Reagent feeder

Abstract: This invention is intended to provide a reagent feeder which can to be used in both a finger-push system and a slide system by only attaching and detaching a simple auxiliary component to and from a case body depending on a state of operation or a preference of operator. The feeder includes the case body (1), a sphere discharge port (5) and a discharge device (10), so as to discharge a sphere one by one by pushing down the discharge device (10). The discharge device (10) is provided with an operation lever (25) which extends out of the case body and can be pushed down by finger. A slide cover (30) surrounding an outer periphery of the case body (1) is attached to the case body (1) in such a way that it can be moved freely in a vertical direction and can be detached from the case body, and the slide cover (30) is engaged with the operation lever (25) of the discharge device (10) so that it can be moved integrally with the discharge device (10).

Description: This invention relates to a reagent feeder for charging a fixed quantity of reagent into a specimen such as blood or urine collected in a test tube etc., and particularly to a reagent feeder appropriate for charging a fixed quantity of reagent into a number of specimens in order respectively. In case when reagents are charged into a number of specimens of fixed quantity and inspect them respectively, it is required that a quantity of reagent in each test tube must be uniform in order to get exact inspection results. It is extremely difficult to supply a very small and fixed quantity of reagent in every test tube by using a pipet etc., so that the exact inspection results can not be expected. In order to cope with the above-mentioned requirement, there are developed various reagent feeders accomplishing the exact feeding of fixed quantity of reagent, in which a fixed quantity of reagent is forced to adhere to a sphere made of synthetic resin etc. having a definite standard and many of spheres are housed in a case, so that the sphere is charged in each specimen one by one. For example, there are disclosed JP-A- 62-24147, JP-U-61-6446, FR-A-2 643 881, and FR-A-2 641 764. Operation is simple in the finger-push system of the above former proposal. In case of a great many number of specimens, however, fingers of operator are extremely fatigued so that continuous operation becomes impossible, because operation load is concentrated on his fingers. In the case-slide system of the above later proposal, the operator's fingers will be less fatigued and the system is apt to be well-adapted to operation of the great many number of specimens because the entire case is gripped by his hand. However, since the lower end discharge port is pushed upon a port of test tube etc., the operation will sometimes become difficult when the test tube etc. is installed in an unstable position. Thus, it cannot be decided unconditionally which system is sufficiently good, because the suitability of each discharge system differs depending on the number of specimen or the state of test tube etc. in which the specimen is put, or a preference of operator. Therefore, it is preferable to prepare all of the above reagent feeders and select a most suited reagent feeder from them as occasion demands. However, this way is uneconomical because of much waste in cost and control. An object of the invention is to provide a reagent feeder which can be used as both a finger-push system and a slide system by only attaching and detaching a simple auxiliary component to and from a case body depending on a state of operation or a preference of operator. This object is solved with the features of the claims. (Operation) When the feeder is to be used in the finger-push system, the slide cover should be removed from the case body. That is; the case body is gripped, the lower end discharge port is brought to a position of port of test tube etc., the operation lever is pushed down by the finger. Thus, one sphere to which the reagent adheres can be charged in the test tube. When the feeder is to be used in the slide system, the slide cover is attached to the case body and simultaneously engaged with the operation lever. That is; the slide cover is gripped, the lower end discharge port is pressed against the port of test tube etc., and the slide cover is pushed down. Thus, one sphere to which the reagent adheres can be charged in the test tube. As described above, the present invention includes the following advantages: (1) In the reagent feeder for feeding the sphere to which a fixed quantity of reagent adheres to each specimen one by one, the operation lever operated by finger is installed thereon as a means for operating the discharge device to send and discharge the reagent one by one, and the slide cover which engages with the operation lever so as to move together with the operation lever, is attached to the case body in the freely attachable and