anthonyyazdaniml/gliner-biomed-curated-corpus huggingface dataset:
A system and method for conservation of battery power in a portable medical device is provided. In one example, a processor arrangement includes a dual core processor having an ARM core and a DSP core. The portable medical device includes a monitor having the dual core processor, in communication with a belt node processor. The DSP core receives physiological data from the physiological sensor and sends the physiological data to the ARM core. The ARM core analyzes the physiological data to determine if a treatment sequence is necessary. The DSP core receives physiological data from the at least one physiological sensor and sends the physiological data to the ARM core, and also analyzes the physiological data to determine proper timing of the treatment sequence by the at least one therapy delivery device to synchronize at least one pulse of the treatment sequence with the physiological data.
The present invention relates to a Chinese herbal medicine preparation which comprises a medicament prepared from main medicine digestive juice in capsule of pitcher plant and pharmaceutically-acceptable adjunctive medicine. The present invention also relates to a preparation method of the preparation and an application thereof. Because digestive juice in capsule of pitcher plant is adopted as main medicine, the present invention substantially utilizes the characteristics of digestive juice so that taken digestive juice which is led in the blood vessel can effectively digest and dissolve embolus, harden plaque and inflammatory factors in the blood vessel, decompose compound macromolecules of fat, cholesterin, saccharide, etc. in blood components, thereby effectively promoting the circulation of blood and dredging microcirculation. Simultaneously, because pitcher plant and pubescent holly root are adopted as minister medicine for a fit, the medicine of the present invention reduces the toxic and side effect to a minimum degree, ensures the edible safety, and further, enhances the treatment effect. The preparation of the present invention matched with western medicine for micro vascular dilatation can be widely applied to treatment and prevention of disease of hypertension, cardiovascular infarction, cerebrovascular infarction, renovascular infarction, diabetes, coronary heart disease, apoplexy, etc.
On the first test day we utilized 50 g of glucose dissolved in 200 ml water. The second day was washout day. On the third day we used 922 g of Majia pomelos which contained 50 g carbohydrate.This group of volunteers enrolled for the case control period.
LL37 administered intratumorally in cutaneous or subcutaneous tumors at least 1 cm in diameter. Patients will receive weekly intratumoral injections of LL37 for up to 8 weeks. The injections will be given every 7 days (+/- 48 hours). Starting dose 250 µg/tumor.
The invention discloses a fusion protein with anti-bacterial function, its construction method and application. The fusion protein is composed of a modified mouse Reg3 alpha anti-bacterial protein and six histidine and is a peptide containing an amino acid sequence as shown in SEQ ID NO.1. The construction method of the fusion protein is to connect a Reg3 alpha with an expression plasmid pwPICZalpha to construct a recombinant expression plasmid pwPICZalpha-Reg3 alpha. After linearization, the plasmid is integrated into the genome of pichia pastoris. Positive clone is selected and expression of the protein is induced. Then the fusion protein is obtained by ProteinPureNi-NTA resin and strong cation exchange resin purification. The fusion protein constructed by the invention has ability of anti-staphylococcus and can be applied in the production of antibacterial protein for animal feeding.
Experimental group was randomly assigned among the volunteers who met the inclusion criteria: men between the ages of 18 and 60 who had sperm motility of less than 32%. Fermented ginseng (GINST) was supplied.
The A\&RT program will be a four-times-per week program. Twice a week will be aerobic training consisting of outdoor walks with certified fitness instructors. The outdoor walking program will start participants out working at 45% of their heart rate reserve, and work up to 70% of the heart rate reserve. The other two days a week will be resistance training in which a pressurized air system and free weights will be used to provide the training stimulus. Other key strength exercises (with free weights) will include mini-squats, mini-lunges, and lunge walks. The intensity of the training stimulus will initially be at 50% to 60% of 1 repetition maximum (RM) as determined at week two, and progress to 75% to 85% of 1-RM at a work level of 6 to 8 repetitions (2 sets) by week four. The training stimulus will be increased using the 7 RM method, when 2 sets of 6-8 repetitions are completed with proper form.
Two subjects will be enrolled in a single dose group which is recommended as the initial dose. 8 out of 10 healthy subjects will be randomized to receive a single dose of SYHX 1901 tablets in fasted state.
