COSMETIC COMPOSITIONS CONTAINING VITAMIN B3

Abstract: Disclosed are cosmetic compositions including lipsticks, comprising from about 0.01 % to about 50 % by weight, of a crystalline vitamin B3 compound having an average particle size of from about 0.01 mu m to about 200 mu m; from about 1 % to about 90 %, b y weight, of an emollient component; and from about 1 % to about 90 % by weight, of a solidifying agent. The compositions provide improved skin feel of crystalline vitamin B3 compounds when applied to skin.

Description: COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 FIELD OF THE INVENTION The present invention relates to topical cosmetic compositions containing crystalline vitamin B compounds dispersed m an emollient or oil phase BACKGROUND OF THE INVENTION Niacm, also known as vitamin B 3 , is the common name for nicotrnic acid The physiologically active form of niacm is macmamide. also a member of the vitamin B 3 family of compounds Niacm and macmamide (nicot ic acid amide) function in the body as components of two coenzymes nicotmamide adenme dinucleotide (NAD) and nicotmamide adenine dinucleotide phosphate (NADP) Until recently, these vitamin B 3 compounds were used exclusively to treat niacin deficiency and pellegra Today, however, solubilized vitamin B 3 compounds have also found use m the area of skm care actives Bπtish Patent 1,370,236 describes compositions for skm lightening containing 0 5% to 10% niacin Similarly, U S Patent 4,096.240 discloses the use of 0 1% to 10% macmamide for skm lightening Vitamin B 3 compounds have also been found useful m regulating the texture of human skm See PCT application WO 97/39733, to Oblong et al However, when applied to the skm in crystalline form (l e , powder), vitamin B 3 compounds tend to impart a rough feel to the skin In the past, the crystalline vitamin B 3 compounds were solubilized in a polar solvent before application to skm, thus alleviating the rough feel of the crystals However, solubilization reduced the efficacy of the vitamin B compound upon contact with the skm Thus there exists a need for cosmetic compositions comprising unsolubilized crystalline vitamin B 3 compound(s) which provide improved consumer perceived sk feel The present inventors have discovered that cosmetic formulations incorporating the crystalline vitamin B 3 compounds of specific particle size m combmation with an emollient, improve the consumer perceived feel of the crystalline vitamin B 3 compound on the skin The present inventors have further discovered that these compositions are especially useful to impart vitamin B 3 benefits to the lips with improved skm feel when used in lipstick compositions including a solidifying agent It is, therefore, an aspect of the present invention to provide cosmetic compositions, preferably anhydrous cosmetic compositions, comprising crystalline vitamin B 3 compounds which improve the appearance and feel of the skin while alleviating the rough feel of the crystalline vitamin B 3 compound Another aspect of the present invention is to provide cosmetic compositions compπsmg crystalline vitamin B 3 compounds havmg reduced particle size A further aspect of the present invention is to provide substantially anhydrous lip compositions such as lipsticks and lip-paints, compπsmg crystalline vitamin B 3 compounds havmg reduced particle size These and other aspects will become readily apparent from the detailed descπption which follows SUMMARY OF THE INVENTION The present mvention relates to cosmetic compositions providing improved skm feel, which contain from about 001% to about 50%, by weight, of a crystalline vitamin B 3 compound havmg an average particle size of from about 0 Olμm to about 200μm, from about 1% to about 90%, by weight, of an emollient component, and from about 1% to about 90%, by weight, of a solidifying agent The compositions of the present invention are useful for improving consumer perceived skm feel of crystalline vitamin B 3 compounds when applied to the skm All percentages, parts and ratios are based upon the total weight of the cosmetic compositions of the present mvention, unless otherwise specified All such weights as they pertam to listed mgredients are based on the active level and, therefore, do not include earners or by-products that may be mcluded in commercially available matenals, unless otherwise specified DETAILED DESCRIPTION OF THE INVENTION As used herein, the term "cosmetics" mcludes make-up, foundation, and skin care products The term "make-up" refers to products that leave color on the face, including foundation, blacks and browns, l e , mascara, concealers, eye lmers, brow colors, eye shadows, blushers, lip colors, and so forth Skin care products are those used to treat or care for, or somehow moisturize, improve, or clean the skm Products contemplated by the phrase "skm care products" mclude, but are not limited to, adhesives, bandages, toothpaste, anhydrous occlusive moisturizers, antiperspirants, deodorants, powder laundry detergent, fabnc softener towels, occlusive drug delivery patches, nail polish, powders, tissues, wipes, solid emulsion compact, hair conditioners-anhydrous and the like The term "foundation" refers to liquid, creme, mousse, pancake, compact, concealer or like product created or remtroduced by cosmetic companies to even out the overall coloring of the skin Foundation is manufactured to work better over moisturized and or oiled skm As used herem the term "compnsing" means that the composition can contain other ingredients which are compatible with the composition and which preferably do not substantially disrupt the compositions of the present mvention The term encompasses the terms "consisting of and "consisting essentially of ESSENTIAL COMPONENTS Vitamin B Compound The compositions of the present mvention compnse a safe and effective amount of a natural or synthetic vitamin B3 compound in crystalline form The compositions of the present mvention preferably comprise from above 0 01% to about 50%, more preferably from about 0 1% to about 30%, even more preferably 0 5% to about 20%, most preferably from about 1% to about 10% of the vitamin B3 compound As used herem, "vitamin B3 compound" means a compound havmg the formula wherem R is - CONH2 (1 e , macmamide), - COOH (1 e , nicotmic acid) or - CH2OH (1 e , mcotmyl alcohol), derivatives of macmamide, nicotmic acid, and/or nicotmyl alcohol, and salts of any of the foregomg Exemplary derivatives of the foregomg vitamin B3 compounds include nicotmic acid esters, mcludmg non-vasodilatmg esters of nicotmic acid, mcotmyl ammo acids, and nicotmyl alcohol esters of carboxylic acids Suitable esters of nicotinic acid include mcotinic acid esters of C1 -C22, preferably Ci -Ci g, more preferably C1 -C5 alcohols The alcohols are suitably straight-chain or branched chain, cyclic or acyclic, saturated or unsaturated (mcludmg aromatic), and substituted or unsubstituted The esters are preferably non-rubifacient As used herein, "non-rubifacient" means that the ester does not commonly yield a visible flushing response after application to the skm m the subject compositions (the majority of the general population would not experience a visible flushing response, although such compounds may cause vasodilation not visible to the naked eye) Alternatively, a mcotimc acid matenal which is rubifacient at higher doses could be used at a lower dose to reduce the rubifacient effect Non-rubifacient esters of nicotinic acid mclude tocopherol nicotinate and inositol hexamcotmate, tocopherol mcotmate is preferred Other denvatives of the vitamin B3 compound are denvatives of macmamide resulting from substimtion of one or more of the amide group hydrogens Nonlimitmg examples of derivatives of macmamide