STABILIZATION OF MICROEMULSIONS USING HYDROPHOBIC ACID BUFFERS

Abstract: A highly stable composition composed of a water insoluble agriculturally active ingredient, a surfactant, a lactam having formula (I) wherein R is hydrogen or a branched or straight-chained alkyl having from 1 to 16 carbon atoms, R1 is a branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R1 is less than or equal to 16; and n is 3, 4, or 5; and at least about 80 % by weight water, and wherein the specific agriculturally active ingredient, surfactant and lactam and amounts of each are such that the composition is in the form of a microemulsion. Also disclosed are microemulsion compositions which exhibit increased stability for agriculturally active ingredients which are subject to hydrolysis and microemulsion compositions which exhibit improved cold temperature stability.

Description: STABILIZATION OF MICROE ULSIONS USING HYDROPHOBIC ACID BUFFERS BACKGROUND OF THE INVENTION I. Field of the Invention The invention relates to a delivery system for agriculturally active chemicals. More particularly, the invention relates to a microemulsion of a difficult to dissolve agricultural chemical and concentrates for produc¬ ing such microemulsions. II. Definitions As used herein, the following terms have the meanings indicated: (a) "macroemulsion" means an emulsion of water in oil or oil in water wherein the interior phase is in the form of visually discernable droplets and the overall emulsion is cloudy, and wherein the droplet diameter is greater than about 100 millimicrons. (b) "microemulsion" means an oil in water or water in oil, transparent thermodynamically stable dispersion of two or more immiscible liquids wherein the dispersed phase consists of small droplets with diameters in the range of about 10 to 100 millimicrons. Such microemulsions are clear and contain at least about 80% by weight water. (c) "clear" or "transparent" as applied to a microemulsion means that the composition appears as a single phase without any par¬ ticulate or colloidal material or a second 5 phase being present when viewed by the naked eye. (d) "substantially insoluble" or "insoluble" means that for all practical purposes, the solubility of the compound in water is in- 10 sufficient to make the compound practicably usable in an agricultural end use without some modification either to increase its solubility or dispersability in water, so as to increase the compound's bioavailability 15 or avoid the use__of excessively large vol¬ umes of solvent. (e) high degree of loading in the concentrate means an agriculturally active ingredient content of at least about 4 percent by 20 weight. (f) the term "agriculturally active chemical or ingredient" (AAC) means compounds and mix¬ tures thereof which can be used as agricul¬ tural fertilizers, nutrients, plant growth 25 accelerants, herbicides, plant growth con¬ trolling chemicals, and chemicals which are effective in killing plants, insects, micro- organisms, fungi, bacteria and the like which are commonly referred to as insecti¬ cides, bactericides, fungicides, nemato- cides, fu igants, synergists, i.e., com- 5 pounds which when used in conjunction with other AAC's enhance their activity and the like, as well as any other chemicals having properties which are suitable for agricul¬ tural uses in terms of application to plants 10 or domestic uses for controlling insects and pests. (g) the term "unstable" when applied to an agri¬ culturally active chemical means that the chemical is subject to degradation or dete- 15 rioration when mixed with water. (h) the term "buffering effective amount" means an amount of hydrophobic acid sufficient to buffer the mixture to a pH so as to minimize the hydrolysis of the AAC. 20 (i) the term "cold temperature stability" in connection with a microemulsion means that the microemulsion remains clear for periods of at least one month at 2-3°C. BACKGROUND OF THE INVENTION Agricultural chemicals are most preferably applied in the form of aqueous emulsions, solutions, or suspensions. Occasionally, they may also be applied in the form of a dust wherein the active ingredient is adsorbed onto or mixed with a finely divided inert carrier material, such as, china clay, or the like. With such powdered or • dust compositions, drift due to wind is a problem and consequently, liquid formulations are preferred. One of the problems with such liquid formulations is the fact that chemicals having agricultural activity often exhibit extreme insolubility in water. This results in their having to be dissolved either in organic solvents or utilized in the form of emulsions or suspensions. With respect to the use of organic solvents, these are generally disadvantageous from an environmental and cost viewpoint. Particularly, such organic chemicals may exhibit toxicity or side-effects which may be adverse to the effect of the agricultural chemical itself or to the subsequent fruit or vegetable produced in the particular agricultural use. This toxicity may also be disadvantageous with respect to handling. When attempts are made to provide emulsified or suspension formulations, difficulties are encountered with respect to providing a desirably high concentration of the agriculturally active ingredient. Thus, when such agricul¬ turally active chemicals are formulated into a macroemul- sion (sometimes referred to herein as an emulsion) , it is difficult to maintain the emulsified state. This, in turn, creates problems in maintaining a uniform formulation, particularly, when the formulation is diluted with water for application to the plants. An attempt to provide concentrates of agricultur- ally useful chemicals for producing macroemulsions is disclosed in South African Patent Application No. 695,393, filed July 25, 1969. This application is directed to the formulation of a concentrate of substantially water-insolu¬ ble pesticides for agricultural use. The pesticides, either in oil or solid form, are mixed with pyrrolidones having a hydrogen or a lower alkyl group containing from 1 to 4 carbon atoms attached to the nitrogen atom of the pyr¬ rolidone ring. The application discloses that concentrated solutions of difficult to dissolve pesticides could be formulated and that such concentrates exhibited good sta¬ bility. The concentrates utilized are those containing the pesticidal active ingredient, the particular lower alkyl pyrrolidone, a