anthonyyazdaniml/gliner-biomed-balanced-curated-corpus huggingface dataset:
This invention pertains to the use of a degassed perfluorocarbon (&#34;PFC&#34;) liquid as a method of removing gas emboli from parts of a patient&#39;s internal anatomy. Moreover, the invention can be used as a method of imaging parts of a patient&#39;s internal anatomy. Furthermore, the invention can also be used as a way of delivering biological agents to parts of a patient&#39;s internal anatomy which contain or are surrounded by gas emboli and/or which are to be imaged. In this invention, a degassed PFC liquid is delivered to a region within the patient&#39;s internal anatomy which contains gas emboli and/or which is to be imaged. If gas emboli are present, the degassed liquid is permitted to absorb at least a portion of the emboli. Thereafter, the emboli-containing liquid is removed from the patient or is used as an imaging agent. If gas emboli are not present, the cite is imaged before the degassed liquid reaches atmospheric equilibrium. Thereafter, the liquid is removed from the patient. Moreover, by mixing a biological agent with the degassed PFC liquid, the mixture can be used as a way of topically treating parts within a patient&#39;s internal anatomy. Furthermore, by regulating the temperature of the degassed liquid, it can also be used as a way of hypo- or hyperthermically treating the patient.
Urine, or extracts therefrom, containing the follicle hormone is treated with reagents for ketonic compounds whereby precipitates of condensation products are obtained from which the follicle hormone may be split off, as by boiling with dilute acids or by double decomposition with aldehydes or ketones.  The reagents specified are hydroxylamine, hydrazines, semicarbazide, thiosemicarbazide, aminoguanidine and their substitution products.  According to examples: (1) a solution of semicarbazide in acetic acid is added to filtered urine, kieselguhr is added and the insoluble reaction product is filtered off, and boiled with alcoholic hydrochloric acid; the reaction mixture is extracted with ether, the ether evaporated and the residue purified by treatment with ethyl acetate and petrol ether and subsequent recrystallization from acetic acid or alcohol; (2) mares&#39; urine is concentrated and steam distilled and the residue dissolved in alcohol and boiled with hydroxylamine acetate; the reaction mixture is concentrated, then diluted with water and decanted from the precipitate of oximes, which is then split up by heating with alcoholic hydrochloric acid.  Specifications 391,686 and 392,434 are referred to. The Specification as open to inspection under Sect. 91 refers also to the treatment of hormone-containing extracts from placenta or other organs or from vegetable matter. This subject-matter does not appear in the Specification as accepted.ALSO:Urine, or extracts therefrom, containing the follicle hormone is treated with reagents for ketonic compounds whereby precipitates of condensation products are obtained from which the follicle hormone may be split off, as by boiling with dilute acids or by double decomposition with aldehydes or ketones.  The reagents specified are hydroxylamine, hydrazines, semicarbazide, thiosemicarbazide, aminoguanidine and their substitution products. According to examples: (1) a solution of semicarbazide in acetic acid is added to filtered urine, kieselguhr is added and the insoluble reaction product is filtered off, and boiled with alcoholic hydrochloric acid; the reaction mixture is extracted with ether, the ether evaporated and the residue purified by treatment with ethyl acetate and petrol ether and subsequent recrystallization from acetic acid or alcohol; (2) mares&#39; urine is concentrated and steam distilled and the residue dissolved in alcohol and boiled with hydroxylamine acetate; the reaction mixture is concentrated, then diluted with water and decanted from the precipitate of oximes, which is then split up by heating with alcoholic hydrochloric acid.  Specifications 391,686 and 392,434 are referred to.  The Specification as open to inspection under Sect. 91 refers also to the treatment of hormone-containing extracts from placenta or other organs of from vegetable matter.  This subject-matter does not appear in the Specification as accepted.