detachable way. Therefore, the feeder can be easily changed to a discharge system suitable for respective conditions by only attaching or detaching the slide cover according to the quantity of specimen, the installation stability of test tube etc. or the preference of operator, so that a practical effect of the feeder is large. (2) Since the case can be used as it is when the application mode is changed between the finger-push system and the slide system, it becomes unnecessary to prepare the all types of reagent feeders so that the feeder of the present invention is preferable from the standpoint of cost and control. Fig. 1 is a front view of the reagent feeder according to the present invention. Fig. 2 is a side view (viewed in a direction of arrow II) of Fig. 1. Fig. 3 is an enlarged sectional view taken on a line III-III of Fig. 1. Fig. 4 is an enlarged sectional view taken on a line IV-IV of Fig. 2. Fig. 5 is a partial sectional view showing a state where a sphere is discharged. Fig. 6 is a front view of a state where a slide cover is removed. Fig. 7 is a side view of a state where a slide cover is removed. Fig. 8 is a sectional view showing another embodiment of the slide cover. Fig. 1 through Fig. 7 show an example of the reagent feeder according to the present invention. Fig. 1 through Fig. 5 show the state where the feeder is used in the slide system, and Fig. 6 and Fig. 7 show the state where the feeder is used in the finger-push system. In Fig. 6 and Fig. 7, a case body 1 is made of transparent synthetic resin etc. and formed into a vertically long and flat box-shape, and integrally has a cylindrical hopper 3 on its upper portion. A cover 2 is placed on top of the hopper 3 in a freely attachable and detachable. An operation lever 25 movable in vertical direction extends from an inside of the case body 1 to its surface side, and a tongue 25a for pushing down the operation lever 25 is formed integrally on it. Fig. 4 is the enlarged sectional view taken on the line IV-IV of Fig. 2. The case body 1 has a sphere housing chamber 4 at a lower portion of the hopper 3 and includes a downward opening discharge port 5 at a left end in the figure on its bottom end. A bottom wall 7 of the sphere housing chamber 4 inclines downward to its left side and the chamber includes a connecting port 4a at its left bottom end. A lateral-trapezoidal or snaking sphere guide passage 8 is formed between the connecting port 4a and the discharge port 5, the sphere guide passage 8 has a sectional area for drawing up the spheres in line and for passing them, and a projection 17 for stopping a sphere A1 is integrally formed on a terminal portion of the guide passage. A discharge device 10 for releasing the sphere one by one is formed long in the vertical direction and arranged freely movably in the vertical direction along a left wall surface in the case body 1, and a bottom edge of the discharge device 10 comes up to an upper end of the discharge port 5. An engaging projection 13 fronting on the lower end projection 17 of the sphere guide passage 8 is formed thereat, and a sphere A1 situated at a position immediately before the discharge port is stopped by the both projections 13 and 17. A shutter surface 15 is formed on an upper part of the projection 13 through an L-shaped portion, and the shutter surface 15 comes into and withdraws from the terminal portion of the guide passage 8 according to a vertical movement of the discharge port 10 so as to open and close the terminal portion of the guide passage 8. A spring receiver 16 is integrally formed on an upper portion of the shutter surface 15, and a return spring 21 is compressedly installed between the spring receiver 16 and a case body 1 side lower spring receiver 20. The return spring 21 urges the discharge device 10 upward, and the discharge device 10 is held at a waiting position shown by Fig. 4 when the spring receiver 16 comes in contact with a case-body side stopper 19. 22 denotes a guide pin. As described above, the operation lever 25 formed integrally on the upper end of the discharge device 10 extends to the case body surface side passing through a guide lever hole 24 of the case body 1. The lever is bent to a central side of the case body and integrally has the foregoing tongue 25a at its tip end. In Fig. 3, a slide cover 30 for changing from the finger-push system to the slide system is made of transparent synthetic resin and has a two-block construction including a front cover member 30a and a rear cover member 30b, and the both cover members 30a and 30b have a flat U-shaped cross section. The both cover members 30a and 30b are mated each other at their opening edges and connected together by screws 31 at four corners, so as to be formed into a cylindrical shape having a rectangular cross section. Thereby, the cover can encase an outer periphery of the case body 1 in such a manner as freely attachable and detachable and freely movable