AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH

Abstract: An insecticidal and miticidal composition in which 2-dimethylamino-5,6-dimethylpyrimidin-4-yl dimethylcar­ bamate and at least one organic phosphorus compound, methylcarbamate compound, or pyrethroid compound are mixed with an inert carrier.

Description: MITSUI TOATSU CHEMICALS, INC., Tokyo/Japan Specification An insecticidal and miticidal composition which contains a carbamate and an organic phosphorus compound, and a method of controlling insects and mites therewith This invention relates to improved ins;cticidal and miticidal compositions and, more particularly, to such compositions containing 2-dimetylamino-5,6-dimetylpyrimidin-4-yl dimetyl carbamate and at least one compound selected from organic phosphorus compounds, methylcarbamate compounds, and pyrthroid compounds. The term "organic phosphorus compounds" as ubed herein comprehends well-known organic phosphorus insecticides such as S-[1,2-bis(ethoxycarbonyl)ethyl] dimethyl phosphorothiolthioate (Malathon), dimethyl 4-nitro-m-tolyl phosphorothioate (MEP), S-[&alpha; ;(ethoxycarbonyl)ethyl] dimethyl phosphorothiolthioate (PAP), dimethyl 4-methylthio-m-tolyl phosphorothioate (MPP) ,di- ethyl 2,3-dihydro-3-oxo-2-phenyl-6-piridazinyl-phosphorothiate (Pyridaphenthion),diethyl 2-isopropyl-6-methyl-4-piyrimidyl phosphorothioate (Diazinon), O,S-dimethyl N-acetylphosphoroamidothioate (AcePhate), dipropyl p-methylthiophenyl phosphate (Propaphos), 2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate (CVMP), dimethyl ¯S-(N-metylcarbamoylmethyl) phosphorothiolthioate (Dimethoate), l-phpnyl-112,4-triazol-3-yl O,O-diethyl thionophoaphate (Triazophos), 0,0-diethyl-0-(2-quinonxalyl) phosphorothioate (Quinalphos), -cyanophenyl dimethyl phosphorothioate (CYAP), S-(2-acetamidoethyl) dim3thyl phosphorothiolthioate (DAEP), diethyl S-(2-ethylthioethyl) phosphorothiolthioate (Ethylthiometon)- dimethyl S-/2-(1-metylcarbamoylethylthio) ethyl phosphorothioate (Bamidothion), ±-cyanophenyl ethyl phenyl phosphorothioate (CYP), 2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate (CVP), 2-methoxy-4H-1,3,2-benzodioxaphosphorin-2-sulfide (Salithion), 2,2-dichiorovinyl dimethyl phosphate (DDVP), S-p-chlorophenyl dimethyl phosphorothioate (DMCP), dimethyl 2,2,2-trichloro-l-hydroxyethyl phosphonate (DEP), dimethyl 3,5,6-trichloro-2-pyridyl phosphorothionate (Chlorpyriphosmethyl), dimethyl S-phthalimidomethyl phos > horo- thiolothionate (PMP), ethyl p-nitrophenyl phenyl phosphonothionate (EPN), liethyl 3,5,6-trichloro-2-pyridyl phosphorothionate (Chlorpyriphos), diethyl 5-phenyl-3-isoxazolyl phosphorothionate (Isoxathion), S-(N-formyl-N-methylcarbamoylmethyl) dimethyl phosphorothiolothionate (Formothion), S-(2-ethylthioethyl) dimethyl phosphorothiolthiorate (Thiometon), S-2-(isopropylthio)ethyl dimethyl phosphorothiolothionate (Isothionate), S-(4,6-diamino-1,3,5-triazin-2-ylmethyl) dimethyl phosphorothiolothionate (Menazon), 0-(2-diethylamino-6 methylpyrimidin--4-yl) O,O-dimethyl phosphorothioate (Pyrimi phosmethyl)1 2-diethylamino-6-methyl-4-pyrimidinyl diethyl phosphorothionate (Pyrimiphosetlyl), 2-Diethylamino-6-methylpyrimidin-4-yl-dimethyl phosphorothioate (Pirimiphos dimethyl), and the like; and well-known organic