PREPARATION OF ALKYLTHIO- AND/OR ARYLTHIO-SUBSTITUTED DIKETO-DIARYL-PYRROLOPYRROLES

Abstract: Preparation of alkylthio and/or arylthio-substituted diketo-diaryl-pyrrolopyrroles (DPPs) of formula (Ia) and dithio-bridged bis-diketo-diaryl-pyrrolopyrroles (bis-DPPs) of formula (Ib), in which in formula (Ia) G is phenyl substituted by at least one arylthio or alkylthio group, and G1 is G or a carbocyclic or heterocyclic radical, by reacting a haloaryl with a thiol or thiolate, and in formula (Ib) G5 is a phenylene, G6 is G1 but not G, and G7 is alkylene, cycloalkylene or phenylene, by reacting two haloaryls with a dithiol or dithiolate, which comprises reacting a thiol or thiolate with a halo-diketo-diaryl-pyrrolopyrrole ("halo-DPP") of formula (IIa) in which G2 is a halogenated phenyl group and G3 is G2 or G1, or reacting a dithiol or dithiolate with two halo-diketo-diaryl-pyrrolopyrroles ("halo-DPPs") of formula (IIb) in which Hal is halogen such as fluorine, chlorine, bromine or iodine, and G6 is G1, and also novel DPPs and also bis-DPPs, compositions comprising DPPs of formula (Ia) prepared in accordance with the invention, and their uses.

Description: - 1 - Preparation of alk y lthio- and/or arylthio-substituted diketo-diaryl-pyrrolopyrroles The present invention relates to an improved process for preparing alkylthio- and/or arylthio- substituted diketo-diaryl-pyrrolopyrroles (DPPs) of the formula la and dithio-bridged bis- diketo-diaryl-pyrrolopyrroles (bis-DPPs) of the formula lb lb, in which in formula la G is phenyl substituted by at least one arylthio or alkylthio group, and G, is G or a carbocyclic or heterocyclic radical, by reacting a haloaryl with a thiol or thiolate, and in formula lb G 5 is a phenylene, G 6 is G but not G, and G7 is alkylene or phenylene, by reacting two haloaryls with a dithiol or dithiolate. The invention additionally relates to novel, arylthio- or alkylthio-substituted DPPs, their use, and compositions comprising the DPPs of the invention. US 4,579,949 and US 4,490,542 describe the preparation of DPPs substituted by at least one thioether group by reacting arylthio- or alkylthio-substituted benzonitriles with succinic esters. Disadvantages are the low yields in the case of long-chain alkylthio-DPPs and the impossibility of obtaining water-soluble compounds. The reaction of DPP pigments with thiols to give alkylthio- or arylthio-substituted DPPs gives incomplete conversions owing to the poor solubility of these pigments. Chemistry Letters 1978, 13-14 discloses that unactivated haloaryls can be substituted only in the presence of catalysts. - 2 - It was therefore an object of the invention to provide an improved process for preparing alkylthio- and/or arylthio-substituted DPPs which permits in particular the preparation of water-soluble compounds and long-chain alkylthio-DPPs. In particular, the process should be operable without high pressures and the use of catalysts. In addition, the economics of the process should be guaranteed by high yields. Furthermore, the invention was to provide novel, thioether-substituted diketo-diaryl-pyrrolopyrroles and also dithioether-bridged bis- DPPs which can be used in compositions with high molecular mass organic material, in particular as colorants. In addition, the thioether-substituted DPPs should be able to be used, in particular, as crystal growth inhibitors or rheology enhancers. Accordingly, we have found the process defined at the outset, which involves reacting a thiol or thiolate with a halo-diketo-diaryl-pyrrolopyrrole ("halo-DPP") of the formula I la in which G 2 is an unsubstituted or substituted, halogenated phenyl group and G 3 is G 2 or Gi, or reacting a dithiol or dithiolate with two halo-diketo-diaryl-pyrrolopyrroles ("halo- DPPs") of the formula lib Hal lib, in which Hal is halogen such as fluorine, chlorine, bromine or iodine, preferably chlorine or bromine and, with particular preference, chlorine, Hal being, in particular, in the para position of the phenylene. Customarily, the reaction is started by bringing the thiol and/or thiolate or the dithiol and/or the dithiolate into contact with the halo-DPP Ha or Mb by conventional methods, for example by mixing the starting materials or by dropwise addition of one starting material to the other. To prepare the compounds of the formula la the molar ratio of thiol to halo-DPP of the formula lla is generally chosen to be within the range from 0.1 :1 to 20:1 , preferably in the range from 2:1 to 5:1 and, with particular preference, in the range from 2.1 :1 to 2.7:1 , and, to prepare the compounds of the formula lb, the molar ratio of dithiol to halo-DPP of the formula Mb is generally chosen to be in the range from 0.5:1 to 20:1 , preferably in the range from 0.5:1 to 5:1 and, with particular preference, in the range from 1 :1 to 2.7:1. Preferably, the reaction temperature is chosen to be within the range from 323 to 453 K, preferably in the range from 333 to 433 K, with particular preference in the range from 343 to 423 K and, with very particular preference, in the range from 343 to 413 K. The reaction pressure is chosen to be generally within the range from 70 kPa to 10 MPa, preferably from 90 kPa to 5 MPa; atmospheric pressure is particularly preferred. The reaction time depends generally on the reactivity of the starting materials, the chosen reaction temperature and the desired conversion. The reaction time is customarily chosen to be within the range from 15 minutes to 2 days. In one preferred embodiment the reaction is conducted under an inert gas atmosphere using for this purpose preferably nitrogen or noble gases such as helium or argon. Particular preference is given to reaction in a nitrogen atmosphere. In addition, the reaction can be carried out with or without solvent, with preference being given to reaction in a solvent. Preferred solvents are organic solvents or solvent mixtures such as aprotic, especially non-aqueous aprotic, solvents. Aprotic solvents may be apolar, such as benzene, chlorobenzene and chlorinated hydrocarbons, or polar. The latter are particularly preferred. Examples of polar aprotic solvents which can be used are amides such as hexamethyl- phosphoramide, carboxamides such as N,N'-dimethylformamide and N,N'- dimethylacetamide, or lactams such as N-methylpyrrolidone, N-methyl- 2-piperidone, 1 ,3-dimethyl-3,4,5,6-tetrahydro-3(1 H)pyrimidinone or N-methyl- 4-piperidone, or urea bases such as N.N'-dimethylethyleneurea, N,N'-dimethyl- propyleneurea, and also acetonitrile, sulfolane, dimethyl sulfoxide, or aromatic solvents such as nitrobenzene. - 4 - Preference is given to N,N'-dimethylformamide, N,N'-dimethylacetamide, dimethyl sulfoxide, 1 ,3-dimethyl-3,4,5,6-tetrahydro-3(1 H)pyrimidinone or N-methyl- pyrrolidone. The weight ratio of halo-DPP lla or halo-DPP lib to the solvent lies in general within the range from 0.5 to 10% by weight, with particular