Concentrated mineralised natural complex for the integration of mineral oligoelements and methods for its production

Abstract: The invention concerns a highly concentrated mineralised natural complex, characterised by at least one main mineral element quantified with nutritional and/or dietetic integrator properties and by other mineral elements obtained in the complex from the mineralization of vegetal and/or animal products. Moreover, it concerns the method for its production consisting in using vegetal and/or animal organic substances, having a high content of oligominerals, in carrying out their fragmentation, their mixing and the mineralization until the inorganic part is completely separated from the organic part, and then in transforming the aforesaid inorganic part in forms of easy commercialisation.

Description: The invention concerns a concentrated mineralised natural complex and the method for its production, with respect to the integration of mineral oligoelements in pharmaceutical, cosmetic and herbal field. Currently, elements obtained by the purification of inorganic material, or, for example, through operations of synthesis, hemi-synthesis, chelation, complexation are being used as integrators of minerals oligoelements. The so obtained inorganic formulations present considerable problems of absorption and side effects. The ingested substances are thereby absorbed in a very little amount, consequently inducing the user to ingest considerable quantities, so that the absorbed ones can quantitatively satisfy the individual need. Another disadvantage of the products obtained with the known technique is the one due to the undesired side effects, for example, after the ingestion of substances used for integrating iron gastric disturbances may occur. An example of a mineral supplement is indicated in DATABASE WPI Section Ch, week 9621 Derwent Publications Ltd., London, GB; class D13, AN 96-205316 XP002063617 & JP 08 073213A it is obtained from coral sand dissolved in hydrochloric acid and after neutralising the acid it is heat treated in the furnace. MgO powder for food additives is obtained through this process. DATABASE WPI Section Ch, week 9209 Derwent Publications Ltd., London, GB; Class D16, AN 92-065215 XP002063616 & BR 9 003 291A indicates a process for the preparation of a stock culture containing ashes, which are the inorganic part of it, and both vegetable and animal organic matter. This product is deemed adequate to grow algae (Spirulina SPP) and contains mineral nutrients. The patent US-A-4915946 concerns a method which - starting off from bay salt and vegetable products such as Ginkgo, Persimmon, Pine and Bamboo and through a number of heating steps and fusions - obtains a final product that can be used in the field of medicine to treat cases of inflammation. It is known that some organic substances, such as some vegetable and/or animal products, contain oligominerals that are effective for man's health and simultaneously do not have negative side effects. However, those elements useful for man's health are contained in the above mentioned organic substances in very small percentages, hence they have poor therapeutic qualities. The aim of the present invention is on the one hand to produce concentrated mineralised natural complexes of one or more mineral elements which together predispose the human organism to their high absorption without producing negative side effects, on the other hand, the aim is to determine a process through which the mentioned complexes are realised. The process, related to this invention, which allows to reach such results, consists in resorting to natural substances, like vegetable or animal products, then, usually, in the carrying out of their mixing in definite proportions, therefore in their treatment until the inorganic part is separated from the organic one, and finally, in the transformation of the produced minerals blend into an easily administrated product, like capsules and tablets. For the consumer their intake is the equivalent to the intake of a quantity of minerals comparable in a qualitative and quantitative way to the ones that would be taken, in favourable cases, with the ingestion of an initial high quantity of vegetable or animal material. Moreover, the elaboration of organic natural products, among those containing an oligomineral mixture as close as possible to the wanted optimum, allows to obtain a mineral formulation that has a high biological affinity for man, with a greater bio-availability and compared with those that are nowadays on the market less harmful side effects. These formulation which for the complexity of the elements contained even in traces, cannot absolutely be chemically reconstructed. The invention through which such results have been reached, is realised on the one hand with natural