anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
The invention relates to means for applying coloured marking on a defective contact on the occlusion surfaces (18, 20) of a prosthetic false tooth and of a positive model (10) of an impression part prepared for the false tooth and/or the chewing surfaces of teeth. The marking means contains a powdered pigment, preferably red HgS, with a particle size of 1 to 20 νm insolubly suspended in a coating liquid which has a higher rate of evaporation than water at room temperature. When the liquid evaporates, the pigment forms a powdered residue which can be wiped off. To mark the defective contacts, the pigment powder is mixed with the coating liquid to form a suspension of low viscosity and then immediately applied uniformly with a paintbrush onto the occlusion surfaces (18, 20), the positive model (10) and/or the chewing surface of a tooth. After application, the application liquid is evaporated, leaving a layer of pigment powder which can be wiped off. The false tooth is then placed on the positive model (10) or on the antagonist to be marked and its chewing surface is pressed against the tooth. When the false tooth is pulled or lifted off, pigment particles on the defective contacts adhere to it.
PURPOSE: To incorporate improved polydextrose into food and to obtain polydextrose-contg. low calorie confectionery ensuring uniform dissolution in the mouth by aggregating polydextrose powder into granules having remarkably improved processability. CONSTITUTION: Polydextrose powder is brought into tight contact with a bonding soln. selected from among a sorbitol soln., an alginate soln. and a mixture of them for a sufficiently long time to aggregate and granulate the powder, compressed tablets are formed from the resultant granules and low calorie confectionery is produced. The bonding soln. may be sprayed on the polydextrose powder or a uniform mixture of the powder with an extending agent under conditions in aggregation in a fluidized bed. The particle size of the polydextrose is increased and the objective compressed tablets for confectionery having high flowability and remarkably improved compressibility is obtd.
Four tyrosine kinase inhibitors, alectinib, apatinib, lenvatinib and anlotinib, have been shown to be effective in the treatment of clinical tumors, but their cardiac risks have also raised concerns. In this study, zebrafish embryos at 6 h post fertilization (hpf) were exposed to the four drugs at concentrations of 0.05-0.2 mg/L until 72 hpf, and then the development of these embryos was quantified, including heart rate, body length, yolk sac area, pericardial area, distance between venous sinus and balloon arteriosus (SV-BA), separation of cardiac myocytes and endocardium, gene expression, vascular development and oxidative stress. At the same exposure concentrations, alectinib and apatinib had little effect on the cardiac development of zebrafish embryos, while lenvatinib and anlotinib could induce significant cardiotoxicity and developmental toxicity, including shortened of body length, delayed absorption of yolk sac, pericardial edema, prolonged SV-BA distance, separation of cardiomyocytes and endocardial cells, and downregulation of key genes for heart development. Heart rate decreased in all four drug treatment groups. In terms of vascular development, alectinib and apatinib did not inhibit the growth of embryonic intersegmental vessels (ISVs) and retinal vessels, while lenvatinib and anlotinib caused serious vascular toxicity, and the inhibition of anlotinib in vascular development was more obvious. Besides, the level of reactive oxygen species (ROS) in the lenvatinib and anlotinib treatment groups was significantly increased. Our results provide reference for comparing the cardiotoxicity of the four drugs.
The formulation for Hyoscyamine Sulfate Sustained Release Tablets is a non-eroding, non-gelling sustained release matrix. The drug releases from the tablet while the tablet remains intact. Therefore, it is possible that a tablet may appear in your stool.

This medication should be taken 30 minutes to one hour before meals. Tablets should be swallowed whole.

This medication should be used with caution during exercise or hot weather; overheating may result in heat stroke.

Hyoscyamine may cause drowsiness, dizziness or blurred vision; patients should observe caution before driving, using machinery or performing other tasks requiring mental alertness.
OBJECTIVES: I. Determine the efficacy of a 5-day continuous infusion of carboplatin and topotecan in patients with relapsed and refractory acute myelogenous leukemia (AML). II. Assess the toxic effects of this treatment in these patients.