useful herem include mcotmyl ammo acids, denved, for example, from the reaction of an activated nicotmic acid compound (e g , nicotinic acid azide or nicotmyl chlonde) with an ammo acid, and mcotmyl alcohol esters of orgamc carboxylic acids (e g , Cl - C18) Specific examples of such denvatives mclude nicotinunc acid and nicotmyl hydroxamic acid, which have the following chemical structures nicotinuπc acid mcotmyl hydroxamic acid Exemplary mcotmyl alcohol esters include nicotmyl alcohol esters of the carboxylic acids salicylic acid, acetic acid, glycohc acid, palmitic acid and the like Other non-limiting examples of vitamm B3 compounds useful herem are 2-chloronιcotιnamιde, 6-amιnonιcotmamιde, 6-methylnιcotιnamιde, n-methyl- mcotmamide, n,n-dιethylmcotmamιde, n-(hydroxymethyl)-nιcotιnamιde, qumolmic acid lmide, mcotmani de, n-benzylnicotinamide, n-ethylnicotmamide, mfenazone, mcotmaldehyde, lsonicotmic acid, methyl lsonicotmic acid, thiomcotinamide, nialamide, l-(3-pyndylmethyl) urea, 2-mercaptomcotιnιc acid, mcomol, and niaprazine Examples of the above vitamin B3 compounds are well known m the art and are commercially available from a number of sources, e.g., the Sigma Chemical Company (St Louis, MO); ICN Biomedicals, Inc. (Irvm, CA) and Aldrich Chemical Company (Milwaukee, WI) One or more vitamm B3 compounds may be used herein. Preferred vitamm B3 compounds are macmamide and tocopherol nicotmate. Niacinamide is more preferred. Salts of the vitamin B3 compound are also useful herein Nonlimiting examples of salts of the vitamm B3 compound useful herem include orgamc or inorganic salts, such as inorgamc salts with anionic inorganic species (e g., chlonde, bromide, iodide, carbonate, preferably chlonde), and organic carboxylic acid salts (including mono-, di- and tri- Cl - C18 carboxylic acid salts, e.g., acetate, sa cylate, glycolate, lactate, malate, citrate, preferably monocarboxylic acid salts such as acetate). These and other salts of the vitamin B3 compound can be readily prepared by the skilled artisan, for example, as described by W. Wenner, "The Reaction of L-Ascorbic and D-Isoascorbic Acid with Nicotmic Acid and Its Amide", J. Orgamc Chemistry, VOL. 14, 22-26 (1949), which is incorporated herem by reference. Wenner descnbes the synthesis of the ascorbic acid salt of macmamide. When used, salts, derivatives, and salt denvatives of macmamide are preferably those havmg substantially the same efficacy as macmamide in the methods of regulatmg skm condition descnbed herein. In a preferred embodiment, the vitamm B3 compound contains a limited amount of the salt form and is more preferably substantially free of salts of a vitamm B3 compound. As used herein, "substantially free of salts" means that by weight, less than 50% of the vitamm B 3 compounds m the composition are m salt form. Preferably the vitamm B3 compound contams less than about 20% of such salt, and is more preferably essentially free of the salt form. In a preferred embodiment, the ring nitrogen of the vitamm B3 compound is substantially chemically free (e.g., unbound and/or unhindered), or after delivery to the skm becomes substantially chemically free ("chemically free" is hereinafter alternatively referred to as "uncomplexed") More preferably, the vitamin B3 compound is essentially uncomplexed Therefore, if the composition contains the vitamm B3 compound m a salt or otherwise complexed form, such complex is preferably substantially reversible, more preferably essentially reversible, upon delivery of the composition to the skm For example, such complex should be substantially reversible at a pH of from about 5 0 to about 6 0 Such reversibility can be readily determined by one havmg ordinary skill in the art More preferably the vitamin B3 compound is substantially uncomplexed in the composition prior to delivery to the skm Exemplary approaches to minimizing or preventing the formation of undesirable complexes include omission of materials which form substantially irreversible or other complexes with the vitamm B3 compound, pH adjustment, ionic strength adjustment, the use of surfactants, and formulating wherein the vitamin B3 compound and materials which complex therewith are in different phases Such approaches are well within the level of ordinary skill m the art The vitamm B3 compound may be included as the substantially pure matenal, or as an extract obtained by suitable physical and/or chemical isolation from natural (e g , plant) sources The vitamin B3 compound is preferably substantially pure, more preferably essentially pure The vitamm B 3 compounds of the present mvention have an average particle size of from about 0 Olμm (microns) to about 200μm, preferably from about 0 Olμm to about lOOμm, more preferably from about 0 Olμm to about 50μm, most preferably from about 0 Olμm to about 20μm Preferably, the vitamm B 3 compounds have a particle size distnbution such that at least about 60% of the vitamm B 3 particles are less than about 30μm, more preferably at least about 75% of the vitamm B 3 particles are less than about 30μm, most preferably at least about 85% of the vitamm B 3 particles are less than about 30μm, still more preferably at least about 90% of the vitamin B 3 particles are less than about 30μm Emollient The compositions of the present mvention further compnse an emollient suitable for suspending or otherwise dispersmg the crystalline vitamm B 3 compound therem Any emollient that is known or otherwise suitable for use in cosmetic applications, and which is also compatible with the crystalline vitamin B 3 compound in the composition, may be used m the composition of the present mvention Preferred emollients for use in the composition of the present mvention are those matenals refened to in the personal care arts as fats, oils, fatty alcohols, fatty acids, esters of fatty acids, and combinations thereof, and which aid application and adhesion, yield gloss and/or provide occlusive moistuπzation The emollient compnses from about 1% to about 90%, preferably from about 10% to about 80%, more preferably from about 20% to about 70%, and most preferably from about 40% to about 60%, of the cosmetic composition Suitable emollients for use m the present mvention mclude isosteanc acid denvatives, isopropyl palmitate, lanolin oil, dnsopropyl drmerate, maleated soybean oil, octyl paln-itate, isopropyl isostearate, cetyl lactate, cetyl πcinoleate, tocopheryl acetate, acetylated lanolm alcohol, cetyl acetate, phenyl tnmethicone, glyceryl oleate, tocopheryl hnoleate, wheat germ glycendes, arachidyl propionate, mynstyl lactate, decyl oleate, propylene glycol ncmoleate, isopropyl lanolate, pentaerythntyl tetrastearate, neopentylglycol dicaprylate/dicaprate, hydrogenated coco-glycendes, isononyl isononanoate, lsotndecyl isononanoate, mynstal mynstate, tnisocetyl citrate, cetyl alcohol, octyl dodecanol, oleyl alcohol, panthenol, lanolm alcohol, lmoleic acid, lmolemc acid, sucrose esters of fatty acids, octyl hydroxystearate and mixtures thereof. Examples of other suitable emollients descnbed in the Cosmetic Bench Reference, pp. 1.19-1.22 (1996), which descriptions are incorporated herem by reference. Particularly preferred for use herem are non-polar emollients. By "non-polar emollient," as used herein, means any emollient emulsifier possessmg no permanent electnc moments and wherem the solubility (at 30°C) of the vitamin B 3 compound m the polar emollient is less than about 1.5% preferably less than about 1.0%, more preferably less than about 0 5%. Suitable non-polar emollients mclude, but are not limited to, esters and linear or branched chamed hydrocarbons, examples of which mclude isononyl isononanoate, isopropyl isostearate, octyl hydroxystearate, dusopropyl dimerate, lanolin