Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Study type: INTERVENTIONAL
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Locally Advanced Breast Carcinoma|Locally Advanced HER2-Negative Breast Carcinoma|Metastatic Breast Carcinoma|Metastatic HER2-Negative Breast Carcinoma|Unresectable Breast Carcinoma|Unresectable HER2-Negative Breast Carcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|PROCEDURE: X-Ray Imaging
Sponsor: National Cancer Institute (NCI)