Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
Status: ACTIVE_NOT_RECRUITING
Study type: INTERVENTIONAL
Conditions: Breast Adenocarcinoma|Hormone Receptor Positive|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIIB Breast Cancer AJCC v7
Interventions: DRUG: Anastrozole|DRUG: Exemestane|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Tamoxifen Citrate
Sponsor: National Cancer Institute (NCI)
Collaborators: American College of Surgeons|Cancer and Leukemia Group B|NSABP Foundation Inc|NCIC Clinical Trials Group|North Central Cancer Treatment Group|SWOG Cancer Research Network