phosphorous germicides such as S-benzyl diisopropyl phosphorothiolate (IBP), O-ethyl diphenyl phosphorodithiolate (EDDP), and the like. The term "methylcarbamate compounds" as used herein comprehends well-known carbamate compounds such as m-tolyl methylcarbamate (MTMC), o-cumenylmethylcarbamate (MIPC), o-sec-butylphenyl methylcarbamate (BPMC), o-isopropoxyphenyl methylcarbamate (PHC), 3,4-xylyl methylcarbamate (MPMC), 3,5-xylyl methylcarbamate (XMC), l-naphthyl methylcarbamate (NAC), 3-tolyl S-n-pro- pylcarb;^mate (MTMC-Z), and the like The term "pyrethroid compounds" as used herein comprehends wellknown pyrethroid insecticides such as oc;-cyano-3-phenoxybenzyl- &alpha;-isopropyl-p-chlorophenylacetate (Phenvalerate), 3-phenoxy benzyl-2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane-1-carb- oxylate (Permthrin) &alpha; ;-cyano-3-phenoxybenzyl-2,2-dimethyl-3- (2,2-dichlorovinyl) cyclopropane carboxylate (cypermethrin) (#)-3-allyl-2-methyl-4-oxo-2-cyclopentenyl (#)-cis, transchrysanthemumonocarboxylate (Allethrin), and the like. In recent years, widespread use of insecticides and miticides has brought about the development of resistance in a variety of vermin. More specifically, the development of resistance to pesticides has been recognized in many kinds of leafhoppers (e.g., Nephotettix apicalis cincticeps), mites and aphides. In addition, the development of resiscance in hygienically noxious insects such as flies (e.g., Musca donestica vicina) and mosquitoes has Become a serious problem because it makes their control more and more difficult. Accordingly, there is a strong demand for insecticidal and miticidal agents which are effect tive against such resistant insects and mites. It is an object of this invention to provide an insecticidal and miticidal composition which can effectively control such insects and mites as are resistant to conventional insecticidal and miticidal agents. In accordance with this invention, an insecticidal and miticidal composition comprises (a) 2-dimethylamino-5,6-dimethylpyimi- din-4-yl dimethylcarbamate (hereinafter referred to as Compound (A); (b) at least one compound selected from the group consisting of organic phosphorus compounds, methylcarbamate compounds, and pyrethroid compounds; and (c) an inert carrier. The present inventors have found that mixtures of Compound A and at least one organic phosphorus compound, methylcarbamate compound, or pyrethroid compound have a very potent synergistic effect in controlling various kinds of ver mjn (such as leafhoppers and mites) which are resistant to conventional insecticidal and miticidal agents. This is quite surprising because Ccmpound A, which has so far been known as an inscticide for aphids, only, is chemically called a pyrimidine carbamate as distinguished from phenylcarbamates and the like and hence considerered to be ineffective against vermin other than aphides. In the composition of this invention, Compound A is preferably present in an amount of form 10 to 90 - by weight, more preferably from 30 to 70 % by weight,. and most preferably 5n 8 by weight, based on the combined weight of all the active in gredients. The composition of this invention may be prepared in the form of a dust, wettable powder, emulsion or