co-solvent which is usually a common organic solvent, such as, an aromatic including xylene, methylated and polyalkylated naphthalenes and aliphatic solvents, and a dispersing or emulsifying agent, such as, a surfactant, including polyoxyethylene alk lphenols, polyoxyethylene fatty esters, polyoxyethylene sorbitan fatty esters which may be blended with oil-soluble sulfonates, calcium and aminosulfonate salts, and the like. This prior art does not offer a solution to the problem arising from the difficulty in maintaining the stability of the emulsion after the concentrate is diluted with water. Consequently, unless the diluted form of the concentrate is used immediately after emulsification, it is difficult to provide a stable diluted formulation for application to the plants, soil, pests, and the like. U.S. Patent No. 4,798,837 discloses an emulsifi- able concentrate of the pesticidal compound (CGA) : F C I r- This active concentrate contains 10% of the active ingredient using 30% cyclohexanone as the solvent. However, cyclohexanone is highly toxic. For such agricul¬ tural uses, it is desirable to avoid the use of toxic sol¬ vents, including those of Lists 1 and 2 of 40 C.F.R. 154.7 dated April 22, 1987, which includes inerts of toxicologi- cal concern and solvents having high flash points, as well as to increase the amount of the agriculturally active material in the concentrate. Moreover, many organic sol¬ vents which have been used in the past, even those exhibit- ing relatively low toxicities, are not biodegradable and thus remain as a pollutant. U.S. Patent Application Serial Nos. 546,014, filed, June 28, 1990, 505,030, filed April 5, 1990, and 07/448,707, filed December 11, 1989, have provided solu- tions to the problem of providing stable macroemulsions of insoluble agricultural chemicals in aqueous systems. This is accomplished by the use of long and short chain alkyl lactams for formation of emulsifiable concentrates of agricultural chemicals. Also see U.S. patent application Serial No. 257,596, filed October 14, 1988, the contents of which are incorporated herein by reference, which discloses the use of long chain alkyl lactams to prepare emulsifiable concentrates of agriculturally active ingredients, e.g. , herbicides, fungicides, pesticides, and the like, which on dilution with water, form stable macroemulsions. While these patent applications disclose the preparation of emulsions of a wide variety of agricultural¬ ly active chemicals which are normally highly insoluble in water, the emulsions produced from all of these prior art concentrates are macroemulsions. The macroemulsions which result from their dilution with water, while relatively stable, may, at some point in time, settle out into two or more phases. It is desirable, however, to provide compositions which will deliver effective amounts of insoluble agricul¬ turally active compounds which exhibit improved stability with respect to the emulsion. In addition, it is desired • to provide increased chemical stability for such agricul¬ tural compounds. It is also desirable to increase the efficacy of a given agricultural compound relative to its loading content. It has been theorized that microemulsions can improve the efficacy of agriculturally active compounds relative to equivalent levels of the same compound in a acroemulsion composition. See Skelton, P.R., Munk, B.H. , and Collins, H.M. , "Formulation of Pesticide Microemul¬ sions", Pesticide Formulations and Application Systems; 8th Volume, ASTM STP 980. D.A. Hovde and G.B. Beestman, Eds., American Society for Testing and Materials, Philadelphia, 1988. See also U.S. Patent 3,954,967, and Canadian Patent 1025687. For a discussion of Microemulsions, see Micro¬ emulsions, Theory and Practice, Leon M. Prince, Academic Press, 1977 and Microemulsions-Properties Novel Chemistry BH Robinson, Chemistry in Britain 2_\ (1990), page 342. SUMMARY OF THE INVENTION We have discovered a novel microemulsion which can be used to place highly water insoluble agriculturally active compounds in a state, which is essentially equiva- lent to a dissolved state, which microemulsions exhibit prolonged stability. More particularly, we have discovered a highly stable composition composed of a water insoluble agricul¬ turally active ingredient, a surfactant, a lactam having the formula: wherein R is hydrogen or branched or straight chained alkyl having from 1 to 16 carbon atoms and R,, is branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R 1 is less than or equal to 16; and n is 3, 4, or 5; and at least about 80 percent by weight water, and wherein the specific agriculturally active ingredient, surfactant, and lactam and amounts of each are such that composition is in the form of a microemulsion. Of importance with the microemulsions of the present invention is the fact that even though they contain large amounts of water, they exhibit a long shelf life in the microemulsion form. This is of special advantage for consumer end uses, e.g., household uses, domestic pest control, and those end uses wherein dilution of a concen¬ trate at the site is unfeasible or undesirable. In addi- tion, the inventive compositions do not contain any mate¬ rials which are disadvantageous from an environmental point of view, e.g., toxic solvents and the like. However, certain AAC's are known to be unstable under certain conditions, for example, they may hydrolyze in water, e.g., carbamates, pyrethroids or esters, amides, phosphate esters, thiophosphates esters, and the like. Typical of these are hydramethylnon, carbaryl, and the like. Generally, for such a compound, stability of four hours has been considered satisfactory since the diluted material would, as a practical matter, have to be used shortly after dilution. However, this means that these compounds cannot be stored for prolonged periods of time. In addition, we have discovered that for those AAC's which are normally unstable in water, i.e., subject to hydrolysis, a highly stable microemulsion can be ob¬ tained by including in the above mixture a buffering effective amount of a hydrophobic acid. Also, in certain geographic areas, it is also desirable that compositions maintain the microemulsion state at temperatures below 10°C, and generally, as low as 3 β C. Ordinarily, it has been observed that such microemul- • sions become unstable, as evidenced by visible cloud of the otherwise transparent