anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
PROBLEM TO BE SOLVED: To produce amorphous and nonporous silica fine particles which are easy to handle and which are obtd. from an easily available source material by reacting sodium silicate with a gelling agent in a wet state to obtain a silica hydrogel and subjecting the obtd. silica hydrogel to successively ageing, neutralizing, cleaning with water and drying. SOLUTION: Sodium silicate is reacted with a gelling agent in a wet state to obtain a silica hydrogel, which is treated in specified processes to obtain silica fine particles having the following properties. The obtd. particles have 0.2 to 100 μm average particle size, &lt;=0.22 cc/g pore volume, &lt;=200 m&lt;2&gt; /g specific surface area, 20 to 50 ml/100 g oil absorption by the method according to JIS-K5101, &lt;=1% moisture absorptivity at 20% relative humidity, &lt;=2% moisture absorptivity at 2% moisture absorptivity at 50% RH, and &lt;=5% moisture absorptivity at 90% RH, at 25 deg.C according to a JIS-Z070 method, and the particles are amorphous in the X-ray diffraction analysis and do not substantially have crystalline peaks. In the IR absorption analysis, absorption peaks of isolated silanol groups are substantially present by IR absorption analysis.  The particles of which dissolving amt. is 60 to 200 mg/l in a cell analogue liquid at 20 deg.C, are obtained.
The oxalic acid-bis-hydroxy arylamide of the formula &lt;FORM:0987798/C2/1&gt; is prepared by the reaction of 1-amino-2- hydroxy-5-tertiarybutyl benzene with oxalic acid dichloride.ALSO:Polyacrylonitrile, polyvinyl chloride, polyvinyl acetate, poly-a -olefins, polyamides, polyesters, epoxy resins, polystyrene, alkyd resins, resins produced by the reaction of formaldehyde with phenol, urea or melamine, rubber, balata, guttapercha, polychloroprene, olefinic polysulphides and polybutadiene are protected against ultra-violet light by incorporating therein an oxalic acid-bis-hydroxyarylamide having the formula &lt;FORM:0987798/C3/1&gt; in which A is a benzene residue. Compounds having the formula &lt;FORM:0987798/C3/2&gt; in which X is a hydrogen or chlorine atom, an alkyl radical with 1-12 carbon atoms, a methoxy group or a phenyl or cyclohexyl group are preferably used. The compound may be incorporated into synthetic polymers before, during or after polymerization.  The treated materials may be used for the production of fibres or films, for treating textiles or as lacquers. 0.01-10% by weight of the compound may be incorporated.ALSO:Halic acid-bis-hydroxyarylamides having the formula &lt;FORM:0987798/C4-C5/1&gt; in which A is a benzene residue are incorporated into oils, fats, waxes, candles, polishes and soaps to protect them against ultraviolet light. Compounds having the formula &lt;FORM:0987798/C4-C5/2&gt; in which X is a hydrogen or chlorine atom, an alkyl radical with 1-12 carbon atoms, a methoxy group or a phenyl or cyclohexyl group are preferably used.  0.01-10% by weight of the compounds may be incorporated.ALSO:Oxalic acid-bis hydroxy aryamides having the formula &lt;FORM:0987798/A5-A6/1&gt; in which A is a benzene residue are incorporated into perfumes, bath salts, skin and face creams, powders, insect repellants and sunburn oils and creams to protect them against ultraviolet light. Compounds having the formula &lt;FORM:0987798/A5-A6/2&gt; in which X is a hydrogen or chlorine atom, an alkyl radical with 1-12 carbon atoms, a methoxy group or a phenyl or cyclohexyl group are preferably used.  0,01-10% by weight of the compounds may be used.ALSO:Textile materials, e.g. wool, silk, cotton, hemp, flax, linen, jute, ramie, regenerated cellulose, acetate rayon, cellulose triacetated polyacrylonitrile, polyvinyl chloride, poly-a -olefin, polyamide or polyester fibres, feathers, straw, wood, wood pulp, paper, cardboard or chip board are protected against ultra-violet light by applying thereto an oxalic acid-bis hydroxyacrylamide having the formula &lt;FORM:0987798/D1-D2/1&gt; in which A is a benzene residue.  Compounds having the formula &lt;FORM:0987798/D1-D2/2&gt; in which X is a hydrogen or chlorine atom, an alkyl radical with 1-12 carbon atoms, a methoxy group or a phenyl or cyclohexyl group are preferably used.  The compound may be applied together with starch, casein, polyvinyl acetate or polymeric derivatives of acrylic acid.  0. 01-10% by weight of the compound may be applied.
