As a former New Yorker, I'm familiar with this general area.
This is a great location to stage an attack on Soho, Noho, Nolita, east village, China town. Less so the west village, but doable for eager walkers.

The place is a perfect. Clean and decorated. amazing roomy arrangement considering the space and the patio is better than it appears in the pictures.

I never got to meet Esef- but he communicated great over email and made all arrangements as promised. Will absolutely consider returning here for my annual visits.