liquid as the temperature is de- creased below about 10°C. Also, we have found that the cold temperature stability of such AAC's can be improved by the addition to the above-defined mixture, a cold temperature effective stabilizing amount of a polyhydric alcohol. BRIEF DESCRIPTION OF THE DRAWINGS Figures 1, 2 and 3 are photomicrographs of micro¬ emulsions of Carbaryl. DETAILED DESCRIPTION OF THE INVENTION Agriculturally active chemicals which can be used with the present invention normally take the form of water- immiscible or oily liquids and/or solids and include insec- ticides, such as, cyclo compounds, carbamates, animal and plant derivatives, synthetic pyrethroids, diphenyl com¬ pounds, non-phosphates, organic phosphates, thiophosphates, and dithiophosphates. (See Agricultural Chemicals, Book I, Insecticides, 1989 Revision by W.T. Thomson, Thomson Publi¬ cations.) cyclocompounds: 6,7,8,9,10,10-hexachloro- 1,5,5a,6,9,9a-hexahydro-6,9-metha- no-2,4,3-benzodioxathiepin-3-oxide carbamates: 2-isopropyl phenyl-N-methyl carba- mate; 2- ( 1 , 3 -dioxolan-2yl ) phenylmethyl carbamate ; 2,3-isopropylidine dioxyphenyl methyl carbamate; Carbaryl: 1-naphthyl-N-methylcarbamate animal and plant derivatives: chlorinated hydrocarbons derived from Southern pine; naturally occurring lactone glycoside; synthetic pyrethroids: (±) α-cyano-3-phenoxybenzyl (±) cis, trans 3-(2,2-dichlorovinyl)- 2,2-dimethyl cyclopropane carbox- late; (RS)-3-allyl-2-methyl-4- oxocyclopent-2-enyl (IRS)- cis,trans-chrysanthemate; 3-phenoxybenzyl (IRS)-cis,trans-3- (2,d-dichlorovinyl)-2,2-dimethyl- cyclopropanecarboxylate; 3,4,5,6-tetrahydrophthalimido- methyl (±)-cis,trans-chrysanthema- te); 5-[2-(2-*butoxyethoxy)ethoxy- methyl]-6-propyl-l,3-benzodioxole; * this compound is a known synergist for synthetic pyrethroids (RS)-α-cyano-3-phenoxybenzyl 2,2,3,3-tetramethylcyclopropane- carboxylate; (±) cyano (3-phenoxypheny1 methyl (±)-4-(difluoromethyoxy) α-(l- methylethyl) benzene acetate; phenoxy compounds and non-phosphate: 2,2-bis(p-methoxy phenyl)- 1,1,1,trichloroethane; 1,3,5,tri-n-propyl-1,3,5-triazine- 2,4,6 (1H,3H,5H) trione; ethyl (2E, 4E)-3,7,ll-trimethyl- 2,4-dodeca dienoate; 1- [ 4-) 2-chloro-α , a , ce-trif luoro-p- tolyloxy) -2-fluorophenyl ] -3- (2 , 6- difluorobenzoyl)urea; 1-decycloxy 4-[(7-oxa-oct-4- ynyl) ]-oxybenzene; organic phosphates: dimethyl phosphate ester of 3-hy- droxy-N,N-dimethyl-cis-croton- amide; 2-chloro-l-(2,4-dichloro phenyl) vinyl diethylphosphate; 4-(methyl thio) phenyl dipropyl phosphate; thiophosphates : 0,0-diethyl-0-4-nitrophenyl phos- phorothioate; 0,0-diethyl-O-(2,isopropyl-6-meth- yl-5-pyrimidinyl) phosphoro- thioate; 2-diethylamino-6-methyl pyri i- dine-4-yl dimethyl phosphoro- thioate; dithiophosphates 0,O-dimethyl phosphorodithioate and others: ester of diethylmercapto succi- nate; O-ethyl-S-phenyl ethyl phosphoro¬ dithioate; 5,5-dimethylperhydropyrimidin-2- one 4-trifluoromethyl-α:-(4-tri- fluoromethylstyryl)-cinnamylidene- hydrazone (hydramethylnon) . Typical herbicides include phenoxy compounds, benzoic, acetic, and phthalic acids, aniline derivatives, nitriles, amides, acetamides, anilides, carbamates, thio- carba ates, and heterocyclic nitrogen derivatives, e.g., triazines, pyridines, pyridazones, picolinic acid, and urea derivates and phosphates. (See Agricultural Chemicals, Book II, Herbicides, 1986-87 Edition, W.T. Thomson, Thomson Publications, Fresno, CA 93791.) Exemplary of the above compounds are: phenoxy compounds: 2,4-dichlorophenoxy acetic acid; 2,4,5-trichloro phenoxyacetic acid; 4-(2,4-dichlorophenoxy) butyric acid; S-ethyl 2 methyl-4-chlorophenoxy- thioacetate; 2-methyl-4-chloro-phenoxy acetic acid; methyl 5-(2,4-dichloro-phenoxy)-2- nitrobenzoate; benzoic and acetic acids of phthalic compounds: 3,6-dichloro-o-anisic acid; 4-chloro-2-oxo benzothiazolin-3-yl acetic acid; N-1-Naphthyl-phthalamic acid; nitriles and aniline derivatives: 3-5-dibromo-4-hydroxybenzo-nitrile; r α,α,trifluoro-2,6-dinitro-N, N-dipropyl-p-tolinidine; N-(1-ethylpropyl)-2,6-dinitro-3,4- xylidine; amides, acetamides, anilides: N,N-diethy1-2-(1-naphthalenyl ox )-propionamide; 2 r 6-dimethyl-N-2' methoxy-ethy1- chloro-acetanilide; 3',4'-dichloro-propionanilide; α-chloracetic-N-(3,5,5-trimethyl- cyclohexen-1-yl)-N-isopropylamide; 4-benzyl-N-isopropyl trimethyl acetamide; thiocarba ates: S-Ethyl dipropyl thiocarbamate; urea derivatives: 3-(5-tert-butyl-3-isoxazoyl)-1,1- dimethyl urea; N-(2,6-trifluoro-benzoyl)-N'-[2,5- dichloro-4-(1,1,2,3,3,3-hexa- fluoropropyloxy) phenyl] urea; pyrrolidone derivatives: 1-(m-trifluoro methyl phenyl)-3- chloro-4-chloromethyl-2- pyrrolidone; a ino acid derivatives: methyl N-benzoyl-N-(3-chloro-4- fluorophenyl)-DL alarinate; N-chloroacetyl-N-(2,6-diethyl phe¬ nyl)-glycine ethyl ester; carbamates: isopropyl-m-chlorocarbanilate; 3-ethoxy (carbonyl a inophenyl)-N- phenyl carbamate; heterocyclics: 4-amino-3 ,5-dichloro-6-fluoro-2- pyridyloxy acetic acid; 4-(l,2-Dimethyl-N-propyl amino)-2- ethyl amino-6-methyl thio-S-tri- azine; 2-[4,5-dihydro 4-methyl-4-(1-meth- yl ethyl)-5-oxo-l H-imidazoyl-2yl- 3-pyridinecarboxylic acid; 2-[3,5-dichlorophenyl)-2-(2,2,2- trichloroethyl) oxinane; butyl-9-hydro-fluorene-(9)-carbox- ylate; 2-[l-(ethoxy imino) butyl]-3-hy- droxy-5-(2H-tetra hydro thiopyran- 3-yl)-2-cyclohexene-ione; 2-(2 chlorophenyl) methyl-4,4-di- methyl-3-iso oxazolidinone; phosphates: 0-ethyl-0-(3-methyl-6-nitro phe¬ nyl) N-sec-butyl phosphoro thio amidate. Typical fungicides include (See Agricultural Chemicals, Book IV, Fungicides, 1989 Revision, W.T. Thomson, Thomson Publications, Fresno, CA 93791) : organic compounds: 2,5-dimethyl-N-cyclohexyl-N- methoxy-3-furan carboxamide; 5-ethoxy-3-trichloromethyl-l,2,4- thiadiazole; 3-(2-methyl piperidino) propyl 3,4-dichlorobenzoate; N,N'-(l,4-piperazinediyl bis (2,2,2-trichloro) ethylidene) bis formamide; tetra ethyl thiura disulfide; 0-Ethyl-S,S,diphenyl-dithiophos- phate; 5,10-dihydro-5,10-dioxo naphtho (2,3,9)-p-dithiin-2,3-dicarbo-ni- trile; 2-(thiocyano methyl thio) benzo- thiazole; α-2-(4-chlorophenyl) ethyl]-α- (1,1-dimethyl ethyl)-1 H-1,2,4- triazole-1-ethanol; morpholines: N-trideσyl-2,6-dimethyl morpholine; 4-N-dodecyl-2,6-dimethyl morpholine. Typical fumigants, growth regulators, repellants, and rodenticides include (See Agricultural Chemicals, Book III, Fumigants, 1988-1989 Revision, W.T. Thomson, Thomson Publications, Fresno, CA 93791) : growth regulants: 1,2 