FUNGICIDAL IMIDAZOLINONES

Abstract: Imidazolinone compounds of formula (I), wherein: A is O; S or N-J; J is R<15>; C(=O)R<16>; C(=O)OR<17>; C(=O)SR<18>; C(=O)NR<19>R<20>; P(=O) (C1-C4 alkyl)2; or OG; G is H; C1-C6 alkyl; benzyl optionally substituted with R<34> on the phenyl ring; C(=O)(C1-C4 alkyl); C(=O)(C1-C4) alkoxy); or C(=O)NHR<36>; B is H; halogen; cyano; NC; S=C=N; O=C=N; nitro; R<21>; OR<29>; NR<49>R<63>; N=CR<45>R<46>; SR<47>; S(O)nR<48>; or SO2NR<49>R<60>; n is 1 or 2; R<1>, R<2>, R<3> and R<4> are various groups, are disclosed with compositions containing them and methods of their use.

Description: FUNGICIDAL IMIDAZOLINONES This invention relates to particular imidazolinone compounds useful as fungicides, agriculturally suitable compositions containing such compounds, and methods of use of such compounds or compositions as fungicides in crop plants. O90/12791 is drawn to the use of fungicidal compounds of Formula i wherein: A is 0 or NR 4 ; and is 0 or S. WO90/12791 also relates to processes for the preparation of compounds of Formula i and to certain novel compounds• The compounds of WO90/12791 are distinct from those of the present invention in that oxygen is incorporated into the central heterocyclic ring of compounds of Formula i and the bonds forming this five-membered ring are all single bonds. SUMMARY OF THE INVENTION This invention comprises compounds of Formula I including all geometric and stereoisomers thereof, agricultural compositions containing one or more such compounds, and methods of use of such compounds or compositions as f ngicides. The compounds of the present invention have the following structure: wherein: A is 0; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P(=0) (C 1 -C 4 alkyl) 2 ; or OG; G is H; C j^ -Cg alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C(=0) (C 1 -C 4 alkyl); C(=0) (C 1 -C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 2l . OR 29 ; NR 9 R 63 ; N=CR 45 R 46 ; SR 47 ; S(0) n R 48 ; or S0 2 NR 49 R 60 ; n is 1 or 2; R 1 is C 1 -C 4 alkyl; C 1 -C haloalkyl; C 3 -C 6 cycloalkyl; C 2 -C alkenyl; C 2 -C 4 alkoxycarbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is C 1 -C 20 alkyl optionally substituted with R 22 ; C 2 -C 20 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 0CH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 )CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of -CH (CH 2 ) CH 2 — f —CH 2 (CH ) 3 CH 2 —, — CH 2 (CH 2 ) CH 2 ~, —CH 2 CH 0CH CH 2 —, —CH 2 CH 2 SCH 2 CH 2 — , R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenylmethy1; R 4 is H or methyl; R 5 is halogen; nitro; cyano; C^Cg alkyl; C 5 -Cg cycloalkyl; C j^ -C haloalkyl; C 1 -Cg alkylthio; Ci-Cg haloalkylthio; C^Cg alkoxy; C^Cg haloalkoxy; C 5 -C 6 cycloalkyloxy; C _Cg alkoxyalkyl; C 2 -Cg alkoxyalkoxy; C 3 -Cg alkenyl; C 3 -Cg haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl; C 3 _C 6 haloalkynyl; C 3 -Cg alkynyloxy; c i~ c 6 alkylsulfonyl; Ci-Cg haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethy1, phenoxy- ethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC(=0)NHR 28 ; -C(=0)0R 28 ; or -0C(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; C 3 _-C 4 alkyl; trifluoro¬ methyl; methylthio; or C 1 -C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or C 1 -C 4 alkyl; R 9 is C j^ -C s alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C 1 _C alkyl, trifluoromethyl, C 1 -C 4 alkylthio, C 1 -C alkoxy and trifluoromethoxy; R 11 and R 36 are independently C^-Cg alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; C 1 -C 8 alkyl optionally substituted with C_-C 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; C 1 -C 17 alkyl optionally substituted with R 31 ; C 2 -C 17 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 4 -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C 2 -C 5 alkoxycarbonyl; R 17 and R 18 are independently C 1 -C 18 alkyl optionally substituted with R 23 ; C 2 -C 10 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; C 3 -C 1 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 6 -C 7 cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; Ci-Cio alkyl; C 5 -C 6 cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH 2 _ , —CH 2 (CH ) 3 CH —, -CH (CH 2 ) 4 CH 2 —, -CH 2 CH 2 0CH 2 CH 2 -, -CH 2 CH(Me)CH 2 CH(Me)CH 2 -, and -CH 2 CH(Me)OCH(Me) CH 2 -; R 21 is C 1 -C 8 alkyl optionally substituted with R 51 ; C 2 -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C3-C5 cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)SR 53 ; C(=NR 55 )OR 53 ; C(=S)SR 53 ; C(=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is 0; NR 55 ; or a direct bond; R 22 is cyano; nitro; C^C^ alkylthio; ^-C^ alkylsulfinyl; C 1 -C 19 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; C 1 -C 19 alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)O; R 39 R 40 N; (C 1. -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -C 6 cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is 0 or S; Q is 0 or N-T- ; T is 0; NR 37 ; or a direct bond; is H; C 1 -C 8 alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)0R 28 ; or C(=0)NR 28 R 14 ; R 23 is 1-3 halogen; C 1 -C 1 alkoxy; C 1 -C 12 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; ^-Cg alkyl; C^C haloalkyl; Cx-Cg alkoxy; C 1 -C 6 haloalkoxy; C x -C 4 alkylsulfonyl; C 2 -C 6 alkoxyalkyl; C ! -C alkyl¬ thio; C 5 -C 6 cycloalkyl; C 5 -C 6 cycloalkyloxy; C 2 -C 6 alkenyl; C -C 6 haloalkenyl; C 2 -C 6 alkynyl; hydroxycarbonyl; C 2 -C alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is C 1 -C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is C 1 -C 8 alkyl optionally substituted with R 44 ; C 3 -C 6 alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C[=N(C 1 -C 4 alkyl) ]0R 53 ; C(=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C 1 -C 4 alkyl, trifluoromethyl, C ] _-C 4 alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; C 1 -C 18 alkoxy; allyloxy; C 1 -C 18 alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C 2 -C 5 alkoxy¬ carbonyl; R 32 is 1-3 halogen; or C 1 -C alkoxy; R 35 is cyano; nitro; C 1 -C 17 alkylthio; C^C^ alkylsulfinyl; Cx-C^ haloalkoxy; C 5 -Cg cycloalkyloxy; C 2 -C 17 haloalkenyl; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C 1 -C 17 alkylsulfonyl; C -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 8 C(=0)0; R 28 0C(=0)0; R 28 R 0 NC(=0)0; R 40 R 3 N; (C 1 -0 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 1 R 38 N+; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; C^C^ alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 -C 17 haloalkoxyalkoxy; R 37 is H; Cx-Cg alkyl; or phenyl optionally substituted with R 7 ; R 39 is C^-C^ alkyl; C 2 -C 19 alkylcarbonyl; C 2 -C 19 alkoxycarbonyl; (R 9 R 40 N)C=0; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; C^-C^ alkylthio; C^C^ alkylsulfinyl; C-L-C- -J haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; C^C^ alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 0C(=0)0; R 28 R 0 NC(=0)0; R 40 R 39 N; (C 1 -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; C^C^ alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -Cg cycloalkyl; R 42 is cyano; nitro; C x -C 17 alkylthio; C -C - 7 alkylsulfinyl; C 1 -C 17 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C 1 _C 17 alkylsulfonyl; C -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 0C(=0)0; 0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra¬ hydropyranyl; 2-tetrahydropyranyloxy; C^C^ alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; C^C alkoxy; C -Cg haloalkoxy; C 2 -C 6 alkoxyalkoxy; C^C alkylthio; Cx-Cg alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 49 R 50 ; or R 62 ; R 45 is H; C ! -C 4 alkyl; C^^ haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 54 R 55 ; or SR 54 ; R 46 is H; C x -C 4 alkyl; C^d haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is C 1 -C 8 alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -Cg alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C[=N(C 1 -C 4 alkyl) ]0R 53 ; or C(=0)NR 53 R 56 ; R 48 is C -C alkyl; C 2 -C 6 alkenyl; C 2 -C 6 halo¬ alkenyl; C 2 -Cg alkynyl; C -Cg alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; CIL-C.4 alkyl; C 3 -C 4 alkenyl; or cyclo- propyl; R 50 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH 2 ) 4 -; -(CH 2 ) 5 - or -CH 2 CH 2 0CH 2 CH 2 -; R 51 is 1-3 halogen; C^C alkoxy; C 2 -C 6 haloalkoxy; C -Cg alkoxyalkoxy; C -Cg alkylthio; C- L -C haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyloxy; C^C alkylsulfonyl; C x -Cg haloalkylsulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; C 1 -C 4 alkyl; C_-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -Cg haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci-Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or C 1 -C alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; 0CF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or C 1 -C 4 alkyl; R 60 is C 1 -C 4 alkyl; C χ -C 4 haloalkyl; C 2 -C 4 alkenyl; C -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; C 1 -C 4 alkyl; Cτ_-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 62 is C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; C(=NR 55 )OR 53 ; C(=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC(=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC(=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N(R 56 )C(=0)OR 53 ; or N (R 56 ) C(=NR 55 )NR 53 R 54 ; R 63 is H; C -Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C -Cg alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is C- L -C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently C 1 -C alkyl; C 3 -C 4 haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; C 1 -C 4 alkyl; ^-, 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; C^C ή alkyl; C^- -Z^ haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)0R 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20. DETAILED DESCRIPTION OF THE INVENTION In the above recitations, the term "alkyl", used either alone or in compound words such as "alkylthio" or "haloalkyl" denotes straight-chain or branched alkyl; e.g., methyl, ethyl, n-propyl, i-propyl, or the different butyl, pentyl or hexyl isomers. "Alkenyl" denotes straight-chain or branched alkenes; e.g., 1-propenyl, 2-propenyl, 3-propenyl and the different butenyl, pentenyl and hexenyl isomers. "Alkenyl" also denotes polyenes such as 1,3-hexadiene and 2,4, 6-heptatriene. "Alkenyloxy" denotes straight-chain or branched alkenyloxy moieties. Examples of alkenyloxy include H 2 C=CHCH 2 0, (CH 3 ) 2 C=CHCH 2 0, (CH 3 )CH=CHCH 2 0, (CH 3 )CH=C(CH 3 )CH 2 0 and CH 2 =CHCH 2 CH 2 0. "Alkynyl" denotes straight-chain or branched alkynes; e.g., ethynyl, 1-propynyl, 3-propynyl and the different butynyl, pentynyl and hexynyl isomers. "Alkynyl" can also denote moieties comprised of multiple triple bonds; e.g., 2, 7-octadiyne and 2,5, 8-decatriyne. "Alkynyloxy" denotes straight-chain or branched alkynyloxy moieties. Examples include HCsCCH 2 0, CH 3 C≡CCH 2 0 and CH 3 CsCCH 2 CH 2 0. "Alkylthio" denotes branched or straight-chain alkylthio moieties; e.g., methylthio, ethylthio, and the different propylthio, butylthio, pentylthio and hexylthio isomers. Examples of "alkylsulfonyl" include CH 3 S0 2 , CH 3 CH 2 S0 2 , CH 3 CH 2 CH 2 S0 2 , (CH 3 ) 2 CHS0 2 and the different butylsulfonyl, pentylsulfonyl and hexylsulfonyl isomers. "Alkylsulfinyl" denotes both enantiomers of an alkylsulfinyl group. For example, CH 3 S0, CH 3 CH 2 S0, CH 3 CH 2 CH 2 SO, (CH 3 ) 2 CHS0 and the different butylsulfinyl, pentylsulfinyl and hexylsufinyl isomers. "Alkoxy" denotes, for example, methoxy, ethoxy, n-ρropyloxy, isopropyloxy and the different butoxy, pentoxy and hexyloxy isomers . Examples of "alkoxyalkoxyalkoxy" include CH 3 OCH 2 CH 2 OCH 2 0, CH 3 CH 2 OCH 2 CH 2 OCH 2 0, and (CH 3 ) 2 CHOCH 2 CH 2 OCH 2 0. "Cycloalkyl" denotes, for example, cyclopropyl, cyclobutyl, cyclopentyl, and cyclohexyl. The term "cyclqalkyloxy" denotes the same groups linked through an oxygen atom such as cyclopentyloxy and cyclo- hexyloxy. "Cycloalkenyl" denotes groups such as cyclopentenyl and cyclohexenyl. Examples of "cycloalkylalkyl" include cyclopropyl¬ methyl, cyclohexylethyl, and other cycloalkyl moieties bonded to straight-chain or branched alkyl groups. "Alkylcycloalkyl" denotes alkyl substitution on a cycloalkyl moiety. Examples include 4-methylcyclohexyl and 3-isopropylcyclopentyl. The term "halogen", either alone or in compound words such as "haloalkyl", denotes fluorine, chlorine, bromine or iodine. Further, when used in compound words such as "haloalkyl", said alkyl may be partially or fully substituted with halogen atoms which may be the same or different. Examples of "haloalkyl" include F 3 C, C1CH 2 , CF 3 CH 2 and CF 3 CF 2 . Examples of "haloalkenyl" include (C1) 2 C=CHCH 2 and CF 3 CH 2 CH=CHCH 2 . Examples of "haloalkynyl" include HC≡CCHCl, CF 3 C≡C, CC1 3 G≡C and FCH 2 C≡CCH 2 . Examples of "haloalkoxy" include CF 3 0, CC1 3 CH 2 0, CF 2 HCH 2 CH 2 0 and CF 3 CH 2 0. Examples of "haloalkylthio" include CC1 3 S, CF 3 S, CC1 3 CH 2 S and CH 2 C1CH 2 CH 2 S. Examples of "haloalkyl- sulfonyl" include CF 3 S0 2 , CC1 3 S0 2 , CF 3 CH 2 S0 2 and CF 3 CF 2 S0 2 . Examples of "haloalkoxyalkoxy" include CF 3 0CH 2 0, C1CH 2 CH 2 0CH 2 CH 2 0, C1 3 CH 2 0CH 2 0 as well as branched alkyl derivatives. The total number of carbon atoms in a substituent group is indicated by the "Ci-C j " prefix where i and j are numbers from 1 to 20. For example, C x -C 3 alkyl¬ sulfonyl designates methylsulfonyl through propyl- sulfonyl; C alkoxyalkoxy designates CH 3 0CH 2 0; C 3 alkoxyalkoxy designates, for example, CH 3 0CH 2 CH 2 0 or CH 3 CH 0CH 2 0; and C alkoxyalkoxy designates the various isomers of an alkoxy group substituted with a second alkoxy group containing a total of 4 carbon atoms, examples including CH 3 CH 2 CH 2 OCH 2 0, and CH 3 CH 2 0CH 2 CH 2 0. Examples of "alkoxyalkyl" include CH 3 0CH 2 , CH 3 OCH 2 CH 2 , CH 3 CH 2 OCH 2 , CH 3 CH 2 CH 2 CH 2 OCH 2 and CH 3 CH 2 OCH 2 CH 2 . Examples of "alkoxycarbonyl" include CH 3 0C(=0), CH 3 CH 2 OC(=0) , CH 3 CH 2 CH 2 0C(=0) , (CH 3 ) 2 CH0C(=0) and the different butoxy-, pentoxy- or hexyloxycarbonyl isomers. In the above recitations, when a compound of Formula I is comprised of one or more pyridyl or pyrimidinyl rings, all bonds to these heterocycles are made through the carbon atom(s) of the moieties. When a substituent for a compound of Formula I is defined to include 1-2 halogen or 1-3 halogen, this denotes the occurrence of the same or different halogens at that substituent position one, two, or three times. When R 1 and R 2 of the compounds of Formula I are different, then the compounds of Formula I possess a chiral center. This invention, therefore, comprises racemic mixtures as well as pure enantiomers. Compounds of Formula I can also exist as (E) - or (Z) -isomers, or as a mixture of (E)- and (Z) -isomers when compounds of Formula I contain a C=C bond or a C=N bond. This invention, therefore, also comprises mixtures of geometric isomers as well as the individual isomers. Preferred compounds of Formula I (denoted as Preferred 1) are those wherein: R 1 is C 1 -C 4 alkyl; ^-- 4 haloalkyl; C 3 -C 4 cycloalkyl; or C -C 4 alkenyl; R 21 is C ! -C 4 alkyl optionally substituted with R 51 ; C 2 -C 4 alkenyl, C 2 -C 8 alkynyl, or cyclopropyl each optionally substituted with 1-3 halogen; C(=N-V-R 53 )H; C(=N-V-R 53 ) (Ci-C ή alkyl); C(=0)0R 53 ; C(=0)SR 53 ; C(=S)SR 53 ; or C(=0)NR 53 R 56 ; R 29 is Ci-C alkyl optionally substituted with R 44 ; C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, or cyclopropyl each optionally substituted with 1-3 halogen; C (=0) R 52 ; C (=NR 55 ) R 52 ; C (=0) OR 53 ; C (=0) NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 44 is 1-3 halogen; cyano; nitro; C 1 -C alkoxy; C 1 -C 4 haloalkoxy; C 2 -C 4 alkoxyalkoxy; C_-C 4 alkylthio; or R 62 ; R 45 is H; C 1 -C 4 alkyl; C x -C 4 haloalkyl; C 2 -C 4 alkenyl; or C -C 4 haloalkenyl; R 46 is H; C j _-C 4 alkyl; C 1 -C haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is Cx-C, } alkyl optionally substituted with R 44 ; C 3 -C alkenyl or C 3 -C alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; C(=0)R 52 ; C(=0)0R 53 ; or C(=0)NR 53 R 56 ; R 48 is C 1 -C alkyl; C 2 -C 4 alkenyl; C 2 -C haloalkenyl; C 2 -C 4 alkynyl; or C 2 -C 6 alkoxy¬ alkyl; R 49 is H; C ! -C 4 alkyl; C 3 -C 4 alkenyl; or cyclo¬ propyl; R 50 is H; C 1 -C 4 alkyl; C 3 -C alkenyl; or C 3 -C alkynyl; or R 49 and R 50 can be taken together to form -(CH 2 ) -; -(CH 2 ) 5 - or -CH 2 CH 2 0CH 2 CH 2 -; R 51 is 1-3 halogen; CX-C 4 alkoxy; C -C 4 haloalkoxy; C -C 4 alkoxyalkoxy; C- L -C 4 alkylthio; C 3 -C 4 alkenyloxy; C 3 -C 4 alkynyloxy; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; C χ -C alkyl; C 1 -C 4 haloalkyl; C 2 -C alkenyl; or C 2 -C 4 haloalkenyl; R 53 is H; C x -C 4 alkyl; C 3 -C 4 alkenyl; or C 3 -C 4 haloalkenyl; R 60 is Ci-C 4 alkyl; C 1 -C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 4 haloalkenyl; C(=0) (C 1 -C 4 alkyl); or C(=0)H; R62 i s C (=N-V-R 53 ) R 52 ; C (=0) OR 53 ; C (=0) NR 53 R 56 ; 0C (=0) R 52 ; SC (=0) R 52 ; N (R 56 ) C (=0) R 52 ; 0C (=0) 0R 53 ; 0C (=0) NR 53 R 56 ; or N (R 56 ) C (=0) OR 53 ; R 63 is H; C 1 -C 4 alkyl; C 3 -C 4 alkenyl; C 3 -C 4 alkynyl; C 3 -C 4 haloalkenyl; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C(=0)NR 53 R 56 ; or OR 53 ; R 64 is C ! -C alkyl; or C 3 -C alkenyl; R 65 is C 1 -C 4 alkyl; C 3 -C 4 haloalkyl; or C 3 -C 4 alkenyl; and R 67 is H or Ci-C 4 alkyl; provided that when R 3 is a phenyl or heterocyclic ring disubstituted with two alkyl or alkoxy groups, or one alkyl and one alkoxy group, then at least one of the alkyl and alkoxy groups is methyl or methoxy. More preferred compounds of Formula I (denoted as Preferred 2) are the compounds of Preferred 1 wherein: A is 0 or NH; B is halogen; cyano; R 21 ; OR 29 ; NR 49 R 63 ; N=CR 45 R 46 ; SR 47 ; or S(0) 2 R 48 ; R 1 is C x -C4 alkyl; C 2 .