Centrally located - right next to subway, 10-15min to Times Square despite being across the water. Very close to subway actually - noise could be an issue for some very sensitive types, but it was fairly muted and you should always travel with earpugs no matter what.
Radiator (I think it was that) kept banging in the night, common problem with old pipes and radiators.
It's an old townhouse, very comfortable, but not the best for young children. Common area and bathroom shared with multiple guests, each of whom have private, locked rooms, no issues there.