7-Glycosyloxybenzopyran derivative and antiallergic agent containing the derivative as active ingredient

Abstract: A 7-glycosyloxybenzopyran derivative represented by the following formula (I) wherein, R₁ is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group, R₂ is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group and R₃ is a glycosyl group whose hydroxyl group is protected or not protected, selected from the group consisting of glucosyl, mannosyl and galactosyl groups, and physiologically acceptable salts thereof.

Description: FIELD OF THE INVENTION This invention relates to 7-glycosyloxybenzopyran derivatives which are obtained by glycosylation of the 7-position hydroxyl group of a benzopyran derivative with a hexose derivative. These compounds or physiologically acceptable salts thereof are useful as antiallergic agents. BACKGROUND OF THE INVENTION Benzopyran derivatives as the aglycon moiety of the7-glycosyloxybenzopyran derivatives of the present invention have been disclosed for example in EP-A-0598117 by the present inventors, and similar benzopyran derivatives for example in J. Med. Chem ., vol.31, pp. 1437-1445, 1988, by Donald T. Witiak and in U.S. Patent 4,845,121, but nothing about the 7-glycosyloxybenzopyran derivatives as their 7-position glycosides. In addition to this, nothing is known about the antiallergic activity of the 7-glycosyloxybenzopyran derivatives of the present invention and physiologically acceptable salts thereof. Since antiallergic agents so far available commercially are not satisfactory in terms of efficiency, safety and bioavailability, studies on the development of antiallergic agents have been carried out extensively. For example, a typical antiallergic agent, Tranilast (general name), requires high-dose administration for care of allergic disease, though its acute toxicity value (LD 50 ) in mice is low (780 mg/kg), hence causing a problem of requiring caution at the time of its use because of the closeness between quantities of its efficacy and toxicity, namely its narrow safety range. Also, Disodium Cromoglicate (general name) as a well known antiasthamtic agent whose efficacy has been confirmed clinically is satisfactory in terms of its toxicity, but must be used by spray inhalation due to its extremely poor gastrointestinal absorbability. In addition, these known antiallergic agents are not effective on delayed type allergy, though they are effective on immediate type allergy. Chronic state of allergic diseases including asthma and atopic dermatitis is a serious problem, and the delayed type allergy is deeply concerned in the development of the chronic state. In consequence, a drug which is effective on both immediate type allergy and delayed type allergy is desirable as an antiallergic agent. As it is universally known, steroid is effective on both immediate type allergy and delayed type allergy but cause extremely serious side effects. As has been described above, most of the antiallergic agents so far reported have various disadvantages, because they cannot show sufficient therapeutic effect because of the lack of efficacy on delayed type allergy, they are low in safety due to their narrow safety range, or their administration method is limited because of their poor gastrointestinal absorbability. In consequence, great concern has been directed toward the development of a drug which can be used in oral administration, has low toxicity and is effective on both immediate and delayed type allergies. The inventors of the present invention have provided, by EP-A-0598117, a benzopyran derivative and an antiallergy agent which comprises the derivative as an active ingredient. This time, taking the aforementioned problems involved in the prior art into consideration, we contemplate providing a novel substance more useful as a drug and an antiallergic agent having low toxicity and excellent effect. SUMMARY OF THE INVENTION With the aim of providing a compound more useful as a drug, the inventors of the present invention have synthesized various glycosylated compounds of the benzopyran derivative disclosed in EP-A-0598117 by glycosylating its 7-position hydroxyl group with a hexose derivative and examined their antiallergic activity and safety. As the result, the present inventors have found that a 7-glycosyloxybenzopyran derivative represented by the following formula (I) is capable of showing markedly excellent antiallergic activity with low toxicity. The present invention has been accomplished on the basis of this finding. Accordingly, the present invention relates to a 7-glycosyloxybenzopyran derivative represented by the following formula (I) wherein R 1 is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group, R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group and R 3 is a glycosyl group whose hydroxyl group is protected or not protected, selected from the group consisting of glucosyl, mannosyl and galactosyl groups, to physiologically acceptable salts thereof and to an antiallergic agent which comprises the 7-glycosyloxybenzopyran derivative represented by the above formula (I) or a physiologically acceptable salt thereof as an active ingredient. DETAILED DESCRIPTION OF THE INVENTION Firstly, the 7-glycosyloxybenzopyran derivative represented by the formula (I) is described. In the formula (I) of the present invention, R 1 is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group. Illustrative examples of the acyl group include alkanoyl groups such as acetyl, propionyl, butylyl, isobutylyl and the like groups, aroyl groups such as benzoyl group or a benzoyl group which may have a substituent group (p-methoxybenzoyl, p-methylbenzoyl, p-chlorobenzoyl or p-nitrobenzoyl for instance) and the like and acyl groups such as an alkoxycarbonyl group (methoxycarbonyl or ethoxycarbonyl for instance) and the like, of which an alkanoyl group is preferred and an acetyl group is particularly preferred. Illustrative examples of the alkyl group include straight- or branched-chain noncyclic alkyl groups such as methyl, ethyl, propyl, isopropyl, n-butyl, s-butyl, t-butyl, n-pentyl, 2-methylpentyl, hexyl, octyl, decyl, dodecyl and the like alkyl groups preferably having 1 to 12, more preferably 1 to 10, carbon atoms. Illustrative examples of the cycloalkyl group include straight- or branched-chain cycloalkyl groups such as unsubstituted cycloalkyl groups such as cyclopropyl, cyclopentyl, cyclohexyl and cyclooctyl, and cycloalkyl groups substituted with alkyl groups such as 4-methylcyclohexyl and dimethylcyclohexyl, and the like, of which a cycloalkyl group having 5 to 8 of total number of carbon atoms of ring and side chain is preferred, and 4-methylcyclohexyl is particularly preferred. Illustrative examples of the alkenyl group include straight- or branched-chain alkenyl groups such as vinyl, propenyl, pentenyl, hexenyl, heptenyl, octenyl, nonyl, decenyl, 3-methyl-2-butenyl, geranyl and the like alkenyl groups preferably having 2 to 10, more preferably 6 to 10, carbon atoms. Illustrative examples of the aralkyl group include those to be used as hydroxyl group protecting groups such as benzyl group or a benzyl group which may have a substituent group (p-methoxybenzyl, p-methylbenzyl, p-chlorobenzyl or p-nitrobenzyl for instance) and the like, of which unsubstituted benzyl group is particularly preferred. In the formula (I) of the present invention, R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group. Illustrative examples of the alkyl group include straight- or branched-chain alkyl groups such as methyl, ethyl, propyl, isopropyl, n-butyl, s-butyl, t-butyl, n-pentyl, 2-methylpentyl, hexyl, octyl, decyl, dodecyl and the like alkyl groups preferably having 1 to 12, more preferably 1 to 10, carbon atoms. Illustrative examples of the cycloalkyl group include straight- or branched-chain cycloalkyl groups such as unsubstituted cycloalkyl groups such as cyclopropyl, cyclopentyl, cyclohexyl and cyclooctyl, and cycloalkyl groups substituted with alkyl groups such as 4-methylcyclohexyl and dimethylcyclohexyl, and the like, of which a cycloalkyl group having 5 to 8 of total number of carbon atoms of ring and side chain is preferred, and 4-methylcyclohexyl is particularly preferred. Illustrative examples of the alkenyl group include straight- or branched-chain alkenyl groups such as vinyl, propenyl, pentenyl, hexenyl, heptenyl, octenyl, nonyl, decenyl, 3-methyl-2-butenyl, geranyl and the like alkenyl groups preferably having 2 to 10, more preferably 6 to 10, carbon atoms. Illustrative examples of the aralkyl group include those to be used as hydroxyl group protecting groups such as benzyl group or a benzyl group which may have a substituent group (p-methoxybenzyl, p-methylbenzyl, p-chlorobenzyl or p-nitrobenzyl for instance) and the like, of which unsubstituted benzyl group is particularly preferred. The glycosyl group represented by R 3 in the fourmula (I) is selected from glucosyl, mannosyl and galactosyl groups whose all or part of hydroxyl groups, which relates to binding of glycosyl group, may or may not be protected with a protecting group. In general, saccharides are known to have D and L stereoisomers which are also included in the present invention. The hexose derivatives to be used as the material of glycosyl groups are glucose, mannose and galactose whose all or part of hydroxyl groups may or may not be protected with a protecting group, of which an unprotected glycosyl group is preferred. The compound of the present invention, 7-glycosyloxybenzopyran derivative, is a compound in which any of these hexose derivatives is linked to the 7-position of a benzopyran derivative through glycoside bonding. Such a glycoside bonding may include α- and β-binding types, and both of these binding types are included in the 7-glycosyloxybenzopyran derivative of the present invention. With regard to the glycosyl group which is protected with a protecting group, preferred examples of the protecting group include those usually used as saccharide protecting groups such as acyl, aralkyl and the like groups. In this case, illustrative examples of the acyl group include alkanoyl groups such as acetyl, propionyl, butylyl, isobutylyl and the like groups, aroyl groups such as benzoyl group or a benzoyl group which may have a substituent group (p-methoxybenzoyl, p-methylbenzoyl, p-chlorobenzoyl or p-nitrobenzoyl for instance) and the like and an alkoxycarbonyl group (methoxycarbonyl or ethoxycarbonyl for instance) and the like, of which an alkanoyl group is particularly preferred. Illustrative examples of the aralkyl group include a benzyl group or a benzyl group which may have a substituent group (p-methoxybenzyl, p-methylbenzyl, p-chlorobenzyl or p-nitrobenzyl for instance) and the like. Preferable protecting groups are a benzyl group and acetyl group, of which an acetyl group is particularly preferred. Though it varies depending on the type of the substituent groups of R 1 and R 2 , galactose may be used as most preferred glycosyl group, followed by glucose and mannose in that order. Also, an unprotected glycosyl group is more preferable than its protected counterpart. From the viewpoint of antiallergic activity, preferred examples of the 7-glycosyloxybenzopyran derivative of the present invention include a compound in which R 1 is a hydrogen atom, an alkyl group, a cycloalkyl group or an alkenyl group, R 2 is a hydrogen atom, an alkyl group, a cycloalkyl gorup or an alkenyl group and R 3 is glucosyl, mannosyl or galactosyl group, more preferred examples include a compound in which R 1 is an alkyl group, a cycloalkyl group or an alkenyl group, R 2 is a hydrogen atom and R 3 is glucosyl, mannosyl or galactosyl group, most preferred examples include a compound in which R 1 is an alkyl group, R 2 is a hydrogen atom and R 3 is glucosyl group, a compound in which R 1 is a cycloalkyl group, R 2 is a hydrogen atom and R 3 is glucosyl group, a compound in which R 1 is an alkenyl group, R 2 is a hydrogen atom and R 3 is glucosyl group, a compound in which R 1 is an alkyl group, R 2 is a hydrogen atom and R 3 is galactosyl group, a compound in which R 1 is a cycloalkyl group, R 2 is a hydrogen atom and R 3 is galactosyl group, and a compound in which R 1 is an alkenyl group, R 2 is hydrogen atom and R 3 is galactosyl group. The following summarizes a process for the production of the 7-glycosyloxybenzopyran derivative of the present invention. The 7-glycosyloxybenzopyran derivative of the present invention represented by the formula (I) can be produced for example in the following manner in accordance with the following reaction scheme: wherein, R 1 , R 2 and R 3 are the same meanings as defined above, R 4 represents an acyl group or an aralkyl group which is a protecting group of hydroxyl group of hexose derivative, and X represents a halogen atom. As a first step, 7-hydroxybenzopyran derivative (1) disclosed by the present inventors in a prior application (EP-A-0598117) and a hexose halide derivative represented by the formula (2) are subjected to glycosylation. Each of the hexose halide derivatives can be prepared in accordance with a known method (cf. L.J. Haynes and F.H. Newth, Adv. Carbohydr. Chem. , 10, 207 (1955); W. Korytnyk and J.A. Mills, J. Chem. Soc. , 1959, 636). A process for the production of the benzopyran derivative (1) to be used herein as a starting material is described in detail in EP-A-0598117. Namely, this derivative can be produced in accordance with the following reaction scheme: Firstly, hydroxyl group of 2,4-dihydroxyacetophenone (a) is protected with benzyl group to obtain a compound (b). Next, carbon atoms of the thus obtained compound are increased by its reaction with dimethyl carbonate to convert it into a keto ester compound (c) which is subsequently allowed to react with benzoyl peroxide to obtain a compound (d). At this stage, the benzyl group used as a hydroxyl group protecting group is deblocked by hydrocracking and then treated with an acid to obtain a benzoyloxy compound (e). The thus obtained benzoyloxy compound (e) is then treated with a metal alkoxide in a non-aqueous system to effect elimination of benzoyl group, thereby obtaining a benzopyran derivative (f). Benzopyran derivative (1) wherien R 1 is other acyl group than benzoyl group is synthesized as follows. The hydroxyl groups at the 3-position and the 7-position of benzopyran derivative (f) are acylated and then the acyl group at the 7-position is selectively eliminated, whereby obtaining 7-hydroxy compound. Benzopyran derivative (1) wherein the 4-position is substituted with an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group is synthesized as follows. The thus obtained benzopyran derivative (f) wherien the hydroxyl groups at the 3-position and the7-position are protected is subjected to alkylation, cycloalkylation, alkenylation or aralkylation of the hydroxyl group at the 4-position. Benzopyran derivative (1) wherein the 3-position is substituted with an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl gorup is synthesized by selective elimination of the acyl group at the 3-position followed by alkylation, cycloalkylation, alkenylation or aralkylation. Benzopyran derivative (1) can be obtained by selectively introducing substituents. Using the thus obtained benzopyran derivative (1) and the hexose derivative (2), glycosylation of the 7-position hydroxyl group is carried out in accordance with the known Koenigs-Knorr method. In this glycosylation, a metal catalyst may be used in the known Koenigs-Knorr method in order to accelerate the reaction, such as a silver salt, preferably silver oxide, silver carbonate or the like. In this reaction, an organic solvent is used as a reaction solvent. Preferred examples of the solvent include ether solvents such as diethyl ether, tetrahydrofuran, dimethoxyethane, dioxane and the like, amide solvents such as dimethylformamide, dimethylacetamide and the like and nitrile solvents such as acetonitrile, propionitrile and the like. The reaction may be carried out at a temperature of from -20 to 50°C, preferably from 0 to 30°C, for a period of generally from 1 to 30 hours. In this way, the 7-glycosyloxybenzopyran derivative of the formula (3) is obtained. When a compound having unprotected hydroxyl group on its glycosyl group is synthesized, deblocking reaction is carried out as a second step by debenzylation or deacylation of the hexose moiety in the formula (3), which can be attained in the usual way. That is, in the case of debenzylation, the reaction is effected by hydrocracking in an atmosphere of hydrogen gas making use of a metal catalyst. Examples of the metal catalyst include palladium, platinum and the like catalysts which may be used in an amount of from 1 to 10% by weight based on the compound represented by the formula (3). The reaction in hydrogen gas may be carried out under a pressurized condition or under normal pressure. The reaction may be carried out generally in a solvent. Preferred examples of the solvent include alcohol solvents such as methanol, ethanol, propanol, butanol and the like, ether solvents such as diethyl ether, tetrahydrofuran, dioxane and the like and acetic ester solvents such as methyl acetate, ethyl acetate, propyl acetate and the like. The reaction may be carried out at a temperature of from - 10 to 50°C, preferably from 0 to 30°C, for a period of generally from 1 to 5 hours. Also, deacylation can be effected by allowing the compound to react with a base as a deacylation agent which may be selected from hydroxides such as sodium hydroxide, potassium hydroxide, lithium hydroxide and the like and alkolate bases such as sodium methoxide, potassium methoxide, sodium ethoxide, potassium ethoxide and the like. Preferred examples of the reaction solvent to be used in this reaction include lower alcohols such as methanol, ethanol, propanol and the like, ether solvents such as diethyl ether, tetrahydrofuran, dimethoxyethane, dioxane and the like and amide solvents such as dimethylformamide, dimethylacetamide and the like. The reaction temperature varies depending on the reaction reagent and solvent to be used and is within the range of preferably from -10 to 50°C, more preferably from 0 to 30°C. The reaction time is generally from 1 to 5 hours. The following compounds are illustrative examples of the thus obtained 7-glycosyloxybenzopyran derivatives of the present invention. 