preference in the range from 1 to 5% by weight and, with very particular preference, in the range from 2 to 3% by weight. In another preferred embodiment the reaction is conducted in the presence of a base. Examples of suitable bases are alkali metal carbonates, for example Na 2 CO 3 or K 2 CO 3 , alkali metal hydrogencarbonates, for example NaHCO 3 or KHCO 3) alkali metal hydroxides, for example NaOH or KOH, alkali metals, such as sodium or potassium, and also aromatic bases, such as pyridine, N,N'- dimethylaminopyridine or quinoline. Preference is given to non-aqueous alkali metal bases and to aromatic bases, particular preference to non-aqueous alkali metal carbonates or alkali metal hydrogencarbonates, and very particular preference to anhydrous K 2 CO 3 . The molar ratio of base to thiol or thiolate lies customarily within the range from 0.5:1 to 5:1 , preferably in the range from 1 :1 to 4:1 and, with particular preference, in the range from 1 :1 to 3: 1 , and the molar ratio of base to dithiol or dithiolate lies customarily within the range from 1 :1 to 10:1 , preferably within the range from 1 :1 to 5:1 and, with particular preference, in the range from 1 :1 to 4:1. In a preferred embodiment of the process of the invention the reaction is conducted in the presence of a solvent or solvent mixture and a base. If desired, the reaction can also be conducted in the presence of catalysts, especially transition metal catalysts, examples being tetrakis(triphenyl- phosphine)palladium(O), -nickel(O), and -platinum(O), and -ruthenium(ll) chloride. Preferably, the reaction is conducted without a catalyst. - 5 - If a catalyst is used, it is generally employed in a proportion within the range from 0.001 to 10% by weight, based on halo-DPP of the formula lla or lib, and preferably from 0.5 to 7% by weight and, with particular preference, from 2 to 5% by weight based on the total amount of reactants. The reaction mixture can be worked up by conventional methods, for example by filtration and subsequent washing of the filter residue and subsequent optional drying. The product may be an individual compound or a mixture of differently substituted compounds of the formula la, or a mixture consisting of halo-DPP lla and a compound of the formula la, or else a mixture consisting of halo-DPP lib and a compound of the formula lb and/or la. In accordance with observations made to date the thiol or thiolate employed can comprise any known thiols or thiolates, examples being substituted or unsubstituted aryl or alkyl thiolates, it being possible for the latter to be branched or straight-chain, uninterrupted, or interrupted one or more times by heteroatoms. In a preferred embodiment a thiol or thiolate of the formula Ilia or a dithiol or dithiolate of the formula 1Mb is used. R SR 2 Ilia, R 2 S-G 7 -SR 2 lllb in which R can be CrC 30 alkyl which can be uninterrupted or interrupted one or more times by heteroatoms, such as -O- or -S-, or by -NH-, -C(O)O-, -O-C(O)- or -C(O)-NH-, and can be substituted or unsubstituted, or can be C 5 -Cι 2 cycloalkyl or phenyl, each of which can be substituted or unsubstituted, and R 2 is hydrogen, a cation ("M") of an alkali metal, or an organic nitrogen base, and G can be CrC 30 alkylene which can be uninterrupted or interrupted one or more times by heteroatoms, such as -O- or -S-, or by -NH-, -C(O)O-, -O-C(O)- or -C(O)- NH-, and can be substituted or unsubstituted, or - 6 - can be C 5 -Cι 2 cycloalkylene or phenylene, each of which can be substituted or unsubstituted. Ci-C∞alkyl is methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, sec-amyl, tert-amyl, hexyl, 2,2-dimethylbutyl, heptyl, octyl, 2-ethylhexyl, 1 ,1 ',3,3'- tetramethylbutyl, nonyl, decyl, dodecyl, tetradecyl, hexadecyl, octadecyl, eicosyl, heneicosyl, docosyl, tetracosyl, pentacosyl, hexacosyl, heptacosyl, octacosyl or nonacosyl, preference being given to CrC 18 alkyl such as methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, sec-amyl, tert-amyl, hexyl, 2,2-dimethylbutyl, heptyl, octyl, 2-ethylhexyl,1 ,1 ',3,3'-tetramethylbutyl, nonyl, decyl, dodecyl, tetradecyl, hexadecyl and octadecyl and particular preference to C 8 -Cι 8 alkyl such as octyl, 2-ethylhexyl, 1 ,1 ',3,3'-tetramethylbutyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl or octadecyl and very particular preference to Cι 2 -C 18 alkyl such as dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl or octadecyl; particular preference is also given to d-C 8 alkyl such as methyl, ethyl, propyl, isopropyl, n-butyl, iso-butyi, sec-butyl, tert-butyl, n-pentyl, sec-amyl, tert-amyl, hexyl, 2,2'-dimethylbutyl, heptyl, octyl, 2-ethylhexyl and 1 ,1 ',3,3'-tetramethylbutyl. CrC 30 alkylene is methylene, ethylene, propylene, isopropylene, n-butylene, isobutylene, sec- butylene, tert-butylene, n-pentylene, sec-amylene, tert-amylene, hexylene, 2,2'- dimethylbutylene, heptylene, octylene, 2-ethylhexylene, 1 ,1 ',3,3'-tetramethylbutylene, nonylene, decylene, dodecylene, tetradecylene, hexadecylene, octadecylene, eicosylene, heneicosylene, docosylene, tetracosylene, pentacosylene, hexacosylene, heptacosylene, octacosylene or nonacosylene, preference being given to CrCι 8 alkylene such as methylene, ethylene, propylene, isopropylene, n-butylene, isobutylene, sec-butylene, tert-butylene, n-pentylene, sec-amylene, tert-amylene, hexylene, 2,2'-dimethylbutylene, heptylene, octylene, 2-ethylhexylene, 1 ,1 ',3,3'- tetramethylbutylene, nonylene, decylene, dodecylene, tetradecylene, hexadecylene or octadecylene, and particular preference to C 8 -C 18 alkylene such as octylene, 2-ethylhexylene, 1 ,1 ',3,3'- tetramethylbutylene, nonylene, decylene, dodecylene, tetradecylene, hexadecylene or octadecylene; in addition, particular preference is given to C C 8 alkylene such as methylene, ethylene, propylene, isopropylene, n-butylene, isobutylene, sec-butylene, tert-butylene, n-pentylene, sec-amylene, tert-amylene, hexylene, 2,2'-dimethylbutylene, heptylene, octylene, 2-ethyl- hexylene or 1 ,1 ',3,3'-tetramethylbutylene. C 5 -C 12 cycloalkyl is for example cyclopentyl, cyclohexyl, cycloheptyl or cyclooctyl, preferably C 5 -C 6 cycloalkyl such as cyclopentyl or cyclohexyl. C 5 -C 1 cycloalkylene is for example cyclopentylene, cyclohexylene, cycloheptylene or cyclooctylene, preferably C 5 -C 6 cycloalkylene such as cyclopentylene or cyclohexylene. Alkyl radicals or alkylene radicals of at least two carbon atoms, represented by Ri or G 7 , can be interrupted one or more times by for example -O-, -NH-, -C(O)O-, -O-C(O)-, -C(O)-NH-; preference is given to -C(O)O- or -O- and very particular preference to the -C(O)O- interrupted alkyl radical -CH 2 -C(O)O-CH 2 CH 3 , or the singly -O-interrupted alkyl radical such as -CH 2 -CH 2 -O-CH 2 -CH 3 , or the doubly -O-interrupted alkyl radical such as -CH 2 -CH 2 -O- CH 2 — CH 2 —O— CH 2 — CH 3 . In addition, the alkyl or cycloalkyl radicals or