Use of a combination of a gel and a solution, both containing an organic acid for cleaning dentures

Abstract: The invention relates to the use of a combination of a gel and a solution, both containing an organic acid, in particular natural biological organic acids, for cleaning dentures, as well as to a kit which contains such a gel as well as such a solution, both containing surface-active substances, aroma substances and preservatives. Thickeners may also be included in the preparations. The combination of preparations according to the invention has an action which is at least as good as the effervescent preparations according to the state of the art.

Description: The invention relates to the use of a combination of a gel and a solution, both containing an organic acid for cleaning dentures. Cleaning agents for dentures are known. Such known agents frequently contain aggressive chemicals such as hypochlorite, perborate or persulphate. A disadvantage of such chemicals is that the quality of the denture material deteriorates. As a consequence, the denture suffers discolourations and damage. It has been found, surprisingly, that when using a combination of a gel and a solution, containing an organic acid for cleaning, such disadvantages do not arise. In this connection it is to be noted that the cleaning agents used according to the invention, i.e. the gel and the solution, are principally based on an organic acid, in particular on natural biological organic acids, but that in addition to these, additives can be present, such as surface-active substances, thickeners, aroma substances, i.e. perfume(s) and/or flavourings, and preservatives. The proviso is that the cleaning agents do not contain aggressive chemicals such as persulphate and perborate. It is noted that European Patent Application 0360299 discloses effervescent preparations for cleaning dentures. Such preparations contain a hypochlorite-producing agent and an effervescing agent, in which is included a hypochlorite-deactivating agent. The effervescing agent consists, for example, of a mixture of an alkali metal bicarbonate and a water-soluble organic acid such as citric acid, ascorbic acid and tartaric acid. The function of such acids is thus to regulate the effervescing action. The invention also encompasses the making-up of the single non-effervescent preparations for cleaning dentures, i.e. the gel and the solution, as well as a kit containing a combination of said preparations. In particular, organic acids chosen from among the natural biological acids are used according to the invention. Natural biological organic acids can be defined as organic acids occurring in nature. These are generally water-soluble. Examples of natural biological organic acids are: acetic acid, pyruvic acid, citric acid, malic acid, (cis)aconitic acid, fumaric acid, succinic acid, (iso)citric acid, amino acids, formic acid, ascorbic acid, oxalic acid, tartaric acid, mandelic acid, ketoglutaric acid, benzoic acid, propionic acid etc. The invention also relates to a preparation for cleaning dentures, wherein the active substance comprises at least one organic acid which is preferably chosen from among the natural, biological acids which are defined above. In the use according to the invention, and in the preparations or kit according to the invention, the organic acid is preferably citric acid. Compared to the known agents for cleaning dentures, the combination or kit according to the invention has at least an equally good action. In the use and in the kit according to the invention the gel can comprise: 0.01-10% by weight, preferably 0.1-1% by weight, of organic acid, 0-20% by weight, preferably 5-10% by weight, of surface-active substance, 0-10% by weight, preferably 2-5% by weight, of thickener, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance and 0-4% by weight, preferably 0.01-0.1% by weight, of preservative, the remainder being water; and the liquid can comprise: 0.01-25% by weight, preferably 8-16% by weight, of organic acid, 0-20% by weight, preferably 2-5% by weight, of surface-active substance, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance and 0-4% by weight, preferably 0.01-0.1% by weight, of preservative, the remainder being water. Though citric acid is preferably used as the organic acid in the invention, other acids, such as those mentioned above, in particular tartaric acid, acetic acid and formic acid, can equally well be used. As surface-active substances which in addition to the surface-active action possess a thickening, suspending and stabilising action there may be mentioned: anionic detergents in general, as well as fatty alcohol(ether)-sulphates and -sulphosuccinates, lauryl ether-sulphate, lauryl sulphate, alkylsulphonates and ethoxylated alkyl polyglycol ethers. Further examples are sodium lauryl-sulphate, monoethanolammonium lauryl-sulphate, sodium ethylhexyl-sulphate and lauryl fatty alcohol sulphosuccinate. As thickeners which serve to thicken and/or to gel the preparation, there may be used electrolytes, for example inorganic salts such as sodium chloride, but also cellulose derivatives and gelatin or gelatin-like substances. As aroma substances, there may be mentioned perfumes or eucalyptus or similar aroma substances. As preservatives, there may be mentioned the commercially available product Euxyl/K 100, which consists of 5-chloro-2-methyl-3-(2H)-isothiazolone, 2-methyl-3(2H)-isothiazolone, together with magnesium chloride/magnesium nitrate and benzyl alcohol. The invention also relates to a method for cleaning dentures with the use of the kit or combination as defined in the above. The examples which follow illustrate the various possibilities of the preparations according to the invention. Cleaning liquid Formulation 1 Minimum Optimum Maximum citric acid 6 % by weight 12.0 % by weight 25 % by weight lauryl ether sulphate 2 % by weight 3.5 % by weight 5 % by weight sodium chloride 2.5 % by weight 3.5 % by weight 5 % by weight eucalyptus 0.5 % by weight 0.5 % by weight 0.5 % by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 2 Minimum Optimum Maximum tartaric acid 6 % by weight 12.0 % by weight 25 % by weight lauryl ether sulphate 2 % by weight 3.5 % by weight 5 % by weight sodium chloride 2.5 % by weight 3.5 % by weight 5 % by weight eucalyptus 0.5 % by weight 0.5 % by weight 0.5 % by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 3 Minimum Optimum Maximum acetic acid 7 % by weight 12.0 % by weight 20 % by weight lauryl ether sulphate 2 % by weight 3.5 % by weight 5 % by weight sodium chloride 2.5 % by weight 3.5 % by weight 5 % by weight eucalyptus 0.5 % by weight 0.5 % by weight 0.5 % by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 4 Minimum Optimum Maximum formic acid 6 % by weight 12.0 % by weight 25 % by weight lauryl ether sulphate 2 % by weight 3.5 % by weight 5 % by weight sodium chloride 2.5 % by weight 3.5 % by weight 5 % by weight eucalyptus 0.5 % by weight 0.5 % by weight 0.5 % by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Cleaning gel Formulation 5 citric acid 0.4 % by weight 0.6 % by weight 2.0 % by weight lauryl ether sulphate 8.0 % by weight 11.0 % by weight 15.0 % by weight thickener/common salt 2.5 % by weight 3.5 % by weight 3.5 % by weight perfume/eucalyptus 0.05% by weight 0.05% by weight 0.05% by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 6 tartaric acid 0.4 % by weight 0.6 % by weight 2.0 % by weight lauryl ether sulphate 8.0 % by weight 11.0 % by weight 15.0 % by weight thickener/common salt 2.5 % by weight 3.5 % by weight 3.5 % by weight perfume/eucalyptus 0.05% by weight 0.05% by weight 0.05% by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 7 acetic acid 0.4 % by weight 0.6 % by weight 2.0 % by weight lauryl ether sulphate 8.0 % by weight 11.0 % by weight 15.0 % by weight thickener/common salt 2.5 % by weight 3.5 % by weight 3.5 % by weight perfume/eucalyptus 0.05% by weight 0.05% by weight 0.05% by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Formulation 8 formic acid 0.4 % by weight 0.6 % by weight 2.0 % by weight lauryl ether sulphate 8.0 % by weight 11.0 % by weight 15.0 % by weight thickener/common salt 2.5 % by weight 3.5 % by weight 3.5 % by weight perfume/eucalyptus 0.05% by weight 0.05% by weight 0.05% by weight Euxyl/K100 0.02% by weight 0.02% by weight 0.02% by weight Minimum = the first detectible cleaning effect Optimum = the optimum cleaning effect without damage occurring to the denture material Maximum = the limit, at which damage to the denture material by the active substance of the preparation can no longer be ruled out. The effectiveness of the preparations according to the invention was determined in accordance with the following Instruction: Instruction Soiling of dentures The dentures were soiled with the following products: red wine, tartar, coffee, tea, nicotine and lipstick. Prepare a saturated solution of tartar and add sufficient red wine, strong coffee and strong tea, so that the denture can be entirely submerged therein. Put the denture into this solution for 10 minutes and let the denture dry at a temperature of 40°C. Blow cigarette smoke over the denture for 15 minutes and thereafter smear the denture with red lipstick. Repeat this procedure five times. Cleaning of the dentures with gel The denture is cleaned by means of a denture brush and the gel, as prescribed. Cleaning of the dentures with the aid of a liquid preparation The denture is placed for 8 hours in a solution, diluted 1:4, of the preparation. Assessment of cleaning After cleaning, the denture is inspected visually with attention to colour, smoothness and odour. It was found that the non-effervescent preparations according to the invention, which are described above, possess an excellent cleaning action in tests according to the Instruction. This action is at least as good as that of preparations according to the state of the art.

