This place is quiet, comfortable, clean and stylish. Ruby and Danny have made check-in a breeze and were very responsive throughout my stay. It's in a great location if you enjoy 5-15 minute walks to great restaurants, coffee shops, bars, breweries, bakeries, and delis. It's a noticeably Hasidic Jewish neighborhood, which was interesting for me to walk through. Ruby mentioned that I may hear some alarms denoting the beginning and end of the Sabbat on Friday, but I never actually noticed.
I went into Times Square and lower Manhattan a few times and found the public transportation to be very convenient (~half hour). Getting to and from JFK took a little while (~1.25 hours), but was cheap and convenient as well via the air train and Metro. I had a chance to walk with Ruby and her son as they were headed to the M train to get him to school. They're both really friendly and fun to talk to.
I'd highly recommend staying at their place if you're in NYC.