FIELD: biotechnology, medicine, gynecology. SUBSTANCE: strain is isolated from vagina of health woman of reproductive age and able to inhibit opportunistic microorganisms effectively both in vitro and in vivo. Strain produces acids and shows expressed adhesion to vaginal epitheliocytes. Strain Bifidobacterium breve P2 is deposited in TSMPM &#34;VNIIgenetics&#34; institute at N Ac-1579. Strain is nonpathogenic and apyretic for humans and animals, it normalizes microflora of genital tract in women. Strain is ready for using in obstetrics-gynecological practice as preparation-probiotic. Strain provides correction of dysbiotic disorders of vaginal microflora, inhibits the growth of opportunistic microorganism in vitro effectively. Invention can be used as preparation-probiotic for correction of microbiocenosis of genital tract in women. EFFECT: strain indicated above, high effectiveness of correction. 3 tbl, 3 ex
The present brow lift and freeze kit and method provides an instant brow lift without the need for surgery or Botox® injections. The kit comprises a lifting and freezing composition, an applicator, an astringent cleanser, and cotton swabs. Optionally, the kit may include adhesive strips for placing on the user&#39;s forehead and/or glabella during application of the lifting and freezing composition. The lifting and freezing composition is spread across the user&#39;s brows. The applicator is used to lift and sculpt the eyebrows into a desirable shape. The lifting and freezing composition is allowed to dry. After the drying, any excess flax seed composition above the brows is removed by dabbing with a swab wetted with astringent cleanser. Optionally, an adhesive strip may be affixed to the user&#39;s forehead and/or glabella to prevent muscle movement of the upper face during application and drying of the lifting and freezing composition.
NEW MATERIAL:A compound of formula I (R&lt;1&gt; is H, alkyl, alkenyl, phenyl which may be substituted; R&lt;2&gt; is alkyl; R&lt;3&gt; is H, methyl; where when R&lt;1&gt; is phenyl, R&lt;2&gt; is not 3C alkyl). EXAMPLE:N-Allyl-N-acetyl-O-methylhydroxylamine. USE:Paraticide: it shows high paraticidal effect against a variety of parasites in a wide range of animals. It can be given simply with steady efficacy. Further it has low toxicity and high safety. It is produced with industrial advantages. PREPARATION:A compound of formula II and a halide of formula III (X is halogen) are stirred in a solvent such as acetone in the presence of an acid acceptor such as sodium methoxide at 0-100 deg.C for 1h to 3 days to give the compound of formula I .
FIELD: medicine, virology. SUBSTANCE: invention relates to preparing an antirotaviral immunoglobulin that can be used for immunoprophylaxis and immunotherapy of rotaviral infection. Invention relates to development of a method of preparing an antirotaviral immunoglobulin that involves an isolation of normal immunoglobulin by fractionation of usual donor serum blood with ethanol at minus temperatures by Cohn&#39;s method, detection of antibodies to rotavirus in reaction of inhibition of nondirect hemagglutination and combination of preparations at titer values of antibodies to rotavirus 1: 160, not less. Invention ensures to realize large-scale method and obtain large amounts of a preparation showing high specific activity. EFFECT: improved method of preparing, increased yield of the end product. 1 tbl, 1 dwg, 1 ex
A medical device having enhanced ultrasonic visibility is provided. The device permits localized drug delivery, probe positioning, fluid drainage, biopsy, or ultrasound pulse delivery, through the real-time ultrasound monitoring of the needle tip position within a patient. The device permits controlled dispersion of a drug into solid tissue, the lodging of particles into solid tissue, and drug delivery into specific blood vessels. As a needle is inserted, a fluid that contrasts echogenically with the organ environment is injected into the patient. The fluid travels a brief distance before being slowed and stopped by the patient&#39;s tissue and this fluid flow will be detectable by ultrasound. The needle position during insertion will be monitored using ultrasound until it is at the desired point of action. A therapeutic drug is then delivered or a probe inserted through the needle to perform therapies such as tumor ablation using RF heating. The fluid flow rate may be adjusted during insertion to maintain a properly defined image of the needle tip. At the point of action, the echogenic fluid can be pulsed, repeatedly and at varying flow rates, until the fluid dispersion pattern is satisfactory and the drug can then be delivered. Ultrasound can also be delivered through the. needle using a transducer mounted in the handheld assembly.