-C 4 haloalkyl; or vinyl; R 2 is C 2 -C 20 alkyl; C 2 -C 20 alkoxyalkyl; C 2 -C 0 haloalkyl; C 3 -C 8 alkyl substituted with phenoxy or phenylthio each optionally substituted with R 30 ; C 5 -C 7 cycloalkyl; C 2 _C 20 alkenyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; provided that when R 2 is phenyl and R 5 is other than F, then R 5 is attached to the para- position relative to the imidazolinone ring; R 3 is phenyl optionally substituted with R 10 ; R 44 is 1-3 halogen; C J. -C 4 alkoxy or C^-C^; haloalkoxy; R 45 is H or Ci-C 4 alkyl; R 46 is H; C 1 -C 4 alkyl; OR 65 ; or SR 65 ; R 47 is C- L -C ή alkyl; C 3 -C 4 alkenyl; C(=0)R 52 ; or C(=0)0R 55 ; R 48 is C 1 -C 4 alkyl; R 51 is 1-3 halogen or C 2 -C 3 haloalkoxy; R 52 and R 53 are each independently H; Cι~C 4 alkyl; or C 3 -C alkenyl; R 60 and R 63 are each independently Ci-C 4 alkyl; and R 65 is C--C 4 alkyl or C 3 -C 4 alkenyl. More preferred compounds of Formula I (denoted as Preferred 3) are the compounds of Preferred 2 wherein: B is halogen; cyano; C -C. 4 alkyl, C 1 -C alkylthio, or Ci-C 4 alkoxy each optionally substituted with halogen; N=CR 45 R 46 ; NR 49 R 63 ; or S(0) 2 (C 1 -C 4 alkyl) ; R 1 is methyl or halomethyl; R 2 is C 2 -C 12 alkyl; C 3 -C 8 alkyl substituted with phenoxy optionally substituted with R 30 ; phenyl optionally substituted with R 5 and R 7 ' thienyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; R 3 is phenyl optionally substituted with F; Cl; or methyl; R 4 is H; R 5 is halogen; nitro; Ci-Cg alkyl; Ci-C 3 haloalkyl; methylthio; C j^ -C alkoxy; Ci-C 2 haloalkoxy; C 5 -C 6 cycloalkyloxy; phenoxy optionally substituted with R 27 ; phenylthio substituted with R 24 ; phenoxymethyl optionally substituted with R 24 on the phenyl ring; benzyloxy optionally substituted with R 30 on the phenyl ring; or -OC(=0)R 28 ; R 7 and R 24 are independently F; C_-C 2 alkyl; methyl¬ thio; or C 1 -C 2 alkoxy; R 1 , 6 is Ci-Cg alkyl; R 19 is phenyl optionally substituted with R 34 ; R 27 is 1-2 halogen; cyano; 0 2 -0 4 alkyl; trifluoro¬ methyl; C x -C alkoxy; C 1 -C haloalkoxy; C x -C 4 alkylthio; C 5 -C 6 cycloalkyloxy; or allyl; R 30 is 1-2 halogen; cyano; C x -C alkyl; trifluoro¬ methyl; C x -C alkoxy; or trifluoromethoxy; R 34 is 1-2 halogen; nitro; C x -C alkyl; or C 1 -C alkoxy; R 46 is H or C- L -C 4 alkyl; R 49 and R 63 are each independently ~ χ- ~ 2 alkyl. Especially preferred compounds of Formula I (denoted as Preferred 4) are the compounds of Preferred 3 wherein: B is F; Cl; cyano; C 3. -C 2 alkyl; C 1 -C 2 alkylthio; C -C- 2 alkoxy; N=CR 45 R 46 ; NMe 2 ; or S(0) 2 (C 1 -C 2 alkyl) ; R 1 is methyl; R 2 is C 1 -C 12 alkyl; phenyl optionally substituted with R 5 and R 7 ; or thienyl optionally substituted with R 5 and R 7 ; and R 5 is F; Cl; Br; C^-Cg alkyl; trifluoromethyl; C-^C alkoxy; trifluoromethoxy; 2, 2, 2-trifluoro- ethoxy; C 5 -Cg cycloalkyloxy; methylthio; phenoxy optionally substituted with R 27 ; phenylthio optionally substituted with R 24 ; benzyloxy optionally substituted with R 30 on the phenyl ring; or -OC(=0)R 28 . Specifically preferred compounds of Formula I are the compounds of Preferred 4 which are: 3, 5-dihydro-2-methoxy-5-methyl-5-phenyl-3- (phenylamino) -4H-imidazol-4-one; and 3, 5-dihydro-5-methyl-2- (methylthio) -5-phenyl-3- (phenylamino) -4H-imidazol-4-one. It is recognized that some reagents and reaction conditions described below for preparing compounds of Formula I may not be compatible with some functionalities claimed for R 1 , R 2 , R 3 , R 4 , A and B. In these cases, the incorporation of protection/ deprotection sequences into the synthesis may be necessary in order to obtain the desired products. The cases in which protecting groups are necessary, and which protecting group to use, will be apparent to one skilled in chemical synthesis. In the following description of the preparation of compounds of Formula I, compounds denoted as Formula la through Formula Ix are various subsets of the compounds of Formula I, and all substituents for Formula la through Ix are as defined above for Formula I. The compounds of Formula I can be prepared as described below in the following Schemes . The (H) -imidazol-4-ones of Formula la can be prepared by one or all of the methods illustrated in Scheme I. SCHEME I Method I NH-N- »r3R_4 la Z=C 1 -C 4 alkyl, C 3 ~C 4 alkenyl, C 3 -C 8 cycloalkyl, CgH 5 CH 2 X=C1, Br, I Method II la Method III The esters of α-amino-acids of Formula 1 or their salts are known in the literature and can be prepared by literature methods [J. P. Greenstein, M. Winitz, "Chemistry of the Amino Acids" (S. Patai, Ed.), p 697, John Wiley and Sons, Ltd., London (1961)] . The group Z in compounds of Formula 1 can be C j^ -C ^j alkyl; C 3 -C alkenyl; C 3 -C 6 cycloalkyl; or C 6 H 5 CH 2 . Preferred for ease of synthesis and lower expense are Z=C 1 -C 4 alkyl. The preparation of the isothiocyanates of Formula 2 from the α-amino esters or their salts of Formula 1 (Step 1) can also be accomplished by literature methods (H. A. Staab and G. Walther, Liebigs Ann . Chem . . 1962, 557, 98; M. L. Moore, F. S. Crossley, Org. Synth . , 1941, 21 , 81) . Compounds of Formula 4 can be prepared by treatment of an isothiocyanates of Formula 2 with hydrazines of Formula 3 (Step 2) . The preparation of substituted hydrazines of Formula 3 can be accomplished by literature methods (J. Timerblake, J. Stowell; "The Chemistry of the Hydrazo, Azo and Azoxy Groups" (S. Patai, Ed.) p 69, John Wiley and Sons, Ltd., London (1975); J. P. Demers, D. J. Klaubert, Tetrahedron Lett . , 1987, 4933) . To prepare compounds of Formula 4, the compounds of Formula 2 are dissolved in an inert solvent such as 1-chlorobutane or dichloromethane, and a hydrazine of Formula 3 is added, at a temperature from -50° to 50°C. When the reaction is complete, the resulting mixture is poured into a water-immiscible solvent and washed successively with dilute aqueous mineral acid, water, and brine. The organic phase of this mixture is separated, dried, and the solvent is evaporated to provide the products of Formula . As shown in Step 3, the 2-thioxo-4-imidazolidinone compounds of Formula 5 can be prepared by dissolving compounds of Formula 4 in an inert solvent, such as benzene or toluene, and heating at a temperature from 50° to 200°C. When the reaction is complete, the solvent is evaporated and the resulting mixture is purified to yield products of Formula 5. In some cases, the isolation of compounds of Formula 4 is unnecessary. For example, compounds of Formula 4 can be converted in situ to compounds of Formula 5 by warming the reaction mixture to 50°-200°C. When the reaction is complete, the solvent is removed to provide compounds of Formula 5. The 4 (H) -imidazol-4-ones of Formula la can be prepared by dissolving compounds of Formula 5 in an inert solvent, such as chloroform or tetrahydrofuran, and treating the solution with an electrophilic substrate R 47 X wherein X is a leaving group such as a chlorine, bromine, or iodine; followed by a base such as 1, 8-diaza-bicyclo[5.4.0] -undec-7-ene, at a temperature from 0° to 100°C (Step 4) . When the reaction is complete, the solvent is evaporated and the resulting mixture is purified to yield products of Formula la. An alternative process for preparing compounds of Formula la is illustrated in Method II, Scheme I. The α-bis (thio)methyleneamino acid esters of Formula 7 can be prepared by literature methods (D. Hoppe, Angew. Chem . - Int . Ed . Eng . , 1975, 14, 426) . Compounds of Formula la can be prepared by dissolving compounds of Formula 7 in a protic acid, such as acetic acid, with or without an inert diluent, such as dichloromethane, in the presence of a hydrazine of Formula 3, at a temperature from 20° to 100°C. When the reaction is complete, the reaction mixture is poured into water and extracted with a water-immiscible organic solvent such as ethyl acetate. The combined organic extracts are washed first with aqueous base, such as aqueous sodium bicarbonate, and then with water. The organic layer is then dried and evaporated to yield compounds of Formula la. Another route to synthesize compounds of Formula la is illustrated in Method III, Scheme I. This method is described in the literature for when R 1 is H and neither R 3 nor R 4 are H (H. Boehme, F. Martin, J. Strahl; Arch . Pharm . 1980, 313, 10) . As shown in Step 1, a α-chlorohydrazide, prepared by literature methods (H. Bδhme, F. Martin, Aca . Pharm . , 1974, 307, 277), is treated with a salt of a thiocyanate, such as potassium thiocyanate, in an inert solvent, such as acetonitrile at a temperature from 0° to 50°C. When the reaction is complete, the reaction mixture is poured into water and extracted with a water-immiscible solvent such as chloroform. The organic extracts are combined and washed with water. The solvent is removed to give a residue which is redissolved and refluxed in an inert organic solvent such as acetonitrile. When the reaction is complete, the solvent is removed and the resulting mixture is purified to give a compound of Formula 5. The conversion of compounds of Formula 5 to compounds of Formula la is described in Step 4 , Method I . SCHEME II Ifi l SCHEME III Z=C 1 -C 4 alkyl, C 3 ~C 4 alkenyl, C 3 ~Cg cycloalkyl, PhCH 2 The sulfoxides and sulfones of Formula Ic and Id, respectively, can be prepared by the methods illustrated in Scheme II. The oxidation of sulfides to sulfoxides and sulfones is described in the literature (D. S. Tarbell, C. Weaver, J. Am . Chem . Soc , 1941, 63, 2939; I. Sircar et al., J. Med. Chem . , 1985, 28, 1405). Compounds of Formula lb are dissolved in an inert solvent such as dichloromethane or benzene and an oxidant such as meta-chloroperoxybenzoic acid or mono- perphthalic acid is added (Step 1) . The reaction can be conducted at a temperature from 0° to 100°C. When the reaction is complete, the reaction mixture is added to a water-immiscible solvent, washed sequentially with aqueous sodium thiosulfate solution, aqueous sodium bicarbonate solution, and water. The organic layer is dried and the solvent is evaporated to yield compounds of Formula Ic. Following the same procedure, the preparation of sulfones of Formula Id can can be achieved either from sulfoxides of Formula Ic (Step 2), or from compounds of Formula lb with the use of excess oxidant (Step 3) . Compounds of Formula le can be obtained as described in Scheme III. The oxidation of sulfides to the corresponding sulfonyl chlorides (Step 1) and reaction of the sulfonyl chlorides with an amine (Step 2) provides the sulfonamides. For example, to a solution of the sulfide compounds in a solvent such as acetic acid containing a small amount of water, a source of chlorine, such as chlorine gas is added, at a temperature from 0° to 50°C. When the reaction is complete, the sulfonyl chloride is collected, stirred in an inert solvent such as acetone, at a temperature from -10° to 25°C, and an amine of Formula 10 is added. When the reaction is complete, the solvent is removed to provide compounds of Formula le after purification. This sequence is well documented in the literature (R. H. Baker et al., J " . Am. Chem . Soc, 1946, 68, 2636; R. F. Langler, Can . J. Chem . , 1976, 54, 498; J. S. Grossert, R. F. Langler, Can . J. Chem . , 1977, 55, 407, 421) . The amines of Formula 10 can be prepared by literature methods [C. A. Buehler, D. E. Pearson, Survey of Organic Syntheses, Vol. 2, p 391, John Wiley and Sons (1977) ] . SCHEME IV Method I 11 12 11 ιa , 0 is R 21 or H Z is C--C 4 alkyl; C 3 ~C 4 alkenyl; C 3 -Cg cycloalkyl; P CH 2 Method II 14. If Y is alkyl Method III I ~ The 4H-imidazol-4-one compounds of Formula If can be prepared by one or more of the methods shown in Scheme IV. The preparation of compounds of Formula 11 from the amino acids of Formula 1 or their salts (Step 1, Method I) can be accomplished using known procedures in the literature [C. A. Buehler, D. E. Pearson, Survey of Organic Syntheses, Vol. 2, p 813, John Wiley and Sons (1977); V. Prelog, P. Wieland, Helv. Chim . Acta, 1946, 29, 1128]. The preparation of the iminochlorides of Formula 12 (Step 2) from the amides of Formula 11 can be accomplished by literature methods (J. W. Williams et al., Org. Synth . , 1946, 26, 97; C. C. Price, B. H. Velzar, J. Org. Chem . , 1947, 12, 386). The displacement of the chloride in the iminochlorides with the hydrazines of Formula 3 (Step 3) can also be achieved by procedures known in the literature (H. Priewe, A. Polzak, Ber. Deutsch . Chem . Ges ., 1955, 88, 1932; J. Berger et al., Monatsch . Chem . , 1981, 112, 959) . The cyclization of compounds of Formula 13 to heterocycles of Formula If (Step 4) can be accomplished by literature procedures known for the cyclization of N-(aminomethylidene)-α-amino acids to 4H-imidazolin-4- ones (Y. Ito et al., Synth . Commun . , 1974, 4, 289; J. R. Ross et al., J. Heterocycl . Chem . , 1987, 24, 661) . Alternatively, the compounds of Formula If can be prepared by the procedure illustrated in Method II, Scheme IV. The hydrazides of Formula 14 can be prepared by procedures known in the literature (M. Brenner, W. Hofer, Helv. Chim . Acta, 1961, 44, 1798; Unit Ika KK, JP 246,362). The condensation of compounds of Formula 14 with ortho-esters of Formula 15 provides compounds of Formula If. For example, an amino-hydrazide of Formula 14 is mixed with an ortho- ester of Formula 15, in the presence of a catalytic amount of acid, such as acetic acid, at a temperature from 50° to 200°C. When the reaction is complete, the mixture is purified to provide the product of Formula If. The following literature procedures describe the preparation of 4H-imidazol-4-ones from α-amino carboxylic acid amides and ortho-esters (S. Ginsburg, J. Org. Chem . , 1962, 21, 4062; J. Brunken, G. Bach, Ber. Deutsch . Chem . Ges ., 1956, 89, 1363) . The ortho-esters of Formula 15 can be prepared according to processes described in the literature [C. A. Buehler and D. E. Pearson, Survey of Organic Syntheses, Vol. 2, p 711, John Wiley and Sons (1977)] . In addition, a method to prepare the compounds of Formula lg is shown in Method III, Scheme IV. The 2-thioxo-4-imidazolidinone of Formula 5 is dissolved in an inert solvent such as acetone and an oxidizing agent such as Oxone ® (potassium peroxymonosulfate) is added at a temperature from 0°-100°C. When the reaction is complete, the reaction mixture is poured into a water- immiscible organic solvent such as ethyl acetate and washed with a basic aqueous solution, such as aqueous sodium bicarbonate, and then with water. The organic layer is dried and the solvent is evaporated to give the products of Formula lg. SCHEME V Method I Ifi 12 Z=C 1 -C 4 alkyl, C 3 ~C alkenyl, C 3 ~C cycloalkyl, C H 5 CH 2 lh hal=halogen Method II 1A 12 Ih hal-halogen Method III lh The compounds of Formula lh can be prepared by one or more of the methods illustrated in Scheme V. The isocyanates of Formula 16 can be prepared (Step 1, Method I) by literature methods, using reagents such as phosgene (L. C. Raitord, H. B. Freyermuth, J. Org. Chem., 1943, 8, 230; G. Losse, W. Godicke, Ber. Deυtsch. Chem. Ges . , 1967, 100, 3314), N- N' -carbonyldiimidazole (H. A. Staab, W. Benz, Angew. Chem . , 1961, 13, 66), or oxalyl chloride (V. Von Gizycki, Angew. Chem . , 1971, 83, 406; M. W. Gittos et al., J. Chem . Soc , Perkin Trans . 1, 1976, 141) . The compounds of Formula 17 can be prepared by mixing the isocyanates of Formula 16 and hydrazines of Formula 3 in an inert solvent such as chlorobutane or tetrahydrofuran at a temperature of 0° to 50°C (Step 2) . When the reaction is complete, the reaction mixture is poured into an organic solvent and washed sequentially with a dilute aqueous mineral acid solution, a dilute aqueous basic solution, and water. The organic fraction is dried and the solvent is evaporated to give a residue which is redissolved in an inert solvent such as toluene and heated at a temperature of 60° to 200°C. When the cyclization is complete, the solvent is removed to provide compounds of Formula 17. The preparation of 4 (H)-imidazol-4-ones of Formula lh from compounds of Formula 17 (Step 3) can be accomplished using literature procedures known to convert ΝHC(=0) groups to N=C(halogen) groups (D. Harrison et al., J. Chem . Soc , 1963, 2930; R. Appel et al., Ber. Deutsch . Chem . Ges . , 1974, 107, 698; H. V. Dobeneck, T. Messerschmitt, Liebigs Ann . Chem . , 1971, 151, 32; G. Rio, D. Masure, Bull. Soc. Chim . Fr . , 1972, 4604). Compounds of Formula 17 can also be prepared from compounds of Formula 14 (Method II, Scheme V) using procedures known in the literature for the preparation of hydantoins from α-amino carboxylic acid amides (S. Goldschmidt, M. Wick, Liebigs Ann . Chem . , 1952, 515, 217) . Conversion of hydantoins of Formula 17 to heterocycles of Formula lh is discussed in Step 3 above. Another method to prepare compounds of Formula lh is illustrated in Method III, Scheme V. This conversion can be accomplished using literature procedures (C. R. Petrie et al., J. Med. Chem . r 1985, 28, 1010; R. E. Holmes, R. K. Robins, J " . Am. Chem . Soc , 1964, 86, 1242; R. T. Koda, J. A. Biles, W. Wolf, J. Pharm . Sci . , 1968, 51, 2056) known for the conversion of NHC(=S) groups to the corresponding N=C(halogen) groups. SCHEME VI 18. li ϋ=Cl, Br, I, SZ or S(0) 2 Z alkyl, C 3 -_ 4 alkenyl, C 3 -Cg cycloalkyl, CgH 5 _H_ The cyano compounds of Formula li can be prepared according to literature procedures for the conversion of -N=C-U functionalities, wherein ϋ=Cl, Br, I, SZ, S(0) 2 Z and Z is defined as described above, to -N=C-C≡N moieties, by displacing the group U with cyanide salts. For example, a sulfonyl compound of Formula 18 (Q=S(0) 2 Z) is treated with a salt of cyanide, such as potassium cyanide, in an inert solvent, such as dimethysulfoxide, at a temperature from 20° to 200°C. When the reaction is complete, the reaction mixture is poured into water and extracted with an organic solvent. The organic extracts are combined, and washed with water. The solvent is removed to provide a product of Formula li after purification. (Scheme VI, N. G. Clark, E. Cawkill, Tetrahedron Lett . , 1975, 2717; T. Kato et al., Chem . Pharm . Bull . . 