granules by mixing Compound A and at least one organic phosphorus compound, methylcarbamate compound, or pyrethroid compound with various wellknown solid or liquid carriers or by dissolving those active ingredients jal suitable solvents. The combined amount of all the active ingredients present in this composition is preferably at least 1 % by weight, and more preferably from 2 to'70 % by weight, based on the total amount of the composition:. More specifically, depending on the form of the composition, the preferred range of the combined amount of all active ingredients varies as follows: Dust...From 2 to 5 % by weight Wettable powder ... From 40 to 70 % by weight Granules ... From 3 to 6 % by weight Emulsion ... rrom 20 to 50 % by weight The composition of this invention is preferably applied to a paddy or upland field in such a way that the active ingredients are deposited in a combined amount of from 1 to 50 g, more preferably from 4 to 30 g, and most preferably from 10 to 16 g, per are of the field. For use in mechanized planting of young rice plants and the like, the composition of this invention is conveniently prepared in the form of granules, though it may be used in the form of an emulsion, wettable powder, or dust. In such a case, the composition of this invention is preferably applied so that the active ingredients are deposited in a combined amount of from 1 to 20 g per are of the field. Specific examples of the insects and mites which can be controlled by the composition of this invention are as follows: Hemiptera Nephotettix apicalis cincticeps llkler Sogatella furcifera Horvath Nilaparvata lugens Stal Laoderphax striatellus Fallon Thysanoptera Thrips oryzae Williams Thrips tabaci Lindeman tnoplura Pediculus humanus Linne Haematopinus eurysternus Nitzah Lepidoptera Chilo suppressalis Walker Spodoptera litura Fabricius Pieris ratae crucivora Boisduval Plutella xylostella Linné Diptera Musca domestica vicina Macquart Culex pipiens pallens Coquillett ColeoDtera Epilachna sparsa orientalis Dieke Callosobruchus chinesis Linné Lema orizae Kuwayama Aulacophora femoralis Motschulsky Hymenoptera Arge pagana Panzer Athalia japonensis Rohwer Orthoptera Locust a migratoria danica Linn Oxya japonica Willemse Phyllodromia germanica Linné Periplaneta japonica Karny Acarina Tetranychus urticae Koch Tetranychus telarius Linné Tetranychus kanzawai Kishida Panonychus ulmi Panonychus citri Boochilus annulatus Thus, the comrosition of this invention permit almost complete destruction of such insects and mites as are resistant to various conventional insecticidal and miticidal agents and hence very hard to control. This invention will be more fully understood by reference to the following examples in which a number of compositions were prepared in accordance with the invention and tested for their insecticidal and miticidal activities. However, these examples are intended .zzerely to illustrate the practice of the invention and are not to be construed to limit the scope of the invention. In these examples, all parts are blt weight and the designations of test compounds are as previously defined. (Preparation of Compositions) Example 1 A mixture of 2.0 parts of Pyridaphenthion, 2.0 parts of rom- pound A. and .96.0 parts of