anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
Beverages are provided and administered for producing LIS samples containing cells exfoliated from throughout the gut in sufficient numbers and free of interfering substances such as formed fecal particles for chemical assays and biologic assays for nucleic acid sequence information, and medical diagnosis. A kit is also provided for use by patients without assistance to produce a LIS sample suitable for analysis. A collection kit employs a sequence of the beverages and other ingested substances to produce preserved cells for medical diagnosis, allowing cytologic analysis of the LIS for diagnosis of foregut and hindgut disease. A preliminary cathartic lavage is used to cleanse a patient&#39;s digestive tract; at least one stool induced by the preliminary cathartic lavage is collected; and a final cathartic lavage is used to exfoliate and preserve cells from a patient&#39;s digestive tract. Time release capsules containing a cathartic medicament can also be used after completing preliminary lavage administration. The kit also provides apparatus for collection, sealing, and packing of the collected LIS specimen for analysis.
A 6-deoxytetracycline of formula:  &lt;FORM:0871423/IV (b)/1&gt; is produced by catalytically reducing with hydrogen a tetracycline of formula:  &lt;FORM:0871423/IV (b)/2&gt; wherein R1 is hydrogen or methyl, R2 is hydrogen or hydroxy, R3 and R4 are hydrogen or dimethylamino with the proviso that both may not be hydrogen or dimethylamino and R5 is chlorine or bromine, R2 only being hydroxy when R1 is methyl, or an acid addition salt thereof, the reaction being carried out in a polar solvent solution in the presence of a noble metal catalyst and a substance capable of forming a chelate ring with a peri-dioxygenated hydronaphthalene, until approximately one molecule of hydrogen has been absorbed per mol of tetracycline.  A temperature of 0-100 DEG C. and pressure of 1/2 to 100 atmospheres is used.  The catalyst may be palladium or platinum especially suspended on a carrier.  The substances capable of forming a chelate ring may be boric acid, boron trihalides e.g. boron trifluoride, aluminium salts such as the chloride and magnesium salts such as the acetate.  The preferred reaction solvent is a mixture of water and dimethylformamide.  The 6-deoxytetracycline may be converted to (a) the acid salt by treatment with an acid at a pH below 4.0 e.g. sulphate, phosphate, oxalate, citrate, gluconate and trichloroacetate (b) the alkali metal and alkaline earth metal salt by treatment with the appropriate base to a pH above 6,0 (c) a metal complex of a metal salt such as aluminium gluconate and (d) the 4-epimer by maintaining a pH 3.0 to 5.0 and allowing to stand.  Specification 815,524 is referred to.
A non-magnetic cobalt based &#34;noble&#34; metal dental alloy is provided. The dental alloy comprises a formulation of a cobalt based high palladium content alloy that is consistent with the American Dental Association (ADA) guidelines for &#34;noble&#34; alloys required for use in dental products (i.e. alloys having at least 25% gold or palladium). The cobalt based palladium containing alloys may be rendered non-magnetic through the additions of higher concentrations of other alloying elements. The cobalt based alloy generally contains at least 25 wt.% palladium, or may contain at least 25 wt. % gold plus platinum group elements with the majority of the 25% addition consisting of palladium. The alloy also contains chromium and may include 0 to 20 wt. % of molybdenum and/or tungsten, tantalum, niobium, vanadium, and rhenium.
Pure bile acids are isolated from the bile of warm-or cold-blooded animals by treating the bile raw material, or a product obtained therefrom by mild alkaline hydrolysis or esterification, in a solvent system of is not2 phases in one phase of which the bile acids or their derivs. are soluble and the pigments and other impurities (or their derivs.) are insoluble and in the other phase(s) of which the bile acids or their derivs. are insoluble and the pigments and other impurities (or their derivs.) are soluble; separating the phases from each other. isolating the bile acids or their derivs. from the phase contg. them; and opt. subjecting to further purification steps. Process is simple and economical giving bile acids of &gt;99% purity. Suitable bile starting material is that obtained from birds (giving 3alpha, 7alpha-dihydroxy-5beta-cholanic acid as main product) or fishes.