3,4-dihydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one3-acetoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one3-isopropoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-octyIoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyolohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one3-undecanyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one3-decanyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-axetoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dihydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-hydroxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-methoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-ethoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-isopropoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-butoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hexyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-octyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-decanyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-undecanyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-cyclohexyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(cis-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(trans-4-methylcyclohexyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(3-hexenyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-geranyloxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3,4-dibenzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-(p-methoxybenzyloxy)-4-benzyloxy-7-(tetra-O-benzyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-methoxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-ethoxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-isopropoxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-butoxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-hexyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-octyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-decanyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-undecanyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-cyclohexyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(cis-4-methylcyclohexyloxy)-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(trans-4-methylcyclohexyloxy)-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(3-hexenyloxy)-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one3-hydroxy-4-geranyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(p-methoxybenzyloxy)-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-cyclohexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(cis-4-methylcyclohexyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(trans-4-methylcyclohexyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-methoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-ethoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-butoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-octyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-decanyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-undecanyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-methoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-ethoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-octyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-benzoyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-methoxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-ethoxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-isopropoxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one3-hydroxy-4-butoxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-hexyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-octyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-decanyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-undecanyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-cyclohexyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(cis-4-methylcyclohexyloxy)-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(trans-4-methylcyclohexyloxy)-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(3-hexenyloxy)-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-geranyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(p-methoxybenzyloxy)-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-cyclohexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(cis-4-methylcyclohexyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(trans-4-methylcyclohexyloxy)-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-methoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-ethoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-isopropoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-butoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-octyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-decanyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-undecanyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-geranyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-methoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-ethoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-isopropoxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-octyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-geranyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-benzoyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-methoxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-ethoxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-isopropoxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-butoxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-hexyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-octyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-decanyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-undecanyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-cyclohexyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(cis-4-methylcyclohexyloxy)-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(trans-4-methylcyclohexyloxy)-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(3-hexenyloxy)-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-geranyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-benzyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-hydroxy-4-(p-methoxybenzyloxy)-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-cyclohexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(cis-4-methylcyclohexyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(trans-4-methylcyclohexyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-methoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-ethoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-octyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-decanyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-undecanyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-benzoyloxy-4-(p-methoxybenzyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-methoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-ethoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-isopropoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-octyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-(3-hexenyloxy)-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-propionyloxy-4-geranyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-methoxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-ethoxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-isopropoxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-butoxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-hexyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-octyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-decanyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-undecanyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(3-hexenyloxy)-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-geranyloxy-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one 3-acetoxy-4-(p-methoxybenzyloxy)-7-(tetra-O-benzoyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one Physiologically acceptable salts of these compounds are also included in the illustrative examples. The term "physiologically acceptable salts" as used herein means nontoxic alkali addition salts of, for example, the compounds cited above, which include sodium salts, potassium salts, magnesium salts, calcium salts, ammonium salts, nontoxic amine salts and the like. These physiologically acceptable salts can be produced by known methods and are also included in the present invention. Since the 7-glycosyloxybenzopyran derivatives and physiologically acceptable salts thereof of the present invention (to be referred to as "the compound of the present invention" hereinafter) have a function to inhibit both immediate and delayed type allergic reactions as will be described later in Examples, they are useful as antiallergic agents for the treatment or prevention of various allergic diseases. The term "allergic diseases" as used herein means allergic diseases resulting from excess activation of the biological immune mechanism caused by extrinsic or intrinsic antigens, which include immediate type asthma, delayed type asthma, bronchial asthma, pediatric asthma, atopic dermatitis, allergic dermatitis, urticaria, eczema, allergic conjunctivitis, allergic rhinitis, hay fever, food allergy, allergic gastroenteritis, allergic colitis, drug allergy, contact dermatitis, autoimmune disease and the like. The antiallergic agent which comprises the compound of the present invention as an active ingredient can be administered orally or parenterally (for example, intravenous injection, subcutaneous injection, percutaneous absorption, rectal administration or the like). Such a pharmaceutical agent can be made into various dosage forms according to the purpose, such as tablets, capsules, granules, fine subtilaes, powders, troches sublingual tablets, suppositories, ointments, injections, emulsions, suspensions, medicated syrups and the like. These dosage forms can be prepared in accordance with known techniques making use of pharmaceutically acceptable carriers which are commonly used in this type of drugs, such as excipients, bonding agents, disintegrators, lubricants, preservatives, anti-oxidative agents, isotonic agents, buffering agents, coating agents, sweetening agents, dissolving agents, bases, dispersing agents, stabilizing agents, coloring agents and the like. Illustrative examples of these pharmaceutically acceptable carriers are listed in the following. Firstly, as excipients, the following can be listed: starch and derivatives of starch (such as dextrin, carboxymethyl starch and the like), cellulose and derivatives of cellulose (such as methylcellulose, hydroxypropylmethylcellulose and the like), sugars (such as lactose, sucrose, glucose and the like), silicic acid and silicates (such as naturally occurring aluminum silicate, magnesium silicate and the like), carbonates (such as calcium carbonate, magnesium carbonate, sodium hydrogencarbonate and the like), aluminum magnesium hydroxide, synthetic hydrotalcite, polyoxyethylene derivatives, glycerin monostearate, sorbitan monooleic acid and the like. As bonding agents, the following can be listed: starch and starch derivatives (such as alpha starches, dextrin and the like), cellulose and derivatives of cellulose (such as ethyl cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose and the like), gum arabic, traganth, gelatin, sugars (such as glucose, sucrose and the like), ethanol, polyvinyl alcohols and the like. As disintegrators, the following can be listed: starch and starch derivatives (such as carboxymethyl starch, hydroxypropyl starch and the like), cellulose and cellulose derivatives (such as sodium carboxymethyl cellulose, crystal cellulose, hydroxypropylmethyl cellulose and the like), carbonates (such as calcium carbonate, calcium hydrogencarbonate and the like), traganth, gelatins, agar and the like. As lubricants, the following can be listed: stearic acid, calcium stearate, magnesium stearate, talc, silicic acid and its salts (such as light silicic anhydrides, naturally occurring aluminum silicates and the like), titanium oxide, calcium hydrogen phosphate, dry aluminum hydroxide gel, macrogol and the like. As preservatives, the following can be listed: p-hydroxybenzoates, sulfites (such as sodium sulfites, sodium pyrosulfites and the like), phosphates (such as sodium phosphates, calcium polyphosphates, sodium polyphosphates, sodium methaphosphate and the like), alcohols (such as chlorobutanol, benzyl alcohol and the like), benzalkonium chloride, benzethonium chloride, phenol, cresol, chlorocresol, dihydroacetic acid, sodium dihydroacetate, glycerin sorbic acid, sugars and the like. As anti-oxidative agents, the following can be listed: sulfites (such as sodium sulfite, sodium hydrogen sulfite and the like), rongalite, erythorbic acid, L-ascorbic acid, cysteine, thioglycerol, butylhydroxyanisol, dibutylhydroxytoluene, propylgallic acid, ascorbyl palmitate, dl-α-tocopherol and the like. As isotonic agents, the following can be listed: sodium chloride, sodium nitrate, potassium nitrate, dextrin, glycerin, glucose and the like. As buffering agents, the following can be listed: sodium carbonate, hydrochloric acid, boric acid, phosphates (such as sodium hydrogenphosphate) and the like. As coating agents, the following can be listed: cellulose derivatives (such as hydroxypropyl cellulose, cellulose acetate phthalate, hydroxypropylmethyl cellulose phthalate and the like), shellac, polyvinylpyrrolidone, polyvinylpyridines (such as poly-2-vinylpyridine, poly-2-vinyl-5-ethylpyridine and the like), polyvinylacetyl diethylaminoacetate, polyvinyl alcohol phthalate, methacrylate, methacrylate copolymers and the like. As sweetening agents, the following can be listed: sugars (such as glucose, sucrose, lactose and the like), sodium saccharin, sugar alcohols and the like. As dissolving agents, the following can be listed: ethylenediamine, nicotinamide, sodium saccharin, citric acid, citrates, sodium benzoic acid, soaps, polyvinylpyrrolidone, polysolvates, sorbitan fatty acid esters, glycerin, propylene glycol, benzyl alcohols and the like. As bases, the following can be listed: fats (such as lard and the like), vegetable oils (such as olive oil, sesame oil and the like), animal oil, lanolin acid, petrolatums, paraffin, wax, resins, bentonite, glycerin, glycol oils, higher alcohols (such as stearyl alcohol, cetanol) and the like. As dispersing agents, the following can be listed: gum arabic, traganth, cellulose derivatives (such as methyl cellulose and the like), stearic acid polyesters, sorbitan sesquioleate, aluminum monostearate, sodium alginate, polysolvates, sorbitan fatty acid esters and the like. Lastly, as stabilizing agents, the following can be listed: sulfites (such as sodium hydrogen sulfite and the like), nitrogen, carbon dioxide and the like. Though the content of the compound of the present invention in these pharmaceutical preparations varies depending on the dosage forms, it may be contained preferably in a concentration of from 0.01 to 100% by weight. Dose of the antiallergic agent of the present invention can be varied over a broad range depending on each mammal including human, mouse, rat, pig and the like, to be treated, extent of each disease, doctor's judgement and the like. In general, however, it may be administered in a dose of from 0.01 to 200 mg, preferably from 0.01 to 50 mg, more preferably from 0.05 to 10 mg, as the active ingredient per day per kg body weight in the case of oral administration or in a dose of from 0.01 to 10 mg, preferably from 0.01 to 5 mg, as the active ingredient per day per kg body weight in the case of parenteral administration. The daily dose described above may be used in one portion or in divided portions and changed optionally in accordance with the extent of diseases and doctor's judgement. The following examples are intended to illustrate the preparation of the compounds of this invention and the pharmaceutical compositions of these compounds; however these examples are intended to illustrate the invention and not to be construed