anirudh1112/corrected-tobacco-dataset-with-ocr huggingface dataset:
Document type: Letter

JUL-27-93 TUE 15346 JAPS~OLSON COMPANY FAX NO, 6125208280 P. 02 Tobacco Company 919-741-3000 Winston-Salem, N.C, 27102 . July 28, 1993 To Our Retail Customers: Effective with shipments to all our direct buying cuslomers on Monday, August 9, 1993, the list prices for tha following RJR brands will be reduced, -—-Piemium Brands Discount Brands WINSTON MORE DORAL SALEM NOW STERLING CAM CENTURY VANTAGE IMPORTANT NOTE: Specially marked WINSTON $4,00/5.40 of product and other specially marked discount/sniped promotional product will not be further reduced as these already reflect a promotional price reduction. We will maintain current pricing on WINSTON $4.00/$.40 specially marked product while these promotional supplies last. Contact your cigarette supplier for availability and additional information. By maintaining your inventories on WINSTON $4.00/8.40 specially marked product and other specially marked . product, you can continue to offer to your.customers a low price on these brands. COnsEmMehs” Our naw pricing effectively creates two price tiers for our products, premium and discount. All brand styles within each pricing tier (regular/King/ 100/120) will be priced the same. We suggest that you consult with your cigarette supplier or chain headquarters for complete detalls of price changes that may have resulted from our announcement. _ tls recommended that you sell through on-hand higher priced inventories prior to rolling back your retall prices to consumers, We also suggest you reset your price for all brand styles in the premium and discount ‘categories at one time, thereby eliminating confusion for both stora personnel and customers. Instead of trying to target a certain date, our objective Is that you have maximum fiexibility In resetting your prices as” most appropriate for you based upon your store's inventory situation, We will not offer a retall participation/inventory protection program. Each retailer is In the best position to taitor its pricing strategies to fit its particular Inventory levels, and It would be extremely difficult for us to audit the Inventory of over 300,000 retali outlets and offer a fair reconciliation of on-hand Inventory. During the week of August 2, 1993, you will receive rallback point-of-sale materials to use in communicating your new lower prices to your customers. Thank you for your assistance in the marketing of our products. . Ri. Reynolds Tobacco Company "We work for smokers.” 9642 TIeTs
Document type: Report

- 3 - PLANS FOR 1989 ol S co es) Ss bh u W wo DENTIFICATION OF CHEMIC co. ENTS Serve as resident expert in the area of Fourier transform infrared spectrometry as applied to the analysis of complex mistures and in the area o NMR spectrometry. Particular attention if directed toward the hyphenated technique of gas chromatography/matrix isolation/Fourier transform/IR spectrometry. Within this same general category , serve as consultant in the area of solid state IR with particualr attention directed toward IR microscopy. 2) FREON REPLACEMENT Continue to explore the applications of micro Ge technologies to the analysis of volatile materials in process streams. 3) FLAVO Further development of the new technique SFC and SFE will be explored. Attention will be directed toward the production of candidate flavor material from tobacco and other natural products(SPA). SFC will be used to characteriz the thermally labile and high molecular weight materials whose prosence has been indicated in tobacco extracts by previous experiments, Attempts will be made to wed SFE with GC in an integral piece of instrumentation. Conceivably a unit described by SFE/GC/IR/MS could be developed. 4 PACKAGING TECHNOLOGY Continue to work as coinvestigator into he design and construction of new instrumentation directed at the determination of the permeation rates of complex mixtures through barrier materials (films). Conduct experiments describing the optimun operating parameters. Pursue a patent application in this area of instrumentation design. 5)SP Perform specialized analyses as required 6 IMPROVE CHEMIC N s Continue to serve as coinvestigator into the installation and setup of the ne\ hyphenated technique(GC/IR/MS) for improved responce times for analytical requests. Compare the advantages and disadvantages of the GC/VPIR with that of GC/MIIR in the analysis of samples relevent to company needs. Pursue the publishing of an article describing the results of the investigation. 7 NPT Continue to serve as contac point and cooridinator of all analytical requests of the division originated from NPT. 8 )IMPROVE MEASURE T s Pursue new areas of analytical development targeted directly at the needs of the company. Areas to include but not be restricted to SFE, SFC, MTFTIR,MDGC ,NMR,etc, 9 )PROFESSIOINA EVELO T Actively continue professional development via published articles in the peer reviewed literature and presentations at professional meetings related to the analysis of complex materials as required fro company projects,
Document type: Letter

THE Counc. For Tospacco Researcu~U.S.A., Inc. ‘ 900 THIRD AVENUE NEW YORK, N.Y. 10082 JAMES B GLENN, M.D. CHATRMAN OF THE BOARD GHIEP EXECUTIVE OFFICER June 19, 1991 R.K. Boutwell, M.D. 2935 Harvard Drive Madison, WI 53705 Dear Roz: First of all, we miss you. The SAB continues to roll along, but your wisdom and humor were always admired. Now, I need the wisdom especially. It is possible that at some time in the future there may be some legal action which would touch CTR. We need someone of stature who would be willing to plainly state the facts, i.e., that the research supported by CTR over the years was never influenced by our sponsors and that the award of funds for biomedical research were made with total objectivity by the SAB. No one is better qualified to do this than you are. Frankly, this matter may never come up. The first anticipated possibility of needing such testimony is some two or three years in the future. However, our lawyers do want to know whom they might call upon, and I hope you will agree to do this. Needless to say, you would be reimbursed for your time and expenses in connection with anything of this sort. If you feel that you would be able to help me; I would appreciate it if you would send along a copy of your current curriculum vitae and bibliography. I will in turn pass them along to our attorneys. I hope that you and Lou are doing well and I send my warmest personal regards always. Thanks and all best wishes. Sincerely, - mes F. Glenn, M.D. JFG/ff *
Document type: Memo