The invention discloses a new traditional Chinese medicine composition for treating advanced malignant liver tumor symptoms and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared from the following medicine components: angelica, tuckahoe, hemlock parsley, cassia twig, dried ginger, Bupleurum, kudzu root, Baikal skullcap root, coptis, flavescent sophora root, honeysuckle, Taraxacum, pangolin, leech, natural indigo, subprostrate sophora, moutan bark, red-rooted salvia root, red paeonia, white peony root, white atractylodes rhizome, gromwell, cornu antelopis powder, rhubarb, magnolia bark, three-nerved spicebush root, notoginseng, madder, draconis sanguis, rhizoma corydalis, raw Astragalus root, codonopsis pilosula, peach seed, safflower, turmeric, Endothelium Corneum Gigeriae Galli, Fructus Aurantii Immaturus, Polyporus umbellatus, rhizoma alismatis, Plantain seed, climbing fern spore, giant knotweed, Evodia rutaecarpa, nut grass, galangal and allium macrostemon. The traditional Chinese medicine composition can be prepared into any commonly-used oral preparation by using the conventional traditional Chinese medicine preparation method. The traditional Chinese medicine composition can be prepared into any commonly-used oral preparation by using the conventional traditional Chinese medicine preparation method. The invention can obviously improve the intense pain, obstructs the canceration of liver tumor cells, interdicts the reproduction of tumor cells, recovers the activity of liver cells, enhances the self-repairing function of the liver, resists the diffusion and prevent the metastasis, obviously shrinks the liver tumors, relieves and eliminates the ascites, improves the life quality, prolongs the life, relieves patient&#39;s pain and increases the appetite. The traditional Chinese medicine composition has exact and obvious clinical curative effect of improving the overall disease resistance.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a biodegradable biopolymer material having excellent biochemical properties, a method for the production of the material and a functional material composed of the polymer material.  &lt;P&gt;SOLUTION: The biopolymer material is composed of a simple silk fibroin or a composite material of a silk fibroin derived from domesticated silkworm or wild silkworm and the 2nd substance selected from cellulose, chitin, chitosan, chitosan derivatives, wool keratin and polyvinyl alcohol. The material is biodecomposable by proteinase, etc. A film of the biodegradable biopolymer material is formed by coating a substrate with a mixture of an aqueous solution of a silk fibroin derived from domesticated silkworm or wild silkworm and an aqueous solution of the 2nd substance and solidifying the applied solution by evaporation to dryness. The mixture of the aqueous solutions is prepared by setting the concentration of each aqueous solution to 0.1-5 wt.% and uniformly mixing the solutions under stirring taking care of not to cause the precipitation and coagulation reaction.  &lt;P&gt;COPYRIGHT: (C)2004,JPO
Isolation comprises incubating low-density lipoprotein (LDL) receptors with a labelled form of a ligand (I) in the presence of the test substance, and measuring the deg. of binding. (I) is material from a rhino-virus of the &#39;small rhino-virus receptor gp.&#39; (J.Virol.,51,340,1984). Also claimed are the use of (I) for inhibiting the binding of physiological LDL ligands; a method for determining LDL receptors, comprising labelling (I), incubating it with the test sample, and measuring the deg. of binding of the labelled (I); and a method for delivery of a therapeutically active substance (II) into cells bearing LDL receptors, comprising coupling (I) with (II) to form a conjugate, and supplying the conjugate to the corresp. cell material. USE - The 1st method may be used to screen for substances capable of inhibiting binding of rhinoviruses or other ligands to LDL receptors. Method 2 may be used for the analysis, e.g., of cholesterol metabolism.
&lt;P&gt;PROBLEM TO BE SOLVED: To provides peptides that stimulate release of arachidonic acid in target cells and peptides inducing release of calcium in cells.  &lt;P&gt;SOLUTION: The present inventors have identified 24 peptides that participate in arachidonic acid release in neutrophil-like differentiated HL60 (dHL60) cells, and found that these peptides act as chemotactic substances for human phagocytes. Several peptides binds to the formyl peptide receptor-like 1 (FPRL1). Some of the peptides are also bound to other receptor(s) expressed in HL60 cells. In addition, each peptide can stimulate shared and distinct intracellular signaling pathways.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
NEW MATERIAL:The compound of formula I [X is Ala or Thr; Y is cyclic amino acid residue of formula II (A is S or methylene; n is 0 or 1); Z is mercapto-protecting group] and its salt. EXAMPLE:The compound of formula III. USE:A remedy for osteoporosis, Bechet&#39;s disease of bone, hypercalcemia, etc. It lowers the Ca&lt;2+&gt;-concentration in serum and has high stability and biological activity. PREPARATION:Pro which is the C-terminal amino acid of the objective calcitonin derivative is bonded to an insoluble resin (preferably benzhydrylamine resin, etc.). Protected amino acids are successively bonded to the C-terminal side according to the amino acid sequence of said derivative. Finally, the resultant protected peptide resin is subjected to final deprotection reaction by treating said resin with hydrogen fluoride, etc.