oil, octyl palmitate, isopropyl palmitate, paπffins, lsoparnfins, acetylated lanolm, sucrose fatty acid esters, isopropyl mynstate, isopropyl stearate, mineral oil, sihcone oils, dimethicone, allantoin, isohexadecane, isododecane, petrolatum, and mixtures thereof. As used herem, the solubility of the vitamm B3 compound in non-polar emollients is determined by the methodology descnbed hereinafter. Suitable oil emollients for use in the compositions of the present invention mclude esters, tnglycendes, hydrocarbons and si cones These can be a smgle mateπal or a mixture of one or more matenals. They will normally comprise from about 1% to about 100%, preferably from about 5% to about 90%, and most preferably from about 70% to about 90% of the emollient component Oils can act as emollients and can also impart viscosity, tackmess, and drag properties to cosmetic compositions such as lipsticks. Examples of suitable oils include capryhc tnglycendes; capnc tnglycende; isosteanc tnglycende; adipic tnglycende, propylene glycol mynstyl acetate; lanolm, lanolm oil; polybutene; isopropyl palmitate, isopropyl mynstate; isopropyl isostearate; diethyl sebacate; dusopropyl adipate; tocopheryl acetate, tocopheryl linoleate; hexadecyl stearate; ethyl lactate; cetyl oleate; cetyl ncmoleate; oleyl alcohol; hexadecyl alcohol; octyl hydroxystearate; octyl dodecanol; wheat germ oil; hydrogenated vegetable oils; castor oil; petrolatum; modified lanolins; branched-cham hydrocarbons; alcohols and esters; com oil; cottonseed oil; olive oil; palm kernel oil; rapeseed oil; safflower oil, jojoba oil; evening primrose oil; avocado oil mineral oil, sheabutter, octylpalmitate, maleated soybean oil, glycerol tπoctanoate, dusopropyl dimerate, and volatile and non-volatile sihcone oils mcludmg phenyl tnmethicone. The preferred oils for use herein are acetylglycendes, octanoates, and decanoates of alcohols and polyalcohols, such as those of glycol and glycerol, the ncinoleates of alcohols and polyalcohols such as cetyl ncmoleate, PG-3 dusostearate, polyglycerol ethers, polyglycerol esters, capryhc tnglycendes, capnc tnglycendes, isosteanc tnglycende, adipic tnglycende, phenyl tnmethicone, lanolm oil, polybutene, isopropyl palmitate, isopropyl isostearate, cetyl ncmoleate, octyl dodecanol, oleyl alcohol, hydrogenated vegetable oils, castor oil, modified lanolins, octyl palmitate, lanolm oil, maleated soybean oil, cetyl ncmoleate, glyceryl tπoctanoate, dusopropyl dimerate, synthetic lanolm denvatives and branched cham alcohols, sucrose esters of fatty acids, octyl hydroxystearate and mixtures thereof. Preferably, the oils used are selected such that the majonty (at least about 75%, preferably at least about 80% and most preferably at least about 99%) of the types of oils used have solubility parameters which do not differ by more than from about 1 to about 0 1, preferably from about 0 8 to about 0 1 Optional Components Solidifying Agent The cosmetic compositions of the present invention may further comprise a solidifying agent to solidify or trap any liquid base matenals m the cosmetic composition As used herem, the term "solidify" refers to the physical and or chemical alteration of the liquid base matenal so as to form a solid or semi- sohd at ambient conditions, l e., to form a final composition which has a stable physical structure and is deposited on the skm dunng normal use conditions. As is appreciated by those skilled m the art, the selection of the particular solidifying agent for use in the cosmetic compositions will depend upon the particular type of composition desired, i.e., gel or wax-based, the desued rheology, the liquid base matenal used and the other materials to be used in the composition. The solidifying agent is preferably present at a concentration of from about 1 to about 90%, more preferably from about 1 to about 50%, even more preferably from about 5% to about 40%, most preferably from about 3% to about 20%. The wax cosmetic stick embodiments of this invention preferably contain from about 5% to about 50% (by weight) of a waxy solidifying agent. The term "waxy solidifying agent," as used herem, refers to a solidifying material having wax-like charactenstics. Such waxy materials may also serve as emollients Among the waxy materials useful herem are the high meltmg point waxes, I e., having a meltmg pomt of from about 65°C to about 125°C, such as beeswax, spermaceti, carnauba, baysberry, candehlla, montan, ozokente, ceresm, paraffin, synthetic waxes such as Fisher-Tropsch waxes, microcrystalline wax, and mixtures thereof Ceresm, ozokerite, white beeswax, synthetic waxes, and mixtures thereof, are among the preferred high-meltmg pomt waxes useful herem. Compositions containing waxes among those useful herem are disclosed m U.S. Patent 4,049,792, Elsnau, issued Sept. 20, 1977, herein incorporated by reference m its entirety). Low meltmg waxes, havmg a melting pomt of from about 37°C to about 75°C, are preferred for use in the wax stick embodiments of this invention Wax stick embodiments of this invention, which contam volatile sihcone oils as a liquid base matenal, preferably contain from about 10% to about 35%o, more preferably from about 10% to about 20% (by weight), of a low-melting wax. Such matenals mclude fatty acids, fatty alcohols, fatty acid esters and fatty acids amides, havmg fatty chains of from about 8 to about 30 carbon atoms, and mixtures thereof Preferred wax-like matenals mclude cetyl alcohol, palmitic acid, stearyl alcohol, behenamide, sucrose esters of tallow fatty acids, mono and di-fatty acid esters of polyethylene glycol, and mixtures thereof. Stearyl alcohol, cetyl alcohol, and mixtures thereof, are particularly preferred Fatty acids, fatty alcohols, and other wax-like matenals useful m this mvention are also disclosed m the following references, all of which are incorporated by reference herem: U.S. Patent 4,151,272, Geary, et al., issued Apr. 24, 1979; U.S. Patent 4,229,432, Gena, issued Oct. 21, 1980; and U.S. Patent 4,280,994, Turney, issued July 28, 1981, "The Chemistry and Technology of Waxes", A. H. Warth, 2nd Edition, reprinted in 1960, Rernhold Publishing Corporation, pp 391-393 and 421, "The Petroleum Chemicals Industry", R. F. Goldstem and A. L Waddeam, 3rd Edition (1967), E & F. N. Span Ltd., pp 33-40; "The Chemistry and Manufacture of Cosmetics", M. G. DeNavarre, 2nd edition ( 1970), Van Nostrand & Company, pp 354-376, and in "Encylopedia of Chemical Technology:, Vol. 24, Kirk- Othmer, 3rd Edition (1979) pp 466-481. Prefened wax-like materials useful as solidifymg agents in the present wax sticks are described m U S. Patent 4,126,679, Davy, et al., issued Nov. 21, 1978, herem incorporated by reference in its entirety. Preferred mixtures of wax-like materials compnse fatty alcohols contammg carbon chains of from about 14 to about 18 carbon atoms, and alcohols having cham lengths of 20 carbons or longer, wherem the final mixture contams from about 1% to about 3% (by weight) of the longer-cham fatty alcohols. Compositions contammg these fatty alcohol mixtures are descnbed in European Patent Specification No 117,070, May, published Aug. 29, 1984 (incorporated by reference herem). Also useful herein are biopolymers such as those described in European Application No. 522624, to Dunphy et al., herem incorporated by reference in its entirety. The gel stick embodiments of this invention preferably contam from about 3% to about 30%, preferably from about 3% to about 10% (by weight), of a solidifymg agent. The particular amount of solidifymg agent to be used will depend upon the particular solidifymg agent and the liquid base matenal used, and the desired physical characteπstics of the gel stick. Solidifymg agents useful m the gel