OUTLINE: Patients receive continuous intravenous infusions of topotecan and carboplatin for 5 days. Treatment repeats every 3-4 weeks during induction (two courses) and every 6-10 weeks during consolidation. No more than four courses of treatment are given. Patients are followed every 6 months for 5 years.
Subjects in the bant Group will receive care as usual, as well as an iPhone loaded with the bant iPhone application and a bluetooth enabled glucometer. Participants will have their A1C levels measured every 3 months (for 1 year), and also complete questionnaires/interviews relating to their diabetes management and lifestyle.
Black Americans have a greater morbidity and mortality related to cardiovascular diseases compared to whites. The cause for this phenomenon is probably multifactorial and includes differences in pathogenesis, risk factor patterns, genetic background, behavioral variables, strategies for education and prevention, and socioeconomic factors. Recent evidence suggests that acceleration of some of the processes related to vascular biology may account for the greater prevalence of cardiovascular disease in blacks. A diminished vasodilator response of the microvasculature has been shown in African Americans and may therefore be responsible for their increased prevalence of hypertension. Endothelial dysfunction is a central mechanism in the development of atherosclerosis. It is therefore reasonable to postulate that endothelial dysfunction of large conductance arteries may also contribute to a greater susceptibility to atherosclerosis in blacks compared to whites, even in those individuals without the known risk factors for coronary heart disease. In the present study, we propose to investigate brachial artery dilation in response to endothelium-dependent and -independent stimuli in black and white individuals to determine whether racial differences in the vascular biology of large conductance vessels that might contribute to the greater cardiovascular morbidity and mortality previously reported in blacks.
Current reduced intensity conditioning regimens have been able to decrease TRM (treatment related mortality) but suffer from increased rates of disease relapse. Disease burden at transplantation, as measured by percent myeloblasts, predicts relapse. Current regimens employ fludarabine and busulfan with various adjutants, but these agents are not part of the usual armamentarium used versus leukemia and have questionable anti-leukemic activity. By substituting clofarabine and cytarabine, a combination with proven anti-leukemic activity in the relapsed and refractory setting as well as activity versus MDS, as the back bone of the regimen we hope overcome residual disease and improve post-transplant relapse rates. Furthermore the principal toxicity of this regimen is myelosuppression, which should be abrogated by the infusion of stem cells. Thymoglobulin is included due to its minimal contribution to toxicity but significant benefits in engraftment, and controlling acute and chronic GVHD, which are major contributors to TRM and disease specific activity in MDS.
A method of analyzing physiological data streams. According to the method, physiological data is received into a computerized machine. The physiological data comprises numerical data and medical symptoms of a patient. Features are extracted from the physiological data based on development of the physiological data over a period of time. The features are converted into a textual representation using natural language generation. Input terms for an information retrieval system operating on the computerized machine are automatically generated based on the features. The input terms are input to the information retrieval system. A corpus of data is automatically searched to retrieve results to the input terms using the information retrieval system.
Examples described herein generally relate to referring a patient to a provider for a drug use disorder. A computer system accesses a plurality of provider data records. The system determines a geographical location of the patient. The system searches, within a geographical distance of the geographical location for a provider that satisfies patient requirements based on a patient data record. The system determines one or more certified providers that are certified to treat a condition of the patient. The system determines that one or more of the certified providers has an available opening for the patient. The system determines an outcome rating for the patient and each certified provider based on the patient data record. The system matches the patient to a certified provider with a best outcome rating that accepts payment from a payer for the patient. The system refers the patient to the matched provider.
PROBLEM TO BE SOLVED: To provide a silicone rubber powder with reduced ill smell which would occur in the course of time, even in the presence of a polyether compd. and water, an effective method for preparing the rubber powder, and a cosmetic with reduced ill smell which would occur in the course of time, although the cosmetic comprises the rubber powder, a polyether compd. and water. SOLUTION: This silicone rubber powder is prepd. by impregnating, in the presence of a platinum type catalyst, a compd. which lowers the catalytic action of the platinum type catalyst in a silicone rubber powder crosslinked by the hydrosilylation. The preparation of the silicone rubber powder is conducted by impregnating, in the presence of a platinum type catalyst, a compd. which lowers the catalytic action of the platinum type catalyst in a silicone rubber powder crosslinked by the hydrosilylation. This cosmetic comprises at least the silicone rubber powder, a polyether compd., and water.