1986, 34, 3635; P. A. Wade et al., J. Org. Chem . , 1983, 48, 1796) SCHEME VII m SCHEME VIII U_ U_ Compounds of Formulae Ij and Ik can be prepared as illustrated in Schemes VII and VIII, respectively. Compounds of Formula Ij can be prepared by displacement of leaving group U with sources of isocyanate, such as the sodium or potassium salt of isocyanate. For example, to a salt of isocyanate, such as potassium isocyanate, in an inert solvent, such as dichloromethane, at a temperature of 20° to 150°C, a compound of Formula 18 is added, with or without the use of a catalytic amount of crown ether, such as 18-crown-6 ether, or a phase transfer reagent, such as tetra-n-butylammonium iodide. When the reaction is complete, the solvent is removed and the residue is purified to yield an isocyanate of Formula Ij. (J. Geordeler, ' R. Richter, Synthesis, 1978, 760) Similarly, the isothiocyanate compounds of Formula Ik can be prepared by displacement of the leaving group U with sources of isothiocyanate such as the ammonium or mercuric salts of isothiocyanate. For example, to a stirred solution of a salt of thio¬ cyanate, such as mercuric thiocyanate, in an inert solvent, such as carbon tetrachloride, at a temperature of 0° to 100°C, a compound of Formula 18 is added. When the reaction is complete, the reaction mixture is filtered and solvent is removed to provide, after purification, a compound of Formula Ik. See, for example, G. Barnikow, W. Abraham, Z . Chem . , 1970, 10, 193; J. Goerdeler et al., Ber. Deutsch . Chem . Ges . , 1975, 108, 3071; G. Barnikow et al., Z . Chem . , 1980, 20, 55. SCHEME IX Method I 12 II Method II u_ II II Z = c ι -c 4 alkyl ; C 3 ~C 4 alkenyl; C 3 -Cg cycloalkyl; PhCH 2 As illustrated in Method I, Scheme IX, 4 (H)-imidazol-4-ones of Formula II can be prepared by reaction of compounds of Formula 17 with reactive electrophiles such as alkyl sulfates (R. Menezes, M. B. Smith, Synth . Commun ., 1988, 18, 1625; G. H. Rasmusson et al., J. Med . Chem . , 1984, 21, 1690); alkyl halides (D. Libermann et al., C. R. Acad. Sci . , 1953, 237, 338; S. K. Sihka et al., Indian J. Chem . B, 1985, 24, 1035; G. Klein et al., Helv. Chim . Acta, 1955, 38, 1412); alkyl sulfonates (W. Ried, E. Schmidt, Liebigs Ann . Chem . , 1965, 616, 114, J. A. Warshaw et al., J. Org. Chem . , 1989, 54, 1736); activated carbonyl compounds, such as carboxylic acid halides (R. R. Koganty, G A. Digenis, J. Labelled Compounds, 1974, 10, 419; M. Miyake et al., Synth . Commun . , 1984, 14, 353), isocyanates (W. Logel, K-H. Pook, Chem . Rev. , 1986, 119, 2553); or diazoalkanes (H. Nishiyama et al., Tetrahedron Lett . , 1979, 4671) . In addition, compounds of Formula II can be prepared as illustrated in Method II, Scheme IX by displacing the group U in compounds of Formula 18 with nucleophiles. For example, to a stirred solution of a salt of an alcohol, such as sodium ethoxide, in the corresponding alcohol, in this case, ethanol, or in an inert solvent, such as dimethylformamide, a compound of Formula 18 is added. The reaction is carried out at a temperture of 20° to 200°C. When the reaction is complete, the solvent is removed and the residue purified to provide a compound of Formula II. (E. C. Tayler, F. Koenzle, J. Org. Chem . , 1971, 36, 233; S. E. Forman et al., J. Org. Chem . , 1963, 28, 2653; P. A. Wade et al., J. Org. Chem . , 1983, 48, 1796; M. Mori, Synthesis, 1987, 278) . In addition, compounds of Formula II can be prepared by the methods illustrated in Method III, Scheme IX. The isocyanates of Formula 2 can be condensed with alcohols of Formula HOR 29 using literature procedures to form the corresponding thionocarbamates (E. Campaign, P. K. Nargund, J. Org. Chem . , 1964, 29, 224; G. S. Skinner, H. C. Vogt, J. Amer . Chem . Soc , 1955, 77, 5440). The thiono¬ carbamates can be alkylated as illustrated in Step 2 using known methods (R. Gompper, Ber. Deutsch . Chem . Ges . , 1956, 89, 762; M. Kulka, Can . J. Chem . , 1982, 41, 1985) . Compounds of Formula II can be prepared from treatment of the alkylated thionocarbamate with hydrazines of Formula 3 as illustrated in Step 3. In some instances, the intermediate acyclic compound can be isolated and cyclized in a separate step. Example 3 below describes this synthetic sequence in detail. SCHEME X Method I ιa Iffi 12. In Method II li 2SL 21 Step 3 m Method III Ij Iffl The compounds of Formula Im can be prepared by one or more of the methods illustrated in Scheme X. One method of preparing compounds of Formula Im involves the displacement of group ϋ in compounds of Formula 18 with compounds containing a nitrogen bearing at least one hydrogen (Method I) such as ammonia and its salts (A. V. N. Reddy et al., Synthesis, 1986, 864; A. Yamazaki et al., J. Org. Chem . , 1967, 32, 3032, 3258; T. Ravindranathan et al., Org. Prep . Proced. Int . , 1986, 18, 95); primary amines of Formula 19 (M. J. S. Dewar, J. Chem . Soc , 1944, 534; L. Fishbein, J. A. Gallaghan, J. Am. Chem . Soc , 1954, 16, 1877); and secondary amines of Formula 19 (S. R. Aspinall, E. J. Bianco, J. Am . Chem . Soc , 1951, 73, 602; ibid., 1957, 19, 2199) . For example, to a stirred solution of a compound of Formula 18 in an inert solvent such as chloroform, at a temperature of 0° to 150°C, an amino compound of Formula 19 is added. When the reaction is complete, solvent is removed and the residue thus obtained is purified to give a compound of Formula Im. Compounds of Formula In (Method I) can be prepared in a similar manner by treating compounds of Formula 18 with hydroxylamines of the formula HN(R 4 )OR 53 or their salts. For example, to a stirred solution of a compound of Formula 18 in an inert solvent such as tetrahydrofuran, at a temperature of 0° to 100°C, a hydroxylamine or its salt is added, followed by a base, such as triethylamine. When the reaction is complete, the reaction mixture is poured into water and extracted with an organic solvent. The combined organic extracts are washed with water and the solvent is removed to yield, after purification, a compound of Formula In. (L. H. Briggs et al., Aust . J. Chem . , 1976, 29, 357; R. A. Long et al., Biochim . Biophys . Acta, 1969, 195, 584) The primary and secondary amines of Formula 19 can be prepared by literature methods [C. A. Buehler, D. E. Pearson; Survey of Organic Synthesis, Vol. 9, p 391, John Wiley and Sons (1977)]. The hydroxylamines of the formula HN(R 49 )OR 53 or their salts can also be prepared by literature methods [S. Sandier, W. Karo, Org. Functional Group Preparation, Vol. Ill, p 322, Academic Press (1972)]. Alternatively, compounds of Formula Im can be prepared as illustrated in Method II, Scheme X. The compounds of Formula 21 can be prepared by one or both of the procedures shown. Compounds of Formula Ii (for the preparation of Ii, see Scheme VI) can be hydrolyzed (Step 1) by literature methods to amides of Formula 20 [C. A. Buehler, D. E. Pearson, Survey of Organic Synthesis, Vol. 2, 813, John Wiley and Sons (1977); H. O. Larson et al., J. Org. Chem . , 1969, 34, 525] which in turn can be converted (Step 2) to compounds of Formula 21 by methods described in the literature (R. C. Jones, J. Am. Chem . Soc , 1951, 73, 5610; J. Buchi et al., Helv. Chim . Acta, 1949, 32, 1806; F. J. McCarty et al., J. Med. Chem . , 1970, 13, 814). Another way to prepare compounds of Formula 21 is to hydrolyze (Step 3) compounds of Formula Ij using procedures known in the literature (J. Weinstock, J. Org . Chem . , 1961, 26, 3511; A. Hassner, C. Heathcock, Tetrahedron, 1964, 20, 1037) . Compounds of Formula Im can be f prepared from compounds of Formula 21 by derivatization of the amino group at the 2-position of the 4H-imidazol-4-ones of Formula 21 (Step 4) with reactions such as alkylations (A. M. Monro, Chem . Ind. , 1964, 1806; P. Nesbitt, P. Sykes, J. Chem . Soc , 1954, 3057; P. Molina et al., Chem . Ber. , 1988, 121, 1495), acylations (M. Van Montagu et al., Bull. Soc Chim . Belg. , 1968, 77, 171; M. S. Newman, V. Lee, J. Org. Chem . , 1975, 40, 381), sulfonylations (H. J. Barker, J. Chem . Soc , 1943, 101; N. T. Markiewicz et al., Nucleos . Nucleot . , 1987, 6, 769), carbamoylations (G. Schwenker, R. Kolb, Tetrahedron, 1969, 25, 5437; T. L. Hough et al., J. Heterocycl . Chem . , 1986, 23, 1125), reactions with imidoyl chlorides (F. Findeisen, Synthesis, 1972, 599; 0. Tsuge et al., J. Org. Chem . , 1974, 39, 1226) , reactions with alkyl chloroformates (W. Hunt, E. C. Wagner, J. Org. Chem . , 1951, 16, 1792; D. R. Shridhar et al., Indian J. Chem . , 1980, 19, 699; M. Meldal, J. W. Kindtler, Acta Chem . Scand. B, 1986, 40, 235); or a combination of these reactions. In addition, compounds of Formula Im, wherein R 63 is C(=0)OR 53 and C(=0)NR 53 R 56 , can be prepared by literature procedures from isocyanates of Formula Ij (see Scheme VII for the preparation of Ij) by treatment with alcohols (S. R. Sandier and W. Karo, Organic Functional Group Preparations, Vol. II, p 223, Academic Press, Inc. (1971)) or amines (S. R. Sandier and W. Karo, Organic Functional Group Preparations, Vol. II, p 135, Academic Press, Inc. (1971)), respectively. SCHEME XI Method I Method II 21 22 12 Method III The compounds of Formula lo can be prepared by one or more of the methods illustrated in Scheme XI. As shown in Method I, the compounds of Formula lo can be obtained from amino compounds of Formula 21 by condensation with carbonyl compounds of formula R 45 R 46 C=0 (H. Van Der Poel, G. Van Koten, Synth . Commun . , 1978, 8, 305; M. Chaykowsky et al., J. Heterocycl . Chem . , 1977, 14, 661), dialkyl acetals of amides of formula R 45 C(OMe) 2 NR 56 R 64 to form compounds of Formula lo wherein R 6 =NR 56 R 64 (J. J. Fitt, H. W. Gischwend, J. Org. Chem . , 1977, 42, 2639; J. Zemlicka et al., Collect . Czech, Chem . Commun . , 1966, 31, 2198) , or ortho-esters of carboxylic acids of formula R 45 C(OR 65 ) 3 to form compounds of Formula lo wherein R 6 =OR 65 . For example, an amino compound of Formula 21 is stirred with an ortho-ester, with or without the use of solvent, at a temperature of 30° to 200°C. When the reaction is complete, the reaction mixture is purified to provide a compound of Formula lo. (R. A. Crochet, Jr., C. D. Blanton, Jr., Synthesis, 1974, 55; F. M. F. Chen, N. L. Benoiton, Can . J. Chem . , 1977, 55, 1433). The carbonyl compounds, the ortho-esters, and the dialkyl acetals of amides can be prepared by literature procedures. For carbonyl compounds: C. A. Buehler, D. E. Pearson, Survey of Organic Synthesis, Vol. 2, pp 480, 532; John Wiley and Sons (1977); for ortho-esters: ibid., p 711; for dialkyl acetals of amides: W. Kantlehner, P. Speh., Ber. Deutsch . Chem . Ges . , 1972, 105, 1340; G. Ege, H. O. Frey, Tetrahedron Lett . , 1982, 4217; S. Hanessian, E. Moralioglu, Can . J. Chem . , 1972, 50, 233; T. Oishi et al., Chem . Pharm . Bull . , 1969, 17, 2314) . The compounds of Formula Ip can be prepared using the procedure illustrated in Method II, Scheme XI. The compounds of Formula 22 can be prepared from the amino compounds of Formula 21 by literature methods (Step 1, G. C. Barrett, C. M. O. A. Martins, J. Chem . Soc Chem . Commun . , 1972, 698; W. Walter, M. Radke, Liebigs Ann . Chem . , 1970, 139, 201; P. Schlack, G. Keil, Liebigs Ann . Chem . , 1963, 661, 164; W. Reid, W. Vond Der Emden, Liebigs Ann. Chem . , 1961, 642, 128). Compounds of Formula Ip can be obtained from compounds of Formula 22 by known methods. For example, to a stirred solution of a compound of Formula 22 in an inert solvent, such as dichloromethane, at a temperature of 20° to 100°C, an alkyl halide, such as iodomethane is added. When the reaction is complete, the solvent is removed to provide, after purification, a compound of Formula Ip. (Step 2, H. Nishiyama et al., Tetrahedron Lett . , 1979, 4405; M. Bercot-Vatteroni, Liebigs Ann . Chem. , 1962, 7, 312; A. A. Goldberg, W. Kelly, J. Chem . Soc , 1948, 1919) . Another method for the preparation of compounds of Formula lo is illustrated in Method III, Scheme XI. Following literature methods, the compounds of Formula 23 can be prepared from compounds of Formula 21 (Step 1) . For R 46 C(=0)N as amides: S. Sandier, W. Karo, Organic Functional Group Preparations (Second Edition), Vol. 1, p 316, Academic Press (1983); for R 46 C(=0)N as carbamates: ibid., (First Edition), Vol 2, p 223, Academic Press (1971); for R 46 C(=0)N as ureas: ibid., (First Edition), Vol. 2, p 135, Academic Press (1971); for R 46 C(=0)N as thiolcarbamate: A. Hajos, Ber. Deutsch . Chem . Ges . , 1961, 94, 2350; G. Harris, I. C. MacWilliam, J. Chem . Soc , 1961, 2053. Compounds of Formula 24 can be prepared from compounds of Formula 23 (Step 2) by literature methods (R. Appel et al., Ber. Deutsch . Chem . Ges . , 1974, 107, 698; K. Fijimoto et al., Chem . Ind. , 1971, 175; W. Reid, R. Christ, Liebigs Ann . Chem . , 1980, 693). The compounds of Formula lo can be obtained from compounds of Formula 24 according to literature methods with the use of reagents such as sulfur nucleophiles (P. Wolkoff et al., Can. J. Chem., 1974, 52, 879; M. Grdinic, V. Hahn, J. Org. Chem., 1965, 30, 2381; J. H. Davies et al., J. Chem. Soc, C, 1968, 431), nitrogen nucleophiles (I. Matsuda et al., J. Chem. Soc, Perkin Trans. I, 1976, 1528; S. Yanagida et al., Bull. Chem. Soc Jpn., 1971, 44, 2182; E. Gedlovska et al., Collect. Czech. Chem. Commun., 1976, 41, 3085), oxygen nucleophiles (S. Knapp, D. V. Patel, Tetrahedron Lett., 1982, 23, 3539; J. E. Rowe, Synthesis, 1980, 114; L. I. Samarai et al., Zh . Org. Khim., 1987, 23, 455), or carbon nucleophiles (H. Quast et al., Liebigs Ann. Chem., 1979, 83; l ~ . G. Clark, E. Cawkill, Tetrahedron Lett., 1975, 2717; W. Reid, P. Weidemann, Ber. Deutsch. Chem. Ges., 1971, 104, 3329) . SCHEME XII 21 IX The nitro compounds of Formula Iq can be prepared from compounds of Formula 21 by oxidation methods known in the literature using oxidizing reagents such as percarboxylic acids. For example, to a solution of an oxidant, such as meta-chloroperbenzoic acid in an inert organic solvent, such as chloroform, an amino compound of Formula 21 is added. The reaction is maintained at a temperature of 20° to 100°C. When the reaction is complete, the reaction mixture is sequentially washed with sodium thiosulfate aqueous solution, sodium bicarbonate aqueous solution, and water. The solvent is then removed to provide, after purification, a nitro compound of Formula Iq. (C. H. Robinson, L. Milewich, P. Hoffer, J. Org. Chem . , 1966, 31, 524; E. Keinan, Y. Mazur, J. Org. , Chem . , 1977, 42, 844; Y. Yost, J. Med. Chem . , 1969, 12, 961) . SCHEME XIII 25. ~ Compounds of Formula Ir can be prepared from compounds of Formula 25, as illustrated in Scheme XIII, following literature methods used to prepare thioamides and thioureas from the corresponding amides and ureas, respectively, using reagents such as sulfur, P 4 S 1 Q' or Lawesson's reagent. For example, to a solution of a compound of Formula 25 in an inert organic solvent such as benzene or acetonitrile, a solution of a sulfurizing reagent, such as P S 10 ^ n tne ~ ~~~~ solvent is added, followed by an inorganic salt, such as sodium bicarbonate. The reaction temperature is maintained at 0° to 100°C. When the reaction is complete, an organic solvent, such as diethyl ether is added and the mixture is washed with a basic aqueous solution, such as sodium bicarbonate and then water. The solvent is removed to give, after purification, a compound of Formula Ir. (H. Alper et al., Angew. Chem . , Int . Ed . Eng . , 1978, 17, 689; J. Perregaard et al., Bull. Soc . Chim . Belg . , 1977, 86, 321; J. Voss, Liebigs Ann . Chem . , 1971, 146, 92; T. Nishio et al., Synthesis, 1989, 396; J. M. Kane, Synthesis, 1987, 912) . SCHEME XIV Method I IX. IS Method II !