IMAGING APPARATUSES AND METHODS

Abstract: An imaging apparatus, e.g. radiographic scanner (A) generates a high energy image representation which is stored in a high energy image matrix (V) and a low energy image representation which is stored in a low energy image memory (U). A pair of filter function selecting circuits (C) select a first material specific filter function (K) and second material specific filter function (K), respectively. The first material filter function selecting circuit (C) selects and adjusts the first material filter function (K) in accordance with the pixel value of the low energy image representation for each corresponding pair of pixel values. Convolvers (44, 46) convolve pixel values from the high and low energy image representations with the selected and adjusted filter functions (K). A first material transform function (48) transforms the filtered high and low energy image representations into a first or other material specific image representation (42). The other filter selecting and adjusting circuit (C) selects and adjusts the second material specific filter functions (K) which are convolved with the high and low energy image representations by convolvers (54, 56). A second material specific transform function (58) transforms the filtered high and low energy image representations into a second material basis image.

Description: This invention relates to imaging apparatuses and methods. The invention finds particular application in dual energy, digital radiography and will be described with particular reference thereto. However, it is to be appreciated that the invention may find further application in other imaging apparatus and methods such as computed tomography apparatus and methods and the like. In a conventional film radiography system, an x-ray source directed a divergent beam of x-rays through a patient. After passing through the patient the x-ray beam irradiated a phosphorescent screen as well as a light and x-ray sensitive film positioned adjacent the screen . As the radiation passed through the patient, it was attenuated in accordance with the tissue through which it passed to produce a shadow image on the film. The radiologist examined the gray scale, i.e. the light and dark regions, of the film directly for diagnostic purposes. In digital radiography, the gray scale of each pixel or incremental region of the image was represented by an electronic, digital value. These digital values were processed by various data processing and image enhancement techniques to improve the diagnostic value of the image. Various techniques have been developed for digitizing film and other shadowgraphic images to derive the electronic digital values. In one prior art digital radiographic technique, the digital values were derived directly from photographic film using a photodensiometer, video camera, or the like. In another prior art technique, a phosphor with a long term memory temporarily recorded the shadowgraphic image. A photo-sensitive apparatus converted the phosphor luminescence into corresponding digital values on a pixel by pixel basis. The intensity of x-ray beams traversing the patient have also been converted directly into electronic signals. An array of electronic radiation detectors was disposed opposite the patient to receive the x-rays passing therethrough. In one technique, often denoted as "scan or slit projection radiography", a thin fan beam of radiation passed through a narrow plane of the patient and impacted a linear array of x-ray detectors. The radiation fan and the detector array were moved transverse to the fan beam plane to scan a selected rectangular region of the patient. In another direct detection technique, an "area" beam of radiation was directed through the entire rectangular region of interest simultaneously to impact upon a large rectangular detector array. The intensities detected by the detectors were digitized for appropriate data processing and display on a video monitor or the like. The material or body tissue can be characterized by the difference in its attenuation of a high energy and a low energy x-ray beam. To improve the diagnostic value of radiographic images, images of the region of interest have been constructed from both high and low energy radiation. In KV switching, dual energy radiography, two time sequential images were taken, one with higher energy x-rays and the other with lower energy x-rays. In dual detector scanners, both images were taken simultaneously with back to back detectors, one of which was sensitive primarily to the lower energy x-rays and the other was sensitive primarily to the higher energy x-rays. In the prior art dual energy digital radiography, both high energy and low energy electronic image representations were derived. Each representation commonly included a rectangular array of pixels, each pixel having a pixel value indicative of the degree of radiation attenuation or transmissivity through a corresponding path of the region of interest. The pixel value variations were commonly represented by gray scale variations in man-readable images. Utilizing the transform functions set forth in "Generalized Image Combinations in Dual KVP Digital Radiography," L.A. Lehmann, et al., Medical Physics, Vol. 8, No. 5, pages 659-667, September/October 1981, the high and low energy specific images were transformed into one or more material specific basis image representations. The Lehmann, et al. transform operated on the pixels of the high and low energy images that correspond to the same volumetric subregion of the region of interest to produce a