The annual failure of composite restoration represents 1 to 5 % with anterior teeth and 1 to3 % with posterior teeth . Many challenges appeared to be the causative factors of this failure such as the technique sensitivity of its placement, polymerization shrinkage, type and design of the cavity, location of the tooth, adhesive materials used last but not least operator and patient related factors. Some of these obstacles can be controllable and others cannot. According to the systematic review published in 2022, the most common reasons for composite failure are marginal deterioration which led consequently to secondary caries, marginal discoloration and post operative hypersensitivity. Restoration of the cervical carious lesions represents a great challenge to the restorative dentist due to the complicated clinical situation which include difficult isolation, variation in the tooth substrates and intraoral biomechanical challenges. Lots of modifications in the resin composite material and technique of application have been done and they are still ongoing to overcome the abovementioned inherited shortcomings.

The smear layer is considered as an unstable structure that affects the chemical and mechanical bonding between the restoration and tooth structure. There are different techniques to deal with the smear layer, either to remove, modify or dissolve it. Total removal of this layer with35-37% Phosphoric was the most used technique for preparing the tooth substrate to receive resin composite restoration. However, postoperative hypersensitivity was a repeated complaint from the patients. Selective enamel etching technique was introduced to solve this problem by only applying the phosphoric acid on the enamel margins and the multimode adhesive incorporating mild acidic monomer will achieve the dentin conditioning mission. Later, it was concluded that the clinical performance of multimode adhesives with etch, and rinse mode was better than with self-etch mode. Furthermore, there is available commercial product introduced to deal with the tooth substrate in a different way which is the multifunction nitric acid etch. It contains acid which enable the etching ability and cauterize the minor bleeding, isopropyl alcohol which acts as an antibacterial agent and cleans the surface before bonding and Hydroxyethyl methacrylate (HEMA) is a desensitizer which block the dentinal tubules to reduce the hypersensitivity.

Another concern, which can maximize the performance of the restorative system is the implementation of the bioactive property in the restorative system. The concept of bioactivity was achieved by introducing materials which interact with the surrounding tissues and produce a specific effect in the form of biological response or release of active substances. This release encourages remineralization and improves health, longevity and tissue regeneration. The idea of bioactivity was first introduced in dentistry by Larry Hench in 1960. Furthermore, the bioactive materials have many properties like inhibition of the bacterial growth by releasing calcium, sodium, silica and phosphate ion and an osteogenic property due to the use of calcium phosphate or tricalcium phosphate . Many trials were conducted to study the influence of using the bioactive materials in the restorative dentistry as the addition of fluoride, calcium phosphate particles and bioactive glass. The first used bioactive glass in dentistry was 45S5 glass in 1988. It is considered as a rich source of minerals which plays an important role in tooth remineralization. The remineralization is considered nowadays the most effective way to compensate the loss in tooth structure . Giomer is considered one of the most common categories of the bioactive materials. It relies on the incorporation of the surface pre reacted glass ionomer particles in its composition. Another category is termed as mineral enriched restorative system which incorporates bioactive glass in its composition . Such bio constructive materials work in conjugation with the healing ability of the human body to help in reinforcement of the tooth substrate. The bioactive glass is calcium sodium phosphosilicate based material which releases calcium and phosphate, increases the pH and optimizing the conditions for remineralization. Also, it contains hydrated silica which aids in the formation of hydroxyapatite like layers on the surface of restoration preventing the penetration of bacteria and secondary caries development. By adding the bioactive material, the restorative system will be able to survive for an extended time. Unfortunately, reviewing the literature revealed absence of any clinical trials that study the performance of multifunction nitric acid etch and the mineral enriched adhesive and flowable resin composite.