Materials and Methods related to Dickkopfs and Neurogenesis Abstract Methods for promoting dopaminergic neuronal development and producing neural cells having a dopaminergic phenotype. Dopaminergic neural cells may be used for treating individuals having a neurodegenerative disease such as Parkinson&#39;s disease. Dopaminergic cells may be implanted into the brain of the individual, and/or dopaminergic neural development may be induced or enhanced in the brain of the individual. Methods comprise treating the cell with a Dkk ligand, such as any one of Dkk1 to Dkk4 or a fragment thereof comprising a cysteine rich domain, or a Dkk receptor such as LRP5 or LRP6, thereby producing or enhancing proliferation, self-renewal, survival and/or dopaminergic induction, differentiation, survival or acquisition of a neuronal dopaminergic phenotype. The cell may be co-cultured with astrocytes or glial cells and may be contacted with an FGF growth factor. Dopaminergic neurons may also be useful in drug/toxicology testing and for target development or drug discovery.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an excellent antibacterial agent manifesting a specific antibacterial activity to Propionibacterium acnes.  &lt;P&gt;SOLUTION: The invention relates to the antibacterial agent based on a discovery that a tocopheryl phosphate and/or its salt manifest the specific antibacterial activity to the Propionibacterium acnes. The antibacterial agent containing tocopheryl phosphate and/or its salt manifest an excellent antibacterial activity to acne bacteria which is bacteria causing pimple. The antibacterial agent manifests a synergy effect by using with another kind of antibacterial agent. The antibacterial agent manifests an ameliorating effect on pimple in a practical test on the people with pimples. The antibacterial agent can be used for a cosmetic, a quasi-drug, medicine.  &lt;P&gt;COPYRIGHT: (C)2006,JPO&amp;NCIPI
The patient-centric eco-system operates in healthcare facility&#39;s (HC-FAC) treatment/recovery/waiting rooms using audio/visual (presence) sensors and image sensors (serial static images or video). Sensors capture patient presence sensory data in rooms. Computing devices process data and obtain room-to-room patient unique transition data, patient unique treatment/recovery timing data, and treatment/recovery image data. System digitally tags and segments the treatment/recovery images (serial static images or video) to generate time-stamped patient unique treatment/recovery image data which is serial static images or video clip(s). Patient/provider replay command displays processed images or video clip. The display may be on a multimedia medical documentation presentation platform. To monitor and track patient flow through HC-FAC, a basic process flow user interface (UI) is a 3-column display (arrivals, treatment/recovery and check-out) tracking all patients at the HC-FAC with patient-display tiles manual/auto moved column-to-column as each patient transitions through HC-FAC.
PURPOSE:To carry out fine granulation in water solvent and formation of capsule walls simultaneously by preparing fine capsules using self-dispersive resins which have dispersibility to disperse themselves to the degree to give average grain size smaller than a specific size under the function of water solvent. CONSTITUTION:Fine capsules consisting of a hydrophobic liquid and/or a solid substance (e.g. pigment) and a resin with which they are enclosed are manufactured. At that time, using self-dispersive resins (e.g. urethane resin) which has dispersibility to disperse themself to the degree to give &lt;=0.1mum average grain size, fine capsules are prepared and fine granulation in water solvent and formation of capsule walls are carried out simultaneously. The super fine granular capsules prepared by the method can be formed easily within a short time without using auxiliary materials such as surfactants, etc., and have &lt;=0.1mum average grain size. The capsules are especially applicable for recording materials such as pigments, inks, etc., and cosmetics and dyes for fibers.
