Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Status: ACTIVE_NOT_RECRUITING
Study type: INTERVENTIONAL
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Breast Adenocarcinoma|HER2/Neu Negative|Locally Advanced Breast Carcinoma|Metastatic Breast Carcinoma|Recurrent Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Entinostat|DRUG: Exemestane|DRUG: Goserelin|DRUG: Goserelin Acetate|PROCEDURE: Magnetic Resonance Imaging|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment
Sponsor: National Cancer Institute (NCI)