Dihydro-6-ethoxy-2,2,4-tri- methylquinoline; (2-chloroethyl) phosphoric acid; 4-[acetamino) methyl]-2-chloro-N (2,6-diethyl phenyl acetamide; Benzoic acid, 3,6 dichloro-2- methoxy,2-ethoxy-l-methyl-2-oxo ethyl ester; repellants: 0,O-dimethyl-0-[ (4-methyl thio)-m- tolyl] phosphorothioate; tertiary butyl-sulfonyl dimethyl dithio carbamate; seed softener: 2-chloro-6-(trichlomethyl) pyridine; 5-ethoxy-3-trichloromethyl-l , 2 , 4- thiadiazole; N-phenyl-N' -1 , 2 , 3-thiadiazol-5-yl urea. Pesticides may be characterized by their physical properties, depending on their physical state at normal or ambient conditions, i.e., between 40° F. and 90° F. and their solubility or miscibility with water or other common organic solvents, e.g., aromatics, such as, toluene, xy- lene, methylated and polyalkylated naphthalenes, and ali¬ phatic solvents. Based on the physical properties, the pesticides may be classified into two groups. The first group in¬ cludes those which are oily liquids at ambient temperatures • and are immiscible with water. Specific pesticides include: Common esters of 2,4-dichlorophenoxyacetic acid, Common esters of 2,4,5-trichlorophenoxyacetic acid, Common esters of 2-(2,4-dichlorophenoxy) propionic acid, Common esters of 2-(2,4,5-trichlorophenoxy) propionic acid, Common esters of 2,4-dichlorobutyric acid. Common esters of 2,methoxy-3,6-dichlorobenzoic acid, Common esters of 2-methyl-4-chlorophenoxyacetic acid, Piperonyl butoxide 3,4-methylenedioxy-6-propyl benzyl n- butyl diethylene glycol ether, Bromophos ethyl: 0,0-diethyl-0-2,5-dichloro-4-bromophenyl thionophosphate, N-(2-mercaptoethyl) benzene-sulfona ide (BETASAN ® ) , Isobornyl Thiocyanoacetate (Thanite ® ) , Ioxynil ester of octanoic acid, Molinate S-ethyl hexahydro - 1 H - azepine-1-carbothioate, PP 511 0,0-dimethyl-(2-diethylamine 4-methyl-6-pyrimidinyl) carbamate, PP 211 0,0-diethyl 0-(2-diethylamine-4-methyl-6- pyrimidinyl) phosphorocarbamate, 5-Ethoxy-3-(trichlorometyl)-1,2,4-thiadiazole (TERRAZALE ® ) , Ethyl-s-s-dipropyl-phosphodithioate (MOCAP*) , S-Ethyl dipropylthiocarbamate (EPTAM ® ) , S_-Ethyl diisobutylthiocarbamate (SUTAN ® ) , S-n. propyl-di-n-propylthiocarbamate (VERNAM ® ), S-propyl butylethylthiocarbamatae (TILLAM ® ) , S-ethyl ethylcyclohexylthiocarbamate (RO-NEET ® ) , Malathion (S-(l,2-dicarboxyethyl)-0,0-dimethyl phosphorodi- thioate) , Diazinon (0,0-diethyl,0-(2-isopropyl-4-methyl-6- pyrimidinyl) phosphorothioate, O-Ethyl-S-phenyl-ethylphosphonodithioate (DYFONATE ® ) , Toxaphene (Octachlorocamphene) , Bromoxynil (3,5-dibromo-4-hydroxy benzonitrile ester of n.octanoic acid, 2-chloro-N-2,6-diethylphenyl-N-methoxymethylacetamide (LASSO ® ) , Diallate S-2,3-dichloroallyl N,N-diisopropylthiolcarbamate, Triallate S-2,33-trichloroallyl N,N-diisopropylthiol- carbamate. The second group comprises those pesticides which are solids at ambient temperatures and for all practical purposes, insoluble in water. 2,4,5-T (2,4,5-trichlorophenoxy acetic acid) Monuron (3-(p-chlorophenyl)-1,1-dimethyl urea) Diuron (3-(3,4-dichlorophenyl)-l,1-dimethyl urea) Bromacil (5 bromo-3-sec. butyl-6-methyl uracil) Isocil (5 bromo-3-isopropyl-6-methyl uracil) Linuron (3-(3,4 dichlorophenyl)-l-methoxy-l methyl urea Atrazine (2-chloro-4-ethylamino-6 isopropylamino-s- triazine) Simazine (2-chloro-4,6,-bis (ethylamino)-s-tri- azine ■ Dodine (n-dodecylguanidine acetate) Thiram (tetrameth lthiuram disulfide) N-(mercaptomethyl)phthalimide s_-(o,o dimethylphosphoro- dithioate) (IMIDAN ® ) Lindane (gamma 1,2,3,4,5,6 hexachlorocyclohexane) Folpet (N-trichloromethylphthalimide) Manazon (s-(4,6-diamino-l,3,5-triazin-2-yl methyl)dimethyl phosphorothiolthionate) Barban (4-chloro-2 butynyl m-chlorocarbanilate) Tricumba 2-methoxy-3,5,6-trichlorobenzoic acid Trifluralin (2,6-dinitro-N,N-dipropyl-4-trifluoro- methylamiline) (2,3 dihydro-5-carboxanilido-6-methyl-l,4- oxathiin) (VITAVAX ® ) 2,4-dichlorophenoxyacetic acid 4-(4-chloro-2 methylphenoxy) butyric acid 2-(2,4-dichlorophenoxy) propionic acid Ioxynil: 3,5 diiodo-4-hydroxybenzonitrile Bromoxynil: 3,5 dibromo-4-hydroxybenzonitrile Methoxychlor: 2,2,-Bis(p-methoxyphenyl)-1,1-trichloroethane PP 781: 4(2-chloro phenylhydrazono)-3-methyl-5-isoxazolone* PP 675: 5-butyl-2-dimethylamino-4-hydroxy-6-methyl pyrimidine* PP 062: 5,6-dimethyl-2-dimethylamino-4 pyrimidinyl dimethylcarbamate* PP 149: 5-n-butyl-2 ethylamino-4-hydroxy-6 methylpyrimidine* * Manufactured by Imperial Chemical Industries Limited C 6313 N'-(4-bromo-3-chlorophenyl)-N-methoxy-N-methylurea C 6989 2,4'dinitro-4-trifluoromethyl-diphenylether Chloroxuron N'-4-(chlorophenoxy) phenyl-NN-dimethylurea Dichlobenil 2,6-dichlorobenzonitrile Diphenamid NN-dimethyl-2,2-diphenylacetamide Fenac 2,3,6-trichlorophenylacetic acid Fluometuron N'-(3-trifluoromethylphenyl)-NN-dimethylurea GS 14260 4-ethylamino-2-methylthio-6-t-butyl-amino-l,3,5- triazine PCP Pentachlorophenol Lenacil 3-cyclohexyl-6,7-dihydro-lH-cyclo-pentapyrimidine- 2,4-(3H,5H)-dione Pyrazon 5-amino-4-chloro-2-phenyl-3-pyridazone Metrobromuron N'-(4-bromopheny1)-N-methoxy-N-methylurea Metoxy arc N-(4-methoxybenzoyl)-N-(3,4-dichlorophenyl)- N' ,N'-dimethylurea Neburon N-butyl-N'-(3,4-dichlorophenyl-N-methylurea NIA 11092 l,l-dimethyl-3-[3-(n-t-butyl carbamyloxy)phenyl] urea Mecoprop 2-(4-chloro-2 methylphenoxy)propionic acid Monolinuron N'-(4-chlorophenyl)-N-methoxy-N-methylurea Nitrofen 2,4-dichlorophenyl 4-nitrophenylether Propanil N-(3,4-dichlororphenyl)propionamide Pyriclor 2,3,5-trichloro-4-pyridinol Solan 3'-chloro-2-methyl-p-valerotoluidide Terbacil 5-chloro-3-t-butyl-6-methyluracil UC 22463 (SIRMATE)-3,4-dichlorobenzyl N-methylcarbamate • WL 9385 2-Azido-4-ethylamino-6-t-butylamino-s-triazine Propachlor 2-chloro-N-isopropylacetanilide CP 50144 2-chloro-N-2,6-diethylphenyl-N- ethoxymethy1acetamide CP 31675 2-chloro-N-(2 methyl-6-t-butylphenyl)acetamide Cypromid 3',4'-dichlorocyclopropane carboxanilide Fenuron NN-dimethyl-N-phenylurea Chlorbromuron '-(4-bromo-3-chlorophenyl)-N-methoxy-N- methylurea Ametryne 2-methylmercapto-4-ethylamino-6-isopropyl-amino-s- triazine Prometryne 2-methylmercapto-4,6-bisisopropyl amino-s-tri- azine DCPA dimethyl 2,3,5,6, tetrachloroterephthalate Benefin N-butyl-N-ethyl-2,2,2-trifluoro-2,6-dinitro-p- toluidine Nitralin 2,6-dinitro-4-methylsulfonyl-NN-dipropyl-aniline PP 493 2,6-difluoro-3,5-dichloro-4-hydroxy pyridine CNP 2,4,6-trichlorophenyl-4'-nitrophenyl ether Pentachloro nitrobenzene 1-(butyl carbamoyl)-2-benzimidazole carbamic acid, methyl ester (BENLATE ® ) which normally exhibit instability when added to water due to hydrolysis. Typical water unstable insecticides include carbamate esters, amides, phosphate esters, thiocarbamates, thiophosphate esters or esters of thiophosphates. These include Carbaryl, Aminocarb, alphacypermethrin, Resmethrin, Allethrin, Diflubenzuron, Dicrotophos, Profenofos, Azinphos-methyl, Methfuroxam, Procymidone, Fthalide, Nitrothal-isopropyl, Tolclofos-methyl, Pyrazophos, Chlorop- ropham, EPTC, DPX-L5300, DPX-F 5384, and Naptalam. (De¬ tailed descriptions of each of these chemicals are set forth in Agricultural Chemical Books I,II, III, and IV, Insecticides. 