concentrated mineralised complexes containing one or more mineral elements of vegetable or animal origin and a plurality of other elements equally useful to the human organism, and on the other hand with a process for their production realised through the mixing, in definite proportions, of the vegetal or animal products to be mineralised, and also with their mineralization through the elimination of the organic portion. Such process is, therefore, characterised by the treatment of natural organic products in order to obtain a mineralised complex containing all the mineral substances originally contained in the raw material treated first in form of oxides and other salts. Such mineralised complexes will be titrated in each element by considering those that are contained in a larger quantity, for example calcium, iron, zinc, potassium, copper, magnesium and manganese, and the aforesaid mineralised complexes will be finally checked to ascertain the absence of elements recognised as toxic, such as lead, cadmium and mercury. The mineralised natural complexes so produced permit to reach advantageous results, as described here below, unlike the use of single mineral elements obtained with methods known nowadays. In particular, they allow the organism to be integrated not only with the single primary elements, prevailing in the mineralised complex, but also with an innumerable series of other useful minerals that the mineralised complex contains in a composition which is formulated in nature. For instance, instead of assuming only "Gluconate Iron" as with the existing technique, the mineralised complex is taken as obtained from a mixture of vegetal products such as Capsella bursa pastoris, of which the upper part is used, Cynara of which the leaves are used, Salvia offinalis, of which the leaves are used. Such complex allows to intake iron in form of oxide and salts together with many other oligoelements, such as calcium, zinc, magnesium, potassium, sodium, copper and manganese, besides other ones in tiny traces, which aid the assimilation of iron without creating harmful side effects. The elaboration of natural organic products allows, that is to say, to produce a mineralised complex from which the human organism perfectly absorbs most of the various oligomineral elements contained in the same complex. The natural formula, possessing precise qualitative and quantitative relations of the single elements - probably due to biological affinity - determines a much greater absorption than the one obtained by ingesting the single elements presently used. Both the ratios between the single elements and the association between the single substances can be the cause of the considerable absorption of these last ones by the organism. In fact, many of the substances present in minimum doses, even if untraceable, act as catalysts, therefore helping the absorption of the primary element needed for the desired integration. An other advantage is due to the minor side effects resulting from the nature of the formulation more compatible with man. More characteristics of the invention will be evident from the following detailed description with reference to the process illustrated on the block diagram, provided only as example, in the enclosed drawing which shows in schematic form a flow diagram of the apparatus elements associated with performing the invention, and the steps of the invention. In the process exemplified in the drawing figure: 1 indicates the tank containing the mixture of vegetable and/or animal natural products, each one in a clean and fragmented state, containing one or more primary mineral elements in addition to those in smaller quantities, combined with organic substances to be eliminated ; 2 indicates the heated cell, normally at a temperature included between 200° and 900° C, in which the mixture coming from container 1 is mineralised, therefore the organic portion is normally separated in vapours and fumes. The mineralised complex in container 3 is a mineral complex characterised by a qualitative and quantitative composition of the chosen primary mineral elements, each one combined with a plurality of mineral elements already present, sometimes in minimum measures, on the vegetal or animal products from which they are originally produced and contained. The product coming out from group 3 is in one case conveyed directly to chamber 6, and in the other case conveyed to mixer 4 in which it is mixed with other active principles coming from container 5 in order to originate in chamber 6 the mixture that is to be transformed into capsules or tablets, then to be packed and after distributed on the market. In the general formulation the production process of a mineral complex first foresees the quantitative determination of the metals that one wishes to integrate, hence a selection of the