the phenyl radical of R 1 can be substituted by, for example, the following radicals: C C 18 alkyl, OR 3 , S-R 3 , C(O)R 3 , COOR 3 , -OCOR 3 , SO 3 R 3 , SO 2 R 3 , PO 3 R 3 , Si(OR) 3 , a salt radical such as S-M, O-M, COOM, SO 3 M, PO 3 M, P(R 3 ) 3 + X " , P((R 3 ) 2 R 4 ) 3 + X " , NO 2 , N(R 3 ) 3 + X " , N((R 3 ) 2 R 4 ) 3 + X " or a nitrogen-containing radical, in which R 3 and R 4 independently of one another are hydrogen, CrC 18 alkyl, especially methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, sec-amyl, tert-amyl, hexyl or 2,2-dimethylbutyl, or are C 5 -C 6 cycloalkyl or unsubstituted or R 7 -substituted phenyl, M is a cation of an alkali metal, preferably sodium or potassium, X " is a halide, such as fluoride, chloride, bromide or iodide, and R 7 is hydrogen, halogen such as F, Cl, Br, I or is CrC 8 alkyl or unsubstituted or NR 3 R 4 - substituted C 5 -C 6 cycloalkyl. Preferred OR 3 is OH, and preferred S-R 3 is SH. - 8 - Preferred radicals COOR 3 are COOH, COOCH 3 , COOC 2 H 5 , COOC 4 H 9) COOC 5 Hn, and preferred -OCOR 3 is -O-CO-C(CH 2 )-CH 3 . Preferred radicals SO 3 R 3 are SO 3 H, SO 3 (C 5 H 4 )R 7 , SO 3 (C 5 H 5 ), SO 3 CH 3 , SO 3 C 2 H 5 , and preferred radicals SO 2 R 3 are SO 2 (C 5 H 4 )R 7 , SO 2 (C 5 H 4 ) or SO 2 CH 3 . Preferred radicals PO 3 R 3 are PO 3 H, PO 3 (C 5 H 4 )R 7 or PO 3 CH 3 . Preferred nitrogen-containing radicals are selected from the group consisting of NR 3 R 4 , especially NH 2 , NHR 3 or N(R 3 R 4 ), with particular preference being given to substituted alkyl radicals, such as (R 3 R 4 )N-(C C 30 alkyl)-, especially (CH 3 ) 2 N-C 2 H 5 -, further preferred nitrogen-containing radicals are selected from the group consisting of CONHNH 2 , CONHR 3 , NHCOR 3 , NCO and a heterocyclic radical and a compound selected from the group of the formulae IV to IX NR 3 R 4 / N=C π -Mrvru R c -N[(CH 2 Λ) r .-MNΠR. 3 DR 4 .1] 2 . IV V VI VII I and ^^ .N, NR 3 R 4 XDO VIII IX selected in particular from the group of the compounds of the formulae IV and V, in which R 5 independently of R 7 has the same definition as R 7 , and R 6 is a direct bond, -CH 2 -, -CH(CH 3 )-, -C(CH 3 ) 2 -, -CH=N-, -N=N-, -O-, -S-, -SO-, -SO 2 - or -NR 3 -, and r is zero or an integer from 1 to 17. Furthermore, the alkylene, cycloalkylene or phenylene radical of G can be substituted by, for example, the following radicals: halogens such as fluorine, chlorine, bromine or iodine, preferably chlorine or bromine and, with particular preference, chlorine; -E-Cι-C 1β al yl, in which E is -O-, -S-, -NH-, -C(O)O-, -OC(O)-, -NHC(O)-, -C(O)NH-; CN, NO 2 , CF 3 or d-dβalkyl, which can be uninterrupted or interrupted one or more times by heteroatoms, such as -O- or -S-, or by -NH-, -C(O)O-, -O-C(O)- or -C(O)-NH-. If E is -O-, then -O-Cι-Cι 8 alkyl can be methoxy, ethoxy, n-propoxy, isopropoxy, hexadecyloxy or octadecyloxy, preferably methoxy or ethoxy and, with very particular preference, methoxy. If E is -S-, then -S-CrCι 8 alkyl can be methylmercapto, ethylmercapto, n-propylmercapto, isopropylmercapto, hexadecylmercapto or ocatdecylmercapto, preferably methylmercapto or ethylmercapto and, with very particular preference, methylmercapto. If E is -NH-, then -NH-C Ci 8 alkyl can be methylamine, ethylamine, n-propylamine, isopropylamine, hexadecylamine or octadecylamine, preferably methylamine or ethylamine and, with very particular preference, methylamine. If E is -C(O)O- then -C(O)O-Cι-Cι 8 alkyl can be methoxycarbonyl, ethoxycarbonyl, n-propoxycarbonyl, isopropoxycarbonyl, hexadecoxycarbonyl or octadecoxycarbonyl, preferably methoxycarbonyl or ethoxycarbonyl and, with very particular preference, methoxycarbonyl. If E is -OC(O)- then -OC(O)-C Cι 8 alkyl can be a methyl, ethyl, n-propyl, isopropyl, hexadecyl or octadecyl ester radical, preferably a methyl or ethyl ester radical and, with very particular preference, a methyl ester radical. If E is -C(O)NH- then -C(O)NH-C Cι 8 alkyl can be a methyl-, ethyl-, n-propyl-, isopropyl-, hexadecyl- or octadecylaminocarbonyl radical, preferably a methyl- or ethylaminocarbonyl radical and, with very particular preference, methyl- aminocarbonyl radical. If E is -NHC(O)- then -NHC(O)-CrCι 8 alkyl can be a methyl-, ethyl-, n-propyl-, isopropyl-, hexadecyl- or octadecylcarbonylamino radical, preferably a methyl- or - 10 - ethylcarbonylamino radical and, with very particular preference, methylcarbonylamino radical. Preferred substituted alkylene radicals for G 7 are symmetrically substituted radicals such as -(CH 2 ) m -CH(C 1 -C 3 oalkyl)-(CH 2 )m or -(CH 2 ) m -C(C 1 -C 3 oalkyl) 2 -(CH 2 ) m , in which m is an integer in the range from 1 to 14, with particular preference an integer in the range from 3 to 8. Preferred substituted phenylene radical G 7 possesses one or two substituents such as halogen, Cι-C 18 alkyl, -O-d-Cι 8 alkyl, -S-C Cι 8 alkyl, -NH-C C 18 alkyl, CN, NO 2 or CF 3 , where the substituents can be identical or different. Heterocyclic radical is, for example, a five-membered nitrogen-containing heterocyclic radical such as imidazolyl, pyrazolyl, triazolyl, pyrrolyl, pyrrolidinyl, oxazolyl or thiazolyl, a six- membered nitrogen-containing heterocyclic radical such as piperazinyl, piperidinyl, pyridinyl or morpholinyl, or a bicyclic radical which possesses a fused-on five-membered nitrogen- containing heterocycle and a six-membered aromatic ring, such as benzoxazolyl, indolyl, benzothiazolyl, benzimidazolyl or benzotriazolyl. Examples of suitable organic nitrogen bases for R 2 are pyridine, morpholine, N,N'- dimethylaminopyridine and quinoline. Particular preference is given to thiols such as d-C 18 alkyl-SH, especially H-S-(CH 2 ) n -CH 3 , in which n is an integer from 8 to 17, H-S-CH 2 COOC 2 H 5 , H-S-CH 2 CH 2 COOC 2 H 5 , H-S-(para- methylphenyl), H-S-(para-hydroxyphenyl), and also H-S-(CH 2 ) n ι-NR 3 R 4 in which n1 is an integer from 8 to 18, H-S-(CH 2 ) 2 N(CH 3 )2, and also thiolates such as sodium salts or potassium salts of ' S-(d-Cι 8 alkyl), " S-(CH 2 ) 2 -OH, ' S-CH 2 COOC 2 H 5 , ' S-(para-methylphenyl), ' S-(para-hydroxyphenyl) or ' S-(CH 2 ) 2 N(CH 3 ) 2 . Particularly preferred dithiols are -S-(Cι-C 18 alkylene)-S-, especially -S-(C 3 -C 8 alkylene)-S-, such as -S-(CH 2 ) 3 -S-, -S-(CH 2 ) -S-, -S-(CH 2 ) 5 -S-, -S-(CH 2 ) 6 -S-, -S-(CH 2 ) 7 -S- or -S-(CH 2 ) 8 -S-, and very particularly preferred dithiols are -S-(CH 2 ) 3 -S-, -S-(CH 2 ) 5 -S- or -S-(CH 2 ) 6 -S-. The thiols, dithiols or thiolates, dithiolates of the formula Ilia or lllb are obtainable commercially or by known methods for preparing thiols, dithiols or thiolates, dithiolates - 1 1 - (Houben-Weyl, Methoden der organischen Chemie, Volume E 11 , pp. 32-63, Georg Thieme Verlag, Stuttgart, New York, 1985; and J.L. Wardell, "Preparation of Thiols", in S. PATAI (ed.), The chemistry of the thiol group, pp. 163-269, John Wiley & Sons, London, New York, 1974). In the process of