Yasu and Akiko's place was perfect. It is located on a street full of great restaurants and bars, so there is never a dull moment. That being said, it can be a little loud at night. But its centrality and size make it worth it. Be warned: there are a lot of steps to get up to your room, and the staircases are quite narrow. As long as you aren't lugging a lot of luggage, it should be fine.
The room was large for NY standards, and having a private bathroom was a plus. Although their are a lot of other guests in the house, the room feels absolutely safe - each room has its own lock that can only be opened with a code provided right before your stay.
Overall, I enjoyed my stay and will definitely be back.