CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
Status: RECRUITING
Study type: INTERVENTIONAL
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Invasive Breast Carcinoma|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions: DRUG: Docetaxel|PROCEDURE: Lumpectomy|PROCEDURE: Mastectomy|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|BIOLOGICAL: Pertuzumab|RADIATION: Radiation Therapy|BIOLOGICAL: Trastuzumab|BIOLOGICAL: Trastuzumab Emtansine
Sponsor: ECOG-ACRIN Cancer Research Group
Collaborators: National Cancer Institute (NCI)