the invention a halo-DPP of the formula lla is used in which G 2 is a halogenated phenyl group and G 3 is G 2 or G 1 t and G 3 is preferably G 2 or a carbocyclic or heterocyclic radical and with particular preference is G 2 ; in other words, the halo-DPP of the formula lla in that case is a symmetrically substituted halo-DPP. If G 3 or G 6 is d, then the radical involved can also be a heterocyclic radical which corresponds to the above definition of heterocyclic radicals and is additionally pyrimidine, thiophene or furan, or else the radical involved can be a carbocyclic group of the formula XI, XII or XIII _Slo R - R 8 R 9 ^A ^R 9 XI XII x „i in which Re, Fig, Rio and Rn independently of one another are hydrogen, halogen such as fluorine, chlorine, bromine or iodine or Cι-Cι 8 alkyl, R 10 -E-d-C 18 alkyl, -CN, -NO 2 , trifluoromethyl, C 5 -C 6 cycloalkyl or -C=N— R and in particular hydrogen, d-C 5 alkyl such as methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, sec-amyl or tert-amyl, or halogen such as Cl or Br, and R1 2 is a single bond, -CH 2 -, -CH(CH 3 )-, -C(CH 3 ) 2 -, -CH=N-, -N=N-, -O-, -S-, -SO-, -SO 2 - or -NR 3 -. 12 With particular preference, halo-DPP of the formula lib together with G 6 is an organic radical such as R 40 40 R -SJ 2, 40 N- i or R 41 R 41 in which R 40 and R 41 independently of one another are hydrogen, halogen such as fluorine, chlorine, bromine or iodine, or d-Cι 8 alkyl, -E-d-d 8 alkyl, -CN, -NO 2 or trifluoromethyl. With very particular preference G 6 is an organic radical such as in which R 42 and R 3 independently of one another are hydrogen, chlorine, methyl, tert-butyl or -CN. In one preferred embodiment the halogenated phenyl group G employed is a compound of the formula XIV -ζy x,v in which Hal is halogen such as fluorine, chlorine, bromine or iodine, preferably chlorine or bromine. With particular preference, halogen is in the para position. If desired, the halogenated phenyl group G 2 can be a compound of the formula XV _ ^ Hal XV \^ R 1,3 13 and can carry further substituents, R 13 or R 14 , where Rι 3 and R i independently of one another are, for example, hydrogen, CN, CF 3 , Cι-C 5 alkyl, C 5 -C 6 cycloalkyl, -E-d-C 18 alkyl, phenyl, S-Ri, amides such as -CONR 3 R 4 or amides of the formulae XVI to XIX -CONR, XStr * -CONR XVI N NR 3 R 4 -CONR XVIII XIX or amides of nitrogen-containing heterocycles such as 1 -carbonyi-imidazoie, -pyrazole, -triazole, -pyrrole, -pyrrolidine, -benzimidazole or -benzotriazole, or halogen such as fluorine, chlorine, bromine or iodine, preferably chlorine or bromine. Preferably, Rι 3 and R 14 are in the meta positions. In a further preference, R 14 is hydrogen and R 13 is one of the above substituents other than hydrogen, preferably in the meta position. In another preferred embodiment the halogenated phenyl group G 2 is of the formula XX XX in which Hal is preferably fluorine, chlorine, bromine or iodine and, with particular preference, chlorine or bromine. - 14 Halo-DPPs II with correspondingly substituted groups are known, for example, from patents US 5,484,943, US 5,616,725 or US 5,200,528 or are obtainable in accordance with US 4,579,949. A further embodiment of the present invention relates to new DPPs of the formulae XXI and XXX R , 115 R 16 R 15 R 16 XXI XXX and to novel bis-DPPs of the formula lb lb, in which R 15 , R 16 , R 20 and R 2 ι independently of one another are hydrogen or R 13 or R 1 , and G 4 is a carbocyclic or heterocyclic radical, with the proviso that (a) Ri in formula XXI is not phenyl if Rι 5 and R 16 are hydrogen and G 4 is phenyl, and (b) Ri in formula XXX is not phenylene(d-C 4 alkyl) or d-C 12 alkyl if R 15 , R 16 , R 2 o and R 21 are hydrogen, and G 5 is a phenylene, G 6 is a carbocyclic or heterocyclic radical, and G 7 is alkylene, cycloalkylene or phenylene. Preferred DPPs of the formula XXI or XXX are those in which Ri is mono- or polysubstituted or unsubstituted d-doalkyl or a phenyl radical. With particular preference, Rι 5 , Riβ, R20 and R 2 ι are hydrogen and Ri is -d-Cι 8 alkyl, such as C alkyl, C 6 alkyl, C 9 alkyl, C 12 alkyl or Cι 8 alkyl, and also -(para- 15 phenylene)-OH, -CH 2 CH 2 OH, -CH 2 C(O)O-CH 2 CH 3 , -(CH 2 ) 2 C(O)O-CH 2 CH 3 - (d-C 30 alkylene)-N(R 3 ,R 4 ) such as -(C 2 H 5 )-N(CH 3 ) 2 . Particular preference is given to compounds of the formula lb in which G 5 is 1 ,4- phenylene and G 7 is n-propylene, n-butylene, n-pentylene, n-hexylene, n-heptylene or n-octylene, or substituted or unsubstituted phenylene and G 6 is unsubstituted or substituted phenyl. Very particular preference is given to compounds of the formula lb in which G 5 is 1 ,4-phenylene and G 7 is n-propylene, n-butylene, n-pentylene, n-hexylene, n-heptylene or n-octylene and G 6 is unsubstituted phenyl. Very particular preference is given to compounds of the formula XXXI or XXXII (C 1 -C 30 alkylene)-N(C 1 -C 8 alkyl) 2 30 XXXI or XXXII, in which R 3 o is -C3oalkyl, with particular preference Cι-Cι 8 alkyl and, with very particular preference, C 5 -d 8 alkyl. A further embodiment of the present invention relates to compositions comprising a DPP of the formula la and a halo-DPP of the formula lla, obtainable by the process of the invention using a substoichiometric amount of thiol or thiolate of the formula Ilia. Preferably, the thiol or thiolate of the formula Ilia is employed in a molar ratio that is within the range from 0.1 to 49%, based on the total amount of thiol or thiolate of the formula Ilia and halo-DPP of the formula lla. - 16 - A further embodiment of the process of the invention relates to compositions comprising at least two differently substituted DPPs of the formula la. These compositions are obtainable either by reacting at least two differently substituted halo-DPPs of the formula lla with a thiol or thiolate of the formula Ilia or, conversely, by reacting at least two differently substituted thiols or thiolates of the formula Ilia with a halo-DPP of the formula lla. The molar ratio of thiol or thiolate of the formula Ilia to differently substituted halo-DPPs of the formula lla, or of differently substituted thiols or thiolates of the formula Ilia to halo-DPP of the formula lla, is generally chosen to be within the range from 20:0.1 to 1 :1 , preferably in the range from 10:1 to 5:1 and, with very particular preference, within the range from 5:1 to 5:2. The molar ratio of the differently substituted halo-DPPs of the formula lla to one another is generally chosen to be within the range from 0.1 to 99.9 mol-%, based on the total amount of differently substituted halo-DPPs of the formula lla, and is preferably in the range from 20 to 80 mol-% and, with particular preference, in the range from 40 to 60 mol-%. The molar ratio of differently substituted thiols or thiolates of the formula Ilia to one another is generally chosen to be within the range from 0.1 to 99.9 mol-%, based on the total amount