talc was ground to form a dust. Example 2 A mixture of 30.0 parts of Acephate, 20.0 parts of Compound A, Gosenol (a product of Nippon Gosei Kagaku Kogyo Co., Japan), and 48 parts of clay was ground to form a wettable powder. Example 3 A mixture of 2.0 parts of Pyridaphenthion, 1.5 parts of MTMC, 1.5 parts of Compound A, and 95 parts of clay was ground to form a dust. Example 4 An organic solvent solution of 30.0 parts of Pyridaphent:IZon, 20.0 parts of Compound A, and 5 parts of surface-active agents was dispersed in water to form an emulsion. Example 5 A mixture of 3 parts of Pyridaphenthion, 2 parts of Compound A, and 95 parts of bentorite was ground to powder. After the addition of an appropriate amount of waLer, the powder was granulated and then adjusted to an optimum grain size. Example 6 A mixture of 0.5 part of Phenvalerate, 1.5 parts of Compound A, and 98 parts of clay was ground to form a dust. Example 7 A mixture of 2.0 parts of Pyridaphenthion, 2.0 parts of IBP, 2.0 parts of Coumpound A, and 94 parts of clay was ground to form a dust. (Tests for Insecticidal and Miticidal Activities) Example 8 Rice plants were groom in pots until 3 or 4 leaves were put forth and then sprayed with a solution containing each test material at a concentration of 50, 100 or 200 ppm. After air-drying, the rice plants groom in each pot were covered with a cylinder made of wire gauze. Then, 30 organophosphate- and methylcarbamate-resistant male adult leafhoppers (of the Nakagawara strain) which were being successively cultivated (plants of each Dot.) in a laboratory were put onto the rice The pot was allowed to stand for 12 hours-in a room kept at 2500 and then examined for the death rate of the insects. The results thus obtained are shown in Table 1. Table EMI10.1 <tb> <SEP> Death <SEP> Rate <SEP> (%) <tb> Test <SEP> Material <SEP> Conencentration <SEP> of <SEP> Active <SEP> Ingre <SEP> dients <tb> <SEP> 50 <SEP> ppm <SEP> 100 <SEP> ppm <SEP> 200 <SEP> ppm <tb> Single <SEP> Pyridaphenthion <SEP> 0 <SEP> 0 <SEP> 0 <tb> <SEP> Coumpound <SEP> Acephate <SEP> 0 <SEP> 6.7 <SEP> 10.0 <tb> <SEP> Propaphos <SEP> 23.3 <SEP> 56.7 <SEP> 73.3 <tb> <SEP> Phenvalerate <SEP> 56.7 <SEP> 70.0 <SEP> 90.0 <tb> <SEP> IBP <SEP> O <SEP> 0 <SEP> 0 <tb> <SEP> MMTC <SEP> 0 <SEP> 0 <SEP> 0 <tb> <SEP> Compound <SEP> A <SEP> <SEP> 0 <SEP> 0 <SEP> 0 <SEP> <tb> <SEP> Composition <SEP> Pyridaphenthion <SEP> 36.7 <SEP> 96.7 <SEP> 83.3 <tb> <SEP> of <SEP> This <SEP> + <SEP> Compound <SEP> A <SEP> <tb> <SEP> Invention <SEP> Acephate <SEP> A <SEP> .33.3 <SEP> 46.7 <SEP> - <SEP> 73.3 <tb> <SEP> (consisting <SEP> + <SEP> Compound <SEP> A <tb> <SEP> of <SEP> a <SEP> 1:1 <SEP> Propaphos <SEP> 70.0 <SEP> 96.7 <SEP> 100.0 <tb> <SEP> mixture <SEP> of <SEP> + <SEP> Compound <SEP> A <tb> <SEP> two <SEP> ingre- <SEP> Phenvalerate <SEP> 66.7 <SEP> 83.3 <SEP> 100.0 <tb> <SEP> + <SEP> Compound <SEP> A <tb> dients) <tb> <SEP> IPB <SEP> 6.7 <SEP> 20.0. <SEP> 50.0 <tb> <SEP> + <SEP> Compound <SEP> A <tb> <SEP> MTMC <SEP> 6.7 <SEP> 23.3. <SEP> 33.3 <tb> <SEP> + <SEP> Compound <SEP> A <tb> <SEP> Composition <SEP> Pyridaphenthion <SEP> 40.0 <SEP> 73.3 <SEP> 100.0 <tb> <SEP> of <SEP> This <SEP> In- <SEP> +MTMC <tb> <SEP> vention <SEP> + <SEP> Compound <SEP> A <tb> <SEP> (consisting <tb> <SEP> of <SEP> a <SEP> 1:1:1 <SEP> Pyridaphenthion <SEP> 13.3 <SEP> 26.7 <SEP> 60.0 <tb> <SEP> mixture <SEP> of <SEP> +IBP <tb> <SEP> three <SEP> ingre- <SEP> + <SEP> Compound <SEP> A <tb> <SEP> dients) <tb> <SEP> Prior <SEP> Pyridaphenthion <SEP> 0 <SEP> 6.7 <SEP> 23.3 <tb> <SEP> Composition <SEP> +MTMC <tb> <SEP> (consisting <tb> <SEP> of <SEP> a <SEP> 1:1 <SEP> Acephate <SEP> 6.7 <SEP> 6.7 <SEP> 40.0 <tb> <SEP> mixture <SEP> of <SEP> +MTMC <tb> <SEP> two <SEP> ingre <SEP> dients) <tb> Example 9 Each test material was dissolved in acetone to form a solution having a desired concentration. Leafhoppers of the Nakagawara strain were lifatly anesthetized with carbon dioxide and, using a topical applicator, the above solution was topically applied to the thorax of each insect in a dose of 0.32 l. The treated insects were i3nediately put onto young rice plants (with th 2 or 3 leaves) previously grown in a pot and covered with a cylinder made of wire gauze. The pot was allowed to stand for 24 hours in a room ket at 250C and then examined for, the death rate of the insects. (tested in this example) The mixture were prepared in a weight ratio ot 1:1 and their LD-50 values were expressed in terms of the combined amount of to ingredients. The coefficient of synergism was calculated according to the method of Sun and Johnson. The results thus obtained are shown in Table 2. Table 2 EMI12.1 <tb> <SEP> LD-50 <SEP> Coefficient <tb> <SEP> Test <SEP> Material <SEP> ( g/g) <SEP> of <SEP> Synergismê <tb> Phyridaphention <SEP> 225.2 <tb> Acephate <SEP> 30.3 <tb> Propaphos <SEP> 18.4 <tb> Phenvalerate <SEP> 0.32 <tb> IBP <SEP> > 5001) <tb> MTMC <SEP> 123.1 <tb> Compound <SEP> A <SEP> > 5001) <tb> Pyridaphention <SEP> + <SEP> Compound <SEP> A <SEP> 12.8 <SEP> 2411 <tb> Acephate <SEP> + <SEP> Compound <SEP> A <SEP> 17.6 <SEP> 325 <tb> Propaphos <SEP> + <SEP> Compound <SEP> A <SEP> 10.7 <SEP> 332 <tb> Phenvalerate <SEP> + <SEP> Compound <SEP> A <SEP> 0.51 <SEP> 125 <tb> IBP <SEP> t <SEP> Compound <SEP> A <SEP> 3?.5 <SEP> 1333 <tb> MTMC <SEP> + <SEP> Compound <SEP> A <SEP> 79.1 <SEP> 250 <tb> 1) In calculating the coefficient of synergism, the LD-50 values of IBP and Compound A were assumed to be 500 g/g. 2) If the coefficient of synergism is greater than 100, the combination is judged to have a synergistic effect. Example 10 Two compositions of this invention were tested for their miticidal activity against resistant miters. A piece of absorbent cotton was placed in a petri dish of 5 cm diameter and soaked with water. Leaf discs of a kedney bean plant were stamped out by means of a cork borer and placed on the absorbent cotton. Each disc was inoculated with 10 mites and then sprayed uniformly with 1.0 ml of a solution containing each test material. The petri dish was allowed to sand for 24 hours in a room kept at 2500 and then examined for the death rate of the mites by means of a stereoscopic microscope. The results thus obtained are shown in Table 3. The mixtures teste in this example were prepared in a weight ratio of 1:1 and their concentrations were expressed in terms of the combined amount of two ingredients. Table 3 EMI13.1 <tb> <SEP> Death <SEP> Rate <SEP> (%) <tb> Test <SEP> Material <SEP> Concentration <SEP> of <SEP> Active <SEP> Ingredient(s) <SEP> <tb> <SEP> 200 <SEP> ppm <SEP> 400 <SEP> ppm <tb> Dimethoate <SEP> 0.0 <SEP> 20.0 <tb> Pyridaphenthion <SEP> 0.0 <SEP> 30.0 <tb> Compound <SEP> A <SEP> 0.0 <SEP> 0.0 <tb> Dimethoate <SEP> 40.0 <SEP> 95.0 <tb> compound <SEP> A <tb> Pyridaphenthion <SEP> 50.0 <SEP> 100.0 <tb> + <SEP> Compound <SEP> A <tb> Example 11 An emulsion of each test material was diluted with water so a. to give an active ingredient concentration of 5 ppm. A polyethylene cup of 5 cm diameter was charged with 100 ml of the diluted emulsion, in which young rice plants were hydroponically grown so that the active ingredients might be absorbed through their roots. The rice plants were covered with a cylinder made of 100-mesh wire gauze, and 20 resistant male adult leafhoppers (of the Nakagawara strain) were put onto the rice plants After 24 hours, the numbers of living and dead insects were counted to calculate the death rate. In order to examine the durability of the insecticidal activity of each test material, the same procedure was repeated at predetermined intervals of time. The results thus obtained are sho^m in Table 4. The mixtures tested in this example were reared in a weight ratio of 1:1. Table 4 EMI15.1 <tb> <SEP> Concen- <SEP> Death <SEP> Rate <SEP> (%) <SEP> <tb> <SEP> tration <SEP> Number <SEP> of <SEP> Days <SEP> Elapsed <SEP> after <SEP> Treatment <tb> <SEP> of <SEP> Active <tb> Test <SEP> Material <SEP> Ingredient <tb> <SEP> (ppm) <SEP> 0 <SEP> 1 <SEP> 3 <SEP> 7 <SEP> 14 <tb> Propahos <SEP> 5 <SEP> 80 <SEP> 90 <SEP> 70 <SEP> 80 <SEP> 60 <tb> Pyridaphention <SEP> 5 <SEP> 20 <SEP> 40 <SEP> 30 <SEP> 50 <SEP> 20 <tb> Triazophos <SEP> 5 <SEP> 0 <SEP> 20 <SEP> 10 <SEP> 10 <SEP> 0 <tb> Compound <SEP> A <SEP> 5 <SEP> 5 <SEP> 10 <SEP> 0 <SEP> 0 <SEP> 5 <tb> Propahos <SEP> 2.5 <SEP> + <SEP> 2.5 <SEP> 100 <SEP> 100 <SEP> 100 <SEP> 100 <SEP> 100 <tb> + <SEP> Compound <tb> Pyridaphention <SEP> 2.5 <SEP> + <SEP> 2.5 <SEP> 90 <SEP> 100 <SEP> 100 <SEP> 90 <SEP> 95 <tb> + <SEP> Compound <SEP> A <tb> Triazophos <SEP> 2.5 <SEP> + <SEP> 2.5 <SEP> 8C <SEP> 90 <SEP> 100 <SEP> 95 <SEP> 80 <SEP> <tb> + <SEP> Compound <SEP> A <SEP> 95 <SEP> 100 <SEP> 95 <tb> Example 12 According to the conventional procedure, young rice plants (of the Nihonbare strain) were grown in nursery boxes (60 cm x 30 cmx 3 cm). Twenty-one days after seeding (i.e., on the day of transplantation), 50 g of granules containing each test material were applied to one of the nursery boxes and an adequate amount of water was sprinkled by means of a watering can. Three hours after the application of granules a group of 5 rice plants were taken from the nursery box (without removing the soil from their roots) and transplanted to a pot (heavily irrigated so as to be in a paddy-like state) having an area of 1/5000 are The pot was covered with a cylinder made of wire gauze, and 20 resistant male adult leafhoppers (of the Nakagawara strain) were put onto the rice plants. After 24 hours, the numbers of living and dead insects were counted to calculate the death rate. The durability of the insecticidal activity of each test material was examined in the same manner as in Example 11. The results thus obtained are shown in Table 5. The mixtures tested in this example were