PHILIP MORRIS INCORPORATED INTER-OFFICE CORRESPONDENCE TO: FROM: SUBJECT: 120 PARK AVENUE, NEW YORK, N.Y 10017 John Burke DATE: September 20, 1988 Phyllis Cowart RECORDS MANAGEMENT REVIEW - PM MANAGEMENT - COMPENSATION & EMPLOYEE RELATIONS The Records Management group will conduct a review of the files maintained in your office. The objectives are: To determine that the files retained are in conformance with the Records Retention and Vital Records (if applicable) Schedules. To update the Records Retention Schedule. To review on-site file alternatives; i.e., offsite records centers, Carlstadt or QRSA, and the use of microform in lieu of hard copy documents. Please note that Cecilia McLaughlin will meet with Ruth on Tuesday, September 27 at 10:00 to review the records maintained in your office. If this time is inconvenient, please call Cecilia on extension 2933 to reschedule. PIC/ca 1704C ec: L. A. Cafaro C. McLaughlin | S41 SPOT O02
Document type: Memo

2 RECEIVED AUG 7 1984 _JOHN ALAR MEMORANDUM August 6, 1984 TO: John Alar Tom Sandefur Dick Blott Lanny Butler Don Christensen FROM: Sales Planning SUBJECT: NATIONAL GENERIC SHIPMENTS REPORT Attached is the National Generic Shipments Report for the week ending August 3, 1984. Also attached is a list of customers who have signed generic contracts. You will receive up dated reports each Monday. Sales Planning Attachments ZOZLZ00O9ES
Document type: Email

2075711719 Hardin, Chris . | From: Hardin, Chris Sent: Friday, March 31, 2000 8:53 AM To: Desel, Paula Subject: RE: PM USA Intranet - Legal's Site If you want, although I'li have copies in Richmond. | also thought of adding a link to the Litigation site just announced by Wall.
Document type: Email

2085269110 Teitelbaum, Shari Z. From: Teitelbaum, Shari Z. Sent: Wednesday, October 34, 2001 5:16 PM Falvo, Jeff J. Subject: Joint Christmas Party?? Hi Jeff. Thought it would be a good idea for our 2 groups to celebrate the holidays together. Maybe a joint bowling outing? po you have any other ideas? Let me know what you think so we can pin down a date. hari 24
Document type: Email

From: Smith, Jan Fulton To: Moskowitz, Seth W. cc: BCC: Primary Date: 10/8/1999 1:56:43 PM Last Modified Date: 1999-Oct-08 13:56:43 Last Touched Date: Sent Date: 1999-Oct-08 13:56:43 Received Date: 1999-Oct-08 13:56:43 Subject: Corporate Responsibility: Marketing{F} SEAN OAT Attachments: CorpRespon-website.doc seth, fyi only. jan -----Original Message----- From: Goho, Barbara B. Sent: Friday, October 08, 1999 1:33 PM To: Crosslin, Carole S.; Smith, Jan Fulton Subject: FW: Corporate Responsibility: Marketing Chuck approved the corp. responsibility copy w/changes. FYI, please see the changes. -----Original Message----- From: Blixt, Charles A. Sent: Friday, October 08, 1999 1:26 PM To: Goho, Barbara B. Subject: FW: Corporate Responsibility: Marketing My comments highlighted on the attached (not limited to the first two paragraphs). From: Goho, Barbara B. Sent: Tuesday, September 21, 1999 10:05 AM To: Blixt, Charles A. Cc: Turner, Jettie R. Subject: Corporate Responsibility: Marketing The attached document is for “Inside RJR"/"Corporate responsibility” section of the RJR website. Please review the first two paragraphs -- I've redrafted per Tommy Payne's request. He has asked that you approve the rewrite. I believe you have reviewed and approved the rest of the document already. RJR0000001523059021 70015 7782 SSA AAMAS AAA VASA SAAS AAO TA UNSAVORY ANA AAEM 82248 P6leS
Document type: Email

-----Original Message----- From: Lattanzio, Ted Sent: Friday, July 23, 1999 11:25 AM To: Ostern, Eric; Fisher, Scott Cc: Paluszek, Matt; Kiley, Deborah L.; Culley, Liz; Goldman, Rochelle Subject: RE: Maine No | don't have this info. Matt should be able to get this from either one of his contractors or Dick G. VOvVLZ8Z1202¢
Document type: Email

2085788705 Dierkes, Jo S. From: Lewis, Jane Y. Sent: Friday, January 25, 2002 8:40 AM To: Nardell, Lisa M. Subject: RE: Game Plan Thanks, Jane
Document type: Resume

* + BIOGRAPHICAL SKETCH William B. Wood Principal Investigator and Professor Education: Institution and Location Degree Year Field of Study Harvard College, (Cambridge, MA) AB. 1959 Chemistry Stanford University, (Palo Alto, CA) Ph.D. 1963 Biochemistry University of Geneva, (Switzerland) Postdoctoral 1963-64. Mol. Genetics Professional Experience: Dept. of Biochem., Stanford Univ., USPH Predoctoral Trainee, 1959-1963 (with Paul Berg). Dept. of Biophysics, Univ. of Geneva, Switzerland. NAS-NRC Postdoctoral Fellow, 1963- 1964 (with Werner Arber). Dept. of Biology, California Institute of Technology. Assistant Professor, 1965-1968. Associate Professor, 1968-1969. Professor, 1970-1977. Dept. of Molecular, Cellular and Developmental Biology, Univ. of Colorado, Boulder, Visiting Professor, 1975-1976. Professor, 1977-present. Chairman, 1978-1983. Associate Chairman 1988-1992. Honors: U.S. Steel Award in Molecular Biology, 1969; National Academy of Sciences, election to membership, 1972; Guggenheim Fellowship, 1975-1976; American Academy of Arts and Sciences, election to membership, 1976; Harvey Socicty Lectureship, 1978; NIH] MERIT Awardee (N.I.C.H.D.) 1986-1996; elected Fellow of the American Association for the Advancement of Science, 1989. Representative Research Publications, 1977-1989 (from a total of 72): Edgar, R. S., and Wood, W. B. (1977) The nematode Caenorhabditis elegans: a new organism for intensive biological study, Science 198: 1285-1286. Laufer, J. S., Bazzicalupo, P., and Wood, W. B. (1980) Segregation of developmental potential in early embryos of C. elegans. Cell 19: 569-577. Wood, W. B., Hecht, R., Carr, $., Vanderslice, R., Wolf, N., and Hirsh, D. (1980) Parental effects of genes essential for carly development in C. elegans. Dev. Biol. 74: 446-469. Strome, S. and Wood, W. B. (1982) Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvac, and adults of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 79: 1558-1562. Johnson, T. E, and Wood, W. B. (1982) Genetic analysis of lifespan in Caenorhabditis elegans, Proc. Natl. Acad. Sci. USA 79: 6603-6607. Edwards, M. K. and Wood, W. B. (1983) Location of specific messenger RNAs in Caenorhabditis elegans by cytological hybridization. Dev. Biol. 97: 375-390. Strome S., and Wood, W. B. (1983) Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos. Cell 35: 15-25. Menecly, P. M, and Wood, W. B. (1984) An autosomal gene that affects X chromosome expression and sex determination in Caenorhabditis elegans. Genetics 106: 29-44. Schierenberg, E. and Wood, W. 13. (1985) Control of cell-cycle timing in eatly embryos of Caenorhabditis elegans. Dev. Biol. 107: 337-354, Wood, W. B., Meneely, P., Schedin, P. and Donahue, L. (1985) Aspects of dosage compensation and sex determination in Caenorhabditis elegans, CSH Symp. Quant. Biol., 50: 575-583. CSH Laboratory, Cold Spring Harbor, NY.
Document type: Email

