminalia belerica), Liquorice (Glycryrrhiza glabra), Thippili (Piper longum), Nelli (Phylllanthus emblica), Fennel seeds (Nigella sativa), Cumin seeds (Cuminum cyminum), Ginger (Zingiber officinale) and Cane Sugar (Saccharum officinarum). Other contents are Ghee oil, Bee honey and cow/buffalo milk. The duration of the treatment is twenty days. The process emphasizes on using unglazed new clay pots, as their porous nature make them neutralize harmful chemicals while infusing beneficial chemicals in to the mixture. The poor hear conductive nature helps to spread the heat evenly and slowly through the mixture within. Through my experience over a decade, it has been proven that the medicines manufactured using the patent requested production method, not only provides quicker and better positive results compared to other existing treatments for concerned diseases / illnesses, it is also more healthier and friendlier to the environment.
A composition, comprising a first component --- Cistanche tubulosa extract and a second component --- an oxidized coenzyme (Q10) and/or a reduced coenzyme (QH). The weight ratio of the two components is: first component: second component = 0.67: 1 to 10: 1. The composition is a pharmaceutical composition, a food composition, a cosmetic composition, a health care product composition, or a feed composition. The pharmaceutical composition may be used for treating or preventing chronic fatigue syndrome. The food composition, cosmetic composition, health care product composition or feed composition may be used in at least one of the following situations: improving endurance or strength in exercising, enhancing or restoring physical strength, eliminating fatigue, preventing myocardial weakness, and improving cardiac weakness or cardiac performance.    Figure 1A
This invention relates to a sleep quality monitor system and a physiological signal monitor process. It is utilized for long term monitor sleep quality of the examinee at home. The sleep quality monitor system comprises at least a physiological signal sensor, a distributed data server, and at least one client computer. The physiological signal sensor connects with the distributed data server by means of wire or wireless. The distributed data server connects with the client computer mutually by Internet. The physiological signal sensor transmits the sensed physiological signal to the distributed data server to process, calculate, analyze and reserve. The client computer takes advantage of a physiological signal data process to proceed a further calculation and analysis the data reserved in the distributed data server. Furthermore, it appears to the assignee. Through the selective physiological signal sensor suited at home combining the distributed data server and Internet, the sleep quality system is suitable for long term monitoring sleep quality of the examinee at home.
OBJECTIVE: Obesity has become a major public health problem worldwide and particularly in China. This study examined the secular trend of overweight and obesity in China over the past 100 years.
METHODS: Nationwide data from the China Health and Nutrition Survey and the Chinese General Social Survey were used. A generalized binary mixed-effects model and a weighted quantile sum model were applied.
RESULTS: From 1909 to 2021, the prevalence of overweight and obesity remained stable from 1909 to 1944, experienced a smooth increase from 1945 to 1959 followed by a decline between 1960 and 1974, continued to rise after 1975, and peaked in 2003. The prevalence of overweight (obesity) among Chinese adults increased by 2.68 (6.21) times, from 20.65% (3.10%) in 1993 to 55.33% (19.26%) in 2021, and cohorts born during the Chinese Cultural Revolution (1960-1974) exhibited the lowest risk of overweight and obesity, associated with low protein intake and high physical activity. Cohorts born during the Reform and Opening-Up period (1975-2003) showed a high risk of overweight and obesity related to favorable socioeconomic status and rapid urbanization. Persistent differences by sex and emerging differences by socioeconomic status in overweight and obesity prevalence were captured.
CONCLUSIONS: Overweight and obesity trends in China have shown a distinctive increasing-decreasing-increasing pattern over the past 100 years. These patterns exhibit unique characteristics and are influenced by discernible social forces.
The invention belongs to the technical field of immune adjuvants and discloses an immune adjuvant which is a poly-phosphonitrile high-molecular polymer. A side chain of the high-molecular polymer is a para-sodium propionate phenoxyl and is 700000-1000000 units in molecular weight. The invention also discloses a method for preparing the immune adjuvants, a vaccine composition including the immune adjuvants and a preparation method thereof, and an application of the immune adjuvants in preparation of the vaccine composition. Through selection and screening of the side chain and the molecular weight of the poly-phosphonitrile high-molecular polymer, not only is hydrolysis rate of the poly-phosphonitrile high-molecular polymer effectively adjusted, but also an immune stimulation activity of the poly-phosphonitrile high-molecular polymer as the immune adjuvants is effectively improved. In addition, poly[bis(para-sodium propionate phenoxyl)]phosphonitrile is synthesized with tetrahydrofuran, instead of bis(2-methoxy ethyl)ether, as a solvent, so that the poly-phosphonitrile high-molecular polymer is low in raw material cost. The raw material is easy to obtain. The poly-phosphonitrile high-molecular polymer is simple in synthetic technology, is high in industrialization degree and is low in cost.