PROBLEM TO BE SOLVED: To obtain a therapeutic agent and a preventive for shock disease, by using a theophylline derivative. SOLUTION: A preparation having antishock action is obtained by using a theophyline derivative containing at least one ether function at a structurally modified methyl group at the 1-position. The compound having the substitution type is a new xanthin compound of formula I (R&lt;1&gt; is a 1-5C alkyl, phenyl, etc.; A is a 1-4C alkylene cross-linking; R&lt;2&gt; is a 1-5C alkyl, a 3-6C cycloalkyl, etc.). The compound of formula I is obtained by reacting a 3-substituted xanthin of formula II with a reagent of the formula R&lt;a&gt; -X (R&lt;a&gt; is benzyl, benzhydryl, etc.; X is Cl, Br, sulfonic acid ester, etc.) to give a 1,3,7-trisubstituted xanthin of formula III and removing R&lt;a&gt; . The compound if effective for treating and preventing systemic inflammatory reaction syndrome, septic shock, multiple organ insufficiency, acute dyspnea syndrome, hemorrhagic and traumatic shock.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an aqueous wax dispersion fine in particle size, excellent in pH tolerance, salt tolerance and stability, easy to prepare, and flat in emulsified particle stability regardless of ingredients, and a cosmetic with flexibility without spoiling hardness, a wax formulation, and a solid wax composition.  &lt;P&gt;SOLUTION: A polyoxyethylene sorbitol fatty acid ester is obtained by reacting a polyoxyethylene sorbitol prepared by adding an average of 20-100 moles of ethylene oxide to one mole of sorbitol with a 20-40C saturated fatty acid by a mole ratio of 1:2.5-1:5.5 to esterify to an acid value of not greater than 10 mgKOH/g. The cosmetic, and a wax dispersing agent for an aqueous system include the ester. The solid wax composition includes the ester, and a wax. The aqueous wax dispersion includes the ester, the wax, and water, and has a wax content of 0.1-60 mass%, and an ester content of 0.01 pts.mass or more to one pts.mass of the wax. The cosmetics, and the wax formulation includes the dispersion.  &lt;P&gt;COPYRIGHT: (C)2008,JPO&amp;INPIT
A smart patch includes a computing device to monitor user health metrics. The smart patch also includes an adhesive coupled to a cradle with an opening and coupled to at least two electrodes capable of electrically coupling to the user. The computing device contains one or more sensors, a battery and a sensor window. The sensors are configured to interface with the user to generate physiological data associated with the user&#39;s health. The battery is configured to power the sensors. The computing device is removably coupled to the cradle. The cradle is configured to engage the computing device securing the computing device to the adhesive. The electrodes electrically couple to the user&#39;s skin and conduct electrical signals between the user and the computing device.
FIELD: fodder production, animal science. SUBSTANCE: the suggested growth-stimulating fodder supplement includes the mixture of plant raw material which contains biologically active penta- and tetracyclic alcohols (phytosterols) and soluble sugar. It was subjected to mechanochemical activation at the following ratio of components, weight%: plant raw material 60.0-90.0, soluble sugar 10.0-40.0. Growth-stimulating supplement predominantly contains sea buckthorn leaves or millet groats&#39; waste products as plant raw material. EFFECT: increased mean daily body weight gains in youngsters and strengthened immune system by excluding completely the mortality due to biologically acceptable, useful biologically active substances which include triterpenoid and phytosterols, higher ecological purity. 2 cl, 4 tbl
A method and composition for the inhibition of growth of Salmonella is provided. The effective composition of the invention is a composition which is fermented by microflora other than Salmonella at a rate competitively greater Salmonella or which is fermented by microflora other than Salmonella to produce metabolites which inhibit the growth of Salmonella. In one embodiment of the prevent invention, the effective composition is a class of fructo-oligosaccharides which inhibit the growth of Salmonella. More particularly, the fructo-oligosaccharides are sucrose molecules having from 1 to 8 fructose residues. This class of sugars is exemplified by &#34;Neosugar&#34; which includes 1-kestose, nystose, and 1-fructofuranosyl-nystose. The present method includes containing Salmonella with the effective composition and can include feeding it to a domestic food animal. The present composition includes the effective component and nutritive feed material.