to limit the scope of the invention. REFERENCE EXAMPLE 1 3-methoxy-4-benzyloxy-7-acetoxy-2H-1-benzopyran-2-one To a mixture of 8.11 g of 3-methoxy-4-hydroxy-7-acetoxy-2H-1-benzopyran-2-one (27.8 mmol) and 5.71 g of benzyl bromide (33.4mmol) in 50 ml of DMF was added 4.61 g of sodium carbonate (33.4 mmol) under argon atmosphere, then the mixture was stirred at 50 ° for 2 hours. The solid in the reaction mixture was filtered off, the filtrate was poured into 200 ml of water and extracted with 500 ml of benzene. The organic layler was concentrated in vacuo after drying over magnesium sulfate to give oily residue. The residue was purified on silica gel column chromatography (eluent: benzene/ethyl acetate=7/3) to give 3.50 g of the title compound. (yield=33 %) 1 H-NMR (CDCl 3 , δ-TMS) : 7.67 (d, 1H, J=8.8 Hz), 7.40 (m, 5H), 6.82 (d, 1H, J=8.8 Hz), 6.78 (s, 1H), 5.45 (s, 2H), 3.85 (s, 3H), 2.32 (s, 3H) IR (KBr, cm -1 ) : 1760, 1720, 1620, 1435, 1360, 1220 Elemental analysis for C 19 H 16 O 6 Calculated (%) C 67.05 H 4.75 O 28.20 Found (%) C 67.15 H 4.63 O 28.22 REFERENCE EXAMPLE 2 3-methoxy-7-hydroxy-4-benzyloxy-2H-1-benzopyran-2-one To a mixture of 3.64 g of 3-methoxy-4-benzyloxy-7-acetoxy-2H-1-benzopyran-2-one (10.7 mmol) in 50 ml of methanol was added 0.58 g of sodium methoxide (10.7 mmol) and the mixture was stirred at room temperature for 1 hour. Then 2.31 g of Amberlyst-15 (Trademark : Organo corp.) was added, and the mixture was stirred at room temperature for 1 hour. Amberlyst-15 was filterd off, the filtrate was concentrated under reduced pressure. The precipitate was obtained during concentration and filtered to give 2.59 g of the title compound. (yield=77 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.30 (bs, 1H), 7.67 (d, 1H, J=8.8 Hz), 7.40 (m, 5H), 6.72 (d, 1H, J=8.8 Hz), 6.78 (s, 1H), 5.45 (s, 2H), 3.78 (s, 3H) IR (KBr, cm -1 ) : 3200, 1760, 1720, 1620, 1435, 1360, 1220 Elemental analysis for C 17 H 14 O 5 Calculated (%) C 68.45 H 4.73 O 26.82 Found (%) C 68.25 H 4.73 O 27.02 REFERENCE EXAMPLE 3 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one To a mixture of 17.31 g of 4-butoxy-3, 7-diacetoxy-2H-1-benzopyran-2-one (51.79 mmol) in 170 ml of methanol was added 2.66 g of sodium methoxide (49.20 mmol) and the reaction mixture was stirred at room temperature for 3 hours. Then 22.36 g of Amberlyst-15 was added, and the mixture was stirred at room temperature for 1 hour. Amberlyst-15 was filtered off and the filtrate was concentrated under reduced pressure to give a crystalline product. The product was reprecipitated from tertahydrofuran and hexane to give 12.87 g of the title compound. (yield=85 %) 1 H -NMR (DMSO-d 6 , δ-TMS): 10.60 (s, 1H), 7.64 (d, 1H, J=8.8Hz), 6.87 (dd, 1H, J=2.4Hz, J=8.8Hz), 6.75 (d, 1H, J=2.4Hz), 4.42 (t, 2H, J=6.2Hz), 2.33 (s,3H), 1.80∼1.70 (m, 2H), 1.55∼1.40 (m, 2H), 0.94 (t, 3H, J=7.4Hz) IR (KBr, cm -1 ) : 3200, 2950, 1760,1690, 1620, 1410, 1340 Elemental analysis for C 15 H 16 O 6 Calculated (%) C 61.64 H 5.52 O 32.84 Found (%) C 61.60 H 5.53 O 32.87 REFERENCE EXAMPLE 4 3-acetoxy-4-hexyloxy-7-hydroxy-2H-1-benzopyran-2-one In accordance with Reference Example 3, 30.00 g of 4-hexyloxy-3, 7-diacetoxy-2H-1-benzopyran-2-one (82.79 mmol) was used instead of 4-butoxy-3, 7-diacetoxy-2H-1-benzopyran-2-one, 22.01 g of the title compound was obtained. (yield=83 %) 1 H -NMR (DMSO-d 6 , δ-TMS): 10.63 (s, 1H), 7.63 (d, 1H, J=8.8Hz), 6.86 (dd, 1H, J=2.4Hz, J=8.8Hz), 6.74 (d, 1H, J=2.4Hz), 4.41 (t, 2H, J=6.2Hz), 2.32 (s,3H), 1.80∼1.70 (m, 2H), 1.50∼1.25 (m, 4H), 0.87 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3200, 2930, 1760, 1690, 1620, 1410, 1340 Elemental analysis for C 17 H 20 O 6 Calculated (%) C 63.74 H 6.29 O 29.97 Found (%) C 63.76 H 6.26 O 29.98 REFERENCE EXAMPLE 5 3-acetoxy-4-octyloxy-7-hydroxy-2H-1-benzopyran-2-one In accordance with Reference Example 3, 30.00 g of 4-octyloxy-3, 7-diacetoxy-2H-1-benzopyran-2-one (76.84 mmol) was used instead of 4-butoxy-3, 7-diacetoxy-2H-1-benzopyran-2-one, 23.19 g of the title compound was obtained. (yield=87 %) 1 H -NMR (DMSO-d 6 , δ-TMS): 10.62 (s, 1H), 7.63 (d, 1H, J=8.8Hz), 6.86 (dd, 1H, J=2.4Hz, J=8.8Hz), 6.74 (d, 1H, J=2.4Hz), 4.46 (t, 2H, J=6.4Hz), 2.32 (s,3H), 1.80∼1.65 (m, 2H), 1.50∼1.10 (m, 6H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3200, 2900, 1760, 1690, 1620, 1410, 1340 Elemental analysis for C 19 H 24 O 6 Calculated (%) C 65.50 H 6.94 O 27.55 Found (%) C 65.38 H 6.98 O 27.64 EXAMPLE 1 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 1) 1.53 g of 3-methoxy-4-benzyloxy-7-hydroxy-2H-1-benzopyran-2-one (5.12 mmol) and 4.21 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyl bromide (10.23 mmol) were dissolved in 20 ml of acetonitrile at room temperature under argon atmosphere. To this solution, 1.19 g of silver (I) oxide (5.12 mmol) and 13.77 g of molecular sieve 4A Merck were added and the mixture was stirred at room temperature for 2 hours. After filtration, the filtrate was concentrated under reduced pressure, giving an oily residue. Purification of the residue on silica gel column chromatography ( eluent : benzene/ethyl acetate= 2/1) gave 1.77 g of the title compound (1). (yield=55 %) 1 H -NMR (CDCl 3 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.20∼7.40 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.25∼5.35 (m, 2H), 5.14 (t, 1H, J=8.0Hz), 4.93 (d, 1H, J=8.0Hz), 4.21∼4.28 (m, 2H), 3.82∼3.85 (m, 1H), 3.78 (s, 3H), 2.02∼2.22 (m, 12H) IR (KBr, cm -1 ) : 1750, 1620, 1435, 1360, 1240 Elemental analysis for C 31 H 32 O 14 Calculated (%) C 59.23 H 5.09 O 35.68 Found (%) C 59.40 H 4.95 O 35.65 EXAMPLE 2 3-methoxy-4-hydroxy-7-(tetra-O-acety-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 2) Under hydrogen atmosphere, a mixture of 2.19 g of 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (3.48 mmol) and 0.22 g of 10 % palladium on activated carbon in 20 ml of ethyl acetate was stirred at room temperature for 2 hours. The catalyst was filtered off, and the filtrate was evaporated to give a crude product. After washing the crude product with diethyl ether, 1.59 g of the title compound (2) was obtained. (yield=85 %) 1 H -NMR (CDCl 3 , δ-TMS) : 10.50 (bs, 1H), 7.70 (d, 1H, J=8.8Hz), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.25∼5.35 (m, 2H), 5.14 (t, 1H, J=8.0Hz), 4.93 (d, 1H, J=8.0Hz), 4.21∼4.28 (m, 2H), 3.82∼3.85 (m, 1H), 3.78 (s, 3H), 2.02∼2.22 (m, 12H) IR (KBr, cm -1 ) : 3250, 1750, 1620, 1435, 1360, 1240 Elemental analysis for C 24 H 26 O 14 Calculated (%) C 53.53 H 4.83 O 41.64 Found (%) C 53.40 H 4.90 O 41.70 EXAMPLE 3 3-methoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 3) Under argon atmosphere, to a mixture of 0.58 g 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (1.07 mmol) in 12 ml of methanol was added 0.15 g of sodium methoxide at 5 ° and followed by stirring at room temperature for 1 hour. Then 0.75 g of Ambrtlyst-15 was added and the mixture was stirred at room temperature for 1 hour. After dissolving a precipitate generated during neutralization by adding excess methanol, Amberlyst-15 was filtered off and the filtrate was concentrated in vacuo to give a precipitate. Filtration gave 0.31 g of the title compound (3). (yield=77 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 11.40 (bs, 1H), 7.67 (d, 1H, J=8.4Hz), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 4.98 (bs, 4H), 4.83 (d, 1H, J=7.6Hz), 3.85 (s, 3H), 3.65 (d, 1H, J=7.6Hz), 3.51 (d, 1H, J=7.6Hz), 3.41 (m, 1H), 3.31∼3.20 (m, 3H) IR (KBr, cm -1 ) : 3350, 1660, 1630, 1580, 1270 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.52 H 4.85 O 43.63 EXAMPLE 4 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one(compound 4) In accordance with Example 1, 4.21 g of 2, 3, 4, 6-tetra-O-acetyl-β-D-manno-pyranosyl bromide (10.23 mmol) was used instead of 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyl bromide, 1.88 g of the title compound (4) was obtained. (yield=58 %) 1 H -NMR (CDCl 3 , δ-TMS) : 7.67 (d, 1H, J=8.4Hz), 7.20∼7.40 (m, 5H), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 6.00 (s, 1H), 5.55 (m, 2H), 5.45 (s, 2H), 5.40 (m, 1H), 4.23 (m, 2H), 4.15 (s, 1H), 3.75(s, 3H), 2.02∼2.22 (m, 12H) IR (KBr, cm -1 ) : 1750, 1620, 1435, 1360, 1240 Elemental analysis for C 31 H 32 O 14 Calculated (%) C 59.23 H 5.09 O 35.68 Found (%) C 59.40 H 5.15 O 35.45 EXAMPLE 5 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 5) In accordance with Example 1, 4.21 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-galacto-pyranosyloxy bromide (10.23 mmol) was used instead of 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyl bromide, 1.82 g of title compound (5) was obtained. (yield=56 %) 1 H -NMR (CDCl 3 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.20∼7.40 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.01 (s, 1H), 5.55 (m, 2H), 5.45 (s, 2H), 5.40 (s, 1H), 5.16∼5.25 (m, 1H), 4.10∼4.20 (m, 2H), 3.90 (s, 3H), 2.02∼2.22 (m, 12H) IR (KBr, cm -1 ) : 1750, 1620, 1435, 1360, 1240 Elemental analysis for C 31 H 32 O 14 Calculated (%) C 59.23 H 5.09 O 35.68 Found (%) C 59.42 H 5.15 O 35.43 EXAMPLE 6 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one (compound 6) In accordance with Example 2, 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one was used instead of 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one, 0.321 g the title compound (6) was obtained. (yield=81 %) 1 H -NMR (DMSO-d 6 , δ-TMS): 11.40 (bs, 1H), 7.67 (d, 1H, J=8.4Hz), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 6.00 (s, 1H), 5.55 (m, 2H), 5.40 (m, 1H), 4.23 (m, 2H), 4.15 (s, 1H), 3.75 (s, 3H), 2.02∼2.22 (m, 12H) IR (KBr, cm -1 ) : 3350, 1660, 1630, 1580, 1270 Elemental analysis for C 24 H 26 O 14 Calculated (%) C 53.53 H 4.83 O 41.64 Found (%) C 53.42 H 4.55 O 42.03 EXAMPLE 7 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 7) In accordance with Example 2, 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one was used instead of 3-methoxy-4-benzyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one, 0.309 g of the title compound (7) was obtained. (yield=78 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 11.40 (bs, 1H), 7.67 (d, 1H, J=8.4Hz), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 4.85 (d, 1H, J=7.6Hz), 3.85 (s, 3H), 3.65 (d, 1H, J=7.6Hz), 3.51 (d, 1H, J=7.6Hz), 3.41 (m, 1H), 3.20∼3.40 (m, 3H), 2.05∼2.22 (m, 12H) IR (KBr, cm -1 ) : 3350, 1660, 1630, 1580, 1270 Elemental analysis for C 24 H 26 O 14 Calculated (%) C 53.53 H 4.83 O 41.64 Found (%) C 53.42 H 4.55 O 42.03 EXAMPLE 8 3-methoxy-4-hydroxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one (compound 8) In accordance with Example 3, 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one was used instead of 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one, 0.310 g of the title compound (8) was obtained. (yield=78 %) 1 H-NMR (DMSO-d 6 , δ-TMS) : 11.40 (bs, 1H), 7.67 (d, 1H, J=8.4Hz), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 6.00 (s, 1H), 5.55 (m, 2H), 5.40 (m, 1H), 4.98 (bs, 4H), 4.23 (m, 2H), 4.15 (s, 1H), 3.75 (s, 3H) IR (KBr, cm -1 ) : 3350, 1660, 1630, 1580, 1270 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.52 H 4.85 O 43.63 EXAMPLE 9 3-methoxy-4-hydroxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 9) In accordance with Example 3, 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one was used instead of 3-methoxy-4-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one, 0.295 g of the title compound (9) was obtained. (yield=74 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 11.25 (bs, 1H), 7.67 (d, 1H, J=8.4Hz), 6.95 (s, 1H), 6.94 (d, 1H, J=8.4Hz), 5.00 (bs, 4H), 4.85 (d, 1H, J=7.6Hz), 3.85 (s, 3H), 3.65 (d, 1H, J=7.6Hz), 3.51 (d, 1H, J=7.6Hz), 3.41 (m, 1H), 3.20∼3.40 (m, 3H) IR (KBr, cm -1 ) : 3350, 1660, 1630, 1580, 1270 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.65 H 4.85 O 43.50 EXAMPLE 10 3-acetoxy-4-benzyloxy-7-(tetra-O-benzyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 10) In accordance with Example 1, 1.00 g of 3-acetoxy-4-benzyloxy-7-hydroxy-2H-1-benzopyran-2-one (3.06 mmol) and 2.70 g of 2, 3, 4, 6-tetra-O-benzyl-α-D-glucopyranosyl bromide (4.43 mmol) were used instead of 3-methoxy-4-benzyloxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyl bromide, 1.52 g of the title compound (10) was obtained. (yield=58 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 7.67 (d, 1H, J=8.8Hz), 7.15∼7.60 (m, 25H), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.25∼5.35 (m, 2H), 5.20 (m, 8H), 5.14 (t, 1H, J=8.0Hz), 4.93 (d, 1H, J=8.0Hz), 4.21∼4.28 (m, 2H), 3.82∼3.85 (m, 1H), 2.38 (s, 3H) IR (KBr, cm -1 ) : 1760, 1640, 1600, 1450, 1380 Elemental analysis for C 52 H 48 O 11 Calculated (%) C 73.58 H 5.66 O 20.76 Found (%) C 73.53 H 5.78 O 20.69 EXAMPLE 11 3-acetoxy-4-hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 11) Under argon atmosphere, 1.50 g of 3-acetoxy-4-benzyloxy-7-(tetra-O-benzyloxy-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (1.77 mmo) was dissolved in 150 ml of tetrahydrofuran at room temperature, and 0.15 g of 10 % palladium on activated carbon was added. After argon gas was replaced with hydrogen gas, the reaction mixture was stirred at room temperature for 2 hours. The catalyst was filtered off, and the filtrate was evaporated to give a crystalline product. 0.662 g of the title compound (11) was obtained after reprecipitation from tetrahydrofuran and hexane. (yield=94 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 10.5 (bs, 1H), 7.70 (d, 1H, J=8.4Hz), 6.70∼6.90 (m, 2H), 5.80 (bs, 1H), 5.32 (d, 1H, J=7.2Hz), 5.19 (s, 1H), 5.02 (s, 1H), 4.50 (s, 1H), 3.10∼3.70 (m, 6H), 2.33 (s, 3H) IR (KBr, cm -1 ) : 3400, 1780, 1670, 1610, 1580, 1270 Elemental analysis for C 17 H 18 O 11 Calculated (%) C 51.26 H 4.52 O 44.22 Found (%) C 51.27 H 4.51 O 44.22 EXAMPLE 12 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 12) 11.74 g of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one (40.18 mmol) and 24.74 g 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide (60.27 mmol) were dissolved in 360 ml of acetonitrile at room temperature under argon atmosphere. To this solution, 11.17 g of silver (l) oxide (48.21 mmol) and 106 g of molecular sieve 4A were added and the mixture was stirred at room temperature for 4 hours. After filtration, the filtrate was concentrated under reduced pressure, giving an oily residue. Purification of the residue on silica gel column chromatography ( eluent :hexane / ethyl acetate= 2/1) gave 13.00 g of the title compound (12). (yield=52 %) 1 H -NMR (DMSO-d 6 , δ-TMS) ; 7.77 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.20∼5.30 (m, 2H), 4.52 (t, 1H, J=6.6Hz), 4.46 (t, 2H, J=6.0Hz), 4.11 (d, 2H, J=6.0Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.96 (s, 3H), 1.70∼1.80 (m, 2H), 1.40∼1.55 (m, 2H), 0.93 (t, 3H, J=3.6Hz) IR (KBr, cm -1 ) : 2950, 1750, 1630, 1370, 1240 Elemental analysis for C 29 H 34 O 15 Calculated (%) C 55.95 H 5.50 O 38.55 Found (%) C 55.84 H 5.58 O 38.58 EXAMPLE 13 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 13) In accordance with Example 12, 12.86 g of 3-acetoxy-4-hexyloxy-7-hydroxy-2H-1-benzopyran-2-one (40.18 mmol) and 24.78 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyl bromide (60.27 mmol) were used instead of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide, 13.58 g of the title compound (13) was obtained. (yield=52 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.45 (t, 2H, J=6.0Hz), 4.10∼4.40 (m, 3H), 2.34 (s, 3H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 1.70∼1.80 (m, 2H), 1.25∼1.50 (m, 6H), 0.88 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 2950, 1750, 1620, 1370, 1240 Elemental analysis for C 31 H 38 O 15 Calculated (%) C 58.13 H 4.41 O 37.47 Found (%) C 58.20 H 4.45 O 37.35 EXAMPLE 14 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one (compound 14) In accordance with Example 12, 6.00 g of 3-acetoxy-4-hexyloxy-7-hydroxy-2H-1-benzopyran-2-one (18.73 mmol) and 11.55 g of 2, 3, 4, 6-tetra-O-acetyl-β-D-mannopyranosyloxy bromide (28.10 mmol) were used instead of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide, 3.66 g of the title compound (14) was obtained. (yield=30 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 7.78 (d, 1H, J=8.8Hz), 7.15∼7.30 (m, 2H), 5.94 (s, 1H), 5.35∼5.45 (m, 2H), 5.13 (t, 1H, J=10.0Hz), 4.45 (t, 2H, J=5.9Hz), 3.90∼4.20 (m, 3H), 2.34 (s, 3H), 2.18 (s, 3H), 2.05 (s, 3H), 2.00 (s, 3H), 1.92 (s, 3H), 1.70∼1.80 (m, 2H), 1.25∼1.50 (m, 6H), 0.88 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 1750, 1630, 1370, 1240 Elemental analysis for C 31 H 38 O 15 Calculated (%) C 58.13 H 4.41 O 37.47 Found (%) C 58.19 H 4.39 O 37.42 EXAMPLE 15 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 15) In accordance with Example 12, 4.50 g of 3-acetoxy-4-hexyloxy-7-hydroxy-2H-1-benzopyran-2-one (14.05 mmol) and 8.66 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide (21.07 mmol) were used instead of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide, 4.66 g of the title compound (15) was obtained. (yield=51 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=9.2Hz), 7.05∼7.15 (m, 2H), 5.66 (d, 1H, J=7.2Hz), 5.20∼5.40 (m, 2H), 4.50∼4.55 (m, 3H), 4.45 (t, 2H, J=6.2Hz), 4.12 (t, 2H, J=6.4Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.03 (s, 3H), 1.97 (s, 3H), 1.70∼1.80 (m, 2H), 1.25∼1.50 (m, 6H), 0.88 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 2930, 1750, 1620, 1370, 1230 Elemental analysis for C 31 H 38 O 15 Calculated (%) C 58.13 H 4.41 O 37.47 Found (%) C 58.16 H 4.45 O 37.39 EXAMPLE 16 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 16) In accordance with Example 12, 14.00 g of 3-acetoxy-4-octyloxy-7-hydroxy-2H-1-benzopyran-2-one (40.28 mmol) and 24.84 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-glucopyranosyloxy bromide (60.41 mmol) were used instead of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide, 13.65 g of the title compound (16) was obtained. (yield=50 %) 1 H -NMR (DMSO-d 6 , δ-TMS) ; 7.76 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.10∼5.15 (m, 1H), 5.04 (t, 1H, J=9.8Hz), 4.45 (t, 2H, J=6.0Hz), 4.05∼4.35 (m, 3H), 2.34 (s, 3H), 2.00∼2.05 (m, 9H), 1.99 (s, 3H), 1.70∼1.80 (m, 2H), 1.20∼1.50 (m,10H), 0.85 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2920, 1740, 1630, 1610, 1370, 1230 Elemental analysis for C 33 H 42 O 15 Calculated (%) C 58.40 H 6.24 O 35.36 Found (%) C 58.16 H 6.19 O 35.65 EXAMPLE 17 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 17) In accordance with Example 12, 14.00 g of 3-acetoxy-4-octyloxy-7-hydroxy-2H-1-benzopyran-2-one (40.28 mmol) and 24.84 g of 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide (60.41 mmol) were used instead of 3-acetoxy-4-butoxy-7-hydroxy-2H-1-benzopyran-2-one and 2, 3, 4, 6-tetra-O-acetyl-α-D-galactopyranosyloxy bromide, 14.47 g of the title compound (17) was obtained. (yield=53 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 7.76 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.04 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=7.2Hz), 5.20∼5.40 (m, 2H), 4.42 (t, 1H, J=6.4Hz), 4.45 (t, 2H, J=6.4Hz), 4.11 (d, 2H, J=6.0Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.03 (s, 3H), 1.97 (s, 3H), 1.70∼1.80 (m, 2H), 1.20∼1.50 (m, 10H), 0.85 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2930, 1750, 1620, 1370, 1230 Elemental analysis for C 33 H 42 O 15 Calculated (%) C 58.40 H 6.24 O 35.36 Found (%) C 58.51 H 6.29 O 35.20 EXAMPLE 18 3-hydroxy-4-butoxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 18) Under argon atmosphere, to a mixture of 19.07 g 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (30.63 mmol) in380 ml of methanol was added 3.31 g of sodium methoxide (61.26 mmol) at 5 ° and followed by stirring at room temperature for 1 hour. Then 27.85 g of Ambrtlyst-15 was added and the mixture was stirred at room temperature for 1 hour. Amberlyst-15 was filtered off and the filtrate was evaporated to give a crystalline product. 10.18 g of the title compound (18) was obtained after reprecipitation from ethanol. (yield=81 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.18 (s, 1H), 7.61 (d, 1H, J=8.8Hz), 7.00∼7.10 (m, 2H), 5.20 (d, 1H, J=5.6Hz), 4.91 (d, 1H, J=8.0Hz), 4.88 (d, 1H, J=5.2Hz), 4.67 (t, 1H, J=5.2Hz), 4.52 (d, 1H, J=4.4Hz), 4.48 (t, 2H, J=6.4Hz), 3.40∼3.75 (m, 6H), 1.65∼1.75 (m, 2H), 1.40∼1.50 (m, 2H), 0.93 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3400, 2950, 2930, 2860, 1680, 1640, 1610, 1250 Elemental analysis for C 19 H 24 O 10 Calculated (%) C 55.34 H 5.87 O 38.80 Found (%) C 55.41 H 5.81 O 38.78 EXAMPLE 19 3-hydroxy-4-hexyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 19) In accordance with Example 18, 10.94 g of 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (16.81 mmol) was used instead of 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one, 6.66 g of the title compound (19) was obtained. (yield=90 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.19 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.00∼7.10 (m, 2H), 5.37(bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.47 (t, 2H, J=6.2Hz), 3.10∼3.75 (m, 6H), 1.65∼1.80 (m, 2H), 1.20∼1.50 (m, 6H), 0.87 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) :3350, 2950, 2920, 2850, 1700, 1640, 1610, 1260 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.27 H 6.41 O 36.33 Found (%) C 55.25 H 6.49 O 38.46 EXAMPLE 20 3-hydroxy-4-hexyloxy-7-(α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one (compound 20) In accordance with Example 18, 13.40 g of 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-α-D-mannopyranosyloxy)-2H-1-benzopyran-2-one (20.60 mmol) was used instead of 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one, 7.62 g of the title compound (20) was obtained. (yield=84 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.47 (t, 2H, J=6.4Hz), 3.85 (s,1H), 3.20∼3.75 (m, 6H), 1.65∼1.80 (m, 2H), 1.20∼1.50 (m, 6H), 0.87 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) :3350, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.27 H 6.41 O 36.33 Found (%) C 57.38 H 6.40 O 36.22 EXAMPLE 21 3-hydroxy-4-hexyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 21) In accordance with Example 18, 12.57 g of 3-acetoxy-4-hexyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (19.32 mmol) was used instead of 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one, 7.55 g of the title compound (21) was obtained. (yield=89 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.00∼7.10 (m, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.47 (t, 2H, J=6.6Hz), 3.25∼3.65 (m, 6H), 1.70∼1.80 (m, 2H), 1.20∼1.50 (m, 6H), 0.87 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) :3400, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.27 H 6.41 O 36.33 Found (%) C 57.16 H 6.46 O 36.38 EXAMPLE 22 3-hydroxy-4-octyloxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (compound 22) In accordance with Example 18, 10.95 g of 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one (16.13 mmol) was used instead of 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one, 6.95 g of the title compound (22) was obtained. (yield=92 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.19 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.00∼7.10 (m, 2H), 5.37 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.59 (bs, 1H), 4.46 (t, 2H, J=6.4Hz), 3.10∼3.75 (m, 6H), 1.65∼1.80 (m, 2H), 1.15∼1.50 (m, 10H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.97 H 6.88 O 34.15 Found (%) C 58.92 H 6.87 O 34.21 EXAMPLE 23 3-hydroxy-4-octyloxy-7-(β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (compound 23) In accordance with Example 18, 20.67 g of 3-acetoxy-4-octyloxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one (30.46 mmol) was used instead of 3-acetoxy-4-butoxy-7-(tetra-O-acetyl-β-D-galactopyranosyloxy)-2H-1-benzopyran-2-one, 12.47 g of the title compound (23) was obtained. (yield=87 %) 1 H -NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.60 (d, 1H, J=8.4Hz), 7.00∼7.10 (m, 2H), 5.21 (bs, 1H), 4.91 (d, 1H, J=8.0Hz), 4.88 (bs, 1H), 4.66 (bs, 1H), 4.52 (d, 1H, J=3.6Hz), 4.47 (t, 2H, J=6.6Hz), 3.10∼3.75 (m, 6H), 1.65∼1.80 (m, 2H), 1.15∼1.50 (m, 10H), 0.85 (t, 3H, J=6.6Hz) IR (KBr, cm -1 ) : 3400, 2910, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.97 H 6.88 O 34.15 Found (%) C 58.99 H 6.92 O 34.09 (example 24∼160) The following Tables show 7-glycopyranosyloxy benzopyran derivatives (24)∼(160) obtained by the methods described in Examples. The abbreviations used in this table are as follows : Glc, glucopyranosyl group ; Man, mannopyranosyl group ; Gal, galactopyranosyl group ; R 4 , protecting group of sugar. Compound 24 1 H-NMR (DMSO-d 6, δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 25H), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.20 (m, 8H), 5.12 (t, 1H, J=8.0Hz), 4.95 (d, 1H,J=8.0Hz), 4.30∼4.20 (m, 2H), 3.85∼3.81 (m, 1H), 3.73 (s, 3H) IR (KBr, cm -1 ) : 1645, 1600, 1440, 1380 Elemental analysis for C 51 H 48 O 10 Calculated (%) C 74.62 H 5.89 O 19.49 Found (%) C 74.53 H 5.88 O 19.59 Compound 25 1 H-NMR (DMSO-d 6, δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.15 (m, 25H), 6.88 (d, 1H, J=8.8Hz), 6.82 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.22 (m, 8H), 5.17 (t, 1H, J=8.0Hz), 4.93 (d, 1H, J=8.0Hz), 4.40 (t, 2H, J=6.8Hz), 4.30∼4.21 (m, 2H), 3.85∼3.81 (m, 1H), 1.75∼1.24 (m, 4H), 0.93 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1645, 1610, 1435, 1380 Elemental analysis for C 54 H 54 O 10 Calculated (%) C 75.15; H 6.31; O 18.54 Found (%) C 75.23; H 6.28; O 18.49 Compound 26 1 H-NMR (DMSO-d 6, δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.10 (t, 1H, J=8.0Hz), 4.95 (d, 1H, J=8.0Hz), 4.52 (t, 2H, J=6.5Hz), 4.30∼4.20 (m, 2H), 3.85∼3.80 (m, 1H), 2.20∼2.00 (m, 12H), 1.78∼1.28 (m, 8H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1765, 1645, 1610, 1440, 1380 Elemental analysis for C 36 H 42 O 14 Calculated (%) C 61.89; H 6.06; O 32.05 Found (%) C 61.73; H 6.18; O 32.09 Compound 27 1 H-NMR (DMSO-d 6, δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.62∼7.20 (m, 5H), 6.90 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.10 (t, 1H, J=8.0Hz), 4.98 (d, 1H, J=8.0Hz), 4.50 (t, 2H, J=6.5Hz), 4.28∼4.20 (m, 2H), 3.84Å 3.80 (m, 1H), 2.20∼1.98 (m, 12H), 1.80∼1.25 (m, 12H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1765, 1645, 1600, 1445, 1380 Elemental analysis for C 38 H 46 O 14 Calculated (%) C 62.80; H 6.38; O 30.82 Found (%) ÅFC 62.83; H 6.43; O 30.74 Compound 28 1 H-NMR (DMSO-d 6, δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.79 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.08 (t, 1H, J=8.0Hz), 4.97 (d, 1H, J=8.0Hz), 4.52 (t, 2H, J=6.5Hz), 4.30∼4.18 (m, 2H), 3.85∼3.80 (m, 1H), 2.22∼2.00 (m, 12H), 1.80∼1.20 (m, 16H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1760, 1645, 1610, 1430, 1380 Elemental analysis for C 40 H 50 O 14 Calculated (%) C 63.65; H 6.68; O 29.67 Found (%) C 63.53; H 6.78; O 29.69 Compound 29 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.73 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 2H), 5.12 (t, 1H, J=8.0Hz), 4.95 (d, 1H, J=8.0Hz), 4.52 (t, 2H, J=6.5Hz), 4.27∼4.18 (m, 2H), 3.85∼3.80 (m, 1H), 2.20∼2.00 (m, 12H), 1.83∼1.25 (m, 20H), 0.90 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1765, 1640, 1605, 1440, 1380 Elemental analysis for C 42 H 54 O 14 Calculated (%) C 64.44; H 6.95; O 28.61 Found (%) C 64.53; H 6.78; O 28.69 Compound 30 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.74 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 5.42 (s, 2H), 5.35∼5.23 (m, 2H), 5.12 (t, 1H, J=8.0Hz), 4.97 (d, 1H, J=8.0Hz), 4.51 (m, 1H), 4.26∼4.16 (m, 2H), 3.83∼3.78 (m, 1H), 2.22∼2.00 (m, 12H), 1.03 (d, 6H, J=7.4Hz) IR (KBr, cm -1 ) : 1770, 1650, 1605, 1435, 1380 Elemental analysis for C 33 H 36 O 14 Calculated (%) C 60.36; H 5.53; O 34.11 Found (%) C 60.33; H 5.68; O 33.99 Compound 31 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.18 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.44 (s, 2H), 5.32∼5.24 (m, 2H), 5.12 (t, 1H, J=8.0Hz), 5.00 (m, 1H), 4.95 (d, 1H, J=8.0Hz), 4.28∼4.18 (m, 2H), 3.84∼3.80 (m, 1H), 2.23∼1.26 (m, 21H), 0.96 (d, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 1760, 1640, 1605, 1445, 1380 Elemental analysis for C 37 H 42 O 14 Calculated (%) C 62.53; H 5.96; O 31.51 Found (%) C 62.83; H 5.75; O 31.42 Compound 32 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.87 (d, 1H, J=8.8Hz), 6.75 (s, 1H), 6.44 (dd, 1H, J=17.5Hz, J=9.4Hz), 5.42 (s, 2H), 5.34∼5.24 (m, 2H), 5.12 (t, 1H, J=8.0Hz), 4.95 (d, 1H, J=8.0Hz), 4.28∼4.16 (m, 2H), 4.13 (dd, 1H,J=17.6Hz, J=2.0Hz), 3.91 (dd, 1H, J=9.4Hz, J=1.9Hz), 3.85∼3.79(m, 1H), 2.19∼2.00 (m, 12H) IR (KBr, cm -1 ) : 1765, 1635, 1600, 1440, 1375 Elemental analysis for C 32 H 32 O 14 Calculated (%) C 60.00; H 5.04; O 34.96 Found (%) C 59.93; H 5.08; O 34.99 Compound 33 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.58∼7.20 (m, 5H), 6.86 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 5.42 (s, 2H), 5.35∼5.25 (m, 4H), 5.10 (t, 1H, J=8.0Hz), 4.97 (d, 1H, J=8.0Hz), 4.28∼4.22 (m, 4H), 3.86∼3.81 (m, 1H), 2.30∼1.94 (m, 16H),0.98 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 1765, 1650, 1610, 1440, 1370 Elemental analysis for C 36 H 40 O 14 Calculated (%) C 62.06; H 5.79; O 32.15 Found (%) C 62.13; H 5.78; O 32.09 Compound 34 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.74 (d, 1H, J=8.8Hz), 7.62∼7.22 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.76 (s, 1H), 5.42 (s, 2H), 5.36∼5.26 (m, 3H), 5.10 (m, 2H), 4.95 (d, 1H, J=8.0Hz), 4.27∼4.17(m, 2H), 4.12 (d, 2H, J=8.6Hz), 3.86∼3.80 (m, 1H), 2.19∼1.98(m, 16H), 1.68 (s, 6H), 1.59 (s, 3H) IR (KBr, cm -1 ) : 1760, 1645, 1605, 1440, 1370 Elemental analysis for C 40 H 46 O 14 Calculated (%) C 63.99; H 6.18; O 29.83 Found (%) C 63.83; H 6.24; O 29.93 Compound 35 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.67 (d, 1H, J=8.8Hz), 7.55∼7.15 (m, 25H), 6.73 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 5.38 (s, 2H), 5.37∼5.24 (m, 2H), 5.15 (m, 8H), 5.10 (t, 1H, J=8.0Hz), 4.96 (d, 1H, J=8.0Hz), 4.51 (t, 2H, J=6.8Hz), 4.24∼4.19 (m, 2H), 3.86∼3.82 (m, 1H), 1.77∼1.20 (m, 12H), 0.91 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1645, 1610, 1440, 1380 Elemental analysis for C 58 H 62 O 10 Calculated (%) C 75.79; H 6.80; O 17.41 Found (%) C 75.83; H 6.78; O 17.39 Compound 36 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.70∼7.15 (m, 30H), 6.90 (d, 1H, J=8.8Hz), 6.79 (s, 1H), 5.45 (s, 2H), 5.35∼5.25 (m, 2H), 5.17 (m, 10H), 5.08 (t, 1H, J=8.0Hz), 4.90 (d, 1H, J=8.0Hz), 4.29∼4.21 (m, 2H), 3.87∼3.78 (m, 1H) IR (KBr, cm -1 ) : 1640, 1605, 1445, 1370 Elemental analysis for C 57 H 52 O 10 Calculated (%) C 76.32; H 5.84; O 17.84 Found (%) C 76.53; H 5.78; O 17.69 Compound 37 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.32 (bs, 1H), 7.59 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.39 (bs, 1H), 5.11 (bs, 1H), 5.06 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.60 (bs, 1H), 4.25 (t, 2H, J=6.2Hz), 3.76∼3.10 (m, 6H), 1.80∼1.20 (m, 4H), 0.88 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3350, 2960, 2920, 2840, 1700, 1645, 1610, 1260 Elemental analysis for C 19 H 24 O 10 Calculated (%) C 55.33; H 5.87; O 38.80 Found (%) C 55.29; H 5.89; O 38.82 Compound 38 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.45 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.11∼7.02 (m, 2H), 5.35 (bs, 1H), 5.09 (bs, 1H), 5.04 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.57 (bs, 1H), 4.42 (t, 2H, J=6.4Hz), 3.82∼3.12 (m, 6H), 1.80∼1.20 (m, 8H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) ; 3345, 2920, 2850, 1710, 1635, 1610, 1250 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.26; H 6.41; O 36.33 Found (%) C 57.20; H 6.35; O 36.45 Compound 39 1 H-NMR (DMSO-d 6 , δ-TMS): 10.40 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.12∼7.02 (m, 2H), 5.37 (bs, 1H), 5.10 (bs, 1H), 5.04 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.56 (bs, 1H), 4.41 (t, 2H, J=6.4Hz), 3.80∼3.12 (m, 6H), 1.82∼1.13 (m, 12H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2920, 2845, 1700, 1635, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.96; H 6.89; O 34.15 Found (%) C 59.06; H 6.77; O 34.17 Compound 40 1 H-NMR (DMSO-d 6 , δ-TMS): 10.20 (bs, 1H), 7.62 (d, 1H, J=8.8Hz), 7.12∼7.02 (m, 2H), 5.33 (bs, 1H), 5.12 (bs, 1H), 5.04 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.56 (bs, 1H), 4.38 (t, 2H, J=6.4Hz), 3.75∼3.10 (m, 6H), 1.85∼1.15 (m, 16H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3340, 2925, 2845, 1705, 1650, 1620, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 60.47; H 7.31; O 32.22 Found (%) C 60.45; H 7.35; O 32.20 Compound 41 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.45 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.39 (bs, 1H), 5.13 (bs, 1H), 5.05 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.57 (bs, 1H), 4.25 (t, 2H, J=6.4Hz), 3.80∼3.18 (m, 6H), 1.80∼1.60 (m, 2H), 1.52∼1.12 (m, 18H), 0.88 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2910, 2850, 1700, 1650, 1610, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81; H 7.69; O 30.50 Found (%) C 61.77; H 7.55; O 30.68 Compound 42 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.43 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.35 (bs, 1H), 5.10 (bs, 1H), 5.05 (bs, 1H), 4.99 (d, 1H, J=6.8Hz), 4.62 (bs, 1H), 4.45 (m, 1H), 3.75∼3.10 (m, 6H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3330, 3300, 2940, 2850, 1700, 1600, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27; H 5.57; O 40.16 Found (%) C 54.28; H 5.69; O 40.03 Compound 43 1 H-NMR (CDCl 3 , δ-TMS) : 10.38 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.01 (m, 2H), 5.35 (bs, 1H), 5.10 (bs, 1H), 5.03 (bs, 1H), 4.98 (m, 1H), 4.93 (d, 1H, J=6.8Hz), 4.53 (bs, 1H), 3.80∼3.09 (m, 6H), 2.00∼1.22 (m, 9H), 0.95 (d, 3H, J=6.5Hz) IR (KBr, cm -1 ) : 3335, 3300, 2955, 2850, 1710, 1620, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40; H 6.24; O 35.36 Found (%) C 58.35; H 6.29; O 35.36 Compound 44 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.48 (bs, 1H), 7.65 (d, 1H, J=8.8Hz), 7.13∼7.03 (m, 2H), 6.57 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.35 (bs, 1H), 5.15 (bs, 1H), 5.08 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.17 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.95 (dd, 1H, J=9.5Hz, J=2.0Hz), 3.80∼3.12 (m, 6H) IR (KBr, cm -1 ) : 3340, 3310, 2950, 2845, 