Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer
Status: TERMINATED
Study type: INTERVENTIONAL
Conditions: Breast Cancer|Cancer of Breast|Breast Carcinoma
Interventions: DRUG: Palbociclib|DRUG: Letrozole|BIOLOGICAL: Trastuzumab|DRUG: Goserelin|PROCEDURE: Breast surgery|PROCEDURE: Research tumor biopsy|PROCEDURE: Research bone marrow (OPTIONAL)|PROCEDURE: Research blood sample|GENETIC: Research blood for germline DNA|PROCEDURE: Blood for detection of circulating tumor cells
Sponsor: Washington University School of Medicine
Collaborators: Pfizer|Rising Tide Foundation