Forwarded by Noel Clinard/HuntonWilliams/Bravo on 11/15/99 11:44 AM MAY CONTAIN CONFIDENTIAL WORK PRODUCT, JOINT DEFENSE, OR PRIVILEGED ATTORNEY-CLIENT COMMUNICATIONS IN CONNECTION WITH ONGOING AND THREATENED LITIGATION as Noel Clinard MYO 4418/99 11:30 AM Ta: Noel Clinard/HuntonWilliams/Bravo@ Bravo cei Subject: Fax 3934 from 18043448822 to 312.616.2806. 35 pages.{Received) V98L989r202
Document type: Resume

Noboru FI Prncipal Invesuigator:Program Director ‘Last. frst. magie. _ Sueoka, BIOGRAPHICAL SKETCH Gwe the following information for the key personnel and consultants anc collaborators. Segin with the principal investigator‘program director. Photocopy this page for each person NAME ; POSITION TITLE Risa Ohkawa _ Doctoral candidate-Sth year graduate studeret EDUCATION | Begin with Saccalaureate or other initial protessiona!l educavon. sucn as qursing, and include postdoctoral training } ; YEAR INSTITUTION AND LOCATION. i DEGREE CONFERRED | FIELD OF STUDY ss ccs sane : Massachusetts Institute of Technology | | = rT a oe Cambridge, MA S. B 1928 Life Sciences | i | 1 RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present pasition, list. n cnrcnological order, previous employment. expererce arc honors. Key personnat include the principal investigator and any other individuals who participate :n the scientific development ar execution of "re arciect Key personnel typicatly will nciude all individuals with doctoral or other professional degrees. Dut in some projects will include individuals at '"e “asters cr baccataureate level provided they contnbute in a substantive way to the scientific development or executian of the project. Inciude present memcersrip or any Federal Government public advisory committee. List, in chronological order, the titles. ail authors, and complete references to all publications Guneg tre past three years and to representative earlier publications pertinent to this application. OO NOT EXCEED TWO PAGES. Doctoral candidate: University of Colorado, Boulder, Molecular, Cellular and Developmental Biology department August 1988-present Research Assistant: Salk Institute San Diego, CA May 1988-August 1988 Minority opportunities program: Salk Institute San Diego, CA January 1988-February 1988 May 1987-August 1987 May 1986-August 1986 May 1985-August 1985 National Science Foundation Graduate Fellowship: awarced 1989 currently in third and final year University of Colorado Predoctoral Fellowship: PHS 398 (Rev. 9/91) (Form Page 6) Page Number pages consecutivaly at the bottom throughout the application. Do not use suffixes such as 3a. 3b. 1988 1993 1994
Document type: Email

2075311121 Printed By: Kelly Rubin MAY CONTAIN CONFIDENTIAL WORK PRODUCT, JOINT DEFENSE, OR PRIVILEGED ATTORNEY-CLIENT COMMUNICATIONS IN CONNECTION WITH ONGOING AND THREATENED LITIGATION iy A. Jennifer Cygnor am" 94/14/99 05:12 PM Ta: National Counsel cc: Subject: Yukon-Kuskokwim Health Corp.: Removal
Document type: Email

--~-Original Message---- : : 40607 53721 From: Gitbert, Margaret Sent: Thursday, August 17, 2000 2:25 PM To: Alonso, Hector; Lilly, A. Cliff; Lewis, Jane Y.; Sweeney, Randy; Koller, Kent B.; Shafer, Ken H.: Hajaligol, Mohammad R.; Cox, Ken A.; Deevi, Seetharama C.; Losee, Bruce Ce: Lipowicz, Peter J. ” Subject: Dr. Manuel Marquez Visit to PM Pete Lipowicz has invited Dr. Manuel Marquez from Kraft Foods to visit Philip Morris on August 30 and August 31. Dr. Marquez's area of study at Kraft is Nanotechnology. An abbreviated version of his CV follows this e-mail. He will be giving a presentation on Wednesday, August 30, at 3:00 in R&D/A1. As soon as the abstract of the taik is received, it will be distributed. The following is a “tentative” schedule for Dr. Marquez. !f you are available, Pete would like to invite you to spend some time with him (approximately 30 minutes each) during his free time and for lunch (wines seas in red). You are also invited to go to dinner Wednesday night. Please let me know if you will attend the dinner so reservations can be made. Please look at the schedule below and let me know if you would be available to spend some time with him and if so, what time slot you prefer. Please let me know by August 25, 2000. A final schedule will be distributed as soon as everything is confirmed. Wi dnesday, August 30 Seminar 4: 00 p. m. Post aoe Questions 7:00 p. m. - - 9:00 put m. Dinner (location to be determined) Th rsday, August 31 MANUEL MARQUEZ KRAFT FOODS Research & Development, 801 Waukegan Rd.
Document type: Memo

