If you want to be centrally located in manhattan - If you want to stay with people who are truly interested in you having a fulfilling and low stress vacation - you really should consider Art and Ed's place in the heart of Chelsea. It is right on the Chelsea HighLine, which is a terrific addition to a city that doesn't even need more reasons to visit! Art and Ed could not have been more helpful to us. It is like having a concierge in-house. If we had a question, we had a human version of Google to check in with! Also - if cleanliness is important to you - this location will make you so happy! It also feels great to not worry about your personal belongings as you do in hotels. If you have not tried this sort of housing in NYC, Art and Ed's place is a perfect start.