anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
&lt;P&gt;PROBLEM TO BE SOLVED: To improve the stability over time of a gel-formed cosmetic containing 2-aminoethane sulfinic acid and dimethylsilanol hyaluronate, also secure continuous stability on the antioxidative property of removing active oxygen and further secure coloring stability.  &lt;P&gt;SOLUTION: This cosmetic is provided by containing the 2-aminoethane sulfinic acid, dimethylsilanol hyaluronate and Lithospermum erythrorhizon as essential components. Also, the gel-formed cosmetic is provided by adding pycnogenol, glucosylhesperidin, water-soluble collagen, the oil-soluble extract of radix Glycyrrhizae uralensis and the hydrolyzate of elastin, further adding coenzyme Q10 and fish-originated collagen and further more the hydrolyzate of soybean protein and succinic acid. The gel-formed cosmetic is further obtained by adding cholesteric liquid crystal. Thereby, the stability over time of its quality is improved and the lasting stability on the antioxidative property of removing the active oxygen is also secured.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
This invention relates to the field of biological medicine preoaration including using the administration by gavage of B mouse trough the abstract of the water of common anemarrhena rhizome to discover the expressiom of specific restraining uncoupling protein 2(UCP2), so to treat the insulin resistance. Use water to decoct common anemarrhena rhizome, condense the decocted common anemarrhena rhizome water by using rotating vaporator, reduce vaportator&#39;s pressure and dry the condensed liquid in cold so to gain the condensed crystal abstracts. Use the abstracts to prepare a given thickness water solution. Perfuse the solution into the rat&#39;s stomach, it can obviously show that this solution can restrain the UCP2 in the rat&#39;s kidney. This invention has clarifie that the extracted liueid of common anemarrhena rhizome can specificly restrain UCP2 in the kidney. It can be developed into medicine that can improve and treat insulin resistance.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a sustained release ointment having character suitable for administration using a syringe, instantaneously solidifiable upon contacting with water after administered, and also stably compoundable with an unstable biologically active medicament such as a tetracycline-based antibiotic, to provide a method for producing the ointment, and to provide a kit for treating periodontal diseases enabling the ointment to easily be administered into periodontal pockets using a syringe.  &lt;P&gt;SOLUTION: The sustained release ointment of local administration type comprises a biodegradable polymer, a polyethylene glycol and a biologically active medicament. This ointment has such a property as to be instantaneously solidified upon contacting with water. The method for producing the ointment comprises the steps of heating both the biodegradable polymer and the polyethylene glycol to 70-120°C to effect liquefaction and homogeneously mixing them together. The kit for treating periodontal diseases is obtained by encapsulating the ointment into a syringe for administering it into periodontal pockets.  &lt;P&gt;COPYRIGHT: (C)2003,JPO
PURPOSE: To obtain the highly stable, quickly soluble preparation servable for medical use through dissolving itself in water when to be taken, consisting of granules produced by agitating granulation of sodium alginate powder with a lower alcohol. CONSTITUTION: This solid preparation soluble in water within 3 minutes is obtained by charging a crushing blade-free agitating granulator with sodium alginate followed by adding an aqueous lower alcohol solution to the compound followed by conducting an agitating granulation. The lower alcohol is pref. methanol, ethanol, l-propanol or 2-propanol. The alcohol concentration of the aqueous solution is pref. 10-50 (esp. 20-30)wt.%. The granular diameter of this preparation is pref. &lt;=700μm with the granules &lt;=250μm in diameter accounting for &lt;15wt.% of the total granules. If desired, a binder (e.g. sodium alginate, starch, dextrin) may be used in this solid preparation.
