The house was phenomenal, easily fit our group, and is not too far from 6th Street and downtown (about 15-minute drive). Be willing to walk around some by the house, we found a great Mexican restaurant in walking distance (less than 5 minutes) and if your will to walk about 20 minutes there are two breweries nearby.
Both George and Lisa were responsive to questions we had and were very helpful in allowing us to check out a little later because our flights were late afternoon.
I'd definitely recommend this place for your Austin trip!