TECHNIQUE FOR OBTAINING INFORMATION ASSOCIATED WITH AN INDIVIDUAL'S BLOOD PRESSURE INCLUDING SPECIFICALLY A STAT MODE TECHNIQUE

Abstract: Techniques for determining different parameters asso­ ciated with an individual's blood pressure in a non-invasive manner are disclosed herein. These techniques include (a) generating a blood pressure waveform (15) corresponding to the individual's actual waveform, whereby the mean pressure of the individual can be readily calculated, (b) generating a transformation curve (12) unique to the patient from his dia­ stolic and systolic pressures and his cuff pulses, (c) succes­ sively monitoring certain parameters of the patient's blood pressure including his systolic and diastolic pressures over closely spaced intervals of time without having to subject the patient to cuff pressures much greater than his diastolic pres­ sure, other than initially or not at all utilizing what is referred to as a stat mode, and (d) measuring a patient's diastolic and sys­ tolic blood pressures at any given instance without ever having to subject the patient to cuff pressures P c much greater than his diastolic pressure.

Description: TECHNIQUE FOR OBTAINING INFORMATION ASSOCIATED WITH AN INDIVIDUAL'S BLOOD PRESSURE INCLUDING SPECIFICALLY A STAT MODE TECHNIQUE The present invention relates generally to blood pressure evaluation procedures and more particularly to non-invasive techniques for determining certain information associated with blood pressure. The most reliable ways presently known for obtaining information relating to an individual's blood pressure require invasive procedures. Such procedures are not carried out routinely but only under extreme circumstances, for example during heart surgery. Under less critical conditions, blood pressure information including specifically an individual's systolic (maximum) and diastolic (minimum) blood pressures is obtained non-invasively. There are two well known non-invasive techniques presently being used today, one is commonly referred to as auscultation and the other is based on oscillometry. Both of these non-invasive techniques use the standard arm cuff which most people are familiar with. However, in the auscultatory method, the systolic and diastolic pressures are determined by listening to certain sounds (Korotkoff sounds) which occur as a result of the cuff first being pressurized and then depressurized whereas oscillometry actually measures changes in pressure in the cuff as a result of changes in blood pressure as the cuff is first pressurized and then depressurized. As will be seen hereinafter, the various embodiments of the present invention are based on oscillometry. In order to more fully appreciate these embodiments, reference is made to applicant's own United States Patent 3,903,872 (the Link patent) for obtaining blood pressure information non-invasively. This patent which is incorporated herein by reference describes, among other things, a way of obtaining the diastolic pressure of an individual in accordance with a technique which will be discussed in more detail hereinafter. In United States Patents 4,009,709 and 4,074,711 (Link et al) which are also incorporated herein by reference, non-invasive techniques using oscillometry are disclosed for obtaining the systolic pressure of an individual. These techniques will also be discussed hereinafter. While the various procedures described in the Link and Link et al patents just recited and other patents held by applicant are satisfactory for their intended purposes, it is an object of the present invention to provide additional uncomplicated and yet reliable techniques for obtaining different types of information relating to an individual's blood pressure. A more specific object of the present invention is to provide a different uncomplicated and yet reliable technique for generating non-invasively a waveform closely approximating an individual's true blood pressure waveform which, heretofore, has been obtainable by invasive means only. Another particular object of the present invention is to provide a new way for measuring and calculating the mean arterial pressure of an individual. Another specific object of the present invention is to provide a new, uncomplicated and yet reliable technique for generating a transformation curve unique to a given patient. Still another specific object of the present invention is to provide a technique for successively monitoring certain parameters of a patient's blood pressure including his systolic and diastolic pressures over closely spaced intervals of time without having to subject the patient to cuff pressures much greater than his diastolic pressure, other than initially (for purposes of calibration). Yet another specific object of the present invention is to provide a technique for measuring a patient's diastolic and systolic blood pressures at any given instance without ever having to subject the patient to cuff pressures much greater than his diastolic pressure. As will be described in more detail hereinafter, the objects just recited are achieved by means of oscillometry. In accordance with this technique, a suitably sized cuff, for example one which is 20 inches long and 5 inches wide, is positioned around the upper arm of an individual, a human being specifically or a mammal in general (hereinafter referred to as the patient) and initially pressurized to a certain minimum level. As will be seen hereinafter in accordance with one aspect of the present invention, this minimum level need not be much greater than the patient's diastolic pressure to obtain certain information about the patient's blood pressure including his diastolic and systolic pressures. However, heretofore, in order to measure these pressure values and obtain other information, it was necessary to subject the patient to a minimum cuff pressure greater than the patient's systolic pressure, for example 180 Torr. It is assumed that this latter cuff pressure will cause the patient's artery within the sleeve to completely collapse. Thereafter, the cuff pressure is gradually reduced toward zero during which time the cuff continuously changes in pressure in an oscillating fashion due to the combination of (1) the internal blood pressure changes in the patient's artery and (2) changes in cuff pressure. The latter at any given time in the procedure is known and oscillatory changes in cuff pressure can be readily measured, for example with an oscilloscope. By using these two parameters in conjunction with information which may be made available from methods disclosed in the above-recited United States patents and the techniques of the present invention to be described hereinafter, it is possible to achieve the foregoing objectives in uncomplicated and reliable ways. It should be noted at the outset that the typical 5" wide pressure cuff entirely surrounds a corresponding 5" length of artery. The tissue of the arm is for the most part incompressible, and therefore any change in the volume of the artery, caused for example by pulsations of blood, results in a corresponding change in the volume of air in the air bladder which is within the cuff and therefore adjacent to the arm. This change in air volume produces a small but accurately measurable pressure change in the air. This equivalence of pressure pulsations in the cuff bladder to volume pulsations of the artery is the essence of oscillometry. In order to more fully appreciate the various techniques of the present invention, the following more detailed background information is provided in conjunction with Figures 1-5 of the drawings where: FIGURE 1 (corresponding to Figure 6 in United States Patent 3,903,872) diagrammatically illustrates the shapes of successive cuff pressure versus time pulses (cuff pulses) as the measured cuff pressure changes from 90 Torr to 80 Torr to 70 Torr, assuming the patient has a diastolic pressure of 80 Torr. FIGURE 1A diagrammatically illustrates a full series of cuff pulses corresponding to those in Figure 1 from a cuff pressure of 160 Torr to a cuff pressure of zero. FIGURE 2 diagrammatically illustrates what may be best referred to as a "transformation" curve or a volume/pressure (V/P) curve corresponding to the patient's arterial volume (V), that is, the volume of the patient's artery within the cuff (as measured by cuff volume) versus wall pressure fPw) across the artery wall within the cuff and, superimposed on this curve, a curve which is intended to correspond to the actual blood pressure waveform of a patient, the two curves being provided together in order to illustrate the principles of oscillometry, as relied upon in the above-recited patents. As will be described below, arterial volume changes tV produce cuff pulses P (ac) and so Figure 2 also represents a curve which "transforms" blood pressure pulses or wall pressure pulses into cuff pulses. FIGURES 3 and 4 diagrammatically illustrate the transformation curve of Figure 2 in ways which display techniques for obtaining a given patient's systolic and diastolic blood pressures in accordance with the Link and Link et al patents recited above. FIGURE 5 diagrammatically illustrates a curve corresponding to the compliance of the patient's artery, that is, a curve which displays the ratio AV/PW against the arterial wall pressure Pw, where AV is the incremental change in the arterial volume corresponding to a preselected change in wall pressure APW for different cuff pressures, this latter curve being initially determined in order to provide the transformation curve (V/P curve) of Figure 2 by means of integration, as will be seen. Because arterial volume changes produce cuff pulses, Figure 5 also represents the relationship #Pc (ac)/APw. Turning first to Figure 1, this figure diagrammatically illustrates three successive cuff pressure waveforms lOh, 10i and 10j which correspond to the change in arterial volume in a pressurized cuff, as described above, at three different cuff pressures, specifically cuff pressures of 90 Torr, 80 Torr and 70 Torr respectively. In actual practice, a greater number of cuff pressure waveforms (hereinafter referred to as cuff pulses) are generated starting at a high cuff pressure such as 160 Torr and ending at a cuff pressure of zero, as will be seen in Figure 1A. By generating these waveforms at known cuff pressures, both the diastolic and systolic pressures of a patient can be determined in accordance with the above-recited patents. While this will be explained in more detail below, it is important to note initially that each waveform has what may be referred to as a systolic rise Sr at one end of the waveform, a diastolic decline Dd at the opposite end and a maximum amplitude A. Moreover, for purposes of graphical illustration, because each applied cuff pressure to which the patient is subjected is a fixed value or at least a slowly changing value, it will sometimes be referred to hereinafter as Pc (dc). At the same time, because the cuff pulses themselves are the result of a fluctuation in cuff pressure with time (due to the change in the patient's blood pressure), they will sometimes be referred to herein as Pc (ac). Note also that Pc (dc) may assume values from 0 to 250 Torr whereas the cuff pulses Pc (ac) usually have peak to peak values less than 10 Torr. The systolic rise Sr, the diastolic decline Dd and the amplitude A vary from pulse to pulse for reasons to be explained hereinafter. It is because of these variations that the techniques disclosed in the Link and Link et al patents recited above can be used to determine the diastolic and systolic pressures. Specifically, as will be seen, when the diastolic pressure of a patient is equal to the applied cuff pressure Pc (dc), the cuff pulse Pc (ac) generated has a final diastolic decline which is greater in slope than the diastolic decline of any of the other cuff pulses. Thus, assuming that the final diastolic decline has a maximum slope at the cuff pulse 10i illustrated in Figure 1, the patient providing these waveforms would have a diastolic pressure of 80 Torr. At the same time, this patient's systolic pressure can be determined by first finding which of the cuff pulses displays a maximum amplitude A and then, moving up in cuff pressure, finding the cuff pulse having half that amplitude. The cuff pressure responsible for producing this half-amplitude pulse will approximately equal