Really cozy quiet house, great host, walking distance of the awesome Portland public transit (9, 17, 19 buses + A, B, NS, and Orange line trams). You can even walk downtown along the waterfront or cross over to the East side using Tilikum bridge if you're into walking/biking/running.
Didn't have any issues with the highway noise (in fact didn't hear it at all except when you're outside). Would definitely recommend!