The participants of the wait-list control condition do not receive any new intervention during the intervention period of 8 weeks, but may continue any treatment that has already been started before, including medication. Participants in the wait-list control condition receive full access to the program after completion of the post-assessment.
A medical history documentation system and method for recording information relating to at least one of a designated patient's current medical condition, a physical examination, a diagnosis and a treatment plan is shown. The system includes a recording member having a plurality of discrete recording sections formed thereon programmed for recording information relating to the patient. The encoded indicia is communicated by a first person to a second person during a physical examination of the patient by the first person. An input member is used by the second person for recording medical information in the form of predetermined encoded indicia in applicable discrete recording sections of the recording member. A transcriber having a plurality of report section templates is used. Each report section template corresponds to a discrete recording section. Each of the report section templates comprise a plurality of optional text variable segments each of which are assigned to a selected one of the predetermined encoded indicia. The transcriber is operative to decode each one of the predetermined encoded indicia recorded on the recording member. An imaging device responsive to the transcriber prepares a patient's report specific to the designated patient. A method for using the system is shown.
Patients should be advised to measure Promethazine HCl Oral Solution with an accurate measuring device. A household teaspoon is not an accurate measuring device and could lead to overdosage, especially when a half a teaspoon is measured. A pharmacist can recommend an appropriate measuring device and can provide instructions for measuring the correct dose. 

Promethazine HCl Oral Solution may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Ambulatory patients should be told to avoid engaging in such activities until it is known that they do not become drowsy or dizzy from promethazine therapy. Pediatric patients should be supervised to avoid potential harm in bike riding or in other hazardous activities. 

The concomitant use of alcohol or other central-nervous-system depressants, such as sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers may enhance impairment (see WARNINGS-CNS Depression and PRECAUTIONS–Drug Interactions). 

Patients should be advised to report any involuntary muscle movements. 

Avoid prolonged exposure to the sun.
BACKGROUND: Adult survivors of childhood cancer are at elevated risk of morbidity and mortality compared to the general population, but their adherence to lifelong periodic surveillance is suboptimal. We aimed to examine adherence to surveillance guidelines for high-yield tests and identify risk factors for nonadherence in adult survivors of childhood cancer.
METHODS: In this retrospective, population-based cohort study, we used health care administrative data from Ontario, Canada, to identify adult survivors of childhood cancer diagnosed between 1986 and 2014 who were at elevated risk of therapy-related colorectal cancer, breast cancer, or cardiomyopathy. Using a Poisson regression framework, we assessed longitudinal adherence and predictors of adherence to the Children's Oncology Group surveillance guideline.
RESULTS: Among 3241 survivors, 327 (10%), 234 (7%), and 3205 (99%) were at elevated risk for colorectal cancer, breast cancer, and cardiomyopathy, respectively. Within these cohorts, only 13%, 6%, and 53% were adherent to recommended surveillance as of February 2020. During a median follow-up of 7.8 years, the proportion of time spent adherent was 14% among survivors at elevated risk for colorectal cancer, 10% for breast cancer, and 43% for cardiomyopathy. Significant predictors of adherence varied across the risk groups, but higher comorbidity was associated with adherence to recommended surveillance.
INTERPRETATION: Survivors of childhood cancer in Ontario are rarely up to date for recommended surveillance tests. Tailored interventions beyond specialized clinics are needed to improve surveillance adherence.
Patients in the experimental arm (the high flow nasal cannula group) will receive heated humidified high flow oxygen of 50L/min at FiO2 of 40% throughout the colonoscopy. A patient satisfaction survey will be administered after procedure.
Lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth experience more mental health problems than their heterosexual and cisgender peers. The purpose of the proposed mixed-methods study is to assess the feasibility, acceptability, and need for refinement of LGBTQ-affirmative cognitive behavior therapy for youth aged 12-17 years in New York, New Jersey, and Connecticut. This study will be the first to adapt the randomized controlled trial tested LGBTQ-affirmative CBT intervention for youth, and the first to deliver it in a virtual group format. Qualitatively, investigators will conduct structured post-treatment interviews to assess the feasibility, acceptability, and refinement of the intervention in this population. Quantitatively, investigators will assess the feasibility and acceptability of the intervention through analysis of indices like number of sessions attended, number of homework assignments completed, weekly treatment satisfaction ratings, and a post-treatment feedback survey. Investigators will also examine changes from pre- to post-treatment in youth's mental health symptoms, minority stress reactions, and emotional regulation and coping difficulties. These pilot data will be used to estimate the sample sizes needed for a future, larger trial of this treatment, as well as areas in which the treatment could be refined.