stick embodiments of this invention are, m general, surface-active compounds which form networks immobilizing or solidifying the liquid base materials into a gel. Such solidifying agents include: soaps, such as the sodium and potassium salts of higher fatty acids, I e., acids havmg from 12 to 22 carbon atoms; amides of higher fatty acids; higher fatty acid amides of alkylolammes; dibenzaldehyde-monosorbitol acetals; alkali metal and alkaline earth metal salts of the acetates, propionates and lactates; waxes, such as candehlla and carnauba waxes; and mixtures thereof. Among those solidifymg agents prefened for use m the gel stick embodiments of this mvention are sodium stearate, sodium palmitate, aluminum stearate, alummum magnesium hydroxy stearate, and mixtures thereof. Gel stick compositions contammg solidifymg agents among those useful herem are descnbed in the following patent documents, all incorporated herem by reference m their entirety: U.S. Patent 2,900,306, Slater, issued Aug. 18, 1959; U.S. Patent 3,255,082, Barton, issued June 7, 1966; U.S. Patent 4,137,306, Rubrno, et al., issued Jan. 30, 1979, U.S. Patent 4,154,816, Roehl, et al., issued May 15, 1979; U.S. Patent 4,226,889, Yuhas, issued Oct. 7, 1980; U.S. Patent 4,346,079, Roehl, issued Aug. 24, 1982; U.S. Patent 4,383,988, Teng, et al., issued May 17, 1983; European Patent Specification No. 107,330, Luebbe, et al., published May 2, 1984; and U.S. patent application Ser. No 630,790, DiPietro, filed July 13, 1984. Preferred solidifymg agents useful m the gel stick embodiments of the present mvention are descnbed m European Patent Specification No 24,365 Sampson, et al , published Mar 4, 1981, incorporated herein by reference m its entirety Also useful herein as solidifymg agents are conventional thickening agents Examples of suitable thickeners mclude, but are not limited to, naturally-occurring polymeric matenals such as, locust bean gum, sodium alginate, sodium casemate, egg albumm, gelatm agar, canageenm gum sodium algmate, xanthan gum, quince seed extract, tragacanth gum, starch, chemically modified starches and the like, semi-synthetic polymeric materials such as cellulose ethers (e g hydroxyethyl cellulose, methyl cellulose, carboxymethyl cellulose, hydroxy propylmethyl cellulose), polyvmylpyrro done, polyvinylalcohol, guar gum, hydroxypropyl guar gum, soluble starch, cationic celluloses, catiomc guars and the like and synthetic polymeric materials such as carboxyvmyl polymers, polyvmylpyrrohdone, polyvmyl alcohol polyacryhc acid polymers, polymethacrylic acid polymers, polyvmyl acetate polymers, polyvmyl chlonde polymers, polyvmylidene chloride polymers and the like Inorganic thickeners may also be used such as alumimum silicates, such as, for example, bentomtes, or a mixture of polyethylene glycol and polyethylene glycol stearate or distearate Naturally occurring polymers or biopolymers and their use are further described in European Application No 522624, to Dunphy et al Additional examples of naturally occumng polymers or biopolymers can be found in the Cosmetic Bench Reference, pp 1 40-1 42, herem incorporated by reference Also useful herem are hydrophilic gelling agents such as the acrylic acid/ethyl acrylate copolymers and the carboxyvmyl polymers sold by the B F Goodnch Company under the trademark of Carbopol Registered TM resms These resms consist essentially of a colloidally water-soluble polyalkenyl polyether crosslmked polymer of acrylic acid crosslinked with from 0 75% to 2 00% of a crosslinking agent such as polyallyl sucrose or polyallyl pentaerythπtol Examples include Carbopol 934, Carbopol 940, Carbopol 950, Carbopol 980, Carbopol 951 and Carbopol 981 Carbopol 934 is a water-soluble polymer of acrylic acid crosslinked with about 1% of a polyallyl ether of sucrose havmg an average of about 5 8 allyl groups for each sucrose molecule Also suitable for use herein are carbomers sold under the Trade Name "Carbopol Ultrez 10, Carbopol ETD2020, Carbopol 1382, Carbopol 1342 and Pemulen TR-1 (CTFA Designation Acrylates/10-30 Alkyl Acrylate Crosspolymer) Combmation of the above polymers are also useful herem Other gelling agents suitable for use herem mclude oleogels such as tπhydroxysteann Hydrophobically modified celluloses are also suitable for use herem These celluloses are described in detail in U S Patents 4,228,277 and 5,104,646, both of which are herein incorporated by reference in their entirety Additional examples of suitable gelling agents or gellants can be found m the Cosmetic Bench Reference, p 1 27, herein incorporated by reference Without bemg limited by theory, the solidifymg agent in combination with the emollient is believed to act as an occlusive on the skm by forming continuous or discontinuous bi-layer or multi-layer films on the skm The term "occlusive," as used herein, means a preventing or obstructing something, in this case, preventing the removal of moisture (via evaporation) and the vitamm B 3 compound (via film bmdmg) from the surface of the skm Color Certain embodiments of the present mvention, preferably lipsticks or lip pamts, can contam from 1% to about 90%, preferably from about 1% to about 35%, more preferably from about 1% to about 20% and most preferably from about 5% to about 15%, of color, on an anhydrous pigment weight basis These are usually aluminum, barium or calcium salts or lakes Preferably, dyes are present at from about 0 1% to about 4% and pearls from 0% to about 20% Pigments are typically dispersed in emollients for the good dispersion of the pigments when incorporated into the lip compositions, thus providmg an even distribution of color Colors/pigments suitable for use herem are all inorganic and orgamc colors/pigments suitable for use m lipstick compositions Lakes are either a pigment that is extended or reduced with a solid diluent or an orgamc pigment that is prepared by the precipitation of a water-soluble dye on an adsorptive surface, which usually is aluminum hydrate There is uncertainty in some instances as to whether the soluble dye precipitates on the surface of the aluminum hydrate to yield a dyed inorganic pigment or whether it merely precipitates in the presence of the substrate A lake also forms from precipitation of an insoluble salt from an acid or basic dye. Calcium and barium lakes are also used herem Lakes suitable for use m the present mvention include Red 3 Aluminum Lake, Red 21 Aluminum Lake, Red 27 Alummum Lake, Red 28 Aluminum Lake, Red 33 Aluminum Lake, Yellow 5 Aluminum Lake, Yellow 6 Aluminum Lake, Yellow 10 Aluminum Lake, Orange 5 Alummum Lake and Blue 1 Aluminum Lake, Red 6 Barium Lake, Red 7 Calcium Lake Other colors and pigments can also be mcluded in the lipsticks, such as dyes and pearls, titanium oxides, Red 6, Red 21, Brown, Russet and Sienna dyes, chalk, talc, zmc oxides, iron oxides and titanated micas Dispersants may also be used in conjunction with the colors and pigments of the present mvention Examples of suitable dispersants include, but are not limited to, those described in U S Patent 5,688,493, herein incorporated by reference in its entirety Dermatologicallv Acceptable Anhydrous Carrier The composition of the present invention may further compnse a dermatologically acceptable vehicle or earner, m addition to the emollient component descnbed herem before Such a earner should be compatible with the skm, the nails, the mucous membranes, tissues and the hair and includes any conventionally used cosmetic or dermatological carrier which meets these requirements Such a earner should also be compatible with the crystalline vitamm B 3 compound, in that it should not interact with or substantially dissolve the crystalline vitamm B 3 compound The crystalline vitamm B3 compound is