A bit far from Santa Justa train station. But near the Alsa bus station. Minutes away from Alameda.
Get a good map which shows the smaller esquinitas but you’ll be fine with google map (we didn’t have mobile wifi so relied on maps).
You won’t starve as in every corner there are restaurants. Casa Paco in Alameda square: good tapas at good prices (right next to Hotel Sacristii de Sta. Ana).
The property is very ideal if you want to visit during the Semana Santa as the processions pass by on or near the property.