# PAGE: 1 PHILIP MORRIS USA INACTIVE RECORDS DISPOSAL NOTICE DATE: 01/12/1995 TO: 20TH STREET FACILITY FROM: RECORDS MANAGEMENT DEPARTMENT THE FOLLOWING RECORDS ARE SCHEDULED FOR DISPOSAL AS OF JANUARY 1, 1995. RETURN THIS NOTICE TO THE RECORDS MANAGEMENT DEPARTMENT (M/C - EWB) WITHIN 30 DAYS. TOTAL RETENTION CREATION BOX RECORD CATEGORY CODE PERIOD DATE * NUMBER 01 MFP-460 BO475 - C+1 01/01/93 009244 01 MFP-460 BO477 - c+1 01/01/93 009251 O01 MFP-460 C1068 - C+3 01/01/91 007506 Ol MFP-460 P1004 - err 01/01/93 009245 01 MFP-460 P1012 - C+2 01/01/92 009240 Ol MFP~-460 P1013 - Ct+4 01/01/30 005610 * RECORDS CREATED FROM JANUARY 1 THROUGH DECEMBER 31 OF THE CALENDAR YEAR I/WE APPROVE THE DISPOSAL OF THE ABOVE RECORDS (UNLESS AN EXPLANATION IS ATTACHED OF WHY ANY OF THESE RECORDS SHOULD NOT BE DISPOSED) AND I/WE CERTIFY THE RECORDS APPROVED FOR DISPOSAL HAVE BEEN REVIEWED AGAINST APPENDIX A OF THE PHILIP MORRIS USA RECORDS MANAGEMENT MANUAL AND ANY AND ALL APPLICABLE DISPOSAL SUSPENSION NOTICES AND NONE OF THESE RECORDS ARE SUBJECT TO DISPOSAL SUSPENSION. S OM (2388 (RECORDS, COORDINATOR SIGNATURE) (DATE) — [las[gs (DATE) (DEPARTMENT MANAGER SIGNATURE) I CERTIFY THE RECORDS APPROVED FOR DISPOSAL HAVE BEEN DISPOSED. Thimra le Listhape A (3-95 (RECORDS MANAGEMENT DEPARTMENT SIGNATURE) (DATE) 9600807TS0z
Document type: Email

-----Original Message----- From: Cummings, Greg A. Sent: Wednesday, June 30, 1999 4:54 PM To: Crabill, Jean B.; Darden, Bennie C. Subject: FW: YSP/CR/NC 4-H Meeting [ will be out but | am OK with the visit. Greg V0922981202
Document type: Memo

: AS 4 SLtrillard 7 oo - MEMORANDUM oo July 28, 1977 e Mr. R.-E. Smith FROM: J. J. Giordano RE: NEWPORT. BRAND -- Lights Expansion Market Plan : Attached is a copy of subject plan for your information and comment. The overview includes all marketing aspects within the ‘currently established budget parameters. Should the brand re- - ‘ ceive the previously requested additional dollar support, Lights advertising and promotion, as well as parent NEWPORT advertising would be increased. Please advise should you have any questions or comments. JJG:hk - Attachment - cc: Messrs. Ave Bass a - ; - Cunningham — - - Flinn Giacoio - Gordon _ Keller Lawless Mastandrea Mueller Toti Ricci WGC (2) Hastings MCA
Document type: Email

2078702965 From: Liebengood, Howard Sent: Thursday, November 19, 1998 7:59 PM To: Scruggs, John . Subject: FW: Bring Visit It may be a roll of the dice but I would lean toward Charlie R. r/t Ryan. What think? Also might be good to have a real tax guy there, ie. Windburn.
Document type: Report

pecan anes seca nae ea : tia: Lisdithdbe soughesee Yorenapcesibia‘es cams’ “imecvention” scerosch iy Seconens industry to promote research on the effects of modified products on humen hesith. A Charitable trust, the Tobscco Products Research Trust. was set up to administer the Rented ten ten paiva condicared By the Commins ond ourzicn referees, thoes. - eerecearth see cra to tie Truss © henting. The to differentiate between effects of different tvpes of products. in wew of difficuines in establishing smoking histones adequatety in observational studies. and of the risk of bias when smokers switch to lower tar products as a result of developing symptoms. Thus the “core” study at St. Thomas's was developed on that basis. and delays in embarking on the research programme as a whole were due lergety to the need to approach this large-scale high-cost study very carefully, with the introduction of an additional “pre-pilot™ stage before the optimum design could be settied. and there were & number of unforeseen problems that had to be overcome. | The tar reduction component of the studies at St. Bartholomew's, and the tar retention work at Harwell also invoive intervention. but thére are fundamental difficulnes in extending this theorencaity desirable approach to the whole field of the T actrvines. Not only are costs per subject high. but ethical considerations de the intervention spproach in respect of some types of study (such as those concerned with effects in pregnancy). and it clearly cannot be used to examine slowty-developing conditions over periods of many years. Hence the Committee has approved several other epidemiqiogcial studies. mainty in the cardio-vascular field, thet are of Observational type. A need has aiso been seen for a number of experimental studies. to beern more of the croperties and behaviour of the smoke from modified products. In this, and in respect of other features, links have been established between a number of the studies funded by the Trust. The same representative cigarettes are, for example, included in the large epidemiological study (St. Thomas's), the human smoking - experimental work (Harwell) and the mutagenicity studies st Swansea. Information on 2 enstytical procedures is exchanged. and in some cases samples are cross-checked by Gitferent methods between the various centres. or sent to a central laboratory for _ ; assessment. Provision has aiso been made to poo! data from all the prospective mortality studies that the investigators are involved in, whether or not the basic funding is from the Trust. In these and other ways the Commnttee has attempted to develop an integrated programme. winch in the past year has been extended. following up some of the earlier pelot work and filling some gaps thst remasned on the scope of ms actiit.e1 ft @ hoped that some of the more recent expenmental studies funded will complement the esrker etedemiunlone al em Aae EL8O Lz8es
Document type: Letter

