This house is really spacious (5 rooms and plenty of open areas - plus the terrace with a pool!) and it's comfortable! It might look far from the Cathedral, but it's reasonably close, and the walk takes you through the heart of Seville, with its cafés and shops and it's a worthwhile experience. It's also a 1 minute walk to a square with cafés and restaurants, and a DIA supermarket, where you will find everything you might need during your stay.
Other reviewers have noted that the house has a smell; this is true but it was very faint during our stay and not bothersome. Previous guests also remarked on the area being a bit "scary." The surrounding streets are quite narrow, so cars don't tend to drive on them and that makes for a quieter neighborhood. We never felt threatened or unsafe, rather the opposite, with families walking around and visiting nearby shops, day or night. However, these streets are also used by residents to walk their pets "etc.", and thus do appear dirty. You will unfortunately find this in other areas of Seville as well.