Manuel's flat is highly recommended.
It is very near the "Setas" where you will find a taxi stop that is very handy for the airport. Alfonso XIII hotel, the Encarnación, the Campana, Catedral, Alcazar, Alameda and Macarena Arch are examples of walkable places you can visit from this flat location. In the entrance of the building you have a good tapas place so you don't need to go very far away to have nice tapas.
Inside, it is as you can see on photos. We did love the decoration and the quality of the shower and bed! that no in every place are good.
Very nice place to stay if you are thinking in enjoy Seville for few days.
We would be happy to stay there again.