anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
1,161,491. Herbicides containing fluoropyridines. IMPERIAL CHEMICAL INDUSTRIES Ltd. 9 Aug., 1966 [19 Aug., 1965], No. 35596/65. Heading A5E. [Also in Division C2] Herbicidal compositions comprise as .an active ingredient a compound of the general formula . where R 3  and R 5 , which may be the same or different, are atoms of fluorine or chlorine and either (a) R 6  is an atom of fluorine or chlorine and R, is an group, on acytoxy group or an acylthio group, the term acyl being as defined below, or (to) R 4  is an atom of fluorine or chlorine and R 6  .is an hydroxyl group, or a salt of any of the foregoing compounds wherein R 4  or R 6  is an hydroxyl group, together with a carrier for the active ingredient comprising a solid diluent, or a liquid diluent containing a surface active agent. The term &#34;aryl&#34; denotes the groups -CO.X, -SO 2 .X and -P(=Y)XZ wherein Y is oxygen or sulphur and X and Z are monovalent organic hydrocrabron or substituted hydrocarbon groups. Specified solid diluents are powdered kaolin, Fuller&#39;s earth, gypsum, chalk, Hewitt&#39;s earth and china clay. The preferred liquid diluent is water, and in these compositions the active ingredient is present as solid particles or as droplets of a solution of the active ingredient in a water insoluble solvent. These water-based compositions Imay be obtained by dilution or dispersion of a concentrate, the concentrate being (a) an aqueous dispersion of the active ingredient and containing a &#39;surface active agent and a suspending agent, (b) a wettable powder containing the active ingredient and a solid surface-active agent with or without additional solid diluent, or (c) a solution of the active ingredient, with or without a surface-active agent, in an organic solvent. The compositions may contain additional active ingredients, paraquat and diquat being specified. The compositions may be employed as pre- or postemergence herbicides, and are also stated to exhibit pesticidal, fungicidal, nematocidal and plant growth regulating activity. The invention also comprises a method of combating unwanted vegetation which comprises applying to the locus of the unwanted vegetation or &#39;of seeds thereof a herbicidal composition containing as an active ingredient 2,6-difluoro-3,5-dichloro-4-hydroxy-pyridine or a salt thereof.
PURPOSE:To obtain a therapeutic agent of athlete&#39;s foot containing methyl salicylate, l-menthol, dl-camphor, chlorpheniramine maleate, thymol, nonylic acid vanillylamide, pyrethrum powder and a squeezed solution of aloe. CONSTITUTION:An amount of 6000mg of methyl salicylate is mixed in 380-400ml acetic acid together with 6240mg of l-menthol, 6240mg of dl-camphor, 120mg of chlorpheniramine maleate, 840mg of thymol, 12mg of nonylic acid vanillylamide, 14g of pyrethrum dried powder and a squeezed solution of a piece of aloe leaf and stirred to prepare a therapeutic agent of athlete&#39;s foot. Said therapeutic agent is preferably exposed to sunshine for about 60hr. When it is used, washing of lesion with hot or cold water improves curing effect thereof. Next, the lesion is repeatedly dipped in vinegar warmed to a temp. of generating steam and said therapeutic agent is applied, thus capable of enhancing the therapeutic effect. This process is repeated daily twice.