1989; Herbicides, 1986-1987; Fumigants and Growth Regulators, 1988; Revision by W.T. Thomson, Thomson Publications. ) Preferred lactams suitable for use in the inven¬ tion are alkyl pyrrolidones having the formula: wherein R is hydrogen or linear or branched alkyl having from 1 to 16 carbon atoms and R 1 is linear or branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R., must be less than or equal to 16. Preferred lactams are those wherein R is hydrogen and R 1 is methyl, ethyl, butyl, octyl, or iso-octyl. Of these, particularly preferred are N-methyl pyrrolidone, N- octyl pyrrolidone, and N-isooctylpyrrolidone. The method of preparing the inventive composition involves merely admixing the ingredients. Normally, it is best to first add the agriculturally active compound to the lactam component and then admix the surfactant. The water is normally added after the first three ingredients are mixed. However, there is no particular criticality to the sequence of addition and mixing. Surfactants suitable for use in the inventive composition include ethoxylated alkyl phenols, linear ali¬ phatic polyesters, linear aromatic polyesters, polyalkenyl- oxyalcohol, linear aliphatic ethoxylates, polyethoxylated castor oil, polyethoxylated carboxylates, and poly- ethoxylated alkylamines. Anionic surfactants may be used as the emulsifier and include phosphate esters and their salts, alkyl sulfates, sulfonates, and their salts, salts of sulfated nonylphenoxypoly(ethyleneoxy) ethanol, salts of alk lbenzene sulfonates, salts of alkylnaphthalene sulfonate, and sulfonated aliphatic polyesters and their salts. Also suitable are complex phosphate esters of non- ionic surfactants of the ethylene oxide type which are mix¬ tures of diesters of phosphoric acid. (See, for example, McCutcheon's, Emulsifiers and Detergents (1989) , published by McCutcheon's Division of M.C. Publishing Co., Glen Rock, New Jersey.) Suitable hydrophobic acids for use in the present invention are those which produce a buffering effect on the composition so as to inhibit the hydrolysis or deteriora¬ tion of the AAC and yet not deleteriously affect its in¬ tended performance or the state of the microemulsion. Typical are hydrophobic acids having a pK a of from about 2 to 5. These include nonylphenyl ethoxylated phosphoric acid with an ethylene oxide unit content, i.e, -0-CH 2 CH 2 units (hereinafter referred to as EO units) of from 3 to 18, R 2 COOH wherein R 2 is alkyl containing from 7 to 17 carbon atoms and which may contain from about 1 to 10 EO units, wherein R 3 is alkyl containing from 8 to 18 carbon atoms and which may contain from about 1 to 10 EO units, R 4 -S0 3 H wherein R 4 is alkyl containing from 8 to 18 carbon atoms and which may contain from about 1 to 10 EO units, R 5 OS0 3 H wherein R 5 is an alkyl group containing from 8 to 18 carbon atoms, and which may contain from about 1 to 10 EO units. Suitable polyhydric alcohols for use in the present invention are glycerol, pentaerythritol, mannitol, and sorbitol. The amount of the polyhydric alcohol is that which is sufficient to provide cold temperature stability but not deleteriously affect its intended performance. More specifically, the amount of the polyhydric alcohol may be in the range from about 1 to 50 percent by weight, preferably, 2 to 20 percent, and most preferably, 2 to 5 " percent by weight based on the total weight of the mixture in the end use formulation. More specifically, the hydrophobic acid may be present in an amount from about 0.01 to 20 percent by weight, preferably, 0.002 to 10 percent, and most prefera¬ bly, 0.05 to 1.0 percent by weight, based on the total weight of the mixture in the end use formulation. The amount of hydrophobic acid in the concentrate can be from about 0.05 to 25 percent by weight. The specific components as well as their amounts in the inventive composition may be revised over a wide range within the definitions given above, and are limited only in that the final product, upon dilution, must form the inventive microemulsion. The AAC concentration should be as high as possi¬ ble so long as it does not precipitate upon dilution of the concentrate with at least 80% weight water for a reasonable period of time and achieves the desired effect. Precipita¬ tion (crystal formation) on standing not only depletes the amount of AAC in solution, it can also lead to fouling of application equipment, i.e., sprayers, etc. With the present invention, it is possible to obtain concentrates with .AAC concentrations in excess of 4 weight percent which form a stable, transparent microemul¬ sion upon being diluted with water. Depending on the particular AAC, the concentration of the AAC in the con¬ centrate is from about 4 to 25% based on the total weight of the composition before dilution. Generally, the amount of surfactant is from about 1 to 50% based on the total weight of the composition. Normally, the amount of surfactant will depend on the amount of AAC. A preferred ratio of AAC to surfactant is from about 1:0.3 to 1:10. The final use concentration of the AAC, i.e., after dilution, depends on the particular AAC. However, it is important that upon dilution, the diluted form remain stable for a time period sufficient to allow it to be applied. This, of course, will vary with the schedule for the application in the field or end user. A preferred end-use microemulsion composition in accordance with the invention composition comprises from about 0.005 to 1 weight percent of the AAC, from about 1 to 15 weight per¬ cent of the lactam, from about 0.01 to 10 weight percent of the surfactant(s) , and the remainder water. With the inventive microemulsion, prolonged stability obtained, and formulations