RY Renate ; Tobacco Company THOMAS J. STEICHEN Master Statistician Research & Development * Winston-Salem, NC 27102 910-741-4084 Fax: 910-741-1430 March 8, 1996 Dr. Geoffrey C. Kabat Department of Epidemiology and Social Medicine Albert Einstein College of Medicine Belfer Building Rm. 1302 1300 Morris Park Avenue Bronx, NY 10461-1601 Dear Dr, Kabat: I recently reviewed your paper, “Relation between exposure to environmental tobacco smoke and lung cancer in lifetime nonsmokers” (Kabat GC, Stellman SD, Wynder EL. Am. J. Epidemiol. 142(2):141-8, 1995), and noted a logical inconsistency that likely indicates a minor error. Specifically, in Table 2 (page 144), you list the odds ratios for males for exposure in childhood as 0.90 for “yes” (i.e., any exposure), 1.12 for “1 smoker in the household,” and 1.13 for “2+ smokers in the household.” These two later categories merely partition the “yes” category, therefore the OR for “yes” should be some weighted average of the OR’s for the sub-categories and should fall between 1.12 and 1.13. This is, unfortunately, not true in the published table, thus one or more of the OR must, I believe, be incorrect. I calculated crude OR’s and CI’s from your published case and control counts for each exposure category and was surprised to find that the crude results for “yes/no” identically replicated your published results. This was surprising because you indicated on page 142 that “[u}nconditional logistic regression was used to estimate the effect of exposure with adjustment for covariates, including age, education, and type of hospital.” Does Table 2 contain adjusted or crude results? Your paper does not clearly state if the results in Table 2 are, or are not, adjusted. My calculated crude results for “] smoker in the household” was 0.93 (95% CI: 0.42-2.06) and for “2+ smokers in the household” was 0.87 (95% CI: 0.31-2.45), These calculated crude sub-category results are logically consistent with the published, dichotomous “yes/no” results. e862 LSLTs wrk for smokers.”
Document type: Memo

R.J.Reynolds Tobacco International, Inc. Winston-Salem, N.C. 27102 H. G. Wick = r=) Vice President, Operations J F RJ RA December 4, 1986 MEMO TO: Mr. Richard Morgan Director, Quality Assurance SUBJECT: Lamina Particle Size We've had several questions about why we're looking for increased particle size in stemming and there has been some work done to illustrate that larger particle size improves filling power. My position has been that we're looking for a cleaner product in pneumatic separation to reduce stem particle “choke ups" in high speed machinery and that we're reducing the smaller scrap level of particle size which gener- ally equates to product waste in the end. From this, if we achieve a higher filling capacity with larger particle size, that's a bonus feature. Anyway, this discussion with our Research people in Canada produced some good discussions. , m / { ‘ HGW/ fb1 cc: Mr. L. C. Cook Mr. L. G. Hannemann Mr. C. E. Snyder Mr. R. E. Clements Mr. J. E. de Souza 8806 SS6O0sS
Document type: Report

rc a BRIGHT CONSUMER TRACKING AMONG BLACK SMOKERS EXECUTIVE SUMMARY BACKGROUND BRIGHT is an innovative low tar 85mm/100mm cigarette positioned primarily against menthol smokers. It is designed to deliver a unique new taste which is fresher during smoking and leaves a clean fresh aftertaste. BRIGHT entered test market in Michigan, Oklahoma, and Colorado on July 5, 1982. Pre-market research has suggested that Black menthol smokers represent a potential incremental share opportunity for the Brand. As a part of the test market research program developed for BRIGHT, the awareness, trial, purchase and repeat purchase levels for BRIGHT were tracked among Black menthol smokers in the Detroit Metro area. The acceptance and penetration levels of BRIGHT among these smokers should provide direction for possible modification of the Brand's national marketing plan. CONCLUSIONS Sampling was the most important source of initial brand awareness and trial for BRIGHT among Black smokers. Sampling may be particularly important in generating trial among Blacks in economically depressed areas. Trial was effectively converted into purchase of the Brand. By week fourteen, over one-half of all Black menthol smokers who had ever tried BRIGHT had also purchased it. Repeat purchase averaged 37% over the three tracking periods and appeared to be fairly stable over time. The appeal of the BRIGHT proposition was strongest among females, smokers aged 25-34, and those earning less than $15,000. BRIGHT's unique taste appeared to result in polarized perceptions among Black triers. The attributes most strongly liked were also most strongly disliked, which supports other research results. wil ns
Document type: Email

Cohen, Denise A. From: Cohen, Denise A. Sent: Tuesday, October 09, 2001 2:37 PM To: Suydam, Loraine Subject: RE: YSP Communications Dinner Patrick, Jen, Matt, Ankur, Marti, Helio Gonzales, Howard Benson, Martha Pfeffer. Denise Cohen Youth Smoking Prevention 917-663-3415 VILLPCLS 807
Document type: Report

‘REPORT FOR APRIL 1971 In the month of April 1971 cigaret taxes in the 50 states and the District of Columbia were imposed on 2,078,649,000 packages. This was an increase of 1.2% in the volume of cigarets taxed during the month of April 1970 when the package count was 2,053,715,000. Thirty-two jurisdictions showed increases and 19 showed decreases when the April 1971 package count was compared with April 1970. Cumulative figures on the volume of cigarets taxed for the ten month period July 1970 through April 1971 were up 3.9% from the corresponding months a year ago. The ten month total for the current fiscal year was 20,450,713,000 packages as against 19,685,623,000 packages for the corresponding period a year ago. Forty-three jurisdictions experienced increases and seven experienced decreases in the volume of cigarets taxed during the ten month period of the current fiscal year as against the corresponding period of the previous year. The aggregate of the cigaret taxes for April 1971 in the $1 juris- dictions was $226,471,308. 6/7/71 TIMS 0010084
Document type: Letter