the patients systolic blood pressure. In order to more fully understand these capabilities, reference is made to Figures 2-5 in conjunction with the above-recited Link and Link et al patents. Turning now to Figure 2, attention is directed to the curves illustrated there in order to explain why the cuff pulses of Figure 1 result from changes in cuff pressure. The generally S-shaped transformation curve 12 illustrated is shown within a horizontal/vertical coordinate system where the horizontal axis is the transmural pressure or the wall pressure Pw across the artery wall of a given patient, within the confines of the applied cuff. The vertical axis corresponds to the arterial volume V of the artery within the cuff, as measured by the internal volume of the cuff itself. In actuality, the transformation curve transforms applied blood pressure waveforms (which directly effect Pw on the horizontal axis) to cuff pulses Pc (ac) (which are dependent on arterial volume V within the cuff on the vertical axis). It will be appreciated that since the cuff pulses Pc (ac) are caused by and are proportional to arterial volume changes EV, the vertical axis of the S-shaped curve of Figure 2 may be labelled by V or Pc (ac) interchangeably depending on the phenomena being described. The proportionality of Pc (ac) to V is valid over the central regions of the S-shaped curve of Figure 2 but may be less valid for very small cuff pressures Pc (dc). In order to fully understand this transformation curve (hereinafter also referred to as an arterial or a cuff curve), it is important to keep in mind the definition of Pw The wall pressure Pw of the artery of the patient at any given time is equal to the blood pressure Pb of the patient within the artery at that time less the applied pressure of the cuff Pc (dc). Thus: Pw = Pb - Pc (dc) .. (1) For purposes of the present discussion, it will be assumed that pressure is measured in Torr (mmHg) and that the section of the horizontal axis to the right of the vertical axis represents positive wall pressures while the section of the axis to the left of the vertical axis represents negative wall pressures. As a result, when no pressure is applied to the cuff (e.g. Pc=0), Pw at any given point in time is equal to the blood pressure of the patient at that time. As the cuff is pressurized, Pw decreases (moves to the left along the horizontal axis). When the cuff pressure Pc is equal to the blood pressure Pb at any given point in time, Pw at that moment is equal to zero (e.g. at the vertical axis). As the cuff pressure is increased beyond the blood pressure at any point in time, Pw at that time becomes more negative (moves further to the left on the horizontal axis). With the definitions of the vertical axis Pc (ac) or V and the horizontal axis Pw in mind, attention is now directed to an interpretation of the generally S-shaped cuff curve 12 within this coordinate system. For the moment, it is being assumed that this curve is characteristic of the particular patient being evaluated. That is, it is being assumed that the patient's artery within the cuff and therefore the cuff itself will change in volume along the S-shaped curve and only along the curve with changes in Pw Hereinafter, with regard to Figure 3, it will be shown that the transformation curve 12 of a given patient can be generated from his cuff pulses 10 and corresponding applied cuff pressures P (dc). Thus, for the time being, it will be assumed c that the transformation curve illustrated in Figure 2 corresponds to that of the given patient. With the foregoing in mind, the transformation curve of Figure 2 will now be examined. Let it first be assumed that no pressure is applied to the patient's cuff so that Pc (dc) equals zero. As a result, Pw equals the blood pressure Pb of the patient. In this regard, it is important to note that Pb varies with time between the patient's diastolic blood pressure Pb (D) and his systolic blood pressure P #b#5## For purposes of this discussion, let it be assumed that these values are known and that specifically the patient's diastolic blood pressure is 80 Torr and his systolic blood pressure is 120 Torr. Thus, with no pressure in the cuff, Pw (the wall pressure or transmural pressure) oscillates back and forth with time between Pb(D) and Pb(S), that is, between 80 Torr and 120 Torr. This 40 Torr measuring band is illustrated by dotted lines in Figure 2 at 14 and actually represents the patient's pulse pressure which is equal to 40 Torr in this case; pulse pressure e Pb(S) - Pb(D) = 120 - 80 = 40 Torr. The patient's actual blood pressure waveform 15 is superimposed on the V/Pw coordinate system in Figure 2 within the pulse pressure band 14. As seen there, this waveform is made up of a series of actual blood pressure pulses 16 (pressure versus time), each of which corresponds to a single beat of the patient's heart. Note that each pulse starts at a minimum pressure (the diastolic pressure of the patient) at a given time to and sharply increases along its leading edge which is the systolic rise 5r until it reaches a maximum (the patient's systolic blood pressure), at which time it drops back down along a trailing edge which includes a dichrotic notch and a diastolic decline Dd to the minimum pressure again at a second time to. At those points in time when the patient's blood pressure is at a minimum (that is, at the diastolic ends of pulses 16), the volume of the patient's artery and therefore the volume of the cuff is fixed by the arterial curve at the value indicated at V1(Pw=80). This corresponds to the minimum pressure level for the patient's cuff pulse Pc (ac) at an applied cuff pressure Pc (dc) of zero. On the other hand, whenever the patient's blood pressure is maximum (at the systolic end of each blood pressure pulse 16), the arterial curve fixes arterial and therefore cuff volume at the slightly higher value indicated at V2(PW=120). This correspond to the maximum pressure level for the patient's cuff pulse Pc (ac) at an applied cuff pressure Pc (dc) of zero. Therefore, it should be apparent that for each heart beat (e.g., the time increment from to to to), assuming a cuff pressure Pc (dc) of zero, the volume V (the cuff volume) moves between the values V1 and V2, thereby generating a cuff pulse 10q for each heart beat corresponding to those illustrated in Figure 1 but at a cuff pressure Pc (dc) = 0, as shown in Figure 1A. Thus, as the patient's blood pressure rises from a minimum to a maximum, the volume of the artery rises from V1 to V2 in a generally corresponding manner (and so does the cuff pulse 10q) and as the patient's blood pressure drops back down to a minimum, the arterial volume falls from V2 to V1 in a generally corresponding manner (and so does the cuff pulse 10q). Thus, each of the cuff pulses 10 in Figure 2 has a systolic rise Sr and a diastolic decline Dd corresponding to the systolic rise and diastolic decline of each blood pressure pulse 16. Having shown how the cuff pulses 10q are dependent upon the transformation curve at an applied cuff pressure of zero, we will now describe how the transformation curve causes these cuff pulses to change with applied cuff pressure. Let us assume now an applied cuff pressure P (dc) of 50 Torr. Under these conditions, P oscil c w lates back and forth between 30 Torr and 70 Torr. The 30 Torr value is determined by subtracting the cuff pressure Pc (dc) of 50 Torr from the diastolic blood pressure Pb(D) of 80 Torr and the 70 Torr value is determined by subtracting the same Pc (dc) of 50 Torr from the systolic blood pressure Pb(D) of 120 Torr. Thus, the entire 40 Torr band has merely been shifted to the left an amount equal to 50 Torr as indicated by the band 14'. Under these circumstances, Pw oscillates back and forth along a steeper segment of the arterial or transformation curve so as to cause the volume of the patient's artery and therefore the volume of the cuff to oscillate between the values V3 and V4. This results in the production of cuff pulses 10L at a Pc (dc) of 50 Torr. Note that the amplitude of each cuff pulse 10L is greater than the amplitude of each cuff pulse 10q. This is because the 40 Torr band 14' at an applied cuff pressure of 50 Torr is on a steeper part of the volume curve than the band 14 at an applied cuff pressure of zero. Indeed, as we increase the cuff pressure Pc (dc) (which decreases Pw) and therefore move the pressure band to the left on the horizontal axis, we first continue to move along steeper sections of the arterial curve and thereafter less steep sections. Therefore, the amplitude (see Figures 1 and 1A) of the corresponding cuff pulses 10q, 10L and so on will first increase to a maximum and then decrease again. At a cuff pressure Pc (dc) of 100 Torr, the entire 40 Torr pressure band is shifted to the left so as to uniformly straddle opposite sides of the vertical zero axis, as indicated at 14". This results in a corresponding cuff pulse 10g having approximately a maximum amplitude (AVmax in Figure 2). Moving still further to the left, at for example, an applied cuff pressure Pc (dc) of 160 Torr, the entire 40 Torr band is moved a substantial distance to the left of the vertical axis, as indicated at 14 " ' such that the resultant change in volume (amplitude of the corresponding cuff pulse 10a) is quite small. By increasing the cuff pressure to even a greater amount, the band is moved still further to the left, eventually producing very small changes in volume V. From a physical standpoint, this represents a collapsed artery. In other words, sufficient cuff pressure Pc (dc) is being applied over and above the internal blood pressure Pb to cause the wall of the artery to collapse. At the other extreme, that is, when the cuff pressure Pc (dc) is zero, there are no external constraints placed on the artery and the latter is free to fluctuate back and forth based on its internal pressure Pb only. Between these extremes, the amplitude of cuff pulse 10 (e.g. LIV) will increase to a maximum and then decrease again, as stated. It is this latter characteristic which is used to determine the patient's systolic pressure in accordance with the previously recited Link et al patents, as will be described with regard to Figures 3 and 4. As previously mentioned, it should be noted that a blood pressure increase causes an arterial volume increase. This arterial volume increase causes a cuff bladder air volume decrease which in turn causes a cuff bladder air-pressure increase. Therefore, at a given applied cuff pressure P (dc), a blood pressure increase results c in a cuff air pressure increase. This is emphasized as follows: blood + arterial B cuff air + cuff air pressure volume volume pressure increase increase decrease increase Thus: blood + cuff air pressure pressure increase increase or APb + #Pc (ac) The converse to the above is also true, that is, a decrease in blood pressure results in a decrease in cuff air pressure. Therefore, at a given applied cuff pressure Pc (dc), the amplitude Pc (ac) or Pac of a Patient's cuff pulse varies directly with the patient's blood pressure pulse. Referring to Figure 3, the same transformation curve 12 illustrated in Figure 2 is again shown but with a single superimposed pressure band 14'''' at a cuff pressure Pc of 120 Torr. Assume again that the diastolic pressure of the patient is 80 Torr and his systolic pressure is 120 which means that Pc (dc) is equal to the patient's systolic pressure for band 14"". Under these circumstances, Pw oscillates back and forth within band 14'''' between wall pressures of -40 Torr and zero, as shown. This results in a change in arterial volume aV (e.g., the amplitude A of a corresponding cuff pulse) which is approximately equal to one-half of the maximum change in arterial volume (e.g., max cuff pulse amplitude). It may be recalled that a maximum change in volume AV max (and therefore a maximum cuff pulse amplitude Amax) results from an applied cuff pressure Pc (dc) of about 100 Torr (e.g. the pressure band 14" in Figure 2). Thus, when the cuff pressure Pc is equal to the pa tient's systolic blood pressure P Pb(S), the amplitude A of the resultant cuff pulse 10 is about one-half of the amplitude of the cuff pulse having a maximum amplitude. Therefore, a patient's systolic blood pressure can be determined by first generating a series of cuff pulses across the cuff pressure spectrum, as in