Irish Channel is a little off the beaten path, but is a nice quiet neighborhood. It's a quick walk to good bars and restaurants on Magazine. I highly recommend getting to know the bus route along Magazine (it's fun), but also it's a very resonable fare by Lyft anywhere you'd want to go. I also recommend joining Blue Bike ($15 unlimited use for the month; still a great deal if you only are staying a few days). The best place for breakfast (every day) is the Ruby Slipper on Magazine (there's not much else open early - I like to eat by 7 or 8). They serve French Truck coffee (or, keep going on Magazine towards downtown, and go to the French Truck on Magazine - highly recommended).