The present invention discloses a kind of Folium hydrangeae strigosae having Weight-reducing health effect, uses Ampelopsis cantoniensis （Hook. et Arn.） Planch. var. grossedentata Hand.-Mazz., Semen Euryales, Folium Nelumbinis, Semen Phaseoli, Herba amaranthi ascendentis, Radix et Bulbus Allii tuberosi and EM original solution etc. to be prepared from.Ampelopsis cantoniensis （Hook. et Arn.） Planch. var. grossedentata Hand.-Mazz., Semen Phaseoli, Folium Nelumbinis and Herba amaranthi ascendentis heat-clearing and toxic substances removing, inducing diuresis and reducing edema, Semen Euryales reinforcing the kindey to control nocturnal emission, tonifying spleen and stopping diarrhea, invigorating middle warmer removes sudden and violent disease, benefit vital essence, Qiang Zhi, make us normal hearing and eyesight, compatibility uses the drug effect strengthening clearing heat, detoxicating, dispelling dampness detumescence, has again astringent or styptic treatment for spontaneous sweating, spleen reinforcing and blood benefit vital essence, the effect of hard muscles and bones, Folium Nelumbinis, Semen Euryales, Semen Phaseoli and Herba amaranthi ascendentis detoxification and promoting urination diuretic simultaneously, invigorating the spleen and replenishing QI takes energy Weight-reducing and lipid-lowering, body shaping of making light of one&#39;s life by commiting suicide for a long time again.EM original solution anti-inflammation and sterilization, except stench abnormal flavour, anti-corrosive fresh-keeping, decomposes poisonous and harmful substance, hence it is evident that strengthens gastrointestinal and resists function of diseases.Folium hydrangeae strigosae is sweet, and prevention effect is definite, and valency is held concurrently, and the easy people that draw materials like often to drink.
A method and apparatus for correcting refractive errors of the eye are disclosed. Accelerated reshaping of the corneal tissue is accomplished by administering one or more enzymes and/or other agents to the eye which temporarily soften the cornea. The cornea is thereafter fitted with a rigid contact lens or a series of lenses which have a concave curvature that will correct a refractive error. The softened cornea then rapidly reshapes its convex curvature to the concave curvature of the contact lens or series of lenses, thereby rendering the eye emmetropic. The enzymes and/or other agents then dissipate from the cornea, and the cornea &#39;hardens&#39; to retain the new emmetropic shape. After &#39;hardening&#39; has occurred, the lens rendering the eye emmetropic is removed.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an androgen receptor down-regulatory-associated protein (ARDAP) which binds to an androgen receptor (AR) and reduces the ability of the receptor to transactivate, and to provide a nucleic acid sequence encoding the protein.  &lt;P&gt;SOLUTION: The invention relates to the ARDAP protein overexpressed in breast cancer cells (relative to adjacent normal cells), and has a specific amino acid sequence. The nucleic acid has a specific base sequence encoding it. A vector including the nucleic acid which encodes the transactivated product, is transduced to a cell, for example, breast cells and expressing the transduced product in the cells. Measuring levels of the ARDAP gene expressing or activity level of the ARDAP of a sample from a subject to detect presence or absence of a danger of onset of breast cancer, and to carry out isolation of compound for therapy of the breast cancer.  &lt;P&gt;COPYRIGHT: (C)2004,JPO&amp;NCIPI
A system and method for tracking and monitoring persons. To begin, the presence of a user at a location is determined when the userID is identified in the primary input data. The user&#39;s motion are determined using the primary input data and the secondary input data when the presence of the user at the location is determined. The position of the user is determined using the secondary input data when the presence of the user is determined. A matching algorithm is used to identify reference data that is similar to the primary input data or secondary input data and thereby determines completion of a user task of the user. transmit, via a communications device communicatively coupled to the control circuit, a notification is transmitted to a user computing device for conveyance via the user interface when completion of the user task is determined.