prepared in a weight ratio of 1:1. Table 5 EMI17.1 <tb> Test <SEP> Material <SEP> tof <SEP> or <SEP> Death <SEP> Rate <SEP> (%) <tb> (concentration <SEP> Granules <SEP> Appl. <SEP> / <SEP> Number <SEP> of <SEP> Days <SEP> Elapsed <SEP> after <tb> in <SEP> % <SEP> by <SEP> weight) <SEP> to <SEP> Each <SEP> Mrrsery <SEP> Transplantation <SEP> ¯¯¯¯¯¯ <tb> <SEP> fl <SEP> (g) <SEP> ¯¯ <SEP> - <SEP> -- <SEP> 8 <SEP> 5 <SEP> 10 <SEP> 15 <tb> vthio <SEP> 's <SEP> 50 <SEP> -| <SEP> 50 <SEP> 7O <SEP> 55 <SEP> 55 <SEP> 40 <tb> dep4nthio <SEP> (5,0) <SEP> <tb> <SEP> 90 <tb> <SEP> Sthglthioaeton <SEP> 50 <SEP> ' <SEP> 80 <SEP> 90 <SEP> 90 <SEP> 7o <SEP> 60 <tb> <SEP> PrqpzFllos <SEP> 50 <SEP> so <SEP> qo <SEP> Ico <SEP> 90 <SEP> 70 <SEP> 1 <tb> <SEP> Propaphos <SEP> 2 <SEP> 50 <SEP> 80 <SEP> 90 <SEP> lCO <SEP> 90 <SEP> 7 <tb> (5"d) <SEP> 1 <SEP> I <SEP> t <tb> Compound <SEP> 4 <SEP> 1 <SEP> 50 <SEP> 10 <SEP> 5 <SEP> 10 <SEP> 15 <SEP> 5 <tb> <SEP> v5y) <SEP> i <tb> <SEP> Pyridaphnthion <SEP> 50 <SEP> 95 <SEP> lOO <SEP> lOO <SEP> 100 <SEP> 90 <tb> <SEP> t <SEP> Compound <SEP> A <tb> <SEP> (2.5 <SEP> + <SEP> 2.5%) <tb> <SEP> Etiiylthioaeton <SEP> 50 <SEP> 100 <SEP> lOO <SEP> lOO <SEP> 95 <SEP> ' <SEP> 90 <tb> <SEP> + <SEP> t <SEP> Com--osind <SEP> A <tb> <SEP> (2.56 <SEP> + <SEP> 2.516) <tb> <SEP> Pronashoo <SEP> 150 <SEP> lOO <SEP> lOO <SEP> : <SEP> lOO <SEP> lOO <SEP> 95 <tb> <SEP> * <SEP> Compound <SEP> A <tb> <SEP> - <SEP> (2.5Yo <SEP> 1; <SEP> 2.5 ;) <tb> (Toxicological Test) Example 13 According to the conventional procedure, young rice plants (of the Nihonbare straing) were grown in nursery boxes (60 cm x 30 cm x 3 cm). Twenty-one days after seeding (i.e., on the day of transplantation), 50 g of granales containing each test material were applied to one of the nursery boxes and an adequate amount of water as sprinkled by means of a watering can. Three hours after the application of granules, a group of 5 rice plants were taken from the nursery box (without removing the soil from their roots) and transplanted to a pot (heavily irrigated so as to be in a paddy-like state) having an area or 1/5000 are. Twenty days after transplantation, the rice plants were examined for the presence of detrimental effects. The results thus obtained are shown in Table fi. The mixtures tested in this example were prepared in a weight ratio of 1:1. Table 6 EMI18.1 <tb> <SEP> Test <SEP> Material <SEP> Amount <SEP> of <tb> <SEP> (concentration <SEP> Granules <SEP> Applied <SEP> Observational <SEP> Date <tb> <SEP> in <SEP> % <SEP> by <SEP> weight) <SEP> to <SEP> Each <SEP> Nursery <tb> <SEP> Box <SEP> (g) <tb> <SEP> Pyridaphenthion <SEP> 50 <SEP> No <SEP> detrimental <tb> <SEP> (5%) <SEP> effect <tb> <SEP> Propaphos <SEP> 50 <SEP> Appearence <SEP> of <SEP> brown <SEP> spots <tb> (5%) <SEP> in <SEP> leaf <SEP> tips, <SEP> followed <SEP> by <tb> <SEP> recovery <tb> <SEP> Compound <SEP> A <SEP> 50 <SEP> No <SEP> detrimental <tb> <SEP> (5%) <SEP> 50 <SEP> effects <tb> <SEP> BPNC1) <SEP> 50 <SEP> Withering <tb> <SEP> (5%) <tb> MTMC2) <SEP> 50 <SEP> Withering <tb> <SEP> (5%) <tb> <SEP> Pyridaphenthion <SEP> 50 <SEP> No <SEP> detrimental <tb> <SEP> + <SEP> Compound <SEP> A <SEP> effects <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> <SEP> Propaphos <SEP> 50 <SEP> No <SEP> detrimental <tb> <SEP> + <SEP> Compound <SEP> A <SEP> effects <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> <SEP> Pyridaphenthion <SEP> 50 <SEP> Withering <tb> <SEP> + <SEP> BPMC <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> <SEP> Propahos <SEP> 50 <SEP> Withering <tb> <SEP> + <SEP> BPMC <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> <SEP> Pyridaphenthion <SEP> 1 <SEP> 50 <SEP> Withering <SEP> <tb> <SEP> + <SEP> MTNC <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> <SEP> Propaphos <SEP> 50 <SEP> Withering <tb> <SEP> + <SEP> MTMC <tb> <SEP> (2.5% <SEP> + <SEP> 2.5%) <tb> 1) o-sec-Butylphenyl methylcarbamate 2) m-Tolyl methylcarbamate

Claims: What is claimed is: 1. An insecticidal and miticidal composition comprising (a) 2-dimethylamino-5 , 6-dimethylpyrimidin-4-yl dimethyl2rbamate (b) at least one compound selected from the group consisting of organic phosphorus compounds, methylcarbamate compounds, and pyrethroid compounds; and (c) an inert carrier. 2. The composition according to claim 1 wherein the active ingredient (a) is present in an amount of from 10 to 90 % by weight based on the combined amount of the active ingredients (a) and (b). 3. The compositions according to claim 2 wherein the active ingredient (a) is present in an amount of from 30 to 70 % by weight based on the combined amount of the active ingredients (a) and (b). 4. The composition according to claim 1 wherein the combined amount of the active ingredients (a) and (b) ist at least 1 % by weight based on the total amount of the compovition. 5.The composition according to claim 4 wherein the combined amount of the active ingredients (a) and (b) is from 2 to 70 % by weight based on the total amount of the composition. 6. The composition according to claim 1 wherein the active ingredient (b) is diethyl 2,3-dihydro-3-oxo-2-phenyl-6-pyridazinyl phosphorothioate, O,S-dimethyl N-acetylphosphoroamidothioate, dipropyl ±-methylthiophenyl phosphate, 1-phenyl-1,2,4triazol-3-yl O,O-diethyl thionophosphate, diethyl S-(2-ethy- thioethyl) phosphorothiolthioate, S-benzyl diisopropyl phosphorothiolate or 2-diet'.ylamino-6-methylpyrimidin-4-yl-dimethyl phosphorothioate. 7. The composition according to claim 1 wherein the active ingredient (b) is m-tolyl methylcarbamate. 8. The composition according to claim 1 wherein the active ingredient (b) is &alpha;-cyano-3-phenoxybenzyl-&alpha;-isopropyl-p-chloro- phenylacetate,&alpha;-cyano-a-phenoxybenzyl-2,2-dimethyl-3-(2,2-di- chlorovinyl) cyclopropane carboxylate. 9. The composition according to claim 1 wherein the active ingredient (b) ts a combination of diethyl 2,3-dihydro-3-oxo-2phenyl-6-pyridazinyl phosphorothioateand:m-tolyl methylcarbamate or S-benzyl. diisopropyl phosphorothiolate. 10.A method of controlling insects and mites which comprises applying the composition according to claim 1 to a paddy or upland field in such a way that the active ingredients (a) and (b) are deposited in a combined amount of from 1 to 50 g per are of the field.

Inventors: IMAI, TAKAMITSU, TAKASAWA, YOSHIO, TOYAMA, TERUHIKO, UDAGAWA, TAKATOSHI
Applicants: IMPERIAL CHEMICAL INDUSTRIES PLC
Application year: 1980
Main classification: A01N57
IPC codes: A01N53, A01N57, A01N47