Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
Status: ACTIVE_NOT_RECRUITING
Study type: INTERVENTIONAL
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer
Interventions: BIOLOGICAL: therapeutic estradiol|DRUG: deslorelin|DRUG: therapeutic testosterone|PROCEDURE: therapeutic conventional surgery|OTHER: active surveillance|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Sponsor: City of Hope Medical Center
Collaborators: National Cancer Institute (NCI)