Figure 1A. From these pulses, the one having maximum amplitude Amax is determined and then the cuff pulse having half that amplitude (at a greater cuff pressure) is found. The cuff pressure Pc (dc) used to generate that pulse corresponds to the patient's systolic pressure. In other words, by evaluating the amplitudes of the various cuff pulses, the one corresponding to the band 14'' " illustrated in Figure 3 can be found. Once that pulse is found, its associated cuff pressure is assumed to be equal to the patient's systolic pressure. This is discussed in more detail in Link et al United States Patents 4,009,709 and 4,074,711 and means are provided in these latter patents for electronically making these evaluations. Returning to Figure 2, it should be noted that the actual blood pressure waveform 15 is shown having a uniform repetition rate, for example 60 pulses/minute, and that each blood pressure pulse 16 making up this waveform is identical to the next one. Both of these aspects of the waveform are assumed for purposes herein. Moreover, each pulse has its own systolic rise Sr and diastolic decline Dd, as mentioned heretofore. It should also be noted that the transformation curve 12 dictates the relationship between V or Pc (ac) (on the vertical axis) and Pw or Pc (dc) (on the horizontal axis) at each and every point on the individual blood pressure pulse 16, not merely at the extreme diastolic and systolic end points of each pulse. At the same time it should be kept in mind that this means that the transformation curve dictates the relationship between the amplitude Pc (ac) at any point on the blood pressure pulse 16 for any given applied cuff pressure Pc (dc). Thus, one could measure the change in volume AV or the change between two different points in time along the diastolic decline of the blood pressure pulse for different cuff pressures Pc (dc). In this case, the measuring band (e.g. the pressure difference between the two measuring points) is substantially narrower than band 14. As best illustrated in Figure 4, At1, is determined for a cuff pressure Pc (dc) of zero using the pressure band 18 which encompasses a small part of the diastolic decline of each blood pressure pulse 16. AV2, is determined for a cuff pressure of Pc (dc) of 50 Torr by shifting the band to 18' and, AV3' is determined for a cuff pressure P (dc) of 80 Torr (e.g. the patient's diastolic blood pressure) by shifting the band to 18". Finally AV4 ' is determined at an even higher cuff pressure by shifts to band 18''., Note that av is maximum when the applied cuff pressure #c (dc) is equal to the patient's diastolic blood pressure. Therefore, by determining the relative change in volume AV at the end of the diastolic slope of the patient's actual blood pressure waveform for each and every applied cuff pressure, the one cuff pressure producing a maximum volume change will correspond to the patient's diastolic blood pressure. The lowest pressure part of the diastolic decline Dd forming part of each pulse 16 is particularly suitable for this purpose since it can be readily located during each cycle of the waveform. This is because it immediately precedes the systolic rise 5r which is readily distinguishable each time it appears. This procedure is described in more detail in the previously recited Link Patent 3,903,872 along with means for carrying out this procedure electronically. Specifically, Figure 5 in this patent illustrates the first time derivative of the measured cuff pressure pulse (hereinafter p) at a time t within a patient's actual blood pressure pulse as a function of applied cuff pressure Pc (dc). In the illustration just provided the first derivative corresponds to AV and the time t corresponds to the temporal center of band 18, 18' and so on where t is on the diastolic decline of the blood pressure pulse close to the start of the next systolic rise. For purposes of convenience, the first time derivative of the measured cuff pressure and AV will be used herein interchangably. However, it is to be understood that, in actuality, AV reflects actual changes in arterial volume whereas the first time derivative is a result of actual changes in cuff pressure (which correspond directly to AV). This later point is further explained as follows. A straight forward variable to measure in the cuff pulse waveform is the slope of the pulse near the end of the diastolic decline; thus APc(ac)/At or p near the end of P pulse or just prior to the next systolic blood pressure rise. This increment of time At is an easily fixed increment of time which corresponds to a change in the blood pressure APb i.e., APb = Constant x At where At and therefore APb are arbitrarily but conveniently chosen for best results. It art follows that APc (ac)/At = constant x APc(ac)/APb, but the later differential relationship is the slope of the S-shaped curve of Figures 2, 3 and 4. We then have, P = APc(ac)/At = constant x APc (ac)/AP# = constant x constant x AV/APb or p - AV/APb, and finally p - AV for a constant APb. In all of this, APb = A Pw by the definition Pw = Pb - Pc (dc) where Pc (dc) is constant or slowly changing. The foregoing discussions for obtaining a given patient's systolic and diastolic blood pressures have assumed that the patient's transformation curve was known and corresponded to the one illustrated in Figures 2, 3 and 4. It is however possible to determine the patient's own transformation curve, if not already known, using the principles associated with Figure 4. Specifically, using the narrower bands 18, 18' and so on as measuring bands, the change in volume AV (e.g., the change in cuff volume) or p resultingfrom P resulting from different applied cuff pressures Pc (dc) is plotted, as shown in Figure 5. Thus at an applied cuff pressure Pc (dc) of zero, there is a relatively small change in volume AV or a small p, as evidenced by the small AV1, in Figure 4. As the cuff pressure Pc (dc) increases, the change in volume AV or p continues to increase to a maximum (@V3' in Figure 4) and then decreases. In mathematical terms, this curve represents incremental changes in volume divided by incremental changes in pressure or AV/AP (Figure 5) or actually changes in pas P = P - P (dc) P w b c changes. By integrating this p versus P curve we P w obtain the transformation curve or the V/Pw curve of Figures 2-4. Having discussed Figures 1-5 in regards to the prior art techniques for obtaining diastolic and systolic blood pressures and for generating a p versus Pw curve and a transformation curve for a given patient in accordance with the techniques described above and in the above-recited Link and Link et al patents, attention is now directed to the various aspects of the present invention in conjunction with Figures 6-9 where: FIGURE 6 diagrammatically illustrates an actual blood pressure pulse for a given patient. FIGURE 7 diagrammatically illustrates a plotted waveform which approximates the actual blood pressure pulse of Figure 6 and which is generated non-invasively in accordance with the present invention. FIGURE 8 diagrammatically illustrates a transformation curve similar to the one illustrated in Figures 2-4 but exaggerated along the vertical slope with enlarged portions of the diastolic decline forming part of an actual blood pressure waveform superimposed thereon. FIGURES 9 (a)-(d) diagrammatically illustrate four blood pressure waveforms having different blood pressure constants K. FIGURE 10 is a functional illustration of an arrangement for providing a curve which closely approximates a patients actual blood pressure waveform and also provides the patients mean pressure and blood pressure constant. Turning first to Figures 6-8, attention is now directed to a technique provided in accordance with the present invention for generating a waveform which closely approximates an individual patient's actual blood pressure waveform (for example, the blood pressure pulse 16 in Figure 2) without using an invasive device. For purposes of illustration, the assumed actual blood pressure pulse is shown graphically in Figure 6 at 20 where the patient's blood pressure (the vertical axis) is measured against time (the horizontal axis). From previous discussions and a knowledge of the subject matter of Link Patent 3,903,872 and Link et al Patents 4,009,709 and 4,074,711, the individual patient's diastolic and systolic pressures Pb(D) and Pb(S) can be first determined, thereby providing the minimum and maximum vertical points on the pulse as seen in Figure 6. At the same time, since the systolic rise (leading edge) of the actual pulse is readily detectable, the pulse's beginning and end points time wise (to and to') are also readily detectable. Therefore, using the same coordinate system in Figure 7 we will now describe a method for non-invasively determining the important features of the blood pressure pulse shown in Figure 6 and thus providing a useful approximation of the whole pulse. As appears in Figure 6, the horizontal (time) axis can be made to represent the patient's diastolic blood pressure with to being provided at the vertical axis, indicating the beginning of the waveform and to' a second point indicating the end of that waveform and the beginning of the next one. A dotted horizontal line L1 can then be drawn above the time axis at the patient's systolic blood pressure. A single point on this horizontal line can then be established as tOn This corresponds to the time, which is readily apparent from the measured cuff pressure pulses, at which the peak systolic pres sure Pb(S) #b#5# is reached. See for example the cuff pulses of Figure 1. The peak amplitude of each of these pulses corresponds to Pb (S) at time toW in the frame of reference just established. Having graphically provided the time and pressure axes t and P, the points to and to' and the dotted horizontal line L1 at the patient's systolic blood pressure, and the point tow on the horizontal line, attention is now directed to the way in which the waveform is completed in a non-invasive manner. To this end, reference is directed to Figure 8 which is similar to Figure 4, with one exception. It may be recalled from the previous discussion of Figure 4 in conjunction with Link Patent 3,903,872, a patient's diastolic blood pressure can be determined electronically by varying the applied cuff pressure Pc (dc) and detecting the resultant change in cuff volume AV or p (the first time derivative of the measured cuff pressure pulses) within the same pressure or measuring band (e.g., the band 18, 18' and so on in Figure 4) in the patient's actual blood pressure waveform, that is, along the diastolic decline just before the systolic rise. The cuff pressure Pc (dc) resulting in a maximum change in arterial volume QVmax or in a maximum p corresponds to the patient's diastolic blood pressure. The physical components for carrying out this process are described in the '872 patent and reference is made thereto. These components include means serving as a generator for detecting the beginning of the patient's systolic rise and measuring back therefrom, for example 50 milliseconds, in order to provide repeatedly a 50 millisecond measuring band. During that time the change in cuff volume AV or p is P measured by cooperating means for each applied cuff pressure Pc (dc). Means are also provided for determin ing when tV or p is at a maximum and for reading out the P cuff pressure Pc (dc) at EVmax or p max, this latter cuff pressure corresponding to the patient's diastolic pressure. In accordance with the present invention and as described generally in the '872 patent, the generator just recited can be used to provide a series of identical measuring bands of width Et moving back in time from the systolic rise at to', specifically from @t @t @t @t t1 - 2 to tl + 1. ; from t2 - 2 to t2 + @t/2 2 and generally from tn t At to tn + @t/2 tn 2 as shown in#Figure 8, rather than a single band as in Figure 4. These bands are indicated at 221, 222, 22n and so on. The generator means forming part of the components described in the '872 patent can be readily used or easily modified to provide these different points in time and therefore the different bands 221, 222, 22n and so on. During each measuring band the cuff pressure Pc (dc) is varied in order to find the cuff pressure which results in a maximum change in cuff volume AVmax or maximum p. That cuff