of differently substituted thiols or thiolates of the formula Ilia, is preferably within the range from 20 to 80 mol-% and, with particular preference, in the range from 40 to 60 mol-%. The invention relates, furthermore, to compositions comprising a DPP of the formula XXI and/or XXX and/or DPP la and/or lb and diketo-diaryl-pyrrolopyrrole (DPP) or a DPP latent pigment, wherein DPPs of formula XXI and la, or XXX and lb are different. DPP latent pigments are described, for example, in US 5,616,725. In a preferred embodiment, the molar ratio of DPP of the formula XXI and/or XXX to DPP, DPP of the formula la or lb, or DPP latent pigment is chosen to be within the range from 0.1 to 99.9 mol-%, based on the total amount of DPP of the formula XXI or XXX, DPP or DPP latent pigment, more preferably from 20 to 80 mol-% and, with particular preference, from 40 to 60 mol-%. - 17 - These compositions of the invention can be prepared by customary methods, for example, by mixing the individual components with one another in accordance with the customary methods, in analogy, for example, to the method described in US 5,200,528. The DPPs can be prepared by customary methods as described in US 5,200,528. Similarly, the DPP latent pigments can be prepared in analogy to the method described in US 5,561 ,232. Furthermore, the invention relates to the use of DPP of the formula la and/or lb as rheology enhancers or as crystal growth inhibitors. A further embodiment of the present invention relates to the use of DPPs of the formula XXI or XXX as rheology enhancers or as crystal growth inhibitors. In addition, the invention relates to a rheology enhancer or crystal growth inhibitor comprising DPP of the formula la and/or lb. In common practice the rheology enhancers or crystal growth inhibitors are used in compositions comprising DPP of the formula la and/or lb and DPP or DPP latent pigment. A further embodiment of the present invention relates to compositions comprising DPP of the formula la and/or lb and DPP or DPP latent pigment. The present invention relates further to a method of enhancing rheology or of inhibiting crystal growth which comprises incorporating an effective amount of DPP of the formula la and/or lb in DPP or a DPP latent pigment. The molar ratio of DPP of the formula la and or lb is usally in the range from 0.1 to 20 mol-% based on of DPP of the formula la and/or lb and DPP or DPP latent pigment. Furthermore, the present invention relates to the use of DPP of the formula XXI or XXX or bis-DPP lb, or of a composition comprising a DPP of the formula XXI and/or XXX and/or DPP la and/or lb and diketo-diaryl-pyrrolopyrrole (DPP) or a DPP latent pigment, wherein DPPs of - 18 - formula XXI and la, or XXX and lb are different, for colouring/pigmenting high molecular mass organic material. The invention additionally relates to a method of colouring/pigmenting high molecular mass organic material which comprises incorporating a colouristically effective amount of DPP of the formula XXI or XXX or of bis-DPP lb, or of a composition comprising a DPP of the formula XXI and/or XXX and/or DPP la and/or lb and diketo-diaryl-pyrrolopyrrole (DPP) or a DPP latent pigment, wherein DPPs of formula XXI and la, or XXX and lb are different, therein, by conventional methods, as described, for example, in US 5,200,528. In addition, the invention relates to compositions comprising high molecular mass organic material and DPP of the formula XXI or XXX or bis-DPP of the formula lb. In general the weight ratio of DPP of the formula XXI or XXX or bis-DPP of the formula lb or the compositions of the invention is from 0.01 to 30% by weight, preferably from 0.1 to 10% by weight, based on the high molecular mass organic material. Another preferred embodiment of the present invention relates to compositions consisting of high molecular mass organic material and DPP of the formula XXI or XXX or bis-DPP of the formula lb and also compositions consisting of DPP of the formula XXI or XXX or bis-DPP of the formula lb and/or high molecular mass organic material and/or DPP of the formula la and also compositions consisting of DPP of the formula XXI or XXX and/or high molecular mass organic material and/or DPPs and also compositions consisting of DPP of the formula XXI or XXX and/or high molecular mass organic material and/or DPP latent pigments and also compositions consisting of DPP of the formula XXI or XXX and/or high molecular mass organic material and/or halo-DPP of the formula lla and also compositions consisting of DPP of the formula lb and/or high molecular mass organic material and/or halo-DPP of the formula lib. High molecular mass organic materials can be of natural or synthetic origin. They may, for example, comprise natural resins or drying oils, rubber or casein, or modified natural substances, such as cellulose ethers or esters, cellulose acetate, cellulose propionate, cellulose acetobutyrate or nitrocellulose, and especially entirely synthetic organic polymers (thermosets and thermoplastics) as obtained by addition polymerization, polycondensation, - 19 - or polyaddition. From the class of the addition-polymerization resins mention may be made primarily of polyolefins, such as polyethylene, polypropylene or polyisobutylene, and also substituted polyolefins, such as addition polymers of vinyl chloride, vinyl acetate, styrene, acrylonitrile, acrylates and/or methacrylates or butadiene, and also addition copolymers of the abovementioned monomers, especially acrylonitrile-butadiene-styrene (ABS) or ethylene- vinyl acetate (EVA). From the series of the polyaddition resins and polycondensation resins mention may be made of the condensation products of formaldehyde with phenols, known as phenolic resins, and of the condensation products of formaldehyde with urea, thiourea and melamine, known as amino resins, the polyesters used as film-forming resins, both saturated, such as alkyd resins, and unsaturated, such as maleate resins, and also the linear polyesters and polyamides, and silicones. The abovementioned high molecular mass organic materials can be present individually or in mixtures, as plastic masses or melts which can if desired be spun to fibre. They can also be present in the form of their monomers or in the polymerized state in dissolved form as film formers or binders for coating materials or printing inks, such as linseed oil varnish, nitrocellulose, alkyd resins, melamine resins and urea-formaldehyde resins, or acrylic resins. The colouring/pigmentation of the high molecular mass organic substances with the DPPs of the formula XXI or XXX or bis-DPP of the formula lb or compositions of the invention comprising them takes place in general with the resultant crude product of the process of the invention, or following appropriate conditioning and aftertreatment, for example, in such a way that DPP of the formula XXI or XXX or bis-DPP of