anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
A personal body treatment product is disclosed for application to a user&#39;s body for hygienic, cosmetic, therapeutic, wellness purposes. The product includes a salt/mineral mass having salts and/or mineral ingredients capable of dissolving or dislodging from the mass in water at different rates. A sheath in the form of a bag encloses the mass, the sheath being composed of a porous material enabling water to penetrate the sheath so as to dissolve and/or dislodge ingredients of the mass and to enable ingredients to pass through the sheath to contact the user&#39;s body. The sheath encloses the mass so that the surface of the mass is not exposed in a manner to directly contact the user&#39;s body in use. The salt/mineral is composed of natural salts/minerals in a naturally adherent mass which is mined or harvested and subsequently shaped into a bar with rounded edges or corners, the bar being of a size to be comfortably grasped and held by hand. The sheath is made of a micromesh material so that substantially insoluble particulates in the mass and/or sparingly or relatively slowly soluble ingredients in the mass cannot pass through the micromesh material in particulate form to cause discomfort if rubbed along the user&#39;s skin. There is also provided a method of personal body treatment by providing and using the product.
The invention provides a means of closed exchange of implanted medical device components. An exchanger is brought into contact with the implanted medical device &#34;in situ&#34;. The component is withdrawn from the implanted device and brought into a closed chamber of the exchanger. Without breaking the contact between implanted device and exchanger, the replacement component is then moved from its position in the exchanger, and inserted into the correct position in the implanted device. The surfaces of the implanted device are not brought into contact with the outside environment, thereby minimizing the possibility of introducing contaminants into the body during the exchange process. The invention is particularly useful for devices that are difficult to position and reposition, thus making it advantageous to exchange only an expended component, rather than the entire device.
1441136 Thixotropes CHESEBROUGHPONDS Inc 4 Sept 1973 [2 Nov 1972] 41562/73 Headings C3F C3P and C3R [Also in Division C4] A coating composition in the form of a gel capable of being broken up for application to a suitable substrate by a relatively small shearing force at a relatively small shearing rate, includes a rheological control system comprising an amine-modified montmorillonite clay, a swelling agent therefor, and a non-volatile oleaginous wetting agent having polar groups and an affinity for wetting clay selected from oils, waxes and mixtures thereof. The compositions may be nail enamels or polishes, paints, inks or aerosol paints. The wetting agent may be polymerized or copolymerized castor oil or a modified oxidized wax. The swelling agent may be orthophosphoric acid. In the examples there are prepared nail enamels or polishes comprising camphor, dibutyl phthalate butyl acetate, ethyl acetate, isopropyl alcohol toluene, nitrocellulose, aryl-sulphonamide resin, dimethyl dioctadecyl ammonium montmorillonite, mixed oxidized polyethylene modified wax, cosmetic oxide, iron blue, titanium dioxide, D &amp; C Red No. 6 Al, orthophosphoric acid, ethyl alcohol, acetyl tributyl citrate, polymerized castor oil, D and C Yellow No. 6 Al lake, D and C Red No. 6 and 7 Ca lake, unpolymerized castor oil and pearl essence pigment guanine fish scale, non-aqueous paint compositions comprising titanium dioxide, mineral spirits, alkyd resin, dimethyl dioctadecyl ammonium montmorillonite, mixed oxidized polyethylene modified wax, lead naphthenate, cobalt naphthenate, orthophosphoric acid, methyl methacrylate, cellulose acetate, acetate, toluene, butyl benzyl phalate and polymerized castor oil; inks comprising benzyl dodecyl dimethyl ammonium montmorillonite, polyethylene modified wax, butanol, nitrocellulose, titanium dioxide, ethyl alcohol, n-butyl acetate, dibutyl phthalate, ethyl acetate, phthalocyanine blue, n-propyl alcohol, polyamide resin, mixed oxidized polyethylene modified wax and naphtha; and aerosol paint lacquers comprising nitrocellulose, isopropyl alcohol, methyl-butyl methacrylate, titanium dioxide, dibutyl phthalate, toluene, ethyl acetate, butyl acetate, dimethyl dioctadecyl ammonium montmorillonite, mixed oxidized polyethylene modified wax, polymerized castor oil, trichlorofluoromethane and dichlorodifluoromethane.