_. U_ Ifi Compounds of Formula Is can be obtained by one or both of the methods illustrated in Scheme XIV. As shown in Method I, compounds of Formula Is can be obtained from compounds of Formula Ir with the use of reagents containing a NH 2 group such as a primary amine or amides (P. N. Bhargava, V. N. Choubey, Curr. Sci . , 1968, 37, 645; M. E. Baguley, J. A. Elvidge, J. Chem . Soc , 1957, 709; F. Micheel, W. Brunkhorst, Ber. Deutsch . Chem . Ges . , 1955, 88, 481), or hydroxylamines (V. Cerneckij et al., Collect . Czech . Chem . Commun . , 1962, 21, 87; R. Hazard, Bull. Soc . Chim . Fr . , 1949, 228; Sanwa K. K., EP 268,245; J. D. Brion et al., Synthesis, 1983, 220) . The amines, amides, and hydroxylamines can be prepared by literature methods. [For amines: G. A. Buehler, D. E. Pearson, Survey of Organic Synthesis, Vol. 2, p 391, John Wiley and Sons (1977); for amides, ibid., p 813; for hydroxylamines (S. Sandier, W. Karo, Org. Functional Group Preparations, Vol. Ill, p 322, Academic Press, (1972)]. Compounds of Formula Is can also be prepared as illustrated in Method II, Scheme XIV. Compounds of Formula It can be obtained from compounds of Formula Ir by treatment with sources of ammonia. For example, to a stirred solution of a compound of Formula Ir in an inert solvent such as dichloromethane, a source of ammonia, such as ammonia gas or ammonium chloride, is added at a temperature of -20° to 50°C. When the reaction is complete, the solvent is removed to provide, after purification, a compound of Formula It. (Step 1, G. S. Skinner, H. C. Vogt, J. Am . Chem . Soc , 1955, 77, 5440; F. H. S. Curd et al., J. Chem . Soc , 1948, 586; J. S. Morley, J. C. E. Simpson, J. Chem . Soc , 1952, 2617) Compounds of Formula It can be converted to compounds of Formula Is by derivatizing the imino nitrogen. For example, an imino compound of Formula It and an electrophilic reagent such as an acyl chloride are combined and stirred in an inert organic solvent such as chloroform, at a temperature of 0° to 100°C, with or without the use of base, such as pyridine. When the reaction is complete, the reaction mixture is poured into water and extracted with an organic solvent. The solvent is removed to provide, after purification, a compound of Formula Is. (Step 2, J. P. Lokensgard et al., J. Org. Chem . , 1985, 50, 5609; R. Kupfer et al., Chem . Ber . , 1985, 118, 3089; R. Allmann et al., Chem . Ber. , 1986, 119, 2444; J. P. Chetia et al., Synthesis, 1985, 83; F. Matsuda et al., Tetrahdedron Lett . , 1982, 23, 4043) SCHEME XV Method I 21 m Method II 21 23. lu Method III 21 111 The isonitriles of Formula lu can be prepared by one or more of the methods illustrated in Scheme XV. Thus, the amino compounds of Formula 21 can be converted to isonitriles of Formula lu by treatment with dihalocarbenes (Method I) . (L. Malatesta, Gazz , Chim . , 1947, 77, 238; S. R. Sandier and W. Karo, Organic Functional Group Preparations, (second edition) Vol. Ill, p 206, Academic Press, Inc. (1989)). Alternatively, compounds of Formula lu can be prepared as illustrated in Method II. The forma ides of Formula 26 prepared from amino compounds of Formula 21 (Step 1) can be converted to compounds of Formula lu (Step 2) . For example, a compound of Formula 26 and a electrophilic reagent that can serve as a dehydration reagent, such as toluenesulfonyl chloride, and a base, such as pyridine, are mixed at a temperature of 0° to 100°C, with or without the use of an inert organic solvent, such as dichloromethane. When the reaction is complete, the reaction mixture is added to water and extracted with an organic solvent. The combined organic extracts are washed with water. The solvent is removed to provide, after purification, a compound of Formula lu. This process is well documented in the literature (I. Ugi et al., Chem . Ber. , 1961, 94, 2814; W. R. Hertler and E. J. Corey, J. Org. Chem . , 1958, 23, 1221; R. Obrecht et al., Synthesis, 1985, 400). In addition, compounds of Formula lu can be prepared from iodo compounds of Formula 27 (Method III) by literature methods with the use of heavy metal cyanides (S. R. Sandier and W. Karo, Organic Functional Group Preparations (second edition), Vol. Ill, p 206, Academic Press, Inc.; E. G. J. Hartley, J. Chem . Soc , 1916, 109, 1926) . The preparation of the iodo compounds of Formula 17 is described in Scheme V. EXAMPLE 1 Preparation of 3.5-dihydro-5-methyl-2-methylthio-5- phenyl-3- (phenylamino)-4H-imidazol-4-one To a solution of 5-methyl-5-phenyl-3-phenylamino-2- thioxo-4-imidazolidinone (0.1 g, 0.34 mmol) in dichloromethane (10 mL) , iodomethane (0.25 g, 1.75 mmol) and triethylamine (0.18 mL, 1.8 mmol) were added.. The mixture was stirred for 48 h, poured into water (10 L) , and extracted with ethyl acetate (three times with 25 L) . The organic extracts were combined, washed with water, dried (MgS0 ) , and filtered, and the solvent was removed in vacuo to give the title compound as a slightly yellow solid, (95 mg, 90%) , m.p. 132-134°C; ^ NMR (CDC1 3 ) : δ 1.77 (s, 3H) , 2.61 (s, 3H) , 6.15 (s, IH) , 6.70-7.62 (m, 10H) EXAMPLE 2 Preparation of 3,5-_ihy_ro-.-m-_hyl-5-p,enyi-3- (phenylamino)-4H-imidazol-4-one To a solution of 5-methyl-5-phenyl-2-phenylamino-2- thioxo-4-imidazolidinone (0.2 g, 0.6 mmol) in acetone (6 mL) , a solution of Oxone ® (49.5% KHS0 5 ) (0.6 g, 4 mmol in 3.5 mL H 2 0) was added. The reaction mixture was stirred vigorously for 4 min. Ethyl acetate (100 L) and water (20 mL) were added. The mixture was neutralized with aqueous sodium bicarbonate solution. The organic layer was separated, dried (MgS0 ) and filtered, and the solvent was removed in vacuo to give an oil which was purified on a silica gel column eluting with ethyl acetate/hexane (1:1) to afford the title compound (0.13 g, 80%), as a white solid, m.p. 120-121°C; IR (CHC1 3 ) : 1733 cm -1 ; ^-H NMR (CDC1 3 ) : δ 1.77 (s, 3H) , 6.20 (s, IH) , 6.67-7.62 (m, 10H) , 7.92 (S, IH) . EXAMPLE 3 Preparation of 3.5-dihydro-2-methoxy-5-methyl-5-phenyl- 3-(phenylaminoϊ-4H-imidazol-4-one To a solution of ethyl α-[ (methoxythioxomethyl)- amino]-α-methyl-benzeneacetate (0.2 g, 0.75 mmol) in dichloromethane (1 mL) was added iodomethane (0.5 g, 3.5 mmol) followed by the dropwise addition of 1, 8-diazabicyclo[5.4.0]undec-7-ene (0.25 g, 1.6 mmol). The reaction mixture was stirred for 10 minutes, poured into water (10 mL) , and extracted with ethyl acetate (3 times with 10 mL) . The organic extracts were combined, washed with water, dried (MgS0 4 ) , and filtered. The solvent was removed in vacuo to give 0.2 g of ethyl α-[ [methoxy-(methylthio)methylene]- amino]-α-methylbenzeneacetate (95% yield) as an oil. X H NMR (CDC1 3 ) : δ 1.25 (t, J=7 Hz, 3H) , 1.80 (s, 3H) , 2.50 (s, 3H) , 4.98 (s, 3H) , 4.15 (q, J=7 Hz, 2H) , 7.35-7.90 (m, 5H) . To a solution of ethyl α-[ [methoxy(methylthio)- methylene]amino]-α-methylbenzeneacetate (0.2 g, 0.71 mmol) in glacial acetic acid (1 mL) was added anhydrous phenylhydrazine (0.1 g, 0.93 mmol). The reaction mixture was stirred for 15 minutes, poured into aqueous sodium carbonate, and extracted with ethyl acetate. The ethyl acetate extracts were combined, washed with water, dried (MgS0 4 ) , and filtered. The solvent was removed in vacuo to afford an oil which was purified by silica gel chromatography (ethyl acetate:hexanes = 1:2) to give two fractions. Fraction 1 was ethyl α-[ [methoxy(2-phenyl-hydrazino)methylene]- amino-α-methylbenzeneacetate (R f =0.33, 40 mg, 16% yield). ' R NMR (CDC1 3 ) : δ 1.20 (t, J=6.7 Hz, 3H) , 2.00 (s, 3H) , 3.75 (s, 3H) , 4.20 (q, J=6.7 Hz, 2H) , 5.50 (bs, IH) , 6.75 (bs, IH) , 6.90-7.70 (m, 10H) . Fraction 2 was the title compound (R f =0.07, 10 mg, 4.5% yield), m.p. 110-111°C; λ E NMR (CDC1 3 ) : δ 1.78 (s, 3H) , 4.13 (s, 3H) , 6.01 (s, IH) , 6.69-7.67 (m, 10H) . Ethyl α-[ [methoxy(2-phenylhydrazino)methylene]- amino-α-methylbenzeneacetate was converted into the title compound by heating it for 30 seconds in a round- bottomed flask with a hot-air gun. The compound was purified by silica gel chromatography (ethyl acetate:hexane = 1:2). An additional 23 mg (3.3% yield) was obtained. EXAMPLE 4 Preparation of 3.5-d_hydro-5-me_hyl-2-methylthio-5- heptyl-3-(ph_nylami.no)-4H-imi-azol-4-one To ethyl 2-[ [bis(methylthio)methylene]amino]-2- methylnonanoate (4 g, 12.54 mmol) in acetic acid (100 mL) was added phenylhydrazine (1.6 g, 14.8 mmol) and the mixture was stirred for 5 h. The reaction mixture was then slowly poured into enough aqueous sodium carbonate to neutralize the acetic acid. The aqueous mixture was extracted with ethyl acetate. The ethyl acetate extracts were combined, washed with water, dried (MgS0 4 ) , and filtered. The solvent was removed in vacuo to give an oil which was purified by silica gel chromatography (ethyl acetate:hexane = 1:2). The title compound (1.35 g, 32%) was obtained, m.p. 108-110°C, ~ R NMR (CDC1 3 ) : δ 0.86 (t, J=2.4 Hz, 3H) , 1.05-1.38 (m, 10H) , 1.39 (s, 3H) , 1.62 (m, 2H) , 2.51 (s, 3H) , 6.16 (s, IH) , 6.78-7.25 (m, 5H) . EXAMPLE 5 Preparation of 3.5-dihydro-2.5-dimethyl-5-phenyl-3- (phenylamino)-4H-imidazol-4-.one To ethyl α-(acetylamino)-α-methylbenzeneacetate (0.2 g, 0.85 mmol) in carbon tetrachloride. (10 mL) was added phosphorus pentachloride (0.26 g, 1.27 mmol) . The mixture was stirred and heated at reflux for 5 minutes. The solvent was removed in vacuo. The residue was redissolved in dichloromethane (2 mL) and added dropwise to a solution of phenylhydrazine (0.34 g, 3.15 mmol) in dichloromethane (10 mL) . The reaction solution was stirred at room temperature for 24 h, poured into water, and extracted with ethyl acetate. The ethyl acetate extracts were combined, washed with water, dried (MgS0 4 ) , and filtered. The solvent was then removed in vacuo to afford a solid which was recrystallized from 1-chlorobutane to give the title compound (0.15 g, 63.2%). m.p. 110-112°C, ^-H NMR (CDC1 3 ) : 6 1. 63 (s, 3H) , 2 . 16 (s, 3H) , 6.58-7 .50 (m, 10H) , 8 . 69 (s , IH) . EXAMPLE 6 Preparation of 3,5-dihy_.rQ-2-m_thoxy---m_thyl-3- (m-thyl-ph-nylamino)-5-phenyl-4H-imi-a_Ql-4-on_ 5-Methyl-5-phenyl-3-(phenylamino)-2,4- imidizolidine-dione(2.5 g, 8.88 mmol), iodomethane (14 mL) , and silver oxide (2.6 g, 12.59 mmol) were combined and stirred at room temperature for 2 h. The reaction mixture was filtered, and the solvent was removed in vacuo. The residue obtained was stirred with ethyl acetate. The solid which did not dissolve was filtered off and further washed with ethyl acetate. The ethyl acetate filtrate and washes were combined and evaporated in vacuo to give a residue which was purified by silica gel chromatography (ethyl acetate:hexane = 1:2) to afford the title compound (0.2 g, 7.6% yield), m.p. 183-185°C; ' ϋ NMR (CDC1 3 ) : δ 1.72 (s, 3H) , 3.20 (s, 3H) , 4.02 (s, 3H) , 6.50-7.80 (m, 10H) . Additional compounds were prepared using the procedures exemplified above in Examples 1-6, and are listed in Index Table A hereinafter. The compounds referred to in the Tables which follow are illustrated below. The groups R^—R 69 and A, B, E, V, G, J, n, Q, T, and W are as defined in Formula I in the Summary of the Invention. Additional variables are used in the compounds and Tables and are: m, which designates the size of a portion of some substituted R 2 alkyl groups, is 0-18; p, which designates the size of a portion of other substituted R 2 alkyl groups, is 1-19; q and r designate the length of some alkoxyalkyl R 2 groups. The sum of q and r is 2-20. J__ Is. Is. The following abbreviations are used in the Tables which follow. All alkyl groups are the normal isomers unless indicated otherwise . ϊ______l Compounds of Formula I wherein A=0, B=MeS, and: E x E B- H H H H H H H H H H H H H Me Me Me Me Me Me Me E x Me Me Me Me Me Me Me Me Me Me Me Me TABLE 2 Compounds of Formula I wherein R-^Me, R 3 =Ph, oxy)- l)heptyl pyl entyl l 4-Cl-PhO)-3-pyridyl 3-Cl-PhO)-3-pyridyl 2,4-diF-PhO)-2-pyridyl 4-CN-PhO)-4-pyridyl 4-Me-PhO)-2-pyridyl 4-allyl-PhO)-3-pyridyl (3-PhO)PhO)-3-pyridyl hCH=CH-3-ρyridyl 2-F-Ph)CH=CH-2-pyridyl 3-Me-Ph)CH=CH-2-pyridyl 4-CF 3 -Ph)CH=CH-3-pyridyl hCH 2 CH 2 -3-pyridyl 3-Cl-Ph)CH 2 CH 2 -4-pyridyl 2,4-diF-Ph)CH 2 CH 2 -3-pyridyl 3-Me-Ph)CH 2 CH 2 -2-pyridyl h0CH 2 -3-pyridyl 2-F-Ph)OCH 2 -2-pyridyl 2,4-diF-Ph)OCH 2 -3-pyridyl 3-Me-Ph)OCH 2 -2-pyridyl hCH 2 -3-pyridyl 3-Br-Ph)CH 2 -3-ρyridyl hS-3-pyridyl 3-Cl-Ph)S-4-pyridyl 2,4-diF-Ph)S-3-pyridyl 3-Me-Ph)S-2-pyridyl h-3-pyridyl 3-Me-Ph)-2-ρyridyl 4-MeO-Ph)-2-pyridyl hCH 2 0-3-pyridyl 2-F-Ph)CH 2 0-3-pyridyl 2, 4-diF-Ph)CH 2 0-4-pyridyl 4-N0 2 -Ph)CH 2 0-3-pyridyl 3-Me-Ph)CH 2 0-3-pyridyl 4-BuO-Ph)CH 2 0-3-pyridyl 6-Ph0-3-pyr dy l m Z H 2 0 PhOC(=0) 3 O (4-Et0-Ph)0C(=0) 6 O (4-pyridyl)0C(=0) 3 N-Me Ph Compounds of Formula I wherein and: nic acid salt) idyl dyl idyl ridyl ridyl I______l Compounds of Formula I wherein S, and: l ________ Compounds of Formula I wherein , and: l ____ε__ Compounds of Formula I wherein l Ph hthalenyl ienyl thienyl enyl ienyl TABLE 1Q Compounds of Formula I wherein R 1 =Me, R 2 =Ph =0)NR 19 R 20 , B=MeS, and: 3 -Ph H S-Ph H Me Et -CH 2 CH 2 CH 2 CH 2 - -CH 2 CH 2 CH 2 CH 2 CH 2 - -CH 2 CH 2 OCH 2 CH 2 - -CH 2 CH(Me)OCH(Me)CH 2 - TABLE 11 Compounds of Formula I wherein , and: _. EtOC(=0) (4-Cl-Ph)NH(C=0) MeNHC(=0) (4-N0 2 -Ph)NHC(=0) BuNHC(=0) (4-CF 3 -Ph)NHC(=0) CH 3 (CH 2 ) 5 NHC(=0) (4-MeS-Ph)NHC<-=0) Ph-NH(C=0) TABLE 12 Compounds of Formula I wherein TAB E 13 Compounds of Formula I wherein R 2 =Ph, R 3 =Ph, R 4 =H, A=N-H (HBr salt), B=MeS, and: E B 1 Me allyl Et cyclopropyl CF- vinyl B A & 1 CH 3 CH=CHCH 2 4-Me-Bzl MeO(C=0) 4-CF 3 -Bzl Bzl 4-MeO-Bzl 4-Cl-Bzl TABLE 14 Compounds of Formula I wherein l - - -pyr y TABLE 15 Compounds of Formula I wherein R 1 =Me, R 2 =Ph, R 3 =Ph, R =H, A=0, and: £ H cyano Cl NC Br S=C=N F 0=C=N 1 nitro HSCH 2 Me 0 2 NCH 2 Et 0 2 N(CH 2 ) 2 C 3 «7 N≡CCH 2 Me 2 CH N≡CCH(Me) C H 9 C=C=NCH 2 C 8 H 17 S=C=NCH 2 CH 2 C1 0=C=N(CH 2 ) 2 CH 2 Br S=C=N(CH 2 ) 2 CH 2 F MeNHCH 2 CF 3 Me 2 NCH 2 CH 2 C1CH 2 MeNH(CH 2 ) 2 MeOCH 2 CH 2 =CHCH 2 NHCH 2 EtOCH 2 cyclopropyl-NMeCH 2 MeO(CH 2 ) 2 cyclopropyl-NHCH 2 FCH 2 OCH 2 HC=CCH 2 NMeCH 2 C1CH 2 CH 2 0CH 2 (-CH 2 CH 2 CH 2 CH 2 -)NCH MeOCH 2 OCH 2 (-CH 2 CH 2 OCH 2 CH -)NCH 2 CH 2 MeO(CH 2 ) 2 OCH 2 HON=CHCH 2 EtOCH 2 OCH 2 MeON=CHCH 2 MeSCH 2 MeON=C(Me)CH 2 EtSCH 2 EtON=CH 2 MeS(CH 2 ) 2 MeN=CHCH 2 MeSCH(Me) EtN=CHCH 2 C1CH 2 SCH 2 FCH 2 ON=CHCH 2 CF 3 SCH 2 C1CH 2 CH 2 N=CHCH 2 CH 2 =CHCH 2 OCH 2 MeNHN=CHCH 2 CH 2 =CHCH 2 0(CH 2 ) 2 Me 2 NN=CHCH 2 HC≡CCH 2 OCH 2 MeOC(=0)CH 2 HC≡CCH 2 0(CH 2 ) 2 HOC(=0)CH 2 MeS0 2 CH 2 HC(=0)OCH 2 Me 2 CHS0 2 CH 2 CH(Et) MeC(=0)OCH 2 CF 3 S0 2 CH 2 HC(=0)SCH 2 HOCH 2 MeC(=0)SCH 2 HO(CH 2 ) 2 HC(=0)NHCH 2 E £ HC(=0)N(Me)CH 2 EtOC(=0) MeC(=0)NHCH 2 MeSC(=0) Me 2 CHCH 2 C(=0)0(CH ) 2 EtSC(=0) CH(Br)=CHCH 2 C(=0)OCH(Me) MeSC(=S) H 2 NC(=0)CH 2 EtSC(=S) MeNHC(=0)CH 2 H 2 C=CHCH 2 OC(=0) Me 2 NC(=0)CH 2 CF 3 CH=CHCH 2 SC(=S) MeNHC(=0)OCH 2 H 2 NN=CH CH 2 =CH H 2 NN=C(Me) CH 3 CH=CH MeNHN=CH CH 2 =CHCH 2 Me 2 NN=C(Me) F 2 C=CH EtNHN=CH C1CH 2 CH=CHCH 2 H 2 NC(=0) BrCH=CH(CH 2 ) 2 MeNHC(=0) N≡CCH=CH Me 2 NC(=0) EtC(N≡C)=CH C 5 H 11 NHN=CH (O) 2 NCH=CH 2 MeO HC≡C EtO MeCsC C3H7O HC≡CCH 2 Me 2 CHO CH 2 FC≡CCH 2 C1CH 2 CH 2 0 EtOC(=0)C≡C CF 3 0 cyclopropyl NsCCH 2 0 (-CH 2 CF 2 -)CH N0 2 CH 2 0 HON=CH MeOCH 2 0 HON=C(Me) MeO(CH 2 ) 2 0 MeON=CH CH 2 F0CH 2 0 MeON=C(Me) MeOCH 2 OCH 2 0 EtON=CH MeO(CH 2 ) 2 OCH 2 0 MeN=CH MeSCH 2 CH 2 0 MeN=C(Me) C 3 H 7 0(CH 2 ) 2 0 EtN=CH Me 2 C(Br)CH OCH(Me)O CH 2 =CHCH 2 N=CH EtO(CH 2 ) 2 0(CH 2 ) 2 0 CH 2 =CHCH 2 ON=CH Me 2 NCH 2 0 MeOC(=0) , Me 2 N(CH 2 ) 2 0 E £ (-CH 2 CH 2 CH 2 CH 2 -)NCH 2 0 H 2 C=CHCH 2 0 (-CH 2 CH 2 OCH 2 CH 2 -)NCH 2 CH 2 0 Me 2 CHCH=CHCH 2 0 HON=CHCH 2 0 F 2 C=CHCH 2 0 MeON=CHCH 2 0 CH 2 (Br)C=CHCH 0 HON=C(Me)CH 2 0 HC=CCH 2 0 MeON=C(Me)CH 2 0 cyclopropyl-0 MeN=CHCH 2 0 HC(=0)O MeN=C(Me)CH 2 0 MeC(=0)0 MeNHN=CHCH 2 0 C 4 H 9 C(=0)0 Me 2 NN=CHCH 2 0 C1CH 2 C(=0)O Me 2 NN=C(Me)CH 0 CH 2 «=CHC(=0)0 MeNHN=C(Me)CH 2 0 Me 2 C=CHC<=0)0 HOC(=0)CH 2 0 CF 3 CH=CHCH 2 C(=0)0 MeOC(=0)CH 2 0 HC(=NMe)0 MeOC(=0)0CH 2 0 MeC(=NMe)0 HC(=0)OCH 2 0 EtCH(Me)C(=NEt)0 MeC(=0)OCH 2 0 C1CH 2 C(=N(C 3 H 7 ))0 HC(=0)SCH 2 0 CH 2 =CHC(=NCH(Me) )0 MeC(=0)SCH 2 0 C1 2 C=CHCH 2 C(=N(C 4 H 7 ) )O H 2 NC(=0)CH 2 0 MeOC(=0)O MeNHC(=0)CH 2 0 Et0C(=O)O Me 2 NC(=0)CH 2 0 EtCH=CHC(=NEt)0 MeNHC(=0)0(CH 2 ) 2 0 MeNHC(=0)0 Me 2 NHC(=0)0(CH 2 ) 2 0 Me 2 NC(=0)O C 3 H 7 NHC(=0)CH 2 0 MeCH=CHCH 2 (Me)C(=0)O HC≡CCH 2 NHC(=0)CH 2 0 CF 3 (CH 2 ) 2 N(Et)C(=0)0 MeO(CH 2 ) 3 N(Me)C(=0)O(CH 2 ) 2 0 CH 2 =C(Cl)CH 2 N(C 3 H 7 )C(=0)O MeOC(=N(Me))CH 2 0 MeS(O) 2 0 MeOC(=0)NHCH 2 0 C 4 H 9 S(0) 2 0 MeOC(=0) (Me)CH 2 0 Me 2 CHCHClS (O) 2 0 HC(=0)NHCH 2 0 EtCH=CHS (O) 2 0 MeC(=0) HCH 2 0 CH 2 =N0 MeC(=0)N(Me)CH 2 0 MeCH=NO HC(=NMe)0(CH 2 ) 2 0 Me 2 C=NO C 3 H 7 C(=0)N(Me)CH 2 0 EtCH=NO £ £ C 4 H 9 C (Me) =NO CF 3 CH 2 CH=CHC(=N(cyclopropyl) ) ■ CF 3 CH 2 C (Et ) =NO N(Me) CH 2 =CHC (C 3 H 7 ) =NO C1CH=CHCH 2 0C(=0)N(Et) C1CH=CHCH 2 C(CH 2 (Cl) )=N0 C1 2 C=CHCH 2 NHC(=0)N(Et) EtCH(Me)OC(Et)=N0 HON(CH 3 ) C1CH 2 CH 2 0C(C 3 H 7 )=NO MeON(CH 3 ) MeCH=CHCH 2 OC(CH 2 (Cl) )=NO EtON(CH 3 ) MeNH CH 2 =CHCH 2 ON(CH 3 ) EtNH CF 2 =CHCH 2 ON(CH 3 ) CH 2 =CHCH 2 NH H 2 C=N HC≡CCH 2 NH MeCH=N HC(=0)NH CF 3 CH=N Me(=0)NH MeNHCH=N HC(=NMe)NH Me 2 NCH=N MeC(=NMe)NH MeOCH=N MeOC(=0)NH EtOCH=N MeNHC(=0)NH MeSCH=N Me 2 NC(=0)NH EtSCH=N Me 2 N C 4 H 9 C(H)=N EtN(Me) ClCH 2 C(Me)=N HC≡CCH N(Me) CH 2 =CHCH 2 C(CF 3 )=N HC(=0)N(Me) CH 2 BrCH=CHCH 2 C(Et)=N Me(=0)N(Me) MeNHC(C 3 H 9 )=N HC(=NMe)N(Me) CH 2 =CHCH 2 N(Me)C(CH 2 F)=N MeC(=NMe)N(Me) H 3 COC(Me)=N MeOC(=0)N(Me) CF 3 CH 2 OC(CH 2 C1)=N Me 2 NC(=0)N(Me) C 4 H 9 SC(C 3 H 9 )=N C 3 H 7 C(=0)N(Et) CH 2 =CH(CH 2 ) 2 SC(CF 3 )=N EtCHClC(=0)N(C 3 H 7 ) CH 2 (Br) (CH 2 ) 2 SC(C 4 H 9 )=N CH 2 =CHC(=0)N(C 4 H 9 ) (Me) 2 C=N EtC(Cl)=CHC(=0)NH (Me) 2 NC(Me)=N Me 2 CHC(=N(Me) )NH MeOC(Me)=N CH 2 ClC(=N(Et) )N(Me) MeSC(Me)=N MeCH=CHCH 2 C(=N(C 3 H 7 ) )NH (Me) 2 NC(NH(Me) )=N CH 2 =CHCH 2 (Me)C(NH(Et) )=N £ E Me 2 NC (=0) OCH 2 S Me 2 NC(=0)S BrCH 2 CH=CHCH 2 N(C 3 H g )C(=0)CH 2 S C1CH=CHCH 2 CH 2 N(Et)C(=0)S 3-CF 3 N(C 3 H 9 )C(=0)0(CH 2 ) 2 S MeS (O) 2 MeOC(=0)NHCH 2 S MeS (O) MeOC(=0)N(Me)CH 2 S EtS(0) 2 HC(=0)NHCH 2 S EtS (O) MeC(=0)NHCH 2 S CH 2 =CHS (O) 2 MeC(=0)N(Me)CH 2 S CH 2 =CHS (O) HC(=0)N(Me)CH 2 S CH 2 =CHCH 2 S (O) 2 Me 2 CHC(=0)N(Me) (CH 2 ) 2 S CH 2 =CHCH 2 S (O) CF 2 =CHCH 2 S CH 2 (C1)CH=CHS(0) N≡CCH=CHCH 2 S HC=CCH 2 S (O) 2 0 2 NCH=CH 2 (CH 2 ) 2 S MeC=CCH(Me)S(0) MeOC(=0)CH=CHCH 2 S MeOCH 2 S (O) 2 EtC=CCH 2 S MeOCH 2 S (0) CH 2 (C1)C≡CCH 2 S EtO(CH 2 ) 2 S(0) 2 CF 3 (CH 2 ) 2 C≡CCH 2 S H 2 NS0 2 NC-C≡C(CH 2 ) 2 S MeNHS0 2 C 4 H 9 OC(=0)C≡CCH 2 S (Me) 2 NS0 2 cyclopropyl-S EtNHS0 2 (-CH 2 (CH 2 ) 3 CH 2 -)C(Cl)S Me 2 CHCH 2 (Me)S0 2 CH(=0)S CF 3 (CH 2 ) 2 N(Et)S0 2 MeC(=0)S CH 3 CH 2 CH 2 N(C 3 H 9 )S0 2 CH 2 =CHCH 2 C(=0)S FCH=CHCH 2 N(C 4 H 9 )S0 2 MeOC(=0) S CH(=0)NHS(0) 2 C1CH=CHCH 2 0C(=0)S MeC(=0)NHS(0) 2 Me 2 NC(=0)S MeC(=0)N(Me)S(0) 2 MeNHC(=0) S 3-phenoxypropyl 3-phenoxyρropyl 3-phenoxypropyl Formulation/Utility Compounds of this invention will generally be used in formulation with an agriculturally suitable composition. The fungicidal compositions of the present invention comprise an effective amount of at least one compound of Formula I as defined above and at least one of (a) a surfactant, (b) an organic solvent, and (c) at least one solid or liquid diluent. Useful formulations can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates, dry flowables and the like. Sprayable formulations can be extended in suitable media and used at spray volumes from about one to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations will typically contain effective amounts of active ingredient, diluent and surfactant within the following approximate ranges which add up 100 weight percent. Weight Percent Typical solid diluents are described in Watkins, et al., Handbook of Insecticide Dust Diluents and Carriers, 2nd Ed., Dorland Books, Caldwell, New Jersey. Typical liquid diluents and solvents are described in Marsden, Solvents Guide, 2nd Ed., Interscience, New York, 1950. McCutcheon ' s Detergents and Emulsifiers Annual , Allured Publ. Corp., Ridgewood, New Jersey, as well as Sisely and Wood, Encyclopedia of Surface Active Agents, Chemical Publ. Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foam, caking, corrosion, microbiological growth, etc. Methods for formulating such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer mill or fluid energy mill. Water-dispersible granules can be produced be agglomerating a fine powder composition; see for example, Cross et al., Pesticide Formulations, Washington, D.C., 1988, pp 251-259. Suspensions are prepared by wet-milling; see, for example, U.S. 3,060,084. Granules and pellets can be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See Browning, "Agglomeration", Chemical Engineering, December 4, 1967, pp 147-148, Perry 's Chemical Engineer 's Handbook, 4th Ed., McGraw-Hill, New York, 1963, pp 8-57 and following, and WO 91/13546. Pellets can be prepared as described in U.S. 4,172,714. Water-dispersible and water-soluble granules can be prepared as taught in DE 3,246,493. For further information regarding the art of formulation, see U.S. 3,235,361, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41; U.S. 3,309,192, Col. 5, line 43 through Col. 7, line 62 and Examples 8, _2, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182; U.S. 2,891,855, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4; Klingman, JVeed Control as a Science, John Wiley and Sons, Inc., New York, 1961, pp 81-96; and Hance et al., Weed Control Handbook, 8th Ed., Blackwell Scientific Publications, Oxford, 1989. In the following Examples, all percentages are by weight and all formulations are worked up in conventional ways. Compound numbers refer to Index Table A hereinafter. Example A Wettable Powder Compound 1 65.0% dodecylphenol polyethylene glycol ether 2.0% sodium ligninsulfonate 4.0% sodium silicoaluminate 6.0% montmorillonite (calcined) 23.0%. Example B Granule Compound 1 10.0% attapulgite granules (low volative matter, 0.71/0.30 mm; U.S.S. No. 25-50 sieves) 90.0%. Example C Extruded Pellet Compound 1 25.0% anhydrous sodium sulfate 10.0% crude calcium ligninsulfonate 5.0% sodium alkylnaphthalenesulfonate 1.0% calcium/magnesium bentonite 59.0%. Example D Emulsifiable Concentrate Compound 1 20.0% blend of oil soluble sulfonates and polyoxyethylene ethers 10.0% isophorone 70.0%. The compounds of this invention are useful as plant disease control agents. The present invention therefore further comprises a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof to be protected, or to the plant seed or seedling to be protected, an effective amount of a compound of Formula I or a fungicidal composition containing said compound. The compounds and compositions of this invention provide control of diseases caused by a broad spectrum of fungal plant pathogens in the Basidiojnycete, Ascomycete, Oomycete and Deuteromycete classes. They are effective in controlling a broad spectrum of plant diseases, particularly foliar pathogens of ornamental, vegetable, field, cereal, and fruit crops. These pathogens include Plasmopara viticola, Phytophthora infestans, Peronospora tabacina, Pseudoperonospora cubensis, Pythium aphanidermatum, Alternaria brassicae, Septoria nodorum, Cercosporidium personatum, Cercospora arachidicola, Pseudo- cercosporella herpotrichoides, Cercospora beticola, Botrytis cinerea, Monilinia fructicola, Pyricularia oryzae, Podosphaera leucotricha, Venturia inaequalis, Erysiphe graminis, ϋncinula necatur, Puccinia recondita, Puccinia graminis, Hemileia vastatrix, Puccinia striiformis, Puccinia arachidis, Rhizoctonia solani, Sphaerotheca fuliginea, Fusarium oxysporum, Verticillium dahliae, Pythium aphanidermatum, Phytophthora megasperma and other generea and species closely related to these pathogens. Compounds of this invention can also be mixed with one or more other insecticides, fungicides, nematocides, bactericides, acaricides, semiochemicals, repellants, attractants, pheromones, feeding stimulants or other biologically active compounds to form a multi- component pesticide giving an even broader spectrum of agricultural protection. Examples of other agricultural protectants with which compounds of this invention can be formulated are: insecticides such as monocrotophos, carbofuran, tetrachlorvinphos, malathion, parathion—methyl, methomyl, chlordimeform, diazinon, deltamethrin, oxamyl, fenvalerate, esfenvalerate, permethrin, profenofos, sulprofos, triflumuron, diflubenzuron, methoprene, buprofezin, thiodicarb, acephate, azinphosmethyl, chlorpyrifos, dimethoate, fipronil, flufenprox, fonophos, isofenphos, methidathion, methamidophos, phosmet, phosphamidon, phosalone, pirirαicarb, phorate, terbufos, trichlorfon, methoxychlor, bifenthrin, biphenate, cyfluthrin, fenpropathrin, fluvalinate, flucythrinate, tralomethrin, metaldehyde and rotenone; fungicides such as carbendazim, thiuram, dodine, maneb, chloroneb, benomyl, cymoxanil, fenpropidine, fenpropimorph, triadimefon, captan, thiophanate-methyl, thiabendazole, phosethyl-Al, chlorothalonil, dichloran, metalaxyl, captafol, iprodione, oxadixyl, vinclozolin, kasugamycin, myclobutanil, tebuconazole, difeno- conazole, diniconazole, fluquinconazole, ipconazole, metconazole, penconazole, propiconazole, uniconzole, flutriafol, prochloraz, pyrifenox, fenarimol, triadimenol, diclobutrazol, copper oxychloride, furalaxyl, folpet, flusilazol, blasticidin S, diclomezine, edifenphos, isoprothiolane, iprobenfos, mepronil, neo-asozin, pencycuron, probenazole, pyroquilon, tricyclazole, validamycin, and flutolanil; nematocides such as aldoxycarb, fenamiphos and fosthietan; bactericides such as oxytetracyline, streptomycin and tribasic copper sulfate; acaricides such as binapacryl, oxythioquinox, chlorobenzilate, dicofol, dienochlor, cyhexatin, hexythiazox, amitraz, propargite, tebufenpyrad and fenbutatin oxide; and biological agents such as Bacillus thuringiensis, baculovirus and avermectin B. In certain instances, combinations with other fungicides having a similiar spectrum of control but a different mode of action will be particularly advantageous for resistance management. Plant disease control is ordinarily accomplished by applying an effective amount of a compound of this invention either pre— or post—infection, to the portion of the plant to be protected such as the roots, stems, foliage, fruit, seeds, tubers or bulbs, or to the media (soil or sand) in which the plants to be protected are growing. The compounds can also be applied to the seed to protect the seed and seedling. Rates of application for these compounds can be influenced by many factors of the environment and should be determined under actual use conditions. Foliage can normally be protected when treated at a rate of from less than 1 g/ha to 5,000 g/ha of active ingredient. Seed and seedlings can normally be protected when seed is treated at a rate of from 0.1 to 10 g per kilogram of seed. The following Tests demonstrate the control efficacy of compounds of this invention on specific pathogens. The pathogen control protection afforded by the compounds is not limited, however, to these species. See Index Table A for compound descriptions. Test compounds were first dissolved in acetone in an amount equal to 3% of the final volume and then suspended at a concentration of 200 ppm in purified water containing 250 ppm of the surfactant Trem ® 014 (polyhydric alcohol esters) . The resulting test suspensions were then used in the following tests. TJ_£_ __ The test suspension was sprayed to the point of run-off on wheat seedlings. The following day the seedlings were inoculated with a spore dust of Erysiphe graminis f. sp. tritici, (the causal agent of wheat powdery mildew) and incubated in a growth chamber at 20°C for 7 days, after which disease ratings were made. TEST B The test suspension was sprayed to the point of run-off on wheat seedlings. The following day the seedlings were inoculated with a spore suspension of Puccinia recondita (the causal agent of wheat leaf rust) and incubated in a saturated atmosphere at 20°C for 24 h, and then moved to a growth chamber at 20°C for 6 days, after which disease ratings were made. TEST C The test suspension was sprayed to the point of run-off on rice seedlings. The following day the seedlings were inoculated with a spore suspension of Pyricularia oryzae (the causal agent of rice blast) and incubated in a saturated atmosphere at 27°C for 24 h, and then moved to a growth chamber at 30°C for 5 days, after which disease ratings were made. TEST D The test suspension was sprayed to the point of run-off on tomato seedlings. The following day the seedlings were inoculated with a spore suspension of Phytophthora infestans (the causal agent of potato and tomato late blight) and incubated in a saturated atmosphere at 20°C for 24 h, and then moved to a growth chamber at 20°C for 5 days, after which disease ratings were made. TJ____J_ The test suspension was sprayed to the point of run-off on potato seedlings. The following day the seedlings were inoculated with a spore suspension of Phytophthora infestans (the causal agent of potato and tomato late blight) and incubated in a saturated atmosphere at 20°C for 24 h, and then moved to a growth chamber at 20°C for 5 days, after which disease ratings were made. TEST F The test suspension was sprayed to the point of run-off on grape seedlings. The following day the seedlings were inoculated with a spore suspension of Plasmopara viticola (the causal agent of grape downy mildew) and incubated in a saturated atmosphere at 20°C for 24 h, moved to a growth chamber at 20°C for 6 days,and then incubated in a saturated atmosphere at 20°C for 24 h, after which disease ratings were made. TEST G The test suspension was sprayed to the point of run-off on cucumber seedlings. The following day the seedlings were inoculated with a spore suspension of Botrytis cinerea (the causal agent of gray mold on many crops) and incubated in a saturated atmosphere at 20°C for 48 h, and moved to a growth chamber at 20°C for 5 days, after which disease ratings were made. Index Table A Compounds of Formula I wherein A=0 and: Index Table B Cmpd No. 1 H NMR Data (CDCl-^, 5) 14 1.48 (d, J=6.8 Hz, 3H) , 1.52 (d, J=6.8 Hz, 3H) , 1.76 (s, 3H), 4.03 (m, J=6.8 Hz, IH), 6.10 (broad s, IH) , 6.93-7.62 (m, 10H) 19 major isomer: 61.27 (t, J=6.5 Hz, 3H) , 1.79 (s, 3H) , 3.60 (m, 2H) , 4.52 ( , 2H) , 6.75-7.65 (m, 10H) minor isomer: δ 1.06 (t, J=6.5 Hz, 3H), 1.77 (s, 3H), 3.60 (m, 2H) , 4.52 (m, 2H) , 6.60-7.65 (m, 10H) 22 1.30 (t, J=7.4 Hz, 3H) , 1.68 (s, 3H) , 2.55 (q, J=7.4 Hz, 2H), 6.70 (s, IH) , 6.52-7.60 ( , 10H) 34 0.95-1.30 (m, 8H) , 1.23 (s, 3H) , 1.50-2.00 (m, 4H) , 2.45 (s, 3H) , 4.78-5.12 (m, 2H) , 5.50-5.92 (m, IH) , 6.40 (s, IH), 6.61-7.30 (m, 5H) 35 1.04 (t, J=7.6 Hz, 3H), 1.73 (s, 3H) , 1.84 (m, 2H) , 2.77 (q, J=7.6 Hz, 2H) , 6.25 (s, IH) , 6.58-7.63 (m, 10H) Results for Tests A-G are given in Table C. In the table, a rating of 100 indicates 100% disease control and a rating of 0 indicates no disease control (relative to the controls) . NT = not tested. TABLE C Cropd No. 1 2 The compound was sprayed at a concentration of 40 ppm The compound was sprayed at a concentration of 100 ppm

Claims: What is claimed is: 1. A compound of Formula I I wherein: A is 0; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P (=0) (C 1 -C 4 alkyl) 2 ; or OG; G is H; C^ ^ -Cg alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C(=0) (^-0 4 alkyl); C(=0) (C 1 -C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 21 ; OR 29 ; NR 49 R 63 ; N=CR 45 R 46 ; SR 47 ; S(0) n R 48 ; or S0 2 NR 49 R<5°; n is 1 or 2; R 1 is C x -C 4 alkyl; C^C, ! haloalkyl; C 3 -C 6 cycloalkyl; C 2 -C 4 alkenyl; C 2 -C 4 alkoxy- carbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is C 1 -C 20 alkyl optionally substituted with R 22 ; C 2 -C 20 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 0CH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 ) CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH 2 ~, —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH 2 ) CH 2 — , —CH 2 CH 2 0CH 2 CH 2 ~, —CH 2 CH 2 SCH 2 CH 2 —, R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phen lmethyl; R 4 is H or methyl; R 5 is halogen; nitro; cyano; C^Cg alkyl; C 5 -C 6 cycloalkyl; C^Cg haloalkyl; C^Cg alkylthio; Ci-Cg haloalkylthio; C j^ -Cg alkoxy; C-^Cg haloalkoxy; C 5 -Cg cycloalkyloxy; C 2 _C 6 alkoxyalkyl; C 2 -Cg alkoxyalkoxy; C 3 -Cg alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl; C 3 _C 6 haloalkynyl; C 3 -C 6 alkynyloxy; C^Cg alkylsulfonyl; C j^ -Cg haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxymethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC(=0) HR 28 ; -C(=0)0R 28 ; or -OC(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; Cχ-Q*_ \ alkyl; trifluoro¬ methyl; methylthio; or C 1 -C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or c l ~ c 4 alkyl; R 9 is C j^ -C j^ s alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C j _.____.C 4 alkyl, trifluoromethyl, C 1 -C 4 alkylthio, C j -^ alkoxy and trifluoromethoxy; R 11 and R 36 are independently C^-Cg alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; C 1 -C 8 alkyl optionally substituted with C 1 -C 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; C 1 -C 17 alkyl optionally substituted with R 31 ; C 2 -C 17 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 4 -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C -C 5 alkoxycarbonyl; R 17 and R 18 are independently C 1 -C 18 alkyl optionally substituted with R 23 ; C 2 -C 10 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; c 3 -c i 2 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 6 -C 7 cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; C^CJ Q alkyl; C 5 -C 6 cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH 2 ~, —CH 2 (CH 2 ) CH 2 —, —CH 2 (CH 2 ) CH 2 — , -CH 2 CH 2 0CH 2 CH 2 -, -CH 2 CH(Me)CH 2 CH( e)CH 2 -, and -CH 2 CH(Me)OCH(Me)CH 2 -; R 21 is C___-C 8 alkyl optionally substituted with R 51 ; C 2 -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)SR 53 ; C(=NR 55 )0R 53 ; C(=S)SR 53 ; C(=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is O; NR 55 ; or a direct bond; R 22 is cyano; nitro; C 1 -C ιg alkylthio; C____-C____ 9 alkyl- sulfinyl; C j -C^ haloalkoxy; C 5 -C 6 cyclo¬ alkyloxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; C -C j^ g alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 8 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 39 R 40 N; (C j -^ alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -C 6 cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is O or S; Q is O or N-T-W; T is O; NR 37 ; or a direct bond; W is H; C j -Cj j alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)OR 28 ; or C(=0)NR 28 R 14 ; R 23 is 1-3 halogen; C 1 -C 12 alkoxy; C 1 -C 12 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; C___-Cg alkyl; C j -Cg haloalkyl; C^ ^ -Cg alkoxy; C j -C haloalkoxy; C 1 -C 4 alkylsulfonyl; C -C 6 alkoxyalkyl; ^-0 4 alkyl¬ thio; C 5 -C 6 cycloalkyl; C 5 -C 6 cycloalkyloxy; C 2 -Cg alkenyl; C 2 -Cg haloalkenyl; C 2 -Cg alkynyl; hydroxycarbonyl; C -C 4 alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is C 1 -C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is C- L -Cs alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(C 1 -C 4 alkyl) ]OR 53 ; C(=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C_ j _-C 4 alkyl, trifluoromethyl, C___-C alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; C 1 -C 18 alkoxy; allyloxy; C j -C j e alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C -C 5 alkoxy¬ carbonyl; R 32 is 1-3 halogen; or C -Z^ alkoxy; R 35 is cyano; nitro; C 1 -C 17 alkylthio; C___-C 17 alkyl¬ sulfinyl; C___-C 17 haloalkoxy; C 5 -C 6 cycloalkyl- oxy; C 2 -C 17 haloalkenyl; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C 1 -C 17 alkylsulfonyl; C -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 0 NC(=O)O; R 0 R 39 N; (C 1 -C 4 alkoxy) 2 P (=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra- hydropyranyl; 2-tetrahydropyranyloxy; C___-C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 _C 17 haloalkoxyalkoxy; R 37 is H; C j -C alkyl; or phenyl optionally substituted with R 7 ; R 39 is C j -C j g alkyl; C 2 -C 19 alkylcarbonyl; C 2 -C 19 alkoxycarbonyl; (R 9 R 40 N)C=O; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; C j -C ] ^ alkylthio; C 1 -C 17 alkylsulfinyl; C j -C;^ haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; C 1 -C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 0C(=0)0; R 28 R 40 NC (=0)0; R 40 R 39 N; (C_ , -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenyl¬ sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; C 1 -C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; R 42 is cyano; nitro; C j -C^ alkylthio; C___-C 17 alkyl- sulfinyl; C 1 -C 17 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C j -C j -y alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)O; R 40 R 39 N; (C 3. -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 1 R 38 N+; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; C___-C 17 alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; C j -C alkoxy; c ι -c 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; C___-Cg alkylthio; C j -C alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 9 R 50 ; or R 62 ; R 45 is H; C J -C 4 alkyl; C^-C^ haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 54 R 55 ; or SR 54 ; R 46 is H; C 1 -C 4 alkyl; C___-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is C j -Cs alkyl optionally substituted with R 44 ; c 3 -c 6 alkenyl or C 3 -Cg alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(C 1 -C 4 alkyl) ]OR 53 ; or C(=0)NR 53 R 56 ; R 48 is C_ j _-C 6 alkyl; C 2 -C 6 alkenyl; C 2 -C 6 halo¬ alkenyl; C 2 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; C J -C 4 alkyl; C 3 -C 4 alkenyl; or cyclo¬ propyl; R 50 is H; C___-C 6 alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -Cg alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH ) -; -(CH 2 ) 5 - or -CH 2 CH 2 OCH 2 CH 2 -; R 51 is 1-3 halogen; C j -Cg alkoxy; C 2 -C 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; C j -Cg alkylthio; C j -C haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -Cg alkynyl¬ oxy; C j -Cg alkylsulfonyl; C___-Cg haloalkyl- sulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 9 R 50 ; or R 62 ; R 52 is H; C- L -C ή alkyl; C___-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; C j^ -Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -Cg alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or C x -C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or C j -0 4 alkyl; R 60 is C___-C 4 alkyl; C^d haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; C J -C 4 alkyl; C 1 -C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R62 i s C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; C(=NR 55 )OR 53 ; C(=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC(=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC(=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N(R 56 ) C(=0)OR 53 ; or N(R 56 ) C(=NR 55 )NR 53 R 54 ; R 63 is H; C j -C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -Cg alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is C 1 -C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently C- L -C 4 alkyl; c 3 -c 4 haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; C j -C .4 alkyl; ^-0 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; C___-C 4 alkyl; C___-C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20. 