A dental device is disclosed for applying medicine to a patient&#39;s teeth. The device includes a handle having a distal end and a proximal end. The handle has a handle lumen extending from the distal end towards the proximal end. The handle also has a suction exit port that is fluidly connected to the handle lumen. A fork is connected to the handle at the distal end. The fork includes a fork base with at least two prongs, wherein each prong has a suction port that is fluidly connected to the handle lumen through a prong lumen. Floss is strung across the two prongs.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an incense stick bundle with an ignition agent, efficiently and surely ignited and uniformly igniting the front end incense stick group by devising attaching specifications of the ignition agent to be attached on the front end side of the incense stick bundle.  &lt;P&gt;SOLUTION: The ignition agent is attached on one end surface of the incense stick bundle to enfold the corner part near the periphery of the end surface except at least the midsection. The attaching specifications may indicate a formation that the ignition agent is continuously linked around to integrate with the incense stick front end of one side, or a formation that the ignition agent is discontinuously linked around without attaching on a part of peripheral edge part. Wherein, the ignition agent is attached after impregnating or coating an oxidant near one end side including the front end surface previously. The ignition agent may be not only set on the peripheral edge part but also further attached on the midsection of one end surface. In the case, the thickness on the midsection is made thiner than that on the peripheral edge part. When being attached on the peripheral edge part and the midsection, it is preferable to form small pores or cracks aerating to the inside or the outside of the incense stick bundle.  &lt;P&gt;COPYRIGHT: (C)2009,JPO&amp;INPIT
The alpha subunits of hemoglobin, which in nature are formed as separate polypeptide chains which bind noncovalently to the beta subunits, are here provided in the form of the novel molecule di-alpha globin, a single polypeptide chain defined by connecting the two alpha subunits either directly via peptide bond or indirectly by a flexible amino acid or peptide linker. Di-alpha globin may be combined in vivo or in vitro with beta globin and heme to form hemoglobin. Di-alpha globin is expressed by recombinant DNA techniques. Di-beta globin may be similarly obtained. We further describe the production of tetrameric human hemoglobin and di-alpha/beta2 hemoglobin in the yeast Saccharomyces cerevisiae. The synthesis of the protein is directed by a synthetic promotor consisting of two functional parts, an upstream activator sequence (UAS) that confers inducible transcription by galactose from a consensus yeast transcriptional initiation site. The expression construct is designed such that translation is expected to initiate at the same position as the human wild-type genes for  alpha - and  beta -globin. Three different types of expression vectors have been used: (1)  alpha -globin and  beta -globin contained on two separate plasmids (pGS4688 and pGS4988) in a diploid yeast strain; (2)  alpha -globin and  beta -globin each contained on a single plasmid (pGS289 and pGS389) and expressed in either haploid or diploid strains; and (3) di-alpha-globin and beta globin contained on a single plasmid (pGS 3089)and expressed in haploid strains. Finally, we describe the co-expression of alpha and beta globin chains. The chains are folded together and combined intracellularly with heme to form active tetrameric hemoglobin. The hemoglobin may be recovered from the cells&#39; soluble fraction. The invention thus obviates the need to express alpha and beta globin separately, solubilize, renature and purify them, and combine them in vitro with heme to obtain an artificial hemoglobin. By way of comparison, the separately expressed beta globin known in the art is deposited in inclusion bodies. Polycistronic co-expression of alpha and beta globins is particularly preferred.