preferably dispersed m the emollient component of the composition The emollient can be part of the earner system. Suitable earners other than the emollients descnbed herem before mclude, but are not limited to, oil-in-water emulsions, water-in-oil emulsions, omtments, lipsticks, foundations, mascaras, powders, suspensions, creams, lotions, gels, foams, mousses and the like. These carriers facilitate topical application and, in some cases, provide additional therapeutic effects, e g., by moisturizing of the affected skm areas Dermatologically acceptable earners can be readily selected by one of ordinary skill m the art Preferably, the earner is substantially anhydrous In this context, "substantially anhydrous" means that the earner provides the composition with less than 20%, preferably less than 5%, more preferably less than 1%, most preferably 0%, by weight of free or unbound water by weight of the composition. Substantially Free of Polar Solvents The present invention is, preferably, substantially free of polar solvents In general, "polar solvents" refers to those solvents that contam hydroxyl and or carbonyl groups and also have high dielectnc constants and strong polanty In general, the phrase "substantially free" means the level of such polar solvents or polar solvent mixtures is preferably less than about 0.5%, more preferably less than 0.1% and is most preferably 0% Without bemg limited by theory, such polar solvents tend to dissolve or otherwise mteract with the crystalline structure of the vitamin B 3 compounds Examples of such polar solvents include, but are not limited to, water, alcohols, such as ethanol, propyl alcohol, isopropyl alcohol, hexanol, and benzyl alcohol; polyols, such as propylene glycol, polypropylene glycol, butylene glycol, hexyleneglycol, maltitol, sorbitol, and glycenne; panthenol dissolved in glycerine; and mixtures thereof. Other Additives Other optional ingredients which can be present in the cosmetic compositions of the present invention include flavor oils, fat soluble vitamins such as vitamin A and E, esters of vitamin A (e.g , acetate, propionate, or palmitate) and of vitamm E (e.g., acetate or sorbate), sunscreens such as octyl methoxycinnamate, butyl methoxydibenzoylmethane, titanium dioxide and zmc oxide, germicides such as tnclosan, anti-inflammatory agents such as hydrocortisone, lipid matenals such as ceramides and hposomes and skm care actives. The cosmetic compositions can comprise ingredients conventionally employed m cosmetic compositions such as mascara, foundation or hpcare products This includes skm care active ingredients such as pharmaceutically active mgredients Skm care actives ingredients in both water soluble and water insoluble forms can be added to the cosmetic compositions of the present mvention These include, but are not limited to vitamm C and its denvatives (e.g., ascorbyl palmitate, ascorbyl phosphate and its salts such as magnesium or sodium), vitamm D, panthenol, chalcones, flavanones, retinoic acid, titanium dioxide, iron oxides, zinc oxide, beta- glycyerhetic acid; chamomile oil, ginko biloba extract, pyroglutamic acid, salts or esters; sodium hyaluronate, 2-hydroxyoctanoιc acid; sulfur; salicylic acid; carboxymethyl cysteme, and mixtures thereof These additives, both fat soluble and water soluble, will normally be present m amounts of less than about 10% by weight, and generally in the range of about 0 01% to about 5%, preferably from about 0.01% to about 3%, most preferably from about 0.1% to about 1%, by weight. Organic binders such as steaπc acid, paraffin, butyl acetate, copolymer of ethylene and vmyl acetate, methacrylic acid butyl ester, dibutyl phthalate, polyester and mixtures thereof can also be used in the present invention. Flavor oils such as peppermint oil, orange oil, citrus oil. wintergreen oil can be used along with an alcohol or glycerme. Flavor oils are usually mixed m a solvent such as ethanol to dilute the flavor. The flavor oils useful herein can be derived from natural sources or be synthetically prepared. Generally flavor oils are mixtures of ketones, alcohols, fatty acids, esters and terpenes. The term "flavor oil" is generally recogmzed m the art to be a liquid which is denved from botamcal sources, i.e. leaves, bark, or skm of fruits or vegetables, and which are usually insoluble m water. The level of flavor oil used can range from 0% to about 5%, preferably from 0% to about 1% Additional moisturizers may also be included mto the present compositions. Prefened moisturizers include pynohdone carboxylic acid, sodium lactate or lactic acid, urea, guanidme, glyceπc acid and its salts (e.g., calcium salt), petrolatum, collagen, -hydroxy propylglyceryl ether, α-hydroxy acids (e.g., ethylglycohc acid, leucic acid, mandelic acid, glyco c acid), glucosammes, and elastin fibers, D- panthenol, allantom and hyaluronic acid and chondroitm sulfate Examples of suitable moisturizers can be found m Cosmetic Bench Reference, p 1.30-1 32 (1996), herein incorporated by reference. Surfactants can also be added to the compositions of the present invention. Suitable surfactants are those capable of forming association structures m contact with a polar solvent. Examples of such surfactants can be found m U S. Patent 5,843,407 to El-Nokaly, herein incorporated by reference. When used, the surfactants are preferably present at concentration of from about 0.1% to about 30%, more preferably 1% to about 15%, most preferably from about 1% to about 5% by weight of the composition. Also useful herein are emulsifiers commonly known as coupling agents. When used, the overall concentration of the emulsifier can be from about 0.1% to about 30%, preferably from 1% to about 15% and most preferably from about 1% to about 15%, most preferably from about 1% to about 5% by weight of the composition. Examples of suitable emulsifiers can be found in U S. Patent 5,085,856 to Dunphy et al.; Japanese Patent Publication Sho 61-83110; European Patent Application EP 522624 to Dunphy et al., U.S. patent 5,688,831 to El-Nokaly et al., and examples of other suitable emulsifiers can be found m Cosmetic Bench Reference, pp. 1.22, 1.24-1.26 (1996), all of which are herein incorporated by reference m their entirety. Mixtures of the above surfactants and emulsifiers can also be used. A prefened optional component is ethyl cellulose (Ethocel). Ethyl cellulose generally is prefened for use at levels of about 5% and more preferably 1%. Another prefened optional component is silica. Silica is generally prefened for use at levels of from about 1% and about 5% Hypoallergenic compositions can be made from the liquid crystal, wax, oil and colors herem. These compositions should not contam fragrances, flavor oils, lanolm, sunscreens, particularly PABA, or other sensitizers or potential sensitizers and untants. The compositions of the present mvention can also be made mto long lasting or non-transferable cosmetic compositions Detailed discussions of such lipsticks are found m Japanese Patent Publication Hei No 6-199630 and European Patent Application 748622, both of which are herem mcorporated by reference in their entirety Additional optional materials that can be incorporated m the compositions of the present invention can be found in PCT application WO 97/39733, to Oblong et al METHODS OF USE The cosmetic compositions of the present mvention are ideally suited for use m treating the skm and lips, especially in the form of a lipstick or lip balm for applying to the lips a permanent or semipermanent color, ideally with a gloss or luster fimsh The cosmetic compositions can also be used in treating the skin and/or lips with a skin care agent for protection agamst exposure to adverse weather, including the wind and