There's location, and then there's LOCATION!! On three separate days we walked to the Hi-Line, Central Park and Times square without any hesitation. Easy walk to subway stations taking you anywhere. And if you wanted to see a show - have to be 15-20 theatres within 3 blocks.
Restaurants of all the foods of the world dot every other doorway and there's a Duane Reade (Walgreens) or grocery type market on every other corner to stock up on some minor supplies.
The location easily slept the four of us and while yes, it's New York and there are night sounds, the AC unit did double duty keeping us nice and cool during a particular hot night and drowning out most of the outdoor noise. Great place for a multi-day visit.