Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer
Status: TERMINATED
Study type: INTERVENTIONAL
Conditions: Cardiac Toxicity|Inflammatory Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|DRUG: paclitaxel|BIOLOGICAL: trastuzumab|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy|DRUG: tamoxifen citrate|OTHER: laboratory biomarker analysis
Sponsor: National Cancer Institute (NCI)