No data are available on overdose of DELSTRIGO in patients and there is no known specific treatment for overdose with DELSTRIGO. If overdose occurs, the patient should be monitored and standard supportive treatment applied as required.

Doravirine: There is no known specific treatment for overdose with doravirine.

Lamivudine: Because a negligible amount of lamivudine was removed via (4-hour) hemodialysis, continuous ambulatory peritoneal dialysis, and automated peritoneal dialysis, it is not known if continuous hemodialysis would provide clinical benefit in a lamivudine overdose event.

TDF: TDF is efficiently removed by hemodialysis with an extraction coefficient of approximately 54%. Following a single 300 mg dose of TDF, a 4-hour hemodialysis session removed approximately 10% of the administered tenofovir dose.
Multipurpose skin preparations in the form of oil-in-water emulsions are disclosed. The skin preparations are prepared by combining an oil phase and an aqueous phase. The oil phase comprises a siloxane polymer, a cyclic silicone, an anti-oxidant, and an emollient. In a second version of the present invention, the oil phase includes a copolymer comprising PPG-12/SMDI. The aqueous phase comprises at least a humectant, a rheology modifier, a thickener, and water. The inventive preparations are useful in topical application to the skin, are highly water resistant, remain on the skin after multiple washings, form a protective barrier on the skin, and effectively deliver and maintain moisturizing and therapeutic agents on the skin. It is believed that the skin preparations of the present invention also effectively deliver and maintain moisturizing and select therapeutic agents, biological agents, pharmaceutical agents, and the like, which are useful for the treatment of pathologies of the skin.
Patients in biomarker guided positive treatment arm were given Montelukast Sodium Tablets (p.o., 10mg, q.d.) . Patients in biomarker guided negative treatment arm were given placebo tablets (main excipient lactose monohydrate).
Titanium implants the surfaces of which were roughened with SLA (sandblasted and acid-etched titanium surface) (Straumann®, Basel, Sweden). Immunological parameters (PICF, Perio-paper®) , microbiological parameters of peri-implantitis (subgingival plaque, Hu-Friedy®), demographic and clinical periodontal measurements (Williams probe, PCPNU-15 Hu-Friedy®) were compared between groups.
PURPOSE: A composition containing an extract of a green tea by-product for preventing and treating animal diseases caused by influenza virus is provided to ensure a excellent antiviral effect in vivo and in vitro and to be used in a veterinary composition and feed additives. CONSTITUTION: A veterinary composition for preventing and treating diseases caused by virus in animals except for human contains an extract of green tea by-products as an active ingredient. The diseases are caused by infection of influenza virus family. A feed additive, a feed composition, and a pharmaceutical composition for preventing and treating the diseases contain the extract as an active ingredient. The extract is prepared from catechin-removed green tea by-products. [Reference numerals] (AA) Sample; (BB) Green tea extract; (CC) Green tea by-product extract
Approval from Ethical Committee of Faculty of Medicine Universitas Indonesia was acquired prior conducting the study. 34 subjects were enrolled by using consecutive sampling method. Sample size was calculated by using numeric analytic comparative paired formula with repeated measurement. Inclusion criteria were patients with ASA score 1 and 2, aged between 18-60 years old, no anatomical abnormality in neck. Exclusion criteria were patients who were either obese, has history of previous central venous catheter cannulation, and limitation on contralateral head movement. Drop out criteria was abnormalities of anatomical IJV and CA. Basic demographic data, such as sex, age, body weight and height, body mass index were recorded. Patients were positioned in Trendelenburg (15°) position. Identification triangle of Sedillot at cricoid level in right neck with palpation at angle 0°. USG probe was placed upright at the top of triangle of Sedillot at cricoid level. Identification of IJV and CA was shown in transversal view then the IJV to CA distance and overlap ratio was calculated. Contralateral head rotation was done with protractor at angle 30°, 45°, and 60°. The distance and overlap ratio of IJV and CA was calculated in each angle.
