Great location for visiting different locations in Manhattan, closeness to Lines 6 and 2,3 is simply time saver to get different places in relative short time.
Please be aware this place is located on a third floor without elevator, not a problem is traveling light, however larger baggage might be difficult to handle.
Definitely worth to consider this listing if you are traveling on a budget the tradeoff is: neighborhood is a bit noisy and building a bit old and dusty.