FIELD: medicine. ^ SUBSTANCE: group of inventions relates to field of veterinary medicine. Combined vaccine against dog&#39;s leptospirosis contains preparation of Leptospira cells from Leptospira bratislava, Leptospira canicola, Leptospira grippotyphosa, Leptospira icterohaemorrhagiae and Leptospira pomona and a carrier. Quantity of each Leptospira strain in combined vaccine is in the range of nearly 100-3500 nephelometric units per a dose of vaccine. Combined vaccine for immunisation of dogs against dogs&#39; pathogens additionally contains attenuated strain Snyder Hill of dogs plague virus (CD), attenuated strain Manhattan of adenovirus of dogs of 2 type (CAV-2), attenuated strain of virus NL-CPI-5 of dogs parainfluenza (CPI), attenuated strain NL-35-D of dogs&#39; parvovirus (CPV) and carrier, where said virus CD, CAV-2, virus CPI and CPV are in the range from ot 102 to 109 TCID50 (inflectional dose with 50% cytopathic effect in tissue culture) per a dose. Method of dog&#39;s protection against leptospirosis and other pathogens includes introduction to a dog of said above combined vaccines in therapeutically effective quantity. ^ EFFECT: vaccines and method have high efficiency, are harmless. ^ 15 cl, 4 dwg, 49 tbl, 6 ex
PURPOSE:To obtain the subject medicine, having both strong immunopotentiating and proliferation inhibiting actions on a cancerous cell together, composed of a hot water extract from a rhizome of Polygonum sachalinense Fr. Schm. and useful as a potentiating substance for anticancer actions without deteriorating the activity by the enzymic hydrolysis even in oral administration. CONSTITUTION:This immunopotentiator comprises a hot water extract separated from a rhizome of Polgonum sachalinense Fr. Schm. or a precipitated substance of the hot water extract with a 80% ethanol as an active ingredient. The extract is obtained by crushing, e.g. the rhizome of the Polygonum sachalinense Fr. Schm., extracting the crushed rhizome with hot water at &gt;=80 deg.C for 30min, then filtering, concentrating and freeze-drying the prepared extract solution.
PURPOSE:To store livestock semen keeping the activity of the semen for a long time with little damage of the semen, with a simple refrigeration process, by contacting the livestock semen with Ringer&#39;s solution containing albumin or activated charcoal interposing a dialysis membrane therebetween. CONSTITUTION:For example, livestock semen 8 is placed ina dialysis membrane tube 2 and sealed with a cap 5. At the same time, the space between the dialysis membrane tube 2 and the vessel 1 is filled with Ringer&#39;s solution containing albumin or activated charcoal, and sealed. That is to say, the semen for the artificial conception of livestock, esp. pig, is stored in contact with the Ringer&#39;s solution interposing a dialysis membrane therebetween. The storage temperature is pref. about 15 deg.C. The harmful substance formed in the semen at about 15 deg.C can be removed by albumin or activated charcoal through the dialysis membrane, and the semen can be effectively stored. A commercial dialysis membrane for artificial kidney or a porous film can be used as the dialysis membrane.
PURPOSE:To obtain a water-based extract containing little precipitate and useful as pharmaceuticals and cosmetics, by extracting OUBAKU (bark of Phellodendron amurense) with a fatty acid ester to obtain a soluble component useful as an external drug for skin, and extracting the residue with a mixture of water and alcohol after defatting. CONSTITUTION:1pt. of OUBAKU is added to 2pts. of a fatty acid ester having a boiling point of &gt;=80-100 deg.C, immersed at 80-100 deg.C, and separated into the layer of the fatty acid ester (A-layer) and the residue (B-layer). The A-layer is left at rest at -20+ or -5 deg.C, and filtered to obtain a liquid containing the component soluble in the fatty acid ester (A-liquid). Separately, the B-layer is defatted with n- hexane, and extracted with a 1:1 mixture of water and propylene glycol (or ethanol, etc.) at 60-100 deg.C. The obtained liquid layer is left at rest at -20+ or -5 deg.C, and filtered to obtain a water-soluble extract (B-liquid) having little flocculate and precipitate. The extract has moisturizing effect to the skin, and can be used as an external drug for skin.