When the cervical dilatation was 3-4 cm, 30 minutes of warm compress and 10 minutes of perineal massage were performed. These two methods were applied when the cervical dilatation was 5-7 cm and 8-10 cm as well.
Background: The American Thoracic Society (ATS) convened an international, multidisciplinary panel to develop clinical practice guidelines for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD). Objective: To conduct a systematic review and evaluate the literature to determine the impact of treating patients with SSc-ILD with tocilizumab on prespecified critical and important outcomes determined by the ATS guideline panel. Data Sources: A literature search was conducted across MEDLINE, EMBASE, and Cochrane databases through June 2022 for studies using tocilizumab to treat patients with SSc-ILD. Data Extraction: Mortality and disease progression were determined to be critical outcomes of focus, with quality of life and adverse events important outcomes. Data on these outcomes were extracted and meta-analyses performed using the generic inverse variance method when possible. The Grading of Recommendations, Assessment, Development, and Evaluation Working Group method was used to assess the quality of evidence. Synthesis: The literature review resulted in five studies for inclusion. The absolute decrease from baseline in forced vital capacity (FVC) for the tocilizumab arm was 118 ml, 241 ml, and 129 ml less than the placebo arm at 24, 48, and 96 weeks, respectively, favoring tocilizumab. The mean decrease in FVC% predicted at 48 weeks was 6.50% less and the risk of decrease >10% was 66% less in the tocilizumab arm, whereas patients were 1.97 times more likely to have any increase in FVC% predicted if they received tocilizumab in place of placebo. When the placebo arm was given tocilizumab from 48 to 96 weeks, the mean change in absolute FVC was 54.90 ml less and the mean change in FVC% predicted was 1.30% less. For diffusing capacity of the lung for carbon monoxide (DlCO)% predicted, at 48 weeks there was 1.50% less change and from 48 to 96 weeks there was 5.40% less change in the tocilizumab arm. Quantitative Interstitial Lung Disease scores and Quantitative Lung Fibrosis scores at 48 weeks and modified Rodnan skin scores at 72 weeks all favored the tocilizumab arm, as did several adverse event parameters, including serious adverse events (mean difference, -27.40; 95% confidence interval, -30.10 to -24.70). The quality of evidence was very low grade. Conclusions: Tocilizumab use in patients with SSc-ILD is associated with less disease progression and a better toxicity profile than placebo. However, the quality of evidence is very low, and large prospective studies dedicated to assessing tocilizumab specifically for SSc-ILD are needed.
The participants are diagnosed coronary artery disease aged between 40- 80 and have no mental and physical disability to take part in research. The participants' demographic infos and clinical story were recorded. To evaluate exercise capacity we used the symptom-limited exercise test (ETT) and six minute walking test (6DYT). We evaluate the life quality by using Short Form-36 (SF-36).

All those evaluation tests are done before and after training. Participants are randomly divided into two groups, the first group took part in interval aerobic training (AAE) while the other group was joining in continuous training (SAE) three times a week during 6 weeks. In both groups, significant changes were found in ETT, test time and 6 DYT scores after the rehabilitation program (p\<0,05). But only AAE group have important statistical values comparing to SAE group on test time and 6DYT scores. After training SAE group showed significant statistical change in every SF-36 parameter, while AAE group showing significant values except energy/fatigue. AAE group have statistically significant changes comparing to SAE group on that parameters; physical function, role limitations due to physical function, role limitations due to emotional function and general health (p\<0,05). Consequently AAE is much more tolerable comparing to SAE and AAE is considered more effective in increasing some parameters. On the other hand, we observed that both training types can be used in cardiac rehabilitation safely.
The present disclosure shows that by combining pH-responsive bridging chitosan polymer chains and a tough hydrogel dissipative matrix one can achieve unprecedented ultra- tough adhesion to tissues (>2000J/m 2 ) in 5-10mins without covalent bond formation. The strong non-covalent adhesion was shown to be stable under physiologically relevant conditions and strongly influenced by chitosan molecular weight, molecular weight of polymers in the matrix, and pH. The adhesion mechanism relies primarily on the topological entanglement between the chitosan chains and the permeable adherends. The present disclosure also discloses dry polymer films to generate instant adhesion between hydrogel-hydrogel and hydrogel-elastomer surfaces. Unprecedented adhesive energies (>3000J/m 2 ) between alginate-polyacrylamide tough hydrogels were achieved instantaneously using an intermediate chitosan film, governed by pH change, H-bonding, and bridging polymer entanglement. Furthermore, this strategy also generates instant strong adhesion between acrylic elastomers and tough hydrogels with adhesion energy as high as 4000J/m 2 .