&lt;P&gt;PROBLEM TO BE SOLVED: To enable it to confirm the X-ray interpretation ability of an X-ray interpreter and guarantee the reliability of his X-ray interpretation results.  &lt;P&gt;SOLUTION: The controller of an evaluation server 5 controls the distribution of test images from an image server 4 to an X-ray interpretation device 1, and obtains the information of an X-ray interpretation report on the test images from the X-ray interpretation device 1. The controller reads a word evaluation table, i.e., the information of evaluation standards, from a memory, and grades and evaluates the interpreter&#39;s X-ray interpretation ability by checking up the obtained X-ray interpretation report on the word evaluation table. The evaluation results are output to a monitor, etc. by a display operation.  &lt;P&gt;COPYRIGHT: (C)2008,JPO&amp;INPIT
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a composition for applying to mucous membranes, which improves the wettability of corneal surfaces and contact lens surfaces.  &lt;P&gt;SOLUTION: This composition for applying to the mucous membranes is characterized by containing sodium carboxymethylcellulose and a terpenoid. The composition improves the wettability of corneal surfaces and contact lens surfaces. Thereby, the wettability is maintained, and the touch feeling of the contact lenses are improved. The composition further has an excellent effect for preventing mucosal dryness symptoms such as dry eyes and excellent effects for preventing or improving various diseases caused by dryness.  &lt;P&gt;COPYRIGHT: (C)2006,JPO&amp;NCIPI
1,255,416. Making beadlets. SUMITOMO CHEMICAL CO. Ltd. 7 March, 1969 [11 March, 1968], No. 12246/69. Heading A5B. [Also in Division B8]  Beadlets comprising one or more particles or droplets of a solid or liquid &#34;active&#34; substance encased within a larger particle of a film-forming, gelible, hydrophilic substance are prepared by: i) forming an aqueous emulsion or suspension of the active substance (with or without an emulsifier/supending agent), ii) adding thereto an aqueous solution of a gelable hydrophilic substance, iii) forming a dispersion in this system of a solvent which is immiscible with the aqueous phase of the system with the aid of a surfactant which is added to either phase, iv) converting the dispersion thus obtained to a system wherein droplets of the original emulsion or suspension exist in a continuous phase of the immiscible solvent by addition of further immiscible solvent (same or different) or by raising the temperature or by addition of multivalent metal ions (this step being carried out at a temperature above the gelation point of the hydrophilic substance) and cooling the mixture to below the said gelation point. The beadlets may be washed, hardened and dried by conventional methods and may be employed when a delayed or gradual release of the active substance is desired. A wide variety of active substances, and hydrophilic substances and suitable surface active agents are mentioned and specific examples relate to the encapsulation of vitamin A, #-carotene, linoleic acid, vitamin D 2  (in peanut oil), ascorbic acid (dispersed in edible fat), hydrocortisone acetate, methyl salicylate, peppermint oil, peanut oil, petroleum spirit and trichlorodiphenyl. The preferred gelable substance is gelatin.
The present invention discloses a Chinese medicine composition for treating cough after a common cold and cough variant asthma. The composition is composed of an effective component and/or a carrier which is acceptable on pharmacy, wherein the effective component is mainly prepared by Chinese ephedra, perilla leaf, perillae, earthworm, etc. The Chinese medicine composition is prepared into an optional preparation on pharmacy. The Chinese medicine composition has the obvious functions for relieving cough, resisting phlogosis, relieving asthma, resolving phlegm, supplying immunity, etc. The Chinese medicine composition can enhance threshold of reaction and Dmin of an air passage for acetyl-beta-methylcholine chloride, and can obviously reduce sGrs and peripheral blood EOS, ECP and IL-5. The reduction range is obviously greater than that caused by combination of a fluorine preparation and becotide spray in a control group. Therefore, the Chinese medicine composition can relieve symptoms of patients who cough after a common cold and have cough variant asthma, can greatly improve the patient&#39;s atopia habitus, and can reduce the high reaction and the high sensitivity of the air passage. The present invention simultaneously relates to a preparation method of the Chinese medicine composition.
&lt;P&gt;PROBLEM TO BE SOLVED: To solve problems such that, although conventional toilet articles such as a soap, shampoo, rinse, lotion, bath agent, are blended with a synthetic surfactant, synthetic preservative, or the like, in many cases, for improving cleaning power, skin-penetrating rate and preservation properties, but recently, the risks of the synthetic surfactant or preservative for health and environment are becoming to be watched closely, and at the same time to exhibit the effects of minus ions, minerals and far-infrared light which are conventionally obtained by using tourmaline or wood/bamboo charcoal, more effectively.  &lt;P&gt;SOLUTION: This toilet article is obtained by blending an essence extracted from the fine particles of a &#34;precious stone&#34;(R) (scientific name: Quartz porphyry) which is a natural mineral, with a toilet article base agent. The toilet article exhibits the effects as the toilet article only by a natural surfactant effect without using any synthetic surfactant, and since it has the minus ion effect, mineral effect and far-infrared light effect of the precious stone, it is the toilet article not only considering beauty treatment but also health and environment. Also, there is no need to add the synthetic preservative to the toilet article since it has antiseptic activity. Further, by incorporating platinum which is a precious metal, in the toilet article, it is possible to take minus ion electron into a living body in a good efficiency.  &lt;P&gt;COPYRIGHT: (C)2004,JPO&amp;NCIPI
PROBLEM TO BE SOLVED: To obtain the subject composition which is a nonelution type dental polymer, useful for a dental resin material and capable of manifesting antimicrobial activities only on the surface by including a specific vinylbenzylphosphonium salt-based monomer as an active ingredient therein. SOLUTION: This antimicrobial and dental composition comprises a vinylbenzylammonium salt-based monomer represented by formula I [R&lt;1&gt; to R&lt;3&gt; are each H, a 1-18C alkyl, etc.; X&lt;-&gt; is an anion; (n) is a number or &gt;=1] [e.g. 4-(tri-n-butylphosphoniomethyl)styrene chloride] as an active ingredient. The monomer represented by formula I is obtained by reacting a styrene derivative represented by formula II with a triorganophosphine in the presence of an organic solvent and a polymerization inhibitor at 25-110 deg.C reactional temperature. The amount of the compounded monomer is preferably 0.1-4mol% in the objective composition.