The present invention particularly relates to a method for heating gold nanoclusters. According to the present invention, the gold nanoclusters are subjected to electromagnetic induction heating by adopting an alternating magnetic field. When the gold nanoclusters 5 are in the alternating magnetic field, the internal magnetic flux changes, so that an induced, current is generatedJ As the gold nanoclusters are a metal material in nature and, has a certain resistivity, the induced current can generate heat (Joule&#39;s law) when. passing through the gold, nanoclusters, so that a heating lO effect is achieved. In addition, a heating mode provided by the present invention is mild and will not lead to high—temperature injury, and the gold nanoclusters can be kept stable when heated to a certain temperature, so that a technical foundation is laid for application of the gold nanoclusters to hyperthermia. The 15 method has a good application prospect. (+ Fig. l)
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a new treating agent effective for rheumatoid arthritis.  &lt;P&gt;SOLUTION: This treating agent of the rheumatoid arthritis is provided by using a substance having inhibitory activity against the activity of a protein kinase of which expression is increased in the cells of an animal suffering from the rheumatoid arthritis as compared with that in the cells of the animal not suffering from the rheumatoid arthritis, as an active ingredient. The protein kinase is preferably 1 or ≥2 protein kinases selected from the group consisting of tyrosine kinase and serine/threonine kinases. &#34;The protein kinase of which expression is increased in the cells of the animal suffering from the rheumatoid arthritis as compared with that of the cells of the animal not suffering from the rheumatoid arthritis&#34; is preferably selected from the group consisting of HCK, MET and RON. As the active ingredient, concretely, an inhibitor of Src family, a neutralizing antibody against the protein kinase or an inhibitor of MET are exemplified.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
Decades of investigations were focused on finding “gold standard” for evaluation of plasma dilution and osmolality, blood loss evaluation and prediction of bleeding or transfusion induced changes in hematocrit and hemoglobin concentration. Addressing deficiencies of existing methods, the current invention created new combined mathematical-physiological model applicable to manually operated nomograms and software in medical monitors. The mathematical model HBS Trends is used in blood transfusion and infusion therapy nomogram—HBS Nomogram—which is based on blood hemoglobin concentration and hematocrit. It is also an easy and practical tool for recording and dynamical interpretation of plasma osmolality, blood hemoglobin concentration, hematocrit and mean corpuscular hemoglobin concentration. The HBS Nomogram is a practical system for organizing blood test results in a patient&#39;s medical records. It can be used alone or, in line with existing guidelines for infusion and transfusion therapy making them more practical, cost effective and time saving in decision making.
PURPOSE: To obtain a pigment for a coating material, etc., by coating a synthetic mica having a smooth particle surface and an iron content equal to or lower than a specific value with a metal oxide, showing no yellow at a mass tone angle and a shade part, causing no faded color of an interference color. CONSTITUTION: A synthetic mica (e.g. tetrasilicon fluoride mica, etc.) containing Ti, Zn, Na, B, Li, Ca, Ge, Sr, Zr, etc., having &lt;=1.58 average refractive index and &lt;=1.0% iron content is mixed with water while stirring, blended with a solution of titanyl sulfate, rapidly heated to 100 deg.C, reacted at the temperature for 3 hours, filtered, washed with water and dried at 110 deg.C to give powder,, which is baked at 800 deg.C for 1 hour to give the objective pigment for a coating material, etc., by coating a synthetic mica which comprises the synthetic mica coated with a metal oxide (e.g. titanium dioxide, etc.), shows no yellow at a mass tone angle and a shade part, has solved the problem of a faded color of an interference color and is useful as a coating composition, cosmetic, ink, plastics etc.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide preventives or remedies for septicemia caused by microbial infection.  &lt;P&gt;SOLUTION: The preventive or remedy (1) for septicemia caused by microbial infection contains a soybean extract or a soybean fermentate as the active ingredient. The preventive or remedy (2) for septicemia caused by microbial infection contains isoflavone as the active ingredient. A food or drink, a drug, or a cosmetic (3) contains the preventive or the remedy as cited in (1) or (2). The preventives or remedies have high activity in inhibiting the abnormal production of TNF-α and are therefore useful in the fields of cosmetics and foods. They are useful for especially a patient with invasive deep mycosis, who is in a physical condition in which he or she is liable to be attacked by septicemia,.  &lt;P&gt;COPYRIGHT: (C)2005,JPO&amp;NCIPI