<P>PROBLEM TO BE SOLVED: To provide a method for evaluating the presence/absence or the degree of an edema by a simple and highly precise method, and to provide a method for evaluating the anti-edema action of a substance to be tested by a simple and highly precise method.  <P>SOLUTION: This evaluation method for edema measures the pinna sizes of mammals induced by a water intake or a water dosage. Also, the evaluation method for the anti-edema action of the substance to be tested includes the following four processes. In the process (i), an edema is induced to a mammal by dosing water. In the process (ii), the substance to be tested is dosed to the mammal before or after dosing water. In the process (iii), before dosing water, and after dosing water, and also, after dosing the substance to be tested, the size or the elasticity of the pinna of the mammal is measured. In the process (iv), the anti-edema action of the substance to be tested is evaluated from a difference between the measured value for the size or the elasticity of the pinna before dosing water, and the measured value of the size or the elasticity of the pinna after dosing water, and also after dosing the substance to be tested.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patients in the experimental group will have a nipple-delay intervention in addition to usual care. The nipple delay procedure will be performed by the plastic surgeon in the minor clinic procedure room under local anaesthetic 7 - 21 days prior definitive NSM with IBR. The skin flap will be elevated in the plane of the prophylactic mastectomy beneath the NAC. A nipple core biopsy and a 1cm thick biopsy of immediately subareolar ductal tissue will be submitted for permanent section pathology. This approach is consistent with the previous case series of nipple delay for NSM and approved by the multi-disciplinary breast cancer team at our institutions. Patients that have a positive nipple core or sub-areolar biopsy will have the NAC removed at time of definitive mastectomy.
Patients receive pembrolizumab IV over 30 minutes on day 1, etoposide IV over 60 minutes on days 1-3 of courses 1-2, carboplatin IV over 60 minutes on day 2 of courses 1-2, and ifosfamide IV over 24 hours on day 2 of courses 1-2. Pembrolizumab in combination with ICE chemotherapy repeats every 21 days for 2 courses, patients will then receive pembrolizumab as monotherapy on course 3.
One dose of preoperative intravenous (iv) antibiotic (e.g., cefazolin 1gm, or cefuroxime 1.5gm, or clindamycin 300mg will be administered within 60 minutes of start of surgery. Repeat intraoperative dosing of antibiotics is permitted if length of surgery exceeds recommended dosing interval. IV antibiotic dosing schedules: Cefazolin 1 gm iv Q6 hr -or- Cefuroxime 1.5gm iv Q8 hr -or- Clindamycin 300 mg iv Q12 hr. Postoperative antibiotics: Study participants will receive one dose only of postoperative intravenous antibiotic (e.g., cefazolin 1gm, or cefuroxime 1.5gm, or clindamycin 300mg \[cephalosporin allergic patients\]) according to the recommended dosing schedule described above. This dose of antibiotics is in addition to the preoperative dose. Placebo PO BID (twice daily) will commence on the morning of postoperative day 1 and continue for 7 days.
FIELD: medicine, sexology. SUBSTANCE: agent of intimate designation for males containing an antiviral preparation and a base has additionally a stabilizing agent of biological, physico-chemical properties and/or of resistance to bacterial contamination and alpha-, beta- or gamma-recombinant interferon as an antiviral preparation. Agent has additionally an antioxidant, lipophilic, hydrophilic or lipophilic-hydrophilic base and beta-carotene, dimethylsulfoxide and ridostine additionally also. Agent is made as an ointment, gel, cream or emulsion and designated for condom lubrication. Invention can be used for treatment and prophylaxis of diseases contaginated by sexual way. EFFECT: enhanced effectiveness of antiviral and antibacterial agent. 11 cl
Patient's randomized to SLT would be treated with the following settings: 400 micron spot size, 0.3 second duration, and 1.00 milliWatt (mW) power. They would be treated with confluent laser spots across the entire 360 degrees of the trabecular meshwork. Each patient would receive pre-treatment with a drop on iopidine or brimonidine to prevent post-operative IOP spikes as per standard pre-laser trabeculoplasty protocol.