in the vertical direction. A convex portion 23 able to house the operation lever 25 is formed on the front cover member 30a, an engaging hole 27 with which the tongue 25a of the operation lever 25 engages is formed on the convex portion 23, and the slide cover 30 can be moved together with the discharge device 10 in the vertical direction when the tongue 25a engages with the engaging hole 27. In order to use the feeder in the finger-push system, the slide cover 30 should be disassembled and removed from the case body 1 prior to use as illustrated by Fig. 7. Naturally, a large number of spheres may be housed in the case body 1 from the upper hopper 3 prior to use. Under this state, the case body 1 is gripped, the discharge port 5 is brought to the position of port of test tube etc., and the tongue 25a of the operation lever 25 is pushed down. Then, the entire discharge device 10 of Fig. 4 comes down against the return spring 21, so that the sphere Al stopped by the projection 13 is released and discharged into the test tube from the discharge port 5 as shown by Fig. 5. At the same time, the shutter surface 15 closes the terminal portion of the guide passage 8 to prevent the next sphere A2 from moving to the upper end of the discharge port 5. After completion of supplying the sphere, the discharge device 10 is lifted up by the return spring 21 when the finger is released from the tongue 25a. Thereby, the shutter surface 15 opens the guide passage 8, and the next sphere A2 is fed to the projections 13 and 17 so as to return to the state same as Fig. 4. In order to use the feeder in the slide system, the slide cover members 30a and 30b should be put on the case body 1 from both front and rear sides as illustrated in Fig. 1 and Fig. 2, the tongue 25a of the operation lever 25 should be engaged with the engaging hole 27 of the front cover member 30a, and the both members 30a and 30b should be fastened by plural screws 31. When using the feeder, the slide cover 30 is gripped by hand, the lower edge of the discharge port 5 is pressed upon the upper end of the test tube etc., and the discharge device 10 is pressed down by pushing down the slide cover 30 itself relative to the case body 1. Thereby, one sphere can be released as shown by Fig. 5, and the state of Fig. 4 is restored by returning the slide cover 30 upward. Fig. 8 shows another embodiment of the slide cover 30. A pair of cover members 30a and 30b are formed integrally so as to be freely opened and closed through a hinge 34, and are so constructed that they can be closed into a box-shape by means of a stopper mechanism 40 composed of a projection 33 and a concave portion 32.

Claims: A reagent feeder comprising a case body (1) housing a plurality of spheres to which reagents adhere, a sphere discharge port (5) formed at a bottom portion of the case body (1), and a discharge device (10) supported in the case body (1) freely movably in a vertical direction and urged to an upper waiting position by an elastic means (21), the discharge device (10) stopping a sphere (A1) situated at a position immediately before the discharge port (5), discharging only the above-mentioned sphere (A1) to the discharge port (5) when the discharge device (10) is pushed downward, and sending out the next sphere (12) to the position immediately before the discharge port (5) when the discharge device (10) is returned to the upper waiting position; characterized in that the discharge device (10) is housed within the case body (1) even when pushing down an operation lever (25) formed on the discharge device (10) and extending outwards through an upper side part of the case body (1) to allow a push-down operation by finger, a slide cover (30) surrounding an outer periphery of the case body (1) is attached to the case body (1) in such a way that it can be moved freely in the vertical direction and can be detached from the case body (1), and the slide cover (30) is engaged with the operation lever (25) of the discharge device (10) so that it can be moved integrally with the discharge device (10). A reagent feeder as set forth in claim 1, in which the case body (1) and the slide cover (30) are made of transparent synthetic resin. A reagent feeder as set forth in claim 1 or claim 2, in which the slide cover (30) is formed into a two-block construction comprising a front slide cover member (30a) and a rear slide cover member (30b). A reagent feeder as set forth in claim 3, in which both cover members (30a,30b) are formed integrally so as to be opened and closed through a hinge (34) and can be closed by means of a stopper mechanism (40).

Inventors: MATSUSHIMA HIROAKI, TOBIKI HISAO, MATSUSHIMA, HIROAKI, TOBIKI, HISAO, Matsushima, Hiroaki, c/o Takarazuka factory, Tobiki, Hisao, c/o Takarazuka factory
Applicants: NIHON MEDIPHYSICS CO LTD, NIHON MEDI-PHYSICS CO., LTD.
Application year: 1992
Main classification: G01N33
IPC codes: B65G47, G01N33, B01J4, B65D83, G01N35