the formula lb or compositions of the invention comprising them, as they are or in the form of master batches, are admixed to these substrates using roll mills or mixing or milling apparatus. The coloured/pigmented material is generally brought into the desired final form by techniques known per se, such as calendering, compression moulding, extrusion, spreading, pouring or injection moulding. It is often desirable, in order to produce nonrigid mouldings or to reduce their brittleness, to add plasticizers to the high molecular mass compounds prior to their forming. Examples of such plasticizers are esters of phosphoric, phthalic or sebacic acid. The plasticizers can be incorporated into the polymers before or after the incorporation of the colorant. It is also - 20 - possible, in order to obtain different shades, to add fillers and/or other colouring constituents, such as white, coloured or black pigments in the desired amount to the high molecular mass organic substances in addition to DPPs of the formula XXI or XXX or bis-DPPs of the formula lb. For pigmenting coating materials and printing inks, the high molecular mass organic materials and DPPs of the formula XXI or XXX or bis-DPP of the formula lb or compositions of the invention comprising them alone or together with additives such as fillers, other pigments, siccatives or plasticizers are customarily dissolved or finely dispersed in a common organic solvent or solvent mixture. In this context it is possible to follow a procedure whereby the individual components are dispersed or dissolved individually or else two or more are dissolved or dispersed together and only then are all the components combined. The resultant brightly coloured/pigmented high molecular mass materials, examples being plastics, fibres, coatings and prints, are notable for very high colour strength, high saturation, good dispersibility, high fastness to overcoating, heat, light and weather, and high lustre. The process of the invention allows the preparation of a broad range of thio-substituted DPPs of the formula la, and even of long-chain alkylthio-DPPs and water-soluble DPPs, and also of dithio-bridged bis-DPPs of the formula lb. The DPPs of the formula la, the bis-DPPs of the formula lb and the compositions of the invention comprising a DPP of formula XXI or XXX are colorants of high lustre and transparency. The DPPs of the formula la and also the compositions of the invention comprising a DPP of formula XXI or XXX are particularly suitable for inhibiting crystal growth and enhancing rheology. The novel compounds or compositions and the compounds prepared by the process of this invention have good warp fastness properties in high molecular weight material, in particular in material that is processed by the injection moulding process using the novel compounds or compositions. Preferred high molecular weight materials are, for example, polyolefins. The high yields obtained with the process of the invention, and its simplicity, which permits operation without elevated pressure and without catalysts, moreover, are a guarantee of good economics. - 21 - Examples: Example 1 : Reaction of 1 -octadecanethiol with diketobis(4-chiorophenyl)pyrrolopyrrole (DPP of the formula XXII, = halo-DPP of the formula lla with G 2 = G 3 = para-CI-phenyl) 17.19 g (60 mmol) of 1 -octadecanethiol dissolved in 60 ml of dimethylacetamide, DMA, are added dropwise under nitrogen to a red suspension of 10.72 g (30 mmol) of DPP XXII and 9.95 g (72 mmol) of potassium carbonate in 260 ml of DMA. The resultant mixture is then heated at 393 K for 24 hours, during which it turns violet. Workup and isolation: The reaction mixture is cooled to room temperature and then poured into 60 ml of ice water. The aqueous reaction mixture is filtered. The filter residue is washed with methanol and then with water and subsequently dried in vacuo at 353 K. This gives 24.37 g (94.7% of theory by weight) of a red pigment. Examples 2-10: see Tables 1 , 2, 3 and 4 below Examples 11-21 : The reactions take place in analogy to that of Example 1 but, in contradistinction to Example 1 , using instead of the DPP of the formula XXII in Example 11 diketo-4,4'-dibromo(diphenyl)pyrrolopyrrole (DPP of the formula lla with G 2 = G 3 = para-Br-phenyl); in Examples 12 and 13 diketo-4,4',3,3'-tetrachloro(diphenyl)pyrrolopyrroie (DPP of the formula lla with G 2 = G 3 = para.meta-dichlorophenyl); in Example 14 diketo-4-chloro(diphenyl)pyrrolopyrrole, (DPP of the formula lla with G 2 ≠ Gi; G 2 = para-chlorophenyl and = phenyl); in Example 15 diketo-4-chloro-4-methyl(diphenyl)pyrrolopyrrole (DPP of the formula lla with G 2 ≠ Gi; G 2 = para-chlorophenyl and Gi = para-methylphenyl); in Example 16 diketo-4-chloro-4-tert-butyl(diphenyl)pyrrolopyrrole (DPP of the formula lla with G 2 ≠ Gi; G 2 = para-chlorophenyl and = para-tert-butylphenyl); in Example 17 diketo-4-chloro-4-phenyl(diphenyl)pyrrolopyrrole (DPP of the formula lla with G 2 ≠ Gύ G 2 = para-chlorophenyl and ^ = para-phenylphenyl); in Example 18 diketo-3-bromo(diphenyl)pyrrolopyrrole (DPP of the formula lla with G 2 ≠ Gι;G 2 = meta-bromophenyl and Gi = phenyl); - 22 - in Examples 19-21 (preparation of bis-DPP) diketo-4-chloro-4-phenyl(diphenyl)pyrrolopyrrole (DPP of the formula lib with G 2 = para-chlorophenyl and G 6 = phenyl) is employed and in Examples 22-28 the reaction takes place in analogy to that of Example 1 but, in contradistinction to Example 1 , using instead of the DPP of the formula XXII in Example 22 (composition comprising a halo-DPP XXII and a DPP lla with Gg = G 3 = para- Cl-phenyl) thiol in a substoichiometric amount with respect to halo-DPP XXII, and in Example 23 using in this case 1 ,3-dimethyl-3,4,5,6-tetrahydro-3(1 H)pyrimidinone instead of the solvent DMA, and in Examples 24-28 varying the bases. - 23 Table 1 : Examples 1-28, whose reaction takes place in analogy to that of Example 1 , the altered starting materials, experimental parameters and yields being indicated in the table. Example Amount Thiol Amount of Amount Base Amount Reaction of DPP thiol of of base time (g) dissolved in solvent (g) /temp. solvent (ml) (h)/(K) (ml) 1 10.72 1 -octa17.19 g in 260 ml K 2 CO 3 9.95 24/393 decanethiol 60 ml DMA DMA 2 10.72 2-mercapto- 4.21 ml in 260 ml K 2 CO 3 9.95 2/393 ethanol 40 ml DMA DMA 3 10.72 1 -nonane- 9.62 ml in 260 ml K 2 CO 3 9.95 4.5/403 thiol 40 ml DMA DMA 4 10.72 ethyl thio- 7.24 g in 260 ml K 2 CO 3 9.95 19/371 glycolate 40 ml **DMSO "DMSO 5 10.72 p-methyl- 7.45 g in 260 mi K 2 CO 3 9.95 18.5/383 thiophenol 40 ml DMA DMA 6 10.72 4-mercapto- 9.25 g in 260 ml K 2 CO 3 9.95 17/393- phenol 40 ml DMA DMA 403 7 10.02 1 -propane- 6.39 g in 230 ml K 2 CO 3 9.28 19.5/403 thiol 30 ml DMA DMA 8 10.72 1 -dodecane- 15.18 g in 350 ml K 2 CO 3 10.36 16/393 thiol 50 ml DMA DMA 9 5.36 2-dimethyl- 6.37 g in 130 ml K 2 CO 3 4.98 22.5/383 amino- 40 ml ** DMSO ethanethiol * * DMSO 10 5.36 