The objective of this study was to explore the potential causalities of fat mass, nonfat mass and height (henceforth, 'anthropometric measures') with sepsis risk and mortality. We conducted the Mendelian randomization (MR) investigation using genome-wide association study (GWAS) summary statistics of anthropometric measures, sepsis, and sepsis mortality. The GWAS summary data from the UK Biobank was used. Firstly, MR analysis was performed to estimate the causal effect of anthropometric measures on the risk of sepsis. The inverse-variance weighted (IVW) method was utilized as the primary analytical approach, together with weighted median-based method. Cochrane's Q test and MR-Egger intercept test were performed to assess heterogeneity and pleiotropy, respectively. Finally, we performed a series of sensitivity analyses to enhance the precision and veracity of our findings. The IVW method showed that genetically predicted weight-related measures were suggestively linked to an increased risk of sepsis. However, height displayed no causal association with sepsis risk and mortality. Furthermore, weight-related measures also displayed significant MR association with the sepsis mortality, except body nonfat mass and right leg nonfat mass. However, MVMR analysis indicated the observed effects for weight-related measures in the univariable MR analyses are more likely a bias caused by the interrelationship between anthropometric measures. According to the MR-Egger intercept assessment, our MR examination was not influenced by horizontal pleiotropy (all p>0.05). Moreover, the reliability of the estimated causal association was confirmed by the sensitivity analyses. In conclusion, these findings provided vital new knowledge on the role of anthropometric-related measures in the sepsis etiology.
A method comprising receiving medical imaging data associated with a magnetic resonance imaging (MRI) scan, determining pulse sequence characteristics for the imaging data using a machine learning (ML) model, classifying the characteristics, and updating a database containing the imaging data to include the classified characteristics. Feature extraction may be applied to the imaging data prior to determining the characteristics. The imaging data and characteristics may be displayed to the user via an interface (GUI). A hanging protocol may be determined based on the characteristics and the imaging data displayed according to the hanging protocol. The ML model may be a convolutional neural network (CNN). The characteristics may include one of: whether fat suppression is present, an echo type of the MRI scan, an indication of whether fluid is bright, or whether a contrast is present. A DICOM tag may be generated for the imaging data based on the classification.
The B-SWELL arm consists of 8-weekly sessions. Sessions last 90 minutes and focus on stress reduction, heart disease, and healthy lifestyle changes. The American Heart Association's Life's Essential 8 metrics are leveraged and culturally tailored in the B-SWELL materials. Participants will also receive personalized health coaching.
Ibuprofen for Post operative pain. Take 400 mg takena week after. Incidence of flare ups after a single vsmultiple visits root canal treatments.
Although abdominal aortic aneurysms (AAA) are more common in men, women are at greater risk for AAA growth/rupture. Vascular deformation mapping (VDM) utilizes deformable image registration to qualify and quantify 3D-AAA growth using computed tomography angiograms (CTA). In this study we leveraged VDM to investigate sex differences in AAA growth patterns. Patients with infra-renal AAA and ≥ 2 CTA were identified. Males and females were matched for age, hypertension, and smoking history. Patient characteristics, maximum diameter (Dmax), and AAA volume were obtained. CTA images were segmented, and VDM was conducted to quantify 3D AAA growth rate per year (GR, cm/year). Statistical shape modeling was utilized to compute mean aneurysm shapes and 3D GR. Average GR was evaluated at specific regions of the aortic surface for males and females. Seventeen males and 17 females were matched. At the individual level, there were no sex differences in changes in Dmax or AAA volume. However, females had larger GR across the anterior and right lateral AAA (1.33 vs 0.89 and 1.56 vs 0.74 cm/year, respectively), despite no difference in posterior or left lateral AAA GR. Despite comparable changes in Dmax, AAA volume, and GR magnitude, women demonstrated a more eccentric, anterior-predominant, AAA growth pattern.
Methods and apparatuses for collecting and quantifying patient-reported data from a neuromodulator. The patient-reported data typically includes a pain score that quantifies the level of pain experienced by the patient at a particular time. The apparatus can include a user interface that allows the patient to enter such information in real time. The methods and apparatuses can include a correlation process, whereby each patient-reported entry is correlated with a corresponding neuromodulation treatment. This correlation can be used to identify treatment parameters and dosages that are most effective, and to further identify when certain dosages are most effective. This information can further be used as feedback to generate optimized treatments for a specific patient and iteratively improve the treatments. In some cases, the correlation process identifies under reported or over reported data, which can be filtered out to provide more accurate optimized treatments.
A total of 30 subjects will be randomized to this experimental arm. If randomized to this arm, subjects will receive dry needling, patient education, and a home exercise program.
BACKGROUND: Mucormycosis is a fungal infection caused by the Mucorales order of fungi. This fungus is commonly found in soil and can cause disease in immunocompromised patients. On the other hand, Bell's palsy is an idiopathic condition that results in the sudden onset of unilateral facial muscle weakness, affecting the facial nerve.
