HERBAL COMPOSITIONS FOR ITCHY OR INFECTED SKIN

Abstract: The present invention relates to the preparation and use of compositions for the treatment of skin disorders itchy and/or infected skin such as impetigo, acne (on face, forehead scalp and on the back of the body) and fungal infection of skin and nails. Whether the infection may be acute or chronic or sub-acute or acute on chronic. As well as for the promotion of non carrier state of the human beings and animals from some pathogenic bacteria such as staphylococci. The compositions are based on extracts from the plants <i>Cassia tora, Centratherum anthelminticum and/or Melia</i> azadirachta. A variety of other herbal extracts may be included and the composition may take the form of a freeze dried or a spray dried powder or presence of this in a cream or ointment based on Ghee, or in a cream or ointment form developed with any other vehicle, or they may be in a powdered form without spray drying. That spray dried or freeze dried powder may be suspended in a suitable mouth wash or nasal drops. The herbs may be in a powdered form of suitable for preparing decoctions in hot water. Laboratory results are of Specimen Example 2. Specimen Example 1 I have found working on the patients clinically as broad spectrum covering pustules as well as fungal infections.

Description: HERBAL COMPOSITIONS for Itchy or infected skin BACKGROUND OF THE INVENTION This invention relates to the manufacture and use of herbal compositions for the treatment of various skin disorders itchy or infected skin such as impetigo, acne (on face, forehead scalp and on the back of the body) and fungal infection of skin and nails. Acne Acne is a disease of the pilosebaceous unit. It predominantly affects the face, back and chest. Perioral area of the face is more vulnerable. Still acne is not a simple face skin disorder, few patients with severe acne on the back or chest who have non on the face. Acne is a mixture of, inflammation- infection process and favoured by the presence of time oriented hormonal imbalance. Most commonly found anaerobes and/or aerobe- bacteria in the acne are Staphylococcus albus, Staphylococcus epider idis , Pi tirosporum ovale Propionaebacterium acnes . One gentleman suffering from acne on his face and also on his back for years. He was reluctant for antibiotics because he knew that antibiotics gave more trouble. He came to me for natural treatment for keloids he was suffering for long time. I gave him oral compound and herbal cream to apply one month supply, on 25th day of treatment he came to me for cream supply. At that time I counted spots on his back out of 33 spots 25 spots were healed. I realised that this is Propionae bacterium has disappeared. Now I would like to present a laboratory proof here. Types of the lesions Comedones are of two types. Open (black heads), closed (whiteheads) Open blackheads contain greyish greasy content of the pilosebaceous duct which is affected by acne process . Some blackheads develop into inflamed lesions . Closed comedones (whiteheads) are caused by a distension of the pilosebaceous duct and these are more likely than open comedones (blackheads) to develop into inflamed lesions . About a quarter of closed comedones spontaneously resolve within 3-4 days while the majority progress to become inflamed. Some whiteheads persist in a latent state for months. Facial scarring Acne and immune response As previously stated acne is a mixture of, inflamination- infection process and favoured by the presence of time oriented hormonal imbalance . Pustules resolve faster than papules. In pustules natural healing process is faster because of polymorphonucleocyte activity and in papules the natural healing process is slower because here it depends on lymphocyte activity. Here this lymphocyte activity remains helpful in further growth of the comedones . Macules are the end result of inflamed lesions, most persist for 7 days and they can linger for several weeks . Present invention is useful for prevention of further scarring. Facial scarring It is well recognised that facial scarring and scars on the back are associated with long standing changing guards-games played by different sorts of bacteria fungi and immune response of the body in the form of production and presentation of lymphocyte and polymorphonucleocytes . Fungal nail infection and immune response The skin in some people react to external and internal changes very fast such as drinking alcohol, washing with alkaline soap, increased sweating in summer and more humid skin environment . All these skin sensitising factors could bring circulatory changes on the skin and inside the nail beds . It is well recognised that alkalinity on the skin initiates or promotes fungal