vegetal or animal raw materials that are particularly rich in the above-mentioned metals. After having accomplished the choice of the organic raw materials to be used, the process through which the wanted mineral complex is obtained, can be described in a detailed way as follows : The chosen raw materials are analysed to make sure that the element which is to be integrated is constant in them. The selected raw materials are dried, then individually cut and sieved until obtaining a uniform granulometry that is adapted for being mineralised. The previously processed raw materials as described above, are eventually mixed between them in the right proportion in order to obtain in the final complex the content of mineral elements to be integrated as wanted in the ratio. The aforesaid mixture is distributed on trays of stainless steel until reaching a layer of 5 cm. for each tray. The trays are stacked in a muffle one on top of the others, with some space between them for combustion fumes to escape. The normally methane operating muffle is programmed in such a way to reach within it a temperature of approximately 200-400° C for 1-3 hours, then it is raised to a temperature of about 500-900° C for 3-5 more hours, or anyway until the complete removal of the organic portion from the mixture of drugs introduced. The first period of time, at a temperature of 200-400°C, is essential in order to obtain a perfect light coloured mineralised product, without any carbonised organic products. The mineralised product obtained from the muffle is subjected to a quantitative analysis for being titrated, at least in its mineral elements to be integrated, and to a control in order to verify the absence of elements recognised as toxic. It can be conveyed in the packaging division, or first mixed with additional chosen active principles, and hence sent to the packaging. However, the invention is illustrated here as follows with reference to two applications for the production of different concentrated mineralised natural complexes. Example 1 A mineral complex particularly rich in iron Drugs used : Capsella bursa pastoris, of which the upper part is used ; Cynara scolymus, of which the leaves are used ; Salvia officinalis, of which the leaves are used . The proportion for the mixing has been chosen according to the content of iron in the single drugs above-indicated, in particular : Capsella bursa pastoris : 20% Cynara scolymus : 70% Salvia officinalis : 10% The selected vegetal drugs have been cut until reaching a uniform granulometry that is adequate to be mineralised. The optimal granulometry is the following : Capsella bursa pastoris : 1.5 - 2.0 mm. Cynara scolymus : 1.5 - 2.0 mm. Salvia officinalis : 1.5 - 2.0 mm. The aforesaid fragmented mixture has been distributed on the stainless steel trays until reaching a layer of about 5 cm. of drug for each tray. The trays are stacked one on top of the other, with some space between them for the combustion fumes to escape. The methane operating muffle is programmed to reach within it a temperature of approximately 300° C for a time of 2 hours at first, then it is raised and kept at a temperature of approximately 700° C for 4 more hours. The first step at 300° C is essential in order to obtain a perfect white coloured final product completely inorganic. The mineralised product is encapsulated in gelatine capsules with a final weight of about 500 mg. . In this process the obtained mineralised complex contains all the mineral substances originally contained in the raw materials in form of oxides and other salts. The composition of the mineralised complex is the following : Element Concentration in the complex in mg/g Iron 7.73 Calcium 109.8 Zinc 0.19 Magnesium 21.75 Potassium 85.0 Sodium 9.3 Copper 0.03 Manganese 0.49 Due to the high concentration of iron and the relatively high specific weight of the mineralised complex, only four capsules a day are sufficient to obtain a good daily integration of such element (the daily recommended ration of iron is 14 mg. according to the Italian Law). As a matter of fact, the solubility, and therefore the bio-availability with a pH :1, is extremely high : in fact 2 g. of product are 93.05% soluble in one litre of hydrochloric acid with a pH:1 at 37° C (liquid simulating gastric juice). Example 2 A mineral complex particularly rich in calcium Drugs used : Paretaria officinalis, of which the upper part is used ; Urtica dioica, of which the leaves are used ; Eucalyptus globulus, of which the leaves are used ; Ginkgo biloba, of which the leaves are used . The proportions for the mixing have been chosen according to the calcium content in the single above-mentioned drugs, in particular : Paretaria officinalis : 10% Urtica dioica : 50% Eucalyptus globulus : 30% Ginkgo biloba : 10% The selected vegetable drugs have been cut until