Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery
Status: COMPLETED
Study type: INTERVENTIONAL
Conditions: Estrogen Receptor-negative Breast Cancer|Estrogen Receptor-positive Breast Cancer|HER2-positive Breast Cancer|Progesterone Receptor-negative Breast Cancer|Progesterone Receptor-positive Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|DRUG: paclitaxel|BIOLOGICAL: filgrastim|DRUG: capecitabine|DRUG: methotrexate|DRUG: vinorelbine tartrate|PROCEDURE: needle biopsy|PROCEDURE: therapeutic conventional surgery|OTHER: immunohistochemistry staining method|BIOLOGICAL: trastuzumab|DRUG: tamoxifen citrate|DRUG: letrozole|OTHER: laboratory biomarker analysis
Sponsor: University of Washington
Collaborators: National Cancer Institute (NCI)