the ram, dry and or hot environments, environmental pollutants (e g , ozone, smoke, and the like), or exposure to excessive doses of sunlight The compositions are also useful in providmg sun protection, moisturizing and/or conditioning for the hair and skm, improved skm feel, regulatmg skin texture, reducmg fine lines and wrinkles, reducing oily shine on hair or skm, skm lightening and reducmg The cosmetic compositions can, accordmgly, be applied to the skm and/or lips m the traditional manner using a convement holder or applicator to provide a decorative and/or protective film thereto Methods of Determining Solubility of Vitamin B 3 Compounds in Emollients The solubility of the vitamm B 3 compound in the vanous non-polar emollients of the present mvention can be determined as follows I Preparation of Samples for Analysis 1 ) the emollient is placed m pre-weighted vial and then saturated with a vitamin B 3 compound, 2) the vial is shaken and allowed to sit in a bath at 30°C for 1 hour A small stir bar is used to agitate the contents of the vial If no precipitation occurs in the vial, then more macmamide is added This was repeated until precipitation occuned The sample is left m the bath for an additional 48 hours to insure saturation, 3) the saturated emollient is drawn mto a syringe, 4) A 045 micron filter (Gelman Acrodisc) is fitted on the end the syringe and the emollient is filtered through into separate pre- weighted vial for analysis, 5) The emollient is analyzed usmg HPLC to determine the amount of macmamide therem II Analysis Approximately 0 25g of the sample is weighed (sample weight) into a 15mL plastic screw-cap centnfuge tube The sample is mixed with approximately 3mL of 50/50 v/v methanol/chloroform and homogenized by vortex mixing About 7mL of water is then added to extract the vitamm B 3 compound from the methanol chloroform phase Each sample is mixed by shaking 50 times m a back and forth motion to facilitate transfer of the macmamide from the methanol/chloroform to the water phase This mixmg creates an emulsion at the mterface of the two phases. The emulsion can be dissipated by letting the sample stand for several hours or by bnef centnfugation (15 seconds) at high speed Once the two phases have completely separated, a pipette is used to carefully transfer the aqueous phase mto a separate, pre-weighted vial. The weight of the aqueous phase is noted (aqueous phase weight). An aliquot of the aqueous phase is transfened to an analysis contamer and analyzed for macmamide by HPLC (Waters 2690 Separations Module coupled with a Waters 996 PDA detector, both supplied by Waters Corporations). Ill.Calculations: The percent vitamm B 3 compound is determined by takmg the vitamin B 3 compound concentration measured by HPLC and multiplying by the dilution factor. The dilution factor is the aqueous phase weight divided by the sample weight. EXAMPLES The cosmetic formulations illustrated m Examples I-X illustrate specific embodiments of the cosmetic compositions of the present mvention, but are not intended to be limiting thereof Other modifications can be undertaken by the skilled artisan without departing from the spint and scope of this mvention. These exemplified embodiments of the cosmetic compositions of the present mvention improve the skm penetration of the vitamin B 3 compound while also improving skin feel of the crystallme vitamm B 3 compound. All exemplified compositions can be prepared by conventional formulation and mixing techniques. Such formulation and mixing techniques are descnbed in detail in Harry's Cosmeticologv, pp. 119-141 and 314-354 (J.B. Wilkinson and RJ. Moore 7 th ed 1982). and Cosmetics- Science and Technology, pp. 1-104 and 307-422 (M.S. Balsam and E. Sagarin 2 nd ed 1972), both of which are herem mcorporated by reference m their entirety Component amounts are listed as weight percents and exclude mmor materials such as diluents, filler, and so forth The listed formulations, therefore, comprise the listed components and any minor materials associated with such components Example I - Lipstick Composition Ingredient Amount (weight percent) Ozokente Wax 5.00 Cande lla Wax 3.00 Caranauba Wax 2.00 Cetyl Alcohol 2.00 Cetyl Lactate 2.00 Ascorbyl Palmitate 0.50 Propylparaben 0.10 Vitamm E Acetate 0.05 Isopropyl Isostearate 13.97 Octyl Hydroxystearate 5.20 Paraffin Wax 2.50 Tocopherol nιcotιnate(23%) + castor oιl(77%) 21.74 dispersion (ball milled) Acetylated Lanolm 6.33 Pigment Slurry (30%Pιgment/70%Castor oil) 25.61 'The crystalline tocopherol mcotmate is combmed with castor oil and ball milled to an average crystalline particle size of from about O.Olμm to about 200μm. The milled tocopherol nicotinate/castor oil mixture along with the remaining ingredients of the above formulation are added to a vessel equipped with a heat source and heat the mgredients to a temperature of about 90°C to form a melt. The melt is mixed until homogeneous The mixture is deaerated by vacuum and poured mto the appropriate mold The mixture is cooled to ambient temperature and incorporated mto the appropnate package. The lipstick is applied to the lips to provide color, moistuπzation and improved lip feel Example II-Lipstick Composition Ingredient Amount (weight percent) Ozokente Wax 5.00 Candehlla Wax 3.00 Carnauba Wax 2.00 Cetyl Alcohol 2.00 Cetyl Lactate 2.00 Ascorbyl Palmitate 0.50 Propylparaben 0.10 Vitamm E Acetate 0.05 Isopropyl Isostearate 15.00 Octyl Hydroxystearate 10.00 Paraffin Wax 2.50 macmamide 1 2.50 Castor oil 13.41 Acetylated Lanolm 6.33 Mica SVA 10.00 Pigment Slurry (30%Pιgment/70%Castor oil) 25.61 'The crystallme macmamide is milled with castor oil to an average crystallme particle size of from about O.Olμm to about 200μm The milled macmamide, together with the remaining mgredients of the above formulation, are added to a vessel equipped with a heat source and heat the ingredients to a temperature of about 90°C to form a melt The melt is mixed unttl homogeneous. The mixture is deaerated by vacuum and poured mto the appropnate mold. The mixture is cooled to ambient temperature and mcorporated into the appropnate package. The lipstick is applied to the lips to provide color, moistunzation and improved lip feel. 16 Example Ill-Lipstick Composition Ingredient Amount (weight percent) Glycerme 0.300 Lecithin 2.00 Niacmamide 1 5.00 Octyl Palmitate 11.24 Isopropyl Palmitate 4 80 Bentone 38 1 00 Propylene Carbonate 0.33 Cetyl Recmolate 1 00 Dusopropyl Dimearate 29.88 Lanolin Oil 11.60 Ozokerite 6.75 Candehlla 5.25 Be Square 175 2.00 PG-3 Dnsostearate 2.00 Vitamin "E" Acetate 0 05 Propylparaben 0.15 Methylparaben 0.15 Benzoic Acid 0.10 Mica cf 7.00 Pigments 9.00 Stamers 0.40 'The crystallme macmamide is milled with an emollient (e.g , dusopropyl dimearate) to an average crystalline particle size of from about 0 01 μm to about 200μm In a suitable vessel, the glycerme, lecithin and milled niacmamide are mixed in an appropnate vessel until a liquid crystal phase is formed Separately, the remaining mgredients of the above formulation are added to a vessel equipped with a heat source and heated to a temperature of about 90°C to form a melt The melt is mixed until homogeneous The above liquid crystal phase mixture is added to the melt and mixed until homogeneous. The mixture is deaerated by vacuum and poured mto the appropnate mold The mixture is cooled to ambient temperature and mcorporated mto the appropnate package The lipstick is applied to the lips to provide color, moistunzation and improved lip feel Example IV-Antiperspirant Gel Stick Ingredient Amount (weight percent) Tocopherol nicotinate 1 4 N-Lauroyl-L-glutarmc acid-di-n-butyl amide 2 4 12-hydroxystearιc acid 2 Light mineral oil 3 23 Dusopropyl Sebacate 4 39 Alummum Zirconium 