corresponding pixel value of the material specific image. Most commonly, two basis images were generated - one for water or soft tissue and the other for bone or calcium. For calibration purposes, plexiglass was utilized to approximate water and soft tissue and aluminum was utilized to approximate bone and calcium. Other transformations, such as pixel by pixel subtraction of weighted high and low energy images, have also been utilized. One of the problems with the Lehmann, et al. transformation was that it amplified the noise of the images, i.e. the basis images had a lower signal-to-noise ratio than either the high or the low energy images. The random noise degradation was particularly bad in the high x-ray attenuation or thick portions of the spine which were represented by relatively low pixel values. Various techniques have been developed for operating on the soft tissue and bone specific basis images to reduce the effect of random noise. One technique was to convolve each pixel of the basis image with a smoothing or filter function that averaged each pixel value with a percentage of the average value of the surrounding pixels. One drawback of this technique was that it removed the apparent random noise in the dense bone regions of the image by blurring the entire image. To avoid blurring all regions of the basis image, others have provided a region specific filter function. Random noise commonly appears as a speck of a different intensity from the surrounding areas, i.e. a pixel value that is much larger or smaller than the values of adjacent pixels. Specifically, the deviation between a pixel value and each of its surrounding neighbors was determined. If greater than a preselected deviation was observed, the blurring filter function was applied to that pixel of the basis image. If less than the preselected deviation was observed, no filtering was applied to that pixel. One disadvantage of this selective filtering technique is that the deviation between neighbouring pixel values was not always an indication of noise. Rather, the deviation may have been the result of a tissue or bone boundary, a thin blood vessel, or the like. This led to an averaging which tended to blur edges and obscure fine details of the filtered basis image. Other filtering and data processing techniques, such as edge enhancement techniques, other types of smoothing or filtering, and the like have also been performed on the resultant basis images. It is an object of the present invention to provide an imaging apparatus and method wherein the above disadvantages are overcome. According to a first aspect of the present invention there is provided an imaging apparatus comprising: a first image memory means for storing an electronic pixel value for each pixel of a first radiation energy level image representation; a second image memory means for storing an electronic pixel value for each pixel of a second radiation energy level image representation of the same region as said first image representation; means for producing a first irradiated material specific composite image from said pixel values of said first and second representations and filter means for reducing noise degradation in said image characterised in that said filter means operates on each pixel value of said first representation with a first material specific filter function and operates on each pixel value of said second representation with said first filter function and the apparatus includes a first transform means for transforming the filtered pixel values into said first composite image. According to a second aspect of the present invention there is provided a method of imaging comprising the steps of: generating first and second radiation energy level image representations of the same region of a subject; producing a first irradiated material specific composite image from said first and second representations and reducing noise degradation in said image by filtering characterised in that said reducing noise degradation comprises filtering the first image representation with a first material specific filter function to produce a first filter function filtered first image representation; filtering the second image representation with the first filter function to produce a first filter function filtered second image representation; and transforming the filtered first and second image representations with a first transform function into said first composite image. Two imaging apparatuses and methods in accordance with the invention will now be described, by way of example, with reference to the accompanying drawings in which:- Figure 1 is a schematic diagram of a first imaging apparatus; Figures 2A,2B, 3A and 3B illustrate a filter function alteration scheme for use in the two imaging apparatuses and methods; and Figure 4 is a schematic diagram of a second imaging apparatus. With reference to Figure 1, a diagnostic scanner A such as a digital, x-ray slit scanner, a CT scanner, a magnetic resonance imager, or the like generates a pair of image representations of the same region of interest of a subject i.e. a low energy image U and a high energy image V. An adjustable filter and transform means B converts the high and low energy images into one or more material specific or other composite images. A filter altering means C monitors at least one of the high and low energy images to determine the relative magnitude of the signal-to-noise ratio at each image pixel and alters the function applied in the filter and transform means B accordingly. The lower the signal-to-noise ratio is in a subregion, the more