in a ready-to-use format can be provided for consumer use. Conventional adjuvants may also be added to the inventive composition, e.g., film forming polymers, i.e., polyvin lpyrrolidone, viscosity modifiers, and the like, so long as they do not destroy or adversely affect the microemulsive state. The following examples illustrate the present invention * : Experimental Procedure: A. Formulations: Formulations were prepared by weighing and mixing the exact proportions of the ingredients. Typically 100 g samples of the water-based formulations were prepared for each evaluation in 4 oz. stoppered bottles. When a lactam was used, the AAC was dissolved completely in the measured quantity of the lactam. The surfactant(s) was added to the AAC or to the solution of the AAC in the lactam (if a lactam was used) . The contents were mixed in an automatic orbital shaker until the AAC dissolved completely or the * In the examples, all compositional percentages are percent by weight of the total composition unless otherwise indicated. mixture became homogeneous. Normally, this took about thirty minutes. A concentrate was then obtained which was either diluted immediately or stored. In those instances where the concentrate was stored for a period of time from 4 hours to two weeks and then diluted with water, this fact is indicated in the tabular results. The water-based microemulsions were prepared by ' adding the required quantity of the concentrate to water. The dilution water was either deionized water or World Health organization (WHO) standard hard water of hardness of 342 ppm expressed as CaC03 equivalent. B. Evaluation of Stability The samples were visually examined for clarity, precipitation, and separation or turbidity at ambient temperatures. Stable formulations were observed for as long as six months. The formulations were considered stable if they remained clear by visual observation for more than 4 days. Formulations that became cloudy or separated within 24 hours were considered unstable. However, certain .AAC's are known to be unstable under certain conditions, for example, they may hydrolyze in water, e.g., Hydramethylnon, Carbaryl, and the like. Ac¬ cordingly, stability of the microemulsion for such an AAC must be judged using a different standard from AAC's which are not subject to such chemical instability. Generally, for such a compound, stability of four hours is considered satisfactory since the diluted material would as a practi¬ cal matter have to be used shortly after dilution. In these instances, we have found indications that the inventive microemulsion increase the chemical stability of the AAC. Promising formulations were evaluated for stability at lower and higher temperatures in the range from 10°C through 45°C. Samples were stored at fixed temperatures of 10"C through 45°C and were observed visually as a function of time. In a few cases, the clarity was also measured instrumentally and expressed as NTU (Nephelometric turbidi¬ ty units) using a Hach Ratio Turbidimeter. Samples with values <50 NTU were considered visually clear. In the following tables, the last recorded visual observation represents the last time period that a visual observation was made, e.g., if the last observation shown is for the two week period, no further observations were made for that run. Also, in those runs indicating a hiatus between two identical observations, interim observations were the same as those indicated before and after the hiatus, e.g., for Run No. 1, the sample was "cloudy" for 1 day, 2 days, and 4 days; and for Run No. 6, the sample was clear for 1 day, 2 days, and 4 days. EXAMPLE I TABLE 1 h, means 342 ppm standard hard water; d, means deionized water. T.ABLE 1 (continued) *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 1 (continued) *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 1 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 1 (continued) *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 1 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ♦ ) h, means 342 ppm stand.ard hard water; d, means deionized water. TABLE 2 (continued) h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ♦ vl means viscous liquid; tp means two phases *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 2 (continued) ppm standard hard water; d, means deionized water. TABLE 3 h, means 342 ppm standard hard water; d, means deionized water. TABLE 3 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 3 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. ♦ ) h, me-ans 342 ppm standard hard water; d, means deionized water. TABLE 4 h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) * ■ ) h, means 342 ppm standard hard water; d, means deionized water. ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) *") h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) h, means 342 ppm standard hard water; d, means deionized water. TABLE 4 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. T.ABLE 5 h, means 342 ppm standard hard water; d, means deionized water. TABLE 5 (continued) *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 5 (continued) * ph was monitored for 1 week, no appreciable change pH @ 4.6 ♦ ) h, me-ans 342 ppm standard hard water; d, means deionized water. TABLE 5 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. h, means 342 ppm standard hard water; d, means deionized water. ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 5 (continued) pH was monitored for 1 week, no appreciable change pH @ 4.4 h, means 342 ppm standard hard water; d, means deionized water. TABLE 5 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) h, means 342 ppm standard hard water; d, means deionized water. fc ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (Continued) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) *) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 fcontinued) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 6 (continued) ♦ ) h, means 342 ppm standard hard water; d, means deionized water. T.ABLE 7 ♦ ) h, means 342 ppm standard hard water; d, means deionized water. T.ABLE 8 ♦ ) h, means 342 ppm standard hard water; d, means deionized water. TABLE 8 h, means 342 ppm standard hard water; d, means deionized water. T.ABLE 8 (continued) * supernatant colored ♦ ) h, means 342 ppm standard hard water; d, means deionized water. EXAMPLE II EXPERIMENTAL SECTION A. Determination