pressure corresponds to the patient's actual blood pressure at that point in time in the actual blood pressure curve. Thus, for example, if during the measuring band 221 (tl 2 2t @t/2 to t1 + t2t), p (dc) is found to equal Pbl at a p max than the patient's actual blood pressure at the time t1 (where tl is temporally the center point of band 221) is equal to Pbl. This can be repeated (preferably all in one run) for the measuring bands 222 and 22n and so on for providing pressure points Pb2 to Pbn corresponding to times t2 to tn in the graph of Figure 7 where t2 to tn are temporally the center points of their respective bands. While Figure 8 shows only two such bands along the diastolic decline, they can extend entirely back to the beginning of the pulse (time to), except along any segments of the pulse where the slope is zero, as for example at the systolic pressure point or at the peak of the dichrotic notch, as will be pointed out below. All of the intermediate points (except at zero slopes) between to and t'o can be found in this way. Only if the measuring bands 221, 222 and so on are selected to fall on parts of the waveform of Figure 6 which have finite positive or negative slope, will this procedure be accurate. If by example the measuring band were located at time t4 at a position of zero slope on the waveform of Figure 6, the resulting slope of the cuff pressure pulse at the time t4 would also be zero for all values of the cuff pressure. In this latter case the sensitivity of the method becomes zero when the slope of the true waveform becomes zero. With the exception of all these zero slope points on the waveform; any other position on the waveform at general time tn can be located by observing the general applied cuff pressure Pc (n) at which the slope of the cuff pressure pulse has a maximum at time tn. The observed cuff pressure Pc (n) may then be plotted against tn as a valid point on the waveform. This is made clear in Figure 7 in which the areas of the waveform which are unmeasurable or poorly measurable by this method are indicated by dotted lines. It is also described generally in Link United States Patent 3,903,872, although not in detail. The foregoing has been a discussion of how a particular patient's actual blood pressure waveform can be closely approximated without an invasive device. This may be an important diagnostic tool to a doctor, especially if it turns out that his patient has an irregular waveform. This is best exemplified in Figures 9a-d which diagrammatically illustrate a number of waveforms having different mean values. The mean pressure Pb(M) of a blood pressure waveform is equal to the diastolic blood pressure Pb(D) plus a particular fraction K of the difference between the patient's systolic blood pressure Pb(S) and his diastolic blood pressure. Equation 2A shows this and equation 2B shows the same thing in a convenient short hand notation. Pb(M) P Pb(D) + K(Pb(S) -Pb(D)) ... (2A) M = D + K(S-D) ...(2B) Noting that the mean pressure M can be calculated by integrating the waveform (its pressure amplitude P) over time T (the duration of the waveform) so that: EMI23.1 and: EMI23.2 With the above equations in mind, the Figure 9a waveform can be shown to have a K value (which is commonly referred to as the blood pressure constant) of about 0.50. The Figure 9b waveform approximates a K value of 0.6 while the Figure 9c waveform approximates a K value of 0.2. Finally, the Figure 9d waveform approximates a K value of 0.33. This latter waveform most closely corresponds to a healthy blood pressure waveform and therefore some diagnostic devices of the prior art purport to calculate mean blood pressures by assuming a K value of 0.33. With this assumption of K=0.33 along with the patient's diastolic and systolic blood pressures, a calculation of the mean pressure using equations 2A and B can be done. Of course, this can be quite dangerous if the particular patient actually has a blood pressure constant of, for example, 0.60 or 0.20. However, by generating the approximated waveform illustrated in Figure 7, all guess work regarding the patient's mean blood pressure and blood pressure constant K is eliminated. In fact, once the approximated waveform is determined, it can be integrated electronically so as to calculate the mean pressure Pb(M) which might be helpful to the doctor and from this b the blood pressure constant K can be readily calculated. Suitable means can readily be provided to make these various calculations. As a result of the various aspects of the present invention thus far described, a diagnostic tool can be provided which not only provides a patient's diastolic and systolic blood pressures non-invasively but also provides a close approximation of the patient's actual blood pressure waveform as well as his mean pressure and blood pressure constant, again non-invasively. This tool or arrangement is shown in Figure 10 including suitable cuff means generally indicated at 30 in position around the arm of a patient in the normal operating manner and maintained at different pressure levels from zero pressure to, for example, 160 Torr by suitable means 32. The resultant cuff pulses are monitored by transducer 34. Suitable and readily providable electronic means 35 serve to receive these pulses and from this information can provide the patient's diastolic and systolic blood pressures along with his transformation curve in accordance with the Link and Link et al patents. Means 35 also includes readily providable circuitry for providing the intermediate pressure points at times t1, t2, t3, and so on shown in Figures 6-8 and with this information further readily providable circuitry for graphing the waveform in Figure 7 on an oscilloscope or monitor 36. In addition means 35 can also include circuitry for calculating the mean pressure Pb(M) and blood pressure constant K from this waveform and equations 2-4 above. An actual working embodiment of this overall arrangement is shown by block diagram in Figure 21B which will be discussed hereafter. Having discussed Figures 1-5 in regards to the prior art techniques for obtaining diastolic and systolic blood pressures for a given patient in accordance with the techniques described in the above-recited LINK and LINK et al patents and Figures 6-10 regarding techniques for generating a patient's own blood pressure curve and its mean value, attention is now directed to another aspect of the present invention, in conjunction with Figures 11-14 where: FIGURE 11 graphically displays the peak to peak amplitude A of various cuff pulses of Figure 1A against cuff pressure. FIGURE 12 graphically illustrates a transformation curve corresponding to the one illustrated in Figure 2 but generated from the information in Figures 1A and 11 only. FIGURE 13 illustrates the same curve as Figure 12 normalized to zero volume at negative wall pressures and having superimposed thereon its differentiated curve. FIGURE 14 is a functional illustration of an arrangement for electronically generating the curves of Figure 13. Turning now to Figures 11-14 in conjunction with Figure 1A, attention is directed to a technique for generating a transformation curve for a given individual in accordance with the present invention. As stated previously, Figure 1A illustrates a particular patient's cuff pulses 10a, 10b and so on, as read out on an oscilloscope, for varying applied cuff pressures Pc (dc) starting with a cuff pressure of 160 Torr (pulse 10a) and ending with a cuff pressure of zero (pulse 10q). Note that the peak to peak amplitude (A) of each cuff pulse has been measured and so indicated in Figure 1A. As will be seen below, by using only this information and the patient's diastolic and systolic pressures which may be determined in any suitable manner, for example in accordance with the previously recited Link and Link et al patents, the particular patient's own transformation curve and its derivative (corresponding to his arterial compliance (dV/dPw) curve) can be generated in a way which is different than has been done heretofore. Referring to Figure 11, the peak to peak amplitude values (A) measured from Figure 1A have been graphically plotted against applied cuff pressure and a resultant curve 40 drawn. Using information taken from this curve and the patient's diastolic and systolic blood pressures, the S-shaped transformation curve 42 of Figure 8 may be plotted. In order to more fully understand how this is accomplished, it must be kept in mind that the patient's diastolic and systolic pressures together provide a pulse pressure band (e.g. a measuring band) corresponding to the band 14 illustrated in Figure 2. Assuming the patient's diastolic blood pressure is 80 Torr and his systolic blood pressure is 120 Torr, this band is precisely 40 Torr wide. It must also be kept in mind that the transformation curve 42 is plotted in an x-y coordinate system in which the x-axis (the transmural axis) corresponds to Pw (the wall pressure of the patient's artery) and the y-axis corresponds to relative arterial volume or Pc (ac), as previously described with respect to Figure 2. As a reminder, Pwall 11 Pblood - Scuff or Pw = Pb - Pc (dc). Thus, with a cuff pressure Pc (dc) of zero, the measuring band is between 80 Torr and 120 Torr and the peak to peak amplitude of the cuff pulse is 0.1 Torr which corresponds (is in direct proportion) to the change in arterial volume (AV) resulting from this cuff pressure. In other words, as the patients blood pressure rises and falls within the measuring band of 80 Torr and 120 Torr, V changes an amount so as to produce a cuff pulse amplitude A of 0.1 Torr. This point can be plotted in Figure 12 as point 1 on the transformation curve which transforms variations in blood pressure Pb or wall pressure Pw into cuff pulses #c (ac). At an applied cuff pressure of 40 Torr, the wall pressure Pw oscillates back and forth within the 40 Torr measuring band between 80 Torr and 40 Torr. As seen in Figures 1A, 11 and 12, this results in a peak to peak amplitude of 0.50 Torr and a directly proportionate change in AV. This may be plotted as point 2. Additional points 3, 4 and 5 have been plotted in Figure 12 corresponding to cuff pressures of 80, 120 and 160. While only five points were plotted, it should be understood that points corresponding to all of the cuff pressures actually measured in Figure 1A and even those interpolated from the curve of Figure 11 could have been plotted. From these points, the transformation curve 42 illustrated in Figure 12 can be readily drawn. This curve is reproduced in Figure 13 with the axis corresponding to Pw moved downward, as shown. Once the transformation curve is generated, the patient's differential relationship APc(ac)/aPw or equivalently his compliance curve dV/dPw 43 can be generated by differentiating the transformation curve. It is noted that the oscillometric cuff pulse amplitudes A shown in Figure la often do not become zero for even very large values of the cuff pressure but approach a small and fairly constant value for large cuff pressure. This small value may be subtracted from each of the other amplitude values A in the table of Figure la and graphed in Figure 11. The resulting slightly reduced values A could then be utilized to provide a somewhat improved Pc(acJ/Pw or V/Pw curve by using the method described above. Figure 14 illustrates means 44 for receiving the various cuff pulses corresponding to those in Figure 1A from a given individual through a cuff (45) applied to the individuals arm and a transducer forming part of means 44. Means 44 then extracts the peak to peak information and upon receiving the patient's diastolic and systolic blood pressures from suitable inputs shown in Figure 14 is able to act on this information so as to generate the transformation Pc (ac) vs Pw and its derivative QPc(ac)/APw curves 42 and 43, respectively, which can be permanently recorded or placed on an oscilloscope, as generally indicated at 46. The electronics necessary to make means 44 function in this manner can be readily provided in view of the teachings herein. The block diagram of Figure 21B (to be discussed hereinafter) serves as an actual working embodiment of this arrangement of Figure 14. The foregoing descriptions may be separated into three categories. The description associated with Figures 1-5 corresponds to prior art techniques for