The monitoring device incorporates a memory device that is programmed with a set of question hierarchies. Each question hierarchy corresponds to a symptom and is composed of a set of questions. The question hierarchies may contain a logical structure so that certain questions will not be asked, depending upon a patient&#39;s answer to a preceeding question. A question hierarchy is invoked by a symptom identifier transmitted to the monitoring device by a remote computer. The remote computer may transmit a plurality of symptom identifiers to the monitoring device to cause the monitoring device to ask questions related to a plurality of symptoms. The set of symptoms inquired about may vary based upon the chronic disease afflicting the patient.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a treatment device, a treatment system and a method for controlling the treatment system, which enables to perform an advanced medical treatment to emergency patients in medical facilities where medical specialists are absent.  &lt;P&gt;SOLUTION: A first facility 61 where an emergency patient 51 and a medical assistant 52 are provided is provided with an image data acquisition part 1, a TV camera 4 and a treatment part 2. The image data of the emergency patient 51 obtained by the image data acquisition part 1 and the TV camera 4 is transmitted to a second facility 62 where a medical specialist (doctor 53) is provided through transmitting and receiving parts 11, 21 which communicates the medical information. After confirming that the preparation for treatment is completed based on the image data displayed on an image display part 23, the doctor 53 at the second facility 62 inputs a treatment performing signal into an input part of treatment performing signal 27. The treatment performing signal is transmitted to the receiving part 10 of treatment performing signal at the first facility 61 through the transmitting and receiving parts 11, 21 and the treatment by the treatment part 2 is instructed.  &lt;P&gt;COPYRIGHT: (C)2004,JPO
PURPOSE:To obtain water and oil repellent powder being excellent in water and oil repellency and being good in the touch after use, especially excellent in smoothness by treating a surface of a powder with hydrogenated lecithin or its Al salt, Mg salt, Ca salt, Zn salt, Zr salt, or Ti salt and a compd. contg. perfluoroalkyl group having a more carbon number than a specified carbon number. CONSTITUTION:The powder is surface treated with following chemicals a) and b) to obtain the water and oil repellent powder. Chemicals a) chemicals selected from a hydrogenated lecithin or its Al salt, Mg salt, Ca salt, Zn salt, Zr salt or Ti salt chemicals b): chamicals selected from a group of compd. (b-1)-(b-4), compd. (b-1): a epoxy compd. having a perfluoroalkyl group of a straight of branched &gt;=6C chain, compd. (b-2): a silane compd. having a perfluoroalkyl group of a straight or branched &gt;=6C chain, compd. (b-3) a titanium compd. having same condition as the above mentioned, compd. (b-4); a polysiloxane compd. having the same condition as the above mentioned.
PURPOSE:To produce titled glass adequate as a dental material without having defects such as cracks by subjecting a glassy casting formed by adding F atoms to the compsn of a ternary component system of CaO-Al2O3-P2O5 to multiple stages of crystallization treatments while heating up the casting. CONSTITUTION:F atoms are added to a raw material mixtue of the compsn. composed of 10-60wt% CaO, 5-35wt% Al2O3 and 25-85wt% P2O5 at &lt;=3pts. wt. by 100pts.wt. in total of the above-mentioned compsn. The mixture is melted and cast to produce the glassy casting. The glassy casting is subjected to &gt;=2 stages of the crystallization treatment while the temp. is gradually increased between the softening point thereof and the crystallization temp. of calcium phosphate. The melting of Al2O3 at the lower temp. is made possible by the incorporation of the F atoms into the compsn.; in addition, the cleaning up of the raw material is made easy and the time when the glass is kept melted is shorter; further the formation of crystal nuclei is accelerated in the crystallization stage of the glass. The titled glass having no voids and cracks is obtd. by multiple stages of the crystallization treatments.