1 -hexane- 3.55 g in 170 ml K 2 CO 3 4.98 18.3/393 thiol 40 ml DMA DMA 1 1 5.35 1 -octa10.32 g in 130 ml K 2 CO 3 4.98 6.25/413 decanethiol 20 ml DMA DMA 12 2.34 1 -nonane- 5.29 in 70 ml K 2 CO 3 1 .82 18.5/393 thiol 10 ml DMA DMA 24 Example Amount Thiol Amount of Amount Base Amount Reaction of DPP thiol of of base time (g) dissolved in solvent (g) /temp. solvent (ml) (h)/(K) (ml) 13 2.34 1-nonane- 5.29 in 80 ml K 2 CO 3 1.82 18.5/393 thiol 10 ml DMSO" DMSO" 14 9.04 2-dimethyl- 8.35 g in 250 ml K 2 CO 3 1.82 20/373 amino- 30 ml DMSO" ethanethiol DMSO" 15 10.1 2-dimethyl- 8.35 g in 250 ml K 2 CO 3 1.82 20/373 amino- 30 ml DMSO" ethanethiol DMSO" 16 5.68 2-dimethyl- 8.35 g in 250 ml K 2 CO 3 1.82 20/373 amino- 30 ml DMSO" ethanethiol DMSO" 17 9.97 2-dimethyl- 8.35 g in 250 ml K 2 CO 3 1.82 20/373 amino- 30 ml DMSO" ethanethiol DMSO" 18 4.04 1 -octa6.3 g in 130 ml K 2 CO 3 3.65 6/403 decanethiol 10 ml DMA DMA 19 4.84 1,3- 1.62 g 100 ml K 2 CO 3 2.9 6/380 propane- DMA dithiol 20 4.84 1,5- 2.04 g 100 ml K 2 CO 3 2.9 6/380 pentane- DMA dithiol 21 4.84 1 ,5-hexane- 1.41 g 100 ml K 2 CO 3 2.9 6/380 dithiol DMA 22 5.36 2-dimethyl- 1.06 g in 130 ml K 2 CO 3 2.07 0.5/353 amino- 20 ml DMSO ethanethiol DMSO 23 10.72 1 -octa17.19 g in 260 ml Λ K 2 CO 3 9.95 24/393 decanethiol 60 m| Λ - 25 - Example Amount Thiol Amount of Amount Base Amount Reaction of DPP thiol of of base time (g) dissolved in solvent (g) /temp. solvent (ml) (h)/(K) (ml) 24 10.72 1 -octa17.19 g in 260 ml Na 2 C0 3 9.95 24/393 decanethiol 60 ml 25 10.72 1 -octa17.19 g in 260 ml KHC0 3 9.95 24/393 decanethiol 60 ml 26 10.72 1 -octa17.19 g in 260 ml Na 9.95 24/393 decanethiol 60 ml 27 10.72 1 -octa17.19 g in 260 ml KOH 9.95 24/393 decanethiol 60 ml 28 10.72 1 -octa17.19 g in 260 ml NaOH 9.95 24/393 decanethiol 60 ml ** DMSO is dimethyl sulfoxide Λ 1 ,3-Dimethyl-3,4,5,6-tetrahydro-3(1 H)pyrimidinone Table 2: Examples 1 -28, whose workup and isolation takes place in analogy to that of Example 1 Example Amount of Methanol Water Drying Yield ice water temperature (g/% of theory (ml) (ml) by weight) (K) 1 600 + + 353 24.37g/ 94.7% 2 600 300 * + 353 12.21 g/ 92.4% 3 600 (1.5 1) 353 16.83 g 92.7% 4 600 *** + + 343 12.65 g/ 80.4% 26 Example Amount of Methanol Water Drying Yield ice water temperature (g/% of theory (ml) (ml) by weight) ( ) 5 600 + O 343 14.96 g/ 93.4% 6 600 (150 ml) 343 15.17g/ 94.2% 7 500 (1.51) (1.51) 343 9.98 g/ 81.4% 8 700 (11) (0.81) 353 19 g/ 92.1% 9 300 (11) (0.51) 343 7.12 g/ 96.0% 10 300 (11) (0.51) 343 7.11 g/ 91.0% 11 300 (1.51)"" (1 I)"" 343 8.5 g/ 82.6% 12 200 (0.5I) 343 1.82 g/ ***** 49.1% 13 200 (0.5I) 343 2.41 g/ ***** 65.0% 14 500 + (1.51) + (11) 343 10.6 g/ 96.7% 15 500 + (1.51) + (11) 343 11.88 g/ 97.65% 16 500 (1.51) (11) 343 6.6 g/ 98% 17 500 (1.51) (11) 343 10.76 g/ 92% 18 300 (1-51) (0.751) 343 5.74 g 91.1% 19 200 ( 0.51) (0.21) 343 4.53 g/ 88.7% - 27 Example Amount of Methanol Water Drying Yield ice water temperature (g/% of theory (ml) (ml) (K) by weight) 20 200 ( 0.5 I) ( 0.2 I) 343 5.22 g/ 98.2% 21 200 ( 0.5 I) ( 0.2 I) 343 5.27 g/ ****** 97.2% 22 300 ( 0.5 I) ******* 343 4.97 g 23 600 + + 353 94% 24 600 + + 353 99% 25 600 + + 353 95% 26 600 + + 353 96% 27 600 + + 353 98% 28 600 + + 353 99% "+" means: component is used in the reaction "-" means: component is not used in the reaction *Example 2: The filter residue is taken up in 300 ml of methanol and stirred at room temperature, T 295 K, for 12 h. The methanolic reaction mixture is filtered. The filter residue is washed with water. ***Example 4: The reaction mixture is poured into 600 ml of ice water and neutralized with concentrated hydrochloric acid until the pH reaches 7. The aqueous reaction mixture is filtered. The filter residue is washed with methanol and water. ****Example 11 : After the filter residue has been washed with methanol and then with water, it is admixed with ethyl acetate, heated to boiling temperature and stirred at this temperature for 2 hours. The reaction mixture is subsequently filtered and the filter residue is dried in vacuo at 343 K. ***** Examples 12 and 13: After the filter residue has been washed with water, it is admixed with ethyl acetate, heated to boiling temperature and stirred at this temperature for 6 hours. The reaction mixture is subsequently filtered and the filter residue is dried in vacuo at 343 K. ****** Examples 19-21 : As under ***** but using DMA in this case instead of ethyl acetate. * * ****** Example 22: After the filter residue has been washed with water, it is admixed with 300 ml of methanol/water (1 :1) and stirred at room temperature. The reaction mixture is 28 subsequently filtered and the filter residue is washed with 300 ml of methanol and then with 300 ml of water and subsequently dried in vacuo at 343 K. Table 3: Elemental analyses of Examples 1 -21 Analysis: C H N Cl S Example 1 : calculated: 75.65% 9.87% 3.27% - 7.48% found: 75.61% 9.67% 3.38% - 7.46% Example 2: calculated: 59.98% 4.58% 6.36% - 14.56% found: 59.67% 4.66% 6.25% - 14.66% Example 3: calculated: 71.48% 8.00% 4.63% - 10.60% found: 71.40% 8.10% 4.38% - 10.46% Example 4: calculated: 59.53% 4.61% 5.34% - 12.22% found: 59.74% 4.16% 6.05% - 12.22% Example 5: calculated: 72.16% 4.54% 5.26% - 12.04% found: 72.25% 4.54% 5.25% - 11.96% Example 6: calculated: 67.15% 3.76% 5.22% - 1 1.95% found: 65.73% 4.19% 5.52% - 11.24% Example 7: calculated: 66.03% 5.54% 6.42% - 14.69% found: 66.17% 5.43% 6.66% - 14.75% Example 8: calculated: 73.21% 8.87% 4.07% - 9.31 % found: 73.08% 8.49% 4.11% - 9.28% Example 9: calculated: 63.13% 6.11% 11.33% - 12.96% found: 63.17% 6.13% 10.73% - 13.03% Example 10: calculated: 69.19% 6.97% 5.38% - 12.31% found: 69.96% 6.88% 5.64% - 11.49% Example 11 : calculated: 75.65% 9.87% 3.27% - 7.48% found: 75.63% 9.84% 3.36% - 7.30% Example 12: calculated: 64.17% 6.88% 4.16% 10.52% 9.52% found: 63.66% 6.83% 4.35% 10.68% 9.07% Example 13: calculated: 69.19% 6.97% 5.38% 12.31 % found: 69.96% 6.88% 5.64% 11.49% Example 14: calculated: 69.19% 6.97% 5.38% 12.31% found: 69.96% 6.88% 5.64% 11.49% 29 Analysis: C H N Cl S Example 15: calculated: 69.19% 6.97% 5.38% 12.31% found: 69.96% 6.88% 5.64% 11.49% Example 16: calculated: 69.19% 6.97% 5.38% 12.31 % found: 69.96% 6.88% 5.64% 1 1.49% Example 17: calculated: 69.19% 6.97% 5.38% 12.31% found: 69.96% 6.88% 5.64% 11.49% Example 18: calculated: 69.19% 6.97% 5.38% 12.31% found: 69.96% 6.88% 5.64% 11.49% Example 19: calculated: 68.81% 4.15% 8.23% 9.42% found: 68.82% 3.99% 8.37% 9.56% Example 20: calculated: 69.47% 4.55% 7.9% 9.05% found: 69.32% 4.71 % 7.86% 9.52% Example 21 : calculated: 69.79% 4.74% 7.75% 8.87% found: 69.32% 4.63% 7.67% 9.43% 30 Table 4: List of compounds of Examples 1 to 28 R 17 R /~"^ \ " ^ Λ ° V o HN jT NH H . j NH Examples Examples R 25 R π 18 2 Rl7ι Rl8 = "S-(CH2)l7CH3 1 , G 7 = propylene 19 Rl9ι R25 = H 23-28 and 22 (Example 22 composition with halo-DPP) Ri7t 18 = -S-(CH2)2"OH G 7 = pentylene 20 Rl9ι R2S = H 2 Ri7ι R18 = -S-(CH 2 )βCH 3 G7 = hexylene 21 R191 R25 = H 3 Rl7, Rl8 = -S-CH2-COO- CH 2 CH3 4 R19. R25 = H R17. 18 = -S-phenyl-(para- methyl) 5 Ri9ι 25 — H R17, Rιβ = -S-phenyl-(para- hydroxy) 6 R19. R25 = H Rl7. Rl8 = -S-(CH2)2CH3 Ri9ι R25 = H 7 R17. 8 = -S-(CH2)nCH3 SUBSΏTUTE SHEET (RULE 26) 31 - R 17 R —v HN \ C NH Examples R \ 25 R n 18 R 17 , R 1β = -S-(CH 2 ) 2 N(CH 3 )2 i9. 25 = H 9 R17, l8 = -S-(CH2)δCH3 R19. R25 = H 10 Rl7ι Rl8 = "S-(CH2)l 7 CH3 Ri9> R25 = H 11 Rl7ι Rl8 = -S-(CH2)βCH3 Ri9> R25 = Cl 12,13 R 17 = -S-(CH 2 ) 2 N(CH 3 )2 Ri9> R25. Rl8 = H 14 R17 = -S-(CH 2 )2N(CH 3 ) 2 R19. R25 = H 15 R l 8= -CH3 R 17 = -S-(CH 2 )2N(CH 3 ) 2 R19. R25 = H 16 Rl8= "O(CH3)3 R 17 = -S-(CH 2 )2N(CH 3 )2 R19. 25 = H 17 Ri8= -phenyl R19 = -S-(CH2) l7 CH3 Rl7> 251 R18 = H 18