obtaining diastolic and systolic blood pressures for a given patient in accordance with the techniques described in the above-recited Link and Link et al patents. The description associated with Figures 6-10 is directed to techniques for generating a patient's own blood pressure curve and its mean value as described and claimed in applicant's parent application serial number 622,213 filed June 19, 1984 and as generally alluded to in Link Patent 3,903,872. Finally, the description associated with Figures 11-14 is directed to techniques for generating the patient's own transformation curve as disclosed and claimed in applicant's own parent application serial number 622,080 filed June 19, 1984. Having provided these descriptions, attention is now directed to still further aspects of the present invention in conjunction with Figures 15-25 where: FIGURES 15a, 15b, 15c and 15d graphically illustrates how a patient is subjected to cuff pressure with time in one down-ramp and three up-ramp modes (hereinafter referred to as down-ramp and up-ramp pressure cycles). FIGURE 16a graphically illustrates a series of down-ramp pressure cycles with time in which each cycle is carried out in accordance with the prior art. FIGURE 16b graphically illustrates a series of up-ramp pressure cycles carried out in accordance with the present invention. FIGURE 17 graphically illustrates a patient's transformation curve (corresponding to any of the transformation curves discussed previously) and a particular cuff pulse curve of the patient superimposed thereon. FIGURE 18 graphically illustrates a curve (corresponding to the curve of Figure 5 in Link Patent 3,903,872) for obtaining the diastolic pressure of the patient. FIGURES 19a, 19b and 19e graphically illustrate three cuff pulses unique to the patient at respective cuff pressures of 50, 60 and 70 Torr. FIGURE 20 graphically illustrates the results of a stat mode of monitoring a particular patients systolic, diastolic and mean pressures over an extended period of time in accordance with the present invention by taking successive measurements at closely spaced intervals but without having to subject the patient to cuff pressures above the systolic level each time. FIGURE 21A functionally illustrates an apparatus for monitoring a patient's systolic, diastolic and mean pressures over an extended period of time by taking successive measurements without having to subject the patient to cuff pressures as high as the patient's systolic pressure each time. FIGURE 21B illustrates a block diagram of an actual working embodiment of the apparatus of Figure 21A (as well as the arrangements of Figures 10, 14 and 25). FIGURE 22 graphically illustrates two curves corresponding to the curve described in Figure 5 of LINK patent 3,903,872 at two different time intervals and over an applied cuff pressure range which includes a maximum cuff pressure which, at all times, is less than the patient's anticipated systolic pressure. FIGURE 23 graphically illustrates a patient's transformation curve corresponding to the previously described transformation curves. FIGURE 24 graphically illustrates the curve which is the integration of the curve of Figure 22 and which thereby corresponds to the patient's transformation curve over the cuff pressure range utilized to generate the curve of Figure 23, and superimposed thereon is the patient's cuff pulse generated at a cuff pressure of 60 Torr. FIGURE 25 functionally illustrates an apparatus for determining certain blood pressure parameters of a given patient including his systolic and diastolic pressures without having to subject the patient to cuff pressures as high as the patient's anticipated systolic pressure. Referring first to Figures 15-21, these Figures correspond to what may be referred to as a rapid or stat mode for monitoring a patient's systolic, diastolic and mean pressures over an extended period of time by taking successive measurements at closely spaced intervals through out the period. Moreover, while this monitoring technique requires that the patient be subjected to elevated cuff pressures over this period, the present invention minimizes the discomfort resulting from being subjected to these pressures. In order to more fully appreciate this, attention is first directed to Figure 15a which graphically illustrates how a patient is subjected to cuff pressure during one full down-ramp cycle. More specifically, as seen in Figure 15a, the horizontal axis represents time while the vertical axis represents the cuff pressure to which the patient is subjected during the full cycle (which is shown to be 20 seconds long). The curve (or full cycle as it will be called) is indicated at 50a and shows that the patient is subjected to an initial pressure pump up and then to a down-ramping pressure starting with a cuff pressure of 170 Torr and ending at a cuff pressure of zero. Figures 15b, c and d illustrate up-ramp cycles to be discussed hereinafter. For purposes herein, it is assumed that curves 50a, 50b, 50c and 50d are linear and can be made so in accordance with devices such as described in applicant's copending European Patent Application No. 85308945.6 filed 9th Daosixr 1985 entitled LINEAR PRESSURIZING AND DEPRES SURIZING DEVICE AND ITS METHOD OF USE (attorney docket number A-41660/SCS). However, it is to be understood that the ramps could also be non-linear as is typical in the prior art. In either case, in accordance with the techniques previously described herein and in the previously recited Link and Link et al patents, it was necessary to subject a given patient to cuff pressures within a range which included the patient's anticipated diastolic and systolic pressures in order to determine these latter pressures and the patient's mean pressure. Thus, if it is assumed that a given patient's diastolic pressure is 80 Torr and his systolic pressure is 140 Torr, heretofore it was necessary to subject the patient to a cuff pressure greater than 140 Torr, for example the 170 Torr level shown in Figure 15a. Thus, it was typical to provide the full cycle ramp shown in this latter figure. Figure 15b illustrates a full cycle also, but in an up-ramp mode. The graphic illustration in Figure 15a not only depicts a typical prior-art full-cycle down-ramp but also can be shown to represent the level of comfort to the patient by taking the areas under the curves. By way of explanation it is reasonable to estimate a patient's discomfort from taking a blood pressure measurement as the product of the cuff pressure and the time of pressurization. Further, by experience, we can assign the time during which the cuff pressure is less than diastolic as mildly discomforting, and during which the cuff pressure is greater than diastolic pressure as greatly discomforting (the artery is being completely collapsed in this high pressure region). These two levels of discomfort are shown in Figures 15a, 15b, 15c, 15d, 16a and 16b. We define the sum of the two discomfort levels as the discomfort coefficient and these are also included in the figures. Thus, the total area under curve 50a is equal to 1960 Torr-seconds. This may be referred to as the patient's "discomfort coefficient". Obviously, the greater this coefficient the less comfortable the patient is. This is especially true if it is necessary to monitor the patient over an extended period of time and thereby subject him to a number of pressure cycles, as illustrated, for example, in Figure 16a. As shown there, the patient's diastolic, systolic and mean pressures (also referred to herein as critical pressures) are monitored over a period of 100 seconds requiring five full cycles of the type illustrated in Figure 15a. Therefore, over this entire extended period, the patient's total discomfort coefficient is equal to 9800 Torr-seconds (5 cycles at 1960 Torr-seconds/cycle). This is typical for existing "down-ramp" machines. As will be seen below, by the technique disclosed herein it is possible to reduce substantially the above described discomfort coefficient over an extended monitoring period while monitoring the same critical pressures throughout this period. This is best illustrated in Figure 16b in conjunction with Figures 15b and 15d. As shown in Figure 16b, the patient is subjected initially to a full up-ramp cycle 50b but is then subjected to reduce up-ramp "stat" cycles 50d shown in Figure 15d. Returning to Figure 15d, the reduced stat cycles 50d is shown and is only 12 seconds long and has a maximum pressure of 90 Torr. Therefore, its discomfort coefficient is 540 Torr-seconds as opposed to the 1500 Torr-second discomfort coefficient of the full cycle SOb. As will be seen hereinafter, once the patient's diastolic and systolic pressures are established as a result of the initial full cycle 50b, it is possible in accordance with the present technique to obtain not only the patient's diastolic pressure but also his systolic pressure and mean pressure as a result of measurements utilizing the smaller stat cycles. It is only necessary that the patient be subjected to a cuff pressure slightly greater than his anticipated diastolic pressure during each of these successive measurements. Thus, as illustrated in Figure 16b, five measurements are in fact made over the same 100 second period illustrated in Figure 16a. However, the total discomfort coefficient is 3740 Torr-seconds rather than 980 Torr-seconds as in the case of Figure 16a. While the stat cycles are illustrated in Figure 16b at spaced intervals in time over the 100 seconds it is certainly possible to obtain a greater number of measurements over the same period or obtain the same number of measurements over a lesser period by generating the stat cycles immediately after one another and after the full cycle 50b. Also, while both the full and stat cycles have been generated as up-ramps, it is to be understood that they could just as easily be generated as down-ramps. In fact, if it is desired, the full cycle mode can be initially provided in duplicate as a back to back up-ramp and down-ramp. In this way, the full cycle or "parameter determining" cycle as it may be referred to can be duplicated in order to obtain two direct measurements for the patient's critical pressures initially. The foregoing discussion of Figures 15a, b, d, 16a and 16b has assumed that it is possible to determine a patient's systolic pressure without having to subject the patient to a cuff pressure at that level, once the patient's systolic pressure is initially measured during a parameter determining cycle. Attention is now directed to Figures 17, 18 and 19a, b, and c in order to understand how this is accomplished. Referring first to Figure 17, the particular patient's transformation curve 54 is illustrated. This curve was previously described herein and, as described, it can be readily generated by subjecting the patient to the full range of cuff pressures corresponding to up-ramp 50b and determining the patient's diastolic and systolic pressures during this up-ramp cycle. Therefore, during the monitoring procedure illustrated in Figure 16b, the patient's particular transformation curve 54 can be generated during the initial full cycle 50b along with the patient's diastolic, systolic and mean pressures. In the following stat cycle (and all of the subsequent stat cycles) it is not possible to obtain the patient's systolic pressure in the same manner since he is not subjected to a cuff pressure at least as great as his systolic pressure. Nevertheless, it is possible to obtain the patient's systolic pressure at that time by using the transformation curve generated during the first cycle, as will be seen. The diastolic pressure is obtained in the manner described in Link patent 3,903,872 utilizing the curve illustrated in Figure 18. As stated previously, this curve corresponds to the curve in Figure 5 of this latter patent for cuff pressures within the stat cycle, that is up to a maximum of 100 Torr. Thus, the horizontal axis represents applied cuff pressures Pc (dc) up to 100 Torr and the vertical axis represents the first derivative (p) of the measured cuff pressure pulses at a specific time in the patient's actual blood pressure pulse or cycle. By generating this curve at the appropriate time in the patient's blood pressure cycle (near the diastolic end point) the patient's diastolic pressure is readily determined. Specifically, as