NEW MATERIAL:A peptide having a structural formula I and/or formula II. USE:DNA-synthesis accelerator, growth accelerator, vulnerary preparation, additive for cell culture medium. PREPARATION:For example, beta-casein from human milk is dissolved in 0.02 M aqueous ammonium bicarbonate (pH8.0), combined with a small amount of trypsin to effect hydrolysis at 37 deg.C for 3 hours. The reaction mixture is subjected to reverse-phase chromatography of octylsilane column using 0.1% aqueous trifluoroacetic acid acetonitrile as a mobile phase, and the elution is conducted with a gradient, as the aqueous trifluoroacetic acid is reduced linearly, while the acetonitrile is increased to effect fractionation. Mouse fetal fibroblasts are cultured in the media containing these fractions to determine the incorporation of &lt;3&gt;H-thymidine and collect the fraction of high activity. Then, the fraction is purified by HPLC to obtain the compound of the formula.
FIELD: medicine, resuscitation, surgery. SUBSTANCE: the innovation deals with prophylaxis and treatment of hepatic failure after operations on liver accompanied with acute massive hemorrhage. Solutions are introduced due to their volumetric coefficients, in particular: erythrocytic mass at 0.8 coefficient, freshly frozen plasma 0.86, 10%-albumin solution 1.47, 5%-glucose solution 0.3, by keeping the difference of absolute values of colloid-oncotic and average-capillary pressure being above 0, central venous pressure - at the level of not more than 50 mm water column and heparin at starting dosage of 100 U/kg, in future heparin should be introduced due to coagulogram&#39;s values by keeping total time for blood coagulation for not more than 10 min, fibrinogen concentration of 3.5 g/l, prothrombin time of 18 sec, prothrombin index of 65%, protein concentration of not less than 56 g/l. The present innovation enables to decrease postoperative lethality and improve rheological blood properties. EFFECT: higher efficiency of prophylaxis and therapy. 1 cl, 1 ex, 2 tbl
FIELD: biochemistry. SUBSTANCE: method involves defatting cattle heart, removing ligaments, vessels, milling and blood washing out. Obtained homogenate is extracted with an aqueous solution of the strong acid - 0.10-0.15% sulfuric or 2.0-2.5% trichloroacetic acid at 10-15 C at pH = 3.9-4.2. Extract is alkalinized to pH = 6.8-7.4 and the end product is extracted from extract on carboxylic cationite that is polymer from the order involving copolymer of methacrylic acid with N,N&#39;-hexamethylenedimethacrylamide and copolymer of acrylic acid with divinylbenzene and cationite is used at Na-form. Elusion is carried out with 10-12% ammonium sulfate solution at pH = 9.0-9.8 and inactive proteins were precipitated from eluate at pH = 7.2-7.5 by addition of ammonium sulfate at amount 0.5 g/ml eluate, and cytochrome c is precipitated from supernatant with 20% solution of trichloroacetic acid at cooling. Deposit is dissolved in small water amount and dialyzed against sodium chloride isotonic solution up to the complete SOions removing. EFFECT: improved method of cytochrome c preparing.