1700, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40; H 4.75; O 41.85 Found (%) C 53.57; H 4.69; O 41.74 Compound 45 1 H-NMR (DMSO-d 6 , δ-TMS): 10.40 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.50 (m, 1H), 5.34 (m, 2H), 5.11 (bs, 1H), 5.03 (bs, 1H), 4.98 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.83∼3.15 (m, 6H), 2.25∼1.96 (m, 4H), 0.99 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 1710, 1640, 1615, 1260 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53; H 5.98; O 36.49 Found (%) C 57.65; H 5.89; O 36.46 Compound 46 1 H-NMR (DMSO-d 6 , δ-TMS): 10.35 (bs, 1H), 7.61 (d, 1H, J=8.8Hz),7.12∼7.00 (m, 2H), 5.38 (m, 1H), 5.34 (bs, 1H), 5.10 (m, 2H), 5.05 (bs, 1H), 4.98 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.10 (d,2H, J=8.5Hz), 3.80∼3.15 (m, 6H), 2.05 (m, 4H), 1.67 (s, 6H),1.60 (s, 3H) IR (KBr, cm -1 ) : 3345, 2950, 2920, 1705, 1640, 1610, 1260 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96; H 6.55; O 32.49 Found (%) C 60.85; H 6.70; O 32.45 Compound 47 1 H-NMR (DMSO-d 6 , δ-TMS): 10.50 (bs, 1H), 7.61 (d, 1H, J=8.8Hz),7.30∼7.15 (m, 5H), 7.10∼7.00 (m, 2H), 5.35 (bs, 1H), 5.25 (s,2H), 5.11 (bs, 1H), 5.00 (bs, 1H), 4.93 (d, 1H, J=6.8Hz), 4.55(bs, 1H), 3.80∼3.10 (m, 6H) IR (KBr, cm -1 ) : 3340, 3300, 2955, 2850, 1710, 1620, 1260 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19; H 4.97; O 35.84 Found (%) C 59.15; H 4.89; O 35.96 Compound 48 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.60∼7.20 (m,25H), 6.88 (d, 1H, J=8.8Hz), 6.75 (s, 1H), 6.00 (S, 1H), 5.54(m, 2H), 5.43 (s, 2H), 5.39 (m, 1H), 5.20 (m, 8H),4.24 (m, 2H),4.15 (s, 1H), 3.73 (s, 3H) IR (KBr, cm -1 ) : 1645, 1610, 1440, 1380 Elemental analysis for C 51 H 48 O 10 Calculated (%) C 74.62; H 5.89; O 19.49 Found (%) C 74.56; H 5.84; O 19.60 Compound 49 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.15 (m,25H), 6.88 (d, 1H, J=8.8Hz), 6.75 (s, 1H), 6.00 (S, 1H), 5.55(s, 2H), 5.42 (s, 2H), 5.40 (m, 1H), 5.22 (m, 8H), 4.42 (t, 2H, J=6.7Hz), 4.25 (m, 2H), 4.15 (s, 1H), 1.75∼1.24 (m, 4H), 0.93 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1645, 1610, 1435, 1380 Elemental analysis for C 54 H 54 O 10 Calculated (%) C 75.15; H 6.31; O 18.54 Found (%) C 75.23; H 6.28; O 18.49 Compound 50 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.20 (m,5H), 6.88 (d, 1H, J=8.8Hz), 6.79 (s, 1H), 6.02 (s, 1H), 5.56 (m,2H), 5.42 (s, 2H), 5.40 (m, 1H), 4.50 (t, 2H,J=6.5Hz), 4.24 (m, 2H), 4.15 (s, 1H), 2.18∼1.98 (m, 12H), 1.80∼1.30 (m, 8H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1765, 1645, 1610, 1435, 1380 Elemental analysis for C 36 H 42 O 14 Calculated (%) C 61.89; H 6.06; O 32.05 Found (%) C 61.74; H 6.10; O 32.06 Compound 51 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.62∼7.20 (m, 5H), 6.90 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.02 (s, 1H), 5.56 (m, 2H), 5.44 (s, 2H), 5.41 (m, 1H), 4.50 (t, 2H, J=6.5Hz), 4.25 (m, 2H), 4.13 (s, 1H), 2.20∼1.98 (m, 12H), 1.80∼1.25 (m, 12H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ): 1760, 1640, 1600, 1445, 1380 Elemental analysis for C 38 H 46 O 14 Calculated (%) C 62.80; H 6.38; O 30.82 Found (%) C 62.87; H 6.33; O 30.80 Compound 52 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.03 (s, 1H), 5.57 (m, 2H), 5.42 (s, 2H), 5.40 (m, 1H), 4.52 (t, 2H, J=6.5Hz), 4.25 (m, 2H), 4.13 (s, 1H), 2.23∼2.00 (m, 12H), 1.81∼1.21 (m, 16H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1760, 1635, 1600, 1430, 1380 Elemental analysis for C 40 H 50 O 14 Calculated (%) C 63.65; H 6.68; O 29.67 Found (%) C 63.63; H 6.85; O 29.52 Compound 53 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.02 (s, 1H), 5.60 (m, 2H), 5.43 (s, 2H), 5.38 (m, 1H), 4.51 (t, 2H, J=6.5Hz), 4.23 (m, 2H), 4.12 (s, 1H), 2.20∼2.02 (m, 12H), 1.84∼1.24 (m, 20H),0.90 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1760, 1640, 1610, 1440, 1380 Elemental analysis for C 42 H 54 O 14 Calculated (%) C 64.44; H 6.95; O 28.61 Found (%) C 64.47; H 6.88; O 28.65 Compound 54 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.56∼7.17 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.00 (s, 1H), 5.59 (m, 2H), 5.42 (s, 2H), 5.39 (m, 1H), 4.50 (m, 1H), 4.23 (m, 2H), 4.12 (s, 1H), 2.22∼2.00 (m, 12H), 1.05 (d, 6H, J=7.4Hz) IR (KBr, cm -1 ) : 1770, 1645, 1605, 1430, 1380 Elemental analysis for C 33 H 36 O 14 Calculated (%) C 60.36; H 5.53; O 34.11 Found (%) C 60.39; H 5.64; O 33.97 Compound 55 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.02 (s, 1H), 5.60 (m, 2H), 5.44 (s, 2H), 5.41 (m, 1H), 5.00 (m, 1H), 4.22 (m, 2H), 4.13 (s, 1H), 2.23∼1.26 (m, 21H), 0.96 (d, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 1750, 1640, 1600, 1445, 1380 Elemental analysis for C 37 H 42 O 14 Calculated (%) C 62.53; H 5.96; O 31.51 Found (%) C 62.63; H 5.85; O 31.52 Compound 56 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.73 (d, 1H, J=8.8Hz), 7.59∼7.18 (m, 5H), 6.87 (d, 1H, J=8.8Hz), 6.74 (s, 1H), 6.44 (dd, 1H, J=17.5Hz, J=9.4Hz), 6.00 (s, 1H), 5.50 (m, 2H), 5.42 (s, 2H), 5.40 (m, 1H), 4.24 (m, 2H), 4.15 (s, 1H), 4.13 (dd, 1H, J=17.6Hz, J=2.0 Hz), 3.91 (dd, 1H, J=9.4Hz, J=1.9Hz), 2.22∼2.00 (m, 12H) IR (KBr, cm -1 ) : 1765, 1640, 1600, 1435, 1375 Elemental analysis for C 32 H 32 O 14 Calculated (%) C 60.00; H 5.04; O 34.96 Found (%) C 59.97; H 5.10; O 34.93 Compound 57 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.58∼7.20 (m,5H), 6.86 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.00 (s, 1H), 5.50 (m, 2H), 5.43 (s, 2H), 5.41 (m, 1H), 5.34 (m, 2H), 4.26 (t, 2H, J=6.2Hz), 4.23 (m, 2H), 4.14 (s, 1H), 2.30∼1.96 (m, 16H), 0.98 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ): 1760, 1650, 1610, 1440, 1370 Elemental analysis for C 36 H 40 O 14 Calculated (%) C 62.06; H 5.79; O 32.15 Found (%) C 62.03; H 5.88; O 32.09 Compound 58 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.76 (s, 1H), 6.02 (s, 1H), 5.50 (m, 2H), 5.44 (s, 2H), 5.41 (m, 1H), 5.35 (m, 1H), 5.13 (m, 1H), 4.23 (m, 2H), 4.14 (s, 1H), 4.12 (d, 2H, J=8.6Hz), 2.20∼1.98 (m, 16H), 1.68 (s, 6H), 1.58 (s, 3H) IR (KBr, cm -1 ) : 1765, 1645, 1600, 1440, 1370 Elemental analysis for C 40 H 46 O 14 Calculated (%) C 63.99; H 6.18; O 29.83 Found (%) C 63.88; H 6.23; O 29.89 Compound 59 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.69 (d, 1H, J=8.8Hz), 7.55∼7.15 (m, 25H), 6.73 (d, 1H, J=8.8Hz), 6.81 (s, 1H), 6.01 (s, 1H), 5.49 (m, 2H), 5.40 (m, 1H), 5.36 (s, 2H), 5.15 (m, 8H), 4.49 (t, 2H, J=6.8Hz), 4.23 (m, 2H), 4.14 (s, 1H), 1.80∼1.20 (m, 12H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1650, 1610, 1435, 1380 Elemental analysis for C 58 H 62 O 10 Calculated (%) C 75.79; H 6.80; O 17.41 Found (%) C 75.87; H 6.74; O 17.39 Compound 60 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.15 (m, 30H), 6.90 (d, 1H, J=8.8Hz), 6.80 (s, 1H) 6.01 (s, 1H), 5.49 (m, 2H), 5.46 (s, 2H), 5.41 (m, 1H), 5.17 (m, 10H), 4.22 (m, 2H), 4.15 (s, 1H) IR (KBr, cm -1 ) : 1640, 1600, 1445, 1370 Elemental analysis for C 57 H 52 O 10 Calculated (%) C 76.32; H 5.84; O 17.84 Found (%) C 76.56; H 5.79; O 17.65 Compound 61 1 H-NMR (DMSO-d 6 , δ-TMS): 10.13 (s, 1H), 9.20 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.15 (d, 1H, J=2.4Hz), 7.10 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.09 (bs, 1H), 4.85 (bs, 1H), 4.80 (bs, 1H), 3.85 (s, 1H), 3.75∼3.25 (m, 6H) IR (KBr, cm -1 ) : 3340, 2950, 2910, 2850, 1690, 1620, 1610, 1250 Elemental analysis for C 15 H 16 O 10 Calculated (%) C 50.56; H 4.53; O 44.91 Found (%) C 50.42; H 4.58; O 45.00 Compound 62 1 H-NMR (DMSO-d 6 , δ-TMS): 10.35 (bs, 1H), 7.57 (d, 1H, J=8.8Hz), 7.14 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.08 (bs, 1H), 4.90 (bs, 1H), 4.77 (bs, 1H), 4.45 (t, 2H, J=6.4Hz), 3.87 (s, 1H), 3.78∼3.20 (m, 6H), 1.75∼1.20 (m, 4H), 0.86 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3345, 2950, 2900, 2850, 1690, 1635, 1600, 1250 Elemental analysis for C 19 H 24 O 10 Calculated (%) C 55.33; H 5.87; O 38.80 Found (%) C 55.35; H 5.90; O 38.75 Compound 63 1 H-NMR (DMSO-d 6 , δ-TMS): 10.15 (bs, 1H), 7.56 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.09 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.05 (bs, 1H), 4.90 (bs, 1H), 4.77 (bs, 1H), 4.45 (t, 2H, J=6.4Hz), 3.86 (s, 1H), 3.75∼3.20 (m, 6H), 1.70∼1.30 (m, 8H), 0.90 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3355, 2950, 2900, 2850, 1670, 1630, 1610, 1250 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.26; H 6.41; O 36.33 Found (%) C 57.35; H 6.35; O 36.30 Compound 64 1 H-NMR (DMSO-d 6 , δ-TMS): 10.25 (bs, 1H), 7.58 (d, 1H, J=8.8Hz), 7.14 (d, 1H, J=2.4Hz), 7.09 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.08 (bs, 1H), 4.89 (bs, 1H), 4.77 (bs, 1H), 4.45 (t, 2H, J=6.4Hz), 3.87 (s, 1H), 3.76∼3.23 (m, 6H), 1.80∼1.30 (m, 12H), 0.87 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2910, 2850, 1680, 1635, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.96; H 6.89; O 34.15 Found (%) C 58.85; H 6.85; O 34.30 Compound 65 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.05 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.15 (d, 1H, J=2.4Hz), 7.09 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.45 (s, 1H), 5.09 (bs, 1H), 4.85 (bs, 1H), 4.74 (bs, 1H), 4.42 (t, 2H, J=6.4Hz), 3.85 (s, 1H), 3.80∼3.25 (m, 6H), 1.75∼1.20 (m, 16H), 0.88 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2940, 2920, 2850, 1680, 1630, 1610, 1245 Elemental analysis for C 25 H 36 O 10 Calculated (%) C 60.47; H 7.31; O 32.22 Found (%) C 60.45; H 7.40; O 32.15 Compound 66 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.85 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.08 (bs, 1H), 4.90 (bs, 1H), 4.80 (bs, 1H), 4.42 (t, 2H, J=6.4Hz), 3.88 (s, 1H), 3.70∼3.15 (m, 6H), 1.95∼1.20 (m, 20H), 0.85 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2915, 2850, 1685, 1630, 1600, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81; H 7.69; O 30.50 Found (%) C 61.75; H 7.55; O 30.70 Compound 67 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.98 (bs, 1H), 7.63 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.08 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.87 (bs, 1H), 4.76 (bs, 1H), 4.43 (m, 1H), 3.88 (s, 1H), 3.78∼3.12 (m, 6H), 1.07 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3330, 2950, 2910, 2845, 1690, 1630, 1615, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27; H 5.57; O 40.16 Found (%) C 54.18; H 5.65; O 40.17 Compound 68 1 H-NMR (CDCl 3 , δ-TMS) : 10.00 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.89 (bs, 1H), 4.76 (bs, 1H), 3.75∼3.25 (m, 6H), 2.25∼1.20 (m, 9H), 0.97 (d, 3H, J=6.7Hz) IR (KBr, cm -1 ) : 3335, 2940, 2920, 2855, 1690, 1625, 1610, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40; H 6.24; O 35.36 Found (%) C 58.33; H 6.34; O 35.33 Compound 69 1 H-NMR (DMSO-d 6 , δ-TMS): 10.10 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.13 (d, 1H, J=2.4Hz), 7.08 (dd, 1H, J=2.2Hz, J=9.0Hz), 6.45 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.50 (s, 1H), 5.10 (bs, 1H), 4.87 (bs, 1H), 4.77 (bs, 1H), 4.13 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.95 (dd, 1H, J=9.5Hz, J=2.0Hz), 3.87 (s, 1H), 3.76∼3.21 (m, 6H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2840, 1695, 1630, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40; H 4.75; O 41.85 Found (%) C 53.43; H 4.80; O 41.77 Compound 70 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.78 (bs, 1H), 7.58 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.54 (m, 1H), 5.35 (m.2H), 5.08 (bs, 1H), 4.85 (bs, 1H), 4.78 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.88 (s, 1H), 3.70∼3.25 (m, 6H), 2.25∼1.90 (m, 4H), 0.99 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3340, 2950, 2910, 2850, 1685, 1630, 1615, 1250 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53; H 5.98; O 36.49 Found (%) C 57.60; H 5.83; O 36.57 Compound 71 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.95 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.41 (m, 1H), 5.16 (m, 1H), 5.09 (bs, 1H), 4.87 (bs, 1H), 4.77 (bs, 1H), 4.10 (d, 2H J=8.5Hz), 3.85 (s, 1H), 3.75∼3.25 (m, 6H), 2.00 (m, 4H), 1.64 (s, 6H), 1.58 (s, 3H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2845, 1690, 1620, 1600, 1250 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96; H 6.55; O 32.49 Found (%) C 60.89; H 6.60; O 32.51 Compound 72 1 H-NMR (DMSO-d 6 , δ-TMS): 10.30 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.38 (m, 5H), 7.15 (d, 1H, J=2.4Hz), 7.09 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.25 (s, 2H), 5.07 (bs, 1H), 4.90 (bs, 1H), 4.79 (bs, 1H), 3.85 (s, 1H), 3.76∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3335, 2960, 2930, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19; H 4.97; O 35.84 Found (%) C 59.25; H 4.89; O 35.86 Compound 73 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 25H), 6.88 (d, 1H, J=8.8Hz), 6.75 (s, 1H), 6.00 (S, 1H), 5.54 (m, 2H), 5.43 (s, 2H), 5.39 (s, 1H), 5.25∼5.15 (m, 9H), 4.20∼4.11 (m, 2H), 3.73 (s, 3H) IR (KBr, cm -1 ) : 1645, 1610, 1440, 1380 Elemental analysis for C 51 H 48 O 10 Calculated (%) C 74.62; H 5.89; O 19.49 Found (%) C 74.56; H 5.84; O 19.60 Compound 74 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.15 (m, 25H), 6.88 (d, 1H, J=8.8Hz), 6.75 (s, 1H), 6.00 (S, 1H), 5.55 (s, 2H), 5.42 (s, 2H), 5.40 (s, 1H), 5.26∼5.16 (m, 9H), 4.42 (t, 2H, J=6.7Hz), 4.22∼4.09 (m, 2H), 1.75∼1.24 (m, 4H), 0.93 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1645, 1610, 1435, 1380 Elemental analysis for C 54 H 54 O 10 Calculated (%) C 75.15; H 6.31; O 18.54 Found (%) C 75.23; H 6.28; O 18.49 Compound 75 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.79 (s, 1H), 6.02 (s, 1H), 5.56 (m, 2H), 5.42 (s, 2H), 5.40 (s, 1H), 5.24∼5.16 (m, 1H), 4.50 (t, 2H, J=6.5Hz), 4.20∼4.08 (m, 2H), 2.18∼1.98 (m, 12H), 1.80∼1.30 (m, 8H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1765, 1645, 1610, 1435, 1380 Elemental analysis for C 36 H 42 O 14 Calculated (%) C 61.89; H 6.06; O 32.05 Found (%) C 61.74; H 6.10; O 32.06 Compound 76 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.62∼7.20 (m, 5H), 6.90 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.02 (s, 1H), 5.56 (m, 2H), 5.44 (s, 2H), 5.41 (s, 1H), 5.22∼5.14 (m, 1H), 4.50 (t, 2H, J=6.5Hz), 4.20∼4.10 (m, 2H), 2.20∼1.98 (m, 12H), 1.80∼1.25 (m, 12H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1760, 1640, 1600, 1445, 1380 Elemental analysis for C 38 H 46 O 14 Calculated (%) C 62.80; H 6.38; O 30.82 Found (%) C 62.87; H 6.33; O 30.80 Compound 77 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.88 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.03 (s, 1H), 5.57 (m, 2H), 5.42 (s, 2H), 5.40 (s, 1H), 5.23∼5.15 (m, 1H), 4.52 (t, 2H, J=6.5Hz), 4.21∼4.08 (m, 2H), 2.23∼2.00 (m, 12H), 1.81∼1.21 (m, 16H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ): 1760, 1635, 1600, 1430, 1380 Elemental analysis for C 40 H 50 O 14 Calculated (%) C 63.65; H 6.68; O 29.67 Found (%) C 63.63; H 6.85; O 29.52 Compound 78 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.02 (s, 1H), 5.60 (m, 2H), 5.43 (s, 2H), 5.38 (s, 1H), 5.22∼5.13 (m, 1H), 4.51 (t, 2H, J=6.5Hz), 4.20∼4.09 (m, 2H), 2.20∼2.02 (m, 12H), 1.84∼1.24 (m, 20H), 0.90 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1760, 1640, 1610, 1440, 1380 Elemental analysis for C 42 H 54 O 14 Calculated (%) C 64.44; H 6.95; O 28.61 Found (%) C 64.47; H 6.88; O 28.65 Compound 79 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.71 (d, 1H, J=8.8Hz), 7.56∼7.17 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.00 (s, 1H), 5.59 (m, 2H), 5.42 (s, 2H), 5.39 (s, 1H), 5.24∼5.16 (m, 1H), 4.50 (m, 1H), 4.19∼4.08 (m, 2H), 2.22∼2.00 (m, 12H), 1.05 (d, 6H, J=7.4Hz) IR (KBr, cm -1 ) : 1770, 1645, 1605, 1430, 1380 Elemental analysis for C 33 H 36 O 14 Calculated (%) C 60.36; H 5.53; O 34.11 Found (%) C 60.39; H 5.64; O 33.97 Compound 80 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.02 (s, 1H), 5.60 (m, 2H), 5.44 (s, 2H), 5.41 (s, 1H), 5.23∼5.14 (m, 1H), 5.00 (m, 1H), 4.21∼4.09 (m, 2H), 2.23∼1.26 (m, 21H), 0.96 (d, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 1750, 1640, 1600, 1445, 1380 Elemental analysis for C 37 H 42 O 14 Calculated (%) C 62.53; H 5.96; O 31.51 Found (%) C 62.63; H 5.85; O 31.52 Compound 81 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.73 (d, 1H, J=8.8Hz), 7.59∼7.18 (m, 5H), 6.87 (d, 1H, J=8.8Hz), 6.74 (s, 1H), 6.44 (dd, 1H, J=17.5Hz, J=9.4Hz), 6.00 (s, 1H), 5.50 (m, 2H), 5.42 (s, 2H), 5.40 (s, 1H), 5.23∼5.15 (m, 1H), 4.20∼4.10 (m, 2H), 4.13 (dd, 1H, J=17.6Hz, J=2.0Hz), 3.91 (dd, 1H, J=9.4Hz, J=1.9Hz), 2.22∼2.00 (m, 12H) IR (KBr, cm -1 ) : 1765, 1640, 1600, 1435, 1375 Elemental analysis for C 32 H 32 O 14 Calculated (%) C 60.00; H 5.04; O 34.96 Found (%) C 59.97; H 5.10; O 34.93 Compound 82 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.70 (d, 1H, J=8.8Hz), 7.58∼7.20 (m, 5H), 6.86 (d, 1H, J=8.8Hz), 6.78 (s, 1H), 6.00 (s, 1H), 5.50 (m, 2H), 5.43 (s, 2H), 5.41 (s, 1H), 5.34 (m, 2H), 5.21∼5.13 (m, 1H), 4.26 (t, 2H, J=6.2Hz), 4.20∼4.12 (m, 2H), 2.30∼1.96 (m, 16H), 0.98 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 1760, 1650, 1610, 1440, 1370 Elemental analysis for C 36 H 40 O 14 Calculated (%) C 62.06; H 5.79; O 32.15 Found (%) C 62.03; H 5.88; O 32.09 Compound 83 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.72 (d, 1H, J=8.8Hz), 