The active comparator condition consists of exposure to light to reduce cancer-related fatigue. This group will self-administer 30 minutes of light from commercially available light glasses each morning for 4 weeks.
<P>PROBLEM TO BE SOLVED: To provide a new human receptor protein 4-1BB.  <P>SOLUTION: The cDNA has a specific nucleotide sequence encoding the human receptor protein 4-1BB. The human receptor protein 4-1BB has a specified amino acid sequence. The fused protein comprises an extracellular part having the human receptor protein 4-1BB and an alkali phosphatase. The method for treating a T-cell having the receptor protein 4-1BB with a monoclonal antibody recognizing the human receptor protein 4-1BB is also provided to promote the activation of the T-cell.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
An apparatus is provided for continuous and regular liberation of active constituents into domestic water supplies. The apparatus comprises a receptacle having a body portion which is impermeable to water and to the active constituent. The receptacle is provided with an aperture closed by a membrane which is permeable to water and to the active constituent. An operculum surrounds the membrane to secure the membrane to the receptacle. The active constituent is provided into the receptacle and is released through the membrane in a controlled manner over an extended period of time. Preferably, the membrane has a mean pore diameter greater than 0.05 microns.
OBJECTIVE: To evaluate the initial efficacy of comprehensive treatment of external treatment of traditional Chinese medicine in the therapy of acute mastitis during lactation and its influence on sufferers' symptoms.
METHODS: From January 2021 to January 2023, a retrospective analysis was performed on 100 sufferers with acute mastitis during lactation who were received in our hospital as the study objects. Divided them into a control group (n = 50) and an observation group (n = 50). Among them, the control one was received in 50% magnesium sulfate for moist heat compress, and the observation one was treated with comprehensive external therapy of traditional Chinese medicine. After different treatment measures were carried out in the 2 groups, the total effective ratio of clinical therapy, excellent and good rates of lactation, quality of life measurements, pain scores before and after treatment, and TCM symptom points at pre-therapy and post-therapy, negative emotion scores at pre-therapy and post-therapy related to patients were analyzed.
RESULTS: (1) In the data comparison of the total effective ratio of clinical therapy between the 2 groups of sufferers after therapy, the data in the observation one were greater than the control one, and the distinction was obvious, with P < .05. (2) In the data comparison of the excellent and good lactation rate between the 2 groups of sufferers at post-therapy, the data in observation one were greater than the control one, and the distinction was obvious, with P < .05. (3) In the data comparison of quality of life measurements between the 2 groups of sufferers at post-therapy, the data in the observation one were greater than the control one, and the distinction was obvious, with P < .05. (4) Before treatment, it had no obvious distinction in the pain scores between the 2 groups, with P > .05; in the data comparison of the pain points between the 2 groups after therapy, the data in observation one were less than the control one, and the distinction was obvious, with P < .05. (5) Before therapy, it had no obvious distinction in TCM symptom points between the 2 groups, with P > .05; in the data comparison of TCM symptom points between the 2 groups after therapy, the data in the observation one were less than the control one, and the distinction was obvious, with P < .05. (6) Before therapy, it had no obvious distinction in negative emotion points between the 2 groups, with P > .05; in the data comparison of negative emotion scores between the 2 groups of sufferers at post-therapy, the data in the observation one were less than those in the control one, and the distinction was obvious, with P < .05.
CONCLUSION: The comprehensive therapy of TCM external treatment for acute mastitis during lactation has a significant therapeutic effect, which is conducive to improving the clinical symptoms of sufferers as soon as possible and at the same time, greatly improving the life quality of sufferers and improving their negative emotions, which can relieve the pain of sufferers and promote the recovery of the sufferers.