Document type: Report

RESEARCH AND DEVELOPMENT PROJECT STATUS REPORT “BATE: FERQ4 PROJECT NO.: B-448 PROJECT WANE: TOBACCO [ON CHROMATOGRAPHY {710} i PROJECT DESCRIPTION: Cisarette smcke anions and low solecular weight covalent solecules converted into anions will be analyzed. Analytes will be resolved hy IC, then detected electrachesically and by vacancy UV. Tons of interest are X0(2)-,NO(3)-,C1(-1, carboxylates, and covalent nolecules, NOx} SU(x) HEN,H(2}S,HCRO, and CHIZ)CHO. Collection aethods will be explored to expand analyte range and trapping reliability. Novel cigarette construction. encompassing blend, filler and filter additive effects, will be tested. Modifications will be correlated with ion orofiles, independent chemical analyses, and biological activity assays. Cation analyses will exgiore alkali groug,NH(4}+ and nicotinium ion cantributions ta new cigarettes. Transition aetal ion analyses will be pursued. If will continue to serve ether aroups. fons, such as CL{-),Br(~) HPOU4)=,NO(3)-,ND(2)-, and citrate, will be analyzed in tobacco grades, unsaoked cigarettes, fL, other production components and aatrices af savironmental iaport to aid in cigarette sodification, quality aenagement and process decision making. 2.00575 HOURS WAGES /OVERHEAD OTHER TOTAL CUMULATIVE NONTH BunéET = ACTUAL FUDGET = ACTUAL BUDGET = ACTUAL BUDGET = ACTUAL BUDBET = ACTUAL ee $ ef $ $ JAN 94 4g 30 4,100 4,154 fi Q 4,100 4,154 4,100 4,154 FEB 94 4g 7 4yild 3,075 9 t 4ité 3,875 8,216 74229 HAR 4 4B a 4,406 EG of] Q 4,400 a 42,622 7,229 APE 94 48 9 a7 8 CH] a 4,731 t 18,353 7,229 HAY 94 40 9 33 a 9 if 3,363 D) 19,716 7,229 JUN 94 4g 9 4,406 6 0 Q 4,404 @ 24,122 7,229 ah 94 48 4 4,326 4 g g 4,326 9 28,448 7,229 AUG 74 48 q 4 OBE 4 g 9 4,084 6 32,532 7,22? SEP 94 48 6 3,082 a 0 9 3,482 U 36,214 7,229 OCT 94 48 q 4,229 4 g U 4,229 9 40,443 7,229 NOY 94 4g ti 4,004 vy tf 9 4,004 q 44,447 7,229 DEC 94 36 i 2,683 9 6 o 2,083 4 47 130 7,229 TOTAL 30 87 47,130 7,229 0 a 47,130 7,229 LI. TECHNICAL APPROACH ESTIMATED ESTIMATED t COMPONENT TINE PERIOD HOURS COMPLETED i. Sacke trapping techniques GL/OAT94 - LRATL/EE 20 0 2. IC systea develoogent 4/04/94 - 12/51/94 90 ib | 3, Anion analyses G1/od/94 - 12/31/94 170 15 4, Cation analyses H1/04/94 - 12/51/98 156 15 §. Data correlations writing O1/O4 194 ~ LZUSE/ 84 _ 120 18 * TOTAL 550 VEL, HONTHLY ACTIVITY Anion orefile determinations af four separate samplings each of air dried vs. oven (79 deg C) - dripd RLT-4d filler composite 113.5 | lb scale-up) sheets completed. Overali, there apnears to be a random effect on anion levels in air vs. heat dried material, thus supporting reliability af further work with RLT-46. Tests on aunicioal tap water prompted by high pH (approximately 7.5-7.7): CL(-}, LL pagy ROG-, 1 ppag COG=, 2 opay S0C4=, 9 ppaz({l{-) being higher than normal], Apparentiy, the City water puaping | station adds hydrated lise (calcium hydrovidel to aisiaize lead and copper leacting from pipes. Analytical sugport for Life Sciences project on cellulose acetate breakdown by various enzymes and for Physical Chemistry on fabrics ongoing. New sheets : preparations, RLT-100 and -1G1, being tested for lowering BaP and autagenicity levels : SESETEES Florian Ferini mapeeed, PREPARED BY APPROVED