The present invention relates to a novel tobacco health-care cigarette which belongs to the fields that smoking is favorable for health and smoking plays a role in treating diseases. The novel tobacco health-care cigarette solves the difficulty of the harm of smoking. Raw materials, and the natures, the flavors and the functions thereof are as follows: 1. green tea is bitter, sweet and cool, and has the functions of clearing away heat and toxin, refreshing the mind, etc.; 2. jasmine flower is sweet, pungent and warm, and has the functions of regulating Qi, expelling stagnation, tranquilizing, repelling foulness and harmonizing the middle warmer; 3. coastal glehnia root is sweet, a bit bitter and a bit cold, and has the functions of nourishing Yin and clearing the lung, benefiting the stomach for promoting the production of body fluid, expelling phlegm and arresting cough; 4. American ginseng root is bitter, a bit sweet and cold, and has the functions of invigorating Qi, nourishing Yin, and clearing away the fire for promoting the production of body fluid. Note: details refer to &#39;the specification and the prove information abstract&#39; please.
&lt;P&gt;PROBLEM TO BE SOLVED: To obtain an endoplasmic reticulum protein having a disulfide bond reduction activity and to provide a method for decomposing and/or removing a misfolded protein in cells by the protein.  &lt;P&gt;SOLUTION: Protein ERdj5 having disulfide activity is purified. The endoplasmic reticulum protein exhibits reduction activity. The gene is directly expressed in cells to directly exhibit the decomposition promotion activity of the misfolded protein. Namely, a known endoplasmic reticulum protein ERdj5 has reduction power differently from the conventionally reported result and is elucidated to promote the decomposition of protein misfolded in the cells.  &lt;P&gt;COPYRIGHT: (C)2008,JPO&amp;INPIT
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a functional food capable of decreasing a blood glucose level without causing side effects, and to provide a medicament.  &lt;P&gt;SOLUTION: Brassica campestris (Komatsuna) or its hybrid is used in decreasing blood glucose as the functional food or the medicament, because it decreases the blood glucose level or inhibits increase of the blood glucose level. A juice, a jelly or a dried pulverized powder is exemplified as the functional food. The juice is produced by pulverizing and mixing the Komatsuna or its hybrid together with a liquid and a bitterness softening material. The powder is produced by subjecting the Komatsuna or its hybrid to drying, such as solar drying, vacuum drying, and freeze-drying, and then to pulverizing. The Komatsuna or its hybrid is effectively decreased in its bitterness, by preliminarily treating it with hot water, etc., and then processing it to remove elements causing the bitterness.  &lt;P&gt;COPYRIGHT: (C)2004,JPO
PURPOSE:To obtain the title material causing little color change by polymerization and having excellent beautifulness and mechanical strength, by using a polymerizable monomer, a polymerization initiator and a powder filler as main components, wherein the filler exceeding a specific average particle diameter is composed of two or more components having a specific refractive index. CONSTITUTION:The objective material contains a polymerizable monomer [preferably (meth)acrylic acid esters or urethane (meth)acrylates], a polymerization initiator (e.g. a peroxide and a promoter) and a powdery filling material (e.g. glass powder) as main components, wherein said filling material is composed of the component having an average particle diameter of &gt;=0.1mum as a filler and the other components as a matrix and contains at least one kind of filler satisfying the relationship of formula I and a filler satisfying the formula II. In the formulas, nm and np are refractive indices of the matrix before polymerization and after polymerization, respectively and nf is refractive index of the filler. The compounding ratio of the fillers having different refractive indices is preferably 15-85wt.% to 85-15wt.%.
A novel thermoplastic elastomer (TPE) which comprises (i) polymeric A blocks in which there are side chains comprising crystallizable moieties having a melting point Tq, and (ii) at least one amorphous polymeric B block having a glass transition point, Tgs, which is less than (Tq - 10)°C. The relative proportions and molecular weights of the A and B blocks can be adjusted so as to produce desired physical properties with comparatively little change in Tq, which depends chiefly upon the nature of the crystallizable moieties, which may be for example n-alkyl groups containing 12 to 50 carbon atoms. The novel TPE&#39;s show a sharply reduced viscosity in the region of Tq, and can be melt-processed at temperatures close to Tq. The novel TPE&#39;s are useful in the form of compositions, shaped articles and assemblies which comprise one of the novel TPE&#39;s and a second component which is mixed with, or surrounded by, or surrounds or otherwise provides a substrate for, the TPE. Preferred second components are explosives and other energetic materials, pharmaceuticals, seeds, perfumes, deodorizers, pest control agents, herbicides, insecticides, fungicides, biologically active materials, agrichemicals, and disinfectants. Second components can be released from such a composition or shaped article by a natural increase in the ambient temperature or by heating the composition or article to a temperature at least equal to Tq by means of heat which is (i) generated artificially or (ii) generated by a mammalian body and/or (iii) is conveyed artificially to the composition, article or assembly.