previously described herein and as described in the '872 patent, the applied cuff pressure Pc (dc) responsible for gen erating p max on the curve in Figure 18 (corresponding P the maximum change in arterial volume at the diastolic end point) is equal to the patient's diastolic pressure. Thus, in the curve of Figure 18, it is seen that the patient's diastolic pressure is 80 Torr. During a stat cycle, each time the patients heart beats, a cuff pulse Pc (ac) is generated corresponding to the then applied cuff pressure Pc (dc). These pulses, three of which are illustrated in Figures 19a, 19b and 19c, are used to generate the curve of Figure 18 to determine the patients diastolic pressure. At least one of these cuff pulses is used in conjunction with the patient's transformation curve 54 illustrated in Figure 17 and the patient's diastolic pressure of 80 Torr produced as a result of the curve in Figure 18 to determine the patient's systolic pressure during that cycle. Returning to Figure 17, attention is directed to the way in which this is accomplished. Specifically, let it be assumed that the cuff pulse 56a generated at a cuff pressure of 50 Torr, as illustrated in Figure 19a, is used in conjunction with the transformation curve and the patient's diastolic pressure. At the outset, it is necessary to locate the base of the cuff pulse 56a (its diastolic level) on the vertical axis of the transformation curve 54. To this end, the transmural pressure on the horizontal axis (Pw) corresponding to the patient's diastolic pressure at a cuff pressure of 50 Torr is located. This point is the diastolic blood pressure of the patient minus the cuff pressure or 80 Torr minus 50 Torr which is 30 Torr. This 30 Torr point is located as illustrated in Figure 17 and a vertical line 57 (actually a series of arrows) is drawn up to the point at which it intersects the transformation curve. That point determines the horizontal base of the cuff pulse 56a of Figure 19a, as indicated by horizontal line 58. The cuff pulse is set on line 58 as shown. Thereafter, a horizontal line 60 is generated from the systolic level of the cuff pulse to the transformation curve. At the point of intersection of this latter curve with line 60, a further vertical line 62 is drawn downward to its point of intersection with the transmural pressure axis. As illustrated, this point of intersection is at 90 Torr. This 90 Torr value corresponds to P as described w previously at a cuff pressure Pc (dc) of 50 Torr. Thus, the patient's actual blood pressure at this point (which corresponds to his systolic pressure) is the 90 Torr value plus the cuff pressure of 50 Torr or 140 Torr (Pw + Pc (dc) = Pb). In view of the foregoing, it should be apparent that the systolic pressure of a patient can be obtained during a stat cycle, that is, without subjecting the patient to pressures as high as his systolic pressure so long as a prior parameter determining full cycle is carried out to determine the patient's systolic pressure directly at least once in order to generate the transformation curve 54. For purposes of accuracy it may be desirable to carry out the procedure described immediately above for obtaining the patient's systolic pressure using additional cuff pulses at other pressures, for example cuff pulses 56b and 56c in addition to the cuff pulse 56a. If the systolic pressures obtained from these different measurements are different, they can be averaged to provide an average systolic pressure. At the same time, once the patient's diastolic and systolic pressures are determined as a result of the stat cycle, techniques previously described herein can be utilized to obtain the patient's mean pressure during that same stat cycle i.e., the entire cuff pulse curve 56a can be transformed through the transformation curve 54 and the mean blood pressure curve obtained by integration. Figure 20 graphically illustrates the results of the monitoring procedure just described. The horizontal axis represents time and the vertical axis represents the patient's diastolic, mean and systolic pressures at different times corresponding to the different measurements. The first measurement corresponds to a full cycle mode while the subsequent ones may correspond to stat modes or it may be desirable to provide a full cycle mode periodically in order to reconfirm or modify the patient's transformation curve 54. In either case, the patient is subjected to a lower discomfort coefficient then would be the case if each measurement required a full operating cycle. Referring now to Figure 21A, this Figure functionally illustrates an apparatus 64 for carrying out the procedure just described. This apparatus includes a suitable blood pressure cuff 66 positioned at the appropriate location adjacent an artery of a patient. Means generally indicated at 68 are provided for pressurizing the cuff to different levels sufficient to provide the full cycle 50b and the stat cycle 50d. The resultant cuff pulses including those illustrated in Figures 19a, b, and c are produced by suitable circuitry 70 capable of holding the cuff pulses including, for example, those illustrated in Figures l9a, b and c, in memory. Circuitry generally indicated at 72 is responsive to the cuff pulses produced during the initial parameter determining cycle for determining the patient's diastolic and systolic pressures during that cycle. These values and the cuff pulses produced by circuitry 70 are input to circuitry 74 for generating the patient's transformation curve which is stored in memory therein. At the same time, circuitry 74 includes suitable means for determining the patient's mean pressure during the parameter determining cycle. During each of the subsequent stat cycles, means 68 pressurizes cuff 66 to provide the stat cycle 50d and circuitry 70 produces the corresponding cuff pulses. Circuitry 72 is responsive to these cuff pulses for determining the patient's diastolic pressure only since the cuff 66 is not pressurized to a sufficiently high level to determine the patient's systolic pressure. The diastolic pressure determined during this stat cycle is input to circuitry 76 along with the cuff pulses from circuitry 70 for at least one or a group of the cuff pulses such as those illustrated in Figures l9a, b and c and the patient's transformation curve is held in the memory of circuitry 74. Circuitry 76 acts on this information to determine the patient's systolic blood pressure by carrying out the procedure described with regard to Figure 17. This pressure value may be fed back into circuitry 74 so that the latter can also provide the patient's mean pressure during this latter cycle. As indicated above, Figure 21a is a functional illustration of an apparatus 64 for carrying out the technique associated with Figures 15-20. Figure 21b is a block diagram of an actual working embodiment of this apparatus, which in Figure 21b is indicated at 64'. The apparatus shown there (in block diagram) includes a blood pressure cuff or pressure pad 66' positioned at an appropriate location around (in the case of a cuff) or adjacent (in the case of a pad) a suitable artery of a patient. In this latter regard, it is to be understood that either a cuff or a pad may be utilized. For purposes herein, where reference is made to a cuff only, it is to be understood that a pad could be readily substituted therefore, although a different artery may have to be selected. A pump and suitable pneumatic controls generally indicated at 68' are provided for pressurizing the cuff (or pad) to different pressure levels sufficient to provide the full up-ramp cycle 50b and the stat cycle SOd illustrated in Figures 15b and d, respectively, or any other type of cycle such as the cycle 50a and 50c illustrated in Figures 15a and c, respectively. A pressure transducer illustrated at 69' couples the cuff or pressure pad to a combination of amplifiers and band pass filters generally indicated at 70' for producing cuff pulses such as the ones illustrated in Figures 19a, b, and c. An analog MUX, an A/D converter and a 16-bit microcomputer (or any other suitable computer means) indicated generally at 71', 72' and 73', respectively, interconnected in the manner illustrated in Figure 21b, cooperate to provide means for digitizing the analog cuff pressures, i.e., Pc (ac) and #c (dc). The microcomputer or computer generally is controlled by a suitable program stored in ROM 74' in order to carry out the necessary steps of the overall apparatus 64'. This program may vary in length from for example lk bytes to as much as 32k bytes, depending on accuracy and other factors. The digitized value of cuff pressure Pc (ac) and Pc (dc) and other necessary information, e.g., the transformation curve generated during each initial parameter determining cycle, are stored by the computer 73' in a RAM 75'. The computer having calculated the various blood pressures, outputs the results to a monitor 76', printer 77', LED display 78' or perhaps to another computer 79'. It can be seen that the RAM memory 75' must be sufficiently large to store the various cuff pulses as well as the transformation curves described above. The block diagram illustrated in Figure 21b has been described specifically with respect to apparatus 64', that is, as an apparatus for carrying out the technique associated with Figures 15-21a. However, it is to be understood that this same arrangement illustrated in Figure 21b may serve as an actual working embodiment for carrying out the functional steps associated with the arrangements of Figures 10 and 14. In the case of the arrangement of Figure 10, the ROM 74' would contain a suitable program for operating the microcomputer or computer 73' so as to act on the digitized cuff pressures in a way which produces the necessary information to generate and output the curve of Figure 7. In the case of the arrangement of Figure 14, a suitable program would be contained in the RAM to operate the microcomputer or computer in order to generate the transformation curve of Figure 12. Also, as will be seen hereinafter, the same components forming arrangement 64' with still another program serves as an actual working embodiment for the technique to be described hereinafter with regard to Figures 22-25. The foregoing discussion in conjunction with Figures 15-21A, B has related to a technique for monitoring a patient's diastolic, systolic and mean pressures over an extended period of time by taking successive measurements at closely spaced intervals throughout the period and without having to subject the patient to high cuff pressures (on the order of his systolic pressure), except initially during a parameter determining cycle. The following technique to be described below in conjunction with Figures 22-25 does not require even one high pressure cycle. More specifically, the following is a technique for obtaining a patient's diastolic, mean and systolic pressures without ever having to subject the patient to cuff pressures on the order of his systolic pressure. In order to understand how this technique is achieved, attention is redirected to the previously described Link United States Patent 3,903,872. It may be recalled from this patent and particularly the discussions associated with Figure 5 thereof as well as the discussions provided herein that the actual blood pressure of a given patient at any point along the patient's actual blood pressure curve can be determined by measuring p at that time as the patient is subjected to different cuff pressures. In the case of the present technique, the patient is subjected to cuff pressures only somewhat greater than the anticipated diastolic pressure of the patient and, in any event, pressures which are less than the patient's systolic pressure. The up-ramp cycle of Figure 15c is illustrative of such pressures. Note that the patient during this cycle is subjected to at most about 120 Torr. In accordance with this technique, it is first necessary to select two points in time tl and t2 on the diastolic decline of the patient's actual blood pressure waveform. Once these points in time are selected, the patient's blood pressure cuff is varied through a range of pressures below the anticipated systolic pressure of the patient but including levels above and below the anticipated blood pressures of the patient at the selected points in time tl and t2 on his actual waveform, thereby