THe COUNCIL FOR TOBACCO RESEARCH-U.S.A., INC: SUPPORTING BIOMEDICAL INVESTIGATION , 900 THIRD AVENUE . NEW YORK, NY 10022 (212) 421-8885 ARTHUR D. EISENBERG, PH.D. ASSOCIATE RESEARCH DIRECTOR April 5, 1993 Ms. Nancy Kwan | McGill University : Research Grants Office ; % Dawson Hall Room 416 85 Sherbrooke Street West Montreal, Quebec, Canada H3A2T6 Dear Ms. Kwan: Thank you for your interest in our program of research support. In response to your request, I am pleased to enclose a-copy of the explanatory materials sent by The Council for Tobacco Research to potential principal investigators who have inquired about support for their research projects. Those materials detail our two step application process. The executive committee of our Scientific Advisory Board first evaluates a Preliminary Application and decides whether or not to encourage submission of a Full Application. Their decision is based not only on scientific merit, but also on appropriateness for inclusion in one of the Council’s multidisciplinary program areas, as well as recognition of current support levels for similar projects. This procedure takes about two months. , In order that your office has on hand a reference set of our Full Application forms, a sample copy is enclosed. You will also find in this package our Statement of Policy, Information for Applicants and a recent Annual Report that lists currently supported grants and contains abstracts of papers that have appeared over the last year acknowledging support from The Council for Tobacco Research. If you have any further questions, please feel free to contact me. Sincerely, , Lo j u nT har Jaan tiry / Phat Arthur D. Eisenberg encl.
Document type: Email

2085697517 Daragan, Karen M. From: Daragan, Karen M. Sent: Sunday, February 11, 2001 3:21 PM To: Chaikin, Karen Subject: FW: Rules of Use Call Review i assume you will send to ginny...
Document type: Memo

ale yy RJR Interoffice Memorandum SUBJECT: R&D Perspective on DATE: November 19, 1987 Blind Product Test TO: W. M. Hildebolt FROM: M. F. Dube The results of a blind product test of fresh aftertaste (FAT) products were reported on 11/5/87. The management summary provided by MDD is included as an attachment. The products utilized the recently developed controlled release pellet technology with a low level of menthol. These products had measured smoke menthol deliveries of less than 6.5 ug/puff as compared to approx. 70 ug/puff for Salem Lt. and approx. 45 ug/puff for Newport. Three low menthol level products were tested, in which pellets containing 3%, 5% and 7% menthol by weight were inserted in the filter. No menthol was added via conventional means (i.e. top dressing, filter flavor). Products were tested among 18 - 49 year old non-menthol Full Flavor and Full Flavor Low Tar smokers, male and female. In the FF category, all three products were rated inferior on %70+ acceptance. All three products increased menthol, minty and artificial taste attributes. As we've seen repeatedly in qualitative work, FF non-menthol smokers will not accept a product if they can detect menthol. Further corroboration is provided by an earlier 1987 Concept/Product Test in which non-menthol smokers were given a concept, stating that "a hint of menthol" was used in the products. These products were overwhelmingly rejected. In the FFLT category, the 5% menthol product was rated parity among total category and superior among 18 - 24 year old smokers and among smokers with a high fresh aftertaste ideal. The 3% and 7% menthol products were rated inferior to the Control among FFLT products with the 3% level apparently too low and the 7% level too high. For the 5% product, tobacco taste, strength and harshness attributes were maintained while fresh aftertaste and cooling aftertaste were increased. Increases in mildness, menthol, minty and artificial taste were also noticed; however, this category did not view these attributes negatively as evidenced by the positive acceptance scores. These test results are highly encouraging in view of the fact that the suspected target category for a new product with fresh aftertaste is FFLT, young adult female smokers. Additionally, the 5% menthol pellet product was parity among category indicating that its performance was comparable to existing brands. However, it did have the aftertaste improvement vehicle which should enhance acceptance in the FFLT category. We expect to have a product with this technology on the market within the next 12 months. n iy (3s) oO N a 00 a S
Document type: Email

—--Original Message----- From: Schwartz, Linda H. Sent: Tuesday, Februat 05, 2002 10:34 AM To: Sampson, Steve F.; Roque, Veruchka; 'Phil McFarland’ Ce: Kleckner, ‘Amy (Leo Bumett}; Grant, Denny (Leo Burnett); Franklin, £.T, (Leo Burnett); Emily Gorman; Kerri Soukup; Kyle Wortham: Lee-anne Setterington; Manning, Mandy (Leo Bumett); Patrick Rynell Subject: RE: Quest for the West Phil - I'm not sure that I'll be here in the afternoon. Why the change? VOOSOLTS807
Document type: Letter

TEL. HARVARD UNIVERSITY SCHOOL OF PUBLIC HEALTH DEPARTMENT OF NUTRITION (617) 732- 665 HUNTINGTON AVENUE CABLE ADoRess: NUTHARV, BosTON BOSTON, MASGACHUSETTS O2118 December 28, 1981 Dr. David Stone The Council for Tobacco Research, Inc. 110 Fast 59th Street New York, New York 10022 Dear David, Please find enclosed the check-list of the items mailed to The Council for Tobacco Research for my renewal application. As indicated, these include the original and 8 copies of the signed application; original and 30 copies of Progress Report; original and 30 copies of separate Abstract of Progress Report; and 6 copies of six reprints and manuscripts. 1981 has been extremely productive and I am pleased with the excellent contribution of my colleagues. We are looking forward to a most exciting and productive year. I am most grateful for the support of The Council for Tobacco Research that made our progress possible. With warmest personal regards and best wishes for the New Year. Sincerely, Harry N. Antoniades, Ph.D. Professor of, Biochemistry sand “ Senior Investigator Center for Blood Research Enclosures HNA: gc 50144521
Document type: Letter

IJ Reynoliiss bacco Company WINS TrON-SALEM, N.C. January 14, 1954 Dear Fellow Employee: In order that you might have a better understanding of the many operations carried on within the Company, we have outlined in previous . letters the work performed by seven different Dupurimunts, Today we want to tell you about another important teammate, the Advertising Department. | This Department is under the management of Mr. W. T. Smither, a member of the Board of Directors of the Company. His Assistant is Mr. Ernest M. Fulp. The 20 employees in the Department are directly supervised by Mr. W. H. Maddrey, Office Manager, and Mr. Gray N. Leinbach, Assistant Office Manager. The operations of the Advertising Department lie along two general lines. First, this Department must keep in constant touch with every phase of your Company’s national advertising program—seeing that it follows plans made far in advance, verifying all invoices fox payment, and making sure the costs of the program stay within the advertising budget authorized, | | Second, it is the responsibility of this Department to prepare shipping instructions for all advertising and merchandising muted tals needed by the Company’s Sales Representatives in the field. National advertising of the Company’s products is one of the most DIC9 OZETE important phases of its business. It is true that superior quality is in itself the best advertisement for any product. But a sound and continued
Document type: Letter