reaching a uniform granulometry, adequate for being mineralised. The optimal granulometry for each drug is the following : Paretaria officinalis 1.5 - 2.0 mm. Urtica dioica : 1.5 - 2.0 mm. Eucalyptus globulus : 1.5 - 2.0 mm. Ginkgo biloba : 1.5 - 2.0 mm. After having mixed the drugs, separately chopped up by following the above-mentioned granulometry, the mixture is distributed on steel trays until reaching a layer of 5 cm. of drug for each tray. The trays are stacked one on top of each other, with some space between them for the combustion fumes to escape. The muffle, normally heated with methane, is programmed in such a way to reach within it a temperature of approximately 300° C for 2 hours, then it is raised and kept at a temperature of about 700° C for 4 more hours. The first step at 300° C is essential in order to obtain a perfect white coloured final product and completely inorganic. The mineralised product is encapsulated in gelatine capsules with a final weight of about 500 mg. In this process the obtained mineralised complex contains all the mineral substances originally contained in the raw materials in form of oxides and other salts. The composition of the obtained mineralised complex is the following : Element Concentration in the complex in mg/g. Iron 1.9 Calcium 299.5 Zinc 0.46 Magnesium 33.74 Potassium 94.6 Sodium 8.5 Copper 2.5 Manganese 4.08 Due to the high concentration of calcium and the relatively high specific weight of the mineralised complex, only five capsules per day are sufficient to obtain a good daily integration of calcium (in Italy the recommended daily ration of calcium is of 800 mg.). In fact, the solubility, and so the bio-availability with a pH:1, is extremely high: 2 g. of product are 77.15% soluble in a litre of hydrochloric acid with a pH :1 at 37° C ( liquid simulating gastric juice). The process is repeated for any other individually chosen vegetal and/or animal product, or in combination with other organic products rich in metal or metals, through which the integration of mineral oligoelements in humans, animals or plants is intended to be operated.

Claims: A method for the production of concentrated mineralised natural complexes, to be used for the integration of mineral oligoelements in the pharmaceutical, herbal and cosmetic fields, characterised by the fact of using a plurality of organic starting materials of animal or vegetable origin including a mineral content, by the fact of determining the mineral content of the plurality of organic starting materials, by the fact of mixing said starting materials together to obtain a mixture having a mineral content corresponding to the product, and by the fact of removing organic material from the mixture to obtain the inorganic mineral concentrated product by heating at a temperature of 200° to 400° C for 1 to 3 hours, to obtain a light coloured inorganic product, followed by heating to a temperature of 500° to 900°C for 3 to 5 hours. The method for the production of concentrated mineralised natural complexes, as resulting from claim 1, characterised by the fact of comprising individually cutting and sieving the starting materials to obtain a uniform granulometry adapted for the mineralization. The method for the production of concentrated mineralised natural complexes, as resulting from claim 1, for the realisation of a mineralised complex particularly rich in iron (iron integrator), characterised by the fact that the starting organic substances are Capsella bursa pastoris (upper part) (20%), Cynara scolymus (leaves) (70%), Salvia officinalis (leaves) (10%), with the mineralization performed inside the methane heated muffle at a temperature of 300° C for two hours and at 700° C for four hours in order to originate a mineralised complex packed in capsules of which the iron content is equal to 7.73 mg/g. The method for the production of concentrated mineralised natural complexes, as resulting from claim 1, for the production of a mineralised complex particularly rich in calcium (calcium integrator), characterised by the fact that the starting organic substances are Paretaria officinalis (upper part) (10%), Urtica dioica (leaves) (50%), Eucalyptus globulus (leaves) (30%), Ginkgo biloba (leaves) (10%) and the mineralization is performed inside the methane heated muffle at a temperature of 300° C for two hours and of 700° C for four hours in order to originate a mineralised complex packed in gelatine capsules of which the calcium content is equal to 299.5 mg/g. A concentrated mineralised natural complex of vegetable and/or animal origin obtainable by the method according to claim 1.

Inventors: MERCATI VALENTINO, MERCATI, VALENTINO
Applicants: MERCATI V & C ABOCA SNC, ABOCA DI MERCATI VALENTINO & C. SOCIETA SEMPLICE
Application year: 1997
Main classification: A23L1
IPC codes: A61K36, A61K33, A23L1