Claims: - 32 - WHAT IS CLAIMED IS: 1. A process for preparing an alkylthio- and/or arylthio-substituted diketo-diaryl- pyrrolopyrrole (DPP) of the formula la or a dithio-bridged bis-diketo-diaryl-pyrrolopyrrole (bis-DPP) of the formula lb lb, in which in formula la G is phenyl substituted by at least one arylthio or alkylthio group, and Gi is G or a carbocyclic or heterocyclic radical, by reacting a haloaryl with a thiol or thiolate, and in formula lb G 5 is a phenylene, G 6 is Gi but not G, and G 7 is alkylene, cycloalkylene or phenylene, by reacting two haloaryls with a dithiol or dithiolate, which comprises reacting a thiol or thiolate with a halo-diketo-diaryl-pyrrolopyrrole ("halo- DPP") of the formula lla in which G 2 is a halogenated phenyl group and G 3 is G 2 or Gi, or reacting a dithiol or dithiolate with two halo-diketo-diaryl-pyrrolopyrroles ("halo-DPPs") of the formula Mb - 33 - in which Hal is halogen such as fluorine, chlorine, bromine or iodine. 2. A process according to claim 1 , wherein the thiol or thiolate employed is a compound of the formula Ilia or a dithiol or dithiolate of the formula lllb Rι-SR 2 Ilia, R 2 S-G 7 -SR 2 lllb in which R T can be Cι-C 30 alkyl which can be uninterrupted or interrupted one or more times by heteroatoms, such as -O- or -S-, or by -NH-, -C(O)O-, -O-C(O)- or -C(O)-NH-, and can be substituted or unsubstituted, or can be C 5 -C 12 cycloalkyl or phenyl, each of which can be substituted or unsubstituted, and R 2 is hydrogen, a cation ("M") of an alkali metal, or an organic nitrogen base, and G 7 can be Cι-C 30 alkylene which can be uninterrupted or interrupted one or more times by heteroatoms, such as -O- or -S-, or by -NH-, -C(O)O-, -O-C(O)- or -C(O)-NH-, and can be substituted or unsubstituted, or can be C 5 -Cι 2 cycloalkylene or phenylene, each of which can be substituted or unsubstituted. 3. A process according to claim 2, wherein the substituents of the alkyl radical, of the cycloalkyl radical or of the phenyl radical are C C 18 alkyl, OR 3 , S-R 3 , C(O)R 3 , COOR 3 , -OCOR 3 , SO3R3, SO 2 R 3 , PO3R3, Si(OR) 3 , a salt radical such as S-M, O-M, COOM, SO 3 M, PO 3 M, P(R 3 ) 3 + X ' , P((R 3 ) 2 4 )a + X ' , NO 2 , N(R 3 ) 3 + X ' , N((R 3 ) 2 R 4 ) 3 + X ' or a nitrogen-containing radical, in which - 34 - R 3 and R 4 independently of one another are hydrogen, d-C 18 alkyl, C 5 -C 6 cycloalkyl or unsubstituted or R 7 -substituted phenyl, M is a cation of an alkali metal, preferably sodium or potassium, X ' is a halide, such as fluoride, chloride, bromide or iodide, and R 7 is hydrogen, halogen such as F, Cl, Br, I or is d-C θ alkyl or unsubstituted or NR 3 R 4 - substituted C 5 -C 6 cycloalkyl. 4. A process according to claim 1 , wherein G 2 in halo-DPP of the formula lla is an unsubstituted or substituted, halogenated phenyl group and G 3 is G 2 or d, or G 6 in halo- DPP of the formula lib is Gi, in which Gi is a heterocyclic radical or a carbocyclic group of the formulae XI, XII, XIII fc 0 -^ R« t R Q ~ \^^- Λ „9 R "i11 XI XII x ,„ in which Re, R9, R10 and Rn independently of one another are hydrogen, halogen such as F, Cl, Br or I or CrCι 8 alkyl, , R 10 -E-d-Ciβalkyl, -CN, -NO 2 , trifluoromethyl, C 5 -C 6 -cycloalkyl, or -C=N— ? -R^ in which E is -O-, -S-, -NH-, -C(O)O-, -OC(O)-, -(CO)NH-, -NHC(O)-, and R12 is a single-bond, -CH 2 -, -CH(CH 3 )-, -C(CH 3 ) 2 -, -CH=N-, -N=N-, -O-, -S-, -SO-, -SO 2 - or -NR 3 -. 5. A process according to claim 1 or 4, wherein G 2 is a compound of the formula XV -Q XV «1C4 ; in which Hal is fluorine, chlorine, bromine or iodine and 35 Rι 3 and R 14 independently of one another are, for example, hydrogen, CN, CF 3 , d-C 5 alkyl, C 5 -C 6 cycloalkyl, -E-d-Cι 8 alkyl, phenyl, S-RL amides, such as -CONR 3 R 4 or amides of the formulae XVI to XIX -CONR, NR 3 R 4 -CONR 3 — <\ /)— R, NR 3 R 4 c 3 XVI XVII R~ 1 3 N NR 3 R 4 -CONR XVIII XIX or amides of nitrogen-containing heterocycles such as 1 -carbonyl-imidazole, -pyrazole, -triazole, -pyrrole, -pyrrolidine, -benzimidazole or -benzoatriazole, or halogen such as fluorine, chlorine, bromine or iodine. 6. A process according to one of claims 1 to 5, wherein the reaction is conducted in the presence of a base. 7. A process according to one of claims 1 to 6, wherein the reaction is conducted in the presence of a solvent. 8. An alkylthio- and/or arylthio-substituted diketo-diaryl-pyrrolopyrrole (DPP) of the formula XXI or XXX R 15 XXI XXX - 36 - or a bis-DPP of the formula lb lb, in which R 15 , R 16 . R20 and R 2 ι independently of one another are hydrogen or R 13 or Rι 4 , and G 4 is a carbocyclic or heterocyclic radical, with the proviso that (a) R 1 in formula XXI is not phenyl if R 15 and Rι 6 are hydrogen and G 4 is phenyl, and (b) R 1 in formula XXX is not phenylene(Cι-C 4 alkyl) or Cι-d 2 alkyl if R 15 , R 16ι R 20 and R 21 are hydrogen, and G 5 is a phenylene, G 6 is a carbocyclic or heterocyclic radical, and G 7 is alkylene, cycloalkylene or phenylene. 9. A composition comprising a DPP of the formula XXI and/or XXX according to claim 8 and DPP la and/or lb and diketo-diaryl-pyrrolopyrrole (DPP) or a DPP latent pigment, wherein DPPs of formula XXI and la, or XXX and lb are different. 10. A composition comprising a DPP of the formula XXI or XXX or bis-DPP of the formula lb according to claim 8 and a high molecular mass organic material. 11. The use of a DPP of the formula la or bis-DPP of the formula lb prepared according to claim 1 as a rheology enhancer. 12. The use of a DPP of the formula la or bis-DPP of the formula lb prepared according to claim 1 as a crystal growth inhibitor. 13. The use of a DPP of the formula XXI or XXX or bis-DPP of the formula lb according to claim 8, or of a composition according to claim 9 for colouring/pigmenting high molecular mass organic material.

Inventors: HAO ZHIMIN, ROCHAT ALAIN CLAUDE, SCHLOEDER-TEBALDI NANCY, HAO, ZHIMIN, ROCHAT, ALAIN, CLAUDE, SCHLOEDER-TEBALDI, NANCY
Applicants: CIBA SC HOLDING AG, CIBA SPECIALTY CHEMICALS HOLDING INC.
Application year: 1999
Main classification: C07D487
IPC codes: C07D487, C07D519, C08K5, C08L101, C09B57, C09B67