In accordance with the useful model, the cosmetic composition contains in weight %: lyophilized extract of snail mucus and lyophilized extract of snail eggs, while the quantity of the components is the following: lyophilized extract of snail mucus from 0.001 to 0.5, lyophilized extract of snail eggs from 0.001 to 7, argan oil from 0.10 to 10, anti-inflammatory agent from 0.01 to 0.50, humectantsfrom 1 to 10, alpha-hydroxy acid from 0.01 to 1, retinyl palmitate from 0.01-0.5, tocopheryl acetate from 0.1 - 2,0, D-panthenol from 0.1 to 5.0, preservative from 0.05 to 1.20, chelate compound from0,05 to 0,2, perfume composition from 0.0 to 0.7, thickener from 2 to 5, antioxidants from 0.01 to 1.00 and deionised water up to 100, and in some cases additionally contains a surfactant or regenerating additive and/or water/oil stabilizing composition and/or solvents of oil components. The composition of the useful model provides a surprisingly rapid effect. The effect of its use according to the purpose becomes evident between the 5-th and the 10-th day of the treatment of the skin areas. In accordance with the useful model, the cosmetic composition has a very quick and positive effect on acne and signs of acne, rosacea, age spots and freckles, wrinkles and frown lines, including &#34;crow&#39;s feet&#34;, scars, stretch marks, dead skin cells that need exfoliation. The cosmetic composition retains the biological activity of the active substance for a long period of time. The enzymes contained in the cosmetic composition retain their conformational integrity and activity, respectively. This activity is controllable depending on the use of the composition according to the useful model. The shelf life of the composition according to the useful model is extended significantly and hence the possibilities for its storage, which does not require special conditions.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an exothermic composition having excellent dispersion stability of zeolite and an exothermic cosmetic having excellent usability without settling the zeolite during preservation and without requiring shaking stirring during use and further excellent beauty culture effects and to provide a method for beauty culture caring and a method for stabilization in order to stably disperse powder in the composition.  &lt;P&gt;SOLUTION: The exothermic composition comprises the zeolite (A), a dihydric alcohol (B) and a polyhydric alcohol (C) having three or more hydroxy groups, a hydroxide (D) of an alkaline earth metal and a surfactant (E). The cosmetic comprises the composition. The method for beauty culture caring comprises using the cosmetic. The method for stabilization comprises stably dispersing at least one kind of powder in a substantially nonaqueous medium containing the polyhydric alcohol. In the method, the medium contains at least the one kind of the hydroxide (D) of the alkaline earth metal and the surfactant (E).  &lt;P&gt;COPYRIGHT: (C)2004,JPO
The present invention provides chimeric viral vectors which have both the capacity to infect host cells efficiently and the capacity to integrate their genomic material into the host cell&#39;s genome. Therefore the invention provides such a chimeric viral vector which comprises a functional packaging signal derived from a first virus and an integration means derived from a second virus. Typically viruses capable of integrating their material into a host cell genome, preferably provided with additional genetic material introduced therein by recombinant means, do not have much room for insertion of such additional genetic material or are not very well capable of infecting every wanted host cell. Typically viruses that are very well capable of infecting many host cells either also do not have a high insertion capacity or do not integrate their genomic material provided with said additional genetic material into the host cell&#39;s genome. The present invention provides a solution to the problem of getting large inserts integrated into a host cell&#39;s genome at an efficient infection rate by combining the properties of efficiently infecting viruses with efficiently integrating viruses. A good working example of the present invention is provided in a combination of adenovirus and adeno associated virus.
&lt;P&gt;PROBLEM TO BE SOLVED: To provide an extract-containing composition for moisture dispersion that is powdered and easily handleable and becomes dispersion having excellent transparency when dissolved in water, never degenerates under refrigeration/freezing and provide beverage using the same.  &lt;P&gt;SOLUTION: Two pts.wt. of moisture ethanol is added to 1 pt.wt. of crushed propolis and they are stirred, extracted and filtered to obtain a propolis extracted solution. The propolis extraction solution in an amount of 586 g is mixed with saponin in 100 g, lecithin in 45 g and polyglycerol fatty acid ester in 197 g and they are stirred and emulsified to obtain clear and water-soluble propolis solution. Two grams of this water-soluble propolis solution is mixed with 10 g of sugar powder and the mixture is dried in a dryer.  &lt;P&gt;COPYRIGHT: (C)2006,JPO&amp;NCIPI
The invention provides novel vectors derived from adenovirus which are specifically suitable for use in methods of gene therapy. &lt;??&gt;The vectors have a deletion compared to wild-type adenovirus in that the E1 region is not present in a functional manner. &lt;??&gt;Additionally the vectors are characterized in that they do contain a part of the E3 region of adenovirus which is biologically functional. This results in vectors which do normally not lead to expression of adenoviral proteins, but which in the cases where such proteins do become expressed will repress the host&#39;s immunological response to said proteins. Thereby host cells infected (provided) with the vector will live longer. Therefor the product introduced into said cells providing the therapy will be produced in larger amounts, or at least for a prolonged period. Preferably the vector comprises genetic information for antisense therapy, or for genes which will combat tumors, such as genes encoding cytokines, preferably IL-1, or so called suicide genes, such as Herpes Simplex Virus thymidine kinase. &lt;??&gt;Methods for producing said vectors and methods of gene therapy or uses therein are also disclosed.