NIH 0 NH HN 0 N N I. Amid linkage H Hu- R R R 1l. Unsubstituted metal binding enterobachn I triscatecholate sideropohre 2 (R= H or Ac) oran Trarsaportdiated Dug D9eivery C IiV ~)OI~t dd(~II~ Am#001Ad snd AmaxkUiln Affdn~p@WrIJIn Cooqiupaieo Ahfi&#39;psuadomomi V10,f 00 MRl And-psadimww KMCm4O54JO p Figure 1 An artificial tris-catecolate siderophore with a tripodal backbone and its conjugates with ampicillin and amoxicillin were synthesized. Both conjugates exhibited significantly enhanced in vitro antibacterial activities against Gram-negative species compared to the parent drugs, especially against P. aeruginosa. The conjugates appear to be assimilated by an induced bacterial iron transport process as their activities were inversely related to iron concentration. The easily synthesized tris catecolate siderophores can be used with a variety of drugs as conjugates to target antibiotic-resistant Gram-negative bacteria.
The subject matter disclosed herein provides methods for presenting glucose level data. Glucose data for a patient may be received. A current glucose level and a rate of change of the current glucose level may be determined based on the received glucose data. A first interface may be displayed on a screen of a device. The first interface may include a unitary icon. The unitary icon may display the current glucose level and a visualization of the rate of change. Related apparatus, systems, techniques, and articles are also described. &lt;000 Con fn: L 0 WnU 0Ow 0 0 = D 0 0 &gt; _U ZwU C - 0 .C LUJ w C
PURPOSE:To obtain the title substance useful as remedy or diagnostic medicine at a short time in high yield, by reacting an iodinated aromatic compound with a radioactive alkali metal iodide in the presence of ammonium sulfate and copper sulfate under acidic condition. CONSTITUTION:An iodinated aromatic compound (e.g. m-iodobenzylguanidine or iodophenyl fatty acid) is blended with a radioactive alkali metal iodide (e.g., Na&lt;123&gt;I, Na&lt;125&gt;I or Na&lt;131&gt;I), ammonium sulfate and copper sulfate and the reaction mixture is concentrated and dried by heating or under reduced pressure and further heated to carry out exchange reaction of iodine with radioactive iodine and provide the title substance. The above-mentioned reaction is carried out in reaction conditions of 110-150 deg.C and 30-60min. The above-mentioned method is advantageous in mass production of the aimed product having short half-life, since label ratio is not lowered even in large scale of &gt;=500m Ci. Further the administration is minimized, because the aimed product having extremely high specific radioactivity is obtained.
Petrolatum Composition and Process For Its Manufacture Petrolatum based compositions (i.e., composition in which the emollient petrolatum comprises greater than or equal to 50% of the composition) are desirable because of the excellent moisturization properties provided by petrolatum. However, it has sensory negatives perceived by consumers. Specifically, because of the oily/greasy and &#34;tacky&#34; (i.e., slightly adhesive or gummy to touch) feel, petrolatum has certain limits to the scope of application. We have found a way to overcome this problem using a copolymer which furthermore avoids the undesirable use of additional oil. A composition is therefore provided comprising: i) 50% to 99.95 % by weight petrolatum; ii) greater than 0.05% by weight of a copolymer bearing greater than 70% long chain alkyl. said composition having an enthalpy of between 30 and 65, preferably 40 and 60, even more preferably 45 and 55 J/g, the petrolatum number average crystal size being less than 10 μm, preferably less than 5 μm, more preferably less than 1 μm.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide devices and methods for preventing formation of scar tissues and/or adhesion subsequent to surgical treatment, an injury, or a wound.  &lt;P&gt;SOLUTION: The invention includes various devices and methods, in which antiproliferative chemical having cytostatic performance is provided between internal tissues solely or with other medicine for preventing formation of scar tissues and/or adhesion during treatment of a wound or other surgical part. The devices for achieving above dosage include permanent implant or biolytic material including antiproliferative chemical such as sirolimus attached to it, but they are not limited to these. The antiproliferative chemical includes antiplatelet agent, antithrombotic agent, or anticoagulant agent, and may be used with other chemical that is not limited to them. The methods for alleviating formation of scar tissues and/or adhesion, or adhesion at an inosculation part are also provided. The antiproliferative chemical having cytostatic performance is dosed for arteriovenous shunt inosculation to a patient of an end-stage renal disease.  &lt;P&gt;COPYRIGHT: (C)2009,JPO&amp;INPIT