infections . In long journey of antibiotics, resistance development and hide and seek games played by organisms the present invention remains most blissful. The skin and blood purifier herbal composition for oral and topical treatments for Acne and fungal infections of skin and the nails Oral composition Centratherum anthelminticu , Curcuma longa, Melia azardirachta, Picrorrhyza curroa, Cassia tora, Comiphora mukul , Ni thenia somnifera, Tinospora cordi folia, Asparagus racemosus, Triphala . Topical treatment Centratherum anthelminticum, Melia azadirachta, Cassia tora . Mouth wash Centratherum anthelminticum, Melia azadirachta, Cassia tora Face wash and body wash Centrat-πerum anthelminticum, Melia azadirachta, Cassia tora Nasal drops Centra t-ierum anti.el_πinticu_n, Melia azadirachta, Cassia tora SUMMARY OF THE INVENTION According to a first aspect of the present invention, there is provided a composition for use in the treatment of skin disorders itchy or infected skin such as impetigo, acne (on face, forehead scalp and on the back of the body) and fungal infection of skin and nails, which composition comprises extracts derived from the seeds of the plant Centratherum anthelminthicum. According to second aspect of the present invention, there is provided a composition for use in the treatment of skin disorders such as acne and /or fungal infection and/ or fungal infections of the nails, which composition comprises extracts derived from the seeds of the plant Centratherum anthelminthicum fruit-oil and extract from leaves, bark, roots of the plant Melia azadirachta . According to third aspect of the present invention, there is provided a composition for use in the treatment of skin disorders such as acne and /or fungal infection and/ or fungal infections of the nails, which composition comprises extracts derived from the seeds of the plant Centratherum anthelminthicum fruit-oil and extract from leaves, bark, roots of the plant Melia azadirachta and extracts derived from the seeds of the plant Cassia tora . According to fourth aspect of the present invention, there is provided a composition for use in the treatment of skin disorders such as acne and /or fungal infection and/ or fungal infections of the nails, which composition comprises extracts derived from at least one member of the group consisting of the plants Centratherum anthelminticum, Melia azardirachta, Cassia tora which further comprises extracts derived from Picrorrhyza curroa, Comiphora mukul , Withenia somnifera, Tinospora cordi folia, Asparagus racemosus, Triphala . According to fifth aspect of the present invention, there is provided a method of treating itchy skin or infected skin through the administration of extracts derived from at least one member of the group consisting of the plants Centratherum anthelminticum, Melia azadirachta, Cassia tora . According to a sixth aspect of the present invention, there is provided a method of treating itchy and infected skin through the administration of extracts derived from at least one member of the group consisting of the plants Centratherum anthelminticum, Melia azadirachta, Cassia tora and further extracts derived from at least one member of the group consisting of the plants Picrorrhyza curroa, Comiphora mukul , Wi thenia somnifera, Tinospora cordifolia, Asparagus racemosus, Triphala . According to a seventh aspect of the present invention, there is provided a method of treating infected skin through the administration of extracts derived from at least one member of the group consisting of the plants Centratherum anthelminti cum, Melia azadirachta, Cassia tora . According to an eighth aspect of the present invention, there is provided a method of treating acne and fungal infections of skin and the nails through the administration of extracts derived from at least one member of the group consisting of the plants Centratherum anthelminticum, Melia azadirachta , Cassia tora and further extracts derived from at least one member of the group consisting of the plants Picrorrhyza curroa, Comiphora mukul , Wi thenia somnifera, Tinospora cordifolia, Asparagus racemosus, Triphala . The composition of the present invention may be dispersed in a suitable carrier for topical application as a cream, gel, ointment or lotion, or may be in the form of a dry powder, or other form suitable for a portable decoction, for example by way of a tea bag. Alternatively, the composition may be formulated in a tablet form, or composition may be formulated and made spray dried extract . Preferably, the composition spray dried extract is dispersed in a carrier suitable for topical application comprising ghee, which is clarified butter. The compositions of the present invention help to break the cycles of