CASE PRESENTATION: A 51-year-old Persian housewife with a history of poorly controlled diabetes mellitus presented with a splitting headache that had been ongoing for 1 week and an inability to close her left eye or make facial expressions on the left side of her face. The patient's vital signs were normal, but physical examination revealed a yellow-grey scar on the left side of her hard palate and Bell's palsy on the left side. A neurological examination showed that she could move both eyes but could not close her left eye, move up her left eyebrow, or smile. Further investigations were performed, including laboratory tests, radiologic imaging, and functional endoscopic sinus surgery. The patient underwent three rounds of debridement for bony erosion in the medial and posterior walls of the left maxillary sinus and the hard palate. Pathological examination confirmed mucormycosis infection in the hard palate and mucosa.
CONCLUSION: Fungal infection must be considered a potential diagnosis for immunocompromised adults who exhibit symptoms of Bell's palsy.
PCT No. PCT/US87/00191 Sec. 371 Date Jul. 23, 1987 Sec. 102(e) Date Jul. 23, 1987 PCT Filed Jan. 29, 1987 PCT Pub. No. WO87/04594 PCT Pub. Date Aug. 13, 1987.This invention provides compositions comprising a compound having the structural formula  <IMAGE>  wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-17 and R is -CH3,  <IMAGE>  wherein R'' is H or halogen. The invention also provides compositions comprising a physiologically-active agent and the hereinabove recited 1-substituted azacycloalkane compound in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal. Other compositions of 1-substituted azacycloalkanes and their uses relate to an improved method of dyeing fibers, improved delivery of plant nutrients, improved plant pest control, improved delivery of plant growth regulations, improved acid-catalyzed conversion of a reactant into a reaction product and an improved insect repellant.
The invention provides tissue-specific and target RNA-specific ribozymes. These ribozymes can be used to destroy target-specific neoplasms and to treat viral infections, among other uses. The ribozymes of the present invention comprise a 5' autocatalytically cleaving ribozyme sequence, a catalytic ribozyme comprising a target RNA-specific binding site and a 3' autocatalytically cleaving ribozyme. The invention also provides nucleic acids which encode the ribozymes of the invention. These nucleic acids can be used to express the ribozymes of the invention at the selected site. Methods of treating disease by administering the ribozymes are provided.
Aging is often associated with chronic inflammation and declining health. Both veterinarians and owners of aging dogs and cats are interested in nutritional solutions and strategies to prevent signs of age-related disease, increase longevity, and improve quality of life. Physiological decreases in muscle mass, decreased immunity, and a decrease in sense acuity are some of the changes often seen in otherwise healthy senior pets; however, there may also be an increase in risk for pathologies such as renal, cardiovascular, musculoskeletal, and neoplastic diseases. Aging may also lead to cognitive decline and even cognitive dysfunction. Some nutritional strategies that may be helpful with the prevention and treatment of age-related diseases include supplementation with ω3 polyunsaturated fatty acids and antioxidant nutrients that can help modulate inflammation and benefit osteoarthritis, renal disease, cancer, and more. Supplementation with medium-chain triglycerides shows promise in the treatment of canine cognitive dysfunction as these may be metabolized to ketone bodies that are utilized as an alternative energy source for the central nervous system. Additionally, a high intake of dietary phosphorus in soluble and bioavailable forms can lead to renal disease, which is of greater concern in senior pets. There are no published guidelines for nutritional requirements specific to senior pets and as a result, products marketed for senior dogs and cats are highly variable.
A virtual agent converses with a patient or other person to assess one or more psychological or other medical conditions of the other person. The virtual agent uses both semantic and affect content from the person to branch the conversation, and to assess a psychological or other condition of the person. The virtual agent can have artificial intelligence functionalities or can utilize a separate artificial intelligence functionality. A communication agent can be utilized to monitor a telecommunication session with the person, and if appropriate, modify relative bandwidth utilization between the audio and image inputs. The virtual agent/artificial intelligence agent can simultaneously assist multiple virtual agents, who are each conversing with a responding person assessing their psychological or other medical condition(s), in parallel. The contemplated virtual agents can be especially useful in assessing disorder severity in multiple neurological and mental disorders.
PURPOSE:To provide as rinse with transparency by using both a condensed castor oil fatty acid amidopropylbetaine and a polyhydric alcohol. CONSTITUTION:(A) A nonionic surfactant such as polyoxyethylene sorbitan monostearate or glycerol monostearate is blended with (B) a condensed castor oil fatty acid amidopropylbetaine and (C) a polyhydric alcohol such as glycerol, ethylene glycol or propylene glycol in the ratio of 0.1-15 pts.wt. component A, 0.1-20 pts.wt. component B and 0.1-30 pts.wt. component C by weight to give the objective rinse. Optionally the rinse is further mixed with S 15 pts.wt. cationic surfactant. The component B is a new substance and is obtained by amidating a condensate of (hydrogenated) castor oil fatty acid with N,N- dimethylaminopropylamine and quaternizing the tertiary nitrogen of the obtained amide with monochloroacetic acid. A compound wherein the condensate is a condensate of recinolic acid and its degree of condensation is (n) is shown by the formula.
