This was our second visit to the Box House, and I don't think we would chose to stay anywhere else in New York from now on. With our own spacious high ceiling apartment, we could prepare and eat our own breakfast - and one evening dinner. North Greenpoint has character and charm that Manhattan doesn't, some great local restaurants (check out the fantastic newly opened Glasserie, just round the corner, or the hugely popular Five Leaves). Don't be put off by the location in an industrial/Polish area, it feels authentic, and the hotel driver will deliver you (or pick you up from) anywhere in the locality in their own taxi.
Beds are extremely comfortable, and furniture more than adequate. Decor is modern/funky. Service at the desk is helpful and friendly. The place has a homely feel - its not large or impersonal.
Access to Manhattan is easy - 2 stops on the 7 from Vernon/Jackson (a 15 minute scenic walk across the Pulaski bridge or a drop from the driver) gets you to Grand Central.