&lt;P&gt;PROBLEM TO BE SOLVED: To obtain a moisture retention vegetable extract keeping the moisture retention effect over a long period, and obtain a moisture retention agent for external use, a cosmetic, a bathing agent and a detergent composition each containing the extract.  &lt;P&gt;SOLUTION: The moisture retention vegetable extract is composed of an extract of a mixture of Cinnamomum cassia, Poria cocos, Paeonia lactiflora, Gprunus persica, Paeonia suffruticosa and Coix lacryma-jobi Linne var. ma-yuen. The moisture retention agent for external use, the cosmetic, the bathing agent and the detergent composition contain the extract. A medicine obtained by decocting a mixture of the above herb drugs at specific ratios has the same composition as a Chinese medicine called as Keishi-Bukuryo-Ganryouka-Yokuinin believed to be effective for irregular menstruation, hysterics, acne, spot and chapped skin of hands and feet by internal use. The extract of the herb drug mixture contains a moisture retention vegetable component continuing the moisture retention effect for a long period and is effective for the prevention, amelioration or improvement of dry skin, roughened skin. chap, kibe, dandruff, itchiness and inflammatory diseases, and also for the treatment of dry hair, loose hair, split hair and cut hair and the application of luster to the hair by external use.  &lt;P&gt;COPYRIGHT: (C)2004,JPO
PURPOSE:To form a sugar-coating layer having excellent disintegrability and impact resistance in a short time, by adding lactose and optionally talc, etc., to an aqueous medium containing dissolved hydroxypropyl cellulose, etc., and carrying out the intermediate coating of a tablet with the obtained suspension. CONSTITUTION:0.05-0.2pts.wt. of hydroxypropyl cellulose and/or hydroxypropylmethyl cellulose is dissolved in an aqueous medium composed of 0.5pts.wt. of water. 1pt.wt. of lactose and optionally one or two substances selected from talc, precipitated CaCO3, CaSO4, etc., are added to the above solution to obtain a suspension. Intermediate coating of a sugar-coated tablet is carried out by the use of said suspension at a liquid temperature of &lt;=35 deg.C. The above aqueous medium may contain an organic solvent such as ethanol at an amount of &lt;=40%, preferably &lt;=30%. There is no problem of ignition hazards, etc., because an organic solvent is not used or only an extremely small amount of an organic solvent is used in the present process. The tablet can be advantageously applied to a patient of diabetes since the amount of sucrose is remarkably reduced in the coating layer.
PURPOSE:To obtain an analgesic and antiinflammatory drug useful for mammal containing human effectively prevent disease of tunica mucosa ventriculi, containing ascorbic acid, analogues of said acid and aspirin analogue compound, etc. CONSTITUTION:At least, a species of ascorbic acid and analogue of said acid and at least a species of aspirin analogue compound are contained in the objective drug. An inorganic salt of ascorbic acid, fatty acid ester of ascorbic acid or inorganic acid ester of ascorbic acid is used as the ascorbic acid analogue and acetyl salicylic acid, aluminum acetyl salicylate, choline salicylate or sodium salicylate, etc., is used as the aspirin analogue compound. Besides, &gt;=0.1 pt.wt. ascorbic acid or analogue of said acid is used to 1 pt.wt. the aspirin analogue compound.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a dental practice support device capable of easily displaying an X-ray image of the tooth of a desired site of the teeth within an oral cavity (by a single click).  &lt;P&gt;SOLUTION: An oral cavity immediate display screen 140 having an oral cavity immediate display area 145 displaying each tooth within the oral cavity by an illustration (icon) is displayed on a monitor device. X-ray images of teeth of each patient are managed in an image database in association with patient identification information and teeth sites. When an icon showing the site of a desired tooth within the display area 145 is clicked, viewer software is started to display an image display screen 150. The X-ray image of the corresponding site of the patient is acquired from the image database based on the patient identification information and the tooth site shown by the icon, and the acquired X-ray image is displayed on the image display screen 150.  &lt;P&gt;COPYRIGHT: (C)2005,JPO&amp;NCIPI
