Pepe's and Manu's apartment is very cosy and provides everything you'll need for a nice stay. Even though it's literally in the heart of Seville and in a vivid area, it's a very quiet place so you can perfectly rest after a day in the city. All main sights are at walking distance and Plaza Nueva is just around the very next corner.
We came by train and plane and reaching the apartment with public transport is no problem at all.
All in all: a very good option when going to Seville!