Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations
Status: ACTIVE_NOT_RECRUITING
Study type: INTERVENTIONAL
Conditions: Deleterious BARD1 Gene Mutation|Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|Deleterious BRIP1 Gene Mutation|Deleterious EPCAM Gene Mutation|Deleterious MLH1 Gene Mutation|Deleterious MSH2 Gene Mutation|Deleterious MSH6 Gene Mutation|Deleterious PALB2 Gene Mutation|Deleterious PMS2 Gene Mutation|Deleterious RAD51C Gene Mutation|Deleterious RAD51D Gene Mutation|Hereditary Breast and Ovarian Cancer Syndrome|Premenopausal
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Oophorectomy|OTHER: Quality-of-Life Assessment|PROCEDURE: Salpingectomy|PROCEDURE: Salpingo-Oophorectomy
Sponsor: M.D. Anderson Cancer Center
Collaborators: National Cancer Institute (NCI)