of Solubilities of AAC A weighed quantity of the AAC was stirred with 10 g of the chosen solvent in an automatic orbital shaker for 30 minutes, starting with 0.1-1 g of AAC, depending upon its solubility. Incremental amounts of AAC (0.1 g) were added until there was no dissolution after 30 minutes stirring. The highest limit of solubility was thus ob- tained. Incremental amounts of solvents (0.1 g) were then added until a solution was formed; the lower end of solu¬ bility was thereby obtained. All determinations were made at ambient conditions -20 -25°C. Results from these tests are shown in Table 9. RESULTS AND DISCUSSION Solubilities of carbaryi in N-alkylpyrrolidones as well as four other solvents are shown in Table 9. All measurements made at 25°C unless otherwise specified. For * see "The Agroσhemical Handbook", 2nd Ed. Royal Soc. of Che . , The University of Nottingham NG72RD, England (1987) . Stable Microemulsion for Carbaryi Since carbaryi is a well-known active ingredient, both physical and chemical stability of the microemulsion of the composition of Table 10 was monitored. The pH of this formulation (Table 10) was moni¬ tored with time. The UV spectra of solutions at -30 ppm AAC in EtOH prepared by appropriate dilution of the for u- lation (1/100) with ethanol was obtained as a function of time. The change in UV absorption was used to determine the decrease in carbaryi concentration based on a calibra¬ tion curve previously obtained. 16 percent loss was noticed in 40 days via UV spectra data. The pH of the formulation was also alkaline throughout the duration. A drop in pH from 9.27 to 7.4 (40 days) was observed. The formulation further deteriorated on standing beyond 40 days. Since carbaryi is known to hydrolyze in alkaline medium (see-the Agrochemical Handbook), the formulation was • buffered by the addition of the appropriate quantity of KH 2 P0 4 . The buffered formulation, buffered at pH = 6, did not show any decay in the UV absorbance at λ max = 279 nm observed after a period of 30 days. However, tiny crystals of carbaryi stared separating on the 11th day. Microscopic examination showed tiny needles, 50 microns long. The original formulation was buffered by adding a trace of Gafac RE-610 (<0.1 g to 100 g of formulation) instead of KH 2 P0 4 to bring the pH to 6. The resulting formulation was found stable for 120 days without any separation of crystals, and showed no appreciable decay in the UV absorbance. Figs. 1, 2 and 3 show microphotographs at 250x of a droplet from the formulation without buffering, the

Claims: formulation buffered with KH 2 P0 4 , and the formulation buffered with Gafac RE-610, respectively, after 131 days. As shown, a substantial reduction in crystal formation was observed with the system buffered with the hydrophobic buffering agent. Example III A series of microemulsions and concentrates having the composition shown in Table 11 was prepared. Each of the compositions was identical except for the amount of glycerol present. Formulation No. 1 was unstable at 2-3°C. In contrast, formulations No. 2 and # 3 were observed to be clear from precipitation for six months at 2-3°C. No substantial difference in stability at storage up to 35°C was observed. Formulations 2, 3, and 4 showed no precipitation when stored at 2 - 3°C for six months. Formulation 1 produced crystals in less than 48 hours at 2 - 3°C. Cold stability was not observed when propylene glycol, butanol, butene diol and isopropanol were substituted for glycerol. TABLE 11 MICROEMULSION COMPOSITIONS WHAT IS CLAIMED IS : 1. A composition comprising: (a) a water insoluble agriculturally active ingredient; (b) a surfactant; (c) a lactam having the formula: wherein R is hydrogen or a branched or straight- chained alkyl having from 1 to 16 carbon atoms, R 1 is a branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R 1 is less than or equal to 16; and n is 3, 4, or 5; and (d) at least about 80% by weight water; wherein the identity and amounts of components a, b, c, and d are such that said composition is in the form of a microemulsion. 2. The composition of claim 1 wherein the lactam is an alkyl pyrrolidone having the formula: wherein R is hydrogen or a linear or branched alkyl having from 1 to 16 carbon atoms and , is a linear or • branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R 1 must be less than or equal to 16. 3. The composition of claim 2 wherein R is hydrogen and R 1 is methyl, ethyl, butyl, octyl, iso-octyl or dodecyl. 4. The composition of claim 1 wherein the lactam is N-methyl pyrrolidone, N-octyl pyrrolidone, N-iso- octyl pyrrolidone, or N-dodecyl pyrrolidone. 5. A composition comprising: (a) a water insoluble agriculturally active ingredient; (b) a surfactant; (c) a lactam having the formula: wherein R is hydrogen or a branched or straight- chained alkyl having from 1 to 16 carbon atoms, R 1 is a branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R 1 is less than or equal to 16; n is 3, 4, or 5; and d) 0 percent water; wherein the identity and amount of compositions a, b, c, are such that upon the admixing of water in an amount of at least about 80% by weight with the composition, a microemulsion is formed. 6. The * composition of claim 5 wherein the lactam is an alkyl pyrrolidone having the formula: wherein R is hydrogen or a linear or branched alkyl having from 1 to 16 carbon atoms and R 1 is a linear or branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R 1 must be ' less than or equal to 16. 7. The composition of claim 6 wherein R is hydrogen and R t is methyl, ethyl, butyl, octyl, iso-octyl, or dodecyl. 8. The composition of claim 6 wherein the lactam is N-methyl pyrrolidone, octyl pyrrolidone, N-iso- octyl pyrrolidone, or N-dodecyl pyrrolidone. 9. The composition of claim 5 wherein the concentration of component (a) is in excess of 5 weight percen . 10. The composition of claim 5 wherein the concentration of component (a) is in the range from about 5 to 25 percent by weight. 11. The composition of claim 5 wherein the amount of component (b) is from about 1 to 50% by weight of the total composition. 12. The composition of claim 5 wherein the ratio of component (a) to component (b) is from about 1:0.3 to 1:10. 13. A method for the preparation of a microemulsion containing an agriculturally active ingredi¬ ent comprising admixing water in an amount of at least 80% by weight based on the total weight of the mixture with the composition of claim 5. 