Philip's house worked really well for us. It has a nice layout and great subway access to whisk you into Manhattan. We used the Citymapper app and google maps, which were really helpful for finding our way around the subway system.
The location is fantastic, in addition to the subway stop right across the street, the neighborhood is full of great looking restaurants that, unfortunately we didn't have enough time to try. We've got that on the list for next time. There is also a great, reasonably priced Union Market just a couple blocks away.