25 Talc 3 'The crystalline tocopherol nicotinate is milled with mineral oil to an average crystallme particle size of from about O.Olμm to about 200μm 2 GP-1 supplied by Ajinomoto, Inc. 3 Benol White Mmeral Oil supplied by Witco Chemical Corp. 4 Schercemol DIS supplied by Scher Cherfficals Inc. The gelling agent, milled tocopherol nicotinate and the liquid base matenal are combined mto a vessel equipped with a heat source. The mixture is heated to a temperature between about 80°C and about 130°C with stirring, until the mixture forms a homogeneous, molten solution. Preferably, the homogeneous, molten solution is allowed to cool to a mixing temperature; typically between about 65°C and 110°C. Next, the antiperspirant active and other mgredients are added to the melt, such as fragrances and colors, into the homogeneous, molten solution m the above vessel with stirring. The mixture is allowed to cool until it begins to thicken and poured mto containers allowing them to cool to ambient temperature. (Although not prefened, the antiperspirant active may alternatively be added along with the gelling agent and the liquid base material in the first step ) An antiperspirant composition, compnsed as above, is applied to the underarm area of a human subject, and has unproved skm feel. Example V-Solid Antiperspirant Stick Ingredient Amount (weight percent) Niacmamide 1 3.0 Stearyl Alcohol 10.0 Hydrogenated Castor Oil-mp 86 degrees C. 9.0 Alummum Chlorohydroxide 40.0 Isopar "V" 2 37.0 Fragrance 1.0 100.0 'The crystallme macmamide is milled to an average crystallme particle size of from about O.Olμm to about 200μm Tsopar "V" Avg. Mol. Wt. 197 B P. Range, 255-301 degrees Celsius. In vessel contammg a heat source, the isoparaffin liquids, the water-insoluble liquid emollients, the surface active agent, and the water-insoluble waxes are heated to a temperature sufficient to form a solution of these materials Next, the aluminum chlorohydroxide is added with gentle agitation, followed by the milled niacmamide and remaining ingredients The solution is mixed until a homogenous suspension is formed The suspension is cooled to a temperature above the solidification pomt and is then poured into suitable contamers An antiperspirant composition, comprised as above, is applied to the underarm area of a human subject, and has improved skm feel Example Vl-Solid Antiperspirant Stick Ingredient Amount (weight percent) Niacmamide 1 1 Steaπc Acid 10 0 Hydrogenated Castor Oil-mp 86 degrees C 5 5 Zirconium Chlorohydroxide 25 0 Talc 10 0 Isopar "M" 2 42 5 Dusopropyl Adipate 5 0 Fragrance 1 0 100 0 'The crystallme macmamide is milled with castor oil to an average crystallme particle size of from about 0 01 μm to about 200μm 2 Isopar "M", Avg Mol Wt 191 B P Range, 207-260 degrees Celsius In vessel contammg a heat source, the isoparaffin liquids, the water-insoluble liquid emollients, the surface active agent, and the water-msoluble waxes are heated to a temperature sufficient to form a solution of these matenals Next, the alummum chlorohydroxide is added with gentle agitation, followed by the milled niacmamide and remaining ingredients The solution is mixed until a homogenous suspension is formed The suspension is cooled to a temperature above the solidification pomt and is then poured mto suitable contamers An antiperspirant composition, comprised as above, is applied to the underarm area of a human subject, and has improved skin feel Example VII-Antiperspirant Cream Ingredient Amount (weight percent) 'Niacmamide 3 0 Mιcrothene FN510 3 6 0 Natrosol 4 2 0 iso-eicosane 5 13 0 Reach AZ 6 26 7 fragrance 0 8 'The crystallme macmamide is milled with dimethicone (350 cs) to a particle size of from about 0 Olμm to about 200μm 2 Colloιdal silica thickening matenal, sold by Cabot Corporation 3 Low density polyethylene powder, sold by U.S.I. Chemicals Hydroxyethylcellulose, sold by Hercules, Inc. 5 2, 2, 4, 4, 6, 6, 8, 8-dimethyl-10-methylundecane, obtamed from Permethyl Corporation, Frazier, PA 6 Zrrcomum-alummum-glycιne hydroxychloπde complex, particulate antiperspirant active matenal, sold by Reheis Chemical Company. The cyclomethicone, iso-eicosane and perfume are added to a stainless steel mixing vessel The Cab-0-Sιl is then added, followed by the Microthene and Natrosol and, finally, the antiperspirant active and milled niacmamide The composition is thoroughly stined after addition of each particulate matenal The composition is then milled, usmg a Black & Decker Die Grinder (Model 4420, type 4) with a 6.35 cm diameter Cowles dispersmg blade at approximately 6,000 rpm, for approximately 5 mmutes until havmg the desired consistency An antiperspirant cream formulation, compnsed as above, is applied to the underarm area of a human subject, and has improved skm feel Example VIII- Waterproof Mascara Ingredient Amount (weight percent) Petroleum Distillate ((IBP 345) 49.570 Glycerol Ester of Tall Oil Rosm 10.000 Bentone 38 CG or Type 5.890 Color(Black 34-3068 or Type) 5.000 Alkylated PVP (220 Type) 5 000 Tnhydroxystearm (R Type) 5.000 Magnesium Carbonate 309 5.000 'Tocopherol mcotinate 5.000 Kaohn 2747 2 000 Carnauba Wax, NF 2.000 Propylene Carbonate 1 940 Polyethylene AC-617A 1.000 Phenoxyethanol 0.800 Color( Yellow 34-3170 or Type) 1.600 Propylparaben, NF 0.100 Tenox BHA 0.100 Total 100.000 'The crystallme tocopherol mcotmate is milled with the petroleum distillate ((IBP 345)to an average crystallme particle size of from about 0 01 μm to about 200μm The milled tocopherol mcotmate and the above mgredients except colorants and gellants/fillers are added mto stainless steel mixing vessel equipped with a heating source. The mgredients are heated to a temperature of about 90°C and mixed using a propeller blade. Once the temperature reaches about 90°C, the mgredients are mixed usmg a dispersator blade at approximately 3500 rpm The pigments are then slowly added dunng the mixing with the dispersator Similarly, the gellants/fillers are added with mixing. The mixing is contmued with the dispersator until the mixture is homogeneous. The mixture is then forced cooled while mixing with the dispersator at 3500 rpm At about 40°C, mixing is discontinued and the mixture is transfened mto an appropnate storage container The mascara composition is applied to the lashes and/or eyebrows to provide softemng, moisturization and unproved feel.. Example IX-Mascara Ingredient Amount (weight percent) Petroleum Distillate (IBP 345) 51.570 Glycerol Ester of Tall Oil Rosin 10.000 Bentone 38 CG or Type 5.890 Magnesium Carbonate 309 5.000 Alkylated PVP (220 Type) 5.000 Tr-hydroxysteann (R Type) 5.000 Talc 2755 4.790 Niacmamide 3.000 Kaolin 2747 2.000 Carnauba Wax, NF 2.000 Propylene Carbonate 1.940 Polyethylene AC-617A 1.000 Phenoxyethanol 0.800 Propylparaben, NF 0.100 Tenox BHA 0.100 Color(Blue 3403516 or Type) 1.810 Total 100.000 The composition is prepared and used as in Example VIII. Example X-Mascara Ingredient Amount (weight percent) Petroleum Distillate (IBP 345) 50.670 Glycerol Ester of Tall Oil Rosm 10.000 Bentone 38 CG or Type 5.890 Magnesium Carbonate 309 5.000 Trihydroxystseaπn (R Type) 5.000 Carnauba Wax, NF 2.000 Niacmamide 10.000 Kaolin 2747 2.000 Propylene Carbonate 1.940 Polyethylene AC-617A 1.000 Phenoxyethanol 0.800 Color 5.500 Tenox BHA 0.100 Propylparaben, NF 0.100 Total 100.000 The composition is prepared and used as Example VIII. Example XI-Lipstick INGREDIENT WT % Polybutene 4.536 Lanolm Oil 18.342 Octoxyglyceryl Behenate 18.342 Stearyl heptanoate 8.856 Jojoba oil 8.856 castor oil 21.78 Butylated hydroxytoluene 0.054 Butylated hydroxyamsole 0.054 Microcrystallme Wax 6 84 Polyethylene 500 6.84 Niacmamide 4.5 (Amphiphlic lipid phase) Lecithm 0475 Cholesterol 0.475 dicetyl phosphate 0.05 In a