Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer
Status: COMPLETED
Study type: INTERVENTIONAL
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|GENETIC: microarray analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Collaborators: Swedish Breast Cancer Group|Swiss Group for Clinical Cancer Research|Anglo Celtic Cooperative Oncology Group