Document type: Resume

tee PN tr Ca te Re ke BIOGRAPHICAL SKETCH Give the following information for the key personnel and consultants listed on page 2. Begin with the Principal Investigator/Pragram Director, Photocopy this page for each person. BIRTHDATE (Mo., Day, ¥r) POSITION TITLE Professor __ Biochemistry & Biophysics 12/27/46 EDUCATION (Begin with baccalaureate or other initlal professional education, such as nursing, and include postdoctoral training.) YEAR INSTITUTION AND LOCATION CONFERRED FIELO OF STUDY NAME TAS, Manjusri DEGREE Calcutta University India Christian Med. Coll., Vellore, India Albert Einstein Coll. Med., Bronx, NY Univ. of California, Los Angeles, CA RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, tIst, in chronological order, previous employment, experience, and honors. Include present membership on any Federal Government public advisory committee. List, in chronological order, the titles and com- plete references to all publications during the past three years and to representative earlier publications pertinent to this application. DO NOT EXCEED TWO PAGES. 1978-1984: Assistant Professor, University of Pennsylvania, Peas pbs PA 1984-1988: Associate Professor, University of Pennsylvania, Philadelphia, PA 1988-present: Professor, University of Pennsylvania, Philadelphia, P. Enzym. of Dipeptidase Angiotensin Conv. Enz. EGF-Receptor 1980-1984: Recipient of Research Career Development Award from NIH 1982-1986: Member of Cell Biology & Physiology Study Section, NIH 1982-present: Member of NIH site visit teams and special study sections 1988-1992: Member of NIH Reviewers Reserve ~ a a Selected Publications : *99, Bishayee, S., Feinman, J., Pitteriger, M., Michael, H., Das, M.: Cell surface insertion of exogenous EGF receptors into receptor minus mutant cells: Demonstration of insertion in the absence of added fusogenic agents. Proc, Natl. Acad. Sci. USA, 79: 1893-1897, 1982. 33. Das, M., Feinman, J., Pittenger, M., Michael, H., Bishayee, S.: Spontaneous transfer of exogenous EGF receptofs into receptor negative mutant cells. Methods Enzymol., vol. 98, 555-561, 1983. . . 36. Bishayee, S., Matesic, D., Das, M.: Identification of a 34,000 dalton mitogenic protein associated with plasma membranes from human A431 epidermoid carcinoma cells. Proc. Natl, Acad. Sci. USA, 81: 3399-3403, 1984. 37, Das, M., Knowles, B., Biswas, R., Bishayee, S.: Receptor modulating properties of an antibody directed against the EGF-receptor. Eur. J. Biochem., 141: 429-234, 1984, 38. Das, M., Biswas, R., Basu, M., Bishayee, S.: Mitogenic activity of the EGF-receptor after transfer from A431 carcinoma cells to receptor-negative fibroblastic cells. Cancer Res., 44; 3539-3545, 1984. *39 Basu, M., Biswas, R., Das, M.: 42,000 molecular weight EGF-receptor has protein kinase activity. Nautre (London) 311: 477-480, 1984. *40. Biswas, R., Basu, M., Sen-Majumdar, A., Das, M.: Intrapeptide autophosphorylation of the EGF-receptor: Regulation of kinase catalytic function by receptor dimerization. Biochemistry 24: 3795-3802, 1985. 41, Basu, M., Frick, K., Sen-Majumdar, S., Scher, C.D., Das, M.: EGF-receptor associated Seem activity is due to a M, 100,000 dissociable protein. Nature (London) 316: 640-641, d 4 eee oe PHS 398 (Rev. 10/88} Page ‘ “Number panes consecutively at the botiom ihreuchnut the agoslicatinn. Do set use suffixes such as Sa. Sh FF