We didn't even realize how important some r&r would be this weekend when we booked it, but dang, I'm so glad we did. Wander Trees is a cute, cozy, comfortable urban getaway on the main drag with great proximity to all of the things we wanted to do while in Asheville: less than two miles from almost everything we GPS'd, I swear it. There are stairs, but I'm a lower limb amputee with a prosthesis and I did just fine. We had a great time in Asheville this weekend and it was a real nice spot to come back to after a day of exploration and a night on the town (seeing Guided By Voices in a tiny club on a chilly weekend was pretty great, having a comfortable warm bed after was also pretty great.)
Non-traditional travelers, if you're not really into the Biltmore tourism scene, this end of town is where you want to be, and this is a good place to stay.