PURPOSE:To obtain a color-developing composition composed of an aqueous solution or an alcoholic aqueous solution containing a dimethylalkylamine oxide at a specific concentration, having high safety and stability and usable as a cosmetic, ornament, etc. CONSTITUTION:The objective color-developing composition is composed of an aqueous solution or an alcoholic aqueous solution containing 0.4-2.0wt.% of a compound of formula (R is 16-20C alkyl or 16-20C alkenyl), e.g., dimethylstearylamine oxide. A colorless transparent visco-elastic liquid can be produced by mixing the compound of formula with water at 50-70 deg.C. When the obtained solution is cooled to &lt;=40 deg.C, a liquid crystal having a lamellar structure with a spacing of several thousand Angstrom  is formed to exhibit brilliant color. In some cases, the liquid crystal develops beautiful pearl luster by leaving the crystal at 5-30 deg.C. The interlaminar spacing of the lamellar structure can be freely varied by varying the mixing ratio of the compound to water and the wavelength of the interference light is varied corresponding to the spacing. Accordingly, various colors can be developed by the use of the composition.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a means for easily and reliably preventing an accident that a sample and chart information about an alien living body are falsely recognized as a sample and chart information about the same living body when using an electric chart system in observing a sample by a microscope.  &lt;P&gt;SOLUTION: When a prepared specimen is set on a stage of the microscope 11, the microscope reads a two-dimensional barcode on the prepared specimen and transmits it to a terminal device 12. The terminal device 12 transmits identification information obtained by converting the two-dimensional barcode received from the microscope 11 to a server device 13. The server device 13 searches a database for chart information about a living body corresponding to the identification information received from the terminal device 12 and transmits it to the terminal device 12. The terminal device 12 displays the chart information received from the server device 13. When the prepared specimen is removed from the stage, the terminal device 12 stops displaying the chart information.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
The present invention discloses a method for using sonication to achieve a homogenized blended oil and trans-resveratrol base and functions as a multi-use men&#39;s skin. hair, and anti-aging product for irritated skin. The Trans-resveratrol used in the present disclosure is sourced from Japanese Knotweed,  Polygonum cuspidatum  roots. Trans-resveratrol is a super antioxidant with a high concentration of polyphenols. Trans-resveratrol is derived from the Japanese Knotweed plant and is significantly more potent than the more commonly known, cis-resveratrol. The healing properties of Trans-resveratrol include decreased inflammation, improved cardiovascular health, and anti-aging effects, reduced impact of hangovers and intoxication, increased antioxidants in a person&#39;s blood stream, improved the appearance of complexion, reduced impact on skin from exhaustion or lack of sleep, healed body and muscles after exercise, and reduced impact of stress on body.
A vending machine for dispensing a customized dietary supplement to dialysis patients, is disclosed. The vending machine comprises a serving dispenser designed to hold and distribute the customized dietary supplement to a user. The vending machine further comprises a user interface, a controller having a memory unit to store an inventory of ingredients operatively linked to a user interface and programmed to control the serving dispenser. The controller is configured to dispense the customized dietary supplement based on a user input. The vending machine prevents user from having unhealthy snacks for dialysis. The method decreases health complication faced by the dialysis patients. The vending machine provides wide product selection and optimal component storage capacities. It also affords improved product quality, which helps in improving the patients&#39; health.
PURPOSE:To provide safe orthodontic parts made of titanium having excellent mechanical characteristics. CONSTITUTION:The orthodontic parts made of the titanium are produced by a stage for obtaining a mixture by mixing titanium raw material powder and a binder, a stage for obtaining moldings by injection molding the mixture, a stage for removing the binder in the moldings and a stage for obtaining sintered compacts by sintering the moldings from which the binder is removed. The sintered compacts obtd. in such a manner have a compsn. contg. &lt;=0.25wt.% carbon and &lt;=0.6wt.% oxygen and the balance Ti with inevitable impurities and the relative density thereof is &gt;=97.0%.