oe. 28783 12:41 +++ TOBACCO INSTE DC LOS ANGELES HOSPITALITY COALITION clo Reed & Davidson 777 Figueroa Street, Suite 3400 Los Angeles, CA 90017 (213) 624-6200 June 29, 1993 Roger L. Mozingo R.J. Reynolds Tobacco Company 401 North Main Street Winston-Salem, NC 27102 Dear Roger. On behalf of the Los Angeles Hospitality Coalition, I want to thank you in ad- vance for your support of our efforts to qualify a referendum overturning the Los Angeles City smoking ban. If left unchallenged, the ban passed Jast week by the Los Angeles City Council would have a devastating impact on city restaurants, hotels and the entire Los An- geles hospitality industry. We hope that RJ. Reynolds Tobacco Company will make a contribution in the amount of $71,619.00. Please forward your check to the attention of Cary Davidson at 777 Figueroa Street, Suite 3400, Los Angeles, CA, 90017. As this effort is extremely time sensi- uve, please have your check or wire to our office or bank on July 1, 1993 if at all possible. Again, thank you for agreeing to help preserve a positive, competitive business climate for the Los Angeles city hospitality industry. Sincerely, a ee ae Lee Stitzenberger enclosure: Reed & Davidson 6/25/93 Memorandum bee: Bob MeAdam, Tabacco Institute Zo03/006 TI1657-0359
Document type: Letter

wo . ; - February 14, 1979 _ a TO: Ms, B. R. Garner . as ESS Re: SALEM LIGHTS Defensive Plan As you know, the Arctic Lights brand is scheduled to begin national advertising on March 26, 1979, Inasmuch as the Arctic Lights brand will not be introduced until late March, 1979, the SALEM LICHTS defensive effort should begin April, 1979. The result: would be to alter the national break of the Defensive Plan by one week in 120+ Market Importance groupings. Therefore, this requests that the national break of the SALEM LIGRTS Defensive Plan be the week of April 1 and not the week of March 26, 1979, Marketing Management has agreed with this start date. Please advise should you have any questions. blu by Cc. L. Sharp CLS:ac cc: Ms. S. A. MacKinnon , Mr. S. R. Strawsburg Mr. -D. J. Hopkins Sle EOnOS
Document type: Report

ITEMIZED FROJECT COSTS INCURRED FROM JUNE 11TH THROUGH SEPTEMBER S@TH. MACHINERY & TOOLING. i. 3 Units, Elevator Feeders. $45, AAA, 2a a Manufactured by FMC Corporation. . ee 1 Unit, @nd Reform Parts Feeder. $1e, SAA, we Ba Moorfeed Corporation. ‘3. 4 Units, Press Automat ion Systems. $14, 26M. we a. Are-Trel Manufacturing Co. 4e 1 Unit, ois Electric Fress Control System. $5, 291. a a. Universal Machine Ca. oe 1 Unit,O1S Press,Fergusen Indexing Unit #2. $2, 51. Ae a. Un mek Len Systems (Spare Unit). Be & Units, Moorfeed Convertors, 1Z@V ta 48aV. $1,643, aa a VMoorfeed Carporaticn. Te 3 Sections, Vibratory Part Feeder Infeed $695. aa Tracks, Feeder to Press. Ge H & K Tool ard Machine Ce. 8. if Units, Carbide Reform—-Ironing Die Secticns. $735. aa a. Froducticon Tool & Supply Ca. 9. 39 Units, Stainless Steel Wire Track Infeed $2, S21. aa Blecks. (Slet Punch Press) a H &€ K Tecl and Machine Ce. id. ea Units, Slet Punch & Die, Sine Key, Sine - $146.19 Locator Bars, & Slet Punch Locater Keys. @& Die Supply Co. aero, 1i. 126 Units, Asserted Die Springs. ; $460. Zz &. Lee Spring Ce. 7 1z. 1 Lot, 1/4" Clear Plastic Sheet. (Track Cevers) $41. 94 Ga Commercial Plastic Ca. is. # Units, 6 Gang Slet Furnch Dies © $9, 31a. aa. $18, 62a, aa & Danea Joon & Meld Co. 14. i Unit, 93 Gang Primes Shell Die. (#&) $22, 638. Wei a H & K Teal and Machine Co. ba n is. 1 Let, Shap Labar, Construction, Installation $1, 337.44 o ef Air Stripper Manifolds, Piping, and Die Debugging. 2 a 16. 1 Unit, Rework O18 Press Indexing Star. $495. A Ae H & K Tacl and Machine Co.
Document type: Resume

PRINCIPAL (NVESTIGATCAVPROGAAM DIRECTOR: CURRICULUM VITAE FAMILY NAME; Zhang GIVEN NAME: Zhi Xin DATE OF BIRTH: September 4, 1945 PLACE OF BIRTH: Shanghai, People's Republic of China CITIZENSHIP: Chinese MARITAL STATUS: Married EDUCATION: 1960-1963 Middle School affiliated to FuDan University 1963-1968 Department of Chemistry, FuDan University 1981-1986 Ph. D, Shanghai Institute of Cell Biology, Shanghai, China PROFESSIONAL EXPERIENCE: 1969-1973 Shanghai Chemical Factory, Technician 1974-1981 Laboratory of Chromatin Structure, Shanghai Institute of Cell Biology, Academia Sinica, Research Assistant in Biochemistry 1987-Pres Laboratory of Molecular Biology, Harvard School of Dental Medicine, Harvard Medical School, Postdoctoral Research Scientist PUBLICATIONS: Rui 1.Q., 8.D. Cheng, Z.X. Zhang, J.B. Gu. Isolation of DNA-dependent RNA polymerase from Ecoli X12. (1977) Biochemistry and Biophysics Sinica. 6: Wang J.L., 2.2. Zhang, Y.L. Wang, Q.L. Gao, L.Q. Hui. Reconstitution of calf thymus nucleohistone in vitro. (1977) Biochemistry and Biophysics Sinica. 5: 11-15, Qie R.L., Z.X. Zhang. The effect of chromatin non-histone Protein from calf thymus and rat liver on templet activation. (1978) Biochemistry and Biophysics Sinica. 2: 8-13, Eui L.Q., J.bL. Wang, 2Z.X. Zhang. Isolation and identification of calf thymus chromatin core particles by using Ultragel chromatography. (1979) J. Cell Biology Sinica. 24-26, Zhang Z.X., Q.L. Gao. Crystallization of nucleosome core particles from calf thymus. (unpublished). Zhang 2.X., Q.L. Gao, Progress in studies of nucleosome (review). (1980) J. Cell Biology Sinica. 2(€3): 1-6. Zhang Z.X. The evidence for Oxyrrhis marina chromatin nucleosome-like particles digested by micrococcal nuclease (summary), (1980) Acta PHS 398 (Rev. 985) Page 3. "Number Bayes comecutvety at the boriom tmraugnout te applicator. Do not ise suffoaes sun a0 fa, St
Document type: Email

