Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis
Status: NOT_YET_RECRUITING
Study type: INTERVENTIONAL
Conditions: Breast Carcinoma|Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Neoplasm in the Leptomeninges
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|PROCEDURE: Resection|DRUG: Trotabresib|DRUG: Vinorelbine
Sponsor: Northwestern University
Collaborators: National Cancer Institute (NCI)