the pixel values representing the subregion are filtered or smoothed. The scanner A illustrated in Figure 1 for purposes of explanation is a slit scan projection type digital radiography system. It includes an x-ray source 10, such as an x-ray tube, which generates a polyenergetic fan beam 12 of x-rays having at least two energy levels. An entrance collimator 14 and an exit collimator 16 collimate the x-ray beam passing through the patient to a predefined fan shaped plane. A first or low energy detector array 18 includes a first linear array of detectors for detecting the low energy x-rays of the x-ray beam. A second or high energy x-ray detector array 20 includes a linear array of x-ray detectors disposed directly behind the low energy detector array to detect the high energy x-ray photons. The stopping power of the low energy detectors is such that primarily low energy photons are stopped and transformed to electrical signals, while most high energy photons pass therethrough. The high energy detectors are configured of a denser higher atomic number material with more stopping power to stop and convert the high energy photons into electrical signals indicative of the intensity of high energy radiation impinging thereon. One detector for each of the high and low energy arrays is disposed in alignment back to back with the x-ray source such that a corresponding pair of the detectors detect high and low energy radiation which has traversed the same line or subregion of the patient. An x-ray absorptive material 22, such as a sheet of copper, absorbs middle energy x-ray photons that have sufficient energy to pass through the low energy detectors. The thickness of the copper sheet is selected to absorb photons whose energy is below a preselected high energy level. In this manner, relatively distinct and separated high and low energy photon levels are detected. A mechanical drive 24 causes the high and low energy detector arrays and the entrance and exit collimators to be swept transverse to the plane of the beam such that a rectangular region of interest of the patient is irradiated. An encoder 26 changes the address for the low and high energy images U and V each time the detector array moves an incremental distance. In this manner, sweeping the detector array provides analogous data to a pair of rectangular high and low energy detector grids. Optionally, such detector grids may be provided with the elimination of the mechanical drive 24 and encoder 26 such that all pixels of the high and low energy images are collected simultaneously rather than column by column. Each detector of the high and low energy detector arrays produces an analog electronic output signal which varies in proportion with the intensity of x-rays which it receives. In the preferred embodiment, each detector includes a scintillation crystal which scintillates or emits light in proportion to the intensity of the received radiation. A photodiode produces an analog output signal whose amplitude varies in accordance with the intensity of the light from the scintillation crystal. Detectors which convert the radiation directly into electrical signals, CCD devices, and other known radiation detectors are also contemplated. Analog to digital converters 28 convert the analog intensity signals into digital representations of the radiation intensity. The high and low energy image representations are each defined by a rectangular array of pixels, corresponding to a rectangular array of subregions of the scanned region of interest The digital pixel values corresponding to each pixel of the images or subregions of the region of interest are stored in corresponding memory elements of low and high energy image memories U and V. In the illustrated embodiment, one pixel in each column of the images corresponds to a corresponding detector in the detector array. Each time the detector array is swept an incremental transverse distance, the data for the next adjacent pixel column is generated. Because the detector arrays are back to back, each pixel in the low energy image representation has a corresponding pixel in the high energy image representation that represents the same subregion of the region of interest. In the preferred embodiment, subregions of the subject which attenuate radiation the most, such as dense bone, cause the scintillation crystals to generate less light, hence produce smaller analog signals and lower digitial pixel values. Other numbering schemes fo the pixel values may, of course, be utilized. The values may vary linearly, logrithmically, or with other preselected relationships with x-ray intensity. The adjustable filter and transform means B includes a first material specific image filter and transform means 40 which filters and transforms the high and low energy images into a first or soft tissue specific image stored in memory 42. A first filter means convolves the low and high energy image representations separately pixel by pixel with an adaptive first filter function that varies from pixel to pixel to produce filtered low and high energy image representations. A first convolver 44 operates on the low energy image pixel values with the first filter function to produce the filtered low energy image representation. A second convolver 46 operates on each of the high energy image pixel values with the same first filter function as the corresponding low energy image pixel to generate the filtered high energy image representation. That is, the low energy image pixel value for the ith column and the jth row, U(i,j), and the high energy image pixel value for the same column