——Original Messagea—— From: Hopkins Hadel, Linda L. Sent: Thursday, August 23, 2001 3:06 PM To: Levy, Carolyn J. Subject: Forgot to mention Carolyn, Given that we are continuing with the Parenting Teens Magazine, | now have no objection to leaving those references in the Parent Brochure. Prior to my giving Andrew that direction, just wanted fo be certain you and [ are on the same page. Linda Hadel Hopkins Youth Smoking Prevention 36 Es8Z8e7z1S80z
Document type: Letter

so \ Zt *. ca f> BROWN & WILLIAMSON TOBACCO CORPORATION iad West Mill Stovet +P 0. Box 35000-Lavierite, Kentucky 20292 January 16, 1978 Mr. T. R. Keniston 990 Forest St. Denver, CO 80220 Dear Mr. Keniston: ~- - _ a3 Thank you very much for your letter concerning our FACT advertising. We realize that the proper grammatical construction is "I smoke only . FACTS" but feel that it does not portray the proper conviction that ROCEMENT mere tpt at 2 685046443 PRODUC] ED FROM BEW W our copy line conveys. In order to personalize the choice of brand to the model being presented in the ad, we ‘auE- chosen the line “I'm realistic" and "I only smoke FACTS." a Os So a —s Since the subject of the advertisements is FACT cigarettes and only FACT cigarettes, it goes well beyond the connotation of the ad to imply that the only thing the model does is enjoy our brand of cigarettes. Our marketing research indicates that consumers reading this adver- tisement appear to receive exactly the intended connotation in the communication - that is, that the model portrayed has made an informed judgment on his brand of cigarettes and has chosen "to smoke only FACTS." Our feeling is that the American public has come to understand over the years that advertisements typically assume "poetic license" in order to convey their selling messages and further feel that they can make a dichotomy between advertising use of language and the exactly proper grammatical construction. Again, thank you for your letter and we hope that, if you are a smoker, you will try cur FACTS and see if you do not agree that they deliver atypically good taste for a low 'tar' cigarette. Sincerely, feos a” a” G. T. Reid Senior Brand Manager FACT Cigarettes GTR/te NOTICE IF THE FILM IMAGE IS LESS CLEAR a) 4 4 3. THAN THIS poitce, IT IS DUE TO THE OvALTTY ar Vers :
Document type: Letter

Averill A. Liebow, N.D. Professor and Chairman Department of Pathology School of Medicine University of California, San Diego La Jolla, California 92037 Dear Averili: _ Bnelosed 4s a check covering your expenses ant per diem in connection with the Scottsdale meeting. Z om sorry that you and your wife had the hotel Anoonvenience and trust 4t will never happen again. with all best wishes, Sincerely, W. T. Royt Executive Vice President WH ek enci.
Document type: Report

° July 26, 1968 me Dr. Murray Senkus SUTTON SMOKING MATERIAL In August 1967, personnel from the Sutton Research Corporation, Santa Monica, California displayed four sets of cigarettes to COMPANY personnel. One of these sets (70-mm. filler rod, no filter-tip) contained a non- tobacco filler, the socalled Sutton material. The other three sets (70-mm. filler rod plus 20-am. Estron filter tip) contained 1:3 tobacco blend:Sutton material, 3:1 tobacco blend:Sutton material, and the tobacco J blend alone. - A Sutton material cigarette on smoking burned much like a tobacco cigarette, gave an ash which behaved and looked much like tobacco cigarette ash, and produced smoke which had a very bland taste. This bland taste persisted even when the cigarette was smoked to a relatively short tutt length. Analysis of the Sutton material cigarette smoke indicated that it was as low as or lower than tobacco smoke in respect of the concentrations of those components considered harniful to the smoker by some authoritfes. The components of interest include nitrogen oxides, hydrogen cyanide, acetalde- hyde, acetone, acrolein, phenol, carbcn monoxide, and certain polycyclic hydrocarbons. “espite the fact that these analytical date were derived from —" a number of cigarettes much smaller than usual, the results were encouraging. After negotiation and signing of an agreement between the COMPANY and Sutton Research Corporation on December 6, 1967. Mr. T. S. Briskin, President of SRC, and Dr. Geoffrey Ward, consultant to SRC, described to COMPANY 8S9S 0S00S Seg gia ieee
Document type: Letter

THE UNIVERSITY OF TEXAS — MEDICAL BRANCH GALVESTON THE SCHOOL OF MEDICINE THE SCHOOL OF NURSING THE TECHNICAL CURRICULA THE POST-GRADUATE PROGRAM THE JOHN SEALY HOSPITAL THE CHILDREN’S HOSPITAL THE PSYCHOPATHIC HOSPITAL THE ROSA AND HENRY ZIEGLAR HOSPITAL 4 g lOctober 11, 1955 ¥ we was W, T. Hoyt, Executive Secretary Tobacco Industry Research Committee 5320 Empire State Building New York, New York. Dear Mr. Hoyt: As you may recall, you were kind enough to send me a copy of a picture of Dr. Hammond. We used it for an illustration, as you will see. Thank you for your cooperation. Yours truly, ™N Enc. R, H. Rigdon, MM. D. RHR ek Professor of Pathology