&lt;P&gt;PROBLEM TO BE SOLVED: To provide methods and compositions that are usable for treating various pathologic conditions including generation errors in vascular growth or hematopoiesis, and pathologic conditions generated from an abnormal number of erythroid cells, or abnormally enhanced vascular growth.  &lt;P&gt;SOLUTION: For uses of modulating hematopoiesis and vascular growth, methods and assays for selecting compounds functionally equivalent to a gene product expressed in an embryo&#39;s extraembryonic tissue are provided. Such compounds are exemplified by hedgehog protein and a hedgehog protein binding receptor. According to this method, at least one of hematopoiesis and vascular growth is caused by undifferentiated mesodermally derived cells. As an example of the undifferentiated mesodermally derived cells, an embryonic explant cell is exemplified.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
PROBLEM TO BE SOLVED: To obtain a cosmetic base comprising polyoxyethylenated polypropylene glycol, not generating a stench when produced and after stored for a long period, and useful as an emulsifier, a humectant, etc. SOLUTION: This cosmetic base comprises polyoxyethylenated polypropylene glycol having a propenyl ether group content of &lt;=0.001 milliequivalent/g. The component A is preferably the ethylene oxide adduct of polypropylene glycol obtained by addition-reacting propylene oxide to a glycol compound in the presence of 0.03-3 wt.% of potassium-based and/or cesium-based catalyst (for example, potassium hydroxide or cesium hydroxide) at a temperature of 60-90 deg.C. After subjected to the removal of the catalysts and to the neutralization of the product, the obtained component A is stored. The number-average mol.wt. of the polypropylene glycol portion in the cosmetic base is preferably 1,500-4,500.
PURPOSE:To obtain a tablet resistant to coagulation even under a low pH condition, and dissolving rapidly in gastric juice to solubilize the active component, by compounding a sucrose fatty acid ester containing more than a specific amount of a monoester. CONSTITUTION:A sucrose fatty acid ester containing &gt;=90% monoester and preferably containing a 8-22C fatty acid such as octanoic acid, lauric acid, stearic acid, oleic acid, etc., as the constituent fatty acid, is used as a component of a tablet at a ratio of &gt;=50wt%. The dissolution of the active component in the gastric juice can be accelerated and the quick drug action can be attained by this method. Sucrose fatty acid ester is a nonionic surfactant having high safety, and is used widely in the fields of food, medicine, and cosmetic. Conven tional sucrose fatty acid ester forms a coagulum at a low pH and loses its dispersing power and solubilizing power. In contrast to the above, its monoester does not cause the coagulation even in a low pH region and has excellent solubilizing power to a water-insoluble component.
The present invention relates to ointment for treating burns and scalds and a preparation method thereof, which belongs to the field of Chinese medicine. The ointment mainly solves the problems of the existing similar medicine of slow marked effect and inexhaustive cure. The ointment is prepared from the following components (parts by weight): 400 to 500 parts of sesame oil, 100 to 110 parts of beeswax, 35 to 40 parts of violet chrysanthemum ligaloes powder 20 to 30 parts of dragon&#39;s blood and 0.5 to 1 part of musk powder through medicine refinement. The preparation method comprises the medicine refining steps: a. the components are prepared; b. after the superior sesame oil is put in a copper pan to be heated by warm fire to 100 to 130 DEG C and the beeswax is added for dissolution, a plastic plate is used for agitation and continuous heating for 2 to 3 min, the violet chrysanthemum ligaloes powder is added to be heated for 6 to 15 min, the dragon&#39;s blood and the musk powder are added to be heated for 30 to 35 min, and the fire is extinguished so as to obtain the ointment. The ointment has the advantages of obvious effect, thorough cure and no scars, and patients basically have no pain. The ointment is mainly used for treating patients with burns and scalds.
An improving program for malabsorption of tract of intestines and stomach includes mainly original taste plum, syrup, flavoring powder, and lactic acid bacterial powder. The original taste plum is obtained by adding edible salt to preserve green plums, exposing to the sun, and adding sugar to preserve for several days. The syrup is made by allocating a fixed ratio of water, sugar, Pu&#39;er tea, and cassia tora seed. The flavoring power is made by grinding chitin, hawthorn fruit, and senna leaf tea into powder first, and then mixed and agitated according to an appropriate ratio. The lactic acid bacterial powder is made from an active fungus body, which can metabolize the carbohydrate and produce more than 50% lactic acid bacteria. The problem for the malabsorption of tract of intestines and stomach can be improved by eating the invented product that has the advantages to discharge the filth adhered on the tract wall of intestines and stomach, increase the creeping motion of intestines and stomach, and making the intestines and stomach increased the absorption of ingested nutrient.