producing cuff pulses at these different pressure levels. The closer the selected times tl and t2 are to the diastolic point in time on the patient's waveform, the lower the maximum cuff pressure need be. On the other hand the closer t1 and t2 are together the larger will be the errors resulting from the present technique (the subtraction of two large numbers). Because of the conflicting requirements above, a choice of tl near diastolic and of t2 about half way toward systolic is reasonable. Thus, if the actual anticipated blood pressure at time tl is near the diastolic point in the waveform and if the anticipated pressure at t2 is about midway between systolic and diastolic pressure, it would be necessary only to subject the patient to cuff pressures slightly greater than midway between systolic and diastolic pressure. In any event, once these points in time are selected and the patient is subjected to these cuff pressures, the two curves 64 and 66 illustrated in Figure 22 can be generated. The solid line curve corresponds to p at the time t1 and the dotted line p curve corresponds to p at t2. Actually, tl is thet P 2 Actually, t1 is the temporal center for the band Atl illustrated in Figure 23 and t2 is the temporal center for the band At2 in Figure 23. The maximum value for each of these curves determines the patient's actual blood pressure at the associated time t1 or t2. Thus, in Figure 22, it can be seen that the patient's blood pressure at the time t1 in his waveform is 80 Torr (indicated at D1) and the pressure at time t2 is 100 Torr (D2). Figure 23 diagrammatically illustrates the patient's transformation curve in association with his actual blood pressure pulses in order to illustrate the relationship between time tl and its associated band Art1. Note that the band is located within the diastolic decline of the actual blood pressure pulse. As the patient is subjected to increasing cuff pressures, the resultant time derivative of the measured cuff pulse (p) first increases and then decreases, thereby resulting in the curve 64 of Figure 22. This would also be true for t2 and At2 resulting in curve 66 of Figure 22, where Atr is shown up from Atl on the diastolic decline. Once either of the curves in Figure 22 is generated,for example curve 64, it can be integrated to provide the patient's transformation curve which is generally indicated by the reference numeral 80 in Figures 23 and 24. This curve is placed in the coordinate system shown such that the vertical axis at zero transmural pressure extends through the center of its maximum slope for the reasons to be discussed below and such that the horizontal axis is located near the bottom of the curve, although this is not critical. Note that the horizontal or transmural pressure axis corresponds to P which is w equal to the actual blood pressure Pb minus the applied cuff pressure #c (dc). Also note that the patient was subjected to a maximum cuff pressure of 120 Torr and therefore the horizontal axis of the transformation curve goes a limited distance to the left of the vertical axis depending on the patient's diastolic pressure Nevertheless, it is not necessary to go any further to the left for purposes of the present technique, as will be seen. The transformation curve 80 is obtained by integrating over curve 64 according to the procedures described above. The vertical axis at 80 Torr for curve 64 becomes the zero axis for curve 80. The corresponding values are shown in Figure 23. Thus, keeping the definition Pw Z Pb - P (dc) in mind, when Pb is minimum (at 80 Torr) and #c (dc) is equal to 80 Torr, Pw = 0; when #c (dc) =10 Torr then Pw = 70 Torr and so on. Having generated the transformation curve 80 in Figures 23 and 24, attention is now directed to the way in which the patient's diastolic and systolic pressures are determined using this curve in combination with the pressure values D1 and D2 determined by means of the curves illustrated in Figure 22. At the outset, it is necessary to select one of the cuff pulses Pc (ac) generated in order to provide the curves of Figure 22. Any such pulse will do, for example the cuff pulse produced at a cuff pressure of 60 Torr. The pressure points D1 and D2 are located on this cuff pulse by locating the times t1 and t2. This can be done by moving back from the diastolic end of the cuff pulse the appropriate amount of time. This cuff pulse including the pressure points D1 and D2 is illustrated in Figure 24 at 81. At the same time, the D1 and D2 points are located on the horizontal Pw axis of the transformation curve for a cuff pressure of 60 Torr. Since D1 equals 80 Torr, the point on the horizontal P axis correspond w ing to this point is 20 Torr (80 Torr minus 60 Torr). Since D2 equals 100 Torr, the D2 point on the horizontal P axis is 40 Torr (100 Torr minus 60 Torr). w Once the D1 and D2 points are located on the horizontal axis of the transformation curve, vertical lines 82 and 84 are drawn upwardly from these points until they intersect the transformation curve. Horizontal lines 86 and 88 are then drawn from these intersecting points to the left, as illustrated. At the same time, vertical lines 90 and 92 are drawn from the points D1 and D2 on the cuff pulse 81 illustrated in Figure 24 until they intersect lines 86 and 88 respectively at the two points D11 and D2, respectively as seen in Figure 24. The entire cuff pulse 81 can then be scaled to match points D11 and D2' as indicated by means of the dotted lines to provide the appropriately scaled reproduction pulse 81'. In other words, each section of the reproduced cuff pulse 81' in Figure 24 is proportionate to the corresponding section of the original cuff pulse 81 but scaled to match the points D1' and D2'. From the base of the scaled cuff pulse 81'; the diastolic pressure of the patient can be determined by finding the point of intersection of the transformation curve 80 with the horizontal line 100. From this intersecting point, the vertical line 102 is drawn downward until it intersects the horizontal Pw axis of the transformation curve. It does so at a transmural pressure (Pw) of 10 Torr. Therefore, the diastolic pressure is equal to 70 Torr (10 Torr plus 60 Torr where Pb = P + P (dc)). The same procedure may be used to w w c determine the patient's systolic pressure. More specifically, a horizontal line 104 is drawn from the top of the scaled pulse to an intersecting point of the transformation curve, at which point the vertically downward line 106 is drawn until it intersects the horizontal axis of the transformation curve. It does so at 60 Torr. Therefore, the systolic pressure is equal to 120 Torr (60 Torr plus 60 Torr). The foregoing procedure could be repeated for cuff pulses at different applied cuff pressures and the results could be averaged to obtain averaged values for the systolic and diastolic pressures. Moreover, D1 could be selected at a time tl sufficiently close to the patient's diastolic pressure so that D1 automatically provides the patient's diastolic pressure and it is mainly necessary to carry out the foregoing procedure to provide the systolic pressure. Moreover, this procedure can be repeated successively over a period of time in order to monitor the patient's diastolic and systolic blood pressures over a period of time without ever subjecting the patient to cuff pressures much greater than midway between the patient's systolic and diastolic pressures. The entire pulse 81' can now be transformed through the transformation curve 80 to obtain the transformed blood pressure pulse 81'' shown in dot-dash fashion in Figure 24. Every pressure on the transformed blood pressure pulse 81'' is now known and the mean blood pressure can now be calculated by integration and the entire waveform 81'' can be presented on a suitable monitor. For added accuracy additional points D3, D4 ---D can be included on curve 81 by an analysis identical to the above. Referring to Figure 25, attention is now directed to an over-all apparatus 110 for carrying out the technique described with regard to Figures 22-24. This apparatus includes a blood pressure cuff or pad 112 positioned adjacent a suitable artery of the patient. Means generally indicated at 114 are provided for placing the cuff at different pressure levels below the anticipated systolic pressure of the patient but including levels above and below the anticipated pressures of the patient at the selected points in time tl and t2 on his actual waveform. Circuitry generally indicated at 116 is provided for producing cuff pulses at these different pressure levels. These cuff pulses are input to circuitry 118 which responds thereto for producing the pressure values at D1 and D2 and at the same time this circuitry generates the curves of Figure 22. One of these curves is input to circuitry 120 which integrates the curve and provides the transformation curve 80 as a result thereof. Finally, circuitry 122 utilizes this transformation curve, the pressures D1 and D2 and at least one of the cuff pulses (for example cuff pulse 81) to (1) establish the positional relationship between the transformation curve and selected cuff pulse and (2) the correct scaling of the latter relative to the transformation curve (thereby producing reproduction pulse 81'). Thereafter, circuitry 122 uses the correctly scaled reproduced cuff pulse 81' and its positional relationship with regard to the transformation curve to determine the systolic pressure of the patient and his diastolic pressure, if the latter is not the blood pressures D1 or D2. The discussion immediately above has been a functional description of an arrangement 110 for carrying out the technique associated with Figures 22-24. In a preferred embodiment, this is carried out by means of the components making up the block diagram illustrated in Figure 21b. The cuff or pressure pad 66' in combination with pump and pneumatic control 68', pressure transducer 69' and amplifier and band pass filter 70' together provide cuff pulses as the patient is subjected to the up-ramp cycle of Figure 15c. The analog MUX and the A/D converter 71' and 72' digitizes this information and inputs it to the microcomputer or computer 73'. A suitable program in ROM 74' operates the microcomputer or computer so as to produce the curves 64 and 66 of Figure 22, it determines the pressures at D1 and D2 and it generates the transformation curve 80, then carries out the steps associated with Figure 24 in order to obtain the patient's diastolic and systolic pressure and also the patient's full blood pressure waveform (the waveform 81'' in Figure 24). In the last mentioned technique the points D1 and D2 were selected to lie on the diastolic decline of the blood pressure waveform. However, it should be apparent that points D1 and D2 can be located at any two points on the blood pressure waveform provided that the blood pressure difference between the two points is reasonably large. Specifically the two points can be chosen on the systolic rise part of the waveform between the diastolic end point of the previous pulse and the systolic peak of the current pulse. All the descriptions of this last mentioned technique hold true for these two points except that the polarity of the differential quantities AV and APc (ac) reverses. In this latter technique described with respect to Figures 22-24, the patient was subjected to cuff pressures between the diastolic and systolic pressures as contrasted wtih pressures well above systolic when using prior art techniques. This resulted in the advantage of decreasing the discomfort to the patient due to the subjected cuff pressures, as compared to those techniques which require higher pressures. As an additional advantage, the present technique is more accurate at all pressure ranges. This is because the lower cuff pressures do not fully collapse the artery being monitored, even at the highest cuff pressures (e.g. 120 Torr). An open artery has more sensitivity to the blood pressure within than a collapsed artery. Furthermore, the frequency response of an open artery is certainly higher than a collapsed artery. In the case of battery operated instruments a further advantage resides in the reduction in consumption of energy by the air pump used to pressurize the pressure cuff or pad. Thus, the present technique combines improved patient comfort, improved accuracy and the need for less power.