7.60∼7.20 (m, 5H), 6.85 (d, 1H, J=8.8Hz), 6.76 (s, 1H), 6.02 (s, 1H), 5.50 (m, 2H), 5.44 (s, 2H), 5.41 (s, 1H), 5.34 (m, 1H), 5.20∼5.13 (m, 2H), 4.19∼4.11 (m, 2H), 4.12 (d, 2H, J=8.6Hz), 2.20∼1.98 (m, 16H), 1.68 (s, 6H), 1.58 (s, 3H) IR (KBr, cm -1 ) : 1765, 1645, 1600, 1440, 1370 Elemental analysis for C 40 H 46 O 14 Calculated (%) C 63.99; H 6.18; O 29.83 Found (%) C 63.88; H 6.23; O 29.89 Compound 84 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.69 (d, 1H, J=8.8Hz), 7.55∼7.15 (m, 25H), 6.73 (d, 1H, J=8.8Hz), 6.81 (s, 1H), 6.01 (s, 1H), 5.49 (m, 2H), 5.40 (s, 1H), 5.36 (s, 2H), 5.22∼5.14 (m, 9H), 4.49 (t, 2H, J=6.8Hz), 4.18∼4.10 (m, 2H), 1.80∼1.20 (m, 12H), 0.89 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 1650, 1610, 1435, 1380 Elemental analysis for C 58 H 62 O 10 Calculated (%) C 75.79; H 6.80; O 17.41 Found (%) C 75.87; H 6.74; O 17.39 Compound 85 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.68 (d, 1H, J=8.8Hz), 7.60∼7.15 (m, 30H), 6.90 (d, 1H, J=8.8Hz), 6.80 (s, 1H), 6.01 (s, 1H), 5.49 (m, 2H), 5.46 (s, 2H), 5.41 (s, 1H), 5.22∼5.15 (m, 11H), 4.18∼4.09 (m, 2H) IR (KBr, cm -1 ) : 1640, 1600, 1445, 1370 Elemental analysis for C 57 H 52 O 10 Calculated (%) C 76.32; H 5.84; O 17.84 Found (%) C 76.56; H 5.79; O 17.65 Compound 86 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.25 (bs, 1H), 7.60 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.22 (bs, 1H), 4.96 (d, 1H, J=7.6Hz), 4.90 (bs, 1H), 4.68 (bs, 1H), 4.55 (bs, 1H), 4.50 (t, 2H, J=6.6Hz), 3.64∼3.24 (m, 6H), 1.75∼1.20 (m, 4H), 0.88 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3400, 2940, 2900, 2840, 1670, 1635, 1610, 1250 Elemental analysis for C 19 H 24 O 10 Calculated (%) C 55.33; H 5.87; O 38.80 Found (%) C 55.30; H 5.93; O 38.77 Compound 87 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.35 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.08∼6.98 (m, 2H), 5.20 (bs, 1H), 4.97 (d, 1H, J=7.6Hz), 4.90 (bs, 1H), 4.68 (bs, 1H), 4.54 (bs, 1H), 4.49 (t, 2H, J=6.6Hz), 3.65∼3.24 (m, 6H), 1.81∼1.20 (m, 8H), 0.90 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3400, 2960, 2900, 2840, 1675, 1630, 1610, 1250 Elemental analysis for C 21 H 28 O 10 Calculated (%) C 57.26; H 6.41; O 36.33 Found (%) C 57.40; H 6.40; O 36.20 Compound 88 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.10 (bs, 1H), 7.62 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.20 (bs, 1H), 4.98 (d, 1H, J=7.6Hz), 4.90(bs, 1H), 4.65 (bs, 1H), 4.52 (bs, 1H), 4.52 (t, 2H, J=6.6Hz), 3.64∼3.24 (m, 6H), 1.80∼1.15 (m, 12H), 0.89 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3450, 2940, 2910, 2850, 1675, 1630, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.96; H 6.89; O 34.15 Found (%) C 58.90; H 6.93; O 34.17 Compound 89 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.15 (bs, 1H), 7.60 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.20 (bs, 1H), 4.95 (d, 1H, J=7.6Hz), 4.90 (bs, 1H), 4.68 (bs, 1H), 4.52 (bs, 1H), 4.49 (t, 2H, J=6.6Hz), 3.64∼3.24 (m, 6H), 1.81∼1.20 (m, 16H), 0.92 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3400, 2940, 2900, 2850, 1670, 1630, 1610, 1250 Elemental analysis for C 25 H 36 O 10 Calculated (%) C 60.47; H 7.31; O 32.22 Found (%) C 60.40; H 7.40; O 32.20 Compound 90 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.20 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.01 (m, 2H), 5.24 (bs, 1H), 4.91 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.65 (bs, 1H), 4.50 (bs, 1H), 4.49 (t, 2H, J=6.6Hz), 3.65∼3.25 (m, 6H), 1.79∼1.20 (m, 20H), 0.88 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2945, 2920, 2850, 1675, 1630, 1600, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81; H 7.69; O 30.50 Found (%) C 61.75; H 7.50; O 30.75 Compound 91 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.30 (bs, 1H), 7.59 (d, 1H, J=9.6Hz), 7.12∼7.02 (m, 2H), 5.20 (bs, 1H), 4.93 (d, 1H, J=7.6Hz), 4.85 (bs, 1H), 4.67 (bs, 1H), 4.49 (m, 2H), 3.65∼3.25 (m, 6H), 1.04 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3400, 2960, 2930, 2850, 1690, 1635, 1610, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27; H 5.57; O 40.16 Found (%) C 54.17; H 5.57; O 40.26 Compound 92 1 H-NMR (CDCl 3 , δ-TMS) : 10.40 (bs, 1H), 7.60 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.20 (bs, 1H), 5.03 (m, 1H), 4.90 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.66 (bs, 1H), 4.55 (bs, 1H), 3.63∼3.23 (m, 6H), 2.19∼1.13 (m, 9H), 0.95 (d, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3340, 2970, 2920, 2850, 1680, 1635, 1610, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40; H 6.24; O 35.36 Found (%) C 58.35; H 6.30; O 35.35 Compound 93 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.85 (bs, 1H), 7.59 (d, 1H, J=9.6Hz), 7.09∼6.99 (m, 2H), 6.45 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.20 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.68 (bs, 1H), 4.52 (bs, 1H), 4.15 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.93 (dd, 1H, J=9.5Hz, J=2.0Hz), 3.64∼3.24 (m, 6H), IR (KBr, cm -1 ) : 3360, 2950, 2900, 2850, 1670, 1630, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40; H 4.75; O 41.85 Found (%) C 53.51; H 4.78; O 41.71 Compound 94 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.73 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.11∼7.01 (m, 2H), 5.50 (m, 1H), 5.35 (m. 1H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.91 (bs, 1H), 4.67 (bs, 1H), 4.50 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.65∼3.25 (m, 6H), 2.33∼1.97 (m, 4H), 0.99 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3340, 2950, 2920, 1710, 1630, 1605, 1260 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53; H 5.98; O 36.49 Found (%) C 57.67; H 5.95; O 36.38 Compound 95 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.29 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.09∼7.00 (m, 2H), 5.40 (m, 1H), 5.21 (bs, 1H), 5.11 (m, 1H), 4.94 (d, 1H, J=7.6Hz), 4.86 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.15 (d, 2H, J=8.5Hz), 3.66∼3.26 (m, 6H), 2.01 (m, 4H),1.67 (s, 6H), 1.64 (s, 3H) IR (KBr, cm -1 ) : 3350, 2950, 2915, 1700, 1660, 1605, 1260 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96; H 6.55; O 32.49 Found (%) C 60.93; H 6.62; O 32.45 Compound 96 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.13 (bs, 1H), 7.60 (d, 1H, J=9.6Hz), 7.34 (m, 5H), 7.10∼7.05 (m, 2H), 5.28 (s, 2H), 5.19 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.90 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 3.65∼3.24 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2930, 2840, 1700, 1620, 1260 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19; H 4.97; O 35.84 Found (%) C 59.28; H 4.85; O 35.87 Compound 97 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.55 (s, 1H), 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 3H), 2.34 (s, 3H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 3320, 2950, 1750, 1620, 1370, 1240 Elemental analysis for C 25 H 26 O 15 Calculated (%) C 53.00 H 4.59 O 42.41 Found (%) C 52.95 H 4.55 O 42.50 Compound 98 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 3H), 4.15 (s, 3H), 2.34 (s, 3H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 26 H 28 O 15 Calculated (%) C 53.79 H 4.83 O 41.38 Found (%) C 53.85 H 4.79 O 41.36 Compound 99 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.46 (t, 2H, J=6.0Hz), 4.40∼4.10 (m, 3H), 2.25 (q, 2H, J=7.2Hz), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 1.80∼1.70 (m, 2H), 1.55∼1.40 (m, 2H), 1.05 (t, 3H, J=7.2Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 2920, 2850, 1730, 1640, 1610, 1260 Elemental analysis for C 30 H 36 O 15 Calculated (%) C 56.60 H 5.66 O 37.74 Found (%) C 56.55 H 5.79 O 37.66 Compound 100 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.35∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.30∼5.18 (m, 8H),5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.46 (t, 2H, J=6.0Hz), 4.40∼4.10 (m, 3H), 2.25 (q, 2H, J=7.2Hz), 1.95∼1.40 (m, 16H), 1.07 (t, 3H, J=7.2Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1725, 1640, 1610, 1250 Elemental analysis for C 56 H 64 O 11 Calculated (%) C 73.68; H 7.02; O 19.30 Found (%) C 73.65; H 7.05; O 19.30 Compound 101 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.40∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.30∼5.18 (m, 8H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.46 (t, 2H, J=6.0Hz), 4.40∼4.10 (m, 3H), 2.05∼1.40 (m, 20H), 1.05 (t, 3H, J=7.4Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 58 H 68 O 11 Calculated (%) C 74.04 H 7.23 O 18.73 Found (%) C 74.08 H 7.35 O 18.57 Compound 102 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.40∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.30∼5.18 (m, 8H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 4H), 2.25 (s, 3H), 1.05 (d, J=7.5Hz, 6H) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1610, 1250 Elemental analysis for C 48 H 48 O 11 Calculated (%) C 72.00 H 6.00 O 22.00 Found (%) C 71.95 H 5.96 O 22.09 Compound 103 1 H-NMR (CDCl 3 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.99 (m, 1H), 4.40∼4.10 (m, 3H), 2.34 (s, 3H), 2.20∼1.25 (m, 9H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 0.98 (d, 3H, J=6.4Hz) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 32 H 38 O 15 Calculated (%) C 58.00, H 5.74 O 36.26 Found (%) C 57.95 H 5.79 O 36.26 Compound 104 1 H-NMR (DMSO-d 6 , δ-TMS) : 77.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 6.45 (dd, 1H, J=17Hz, J=9.5Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz),5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 4H), 3.95 (dd, 1H, J=9.5Hz), J=2.0Hz), 2.34 (s, 3H),2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1605, 1250 Elemental analysis for C 27 H 28 O 15 Calculated (%) C 54.73 H 4.73 O 40.54 Found (%) C 54.85 H 4.69 O 40.46 Compound 105 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.34 (m, 2H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 5H), 2.34 (s, 3H), 2.30∼1.95 (m, 4H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2950, 2850, 1720, 1610, 1250 Elemental analysis for C 31 H 36 O 15 Calculated (%) C 57.41 H 5.56 O 37.03 Found (%) C 57.45 H 5.59 O 36.96 Compound 106 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.11 (m, 2H), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.22 (m, 3H), 4.10 (d, 2H, J= 8.5Hz), 2.30 (m, 4H), 2.05 (m, 2H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 1.85 (m, 2H), 1.67 (s, 6H), 1.60 (s, 3H), 1.55 (m, 2H), 1.05 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1620, 1260 Elemental analysis for C 37 H 46 O 15 Calculated (%) C 60.82; H 6.30; O 32.88 Found (%) C 60.85; H 6.35; O 32.80 Compound 107 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.35∼7.15 (m, 25H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.20∼5.35 (m, 10H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.15 (m, 3H), 2.30 (t, 2H, J=6.8Hz), 1.55 (m, 2H), 1.05 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 2850, 1705, 1620, 1260 Elemental analysis for C 54 H 52 O 11 Calculated (%) C 73.97; H 5.94; O 20.09 Found (%) C 73.95; H 5.96; O 20.09 Compound 108 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.45 (s, 1H, 9.19 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.37 (bs, 1H), 5.11 (bs, 1H),5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 3.75∼3.10 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1600, 1260 Elemental analysis for C 15 H 16 O 10 Calculated (%) C 50.56 H 4.53 O 44.91 Found (%) C 50.55 H 4.49 O 44.96 Compound 109 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.25 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.35 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.23 (s, 3H), 3.75∼3.10 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1610, 1250 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.85 H 4.79 O 43.36 Compound 110 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.19 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.37 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.25 (t, 2H, J=6.2Hz), 3.75∼3.10 (m, 6H), 1.80∼1.20 (m, 4H), 0.85 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1700, 1640, 1610, 1260 Elemental analysis for C 19 H 24 O 10 Calculated (%) C 55.33 H 5.87 O 38.80 Found (%) C 55.25 H 5.89 O 38.86 Compound 111 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.10 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.37 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.59 (bs, 1H), 4.40 (t, 2H, J=6.4Hz), 3.75∼3.10 (m, 6H), 1.80∼1.60 (m, 2H), 1.52∼1.15 (m, 14H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 25 H 36 O 10 Calculated (%) C 60.47; H 7.31; O 32.22 Found (%) C 60.35; H 7.45; O 32.20 Compound 112 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.60 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.37 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.95 (d, 1H, J=7.2Hz), 4.59 (bs, 1H), 4.25 (t, 2H, J=6.4Hz), 3.75∼3.10 (m, 6H), 1.80∼1.60 (m, 2H), 1.52∼1.12 (m, 18H), 0.85 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81; H 7.69; O 30.50 Found (%) C 61.75; H 7.45; O 30.80 Compound 113 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.25 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.35 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.45 (m, 1H), 3.75∼3.10 (m, 6H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1610, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27 H 5.57 O 40.16 Found (%) C 54.18 H 5.69 O 40.13 Compound 114 1 H-NMR (CDCl 3 , δ-TMS) : 9.25 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.35 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 5.00 (m, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 3.75∼3.10 (m, 6H), 2.02∼1.20 (m, 9H), 0.98 (d, 3H, J=6.5Hz) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1610, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40 H 6.24 O 35.36 Found (%) C 58.45 H 6.29 O 35.26 Compound 115 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.25 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 6.55 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.35 (bs, 1H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.16 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.95 (dd, 1H, J=9.5Hz, J=2.0Hz) , 3.75∼3.10 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40 H 4.75 O 41.85 Found (%) C 53.55 H 4.79 O 41.66 Compound 116 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.19 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.55 (m, 1H), 5.34 (m, 2H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.75∼3.10 (m, 6H), 2.30∼1.95 (m, 4H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 1700, 1640, 1605, 1260 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53 H 5.98 O 36.49 Found (%) C 57.75 H 5.79 O 36.46 Compound 117 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.10∼7.00 (m, 2H), 5.40 (m, 1H), 5.37 (bs, 1H), 5.11 (m, 2H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 4.12 (d, 2H, J=8.5Hz), 3.75∼3.10 (m, 6H), 2.05 (m, 4H), 1.67 (s, 6H), 1.60 (s, 3H) IR (KBr, cm -1 ) : 3350, 2950, 2920, 1700, 1640, 1605, 1260 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96 H 6.55 O 32.49 Found (%) C 60.85 H 6.75 O 32.40 Compound 118 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.19 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.35∼7.20 (m, 5H), 7.10∼7.00 (m, 2H), 5.37 (bs, 1H), 5.25 (s, 2H), 5.11 (bs, 1H), 5.05 (bs, 1H), 4.96 (d, 1H, J=6.8Hz), 4.59 (bs, 1H), 3.75∼3.10 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1620, 1260 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19 H 4.97 O 35.84 Found (%) C 59.25 H 4.79 O 35.96 Compound 119 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.55 (s, 1H), 7.77 (d, 1H, J=8.8Hz), 7.30∼7.15 (m, 2H), 5.94 (s, 1H), 5.45∼5.35 (m, 2H), 5.13 (t, 1H, J=10.0Hz), 4.20∼3.90 (m, 3H), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 3320, 2950, 1750, 1620, 1370, 1240 Elemental analysis for C 25 H 26 O 15 Calculated (%) C 53.00 H 4.59 O 42.41 Found (%) C 52.95 H 4.55 O 42.50 Compound 120 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.30∼7.15 (m, 2H), 5.94 (s, 1H), 5.45∼5.35 (m, 2H), 5.13 (t, 1H, J=10Hz),4.20∼3.90 (m, 3H), 4.15 (s, 3H), 2.34 (s, 3H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 26 H 28 O 15 Calculated (%) C 53.79 H 4.83 O 41.38 Found (%) C 53.85 H 4.79 O 41.36 Compound 121 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.30∼7.15 (m, 22H), 5.94 (s, 1H), 5.45∼5.35 (m, 2H), 5.25 (m, 8H), 5.13 (t, 1H, J=10.0Hz), 4.20∼3.90 (m, 3H), 4.46 (t, 2H, J=6.0Hz), 2.25 (q, 2H, J=7.2Hz), 1.80∼1.40 (m, 12H), 1.05 (t, 3H, J=7.2Hz), 0.95 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 2920, 2850, 1730, 1640, 1610, 1260 Elemental analysis for C 54 H 60 O 11 Calculated (%) C 73.30 H 6.78 O 19.92 Found (%) C 73.35 H 6.80 O 19.85 Compound 122 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.35∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.94 (s, 1H), 5.45∼5.35 (m, 2H), 5.30∼5.18 (m, 8H), 5.13 (t, 1H, J=10.0Hz), 4.20∼3.90 (m, 3H), 4.46 (t, 2H, J=6.0Hz), 2.23 (q, 2H, J=7.0Hz), 1.95∼1.40 (m, 16H), 1.07 (t, 3H, J=7.0Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1725, 1640, 1610, 1250 Elemental analysis for C 56 H 64 O 11 Calculated (%) C 73.68 H 7.02 O 19.30 Found (%) C 73.65 H 7.05 O 19.30 