pruritus-inflamation-pruritus, and of infection-inflamation-pruritus , thereby promoting faster healing of acute, sub-acute and chronic bacterial and fungal infection of the skin and fungal of nails . The compositions of the present invention are additionally useful in reducing the effects of stress and reinforcing immune response . Extracts from Centratherum anthelminticum, Melia azadirachta disperse in a sesame oil and cream was formulated with ghee and antimicrobial preservative efficacy test was performed using Propionihacterium acnes NCTC 737 was introduced in a cream Inoculum count cfu/ml 2.1 x 10 5 and significant results were seen logarithm reduction unto 5.32 was achieved at the 7 days inoculation test and 14 days inoculation tests . Extract from Cassia tora dispersed well with yogurt and heated and then applied on impetigo worked well . the activity was dose dependent . Example 1 A preferred embodiment of the present invention is a cream made up as follows : Ghee 3kg Water boiled and cooled freezing temperature 31itres Freeze dried extract of Centra therum anthelminticum 5 gms (2 kilogram raw material of of the seeds provided 100 grams of freeze dried powder) . Medicated Sesame oil 500 ml (500 ml sesame oil treated with Centratherum anthelminticum seeds lOOgm, Rose petals lOOgm, Melia azadirachta leaves 100 gm, Cassia tora seeds 50 gm and some water to make a paste} . To make up the cream, the ghee is first hydrolysed in a clean stainless steel vessel with three litres of water (boiled and cooled freezing ) then add 500 ml of medicated oil. Example 2 A preferred embodiment of the present invention is a cream made up as follows : Ghee 3kg Water boiled and cooled freezing temperature 31itres Freeze dried extract of Centratherum anthelminticum 5 gms (2 kilogram raw material of of the seeds provided 100 grams of freeze dried powder__ Medicated Sesame oil 500 ml (500 ml sesame oil treated with Centratherum anthelminticum seeds lOOgm, Rose petals lOOgm, Melia azadirachta leaves 100 gm, and some water to make a paste) . To make up the cream, the ghee is first hydrolysed in a clean stainless steel vessel with three litres of water (boiled and cooled freezing ) then add 500 ml of medicated oil .

Claims: Claims Amendments to the claims have been filed as follows 1. The use in the manufacture of a medicament for the treatment of impetigo, acne and fungal infections of the skin and nails of an extract from seeds of the plant Centratherum anthelminticum. 2. The use in the manufacture of claim 1, together with said extract, of fruit oil and an extract derived from a part of the plant Melia azadirachta . 3. The use according to claim 2, wherein the Melia azadirachta extract is derived from leaves, bark or roots of the plant Melia azadirachta . 4. The use according to any preceding claim, wherein, included in the medicament, is an extract derived from seeds of the plant Cassia tora . 5. The use according to any preceding claim, wherein, included in the medicament, is one or more further extracts, the or each further extract being derived from Pi crorrhi za kurroa . Co i hora mukul , Wi thenia somnifera . Tinospora cordifolia . AsparaQus racemosus and Triphala. 6. A pharmaceutical composition for use in the treatment of skin disorders and fungal infections of the skin and nails, which comprises herbal extracts derived from Centratherum anthelminticum and Cassia tora, the herbal extracts being dispersed in a suitable carrier for topical application or being in the form of a dry powder for the preparation of a potable decoction, a mouthwash or nasal drops . 7. A composition as claimed in claim 6, which additionally contains a herbal extract derived from Melia azadirachta . 8. A composition according to claim 6 to 7, which additionally comprises a herbal extract derived from one or more of pi crorrhvza curroa , Comiphora mukul , Wi thenia somnifera , Tinospora cordifolia , Aspara rus racemosus and Triphala . 9. A pharmaceutical composition for use in the treatment of skin disorders and fungal infections of skin and nails, which comprises the herbal extracts derived from Centratherum anthelminticum, Melia azadirachta and one or more of Comiphora mukul , Wi thenia somnifera and Triphala . the herbal extracts being dispersed in a suitable carrier for topical application or being in the form of a dry powder for the preparation of a potable decoction, a mouthwash or nasal drops. 10. A composition as claims in any claims 6 to 9 in which the powder is a spray dried or freeze dried powder or is for topical application and includes Ghee as carrier .

Inventors: SHAH ELADEVI, SHAH, ELADEVI
Applicants: SHAH ELADEVI, SHAH, ELADEVI
Application year: 2000
Main classification: A61K35
IPC codes: A61K36, A61P17, A61P31