2. A compound of Claim 1 wherein: R 1 is C_ι_-C 4 alkyl; C___-C 4 haloalkyl; C 3 -C 4 cycloalkyl; or C 2 -C 4 alkenyl; R 21 is C___-C 4 alkyl optionally substituted with R 51 ; C 2 -C alkenyl, C 2 -C 8 alkynyl, or cyclopropyl each optionally substituted with 1-3 halogen; C(=N-V-R 53 )H; C(=N-V-R 53 ) (C j -C^ alkyl); C (=0) OR 53 ; C (=0) SR 53 ; ~C (=S) SR 53 ; or C(=0)NR 53 R 56 ; R 29 is C- L -C 4 alkyl optionally substituted with R 44 ; C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, or cyclopropyl each optionally substituted with 1-3 halogen; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C(=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 44 is 1-3 halogen; cyano; nitro; C___-C alkoxy; C J -C 4 haloalkoxy; C 2 -C 4 alkoxyalkoxy; C___-C 4 alkylthio; or R 62 ; R 45 is H; C____-C 4 alkyl; C 1 -C 4 haloalkyl; C 2 -C 4 alkenyl; or C 2 -C 4 haloalkenyl; R 46 is H; C 1 -C alkyl; C j -0 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is C J -C alkyl optionally substituted with R 44 ; C 3 -C 4 alkenyl or C 3 -C 4 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; C(=0)R 52 ; C(=0)OR 53 ; or C(=0)NR 53 R 56 ; R 48 is C-_ * _-C_ι alkyl; C 2 -C 4 alkenyl; C 2 -C 4 halo¬ alkenyl; C 2 -C 4 alkynyl; or C 2 -C 6 alkoxyalkyl; R 49 is H; C J -C 4 alkyl; C 3 -C 4 alkenyl; or cyclo¬ propyl; R 50 is H; C 1 -C 4 alkyl; C 3 -C 4 alkenyl; or C 3 -C 4 alkynyl; or R 49 and R 50 can be taken together to form -(CH 2 ) -; -(CH 2 ) 5 - or -CH 2 CH 2 OCH 2 CH 2 -; R 51 is 1-3 halogen; C 1 -C alkoxy; C 2 -C 4 haloalkoxy; C 2 -C 4 alkoxyalkoxy; C 1 -C 4 alkylthio; C 3 -C 4 alkenyloxy; C 3 -C 4 alkynyloxy; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; C 1 -C 4 alkyl; CJ-C^J haloalkyl; C 2 -C 4 alkenyl; or C -C 4 haloalkenyl; R 53 is H; C J -C 4 alkyl; C 3 -C 4 alkenyl; or C 3 -C 4 haloalkenyl; R 60 is C____-C 4 alkyl; C 1 -C 4 haloalkyl; C 2 -C alkenyl; C 2 -C 4 haloalkenyl; C(=0) (C 1 -C 4 alkyl); or C(=0)H; R 6 2 i s c(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; 0C(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C( ^R^- OC^OOR 53 ; OC(=0)NR 53 R 56 ; or N(R 56 ) C(=0)OR 53 ; R 63 is H; C___-C 4 alkyl; C 3 -C 4 alkenyl; C 3 -C 4 alkynyl; C 3 -C 4 haloalkenyl; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; or OR 53 ; R 64 is C____-C 4 alkyl; or C 3 -C 4 alkenyl; R 65 is C 1 -C alkyl; C 3 -C 4 haloalkyl; or C 3 -C 4 alkenyl; and R 67 is H or C____-C 4 alkyl; provided that when R 3 is a phenyl or heterocyclic ring disubstituted with two alkyl or alkoxy groups, or one alkyl and one alkoxy group, then at least one of the alkyl and alkoxy groups is methyl or methoxy. 3. A compound of Claim 2 wherein: A is O or NH; B is halogen; cyano; R 21 ; OR 29 ; NR 49 R 63 ; N=CR 45 R 46 ; SR 47 ; or S(0) 2 R 48 ; R 1 is C___-C alkyl; C j -C ^j haloalkyl; or vinyl; R 2 is C -C 20 alkyl; C 2 -C 0 alkoxyalkyl; C -C 20 haloalkyl; C 3 -C 8 alkyl substituted with phenoxy or phenylthio each optionally substituted with R 30 ; C 5 -C 7 cycloalkyl; C 2 _C 20 alkenyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; provided that when R 2 is phenyl and R 5 is other than F, then R 5 is attached to the para- position relative to the imidazolinone ring; R 3 _is phenyl optionally substituted with R 10 ; R 44 is 1-3 halogen; C 1 -C alkoxy or C___-C 4 haloalkoxy; R 45 is H or C___-C 4 alkyl; R 46 is H; C J -C 4 alkyl; OR 65 ; or SR 65 ; R 47 is C___-C 4 alkyl; C 3 -C 4 alkenyl; C(=0)R 52 ; or C(=0)0R 55 ; R 48 is C -C 4 alkyl; R 51 is 1-3 halogen or C 2 -C 3 haloalkoxy; R 52 and R 53 are each independently H; C___-C 4 alkyl; or C 3 -C 4 alkenyl; R 60 and R 63 are each independently C 1 -C alkyl; and R 65 is C___-C alkyl or C 3 -C 4 alkenyl. 4. A compound of Claim 3 wherein: B is halogen; cyano; C 1 -C 4 alkyl, C___-C alkylthio, or C___-C alkoxy each optionally substituted with halogen; N=CR 45 R 46 ; NR 49 R 63 ; or S(0) 2 (C___-C 4 alkyl) ; R 1 is methyl or halomethyl; R 2 is C 2 -C 12 alkyl; C 3 -C 8 alkyl substituted with phenoxy optionally substituted with R 30 ; phenyl optionally substituted with R 5 and R 7; thienyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; R 3 is phenyl optionally substituted with F; Cl; or methyl; R 4 is H; R 5 is halogen; nitro; C___-Cg alkyl; -^-C^ haloalkyl; methylthio; C 1 -C 6 alkoxy; C___-C 2 haloalkoxy; C 5 -Cg cycloalkyloxy; phenoxy optionally substituted with R 27 ; phenylthio substituted with R 24 ; phenoxy ethyl optionally substituted with R 24 on the phenyl ring; benzyloxy optionally substituted with R 30 on the phenyl ring; or -0C(=0)R 28 ; R 7 and R 24 are independently F; C___-C 2 alkyl; methylthio; or C 1 -C 2 alkoxy; R 16 is Ci-Cg alkyl; R 19 is phenyl optionally substituted with R 34 ; R 27 is 1-2 halogen; cyano; C^^ alkyl; trifluoro¬ methyl; C j -0 4 alkoxy; C 1 -C 4 haloalkoxy; -^-d alkylthio; C 5 -C 6 cycloalkyloxy; or allyl; R 30 is 1-2 halogen; cyano; C 1 -C 4 alkyl; trifluoro¬ methyl; C 1 -C alkoxy; or trifluoromethoxy; R 34 is 1-2 halogen; nitro; C___-C 2 alkyl; or C 1 -C 2 alkoxy; R 46 is H or C ]. -^ alkyl; R 49 and R 63 are each independently C___-C alkyl. 5. A compound of Claim 4 wherein: B is F; Cl; cyano; C 1 -C alkyl; C 1 -C alkylthio; C 1 -C 2 alkoxy; N=CR 45 R 46 ; NMe 2 ; or S(0) 2 (C 1 -C 2 alkyl); R 1 is methyl; R 2 is C 1 -C 1 alkyl; phenyl optionally substituted with R 5 and R 7 ; or thienyl optionally substituted with R 5 and R 7 ; and R 5 is F; Cl; Br; C^Cg alkyl; trifluoromethyl; C j^ -C alkoxy; trifluoromethoxy; 2, 2, 2-trifluoro- ethoxy; C 5 -Cg cycloalkyloxy; methylthio; phenoxy optionally substituted with R 27 ; phenylthio optionally substituted with R 24 ; benzyloxy optionally substituted with R 30 on the phenyl ring; or -OC(=0)R 28 . 6. A compound of Claim 5 which is: 3, 5-dihydro-2-methoxy-5-methyl-5-phenyl-3- (phenylamino) -4H-imidazol-4-one; or 3, 5-dihydro-5-methyl-2- (methylthio)-5-phenyl-3- (phenylamino) -4H-imidazol-4-one. 7. A fungicidal composition comprising an effective amount of a compound of Formula I wherein: A is O; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P(=0) (C 1 -C 4 alkyl) 2 ; or OG; G is H; C j -Cg alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C(=0) (C___-C 4 alkyl); C(=0) (C 1 -C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 21 . OR 29 ; NR 9 R 63 ; N=CR 45 R 46 ; SR 47 ; S(0) n R 48 ; or S0 2 NR 49 R 60 ; n is 1 or 2; R 1 is C 1 -C 4 alkyl; C 1 -C 4 haloalkyl; C 3 -C 6 cyclo- alkyl; C -C alkenyl; C 2 -C alkoxycarbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is C___-C 20 alkyl optionally substituted with R 22 ; C -C 0 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 OCH 2 CH 2 ) CH-; (CH 2 CH 2 SCH 2 CH 2 ) CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; fur l optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of -CH 2 (CH 2 ) 2 CH 2 _ , —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH 2 ) 4 CH 2 —, "CH CH 2 OCH 2 CH 2 _ , —CH 2 CH SCH 2 CH 2 —, R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenyl¬ methyl; R 4 is H or methyl; R 5 is halogen; nitro; cyano; C___-C 6 alkyl; C 5 -C 6 cycloalkyl; C___-C 6 haloalkyl; C j -Cg alkylthio; C___-Cg haloalkylthio; Cj-Cg alkoxy; C___-Cg haloalkoxy; C 5 -Cg cycloalkyloxy; C 2 _Cg alkoxyalkyl; C 2 -Cg alkoxyalkoxy; C 3 -C 6 alkenyl; C 3 -Cg haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -Cg alkynyl; C 3 _C 6 haloalkynyl; C 3 -C 6 alkynyloxy; alkylsulfonyl; C j -Cg haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxy- methyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC(=0)NHR 28 ; -C(=0)OR 28 ; or -0C(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; C j -C . ^ alkyl; trifluoro¬ methyl; methylthio; or C___-C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or C___-C 4 alkyl; R 9 is C 1 -C 18 alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C 1 _C 4 alkyl, tri¬ fluoromethyl, C 1 -C 4 alkylthio, C 1 -C 4 alkoxy and trifluoromethoxy; R 11 and R 36 are independently C 1 -C 6 alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; C J -C3 alkyl optionally substituted with C 1 -C 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; C j -C^ alkyl optionally substituted with R 31 ; C 2 -C 17 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 4 -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C 2 -C 5 alkoxycarbonyl; R 17 and R 18 are independently C 1 -C 18 alkyl optionally substituted with R 23 ; C 2 -C 10 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; C 3 -C 12 cycloalkyl; C 5 -Cg cycloalkenyl; Cg-C 7 alkylcycloalkyl; Cg-C 7 cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; CJ-CJ Q alkyl; C 5 -C 6 cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH 2 ~, —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH 2 ) CH 2 —, -CH 2 CH 2 OCH 2 CH 2 -, -CH 2 CH(Me) CH 2 CH(Me) CH 2 -, and -CH 2 CH(Me)OCH(Me)CH 2 -; R 21 is C j -Cs alkyl optionally substituted with R 51 ; C 2 -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)SR 53 ; C(=NR 55 )OR 53 ; C(=S)SR 53 ; C(=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is 0; NR 55 ; or a direct bond; R 22 is cyano; nitro; C^ ^ -C j g alkylthio; C___-C 19 alkyl- sulfinyl; C j -C^ haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; _ l -c l9 alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 8 R 40 NC(=O)O; R 39 R 40 N; (C___-C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -Cg cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is O or S; Q is 0 or N-T-W; T is O; NR 37 ; or a direct bond; is H; C___-C 8 alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)OR 28 ; or C(=0)NR 28 R 14 ; R 23 is 1-3 halogen; C 1 -C 12 alkoxy; C 1 -C 1 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; C_ j ,-Cg alkyl; C___-Cg haloalkyl; C j^ -C alkoxy; Ci-Cg haloalkoxy; C___-C4 alkylsulfonyl; C 2 -C 6 alkoxyalkyl; C___-C alkyl¬ thio; C 5 -C 6 cycloalkyl; C 5 -C 6 cycloalkyloxy; c 2 -c 6 alkenyl; C 2 -C 6 haloalkenyl; C 2 -Cg alkynyl; hydroxycarbonyl; C-2-C^ alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is C j^ -C β alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is C____-C 8 alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -Cg alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[-N(C 1 -C alkyl) ]OR 53 ; C (=0) NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C___-C alkyl, trifluoromethyl, C-^-C^ alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; C 1 -C 18 alkoxy; allyloxy; C 1 -C 18 alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C 2 -C 5 alkoxy¬ carbonyl; R 32 is 1-3 halogen; or C 1 -C alkoxy; R 35 is cyano; nitro; C____-C 17 alkylthio; C____-C____ 7 alkyl¬ sulfinyl; C____-C 17 haloalkoxy; C 5 -C 6 cycloalkyl- oxy; C 2 -C 17 haloalkenyl; C 3 -C 17 alkenyloxy; C -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C___-C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 40 R 39 N; (C 1 -C alkoxy) 2 P (=E) O; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl¬ thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; C___-C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 _C 17 haloalkoxy- alkoxy; R 37 is H; Ci-Cg alkyl; or phenyl optionally substituted with R 7 ; R 39 is Ci-C 19 alkyl; C -C 19 alkylcarbonyl; C 2 -C 19 alkoxycarbonyl; (R 9 R 40 N)C=O; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; C^C^ alkylthio; C^C^ alkylsulfinyl; C 1 -C 17 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; C____-C____ 7 alkylsulfonyl; C -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)0; R 0 R 39 N; (C 1 -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N+; phenyl, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; C___-C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; R 42 is cyano; nitro; C___-C 17 alkylthio; C___-C 17 alkylsulfinyl; C___-C 17 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C____C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 0 NC(=O)O; R 40 R 39 N; (C 1 -C 4 alkoxy) 2 P (=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra¬ hydropyranyl; 2-tetrahydropyranyloxy; C 1 -C 17 alkoxy; 1-3 halogen; C _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; C j^ -Cg alkoxy; C j^ -C haloalkoxy; C 2 -Cg alkoxyalkoxy; C 1 -C 6 alkylthio; C___-Cg alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 49 R 50 ; or R 62 ; R 45 is H; C___-C 4 alkyl; Cι-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 5 R 55 ; or SR 54 ; R 46 is H; Ci-C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is Ci-Cg alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(C 1 -C 4 alkyl) ]OR 53 ; or C(=0)NR 53 R 56 ; R 48 is Ci-Cg alkyl; C 2 -C 6 alkenyl; C 2 -C 6 halo¬ alkenyl; C -Cg alkynyl; C 2 -Cg alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; Ci~C 4 alkyl; C 3 -C 4 alkenyl; or cyclo¬ propyl; R 50 is H; Ci-Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; c 2~ c 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH 2 ) -; -(CH 2 ) 5 - or -CH 2 CH 2 OCH 2 CH 2 -; R 51 is 1-3 halogen; Ci-C 6 alkoxy; C 2 -C 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; C^C alkylthio; C -C haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl¬ oxy; C ~C alkylsulfonyl; C^Cg haloalkyl- sulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; Cι-C 4 alkyl; C -C 4 haloalkyl; C 2 -C 4 alkenyl; C -Cg haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci~Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -Cg alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or C -C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or C -C 4 alkyl; R 60 is Cι-C 4 alkyl; Cι~C 4 haloalkyl; C 2 -C alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; Ci-C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C -Cg haloalkenyl; or phenyl optionally substituted with R 57 ; R 62 i s C ( =N _V-R53) R 52. c(=0)OR 53 ; C(=0)NR 53 R 56 ; C(=NR 55 )OR 53 ; C(=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC(=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC(=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N(R 56 ) C(=0)OR 53 ; or N(R 56 )C(=NR 55 )NR 53 R 54 ; R 63 is H; C 1 -C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; c 2 _c 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C (=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is Ci~C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently Ci~C alkyl; C 3 -C 4 haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; Ci~C 4 alkyl; Ci~C 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; Ci-C 4 alkyl; Ci-C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20; and at least one of (a) a surfactant, (b) an organic solvent, and (c) at least one solid or liquid diluent. 