FIELD: oral care. ^ SUBSTANCE: tooth foaming fluorinated complex which contains the aqueous solution of the surface active component chosen from the group of non-ionic surfactants, zwitterionic surfactants, betain surfactants and their mixtures. Surface active components constitute from 0.1 to 3 mas.% per complex mass. Besides, the complex contains acidifier safe for oral administration. It consists of apple acid in quantity sufficient for the complex pH regulation from about 3 to 5. The complex while feeding makes the foam which disappears less than in 120 sec. The complex is stable in case of low temperature and is a clear solution that for the most part doesn&#39;t contain contaminants in case of holding for 12 hours at 4.4C. While splitting from the container to the cell of the tooth tray the complex makes fast-falling foam of low density that condenses in 1 minute after the splitting of the complex from the container and its contact with the patients&#39; teeth. ^ EFFECT: invention strengthens teeth. ^ 16 cl, 3 tbl, 3 ex
PURPOSE:To obtain a dental soft magnetic alloy suitable for plugging, orthodontics, etc. in combination with a permanent magnet by alloying Co and Au in a specified ratio. CONSTITUTION:To a Co-Au alloy consisitng of 15-70wt% Co and the balance Au is added &lt;=5% one or more among Mn, Zn, Sn, Al, Si and Mg as a deoxidizer. Dental root 2 remaining in gum 1 is plugged up with the resulting soft magnetic dental alloy 3, and rare earth element - Co magnet 5 is buried in crown 4 so that one magnetic pole of manget 5 is faced to alloy 3. Thus, alloy 3 and magnet 5 in crown 4 are fixed by magnetic attraction. Since alloy 3 contains the deoxicizer, a blow hole-free casting is obtd. and it can be used widely for a full denture, a partial denture, a bridge, a crown, an inlay, etc.
A container (1), designed to be retained in contact with a patient&#39;s skin to administer a homeopathic treatment by the transmission of negatively charged electrons, is made from a supple, transparent but colored plastic material. It comprises lower (2) and upper (3) compartments linked through a narrow neck (4) that allows a solution to pass from one to the other. The container (1), designed to be retained in contact with a patient&#39;s skin to administer a homeopathic treatment by the transmission of negatively charged electrons, is made from a supple, transparent but colored plastic material. It comprises lower (2) and upper (3) compartments linked through a narrow neck (4) that allows a solution to pass from one to the other. The neck has a cross-section of at least one square cm, while the neck (7) of the upper compartment is closed by a stopper (6) which is sealed after filling. The container can be shaped according to the part of the body to be treated, e.g. in the shape of a shoe insole to treat the foot, and solid portion of the container or adjacent membrane (9) has holes (8) for a fastening cord.
A computerized checklist system for use in the medical field preferably comprises a checklist unit adapted to be held in an operator&#39;s hand and a cradle for supporting the checklist unit. Each of these components includes a microprocessor for controlling the operation thereof. An optical link is provided to transmit data between the devices. The checklist unit includes suitable memory for storing alphanumeric checklist data including a sequence of checklist items. A display and a voice synthesizer selectively output checklist items. The checklist unit includes a keypad having a plurality of control switches for enabling an operator of the checklist unit to enter one of a plurality of signals indicating that the operator has taken one of a plurality of predetermined actions in response to each checklist item outputted by on the display and/or spoken by the voice synthesizer. The handheld unit also includes a program, responsive to processing of the checklist items during a work session, for storing a session log, the session log including data identifying each checklist item outputted during the work session, the signal entered by the operator in response to each checklist item, and a time when such signal was entered by the operator. Following placement of the handheld unit in the cradle after the work session, the session log data is downloaded to the cradle and then printed in a predetermined format.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a new agent for increasing adiponectin amount in blood and a preventing or improving agent for arteriosclerosis, diabetic and metabolic syndrome, to provide foods and drinks, medicines, cosmetics or the like containing these agents.  &lt;P&gt;SOLUTION: The agent for increasing adiponectin amount in blood, containing proanthocyanidin as an active ingredient is provided. The preventing or improving agent for arteriosclerosis or diabetic caused by hyposecretion of adiponectin is provided. The preventing or improving agent for metabolic syndrome is provided. And foods, medicines and cosmetics containing the same are also provided.  &lt;P&gt;COPYRIGHT: (C)2006,JPO&amp;NCIPI