PURPOSE:To obtain the title remedy by combining steroid with a trypsin inhibitor. CONSTITUTION:A remedy for autoimmune intestinal diseases is obtained by a combination of a steroid (a steroid with anti-inflammatory activity or its derivative) with a trypsin inhibtor such as urine-originating trypsin inhibtor or aprotinin. The preparation is effective against ulcerative colities, regional ileitis and intestinal Behchet&#39;s diseases. The steroid is used in the form of a water-soluble steroid (an organic acid salt with prednisolone), a lipid emulsion containing steroid, liposome containing steroid or a rectal preparation containing steroid. The administration is suitably effected orally or parenterally in combination once to several times a day. The dose is 0.1-10mg/day of the steroid and 1-100,000units/day of the trypsin inhibitor.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a technique uniformly dispersing a cationized polymer such as polyquaternium 37 which is liable to produce an aqueous component and pill ball into an aqueous carrier.  &lt;P&gt;SOLUTION: (1) Polyquaternium 37 and (2) dipropylene glycol are included in a cosmetic, preferably the cosmetic for hair, further preferably the cosmetic for hair fixing. The content of the polyquaternium 37 is preferably 0.05-1 pt. wt. and the content of the dipropylene glycol is preferably the same as that of the polyquaternium 37 or 40 times larger than that of the polyquaternium 37. In the cosmetic, the polyquaternium 37 is extremely favorably dispersed.  &lt;P&gt;COPYRIGHT: (C)2004,JPO
PURPOSE:To lyophilize a small amt. of sample securely and to prevent deterioration of the sample by freezing liquid contg. the sample to form semispherical drops on a cooling plate and drying the frozen drops under reduced pressure. CONSTITUTION:Liquid contg. a sample comprising solution or suspension, etc. is dropped onto a plate cooled by liquid N2, etc. to such low temp. as capable of freezing the liquid instantly to semispherical frozen product, and the frozen product is further dried under reduced pressure at &lt;=0 deg.C. Thus, a lyophilized product contg. desired agglutination activity units or desired units of weight, activity, or number of cell per dose, for red cell may be obtd. Further, since the product is lyophilized instantly due to its small surface area and dried without changing its shape, even easily deactivated samples such as virus can be lyophilized without deteriorating its activity with sufficient solubility preserved until it is renatured. Moreover, deterioration of the sample is held to the least degree since the sample does not directly contact a refrigerant at extremely low temp.
PURPOSE:To obtain the title remedy containing an antitryptase antibody capable of specifically reacting with tryptase as an active ingredient and having action strongly suppressing infection of human immunodeficiency virus. CONSTITUTION:The antibody obtained form serum obtained by immunizing tryptase, being a trypsin type new protease, isolated and purified form human lung mast cell, intraperitoneal mast cell, etc., of rat, consisting of tetramer having about 35000 subunit and having about 140000 molecular weight to an animal. The remedy containing the above-mentioned antibody or fragment containing antigen binding site thereof, e.g. F(ab&#39;)2 fragment obtained by pepsin treatment as an active ingredient. The dose of the antibody or the fragment is preferably 50-1000mg/kg weight/day as IgG fr fragment thereof. Vaccine for AIDS patient can be prepared using the above-mentioned tryptase alone or together with adjuvant.
A system allows transmittal of digital medical images of patients being transferred from a sending medical institution to a receiving medical institution. The system uses institutional account passwords, physician specific passwords, and a patient specific digital imaging data code (PSDIDC). Digital medical imaging data is uploaded to the system website server by the sending medical physician through HIPAA compliant firewalls and VPN in standard digital formats including but not limited the DICOM format. The PSDIDC is generated by the website server after the data upload is complete and available only to the sending institution and physician. The PSDIDC is unique and is never used again. Using out-of-band communication, such as telephonic communication, the sending physician provides the PSDIDC to the receiving physician while both physicians may be logged on to the service website with their on site computers and passwords. Both physicians can simultaneously view and discuss the images while logged on to the service website. The digital medical imaging data may be downloaded through a VPN into the receiving medical institution archival system by the receiving physician to be used at the receiving institution in whatever manner deemed necessary to meet the patient&#39;s and institution&#39;s needs. The downloaded digital medical imaging data may subsequently be viewed by the receiving physician in the same resolution as if data originally obtained at that institution.
PROBLEM TO BE SOLVED: To obtain the subject product which is free from faults such as hygroscopicity and stimulation, doesn&#39;t necessitate the application of high temperature and pressure in producing it and is applicable to all types of the skins without retaining fatty effect in spite of containing a large amount of oil by using a modified starch. SOLUTION: This product contains (A) a modified starch (suitably starch esterified with octenylsuccinic anhydride or the like) and (B) an oil phase containing an oil (e.g. liquid paraffin or the like) in proportions of 5-70 wt.% and 30-95 wt.% respectively, based on the whole weight of the composition. It is favorable that the objective product has a number-average particle size of 1-10 μm. The additive which is generally used in fields of cosmetics such as cosmetic or dermatological surfactants or emulsifiers and dermatology can be further added. This product is obtained by mixing the component B with an aqueous phase containing the component A to prepare an oil-in-water type disperser of 3:7 to 19:1 in the weight ratio between the component B and the component A followed by drying the disperser.