and row, V(i,j), are each convolved with the same filter function k(i,j) to generate filtered values U′(i,j) and V′(i,j) corresponding to the (i,j)th pixel. Optionally, a filltered image memory means may be provided for storing the filtered high and low energy images from the convolvers 44 and 46. A first transform means 48 operates on the filtered low and high energy image representations U′ and V′ with the first transform F to generate a selected material specific image I. That is, the material specific image I is a function F of the filtered high and low energy images, U′ and V′: I = F(U′,V′) (1). Various functions F may be selected. As one example, each pixel value of the material specific image I may be the difference of the corresponding pixels of the high and low energy images: I(i,j) = V′(i,j) - U′(i,j) (2). As yet another example, the material specific image may be other linear combinations of the filtered high and low energy images, such as a weighted averaging: where m and n are weighting factors. In the preferred embodiment, a transform analogous to the transform set forth by Lehmann, et al. is utilized. Each pixel of the material selected image is related logrithmically to the corresponding pixels of the filtered high and low energy images: where k₁, k₂, k₃, k₄, and k₅ are constants which are determined for the given scanner A and for a selected material to which the image is to be selective in an initial calibration process. Due to the hardware constraints, the k constants will be different for each selected scanning apparatus. Moreover, different constants will be selected for a soft tissue selective image, a bone selective image, and other material selective images. Plexiglass may be utilized for an initial calibration to select the k constants for a soft tissue specific image and aluminum may be utilized as a calibration phantom to select the calibration constants k for a bone specific image. A second material specific filter and transform means 50 filters and transforms the high and low energy images into a second, preferably a bone specific image stored in memory 52. A pair of convolvers 54 and 56 operate pixel by pixel on corresponding pixels of the high and low energy image representations with a second adaptive filter function K₂. The convolvers 54 and 56 perform a similar convolution as convolvers 44 and 46 except with a different filter function that is uniquely selected for the material specific image to be generated. A second transform means 58 operates on the filtered high and low energy images with a second transform G to transform them into a second material selective image, preferably a bone selective image I. A display means 60 selectively displays the soft tissue and bone specific images from memories 42 and 52. As discussed above, the function G may be a difference, weighted average, logrithmic combination, or other linear or non-linear combination of the corresponding pixels of the filtered high and low energy image representations. Preferably, the second transform G implements Equation (4) except that the values of the constants k are selected specifically for bone or aluminum rather than soft tissue or plexiglass. Where appropriate, additional material specific filter/transform means may be provided for filtering and transforming the high and low energy images into images which are specific to other materials. Although the filter convolution and the transform are shown as separate operations, it is to be appreciated that some filter and transform functions may be combined into a single adaptive function to expedite data processing. The filter altering means C projects the signal-to-noise ratio at each pixel of the image in accordance with the level of the pixel value and alters the filter function or the transform according. The lower the pixel value, i.e. the greater the radiation attenuation, the greater the potential that the pixel value will include significant noise or be in a noisy region. As the pixel value increases, hence, the radiation attenuation decreases, the signal to noise level ratio improves and the amount of filtering is reduced. In the preferred embodiment, the filter function K is defined by a 3 x 3 kernal matrix: Convolving a given pixel value U(i,j) with this filter function, replaces the given pixel value with the sum of A times the given pixel value plus B times each of the eight immediately adjacent pixel values, i.e. the filtered image U′ is defined by: The values of A and B are selected in accordance with the magnitude of the given pixel value. The preferred embodiments of A and B for soft tissue are defined by the curve of FIGURES 2A and 2B. With specific reference to FIGURES 2A and 2B, when the pixel value is below a preselected minimum threshold 70, about 2% of the pixel value dynamic range in the preferred embodiment, the region is assumed to be very noisy. Accordingly, A and B are each selected to be 1/9. That is, the pixel value is replaced with the average of itself and its eight surrounding pixel values. When the pixel value is above a preselected high threshold 72, preferably about 20% of the pixel value dynamic range, the pixel value is unchanged. That is, A=1 and B=0. In between the high and low threshold values, the relative magnitudes of A and B vary linearly with the pixel levels. In the embodiment illustrated in FIGURES 2A and 2B, the value of A varies linearly between 1/9 and one; the value of B varies linearly between 1/9 and zero. With reference to FIGURES 3A and 3B, a different filter function is preferably selected for the soft tissue and bone specific