Byron's place is a great option if you want to be close to the French Quarter, but not right in it. However, be vigilant. My friend and I decided we would be ok walking to and from the home at night, as we are from a big city and feel comfortable doing so. But while walking back from Frenchman Street on our last night, we were robbed. It could have happened anywhere, but if you choose to stay in the area I would recommend taking Uber and Lyft late at night.