The place is situated in a most central place. You can walk to all the important sightseeing spots as well as to shops, stores, bars, restaurants, gym, public transportation. Cabs just in front of the house. Although it's central location you will not hear any street noise at all. The neighbours were quite loud some nights, but Isabel took care of it by talking to them. She was concerned about my well being and easy to get in touch with when I needed something. The apartment is great for a stay in Sevilla, beside the unbeatable location it is well equipped, very modern and cosy, you'll feel at home instantly. The only tiny downside to mention is the fact that you get hardly any daylight since it is an interior apartment. But that is not too much of a problem unless you'd use the apartment for a working place and planned to stay inside a lot (which I didn't).
I recommend it very much!