The present invention is directed to methods of treating cells infected with HCV and mammals suffering from HCV infection by transfecting the infected cells with miRNA-196 mimic. miRNA-196 mimic significantly down-regulates Bach1 protein and HCV gene expression, while also up-regulating HMOX1 gene expression. miRNA-196 binds with the 3&#39;-UTR of Bach1 mRNA to reduce the expression of Bach1. As such, miRNA-196 can play an important role in the regulation of HCV  replication and HMOX1/Bach1 expression in hepatocytes. The present invention also provides a formulation for the treatment of cells expressing HCV comprising a therapeutically effective amount of miRNA-196 such that Bach1 and HCV gene expression are down- regulated while HMOX1 expression is increased. The formulations are adapted to enable the transfection of miRNA-196 mimic into hepatocytes expressing HCV proteins.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide formulations for storing rAAV (recombinant adeno-associated virus) virions.  &lt;P&gt;SOLUTION: There are described a stable pharmaceutical compositions comprising the rAAV virions. The compositions provide protection against loss of rAAV vector genomes and transduceability under conditions such as exposure to cycles of freezing and thawing and storage in glass and polypropylene vials. The compositions comprise the rAAV virions in combination with one or more dihydric alcohols or polyhydric alcohols, and, optionally, a surfactant such as a sorbitan ester. There are also described methods for using the compositions.  &lt;P&gt;COPYRIGHT: (C)2011,JPO&amp;INPIT
The present invention relates to the synthesis and descriptive of a series of peptides and their derivatives that have structures whose formula is detailed below and whose pharmacological function is to present analgesic properties in the human body similar to those of morphine. These peptides, whose sequence and synthesis are described for the first time, are chemically related to the &#34;enkephalins&#34;. The discovery and isolation of plasma from vertebrate mammals of substances of peptide nature and analgesic action similar to that of morphine and other typical opiates has opened a new field in the study of pain and biochemical mechanisms that in their transmission and perception intervenes. The peptides isolated from the brain were called enkephalins, and from the study of their analgesic action it is evident that due to their peptide nature they are susceptible to being hydrolyzed by the cerebral enzymes, which is why, although they are as active as morphine, the duration of the effect produced is extremely short. A series of peptides of enkephalin-like sequences have been synthesized, presenting slight structural modifications with respect to them; the results obtained from pharmacological tests indicate a remarkable opiate activity that makes them suitable for a possible pharmacological use. (Machine-translation by Google Translate, not legally binding)
Adenoviral vectors with a deletion of the E3 region such that the remaining E3 region reduces the TNF response of a host mammalian cell infected with the virus. The portion of the E3 region remaining in these vectors encodes the 14.7 kD protein, and may also contain a deletion of at least the E1a promoter. These partially deleted E3 vectors will inhibit the host cell&#39;s immune response so that the infected cell will live longer. Any non-adenoviral gene expressed from these vectors in the infected cell will be produced for a longer length of time and achieve a higher concentration than when adenoviral vectors not expressing function 14.7 kD protein are used. These 14.7 kD expressing adenoviral vectors will be useful for gene therapy and especially in cancer gene therapy where the non-adenoviral DNA sequence being expressed are preferably cytokine genes, such as IL-1, and suicide genes, such as HSV-tk. The vectors also are useful for antisense therapy.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a means for reducing transient irritation in a preparation of ascorbic acids in high concentration.  &lt;P&gt;SOLUTION: The external preparation for the skin contains (1) 4-6 wt.% one or more kinds selected from ascorbic acid, a derivative thereof and a salt thereof, and (2) 0.4-1 wt.% buffer. Phosphoric acid and a salt thereof are used as the buffer, and the pH is regulated so as to be 8-9. An essence of a plant of Tiliaceae such as Tilia europaea, a plant of Asteraceae such as Calendula officinalis and Arctium Lappa, or a plant of Rosaceae such as Sanguisorba officinalis can be contained as an antiinflammatory component. An essence of a plant of Betulaceae such as Betula japonica x, or an essence of a plant of Moraceae such as Morus bombycis Koidz is suitably contained as other galenical essences.  &lt;P&gt;COPYRIGHT: (C)2004,JPO&amp;NCIPI
A computing system may identify a surgical instrument for a surgical procedure in an operating room (OR). The computing system may detect a control input by a health care professional (HCP) to control the surgical instrument. The computing system may determine the HCP&#39;s access control level associated with the surgical instrument. The computing system may determine whether the HCP has an authorization to control the surgical instrument. If the computing system determines that HCP is unauthorized to control the surgical instrument based on the access control level associated with the HCP, the computing system may block the control input by the HCP. If the computing system determines that the HCP is authorized to control the surgical instrument based on the access control level associated with the HCP, the computing system may effectuate the control input by the HCP to control the surgical instrument.