This place is all about location- it's insane how well positioned this place is in the North End. After the location, the second best thing is the comfortable bed.
Like any old building, you should expect to be able to hear your neighbors from time time. This wasn't a major issue during my stay, but if you require complete quiet, you may want a more traditional hotel. This felt similar to European Airbnb's I've stayed in.
Beware that the food in the immediate vicinity will cause you to put on weight because it's so good.