Claims: WHAT IS CLAIMED IS: 1. A method of monitoring certain blood pressure parameters of a patient including his systolic and diastolic pressures over an extended period of time by taking successive measurements at closely spaced intervals throughout said periods, said method comprising the steps of: (a) taking an initial measurement at the beginning of said period by (i) positioning a pressurizable blood pressure cuff or pad means at the appropriate location adjacent a suitable artery of the patient, (ii) maintaining said cuff or pad means at different pressure levels including levels at and above the anticipated diastolic and systolic pressures of the patient, (iii) producing cuff pulses corresponding to said different pressure levels, (iv) from said cuff pulses, determining the diastolic and systolic pressures of the patient, and (v) from said cuff pulses and the diastolic and systolic pressures of the patient, generating a transformation curve unique to the patient; and (h) taking at least one subsequent measurement during said extended period while said cuff or pad means is still in position adjacent said artery b (i) maintaining said cuff or pad means at different pressure levels including levels at and abode the anticipated diastolic pressure of the patient but below the patient's systolic pressure, as determined by said initial measurement, (ii) producing cuff pulses corresponding to these last-mentioned pressure levels, (iii) from said last-mentioned cuff pulses, determining the patient's diastolic pressure, and (iv) from said last-mentioned cuff pulses, the patient's diastolic pressure and from his transforinatier curve generated during said initial measurement, determining the patient's systolic pressure. 2. A method according to Claim 1 wherein said subsequent measurement is successively repeated a plurality of times after said initial measurement is taken at spaced intervals throughout said extended period, whereby the systolic pressure of the patient is mcnitored throughout said period without having to pressure ize the blood pressure cuff or pad means to a level at or above the patients systolic pressure except during said initial measurement. 3. A method according to Claim 2 wherein, during each of said subsequent measurements, said cuff or pad means is maintained at an uppermost level which is only somewhat greater than the patient's diastolic level, whereby to minimize the pressure subjected to the patient. 4. A method according to Claim 2 or Claim 3 wherein each of said measurements includes generating a blood pressure-like curve corresponding to the patient's actual blood pressure versus time curve from the diastolic and systolic pressures of the patient and his initial 1'; generated transformation curve and thereafter calculat ing the patient's mean pressure from his blood pres sure-like curve during that measurement. 5. A method according to Claim 4 including the step of recording, either temporarily or permanently, the diastolic, mean and systolic pressures of the patient during each of said measurements. 6. A method according to any of Claims 1 to 5 wherein the patient's systolic pressure is determined during said subsequent measurement by (i) selecting at least one cuff pulse produced during said subsequent measurement, (ii) usirs the diastolic pressure of the patient determined during said subsequent measurement, locating the base and peak of said selected cuff pulse on the vertical axis of the patient's transformation curve, and (iii) from the peak point of said selected cuff pulse on the vertical axis of said transformation curve and using the latter curve, locating the systolic pressure of said patient. 7. An apparatus for monitoring certain blood pressure parameters of a patient including his systolic and diastolic pressures over an extended period of time by taking successive measurements at closely spaced intervals throughout said periods, said apparatus compris- ing: (a) means for taking an initial measurement at the beginning of said period, said initial measurement taking means including (i) a pressurizable blood pressure cuff or pad means positionable at the appropriate location adjacent a suitable artery of the patient. (ii) means for maintaining said cuff or pad means at different pressure levels including levels at and above the anticipated diastolic an systolic pressures of the patient, (iii) means of producing cuff pulses corresponding to said different pressure levels, (iv) means for determining the diastolic and systolic pressures of the patient from said cuff pulses, and (v) means for generating a transformatior curve unique to the patient from said cuff pulses and the diastolic and systolic pressures of the patient; and (b) means for taking at least one subsequent measurement during said extended period while said cuff or pad means is still in position adjacent said artery, said subsequent measurement taking means including (i) means for maintaining said cuff or pad means at different pressure levels including levels at and above the anticipated diastolic pressure of the patient but below the patient's systolic pressure, as determined by said initial measurement, (ii) means for producing cuff pulses corresponding to these last-mentioned pressure levels, (iii) means for determining the patient's diastolic pressure from said last-mentioned cuff pulses, and (iv) means for determining the patiert's systolic pressure from said last-mentioned cuff pulses, the patient's diastolic pressure and from his transformation curve, generated during said initial measurement. 8. An apparatus according to Claim 7 wherein said subsequent measurement taking means is adapted to successively repeat said subsequent measurements a plurality of times after said initial measurement is taken at spaced intervals throughout said extended period, whereby the systolic pressure of the patient is monitored throughout said period without having to pressurize the blood pressure cuff or pad means to a level at or above the patient's systolic pressure except during said initial measurement. 9. An apparatus according to Claim 8 including means for generating a blood pressure-like curve corresponding to the patient's actual blood pressure versus time curve from the diastolic and systolic pressures of the patient and his initially generated transformation curve during each of said measurements and thereafter calculating the patient's means pressure from his blood pressure-like curve during that measurement. 10. A method of obtaining certain blood pressure parameters of a given patient including his systolic and diastolic pressures, comprising the steps of: (a) positioning a blood pressure cuff or pad means at the appropriate location adjacent a suitable artery of the patient; (b) selecting first and second points in time t1 and t2 on the diastolic decline or systolic rise of the patient's actual blood pressure waveform below the patient's anticipated systolic pressure; (c) placing said cuff or pad means at different pressure levels including levels above and below the anticipated blood pressures of the patient at the selected points in time t1 and t2 on his actual waveform; and thereby producing cuff pulses at said different pressure levels; (d) from said cuff pulses, measuring the change in cuff pressure ssP at each of said different levels of cuff pressure for relatively narrow first and second intervals of time Atl and Et2 containing times t1 and t2, respectively, on the patient's actual blood pressure waveform; (e) generating a transformation curve unique to said patient from at least some of said measurements; (f) determining the actual blood pressures D1 and D2 of the patient at times t1 and t2, respectively, on the patient's waveform from said measurements; ; (g) selecting a cuff pulse at one of said differ ent levels of cuff pressure and, using said transforration curve and said actual blood pressures, D1 and D2, establishing the positional relationship between said transformation curve and selected cuff pulse and the correct scaling of the latter relative to said transformation curve; and (h) from said correctly scaled cuff pulse and from its positional relationship with said transformation curve, determining the systolic pressure of the patient and his diastolic pressure, if the latter is not blood pressures D1 or D2. 11. A method according to Claim 10 wherein the first point in time tl is selected to be in close proximity to the beginning of the systolic rise portion of the patient's actual blood pressure waveform, whereby D1 corresponds nearly to the patient's diastolic pressure. 12. A method accord ing to Claim 10 or Claim 11 wherein said transformation curve is generated by integrating over time the measurements AP at each of said different levels of cuff pressure for only one of said intervals of time At and bt2. -13. A method according to Claim 10 or Claim 11 wherein said transformation curve is generated by integrating over time the measurements SP at each of said different levels of cuff pressure for each of said intervals of time tt1 and bt and averaging the integrated measurements at each pressure level to produce an averaged transformation curve. 14 A method according to any of Claims 10 to 13 including the step of determining the blood pressures of said patient at a sufficient number of points in time other than tl and t2 from said correctly scaled cuff pulse and from its positional relationship with said transformation curve to reproduce the actual blood pressure waveform of said patient. 15. A method according to any of Claims 10 to 14 wherein said steps (a)-(h) are repeated at spaced-apart intervals over an extended period of time, whereby to monitor the patients diastolic and systolic blood pressures over said period of time. 16. An apparatus for obtaining certain blood pressure parameters of a given patient including his systolic and diastolic pressures, comprising: (a) a blood pressure cuff or pad means positioned at the appropriate location adjacent a suitable artery of the patient; (b) means for placing said cuff at different pressure levels below the anticipated systolic pressure of the patient hut including levels above and below the anticipated blood pressures of the patient at selected first and second points in time tl and t2 on the diastolic decline or systolic rise of his actual blood pressure waveform; and thereby producing cuff pulses at said different pressure levels; (c) means responsive to said cuff pulses for measuring the change in cuff pressure bP at each of said different levels of cuff pressure for relatively narrow first and second intervals of time sstl and #t2 containing times t1 and t2, respectively, on the diastolic decline of the patient's actual blood pressure waveform: : (d) means for generating a transformation curve unique to said patient from at least some of said measurements; (e) means of determining the actual blood pressures D1 and D2 of the patient at times from said measurements; (f) means responsive to a selected one of said cuff pulses, said transformation curve and said actual blood pressures D1 and D2 for establishing the positional relationship between said transformation curve and selected cuff pulse and the correct scaling of the latter relative to said transformation curve; and (g) means responsive to said correctly scaled cuff pulse an its positional relationship with said transformation curve for determining the systolic pressure of the patient and his diastolic pressure if the latter is not blood pressures D1 or D2. 17. An apparatus according to Claim 16 wherein the first point in time tl is selected to be in close proximity to the beginning of the systolic rise portion of the patient's actual blood pressure waveform, whereby D1 corresponds closely to the patients diastolic pressure. 18. An apparatus according to Claim 16 or Claim 17 wherein said transformation curve generating means includes means for integrating over time the measurements AP at each of said different levels of cuff pressure for only one of said intervals of time Etl and At2. 19. An apparatus according to Claim 16 or Claim 17 wherein said transformation curve generating means includes means for integrating over time the measurements LP at each of said different levels of cuff pressure for each of said intervals of time btl and At2 and means for averaging the integrated measurements at each pressure level to produce an averaged transformation curve. 20. An apparatus according to any of Clai ms 16 to 19 including means for determining the blood pressures of said patient at a sufficient number of points in time other than tl and t2 from said correctly scaled cuff pulse and from its positional relationship with said transformation curve to reproduce the actual blood pressure waveform of said patient. 21. A method of obtaining certain blood pressure parameters of a given patient including his systolic and diastolic pressures, comprising the steps of: (a) positioning a blood pressure cuff or. pad means at the appropriate location adjacent a suitable artery of the patient; (b) selecting first and second points in time t and t2 on the patient's actual blood pressure wave'ore below the patient's anticipated systolic pressure; (c) placing said cuff or pad means at different pressure levels including levels above and below the anticipated blood pressures of the patient at the selected points in time t1 and t2 on his actual waveform, and thereby producing cuff pulses at said different pressure levels; ; (d) from said cuff pulses, measuring the change in cuff pressure AP at each of said different levels of cuff pressure for relatively narrow first and second intervals of time btl and #t2 containing times tl and t2, respectively, on the patient's actual blood pressure waveform; (e) from said cuff pulses and cuff pressures LP, generating information sufficient to provide the patient's systolic pressure; and (f) from said other information determining the patient's systolic pressure. 22. An apparatus for obtaining certain blood pressure parameters of a given patient including his sytolic and diastolic pressures, comprising: (a) a blood pressure cuff or pad means positioned at the appropriate location adjacent a suitable artery of the patient; (b) means for placing said cuff at different pressure levels below the anticipated systolic pressure of the patient but including levels above and below the anticipated blood pressures of the patient at selected first and second points in time t1 and t2 on his actual blood pressure waveform, and thereby producing cff pulses at said different pressure levels; ; (c) means responsive to said cuff pulses for measuring the change in cuff pressure #P at each of said different levels of cuff pressure for relatively narrow first and second intervals of ttl and bt2 containing times tl and t2, respectively, on the diastolic decline of the patient's actual blood pressure waveform; (d) means responsive to said cuff pulses and said cuff pressures AP for generating information sufficient to provide the patient's systolic pressure; and (e) means responsive to said information to determine the patient's systolic pressure.

Inventors: LINK, WILLIAM T.
Applicants: BAXTER INTERNATIONAL INC. (A DELAWARE CORPORATION)
Application year: 1985
Main classification: A61B5
IPC codes: A61B5, G06F17