Compound 123 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.40∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.30∼5.18 (m, 8H) 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.46 (t, 2H, J=6.0Hz), 4.40∼4.10 (m, 3H), 2.34 (s, 3H), 2.26 (q, 2H, J=7.0Hz), 2.05∼1.40 (m, 20H), 1.05 (t, 3H, J=7.0Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 58 H 68 O 11 Calculated (%) C 74.04 H 7.23 O 18.73 Found (%) C 74.08 H 7.35 O 18.57 Compound 124 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.40∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.18∼5.30 (m, 8H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 4H), 2.25 (s, 3H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1610, 1250 Elemental analysis for C 48 H 48 O 11 Calculated (%) C 72.00 H 6.00 O 22.00 Found (%) C 71.95 H 5.96 O 22.09 Compound 125 1 H-NMR (CDCl 3 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.30∼7.15 (m, 2H), 5.94 (s, 1H), 5.45∼5.35 (m, 2H), 5.13 (t, 1H, J=10.0Hz), 5.05 (m, 1H), 4.20∼3.90 (m, 3H), 2.34 (s, 3H), 2.20∼1.25 (m, 9H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 0.95 (d, 3H, J=6.6Hz) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 32 H 38 O 15 Calculated (%) C 58.00 H 5.74 O 36.26 Found (%) C 58.04 H 5.79 O 36.17 Compound 126 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.30∼7.15 (m, 2H), 5.94 (s, 1H), 6.45 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.45∼5.35 (m, 2H), 5.13 (t, 1H, J=10.0Hz), 4.20∼3.90 (m, 5H), 2.34 (s, 3H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 27 H 28 O 15 Calculated (%) C 54.73 H 4.73 O 40.54 Found (%) C 54.75 H 4.79 O 40.46 Compound 127 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.34 (m, 2H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 5H), 2.34 (s, 3H), 2.30∼1.95 (m, 4H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1610, 1250 Elemental analysis for C 31 H 36 O 15 Calculated (%) C 57.41 H 5.56 O 37.03 Found (%) C 57.45 H 5.59 O 36.96 Compound 128 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.11 (m, 2H), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.22 (m, 3H), 4.12 (d, 2H, J=8.5Hz), 2.30 (m, 4H), 2.05 (m, 2H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 1.67 (s, 6H), 1.60 (s, 3H), 1.55 (m,2H), 1.05 (t, 3H, J=6.9Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1620, 1260 Elemental analysis for C 37 H 46 O 15 Calculated (%) C 60.82 H 6.30 O 32.88 Found (%) C 60.85 H 6.35 O 32.80 Compound 129 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.35∼7.15 (m, 25H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.35∼5.20 (m,10H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.15 (m, 3H), 2.25 (t, 2H, J=6.9Hz), 1.56 (m, 2H), 1.04(t, 3H, J=6.9Hz) IR (KBr, cm -1 ) : 2950, 2850, 1705, 1620, 1260 Elemental analysis for C 54 H 52 O 11 Calculated (%) C 73.97 H 5.94 O 20.09 Found (%) C 73.98 H 5.96 O 20.06 Compound 130 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.15 (s, 1H), 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 3.85 (s, 1H), 3.75∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 15 H 16 O 10 Calculated (%) C 50.56 H 4.53 O 44.91 Found (%) C 50.52 H 4.55 O 44.93 Compound 131 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.20 (s, 3H), 3.85 (s, 1H), 3.75∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.83 H 4.85 O 43.32 Compound 132 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.20 (bs, 1H), 7.55 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.45 (t, 2H, J=6.4Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H), 1.80∼1.30 (m, 12H), 0.87 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 23 H 32 O 10 Calculated (%) C 58.96 H 6.89 O 34.15 Found (%) C 58.95 H 6.85 O 34.20 Compound 133 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.42 (t, 2H, J=6.4Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H), 1.80∼1.25 (m, 16H), 0.85 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 25 H 36 O 10 Calculated (%) C 60.47 H 7.31 O 32.22 Found (%) C 60.35 H 7.45 O 32.20 Compound 134 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.42 (t, 2H, J=6.4Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H), 1.90∼1.25 (m, 20H), 0.85 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81 H 7.69 O 30.50 Found (%) C 61.75 H 7.45 O 30.80 Compound 135 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.28 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.45 (m, 1H), 3.85 (s, 1H), 3.75∼3.10 (m, 6H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27 H 5.57 O 40.16 Found (%) C 54.10 H 5.65 O 40.25 Compound 136 1 H-NMR (CDCl 3 , δ-TMS) : 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.99 (m, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 3.75∼3.20 (m, 6H), 2.20∼1.25 (m, 9H), 0.95 (d, 3H, J=6.7Hz) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40 H 6.24 O 35.36 Found (%) C 58.43 H 6.35 O 35.22 Compound 137 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 6.45 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.15 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.95 (dd, 1H, J=9.5Hz, J=2.0Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40 H 4.75 O 41.85 Found (%) C 53.33 H 4.80 O 41.87 Compound 138 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.55 (m, 1H), 5.34 (m, 2H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H), 2.30∼1.95 (m, 4H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53 H 5.98 O 36.49 Found (%) C 57.57 H 5.85 O 36.58 Compound 139 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.41 (m, 1H), 5.13 (m, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 4.12 (d, 2H, J=8.5Hz), 3.85 (s, 1H), 3.75∼3.20 (m, 6H), 2.05 (m, 4H), 1.67 (s, 6H), 1.60 (s, 3H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96 H 6.55 O 32.49 Found (%) C 60.89 H 6.65 O 32.36 Compound 140 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.15 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.35 (m, 5H), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.23 (s, 2H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 3.85 (s, 1H), 3.75∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3335, 2950, 2920, 2850, 1690, 1630, 1610, 1250 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19 H 4.97 O 35.84 Found (%) C 59.25 H 4.79 O 35.96 Compound 141 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.25 (bs, 1H), 7.77 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 4.52(t, 1H, J=6.6Hz), 4.11 (d, 2H, J=6.0Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.96 (s, 3H) IR (KBr, cm -1 ) : 2950, 1750, 1620, 1370, 1240 Elemental analysis for C 25 H 26 O 15 Calculated (%) C 53.00 H 4.59 O 42.41 Found (%) C 52.95 H 4.55 O 42.50 Compound 142 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 4.52 (t, 1H, J=6.6Hz), 4.25 (s, 3H), 4.11 (d, 2H, J=6.0Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.96 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 26 H 28 O 15 Calculated (%) C 53.79 H 4.83 O 41.38 Found (%) C 53.85 H 4.79 O 41.36 Compound 143 1 H-NMR (DMSO-d 6 , δ-TMS) ; 7.77 (d, 1H, J=8.8Hz), 7.35∼7.20 (m, 20H), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 5.30∼5.18 (m, 8H), 4.52 (t, 1H, J=6.6Hz), 4.46 (t, 2H, J=6.0Hz), 4.11 (d, 2H, J=6.0Hz), 1.95∼1.40 (m, 16H), 2.30 (q, 2H, J=7.1Hz), 1.10 (t, 3H, J=7.1Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1725, 1640, 1610, 1250 Elemental analysis for C 56 H 64 O 11 Calculated (%) C 73.68 H 7.02 O 19.30 Found (%) C 73.65 H 7.05 O 19.30 Compound 144 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.35∼7.20 (m, 20H), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 5.30∼5.18 (m, 8H), 4.52 (t, 1H, J=6.6Hz), 4.38 (t, 2H, J=6.0Hz), 4.11 (d, 2H, J=6.0Hz), 2.25 (q, 2H, J=7.2Hz), 1.95∼1.40 (m, 20H), 1.10 (t, 3H, J=7.2Hz), 0.93 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2920, 2850, 1700, 1640, 1610, 1250 Elemental analysis for C 58 H 68 O 11 Calculated (%) C 74.04 H 7.23 O 18.73 Found (%) C 74.08 H 7.35 O 18.57 Compound 145 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.40∼7.20 (m, 20H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.30∼5.18 (m, 8H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 4H), 2.25 (s, 3H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1610, 1250 Elemental analysis for C 48 H 48 O 11 Calculated (%) C 72.00 H 6.00 O 22.00 Found (%) C 71.95 H 5.96 O 22.09 Compound 146 1 H-NMR (CDCl 3 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 5.02 (m, 1H), 4.52 (t, 1H, J=6.6Hz), 4.11 (d, 2H, J=6.0Hz), 2.34 (s, 3H), 2.25∼1.24 (m, 9H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.96 (s, 3H), 0.97 (d, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 32 H 38 O 15 Calculated (%) C 58.00 H 5.74 O 36.26 Found (%) C 57.95 H 5.79 O 36.26 Compound 147 1 H-NMR (DMSO-d 6 , δ-TMS) ; 7.77 (d, 1H, J=8.8Hz), 7.11 (d, 1H, J=2.4Hz), 7.05 (dd, 1H, J=2.4Hz, J=8.8Hz), 6.44 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.66 (d, 1H, J=7.2Hz), 5.38 (d, 1H, J=2.4Hz), 5.30∼5.20 (m, 2H), 4.52 (t, 1H, J=6.6Hz), 4.20 (dd, 1H, J=17.5Hz, J=2.0Hz), 4.11 (d, 2H, J=6.0Hz), 3.96 (dd, 1H, J=9.5Hz, J=2.0Hz), 2.34 (s, 3H), 2.16 (s, 3H), 2.05 (s, 3H), 2.02 (s, 3H), 1.96 (s, 3H) IR (KBr, cm -1 ) : 2950, 2850, 1725, 1610, 1250 Elemental analysis for C 27 H 28 O 15 Calculated (%) C 54.73 H 4.73 O 40.54 Found (%) C 54.85 H 4.79 O 40.36 Compound 148 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.77 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.34 (m, 2H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.10 (m, 5H), 2.34 (s, 3H), 2.30∼1.95 (m, 4H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1610, 1250 Elemental analysis for C 31 H 36 O 15 Calculated (%) C 57.41 H 5.56 O 37.03 Found (%) C 57.45 H 5.59 O 36.96 Compound 149 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.11 (m, 2H), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.22 (m, 3H), 4.12 (d, 2H, J=8.5Hz), 2.35 (m, 4H), 2.05 (m, 2H), 2.04 (s, 3H), 2.03 (s, 3H), 2.02 (s, 3H), 1.99 (s, 3H), 1.67 (s, 6H), 1.60 (s, 3H), 1.55 (m, 2H), 1.00 (t, 3H, J=6.8Hz) IR (KBr, cm -1 ) : 2950, 2850, 1735, 1620, 1260 Elemental analysis for C 37 H 46 O 15 Calculated (%) C 60.82 H 6.30 O 32.88 Found (%) C 60.85 H 6.35 O 32.80 Compound 150 1 H-NMR (DMSO-d 6 , δ-TMS) : 7.65 (d, 1H, J=8.8Hz), 7.35∼7.15 (m, 25H), 7.12 (d, 1H, J=2.4Hz), 7.06 (dd, 1H, J=2.4Hz, J=8.8Hz), 5.74 (d, 1H, J=7.6Hz), 5.41 (t, 1H, J=9.4Hz), 5.35∼5.20 (m, 10H), 5.13 (dd, 1H, J=7.6Hz, J=9.6Hz), 5.04 (t, 1H, J=9.8Hz), 4.40∼4.15 (m, 3H), 2.25 (t, 2H, J=7.0Hz), 1.55 (m, 2H), 1.00 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 2950, 2850, 1705, 1620, 1260 Elemental analysis for C 54 H 52 O 11 Calculated (%) C 73.97 H 5.94 O 20.09 Found (%) C 73.94 H 5.96 O 20.10 Compound 151 1 H-NMR (DMSO-d 6 , δ-TMS) : 10.24 (bs,1H), 9.17 (bs, 1H), 7.61 (d, 1H, J=8.8Hz), 7.12 (d, 1H, J=2.4Hz), 7.07 (dd, 1H, J=2.2Hz, J=9.0Hz), 5.47 (s, 1H), 5.07 (bs, 1H), 4.85 (bs, 1H), 4.77 (bs, 1H), 3.85 (s, 1H), 3.75∼3.20 (m, 6H) IR (KBr, cm -1 ) : 3400, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 15 H 16 O 10 Calculated (%) C 50.56 H 4.53 O 44.91 Found (%) C 50.52 H 4.55 O 44.93 Compound 152 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.35 (m, 5H), 7.10∼7.00 (m, 2H), 5.28 (s, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs,1H), 3.65∼3.25 (m, 6H) IR (KBr, cm -1 ) : 3330, 3300, 2950, 2850, 1700, 1620, 1260 Elemental analysis for C 22 H 22 O 10 Calculated (%) C 59.19 H 4.97 O 35.84 Found (%) C 59.33 H 4.89 O 35.78 Compound 153 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.23 (s, 3H), 3.65∼ 3.25 (m, 6H) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 16 H 18 O 10 Calculated (%) C 51.89 H 4.90 O 43.21 Found (%) C 51.85 H 4.78 O 43.37 Compound 154 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.47 (t, 2H, J=6.6Hz), 3.65∼3.25 (m, 6H), 1.80∼1.70 (m, 2H), 1.60∼1.20 (m, 14H), 0.90 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3400, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 25 H 36 O 10 Calculated (%) C 60.47 H 7.31 O 32.22 Found (%) C 60.45 H 7.40 O 32.15 Compound 155 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.10 (bs, 1H), 7.60 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.65 (bs, 1H), 4.52 (bs, 1H), 4.47 (t, 2H, J=6.6Hz), 3.65∼3.25 (m, 6H), 1.80∼1.70 (m, 2H), 1.60∼1.20 (m, 18H),0.90 (t, 3H, J=7.2Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 27 H 40 O 10 Calculated (%) C 61.81 H 7.69 O 30.50 Found (%) C 61.75 H 7.45 O 30.80 Compound 156 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.50 (m, 2H), 3.65∼3.25 (m, 6H), 1.05 (d, 6H, J=7.5Hz) IR (KBr, cm -1 ) : 3400, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 18 H 22 O 10 Calculated (%) C 54.27 H 5.57 O 40.16 Found (%) C 54.07 H 5.67 O 40.26 Compound 157 1 H-NMR (CDCl 3 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.21 (bs, 1H), 5.00 (m, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 3.65∼3.25 (m, 6H), 2.20∼1.14 (m, 9H), 0.96 (d, 2H, J=6.8Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 22 H 28 O 10 Calculated (%) C 58.40 H 6.24 O 35.36 Found (%) C 58.25 H 6.38 O 35.37 Compound 158 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 6.45 (dd, 1H, J=17.5Hz, J=9.5Hz), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.15 (dd, 1H, J=17.5Hz, J=2.0Hz), 3.96 (dd, 1H, J=9.5Hz, J=2.0Hz), 3.65∼3.25 (m, 6H) IR (KBr, cm -1 ) : 3350, 2950, 2920, 2850, 1680, 1630, 1610, 1250 Elemental analysis for C 17 H 18 O 10 Calculated (%) C 53.40 H 4.75 O 41.85 Found (%) C 53.45 H 4.78 O 41.77 Compound 159 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.55 (m, 1H), 5.34 (m, 1H), 5.21 (bs, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.27 (t, 2H, J=6.2Hz), 3.65∼3.25 (m, 6H), 2.30∼1.95 (m, 4H), 0.97 (t, 3H, J=7.0Hz) IR (KBr, cm -1 ) : 3350, 2950, 2920, 1700, 1640, 1605, 1260 Elemental analysis for C 21 H 26 O 10 Calculated (%) C 57.53 H 5.98 O 36.49 Found (%) C 57.77 H 5.85 O 36.38 Compound 160 1 H-NMR (DMSO-d 6 , δ-TMS) : 9.16 (bs, 1H), 7.61 (d, 1H, J=9.6Hz), 7.10∼7.00 (m, 2H), 5.40 (m, 1H), 5.21 (bs, 1H), 5.11 (m, 1H), 4.92 (d, 1H, J=7.6Hz), 4.88 (bs, 1H), 4.67 (bs, 1H), 4.52 (bs, 1H), 4.15 (d, 2H, J=8.5Hz), 3.65∼3.25 (m, 6H), 2.05 (m, 4H), 1.67 (s, 6H), 1.60 (s, 3H) IR (KBr, cm -1 ) : 3350, 2950, 2920, 1700, 1640, 1605, 1260 Elemental analysis for C 25 H 32 O 10 Calculated (%) C 60.96 H 6.55 O 32.49 Found (%) C 60.83 H 6.62 O 32.55 TEST EXAMPLE 1 Acute toxicity test in mice We performed this test in order to comfirm a degree of the safety on that the compounds of the present invention. In the following, the method of the acute toxicity test will be explained. Method:7-glycosyloxybenzopyran derivatives (compound No. 3, 8, 9, 11, 15, 16, 18 ∼ 23, 35, 37 ∼ 47, 61 ∼ 72, 75, 86 ∼ 96, 99, 108 ∼ 118, 130 ∼ 140, 145, 151 ∼ 160) were forcibly administered orally at the doses of 1000 and 2000 mg/kg to Male ICR mice (body weight is 20 ∼ 25 g, 5 mice per one(1) group), using an esophageal sound. After the administration, the animals were kept in cages for 7 days, to observed general symptoms and to count dead animals. Lethal dose (LD 50 :mg/kg) was extrapolated from the mortality at 7th day after administration. In result, the LD 50 of all 7-glycosyloxybenzopyran derivatives were over 2000 mg/kg, and therefore it was clearly shown that the compounds of the present invention have extremely low toxicity. TEST EXAMPLE 2 Effect on homologous passive cutaneous anaphylaxis (PCA) reaction in rats. We performed this pharmacological test by PCA reaction which was well known screening test for anti-allergic agents in order to demonstrate that the compounds of the present invention possess anti-allergic activity. This experimental animal model is caused by immediate type allergic reaction namely, antigen-antibody reaction. In the following, the method of this pharmacological test will be explained. Method : Male wistar rats (9 weeks old) were intradermally administered 0.05 ml of anti-serum against dinitrophenylated ascaris (DNP-As) into two sites on the shaved dorsal skin. 48 hours later, 7-glycosyloxybenzopyran derivatives (test compounds) suspended in 0.5 % sodium carboxymethylcellulose (CMCNa) were given orally at a dose of 50 mg/kg to the animals. One hour after administration of Test compounds, the animals were induced anaphylaxis by injection of saline (1 ml) dissolving 5 mg of Evans Blue and 1 mg of Trinitrophenylated ascaris (TNP-As) into the tail vein of the animals. 