8. A method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof to be protected, or to the plant seed or seedling to be protected, an effective amount of a compound of Formula I wherein: A is 0; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P(=0) (Cι-C 4 alkyl) 2 ; or OG; G is H; C i ~C alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C(=0) (Cι-C 4 alkyl); C(=0) (C 1 -C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 21 ; OR 29 ; NR 49 R 63 ; N=CR 45 R 46 ; SR 47 ; S(0) n R 48 ; or S0 2 NR 49 R 60 ; n is 1 or 2; R 1 is C χ -C 4 alkyl; Ci~C haloalkyl; C 3 -C 6 cycloalkyl; C 2 -C alkenyl; C 2 -C alkoxy¬ carbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is Ci~C 20 alkyl optionally substituted with R 22 ; C 2 -C 20 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 OCH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 )CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH ~, —CH 2 (CH 2 ) CH 2 —, —CH (CH 2 ) 4 CH 2 —, —CH 2 CH 2 OCH 2 CH _ , —CH 2 CH 2 SCH 2 CH 2 —, R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenylmethyl; R 4 is H or methyl; R 5 is halogen; nitro; cyano; C^Cg alkyl; C 5 -Cg cycloalkyl; Ci-Cg haloalkyl; C ~C alkylthio; Ci-Cg haloalkylthio; Ci~C alkoxy; Cι~Cg haloalkoxy; C 5 -C 6 cycloalkyloxy; C 2 _C 6 alkoxyalkyl; C 2 -Cg alkoxyalkoxy; C 3 -C 6 alkenyl; C -Cg haloalkenyl; C 3 -Cg alkenyloxy; C 3 -Cg alkynyl; C 3 _C 6 haloalkynyl; C 3 -C 6 alkynyloxy; Ci~Cg alkylsulfonyl; C 1 -Cg haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxymethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC(=0)NHR 28 ; -C(=0)OR 28 ; or -OC(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; Ci~C alkyl; trifluoro¬ methyl; methylthio; or Ci-C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or C_ -c 4 alkyl; R 9 is Ci~Cι 8 alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci_C 4 alkyl, trifluoromethyl, Ci-C 4 alkylthio, Ci-C 4 alkoxy and trifluoromethoxy; R 11 and R 36 are independently C^-Cg alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; Cι~C 8 alkyl optionally substituted with c l ~ c 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; c 3 _c 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; C -Cι 7 alkyl optionally substituted with R 31 ; C 2 -C 17 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; C 6 -C 7 alkylcycloalkyl; C 4 -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C -C 5 alkoxycarbonyl; R 17 and R 18 are independently Cι-C 18 alkyl optionally substituted with R 23 ; C -Cι 0 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; C 3 -C 12 cycloalkyl; C 5 -C 6 cycloalkenyl; Cg-C 7 alkylcycloalkyl; Cg-C 7 cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; Ci-Cι 0 alkyl; C 5 -Cg cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH 2 (CH ) 2 CH 2 ~, —CH 2 (CH 2 ) CH 2 —, —CH (CH ) 4 CH —, -CH 2 CH 2 OCH 2 CH 2 -, -CH 2 CH(Me)CH 2 CH(Me)CH 2 ~, and -CH 2 CH(Me)OCH(Me)CH 2 ~; R 21 is Ci~C 8 alkyl optionally substituted with R 51 ; C -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)SR 53 ; C(=NR 55 )OR 53 ; C(=S)SR 53 ; C(=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is 0; NR 55 ; or a direct bond; R 22 is cyano; nitro; C -C 19 alkylthio; Cι-C 19 alkyl- sulfinyl; Ci-C 19 haloalkoxy; C 5 -C 6 cyclo¬ alkyloxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; Cι~C 19 alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 39 R 0 N; (Cι~C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 1 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -C 6 cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is 0 or S; Q is O or N-T- ; T is O; NR 37 ; or a direct bond; is H; Ci~C 8 alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)OR 28 ; or C(=0)NR 28 R 14 ; R 23 is 1-3 halogen; Ci-C 12 alkoxy; C -C 1 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; C^C alkyl; Cι-C 6 haloalkyl; C -Cg alkoxy; Ci-Cg haloalkoxy; Cι~C 4 alkylsulfonyl; C 2 -Cg alkoxyalkyl; Ci-C 4 alkyl¬ thio; C 5 -Cg cycloalkyl; C 5 -C 6 cycloalkyloxy; c 2 ~ c 6 alkenyl; C 2 -C 6 haloalkenyl; C 2 -C 6 alkynyl; hydroxycarbonyl; C -C 4 alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is Ci~C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is Ci~C 8 alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -Cg alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(_i-C 4 alkyl) ]OR 53 ; C(=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci-C 4 alkyl, trifluoromethyl, Ci-C alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; Ci-C 18 alkoxy; allyloxy; Ci-C 18 alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C 2 -C 5 alkoxy¬ carbonyl; R 32 is 1-3 halogen; or Cι-C 4 alkoxy; R 35 is cyano; nitro; Ci-C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci-C 17 haloalkoxy; C 5 -C 6 cycloalkyl- oxy; C 2 -C 17 haloalkenyl; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; Cι-C 17 alkylsulfonyl; C -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 40 R 39 N; (Cι-C 4 alkoxy) 2 P (=E)O; R 1:L S0 3 ; R 40 R 1 R 38 N + ; phenyl, phenoxy, phenyl¬ thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra- hydropyranyl; 2-tetrahydropyranyloxy; Ci~C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C _Cι 7 haloalkoxyalkoxy; R 37 is H; Ci-C alkyl; or phenyl optionally substituted with R 7 ; R 39 is C 1 -C 19 alkyl; C 2 -Cι 9 alkylcarbonyl; C 2 -Cι 9 alkoxycarbonyl; (R 9 R 0 N)C=O; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; Ci-C 17 alkylthio; Cι-C 17 alkylsulfinyl; Ci-C 17 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; Ci-C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 0 NC(=0)O; R 40 R 39 N; (Cι-C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; R 42 is cyano; nitro; Ci-C 17 alkylthio; C -Cι 7 alkyl- sulfinyl; C -C 17 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; Ci_C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)0; R 40 R 39 N; (C 1 -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; Ci~Cg alkoxy; c ι~ c 6 haloalkoxy; C -C 6 alkoxyalkoxy; C ~Cg alkylthio; Ci~Cg alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 49 R 50 ; or R 62 ; R 45 is H; Cι-C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 54 R 55 ; or SR 54 ; R 46 is H; C 1 -C 4 alkyl; C 1 -C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is Ci-C 8 alkyl optionally substituted with R 44 ; c 3 ~ c 6 alkenyl or C 3 -Cg alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(C 1 -C 4 alkyl) ]0R 53 ; or C(=0)NR 53 R 56 ; R 48 is Ci-C 6 alkyl; C 2 -C 6 alkenyl; C 2 -C 6 halo¬ alkenyl; C 2 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; Ci~C 4 alkyl; C 3 -C 4 alkenyl; or cyclo¬ propyl; R 50 is H; Ci-Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH 2 ) -; -(CH 2 ) 5 - or -CH 2 CH 2 OCH 2 CH 2 -; R 51 is 1-3 halogen; Cι~Cg alkoxy; C -C 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; Ci~Cg alkylthio; Ci-Cg haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl¬ oxy; C i ~Cg alkylsulfonyl; Cι~Cg haloalkyl- sulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; Ci-C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -Cg alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or Ci-C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or Ci-C alkyl; R 60 is Cι-C 4 alkyl; Ci-C haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; C 1 -C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 62 is C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; C(=NR 55 )OR 53 ; C(=NR 55 )NR 53 R 56 ; 0C(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC(=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC(=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N(R 56 )C(=0)OR 53 ; or N(R 56 ) C (=NR 55 )NR 53 R 54 ; R 63 is H; C 1 -Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; c 2~ c 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is Ci-C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently Ci-C alkyl; C 3 -C 4 haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; C -C 4 alkyl; Cι-C 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -Cg haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; Ci-C 4 alkyl; C -C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20. 9. A method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof to be protected, or to the plant seed or seedling to be protected, an effective amount of a composition of Claim 7. AMENDED CLAIMS [received by the International Bureau on 18 October 1993 (18.10.93); original claims unchanged; new claims 10-18 added (27 pages) N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC (=0)NR 53 R 56 ; 0C(=S)SR 53 ; SC(=0)0R 53 ; N (R 56 ) C (=0)OR 53 ; or N(R 56 ) C (=NR 55 )NR 53 R 54 ; R 63 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; c 2 _c 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C(=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is Ci-C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently C ~C alkyl; C 3 -C haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; Ci-C 4 alkyl; Ci~C 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; Ci~C 4 alkyl; Ci~C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20. 9. A method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof to be protected, or to the plant seed or seedling to be protected, an effective amount of a composition of Claim 7. 10. A fungicidal composition comprising an effective amount of a compound of Formula I wherein: A is O; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P(=0) (Ci-C 4 alkyl) 2 ; or OG; G is H; Ci~C alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C (=0) (Ci-C 4 alkyl); C(=0) (Ci-C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 21 . OR 29 ; NR 9 R 63 ; N=CR 45 R 46 ; SR 47 ; S(0) n R 48 ; or S0 2 NR 9 R 60 ; n is 1 or 2; R 1 is Ci~C 4 alkyl; Ci~C 4 haloalkyl; C 3 -C 6 cycloalkyl; C -C 4 alkenyl; C 2 -C alkoxy¬ carbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is C -C 20 alkyl optionally substituted with R 22 ; C 2 -C 2Q alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 OCH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 )CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH ~, —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH ) CH 2 —, —CH 2 CH 2 OCH 2 CH 2 _ , —CH CH 2 SCH 2 CH 2 _ , R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenyl¬ methyl; R 4 is H or methyl; R 5 is halogen; nitro; cyano; C^C alkyl; C 5 -Cg cycloalkyl; Ci-Cg haloalkyl; Ci-C alkylthio; C 1 -Cg haloalkylthio; C^C alkoxy; Ci~Cg halo¬ alkoxy; C 5 -Cg cycloalkyloxy; C 2 _C 6 alkoxyalkyl; C 2 -C 6 alkoxyalkoxy; C 3 -C 6 alkenyl; C 3 -Cg haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl; C 3 _Cg haloalkynyl; C 3 -C 6 alkynyloxy; C^C alkylsulfonyl; Ci~C haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxymethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC(=0)NHR 28 ; -C(=0)OR 28 ; or -OC(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; C i ~C 4 alkyl; trifluoro¬ methyl; methylthio; or Ci~C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or C x -C 4 alkyl; R 9 is C 1 -C 18 alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci_C 4 alkyl, trifluoromethyl, C -C 4 alkylthio, Ci-C alkoxy and trifluoromethoxy; R 11 and R 36 are independently Ci-C 6 alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; C -C 8 alkyl optionally substituted with C -C 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; Ci-C 17 alkyl optionally substituted with R 31 ; C 2 -C 17 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; Cg-C 7 alkylcycloalkyl; C -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C 2 -C 5 alkoxycarbonyl; R 17 and R 18 are independently Ci-Cι 8 alkyl optionally substituted with R 23 ; C 2 -C 10 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; C 3 -C 12 cycloalkyl; C 5 -C 6 cycloalkenyl; Cg-C 7 alkylcycloalkyl; Cg-C cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; Ci-C 10 alkyl; C 5 -C 6 cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH (CH 2 ) 2 CH 2 _ , —CH 2 (CH 2 ) 3 CH —, —CH 2 (CH 2 ) 4 CH 2 ~, -CH 2 CH 2 OCH 2 CH 2 -, -CH 2 CH(Me)CH 2 CH(Me)CH 2 -, and -CH 2 CH(Me)OCH(Me)CH 2 ~; R 21 is Ci~C 8 alkyl optionally substituted with R 51 ; C 2 -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C (=0) SR 53 ; C(=NR 55 )0R 53 ; C(=S)SR 53 ; C (=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is 0; NR 55 ; or a direct bond; R 22 is cyano; nitro; Ci-C 19 alkylthio; Ci-C 19 alkyl¬ sulfinyl; Ci-C 19 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; C l ~Ci 9 alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 39 R 40 N; (C 1 -C alkoxy) 2 P(=E)0; R ι:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl- sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -C 6 cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is O or S; Q is O or N-T- ; T is 0; NR 37 ; or a direct bond; W is H; Ci~C 8 alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)0R 28 ; or C (=0)NR 28 R 14 ; R 23 is 1-3 halogen; Ci-C 12 alkoxy; Ci-C 12 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; Ci~C alkyl; Ci~C haloalkyl; C^Cg alkoxy; C- j^ -C haloalkoxy; Ci~C 4 alkylsulfonyl; C 2 -C 6 alkoxyalkyl; Ci~C 4 alkyl¬ thio; C 5 -Cg cycloalkyl; C 5 -Cg cycloalkyloxy; C 2 -Cg alkenyl; C 2 -C 6 haloalkenyl; C 2 -C 6 alkynyl; hydroxycarbonyl; C 2 -C alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is Ci-C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is C ~C 8 alkyl optionally substituted with R 44 ; C 3 -C 6 alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C[= (C 1 -C 4 alkyl) ]OR 53 ; C(=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C ~C alkyl, trifluoromethyl, Ci~C 4 alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; Ci~C 18 alkoxy; allyloxy; C ~Cι 8 alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C 2 -C 5 alkoxy¬ carbonyl; R 32 is 1-3 halogen; or C ~C 4 alkoxy; R 35 is cyano; nitro; C -C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci~C 17 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 2 -C 17 haloalkenyl; C 3 -C 1 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C 1 -C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)0; R 40 R 39 N; (C_ι_-C 4 alkoxy) 2 P (=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra¬ hydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 _Cι 7 haloalkoxyalkoxy; R 37 is H; Ci-C alkyl; or phenyl optionally substituted with R 7 ; R 39 is Ci-C 19 alkyl; C 2 -C 19 alkylcarbonyl; C 2 -C 19 alkoxycarbonyl; (R 9 R 40 N)C=O; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; Ci-C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci-C 17 haloalkoxy; C 5 -C 6 cycloalkyl- oxy; C 3 -C 17 alkenyloxy; C -C 17 alkynyloxy; c ι -c i 7 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 0 R 39 N; (C 1 -C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; ? 42 is cyano; nitro; Ci-C 17 alkylthio; C -C 17 alkyl¬ sulfinyl; C -C 17 haloalkoxy; C 5 -C 6 cyclo- alkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; Ci_C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C ( =0)0; R28 0 C(=0)0; R 28 R 0 NC(=O)O; R 0 R 39 N; (C 1 -C alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N + ; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; C^Cg alkoxy; c ι~ c 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; Ci~Cg alkylthio; C -C 6 alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 9 R 50 ; or R 62 ; R 45 is H; C 1 -C 4 alkyl; Cι-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 54 R 55 ; or SR 54 ; R 46 is H; Ci-C 4 alkyl; C -C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -Cg haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is Ci~C 8 alkyl optionally substituted with R 44 ; c 3~ c 6 alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)0R 53 ; C[«N(C 1 -C 4 alkyl)]OR 53 ; or C (=0)NR 53 R 56 ; R 48 is Ci-C alkyl; C 2 -C 6 alkenyl; C -C 6 halo¬ alkenyl; C 2 -Cg alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; Cι-C 4 alkyl; C 3 -C 4 alkenyl; or cyclopropyl; R 50 is H; C 1 -C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH 2 ) 4 -; -(CH 2 ) 5 - or -CH 2 CH 2 OCH 2 CH 2 -; R 51 is 1-3 halogen; Ci~C alkoxy; C 2 -C 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; Ci-C 6 alkylthio; C ~Cg haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl¬ oxy; C -Cg alkylsulfonyl; Ci-C 6 haloalkyl- sulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; C -C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci-Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or Ci~C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or Ci-C 4 alkyl; R 60 is Cι-C 4 alkyl; Ci~C 4 haloalkyl; C 2 -C 4 alkenyl; C -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; Ci~C 4 alkyl; Cι-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 62 is C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C (=0)NR 53 R 56 ; C(=NR 55 )0R 53 ; C (=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC (=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC (=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N (R 56 ) C (=0)OR 53 ; or N(R 56 )C (=NR 55 )NR 53 R 54 ; R 63 is H; Ci-Cg alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C -C 6 alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C (=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is Ci~C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently C ~C 4 alkyl; c 3 _c 4 haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; Ci~C 4 alkyl; Ci-C 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; Ci~C 4 alkyl; Ci~C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20; at least one additional fungicidal compound; and at least one of (a) a surfactant, (b) an organic solvent, and (c) at least one solid or liquid diluent. 11. A composition of Claim 10 wherein the additional fungicidal compound is selected from the group consisting of maneb, cymoxanil, fenpropidine, fenpropimorph, phosethyl-Al, metalaxyl, oxadixyl, tebuconazole, difenoconazole, diniconazole, fluquinoxonazole, ipconazole, metconazole, penconazole, propiconazole, uniconzole, copper oxychloride, furalaxyl, folpet, flusilazol, probenazole, tricyclazole, and flutriafol. 12. A composition of Claim 11 wherein the compound of Formula I is 3, 5-dihydro-2-methoxy-5-methyl-5- phenyl-3- (phenylamino) -4H-imidazol-4-one; or 3, 5-dihydro-5-methyl-2- (methylthio) -5-phenyl-3- (phenyl¬ amino) -4H-imidazol-4-one. 13. A composition of Claim 12 wherein the compound of Formula I is 3, 5-dihydro-5-methyl-2- (methylthio) -5- phenyl-3- (phenylamino)-4H-imidazol-4-one and the additional fungicidal compound is cymoxanil. 