14. A method for treating crops comprising contacting the crops with an agriculturally effective amount of the composition of claim 1. 15. A method for controlling pests comprising contacting the pests with a pest controlling effective amount of the composition of claim 1. 16. The composition of claim 1 wherein the water insoluble agriculturally active ingredient is unstable due to hydrolysis when in contact with water, and the composi¬ tion further contains a buffering effective amount of a hydrophobic acid. 17. The composition of claim 16 wherein the hydrophobic acid is selected from the group consisting of those having a pKa of from about 2 to 5. 18. The composition of claim 17 wherein the hydrophobic acid is present in an amount form about 0.01 to 20 percent by weight, based on the total weight of the mixture in the end-use formulation. 19. A composition comprising: (a) a water insoluble agriculturally active ingredient which exhibits instability due to hydrolysis when added to water; (b) a surfactant; (c) a lactam having the formula: wherein R is hydrogen or a branched or straight chained alkyl having from 1 to 16 carbon atoms, R,, is a branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R 1 is less than or equal to 16; n is 3, 4, or 5; and (d) a buffering effective amount of a hydropho¬ bic acid; and (e) 0 percent water; wherein the identity and amount of components a, b, c, and d, are such that upon the admixing of water in an amount of at least about 80% by weight with the composition, a micro¬ emulsion is formed. 20. The composition of claim 19 wherein the lactam is an alkyl pyrrolidone having the formula: wherein R is hydrogen or a linear or branched alkyl having from 1 to 16 carbon atoms and R 1 is a linear or branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R,, must be less than or equal to 16. 21. The composition of claim 19 wherein R is hydrogen and R 2 is methyl, ethyl, butyl, octyl iso-octyl, or dodecyl. 22. The composition of claim 19 wherein the lactam is N-methyl pyrrolidone, octyl pyrrolidone, N-iso- octyl pyrrolidone, or N-dodecyl pyrrolidone. 23. The composition of claim 19 wherein the agriculturally active ingredient is selected from the group consisting of cyclo compounds, carbamates, synthetic pyrethroids; diphenyl compounds, non-phosphates, organic ' phosphates, thiophosphates, and dithiophosphates. 24. The composition of claim 19 wherein the hydrophobic acid is selected from the group consisting of those having a pK a of from about 2 to 5. 25. The composition of-claim 19 wherein the hydrophobic acid is present in an amount from about 0.01 to 20 percent by weight, based on the total weight of the mixture in the end-use formulation. 26. A method for the preparation of a microemul¬ sion containing an agriculturally active ingredient com¬ prising admixing water in an amount of at least 80% by weight based on the total weight of the mixture with the composition of claim 19. 27. A method for the preparation of a microemulsion containing an agriculturally active ingredi- ent comprising admixing water in an amount of at least 80% by weight based on the total weight of the mixture with the composition of claim 19. 28. The composition of claim 1 which further comprises a cold temperature stabilizing effective amount of a polyhydric alcohol. 29. The composition of claim 28 wherein the lactam is an alkyl pyrrolidone having the formula: wherein R is hydrogen or a linear or branched alkyl having from 1 to 16 carbon atoms and R,, is a linear or branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R., must be less than or equal to 16. 30. The composition of claim 28 wherein the lactam is N-octyl pyrrolidone, N-iso-octyl pyrrolidone, or N-dodecyl pyrrolidone. 31. The composition of claim 28 wherein the agriculturally active ingredient is selected from the group consisting of cyclo compounds, carbamates, synthetic pyret¬ hroids, diphenyl compounds, non-phosphates, organic phos¬ phates, thiophosphates, and dithiophosphates. 32. The composition of claim 28 wherein the polyhydric alcohol is selected from the group consisting of glycerol, pentaerythritol, mannitol and sorbitol. 33. The composition of claim 28 wherein the polyhydric alcohol is present in an amount from about 2 to 50 percent by weight, based on the total weight of the mixture in the end-use formulation. 34. A composition comprising: (a) a water insoluble agriculturally active ingredient which exhibits instability due to hydrolysis when added to water; (b) a surfactant; (c) a lactam having the formula: wherein R is hydrogen or a branched or straight chained alkyl having from 1 to 16 carbon atoms, R t is a branched or straight chained alkyl having from 1 to 16 carbon atoms, with the provision that the sum of the carbon atoms in R and R 1 is less than or equal to 16; n is 3, 4, or 5; and (d) a cold temperature stabilizing effective amount of a polyhydric alcohol; (e) 0 percent water; wherein the identity and amount of compositions a, b, c, are such that upon the admixing of water in an amount of at least about 80% by weight with the composition, a microemu¬ lsion is formed. 35. The composition of claim 34 wherein the lactam is an alkyl pyrrolidone having the formula: wherein R is hydrogen or a linear or branched alkyl having from 1 to 16 carbon atoms and R 1 is a linear or branched alkyl having from 1 to 16 carbon atoms, with the provision that the sum of number of carbon atoms in R and R 1 must be less than or equal to 16. 36. The composition of claim 28 wherein the lactam is N-methyl pyrrolidone, octyl pyrrolidone, N-iso- octyl pyrrolidone, or N-dodecyl pyrrolidone. 37. The composition of claim 30 wherein the amount of component (a) is in excess of 5 weight percent, and the amount of component (b) is from about 1 to 50% by weight of the total composition. 38. The composition of claim 31 wherein the concentration of component (a) is in excess of 5 weight percent. 39. The composition of claim 34 wherein the polyhydric alcohol is selected from the group consisting of glycerol, pentaerythritol, mannitol and sorbitol.

Inventors: CHAUDHURI RATAN K, DAHANAYAKE MANILAL, NARAYANAN KOLAZI S, CHAUDHURI, RATAN, K., DAHANAYAKE, MANILAL, NARAYANAN, KOLAZI, S.
Applicants: ISP INVESTMENTS INC, ISP INVESTMENTS INC.
Application year: 1992
Main classification: A01N57
IPC codes: A01N25, A01N31, A01N43, A01N53, A01N57