&lt;P&gt;PROBLEM TO BE SOLVED: To efficiently produce gel particles having a uniform particle diameter without causing problems of solvents derived from a step of dispersion without carrying out the step of dispersing a raw material solution for forming the raw material solution of the gel particles into a micro-particle state in an organic solvent.  &lt;P&gt;SOLUTION: A method for producing the gel particles is carried out as follows. The raw material solution prepared by dissolving a polymer modified with a xanthene dye and a hydrogen donor in a hydrophilic liquid or a lipophilic liquid is irradiated with visible light to cross-link and cure the polymer in the presence of the hydrogen donor. Thereby, the gel particles are produced. In the process, the raw material solution is sprayed as droplets over the vapor phase. The resultant droplets of the raw material solution are then irradiated with visible light and made to gel.  &lt;P&gt;COPYRIGHT: (C)2007,JPO&amp;INPIT
&lt;P&gt;PROBLEM TO BE SOLVED: To provide a face mask for preventing the saggy face by tightening the skin of the face through raising up the cheek line from the mouth side, of which decay causes the sagging or the wrinkles of the skin of the face.  &lt;P&gt;SOLUTION: The face mask to be put on the face is formed of a stretch fabric. The mask body is right/left symmetrically formed and provided with a pair of main belts to be fastened around the rear of the top and a pair of assisting belts to be fastened around the back of the head. The ends of the belts are engaging-retained by a hook-and-loop fastener, respectively. The mask has ear-holes in the ear positions of the face, a mouth hole in the mouth position, a chin hole below the mouth and a rubber band provided on a lower edge of the jaw position of the mask.  &lt;P&gt;COPYRIGHT: (C)2010,JPO&amp;INPIT
FIELD: medicine, gastroentrology. SUBSTANCE: invention relates to parapharmaceutical industry producing preparations of curative and prophylactic designation that can be used for prophylaxis and accessory treatment of gastritis, duodenitis and colitis of different etiology, ulcer disease. Invention proposes biologically active supplement for prophylaxis and supporting therapy in digestive tract diseases. Supplement is based on medicinal plants and comprises the following components: glabrous licorice roots dry extract, elecampane roots dry aqueous concentrate, dry concentrates of Saint- -John&#39;s-wort herb tincture, propolis and carrot juice, flower pollen, vitamin E, zinc sulfate, aluminium hydroxide, milled oat, starch, calcium stearate, talc and sugar taken in definite weight ratios. The use of this supplement results to improvement of indices of T-cellular immunity revealing due to increased level of T-helpers, clinic indices in patients with pathology of digestive organs being for short times. EFFECT: valuable medicinal properties of supplement. 2 cl, 5 tbl, 4 ex
PURPOSE:To make a slightly soluble drug into ultrafine particles and to improve and promote absorption of slightly soluble drug in digestive tube by blending a low-molecular saccharide with the slightly soluble drug and grinding. CONSTITUTION:A mixture of a slightly soluble drug and a saccharide (e.g. glucose) or a sugaralcohol is ground by high-speed stirring or impact grinding and the slightly soluble drug is made into ultrafine particles having &lt;=1 micron. 1 pts.wt. of the main drug is used with 1-50 pts.wt. saccharide. The slightly soluble drug has &lt;=5mg/ml water solubility at 20 deg.C and has insufficient absorption when made into solid preparation by conventional pharmaceutical manufacturing. The drug is nifedipine, indomethacin, cortisone, etc. The ultrafine particles of the drug is contained as an active ingredient and can be pharmaceutically manufactured.