&lt;P&gt;PROBLEM TO BE SOLVED: To obtain a humectant that is highly safe to the human body and has excellent effects, and to provide a skin care preparation for external use containing the humectant.  &lt;P&gt;SOLUTION: The humectant comprises an acidic xylooligosaccharide as an active ingredient. The acidic xylooligosaccharide is a mixed composition of xylooligosaccharides having different polymerization degrees of xylose and has ≥2 and ≤5 average polymerization degrees. The xylooligosaccharide composition is readily obtained by enzymically and/or physicochemically treating a lignocellulose material to give a complex of a xylooligosaccharide component and a lignin component and then hydrolyzing the complex with an acid. The humectant is formulated with a skin care preparation for external use and used.  &lt;P&gt;COPYRIGHT: (C)2005,JPO&amp;NCIPI
The present invention pertains to the field of medicine and may be used for producing a specific antiserum as well as for carrying out immunological diagnoses of malignant tumours. This method for producing an antiserum involves sampling an embryo at the foetal stage from animals of a same genetic type so as to obtain a cell suspension. After immunization, spleen cells from the animal are sampled, lymphocytes are separated and an animal of the same genetic line is immunized with the lymphocyte suspension. Cells originating from healthy organs of the same animals are added to the obtained antiserum. The serum is then purified away from the sediments. In order to carry out a diagnosis, the filtrate is added to the subject&#39;s blood and the results are obtained by an immunodetection method. It is thus possible to diagnose a tumour when the test values obtained differ from reference values.
PURPOSE:To purify glutathione of high purity in high recovery ratio by simple operation, by passing a crude solution of glutathione containing impurities through a strongly acidic cation exchange resin, adsorbing the glutathione and impurities therein, and eluting the adsorbed glutathione with an alkali hydroxide. CONSTITUTION:A crude solution of glutathione, e.g. a yeast cell extract, containing impurities, e.g. amino acids, peptides or proteins, is passed through a column packed with a strongly acidic cation exchange resin (H&lt;+&gt; type) to adsorb the glutathione and impurities therein. The resin is then washed with water, and a 0.05-0.5N alkali hydroxide is then made to flow through the column to obtain a fraction for each 10ml. The amount of the glutathione in the respective fractions is analyzed by the alloxan method. A fraction, eluted after the initial fraction containing no glutathione, and containing glutathione of high purity is recovered to purify the glutathione.
A method and system are provided for consolidating and distributing information. Implementation of system functionalities for both restricted local and unrestricted system-wide uses are permitted. Open standards for hardware, software and firmware components and standardized medical codes, definitions and formats are supported. The preferred embodiment of the invention provides an integrated health care system. The invention can also be used to allow secure access to Social Security, annuity, retirement account, and benefit information, allowing individuals a unified view of their benefit and payment status. A centralized host maintains, consolidates, and redistributes information generated at all networked locations. Information is electronically transferred among the system components to link an individual&#39;s local records to those stored remotely. The individual information device, centralized host computer, and any other computers or networks linked to the system can therefore be automatically updated. An individual information device stores a service recipient&#39;s insurance information, a emergency records and critical health care histories. This information is accessed by the system for use in managing any aspect of the service recipient&#39;s health care. Portable terminals can be used to access the system. A portable terminal can also be used independently from the system to perform health care functions. Unrestricted system-wide, or restricted local uses are supported. Insurance coverage for services and treatments can be determined and the information transmitted directly from the carrier(s) to the service recipient and service provider(s). Supported features include service authorization, messaging, diagnostic services, coverage determination, billing, and electronic payment.