Human ascariasis is a soil-transmitted helminthiasis and remains a neglected tropical disease. Ascaris suum has the potential to cause cross-infections between humans and pigs. In this study, we present a rare case of a patient with asymptomatic infection by Ascaris suum. A 66-year-old male underwent colonoscopy, and a white linear worm body was found in the hepatic curvature. The worm was collected by aspiration and submitted to the laboratory for parasite identification. The patient had no symptoms related to parasitic infection. The worm was highly suspected to be of the genus Ascaris. Because of the difficulty of morphological classification, genetic analysis was performed. From PCR-restriction fragment length polymorphism results and sequence analysis of the internal transcribed spacer-1 region, it was determined to be A. suum. The experience with rapid differentiation of A. suum by performing genetic analysis will be useful for future examinations of parasitic infections.
In the control group, the position will follow the routine procedure of the Hospital Barão de Lucena, consisting of the use of restraint nests "U", made with rolled sheet placed on the mattress of the incubator and covered by another sheet. The control group incubators will also be inclined at 30 ° as routine service. During the 8 position, switching the supine will also be held, side left and side right after the baby handling to cleaning procedures, diet and medical evaluation.
Transcranial magnetic stimulation (TMS) is currently approved by the FDA for the treatment of depression, obsessive compulsive disorder, and smoking cessation. Despite evidence that TMS improves symptoms by modulating brain connectivity, the few published studies that have measured brain connectivity before and after neuromodulatory TMS have been population-, dose-, and pattern-specific, with connectivity effects that are limited in scope to a handful a priori regions of interest. Accordingly, there is a critical need for generalized, comprehensive model that explains how functional brain connectivity changes at the whole-brain level following neuromodulatory TMS. Therefore, the objectives of this grant are to 1) develop a model using whole-brain estimates of the TMS-induced electric (e)-field to predict changes in resting state functional connectivity following neuromodulatory TMS, and 2) validate this model in a large cohort of healthy volunteers receiving multiple doses of either intermittent or continuous theta burst stimulation (iTBS and cTBS, respectively). Our central hypothesis is that changes in functional connectivity will vary systematically with the current density at the cortex, operationally defined using e-field modelling. Investigators have pilot data suggesting that the variability in pre-post rsFC changes following TMS can be predicted using estimates of the current density at the cortex with a medium to large effect size. Our approach will be to measure rsFC in healthy volunteers before and after each of 3 doses (5 sessions/dose; 600 pulses/session) of iTBS or cTBS. Stimulation will be delivered to the left dlPFC, and targeting will be individualized based on fMRI data collected during the Sternberg working memory paradigm. Our primary outcome measure will be the percent of variability in pre-post rsFC accounted for by our model. Our rationale for this approach is that by collecting resting state data pre and post these doses of iTBS and cTBS, investigators will be able to quantify the effect of pattern (i.e. cTBS vs. iTBS) and dose (i.e. number of pulses) on functional connectivity changes. This work is innovative because it uses a novel application of e-field modelling to predict changes in rsFC data following TMS administration. PUBLIC HEALTH RELEVANCE: This work is relevant to public health because it will provide direct evidence that functional connectivity changes following neuromodulatory TMS vary as a function of the current density at the cortex. The empirical support for this model gained from this current work will set the stage for the use of this model for individualized targeting in subsequent clinical trials. Importantly, because of the domain-general nature of this approach its application is not limited to any specific disorder. Likewise, because our approach is not tied to any specific functional connectivity feature, it can be applied to regions outside those currently under investigation, which could facilitate target discovery in understudied disorders.
The invention discloses a formula of a traditional Chinese medicine for treating hypotension. The traditional Chinese medicine comprises licorice root, cassia twig and cassia bark. The unit dosage of the traditional Chinese medicine comprises 20g of licorice root, 40g of cassia twig and 40g of cassia bark. A preparation method of the traditional Chinese medicine comprises weighing the above traditional Chinese medicines and mixing the traditional Chinese medicines and boiled water at a temperature of 80 DEG C. The soup is used as a tea and is taken for one week. The traditional Chinese medicine solves the problem that the conventional treatment drug has a high recurrence rate and large side effect, has a long use period, causes addiction, has a high recurrence rate after drug discontinuance and cannot thoroughly cure diseases. The traditional Chinese medicine is suitable for treatment on hypotension.