We had a great time staying at this AirBnB and exploring Asheville. The place has everything you need for cooking, sleeping, washer / dryer etc and the location is walking distance to many breweries and restaurants.
As others have mentioned there is a homeless shelter across the street, however, it is closed on the weekends and is only really busy in the mornings when they serve breakfast. We had no issues at all during our stay and felt completely safe.
We would definitely stay again the next time we are in town!