images. Rather than the relationship illustrated in FIGURES 2A and 2B for soft tissue, the preferred values of A and B for a bone specific image are illustrated in FIGURES 3A and 3B. For low pixel values or high x-ray attenuation below a low threshold 74, each pixel is again averaged evenly with its surrounding neighbors. Above a preselected high threshold level 76, each pixel continues to be averaged with its surrounding neighbors. However, the value of A is selected at 1/2 and the value of B is selected at 1/16. Between the high and low threshold values, the value of A varies between 1/9 and 1/2 linearly and the value of B varies linearly between 1/9 and 1/16. Other relationships between A and B may be selected. However, it is preferred that: A + 8B = constant (7) In the illustrated embodiment, the constant is one. Other relationships between A and B may clearly be selected, for example, their values may change exponentially, logrithmically, or along other complex functions. For example, A and B may vary with a generally S-shaped curve in which A asymptotically approaches 1/9 at one extreme and 1 for soft tissue and 1/2 for bone at the other extreme; and B asymptotically approaches 1/9 at one extreme and zero for soft tissue and 1/16 for bone at the other extreme. This function may vary continuously over the full dynamic range of pixel levels without cut off thresholds. Other filter functions or kernals K may also be selected. For example, the kernal may be other sizes, such as a 5 x 5 matrix which averages each pixel value with some fraction of the eight immediately surrounding pixel values and the sixteen next most immediately surrounding pixel values. Moreover, as the kernal matrix becomes larger, the pixel values within each surrounding ring may vary generally in accordance with its radial distance from the center rather than solely as a function of the square ring. Other convolution and filter functions may optionally be selected. With reference again to FIGURE 1, the preferred noise level determining the filter altering means C includes separate circuitry for each of the material specific images. This allows a different filter function, such as the filter function of FIGURES 2 and 3, to be selected for each material specific image. However, because each of the filter altering means C is of the same construction, it is to be appreciated that the following discussion applies equally to both. Where appropriate, an address scaler means 80 may adjust the low energy pixel values U(i,j) to correspond to the addresses of a kernal or filter function selection means 82. Preferably, the low energy image representation is used to select the filter function for the corresponding pixels of both the low and high energy images. In a preferred embodiment, the filter function selection means includes a first look-up table 84 which is addressed by the first pixel value U(i,j) to look up the corresponding A value and a second look-up table 86 which is addressed by the pixel value to look up the corresponding B value. A kernal matrix means 88 assembles the kernal matrix or filter function K from the values retrieved from the look-up tables 84 and 86. If larger kernal matrixes are used, additional look-up tables may be provided for selecting the additional matrix values. Optionally, the filter function selection means 82 may be an arithmetic unit which calculates the A and B values mathematically from each pixel value U(i,j). With reference to FIGURE 4, the first and second or high and low energy images may be recorded at different times. An image digitizer 100 may convert a film, long term memory phosphor, or image intensifier output image into pixel values for corresponding pixels of a first or low energy image for storage in a first image memory means 102. Subsequently, a second film, phosphor, or image intensifier image taken through the same region of the patient may be digitized by the digitizer for storage in a second image memory 104. If the first and second film or phosphor images were taken with different energies of radiation, the first and second digital images will represent high and low energy images of the same region. Appropriate indexing to align the images may be required. In accordance with the level of pixel values in the low energy or first image, filter function selecting means C select the appropriate filter functions for convolvers 110, 112, 114, and 116 which generate filtered images for storage in filtered image memories 120, 122, 124, and 126. An adaptive transform means 130 combines the filtered images in accordance with the level of pixel values therein. A pixel value monitoring means 132 monitors the amplitude of pixel values of one of the images, preferably one of the filtered low energy images. Various transform functions may be selected. The image created by the transform means 130 is stored in a composite image memory 134. For example, the transform means 130 may sum corresponding pixel values of all four filtered images when the corresponding pixel value of the monitored image is in a preselected amplitude range, such as a central range. For low amplitude ranges, the corresponding pixels of the two filtered high energy images may be added. In between the central and low ranges, a weighted averaging may be performed. Analogously, in a high pixel amplitude range, the corresponding pixels of the low energy image might be added. Between the middle and high pixel value ranges, a ramp function or the like might be selected as a basis for performing a weighted averaging. Other combination equations are, of course, contemplated.