suitable vessel, neat, chemically synthesized crystalline macmamide is dissolved usmg an appropnate solvent The macmamide is then recrystallized by the s gle solvent method. Next, the recrystallrzed macmamide is combmed with the castor oil and milled to the appropriate particle size Separately, the milled niacinamide/castor oil mixture, polybutene, lanolin oil, octoxyglyceryl behenate, stearyl heptanoate, jojoba oil, butylated hydroxytoluene, butylated hydroxyamsole, microcrystallme wax, polyethylene 500 are added to a vessel equipped with a heat source and heated to a temperature of from about 100-110°C to form a melt The melt is mixed until homogeneous. The lecithm, cholesterol and dicetyl phosphate are mixed separately under nitrogen and at a temperature of about 110°C. The lecithm contammg mixture is then added to the macmamide contammg mixture and mixed until umform. The mixture is deaerated by vacuum and poured mto the appropnate mold. The mixture is cooled to ambient temperature and mcorporated mto the appropnate package. The lipstick is applied to the lips to provide color, moistuπzation and improved lip feel Example XII-Lip Balm INGREDIENT WT % SEFA Cottonate 84.000 Niacmamide 5.000 Candehlla Wax 3.000 Ozokente Wax 1.000 Microcrystallme Wax 1.500 Beeswax 5.300 BHT 0.050 Ethylene Brassylate 0.050 Propylparaben 0.100 100.000 In a suitable vessel, the niacmamide is mixed with SEFA Cottonate and milled to the appropnate particle size. The SEFA Cottonate/niacmamide mixture along with the remaining mgredients are added to a vessel equipped with a heat source and heated to a temperature of from about 80-90°C to form a melt. The melt is mixed until homogeneous. The mixture is deaerated by vacuum and poured into the appropnate mold The mixture is cooled to ambient temperature and mcorporated mto the appropnate package The lipstick is applied to the lips to provide moistuπzation and improved lip feel. Example XIII-Long-LastingCosmetic A An admixture (Part A) is prepared by combining in a suitable vessel the following ingredients: INGREDIENT WT. %. MQ Resin' 43.7 PM99A 2 56.3 1 Tnmethylsiloxysihcate available from GE. 2 Isododecane available from Presperse. The admixture is mixed using conventional mixing techmques until the MQ Resin is dissolved Processing- B. An admixture (Part B) is prepared by combimng in a suitable vessel the following mgredients: INGREDIENT WT. %. SE30 Sihcone Gum' 50.0 PM99A 50.0 1 Available from GE The admixture is mixed using conventional mixing techmques until the SE30 Sihcone Gum is dissolved. C A lipstick contammg Part A and Part B is prepared by combining the following ingredients- INGREDIENTS WT. %. Tocopherol mcotmate 1.00 Part A 47.00 Part B 24.91 Pιgment(s) 10.00 Propylparaben 0.20 PM99A 1.89 Bentone ISD 1 15.00 1 10% bentone, 3% propylene glycol, 87% Isododecane available from Rheox In a suitable vessel, the admixture of Part A along with the pigments, propylparaben, crystallme tocopherol mcotmate and PM99A are combined and mixed usmg a Ross homognizer at about 4,000 rpms for about 10 mmutes or until the mixture is umform (taking care not to ignite the PM99A) The Bentone ISD added to the mixture with mixing at about 4, 000 rpms. until the mixture is umform.. The admixture of Part B is added to the mixture and mixed mitially at high shear, preferably 1600 rpms., to facilitate dispersion usmg a IKA mixer Once sufficient dispersion is achieved, the mixer speed is reduced, preferably to about 1,000 rpms., and the mixture is allowed to mix until uniform. The mixture is then poured into a suitable contamer and tightly capped for storage, preferably at room temperature. The long lastmg cosmetic composition is applied to the skm to provide color, moistuπzation and improved skin feel

Claims: WHAT IS CLAIMED IS: 1. A lipstick composition contammg crystallme vitamin B 3 compoimds, and which provides unproved skm feel, said composition compnsmg: a) from about 0.01% to about 50%, by weight, of a crystallme vitamm B 3 compound having an average particle size of from about O.Olμm to about 200μm; b) from about 1% to about 90%, by weight, of an emollient component; and c) from about 1% to about 90%, by weight, of a solidifymg agent. 2. A lipstick composition according to Claim 1 , wherein the average particle size of the vitamin B 3 compound is from about O.Olμm to about lOOμm. 3. A lipstick composition accordmg to Claim 1, wherem at least 60% of the vitamm B3 compound has a particle size of less than 30μm. 4. A lipstick composition accordmg to Claim 1, wherein said vitamin B3 compound is selected from the group consistmg of macmamide, denvatives of macmamide, non-vasodilatmg esters of nicotinic acid, and combmations thereof. 5. A lipstick composition accordmg to Claim 4, wherein said vitamm B3 compound is selected from the group consisting of niacmamide, tocopherol mcotmate, and combmations thereof 6. A lipstick composition accordmg to Claim 5, wherein said vitamm B3 compound is niacmamide. 7. A lipstick composition accordmg to Claim 1, wherein said vitamm B3 compound is substantially free of salts of the vitamin B3 compound. 8. A lipstick composition accordmg to Claim 1, wherein said vitamm B3 compound is substantially uncomplexed 9. A lipstick composition accordmg to Claim 1, wherein said composition is substantially free of polar solvents. 10. A lipstick composition accordmg to Claun 1, wherem said emollient component comprises from about 10% to about 80% of the cosmetic composition. A lipstick composition accordmg to Claim 10, wherem said oil comprises from about 5% to about 90% of the emollient component A lipstick composition accordmg to Claun 10, wherem said emollient is a non-polar emollient A lipstick composition accordmg to Claim 10, wherem said oil is selected such that at least about 75% of the types of oils used have solubility parameters which do not differ by more than from about 0 1 to about 1 A lipstick composition accordmg to Claim 13, wherem said oil is selected such that at least about 99% of the types of oils used have solubility parameters which do not differ by more than from about 0 1 to about 1 5 A lipstick composition according to Claim 1, further compnsrng from about 0 1% to about 35% of a color A lipstick composition accordmg to Claim 1 wherem the vitamm B 3 compound is dispersed in the emollient A method of improvmg the perceived skm feel of crystallme vitamm B 3 compounds by applymg to the skm a safe and effective amount of the lipstick composition m Claim 1 A lipstick composition according to Claun 1 wherem the composition compnses less than about 10%, by weight of the composition formed, of water A topical cosmetic composition providmg improved skm feel of crystallme vitamm B 3 compounds, said composition compnsrng a) from about 0 01% to about 50%, by weight, of a crystallme vitamm B 3 compound havmg an average particle size of from about 0 01 μm to about 200 μm, and b) from about 1%> to about 90%, by weight, of an emollient component The composition accordmg to Claim 19 wherem the vitamm B 3 compound is macmamide The composition according to Claim 19 wherem the vitamm B 3 compound is dispersed m the emollient 22. The composition according to Claim 19 wherein the average particle size of the vitamin B 3 compound is from about O.Olμm to about lOOμm. 23. The composition according to Claim 19 wherein the composition is substantially free of polar solvents. 24. The composition according to Claim 19 wherein the vitamin B 3 compound is dispersed in the emollient.

Inventors: VATTER MICHAEL LEE, WALLING DAVIS WILLIAM, VATTER, MICHAEL, LEE, WALLING, DAVIS, WILLIAM
Applicants: PROCTER & GAMBLE, THE PROCTER & GAMBLE COMPANY
Application year: 2000
Main classification: A61K7
IPC codes: A61K8, A61Q1, A61Q15