30 minutes after induction of anaphylaxis, animals were anesthetized by ether and killed by bleeding, and were flayed dorsal skin. The determination of extravasated dye was performed according to the method of Katayama et al. (Microbiol. Immunol., Vol.22, P 89-101, 1978). As vehicle control group, only 0.5 % CMCNa solution was administered orally, and as positive control group, Tranilast suspended in 0.5 % CMCNa was administered orally at a dose of 100 mg/kg to the animals with the same method as the test compounds groups. Inhibition (%) of PCA reaction was calculated according to equation 1 and the result was shown in TABLE 2. Each experimental group consisted of 5 rats. Inhibition (%) = A-B A ×100 In equation 1 : A : amount of dye in vehicle control group B : amount of dye in test compound group or in positive control group As shown in table 2, it was demonstrated that all compounds of the present invention have equivalent or superior anti-allergic activity to Tranilast. The results of these examples clearly showed that the compounds of the present invention were useful anti-allergic agent for immediate type allergic disease. COMPARATIVE TEST EXAMPLE 1 Effect on homologous passive cutaneous anaphylaxis (PCA) reaction in rats The anti-allergic activity of the compounds of the present invention were compared with that of analogous compounds which were published in the Patent (No. WO 92 / 13852) by PCA reaction. This pharmacological test was performed according to the method described in Test Example 2. The compared compounds were shown in table 3 and the results were shown in table 4. Compared compound No. Chemical name Compared compound 1 4-hydroxy-3,7-dimethoxy-2H-1-benzopyran-2-one Compared compound 2 3-butoxy-4-hydroxy-7-methoxy-2H-1-benzopyran-2-one Compared compound 3 3-hydroxy-4,7-dimethoxy-2H-1-benzopyran-2-one Compared compound 4 3-hydroxy-4-butoxy-7-methoxy-2H-1-benzopyran-2-one Compared compound No. Inhibition (%) compound No. (of the present invention) Inhibition (%) Compared compound 1 28.1 compound 3 53.1 Compared compound 2 32.4 compound 9 54.5 compound 37 55.1 compound 86 56.4 Compared compound 3 31.5 compound 109 42.1 Compared compound 4 26.2 compound 153 42.4 compound 110 41.4 compound 18 42.5 From the results of the Test Example 2 and this Comparative Test Example, it is clear that the anti-allergic activity of the compounds of the present invention, 7-glycoside, were higher than that of the compared compounds. TEST EXAMPLE 3 Effect on contact dermatitis induced by picryl chloride in mice We performed this pharmacological test by experimental contact dermatitis model which is well known in order to demonstrate that the compounds of the present invention suppress the delayed type hypersensitization. This experimental animal model which is typical delayed type hypersensitization model, was mainly caused by cellular immune response (Immunology, Vol. 15, P. 405 - 416, 1968). The delayed type hypersensitization is inhibited by steroid drugs,but can not be effected by known anti-allergic agents. In the following, the method of the pharmacological test will be explained. Method : Mice, shaved their abdominal skin on previous day, were immunized by applying 0.1 ml of acetone containing 7 mg of picryl chloride to the skin of the abdomen. 7 days after immunization, the thickness of the ear was measured with a dial thickness gauge, then mice were challenged by painting 5 µl of 1 % picryl chloride olive oil solution to each side skin of left ear. 24 hours after challenge, the thickness of the left ear was measured again and the increase (%) of thickness was calculated according to equation 2. The compounds of the present invention (test compounds) suspended in 0.5 % CMCNa were forcibly administered orally at a dose of 50 mg/kg at 1 hour before and 16 hours after challenge. As vehicle control group, only 0.5 % CMCNa solution were administered orally, and as positive control group, Prednisolone, steroid hormone, and Tranilast were administered orally at the doses of 10 mg/kg and 100 mg/kg, respectively. The inhibition (%) against the increase of thickness in vehicle control group were calculated according to equation 2 and 3, the result was shown in TABLE 5. Increase (%) = (A - B)/B × 100 In equation 2 : A : thickness of the ear at 24 hours after challenge B : thickness of the ear before challenge Inhibition (%) = (C - D)/C × 100 In equation 3 : C : The increase (%) in vehicle control group D : The increase (%) in test compounds group or positive control group It was observed that test compounds effectively inhibit the swelling of the ear by 40 to 65 % against that in vehicle control group. Many of the compounds of the present invention were equivalent or superior to Prednisolone (inhition : 63.7 %). In contrast, Tranilast, used widely for allergic disease, did not inhibit delayed type hypersensitization. These results clearly show that the compounds of the present invention have exceedingly inhibitory activity against delayed type hypersensitization. And therefore the compounds of the present inventionis are exceedingly useful anti-allergic agent. TEST EXAMPLE 4 Effect on exprimental asthma model in guinea pigs The asthma is typical allergic disease and we carried out this pharmacological test by well known experimental asthma model in guinea pigs in order to comfirm that the compounds of the present invention suppress the asthma. In the following, the method of the pharmacological test will be explained. Method : Male hartley guinea pigs were immunized by intraperitoneal injection of saline (1ml) containing 5 mg of ovalbumine (OVA) three times at interval of one week. 2 weeks after final immunization, the animals were challenged by inhalation of 1 % OVA-saline solution for 1 minute and then the airway resistance of the animals were measured for 30 minutes with PULMOS-1(Medical Interface Project Station Inc.) after the inhalation. The compounds of the present invention (test compounds) suspended in 0.5 % CMCNa were given orally at a dose of 50 mg/kg. As positive control group, Disodium Cromoglicate (DSCG), well known anti-allergic agent, in saline were injected at a dose of 20 mg/kg into the vein of the animals. As vehicle control group, only 0.5 % CMCNa solution were given orally. The inhibition (%) of the airway resistance in vehicle control group was calculated according to equation 5 and the result was shown in TABLE 6. Each experimental group consisted of 5 guinea pigs. Inhibition (%) = A-B A In equation 5 : A : Maximum airway resistance in vehicle control group B : Maximum airway resistance in test compounds group or positive control group As shown in Table 6, the compounds of the present invention administered orally inhibited the increase of the airway resistance by 40 ∼ 80 %. Therefore the compounds of the present invention have exceedingly high activity to treat for the asthma. FORMULATION EXAMPLE 1 (5% powders) compound 43 50 mg lactose 950 mg 1000 mg Crystals of the compound 43 were pulverized in a mortar and thoroughly mixed with by pulverizing the mixure with a pestle to obtain 5% powders. FORMULATION EXAMPLE 2 (5% powders) compound 154 50 mg lactose 950 mg 1000 mg The procedure of Formulation Example 1 was repeated to obtain 5% powders. FORMULATION EXAMPLE 3 (10% granules) compound 62 300 mg lactose 2000 mg starch 670 mg gelatin 30 mg 3000 mg The compound 62 was mixed with the same amount of starch and pulverized in a mortar. This was further mixed with lactose and the remaining portion of starch. Separately from this, 30 mg of gelatin was mixed with 1 ml of purified water, solubilized by heating, cooled and then, with stirring, mixed with 1 ml of ethanol to prepare a gelatin solution. Thereafter, the mixture prepared above was mixed with the gelatin solution, and the resulting mixture was kneaded, granulated and then dried to obtain granules. FORMULATION EXAMPLE 4 (10% granules) compound 132 300 mg lactose 2000 mg starch 670 mg gelatin 30 mg 3000 mg The procedure of Formulation Example 3 was repeated to obtain 10% granules. FORMULATION EXAMPLE 5 (5 mg tablets) compound 21 5 mg lactose 62 mg starch 30 mg talc 2 mg magnesium stearate 1 mg 100 mg/tablet A 20 times larger portion of the above composition was used to prepare tablets each of which containing 5 mg of the compound 21. That is, 100 mg of the compound 21 in a crystal form was pulverized in a mortar and mixed with lactose and starch. The thus prepared formulation was mixed with 10% starch paste, and the mixture was kneaded and then subjected to granulation. After drying, the resulting granules were mixed with talc and magnesium stearate and subjected to tablet making in the usual way. FORMULATION EXAMPLE 6 (5 mg tablets) compound 110 5 mg lactose 62 mg starch 30 mg talc 2 mg magnesium stearate 1 mg 100 mg/tablet The procedure of Formulation Example 5 was repeated to obtain 5 mg tablets. FORMULATION EXAMPLE 7 (20 mg tablets) compound 22 20 mg 6% hydroxypropylcellulose/lactose 75 mg stearate/talc 2 mg potato starch 3 mg 100 mg/tablet A 10 times larger portion of the above composition was used to prepare tablets each of which containing 20 mg of the active ingredient. That is, 6 g of hydroxypropylcellulose was dissolved in an appropriate volume of ethanol and mixed with 94 g of lactose, followed bykneading. After drying to a degree, the mixture was passed through a No.60 mesh, and the thus graded granules were used as 6% hydroxypropylcellulose/lactose. Separately from this, magnesium stearate and talc were mixed at a ratio 1:4 and used as stearate/talc. Thereafter, the compound 22, 6% hydroxypropylcellulose/lactose, stearate/talc and potato starch were thoroughly mixed and subjected to tablet making in the usual way. FORMULATION EXAMPLE 8 (20 mg tablets) compound 87 20 mg 6% hydroxypropylcellulose/lactose 75 mg stearate/talc 2 mg potato starch 3 mg 100 mg/tablet The procedure of Formulation Example 7 was repeated to obtain 20 mg tablets. FORMULATION EXAMPLE 9 (25 mg tablets) compound 68 25 mg lactose 122 mg carboxyethylstarch 50 mg talc 2 mg magnesium stearate 1 mg 200 mg/tablet Ten times larger portions of the above compounds were put into a mortar to prepare tablets each of which containing 25 mg of the active ingredient. That is, 250 mg of the compound 68 in a crystal form was pulverized in a mortar and thoroughly mixed with lactose. An appropriate volume of purified water was added to carboxyethylstarch which was subsequently added to the above mixture, and the resulting mixture was kneaded and then subjected to granulation. After drying, the thus prepared granules were mixed with talc and magnesium stearate and subjected to tablet making in the usual way. FORMULATION EXAMPLE 10 (25 mg tablets) compound 153 25 mg lactose 122 mg carboxyethylatarch 50 mg talc 2 mg magnesium stearate 1 mg 200 mg/tablet The procedure of Formulation Example 9 was repeated to obtain 25 mg tablets. FORMULATION EXAMPLE 11 (10 mg capsules) compound 38 300 mg lactose 2000 mg starch 670 mg gelatin 30 mg 3000 mg Granules were prepared in accordance with the procedure described in Formulation Example 3 and packed in capsules in 100 mg portions. FORMULATION EXAMPLE 12 (10 mg capsules) compound 116 300 mg lactose 2000 mg starch 670 mg gelatin 30 mg 3000 mg The procedure of Formulation Example 11 was repeated to obtain 100 mg capsules. FORMULATION EXAMPLE 13 (0.1% injections) compound 3 10 mg polyethylene glycol 400 3 ml polysorbate 80 0.01 ml distilled water for injection use balance 10 ml The compound 3 was dissolved in a mixture solution of polyethylene glycol 400 and polysorbate 80, total volume of the resulting solution was adjusted to 10 ml by gradually adding distilled water for injection use and then the thus prepared solution was packed in an ampule aseptically. FORMULATION EXAMPLE 14 (0.1% injections) compound 18 10 mg polyethylene glycol 400 3 ml polysorbate 80 0.01 ml distilled water for injection use balance 10 ml The procedure of Formulation Example 13 was repeated to obtain 0.1% injections. Thus, it is apparent that there has been provided, in accordance with the present invention, a novel 7-glycosyloxybenzopyran derivative which is useful in pharmaceutical preparations. Also provided are excellent antiallergic agents which have low toxicity and are useful for the treatment or prevention of immediate type and delayed type allergic diseases, particularly an excellent antiallergic agent which is highly effective on delayed type allergy that cannot be treated effectively with the prior art antiallergic agents. While the invention has been described in detail and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope thereof.

Claims: A 7-glycosyloxybenzopyran derivative represented by the following formula (I) wherein, R 1 is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group, R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group and R 3 is a glycosyl group whose hydroxyl group is protected or not protected, selected from the group consisting of glucosyl, mannosyl and galactosyl groups, and physiologically acceptable salts thereof. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1 wherein R 1 is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group and R 2 is a hydrogen atom or an aralkyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1 wherein R 1 is a hydrogen atom or an acyl group and R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1 wherein R 1 is a hydrogen atom, an alkyl group, a cycloalkyl group or an alkenyl group and R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group or an alkenyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in any one of claims 1 to 3 wherein the acyl group is an alkanoyl group and the aralkyl group is a benzyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2 or 4 wherein R 1 is an alkyl group having 1 to 12 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim1, 2 or 4 wherein R 1 is a cycloalkyl group having 5 to 8 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2 or 4 wherein R 1 is an alkenyl group having 2 to 10 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 4 wherein R 1 is an alkyl group having 1 to 12 carbon atoms, a cycloalkyl group having 5 to 8 carbon atoms or an alkenyl group having 2 to 10 carbon atoms and R 2 is a hydrogen atom. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 3 or 4 wherein R 2 is an alkyl group having 1 to 12 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim1, 3 or 4 wherein R 2 is a cycloalkyl group having 5 to 8 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 3 or 4 wherein R 2 is an alkenyl group having 2 to 10 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 4 wherein R 1 is a hydrogen atom and R 2 is an alkyl group having 1 to 12 carbon atoms, a cycloalkyl group having 5 to 8 carbon atoms or an alkenyl group having 2 to 10 carbon atoms. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2, 3, 4, 9 or 13 wherein R 3 is a glucosyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2, 3, 4, 9 or 13 wherein R 3 is a mannosyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2, 3, 4, 9 or 13 wherein R 3 is a galactosyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2, 3, 4, 9 or 13 wherein R 3 is an unprotected glycosyl group. The 7-glycosyloxybenzopyran derivative and physiologically acceptable salts thereof as claimed in claim 1, 2, 3, 4, 9 or 13 wherein R 3 is a glycosyl group which is protected with an acyl or aralkyl group. An antiallergic composition comprising a therapeutically effective amount of the compound of formula (I) as recited in claim 1, or a pysiologically acceptable salt thereof, and pharmaceutically acceptable carriers. The antiallergic composition as claimed in claim 19 wherein R 1 is a hydrogen atom, an alkyl group, a cycloalkyl group or an alkenyl group and R 2 is a hydrogen atom, an alkyl group, a cycloalkyl group or an alkenyl group. The antiallergic composition as claimed in claim 20 wherein R 1 is an alkyl group having 1 to 12 carbon atoms, a cycloalkyl group having 5 to 8 carbon atoms or an alkenyl group having 2 to 10 carbon atoms. The antiallergic composition as claimed in claim 20 wherein R 1 is a hydrogen atom and R 2 is an alkyl group, a cycloalkyl group or an alkenyl group. The antiallergic composition as claimed in claim 20 wherein R 1 is an alkyl group, a cycloalkyl group or an alkenyl group and R 2 is a hydrogen atom. The antiallergic composition as claimed in claim 23 wherein R 1 is an alkyl group having 1 to 12 carbon atoms. The antiallergic composition as claimed in claim 23 wherein R 1 is a cycloalkyl group having 5 to 8 carbon atoms. The antiallergic composition as claimed in claim 23 wherein R 1 is an alkenyl group having 2 to 10 carbon atoms. The antiallergic composition as claimed in any one of claims 19 to 26 wherein R 3 is a glucosyl group. The antiallergic composition as claimed in any one of claims 19 to 26 wherein R 3 is a mannosyl group. The antiallergic composition as claimed in any one of claims 19 to 26 wherein R 3 is a galactosyl group. The antiallergic composition as claimed in any one of claims 19 to 26 wherein R 3 is an unprotected glucosyl group. The antiallergic composition as claimed in any one of claims 19 to 26 wherein R 3 is a glycosyl group which is protected with an acyl or aralkyl group. A pharmaceutical composition comprising the compound of formula (I) as recited in claim 1 and nontoxic additives. A 7-glycosyloxybenzopyran derivative of formula (I) as recited in claim 1 or a physiologically acceptable salt for treating allergic diseases. Use of a compound represented by formula (I) as recited in claim 1 or a pysiologically acceptable salt thereof for preparing an agent for treating allergic diseases.

Inventors: ABE MASAYOSHI, AOKI YASUO E, KIMURA NOBUYUKI, SAKAI MITSURU, TAKAGAKI HIDETSUGU, ABE, MASAYOSHI, AOKI, YASUO E201, KIMURA, NOBUYUKI, SAKAI, MITSURU, TAKAGAKI, HIDETSUGU, ABE, MASAYOSHI, 2-30-4, ASUMIGAOKA, 1182-31, KIMURA, NOBUYUKI, 4-102, DAINIPPON INK SAKURA
Applicants: DAINIPPON INK & CHEMICALS, DAINIPPON INK AND CHEMICALS, INC.
Application year: 1995
Main classification: C07H17
IPC codes: C07H17, A61K31, A61P37