Claims: An imaging apparatus comprising: a first image memory means (102) for storing an electronic pixel value for each pixel of a first radiation energy level image representation (U); a second image memory means (104) for storing an electronic pixel value for each pixel of a second radiation energy level image representation (V) of the same region as said first image representation; means for producing a first irradiated material specific composite image from said pixel values of said first and second representations (U,V) and filter means for reducing noise degradation in said image characterised in that said filter means (44, 46, 110, 112) operates on each pixel value of said first representation (U) with a first material specific filter function (K) and operates on each pixel value of said second representation (V) with said first filter function (K) and the apparatus includes a first transform means (48, 130) for transforming the filtered pixel values into said first composite image. An apparatus according to Claim 1 further comprising a first filter function altering means (C) for selectively altering the first filter function (K) in accordance with a statistical probability that the pixel to be filtered is free from noise degradation. An apparatus according to Claim 2 wherein the filter function altering means (C) includes at least one look-up table (84,86) which is operatively connected with at least one of the first and second image memory means to be addressed by the pixel value of at least one of each corresponding pair of pixels to be filtered, the look-up table (84,86) retrieving kernal matrix values (A,B) of a filter function (K) in accordance with the addressing pixel value and wherein the first filter means (44,46,110,112) includes a convolving means (44,46) for convolving the first and second image memory means pixel values with the kernal matrix (K). An apparatus according to Claim 1 further comprising: a second filter means (54,56) for operating on each pixel value of the first image representation (U) from the first memory means with a second material specific filter function (K₂) and for operating on each pixel value of the second image representation (V) from the second memory means with said second filter function (K₂); a second transform means (58) for transforming filtered pixel values from the first and second memory means into a second irradiated material specific composite image; and a second composite image memory means (52) for storing the second composite image. An apparatus according to Claim 4 further comprising a filter function altering means (C,C) for selectively altering the first and second filter functions (K,K₂), the filter function altering means (C,C) being operatively connected with one of the first and second image memory means for altering the first and second filter functions (K,K₂) in accordance with each pixel value to be filtered by the first and second filter means (44,46,54,56). An imaging apparatus as claimed in Claim 5 further comprising: a radiation source (10) for producing at least higher energy and lower energy radiation; a radiation detection means (18,20) for separately detecting the higher and lower energy radiation traversing a selected region of interest of a subject and for producing digital electronic pixel values indicative of the intensity of higher and lower energy radiation received thereby; wherein said second image memory means is operatively connected with the detector means (20) for storing the higher energy radiation intensity indicative digital electronic pixel values for each pixel for a higher energy image representation (V) of the region of interest; and said first image memory means is operatively connected with the detector means (18) for storing the lower energy radiation intensity indicative digital electronic pixel values for each pixel for a lower energy image representation (U) of the region of interest. A method of imaging comprising the steps of: generating first and second radiation energy level image representations (U,V) of the same region of a subject, producing a first irradiated material specific composite image from said first and second representations (U,V) and reducing noise degradation in said image by filtering characterised in that said reducing noise degradation comprises filtering the first image representation with a first material specific filter function (K) to produce a first filter function filtered first image representation (U'); filtering the second image representation with the first filter function (K) to produce a first filter function filtered second image representation (V'); and transforming the filtered first and second image representations with a first transform function (F) into said first composite image (I). A method according to Claim 7 further comprising the steps of: filtering the first and second image representations (U,V) with a second material specific filter function (K₂) to produce second filter function filtered first and second image representations (U",V"); and transforming the second filter function filtered first and second image representations with a second transform function (G) into a second irradiated material specific composite image. A method according to Claim 8 wherein: the first and second image representations (U,V) represent high and low energy specific radiograph images respectively; and the first and second transform functions (F,G) transform the filtered image representations (U',V',U",V") into images (I) representative of a first material and a second material such that the first composite image is a first material specific image and the second composite image is a second material specific image. A method according to Claim 7 or Claim 8 or Claim 9 wherein: the first and second image representations (U,V) are each defined by a plurality of pixels, each pixel of the first image representation having a corresponding pixel in the second image representation which represents the same subregion of an imaged region of interest, each image representation having a plurality of pixel values, each pixel value corresponding to one of the pixels, and said method further comprises the step of altering the first filter function (K) in accordance with a characteristic of each pixel value to be filtered such that the first filter function (K) is varied in accordance with the pixel value of each pixel to be filtered. A method according to Claim 8 or 9 further comprising the step of selecting at least one of the first filter, second filter, first transform and second transform functions (K, K₂, F, G) in accordance with characteristics of at least one of the first and second image representations (U,V). A method according to Claim 11 wherein: each filter function (K,K₂) includes a matrix; the filter function selecting step includes selecting the values (A,B) of matrix elements; and the filtering step includes convolving pixel values of the image representation (U,V) with the matrix. A method according to Claim 11 or 12 wherein: the image representation generating step includes irradiating the subject with radiation of a first energy level to generate the first image representation (U) and irradiating the subject with radiation of a second energy level to generate the second image representation (V); and the transform functions (F,G) are selected such that the first composite image is material specific to a first material and the second composite image is material specific to a second material.

Inventors: LAURO, KAREN L., SONES, RICHARD A.
Applicants: PICKER INTERNATIONAL, INC.
Application year: 1987
Main classification: G06F15
IPC codes: A61B6, G06T5, G06T1, G01N23, H04N7