FIELD: medicine. ^ SUBSTANCE: invention belongs to medicine, notably to pharmaceutical composition for treatment and prevention of bacterial infections induced by gram-positive bacteria. Composition includes effective doses of cholanic acid or its salt, phosphatidylcholine and neutral lipids. Neutral lipids and phospholipids are associated in lipoprotein-like particles, which does not include proteins or peptides. ^ EFFECT: composition effectivity is caused by its ability to bind lipoteichoic acid of gram-positive bacteria, neutralising or preventing their pathogenic action. ^ 7 cl, 2 tbl, 1 ex
OBJECTIVE: This study aimed to compare the influence of inframalleolar (IM) P0/P1 on wound healing in bypass surgery vs endovascular therapy (EVT) in patients with chronic limb-threatening ischemia (CLTI).
METHODS: We retrospectively analyzed the multicenter data of patients who underwent infra-inguinal revascularization for CLTI between 2015 and 2022. IM P represents target artery crossing into foot, with intact pedal arch (P0) and absent or severely diseased pedal arch (P1). The endpoints were wound healing, limb salvage (LS), and postoperative complications.
RESULTS: We analyzed 66 and 189 propensity score-matched pairs in the IM P0 and IM P1 cohorts, respectively. In the IM P0 cohort, the 1-year wound healing rates were 94.5% and 85.7% in the bypass surgery and EVT groups, respectively (P = .092), whereas those in the IM P1 cohort were 86.2% and 66.2% in the bypass surgery and EVT groups, respectively (P < .001). In the IM P0 cohort, the 2-year LS rates were 96.7% and 94.1% in the bypass surgery and EVT groups, respectively (P = .625), and those in the IM P1 cohort were 91.8% and 81.5% in the bypass surgery and EVT groups, respectively (P = .004). No significant differences were observed between the bypass surgery and EVT in terms of postoperative complication rates in either the IM P0 or P1 cohorts.
CONCLUSIONS: Bypass surgery facilitated better wound healing and LS than EVT in patients with IM P1. Conversely, no differences in wound healing or LS were observed between groups in patients with IM P0. Bypass surgery should be considered a better revascularization strategy than EVT in patients with tissue loss and IM P1 disease.
Postoperative pain control is important in helping patients who underwent abdominal surgery to recover and to live a normal life. There is a method of administering painless injections to relieve postoperative pain. Currently, IV-PCA is mostly used. However, this method has a disadvantage in that the dosage of the opioid-based analgesic is increased, and thus side effects may be concerned. By administering analgesics through an epidural route approached through the thoracic vertebrae rather than intravenous injection, effective post-operative pain control and less side effects can be expected in lesser amounts. This study prospectively compared the pain control effects of IV-PCA and PCEA in patients undergoing resection of hepatobiliary tumors at the National Cancer Center, revealing that PCEA is more effective in alleviating pain after surgery. It has a purpose. In addition, the investigators will investigate and compare clinical outcomes (first fart, dietary progression, postoperative complications, etc.) of the two patient groups and investigate the side effects of PCEA and complications related to the procedure.
It is largely unknown how the tongue base and soft palate deform to alter the configuration of the oropharyngeal airway during respiration. This study is to address this important gap. After live sleep monitoring of five Yucatan and two Panepinto minipigs to verify obstructive sleep apnea (OSA), eight and four ultrasonic crystals were implanted into the tongue base and soft palate to circumscribe a cubic and square region, respectively. The 3D and 2D deformational changes of the circumscribed regions were measured simultaneously with electromyographic activity of the oropharyngeal muscles during spontaneous respiration under sedated sleep. The results indicated that both obese Yucatan and Panepinto minipigs presented spontaneous OSA, but not in three nonobese Yucatan minipigs. During inspiration, the tongue base showed elongation in both dorsal and ventral regions but thinning and thickening in the anterior and posterior regions, respectively. The widths showed opposite directions, widening in the dorsal but narrowing in the ventral regions. The soft palate expanded in both length and width. Compared to normal controls, obese/OSA ones showed similar directions of deformational changes, but the magnitude of change was two times larger in the tongue base and soft palate, and obese/OSA Panepinto minipigs presented 10 times larger changes in all dimensions of both the tongue base and the soft palate. The distance changes between the dorsal surface of tongue base and soft palate during inspiration increased in normal but decreased in obese OSA minipigs.
Participants will receive a single research MR imaging using HP 13C pyruvate, intravenously injected at a rate of 5 ml/second followed by a 20-ml saline flush at 5 ml/second. Safety monitoring, including vital signs and symptom monitoring will be performed for 30 minutes after dosing is completed, 1 to 3 days after dosing, and up to 30 days post scanning procedure. During the follow-up period, study personnel will obtain clinical data from the participants' medical records.