FIELD: medicine. SUBSTANCE: active food additive of animal origin is perorally used together with Pevzner&#39;s diet N 5. The additive is prepared of the gastric cuticles of domestic hens. It is administered internally in combination with intakes of magnesium oxide. According to research findings this method reduces the diameter of the gallbladder concrement from 21 down to 7 mm, that is by three times, after 7 months of treatment. EFFECT: lower rate of side-effects and complications in the therapy of cholelithiasis and simplification and lower cost of treatment. 4 cl
Sterile, injectable therapeutic compositions comprise an injectable liquid carrier containing microscopic, medicament-containing capsules produced by liquid-liquid phase separation.  Suitable encapsulating materials include gelable hydrophillic colloids e.g. gelatin, albumin, fibrinogen, casein, agar, sodium oleate, pectin and ichtlyocolla which may be used alone or together with other colloid materials of opposite charge e.g. gum acacia, sodium carboxymethylcellulose, sodium alginate and cellulose-, amylose- and starch acetate phthalates and &#34;linear macromolecular synthetic polymers&#34; i.e. materials whose structure comprises both lipophilic and hydrophilic units e.g. those derived from styrene, and an alkyl ring-substituted styrene or an ether- or ester-substituted ethylene and those derived from maleic, crotonic or acrylic acids or maleic acid or acrylic acid amides respectively.  Examples of such polymers are styrene-maleic acid and styrene-maleic acid copolymers, sulphonated polystyrenes, polymethacrylic acid and vinyl ether-maleic acid copolymer.  The particles to be encapsulated may be solid, liquid or emulsion particles having either hydrophilic or lipophilic surface characteristics and the encapsulation may be achieved by any suitable liquid/liquid phase separation process e.g. those disclosed in Specifications 751,600, 911,483, 929,402, 929,408 and 929,409. The capsules may be hardened by chemical or physical means e.g. irradiation and their components may be sterilized by conventional techniques e.g. by heat, disinfecting gases or irradiation and the encapsulation process may be carried out under aseptic conditions. Specific examples relate to medicaments comprising solutions of testosterone propionate and 6 - methyl - D 1 - hydrocortisone - 21 - acetate in cottonseed oil encapsulated in gelatin/acacia, and a cottonseed oil-in-water emulsion containing methyl salicylate in the aqueous phase and D 1-hydrocortisone acetate in the oil phase encapsulated in gelatin/styrenemaleic acid copolymer.
The present invention discloses a formula of a preparation for blackening hair and a preparation method thereof. The preparation is prepared from raw materials of black-bone chicken, aloe, ginseng, male moth, desertliving cistanche, red sage root, epimedium herb, taurine, seal&#39;s genitals, fineleaf schizonepeta herb, honey, ledebouriella root, fleeceflower root, sucrose, spine date, black ant, ethanol with a concentration of 65%, ethanol with a concentration of 40%, distilled water, etc. which are prepared into a composition of water solution by the technologies of mixing, stirring, filtering, etc. The present invention is suitable for hair and scalps with various characteristics. After the present invention is used for cleaning hair, no anaphylactic reaction occurs, the present invention has no toxic or side effect, and the medicine rapidly penetrates the skin and is absorbed by the skin, so the purpose of blackening hair is realized. The present invention has obvious and good effect on blackening hair, low cost and simple and practical preparation technology.
The present invention provides a single-stranded antisense oligonucleotide or a pharmaceutically acceptable salt thereof for regulating the expression and/or function of the RPS25 gene. In the single-stranded antisense oligonucleotide, each nucleotide is bonded by a phosphate group and/or a modified phosphate group. The single-stranded antisense oligonucleotide includes a gap region, a 3&#39; wing region bonded to the 3&#39; terminal of the gap region, and a 5&#39; wing region bonded to the 5&#39; terminal of the gap region. The gap region is a deoxyribose-constituted nucleic acid in which a sugar-moiety-modified nucleic acid may be included. The 3&#39; wing region and the 5&#39; wing region are modified nucleotides. The single-stranded antisense oligonucleotide has a base length of 12-30 mer. The base sequence of the antisense oligonucleotide is: a base sequence having a sequence identity of 90 to 100% inclusive with a base sequence that is complementary to at least one target region constituted at the same base length as the antisense oligonucleotide in the base sequence shown in SEQ ID NO: 1 or SEQ ID NO: 2; a base sequence that is complementary to a base sequence obtained by deleting, substituting, inserting, or adding one or more bases in the target region; or a base sequence that hybridizes at a stringent condition with respect to an oligonucleotide having the above target region.
