The location is killer; you really can't beat it. Walking distance to cute and quirky shopping, lots of dining, and lots of cool bars. I felt very safe in the area and in the house. Parking is a liiiittle tricky as it's a popular area, but it's nice that they provide the parking passes so you don't have to pay, at least.
The little heaters in the house are powerful and get it nice and toasty, fast! So that Portland chill won't get to ya. Clean and comfortable space with everything you need (though only a microwave and toaster oven, no stove/oven if that bothers you. Was fine for us). Lots of natural light.
You can hear the residents in the house above walking around sometimes, but with so much to do in this neighborhood, I'd just recommend spending time outside instead! Never was anything major, and never bothered my sleep. Overall, a great place to stay for a Portland visit!