Document type: Resume

FF PRINGIPAL INVESTIGATOR/PROGRAM DIRECTOR (Last, first, midate}. Ba Idini { xiulia BIOGRAPHICAL SKETCH Give the following information for the key personnel and consultants and collaborators. Begin with the principal investigator/program director. Photocopy this page for each person. NAME Witkin, Joan Wharton. POSITION TITLE Research Scientist EDUCATION (Begin with baccalaureate or other initial professional education such as nursing, and include postdoctoral training.) INSITITUTION AND LOCATION FIELD OF STUDY Mt. Holyoke College, S.Hadley, MA BA, MA 1955,'57 |Zoology Columbia Univ. NY, NY PhD 1981 Physical Anthropology Col. Univ., Coll. P.&S., NY, NY Postdoc 1981-'83 |Neurosci/Neuroendocr RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list, in chronological order, previous employment, experience, and honors. Key personnet include the principal investigator and any other individuals who participate in the scientific development or execution of the project. Key personnel typically will include all individuals with doctoral or other professional degrees, but in some projects will include individuals at the masters or baccalaureate level provided they contribute in a substantive way to the scientific development or execution of the project. Include present membership on any Federal Government public advisory committee. List, in chronological order, the titles, all authors, and complete references to all publications during the past thres years and to representative earlier publications pertinent to this application. DO NOT EXCEED TWO PAGES. PREVIOUS APPOINTMENTS and RESEARCH EXPERIENCE: 1991 - Research Scientist, Dept. Anat. & Cell Biol. Columbia Univ. P.&S. 1985-'91 Associate Research Scientist, Dept. Anat. & Cell Biol. Col. U. P.&S. 1982-'85 Postdoctoral fellow, Dept. Anat. & Cell Biol. Col. U., P.&S. 198 1-'82 Staff Associate, Dept. Anat. & Cell Biol. Col. U., P.&S. 1980 Graduate Research Assistant, Dept. Anthro., Col, Univ. 1959-'61 Instructor, Zoology Dept., Hunter College, NY, NY HONORS: 1955 Phi Beta Kappa 1981 Grant from Brookdale Institute on Aging and Adult Human Development 1982 National Research Service Award PUBLICATIONS: 1997 Witkin JW, O'Sullivan H, Ferin M GnRH perikarya in medial basal hypothalamus of pubertal femal rhesus macaque are invested with hypertrophied glia. (Submitted) 1997 Wang G, Witkin JW, Hao, G, Bankaitis VA, Scherer PE, Baldini, G Syndet is a novel SNAP-25 related protein expressed in many tissues. J. Cell Science 110:505-513. 1997 Witkin JW Anatomical evidence for synchronized neuronal networks: GnRH system Microscopy Research and Technique (Invited) 1996 Witkin JW Effects of ovariectomy on GnRH neuronal morphology in rhesus monkey (Macaca mulatta}. J. Neuroendocrinology 8:601-604. 1995 Witkin JW, O'Sullivan H, Ferin M GHal ensheathment of GnRH neurons in pubertal female rhesus macaques. J. Neuroendocrinology 7:665-671. 1995 Sullivan KA, Witkin,JW, Ferin M, Silverman AJ Gonadotropin-releasing hormone neurons in the rhesus macaque are not immunoreactive for the estrogen receptor. Brain Res. 685:198- 200. 1995 Witkin JW, O'Sullivan H, Silverman AJ Novel neuronal associations among GnRH neurons. Endocrinology 136:4323-4330. 1995 Witkin JW and Romero M-T Comparison of ultrastructural characteristics of of gonadotropin- releasing hormone (GnRH neurons in prepubertal male rats. Neuroscience 64:1145-1151. 1994 Witkin JW Electron microscopic methods for determining changes in the density of synaptic input to neurons in the aging brain. Neuroprotocols 4:235-239. 1994 Silverman AJ and Witkin JW Biosynthesis of gonadotropin-releasing hormone during the rat estrous cycle: a cellular analysis. Neuroendocrinology 59:545-551. 994 Romero M-T, Silverman AJ, Wise PM and Witkin JW Ultrastructural changes in gonadotropin- releasing hormone neurons as a function of age and ovariectomy in rats. Neuroscience 58: 217-225. 994 Witkin JW, Xiao E, Ferin M and Silverman AJ FOS expression in the gonadotropin-releasing hormone (GnRH) neuron does not increase during the ovarian steroid-induced GnRH surge in the rhesus monkey. Endocrinology 135:956-961. 1992 Witkin JW Reproductive history affects the synaptology of the ageing gonadotropin-releasing hormone system in the male rat. J. Neuroendocrinology 4:427-432. PHS 398 (Rev. 9/91} {Form Page 6) Page Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b. FF 50722487