Document type: Resume

- Hsu, Ph.D. FE PRINCIPAL INVESTIGATOR/PROGAAM OIRECTOR: Th Chang i Ehad BIOGRAPHICAL SKETCH Give the fotiowing information for the key personnel and consultants listed on cage 2. Begtn with the Principal InvestigatoriProgram Director. Photocopy this page far each person NAME ~ | POSITION TITLE BIRTHDATE (Mo., Day, Yr) bi i Th-Chang Hsu \Associate Professor 8/3/38 EDUCATION (Begin with baccalaureate of oirer initial professional education. such as nursing. and :nciude Dostdoctoral training.) i : YEAA ] ore i ‘a INSTITUTION AND LOCATION i DEGREE CONFERRED | FIELD OF STUDY Kaohsiung Medical College i B.S. 1964 ! Pharmacy National Taiwan University i M.S. 1967 | Biochemistry University of Wisconsin i Ph.D. | 1972 | Biochemistry i i RESEARCH ANO PROFESSIONAL EXPERIENCE: Concluding with present position. list. in chronological order, previous employment, axpenence, and honors. Include present membership on any Federal Government public advisory committee. List, in chronological orger, the titles and com- plete raterences to ail publications dunng the past three years and to representative earer publications pertinent to this application. OO NOT XCEERGHESSTONAL EXPERTENCE: Research Assistant, Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, 1968-1972 Research Associate, Department of Pathology, University of Wisconsin, Madison, Wisconsin, 1972-1975 Research Fellow in Cancer Program, Oak Ridge National Laboratory, Biology Division, 1975-1977 Expert Investigator, Division of Cancer Cause and Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 1977-1981 Associate Professor, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, 1981-present Member, University of Maryland Cancer Center, University of Maryland Medical System, Baltimore, Maryland, 1984-present Visiting Scientist (IPA appointment), Laboratory of Human Carcinogenesis, NCI, NIH, Bethesda, Maryland, Jan 1988-June 1989 PUBLICATIONS: (selected from 50): Hsu, 1.C., Smalley, E.B., and Strong, F.M.: Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in diary cattle. Appl. Microbiol. 24: 683-690, 1972. Hsu, I.C., Van Miller, J.P., Seymour, J.L., and Allen, J.R.: Urinary metabolites of 2,5,2',5'-tetrachlorobiphenyl in the nonhuman primate. Proc. Soc. Exp. Biol, Med. 150: 185-188, 1975. Hsu, I.C., Robertson, K.A., and Allen, J.R.: Tissue distribution and binding properties of dehydroretronecine in the nonhuman primate. Chem. -Biol. Interactions 12: 19-28, 1976 Hsu, 1.C., and Yang, W.K.: DNA transfection of ecotropic murine leukemia viruses in mouse cell cultures. Cancer Res 37: 1709-1714, 1977 Hsu, I.C., Yang, W.K., Tennant, R.W., and Brown, A.: Transfection of FV-1 permissive and restrictive mouse cells with integrated DNA of murine leukemia viruses. Proc. Natl. Acad. Sci. USA 75: 1451-1455, 1978 Hsu, I.C., Stoner, G.D., Autrup, H., Trump, B.F., Selkirk, J.K., and Harris, C,C.: Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons. Proc. Natl. Acad. Sci. USA 75: 2003-2007, 1978 Harris, C.C., Hsu, 1.C., Stoner, G.D., Trump, B.F., and Selkirk, J.K.: Human pulmonary alveolar macrophages metabolize benzo(a)pyrene to proximate and ultimate mutagens. Nature 272: 633-634, 1978 Hsu, I.C., Harris, C.C., Trump, B.F., Schafer, P.W., and Yamaguchi, M.: Induction of ouabain resistant mutation and sister chromatoid exchanges in Chinese hamster cells with chemical carcinogenesis mediated by human pulmonary PHS 398 (Rev 10/88) Page qos FF “Number Cages consecutively al the Dottom tnraughou the acolication Oo 7of use sutfives Such as Sa 55 “50597708