14. A method for controlling plant diseases comprising applying to the plant or portion thereof to be protected, or to the plant seed or seedling to be protected an effective amount of fungicidal composition comprising a compound of Formula I wherein: A is 0; S or N-J; J is R 15 ; C(=0)R 16 ; C(=0)OR 17 ; C(=0)SR 18 ; C(=0)NR 19 R 20 ; P(=0) (C 1 -C 4 alkyl) 2 ; or OG; G is H; C ~C alkyl; benzyl optionally substituted with R 34 on the phenyl ring; C(=0) (Ci-C 4 alkyl); C(«0) (C 1 -C 4 alkoxy); or C(=0)NHR 36 ; B is H; halogen; cyano; NC; S=C=N; 0=C=N; nitro; R 21 ; OR 29 ; NR 49 R 63 ; N=CR 5 R 46 ; SR 47 ; S (0) n R 48 ; or S0 2 NR 49 R 60 ; n is 1 or 2 ; R 1 is C -C 4 alkyl; Cι-C 4 haloalkyl; C 3 -C 6 cycloalkyl; C 2 -C 4 alkenyl; C 2 -C 4 alkoxy¬ carbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is Ci-C 20 alkyl optionally substituted with R 22 ; C 2 -C 20 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 OCH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 )CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH _ , —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH 2 ) 4 CH 2 —, —CH 2 CH OCH 2 CH 2 ~, —CH 2 CH 2 SCH 2 CH 2 ~, R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenyl¬ methyl; R 4 is H or methyl; R 5 is halogen; nitro; cyano; Cι~C 6 alkyl; C 5 -Cg cycloalkyl; C ~Cg haloalkyl; C^Cg alkylthio; Ci-C haloalkylthio; Ci~C 6 alkoxy; ^-Cg halo¬ alkoxy; C 5 -Cg cycloalkyloxy; C 2 _C 6 alkoxyalkyl; c 2 -c 6 alkoxyalkoxy; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -Cg alkynyl; C 3 _C 6 haloalkynyl; C 3 -C 6 alkynyloxy; Ci~Cg alkylsulfonyl; Ci~C haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxymethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC (=0)NHR 28 ; -C(=0)OR 28 ; or -OC(=0)R 28 ; R 6 , R 7 , R 12 , R 13 , R 24 , R 26 and R 34 are independently 1-2 halogen; nitro; Ci~C 4 alkyl; trifluoro¬ methyl; methylthio; or C ~C 4 alkoxy; R 8 , R 14 , R 20 , R 38 and R 40 are independently H or C 1 -C 4 alkyl; R 9 is Ci-C 18 alkyl; or phenyl optionally substituted with R 7 ; R 10 , R 25 and R 33 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci_C 4 alkyl, trifluoromethyl, Ci~C 4 alkylthio, Ci~C 4 alkoxy and trifluoromethoxy; R 11 and R 36 are independently C-^Cg alkyl; or phenyl optionally substituted with R 12 ; R 15 is H; Cι~C 8 alkyl optionally substituted with C i ~C 2 alkoxy; C 3 -C 6 cycloalkyl; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; phenyl optionally substituted with R 13 ; benzyl optionally substituted with R 13 on the phenyl ring and with R 20 on the benzylic carbon; or pyridyl optionally substituted with R 13 ; R 16 is H; Ci-C 17 alkyl optionally substituted with R 31 ; C 2 -C 1 alkenyl optionally substituted with R 32 ; C 2 -C 7 alkynyl; C 3 -C 8 cycloalkyl; C 5 -C 6 cycloalkenyl; Cg-C 7 alkylcycloalkyl; C 4 -C 8 cycloalkylalkyl; phenyl optionally substituted with R 33 ; naphthalenyl, furanyl, thienyl, benzoyl, or pyridyl each optionally substituted with R 34 ; or C 2 -C 5 alkoxycarbonyl; R 17 and R 18 are independently C -C 18 alkyl optionally substituted with R 23 ; C -C 10 alkenyl optionally substituted with R 32 ; C 3 -C 8 alkynyl; C 3 -Cι 2 cycloalkyl; C 5 -Cg cycloalkenyl; Cg-C 7 alkylcycloalkyl; Cg-C cycloalkylalkyl; or phenyl, naphthalenyl, or thienyl each optionally substituted with R 34 ; R 19 is H; C -Cio alkyl; C 5 -C 6 cycloalkyl; or phenyl optionally substituted with R 34 ; or R 19 and R 20 can be taken together to form a structure selected from the group consisting of —CH (CH ) 2 CH 2 _ , —CH 2 (CH 2 ) 3 CH 2 —, —CH 2 (CH 2 ) 4 CH 2 —, -CH 2 CH 2 0CH 2 CH 2 -, -CH 2 CH(Me)CH 2 CH(Me)CH 2 -, and -CH 2 CH(Me)OCH (Me) CH 2 -; R 21 is Ci~C 8 alkyl optionally substituted with R 51 ; C 2 -C 8 alkenyl or C 2 -C 8 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C(=0)SR 53 ; C(=NR 55 )0R 53 ; C(=S)SR 53 ; C(=0)NR 53 R 56 ; or C(=NR 55 )NR 53 R 56 ; V is O; NR 55 ; or a direct bond; R 22 is cyano; nitro; C -C 19 alkylthio; C ~C 19 alkyl¬ sulfinyl; C -C 19 haloalkoxy; C 5 -Cg cycloalkyl- oxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; C -C 19 alkylsulfonyl; C -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 0C(=0)0; R 28 R 40 NC(=O)O; R 39 R 40 N; (Ci-C 4 alkoxy) 2 P (=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl¬ sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -Cg cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; E is 0 or S; Q is 0 or N-T-W; T is O; NR 37 ; or a direct bond; is H; Ci-C 8 alkyl, C 3 -C 8 alkenyl; phenylmethyl optionally substituted with R 7 on the phenyl ring and R 14 on the benzylic carbon; phenyl or pyridyl each optionally substituted with R 7 ; C(=0)R 28 ; C(=0)OR 28 ; or C (=0)NR 28 R 14 ; R 23 is 1-3 halogen; Ci-C 12 alkoxy; C 1 -Cι 2 alkylthio; phenyl or naphthalenyl each optionally substituted with R 34 ; or phenoxymethyl optionally substituted with R 34 on the phenyl ring; R 27 is 1-2 halogen; nitro; cyano; Ci~Cg alkyl; Ci~Cg haloalkyl; C^C alkoxy; C ~C haloalkoxy; C -C 4 alkylsulfonyl; C 2 -Cg alkoxyalkyl; Ci~C 4 alkyl¬ thio; C 5 -Cg cycloalkyl; C 5 -C 6 cycloalkyloxy; C 2 -C 6 alkenyl; C 2 -C 6 haloalkenyl; C 2 -C 6 alkynyl; hydroxycarbonyl; C 2 -C alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is Ci-C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 29 is Ci-C 8 alkyl optionally substituted with R 44 ; c 3 -c 6 alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -Cg cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[-N(C 1 -C 4 alkyl) ]OR 53 ; C (=0)NR 53 R 56 ; N=CR 68 R 67 ; or S0 2 R 52 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci~C 4 alkyl, trifluoromethyl, Ci~C alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 31 is 1-3 halogen; Ci-C 18 alkoxy; allyloxy; Ci-C 18 alkylthio; phenyl, phenoxy, benzyloxy, or phenylthio each optionally substituted with R 34 on the phenyl ring; acetyl; or C 2 -C 5 alkoxy- carbonyl; R 32 is 1-3 halogen; or Ci~C 4 alkoxy; R 35 is cyano; nitro; Ci-C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; C -C 17 haloalkoxy; C 5 -Cg cycloalkyl¬ oxy; C 2 -C 17 haloalkenyl; C 3 -C 17 alkenyloxy; c 3 _c i 7 haloalkynyl; C 3 -C 17 alkynyloxy; Ci-C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 40 R 39 N; (Ci-C 4 alkoxy) 2 P (=E) 0; R 1:L S0 3 ; R 0 R 1 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra- hydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 _C 17 haloalkoxyalkoxy; R 37 is H; Ci-C alkyl; or phenyl optionally substituted with R 7 ; R 39 is Cι-C 19 alkyl; C 2 -C 19 alkylcarbonyl; C 2 -Cι 9 alkoxycarbonyl; (R 9 R 40 N)C=O; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; Ci-C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci-C 17 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; c l ~ c l7 alkylsulfonyl; C 2 -C 1 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 0C(=0)0; R 28 R 40 NC(=O)O; R 40 R 39 N; (C 1 -C 4 alkoxy) 2 P (=E)0; R 11 S0 3 ; R 40 R 1 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; R 42 is cyano; nitro; C -C 17 alkylthio; Cι-C 17 alkyl¬ sulfinyl; C -C 17 haloalkoxy; C 5 -Cg cyclo¬ alkyloxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C _C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)O; R 0 R 39 N; (Cι-C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 0 R 14 R 38 N + ; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; C -C 17 alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or c 3 ~ c 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; C^Cg alkoxy; C ~C haloalkoxy; C 2 -Cg alkoxyalkoxy; Ci~Cg alkylthio; Ci~C alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 49 R 50 ; or R 62 ; R 45 is H; C -C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; NR 54 R 55 ; or SR 54 ; R 46 is H; Ci~C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; NR 56 R 64 ; OR 65 ; or SR 65 ; R 47 is Ci~C 8 alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[=N(Ci-C 4 alkyl)]OR 53 ; or C (=0)NR 53 R 56 ; R 48 is Ci-C alkyl; C 2 -C 6 alkenyl; C 2 -C 6 halo¬ alkenyl; C 2 -C 6 alkynyl; C -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 ; or phenylmethyl optionally substituted with R 58 on the phenyl ring; R 49 is H; Ci~C 4 alkyl; C 3 -C 4 alkenyl; or cyclopropyl; R 50 is H; Ci-C 6 alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -Cg alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form -(CH 2 ) 4 -; -(CH 2 ) 5 - or -CH 2 CH 2 0CH 2 CH 2 -; R 51 is 1-3 halogen; Ci~C alkoxy; C 2 -C 6 haloalkoxy; C -C 6 alkoxyalkoxy; C^C alkylthio; Ci-C haloalkylthio; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl- oxy; C^C alkylsulfonyl; C -C haloalkyl- sulfonyl; phenylsulfonyl optionally substituted with R 57 ; phenyl or phenoxy each optionally substituted with R 58 and R 59 ; OH; SH; nitro; cyano; 0=C=N; S=C=N; NR 49 R 50 ; or R 62 ; R 52 is H; Ci-C 4 alkyl; Cι-C 4 haloalkyl; C 2 -C 4 alkenyl; C -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or C ~C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or Cι~C 4 alkyl; R 60 is Ci~C 4 alkyl; C____-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; or C(=0)R 61 ; R 61 is H; Ci-C 4 alkyl; Ci~C 4 haloalkyl; C 2 -C alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 62 is C(=N-V-R 53 )R 52 ; C(=0)OR 53 ; C (=0)NR 53 R 56 ; C(=NR 55 )0R 53 ; C(=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC (=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC (=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N (R 56 ) C (=0)OR 53 ; or N (R 56 ) C (=NR 55 )NR 53 R 54 ; R 63 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; C 3 -Cg haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C (=0)NR 53 R 56 ; OR 53 ; or S0 2 R 52 ; R 64 is Ci-C 4 alkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 65 and R 66 are each independently Ci-C 4 alkyl; C 3 -C haloalkyl; C 3 -C 6 alkenyl; or phenyl optionally substituted with R 57 and R 59 ; R 67 is H; C 1 -C 4 alkyl; Ci~C 4 haloalkyl; or C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; phenyl optionally substituted with R 57 ; OR 66 ; SR 66 ; or NR 54 R 66 ; R 68 is H; Ci~C 4 alkyl; Cι~C 4 haloalkyl; or C 2 -C 4 alkenyl; and R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; provided that the total number of carbons in R 2 , R 16 , R 17 and R 18 is each less than or equal to 20; at least one additional fungicidal compound; and at least one of (a) a surfactant, (b) an organic solvent, and (c) at least one solid or liquid diluent. 15. The method of Claim 14 wherein the additional fungicidal compound is selected from the group consisting of maneb, cymoxanil, fenpropidine, fenpropimorph, phosethyl-Al, metalaxyl, oxadixyl, tebuconazole, difenoconazole, diniconazole, fluquinoxonazole, ipconazole, metconazole, penconazole, propiconazole, uniconzole, copper oxychloride, furalaxyl, folpet, flusilazol, probenazole, tricyclazole, and flutriafol. 16. The method of Claim 15 wherein the compound of Formula I is 3, 5-dihydro-2-methoxy-5-methyl-5-phenyl-3- (phenylamino) -4H-imidazol-4-one; or 3, 5-dihydro-5- methyl-2- (methylthio) -5-phenyl-3- (phenylamino) -4H- imidazol-4-one. 17. The method of Claim 16 wherein the compound of Formula I is 3, 5-dihydro-5-methyl-2- (methylthio) -5- phenyl-3- (phenylamino) -4H-imidazol-4-one and the additional fungicidal compound is cymoxanil. 18. A process for the preparation of imidazolinones of Formula la: la wherein R 1 is C i ~C 4 alkyl; C -C 4 haloalkyl; C 3 -C 6 cycloalkyl; C 2 -C 4 alkenyl; C 2 -C 4 alkoxy- carbonyl; or phenylmethyl optionally substituted with R 6 on the phenyl ring and with R 8 on the benzylic carbon; R 2 is Ci-C 20 alkyl optionally substituted with R 22 ; C 2 -C 20 alkoxyalkyl optionally substituted with R 35 ; C 2 -C 20 alkenyl optionally substituted with R 42 ; C 2 -C 20 alkynyl optionally substituted with R 41 ; (CH 2 CH 2 OCH 2 CH 2 )CH-; (CH 2 CH 2 SCH 2 CH 2 )CH-; (CH 2 CH 2 S0 2 CH 2 CH 2 )CH-; C 5 -C 7 cycloalkyl; C 5 -C 7 cycloalkenyl; phenyl optionally substituted with R 5 and R 7 ; 2-naphthalenyl; thienyl optionally substituted with R 5 and R 7 ; furyl optionally substituted with R 7 ; or pyridyl optionally substituted with R 5 and R 7 ; or R 1 and R 2 can be taken together to form a structure selected from the group consisting of —CH 2 (CH 2 ) 2 CH 2 _ , —CH (CH 2 ) 3 CH 2 —, —CH (CH 2 ) 4 CH 2 —, —CH 2 CH 2 0CH 2 CH 2 —, —CH 2 CH SCH CH 2 _ , R 3 is phenyl, pyridyl, or pyrimidinyl each optionally substituted with R 10 ; or phenyl¬ methyl; R 4 is H or methyl; and R 47 is Ci-C 8 alkyl optionally substituted with R 44 ; C 3 -Cg alkenyl or C 3 -C 6 alkynyl each optionally substituted with R 69 ; C 3 -C 6 cycloalkyl optionally substituted with 1-3 halogen; phenyl optionally substituted with R 57 and R 59 ; C(=0)R 52 ; C(=NR 55 )R 52 ; C(=0)OR 53 ; C[»N(C 1 -C 4 alkyl) ]OR 53 ; or C (=0)NR 53 R 56 ; R 5 is halogen; nitro; cyano; C^Cg alkyl; C 5 -C 6 cycloalkyl; Ci~Cg haloalkyl; C 1 -Cg alkylthio; Ci-Cg haloalkylthio; Cι-C 6 alkoxy; C 1 -C 6 haloalkoxy; C 5 -C 6 cycloalkyloxy; C 2 _Cg alkoxy¬ alkyl; C 2 -C 6 alkoxyalkoxy; C 3 -Cg alkenyl; C 3 -Cg haloalkenyl; C 3 -C 6 alkenyloxy; C 3 -C 6 alkynyl; C 3 _Cg haloalkynyl; C 3 -C 6 alkynyloxy; Ci-Cg alkylsulfonyl; Ci-C 6 haloalkylsulfonyl; phenyl or phenylthio each optionally substituted with R 24 ; phenylmethyl, phenoxymethyl, phenethyl, or styryl each optionally substituted with R 24 on the phenyl ring; phenoxy optionally substituted with R 27 ; benzyloxy optionally substituted with R 30 on the phenyl ring; -OC (=0)NHR 28 ; -C(=0)OR 28 ; or ~OC(=0)R 28 ; R 6 , R 7 , R 12 , R 24 , and R 26 are independently 1-2 halogen; nitro; C ~C alkyl; trifluoromethyl; methylthio; or Ci~C 4 alkoxy; R 8 , R 14 , R 38 and R 40 are independently H or Ci-C 4 alkyl; R 10 , and R 25 are each independently 1-2 substituents selected from the group consisting of halogen, nitro, cyano, C _C 4 alkyl, trifluoromethyl, Ci-C 4 alkylthio, C -C 4 alkoxy and trifluoro- methoxy; R 11 is independently Ci-C 6 alkyl; or phenyl optionally substituted with R 12 ; R 22 is cyano; nitro; C -C 19 alkylthio; C -C 19 alkyl¬ sulfinyl; Ci-C 19 haloalkoxy; C 5 -C 6 cycloalkyl¬ oxy; C 3 -C 19 alkenyloxy; C 3 -C 19 alkynyloxy; C -C 19 alkylsulfonyl; C 2 -C 19 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C (=0) 0; R 28 OC(=0)0; R 28 R 40 NC(=O)O; R 39 R 40 N; (Cι-C 4 alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 1 R 38 N + ; phenyl, phenylthio, phenoxy, phenylsulfonyl, phenyl¬ sulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; C 3 -C 6 cycloalkyl; 2-tetrahydropyranyloxy; or C(=Q)R 40 ; R 27 is 1-2 halogen; nitro; cyano; C^Cg alkyl; Ci~C 6 haloalkyl; C ~Cg alkoxy; C^C haloalkoxy; Ci~C 4 alkylsulfonyl; C 2 -Cg alkoxyalkyl; C -C 4 alkyl¬ thio; C 5 -Cg cycloalkyl; C 5 -C 6 cycloalkyloxy; C 2 -C 6 alkenyl; C 2 -C 6 haloalkenyl; C 2 -C 6 alkynyl; hydroxycarbonyl; C 2 -C 4 alkoxycarbonyl; or phenoxy optionally substituted with R 24 ; R 28 is C -C 8 alkyl; or phenyl or pyridyl each optionally substituted with R 30 ; R 30 is 1-2 substituents selected from the group consisting of halogen, nitro, cyano, Ci~C alkyl, trifluoromethyl, Ci~C alkoxy and trifluoromethoxy; or phenoxy optionally substituted with R 26 ; R 35 is cyano; nitro; Ci-C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci-C 17 haloalkoxy; C 5 -Cg cycloalkyl- oxy; C 2 -C 1 haloalkenyl; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; Ci-C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 0 NC(=O)O; R 0 R 39 N; (Ci~C 4 alkoxy) 2 P (=E) 0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenyl- thio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetra¬ hydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; C 2 -C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; C 3 -C 6 cycloalkyl; or C 2 _C 17 haloalkoxyalkoxy; R 39 is Ci-C 1 g alkyl; C 2 -C 19 alkylcarbonyl; C 2 -C 19 alkoxycarbonyl; (R 9 R 40 N) C=0; phenyl optionally substituted with R 25 ; or phenoxycarbonyl optionally substituted with R 7 ; R 41 is cyano; nitro; C -C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; Ci-C 17 haloalkoxy; C 5 -Cg cycloalkyl- oxy; C 3 -C 17 alkenyloxy; C 3 -C 17 alkynyloxy; Ci-C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C(=0)0; R 28 OC(=0)0; R 28 R 40 NC(=0)0; R 40 R 39 N; (C 1 -C 4 alkoxy) 2 P (=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydro- pyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 -C 17 alkoxyalkoxy; or C 3 -C 6 cycloalkyl; R 42 is cyano; nitro; C -C 17 alkylthio; Ci-C 17 alkyl¬ sulfinyl; C 1 -C 17 haloalkoxy; C 5 -C 6 cycloalkyl- oxy; C 3 -C 17 alkenyloxy; C 3 -C 17 haloalkynyl; C 3 -C 17 alkynyloxy; C _C 17 alkylsulfonyl; C 2 -C 17 alkoxycarbonyl; hydroxyl; hydroxycarbonyl; R 28 C (=o)0; R 28 0C(=0)0; R 28 R 40 NC (=0) 0; R 40 R 39 N; (C 1 -C alkoxy) 2 P(=E)0; R 1:L S0 3 ; R 40 R 14 R 38 N + ; phenyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, pyridyl or pyridyloxy each optionally substituted with R 30 ; thienyl, pyrimidinyl, furanyl, naphthalenyl, pyrimidinyloxy, naphthalenyloxy each optionally substituted with R 7 ; tetrahydropyranyl; 2-tetrahydropyranyloxy; Ci-C 17 alkoxy; 1-3 halogen; C 2 _C 17 alkoxyalkoxy; C 3 -C 17 alkynyl; or C 3 -C 6 cycloalkyl; R 44 is 1-3 halogen; cyano; nitro; Cι~Cg alkoxy; c ι _c 6 haloalkoxy; C 2 -C 6 alkoxyalkoxy; C^Cg alkylthio; Ci~Cg alkylsulfonyl; phenyl or phenoxy each optionally substituted with R 57 and R 59 ; NR 49 R 50 ; or R 62 ; R 49 is H; Ci~C alkyl; C 3 -C 4 alkenyl; or cyclo- propyl; R 50 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; C 3 -C 6 haloalkenyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; or R 49 and R 50 can be taken together to form - (CH 2 ) -; -(CH 2 ) 5 - or -CH 2 CH 2 0CH 2 CH 2 -; R 52 is H; C 1 -C 4 alkyl; Ci-C 4 haloalkyl; C 2 -C 4 alkenyl; C 2 -C 6 haloalkenyl; or phenyl optionally substituted with R 57 ; R 53 is H; Ci-C alkyl; C 3 -C 6 alkenyl; C 3 -C 6 haloalkenyl; C 3 -C 6 alkynyl; C 2 -C 6 alkoxyalkyl; phenyl optionally substituted with R 58 and R 59 ; or phenylmethyl optionally substituted with R 58 and R 59 on the phenyl ring; R 54 , R 55 and R 56 are each independently H or C ~C 4 alkyl; R 57 is 1-2 halogen; nitro; CF 3 ; methoxy; methyl; or cyano; R 58 is halogen; nitro; CF 3 ; OCF 3 ; methoxy; methyl; ethyl; methylthio; cyano; or methoxycarbonyl; R 59 is halogen or Ci-C 4 alkyl; R 62 is C(=N-V-R 53 )R 52 ; C (=0) OR 53 ; C (=0)NR 53 R 56 ; C(=NR 55 )0R 53 ; C(=NR 55 )NR 53 R 56 ; OC(=0)R 52 ; SC(=0)R 52 ; N(R 56 )C(=0)R 52 ; OC (=NR 55 )R 52 ; N(R 56 )C(=NR 55 )R 52 ; OC(=0)OR 53 ; OC (=0)NR 53 R 56 ; OC(=S)SR 53 ; SC(=0)OR 53 ; N (R 56 ) C (=0)OR 53 ; or N (R 56 ) C (=NR 55 )NR 53 R 54 ; R 69 is 1-3 halogen; cyano; nitro; or C(=0)OR 54 ; comprising reacting of an alpha-bis (thio)methyleneamino acid ester of Formula 7 wherein R 1 , R 2 and R 47 are as defined above for Formula la; and Z is Ci~C 4 alkyl, C 3 -C alkenyl, C 3 -C 6 cycloalkyl, or C 6 H 5 CH 2 ; with a hydrazine of Formula 3 NH 2 NR 3 R 4 3 wherein R 3 and R 4 are as defined above for Formula la; to yield a compound of Formula la.

Inventors: SUN KING-MO, SUN, KING-MO
Applicants: DU PONT, SUN KING MO, E.I. DU PONT DE NEMOURS AND COMPANY
Application year: 1993
Main classification: C07D233
IPC codes: A01N43, C07D233, C07D235, C07D409, C07D491