Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.
Status: RECRUITING
Study type: INTERVENTIONAL
Conditions: Breast Cancer
Interventions: OTHER: Main study:|OTHER: Sub-study:
Sponsor: Institut Claudius Regaud
Collaborators: Artios Pharma Ltd