I'm favorably biased because I used to live 3 blocks away. Not central in a midtown Manhattan kind of way. But one block east and you're on Broadway with a variety of eats and buses to midtown. A couple blocks more to the #1 train and 10 minute ride to midtown. One block west is chiller Riverside Park with the Hudson below. Gracious, welcoming and flexible host. All the basic amenities. The ladder to the loft bed means you'll need to be reasonably limber (see photos).