Claims: Use of a combination of a gel and a solution, both containing an organic acid for cleaning dentures. Use according to Claim 1, wherein the organic acid is chosen from among the natural biological organic acids, in particular citric acid. Use according to Claims 1 or 2 wherein the gel comprises: 0.01-10% by weight, preferably 0.1-1% by weight, of organic acid, 0-20% by weight, preferably 5-10% by weight, of surface-active substance, 0-10% by weight, preferably 2-5% by weight, of thickener, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance, 0-4% by weight, preferably 0.01-0.1% by weight, of preservative; and further water; and the liquid comprises: 0.01-25% by weight, preferably 8-16% by weight, of organic acid, 0-20% by weight, preferably 2-5% by weight, of surface-active substance, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance, 0-4% by weight, preferably 0.01-0.1% by weight, of preservative, and further water. Kit for cleaning dentures at least comprising a gel and a solution both containing an organic acid. Kit according to Claim 4, wherein the organic acid is chosen from among the natural biological organic acids, in particular citric acid. Kit according to Claim 4 or 5, wherein the gel comprises: 0.01-10% by weight, preferably 0.1-1% by weight, of organic acid, 0-20% by weight, preferably 5-10% by weight, of surface-active substance, 0-10% by weight, preferably 2-5% by weight, of thickener, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance, 0-4% by weight, preferably 0.01-0.1% by weight, of preservative; and further water; and the liquid comprises: 0.01-25% by weight, preferably 8-16% by weight, of organic acid, 0-20% by weight, preferably 2-5% by weight, of surface-active substance, 0-1% by weight, preferably 0.01-0.1% by weight, of aroma substance, 0-4% by weight, preferably 0.01-0.1% by weight, of preservative, and further water. A method for cleaning dentures using the kit according to any of Claims 4-6.

Inventors: ADAMS MARC INIGO, ADAMS, MARC INIGO
Applicants: DENTIP INT BV, DENTIP INTERNATIONAL B.V.
Application year: 1992
Main classification: A61K7
IPC codes: A61Q11, A61K8