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to experimental surgery. Use the device for the injury of small laboratory animals by the &#34;blow&#34; mechanism, namely the traumatic impact of a cargo weighing 425 g, which falls from a height of 28 cm and transfers its energy to the anterior abdominal wall of a laboratory rat weighing 360–390 g, lying in a supine position with the orientation of the center of the shock pad with a diameter of 3.5 cm 5 mm to the right and above the tip of the xiphoid process. 1 ml of blood is taken from the carotid artery immediately before the injury and 60 minutes after it for 1 minute, which simulates excessive bleeding from the liver vessels immediately after the injury and its amplification during laparotomy, when a revision of the abdominal cavity is performed. Necessity of such sampling is dictated by the faster formation of fibrin in rats and, as a consequence, an earlier stop of bleeding compared with a human, even with massive liver damage. First 20 minutes after the injury simulate the situation of waiting for medical care to the victims, so there is no fluid resuscitation, which corrects hypotension. Prehospital phase is modeled from 20 to 60 minutes, when the patient receives infusion therapy with maintaining systolic blood pressure at the level of 80–90 mm Hg and is delivered to the hospital. By the 60minute, a laparotomy is performed, and one or another surgical technique is performed. Study of the hemostasis system showed the presence of coagulopathy after such an injury by 60minute.EFFECT: method allows to create a model of a closed blunt severe liver injury with coagulopathy in small laboratory animals, which is closest to the real situation in life.1 cl, 1 ex
&lt;P&gt;PROBLEM TO BE SOLVED: To obtain a composition in the oral cavity having excellent prophylactic effects and inhibitory effects on mouth odor and high persistence of the effects.  &lt;P&gt;SOLUTION: This composition in the oral cavity affords combined effects on scavenging of the mouth odor with a plant of the family Labiatae or its extract and inhibition of metabolism of causative bacteria of the mouth odor with a seed of a plant of the genus Zanthoxylum of the family Rutaceae or its extract and has the high inhibitory effects on the mouth odor and excellent fast-acting properties and persistence. The composition is obtained by formulating the plant of the family Labiatae or its extract and (B) the seed of the Zanthoxylum piperitum or its extract. Furthermore, a prophylactic preparation for the mouth odor is prepared by formulating one or two or more species of a plant of Cola acuminata and Cola nitida A. Chev. of the family Sterculiaceae or its extract, menthol and its derivative, a sweetener and a perfume, which has an improved taste.  &lt;P&gt;COPYRIGHT: (C)2006,JPO&amp;NCIPI
The invention relates to a traditional Chinese medicine composition for treating constipation caused by Parkinson&#39;s disease, which is prepared from the following raw material medicines in parts by weight: 30 parts of Chinese yam, 30 parts of medlar, 15 parts of cistanche, 18 parts of radish seed, 12 parts of roasted malt and 15 parts of kudzu root powder. The invention also comprises application of the traditional Chinese medicine composition in preparing a medicine for treating constipation caused by Parkinson&#39;s disease. The traditional Chinese medicine composition is taken 5-7 points in the morning every day. Its advantages are: 1. the selected raw material medicines are homologous in medicine and food, the number is small, the preparation method is simple and convenient, the raw material medicines accord with the compatibility principle of &#39;monarch, minister, assistant and guide&#39;, the medicines are combined, and the effects of tonifying kidney and replenishing essence, nourishing yin and softening liver, and relaxing bowel are achieved. 2. The time of taking the medicine is Mao, which reflects the rule of &#39;treating with time&#39;. 3. The optimal weight part ratio of the raw material medicines is obtained through experimental screening, the curative effect is good, no side effect is caused, and the application prospect is good.