My family stayed at Leda and Don's home for the holidays and we had a great time. Their house is quite lovely and spacious, with two bedrooms downstairs and two bedrooms upstairs. Note the there is only one bathroom - but even in our group of 5 adults, it didn't pose any inconvenience. The kitchen is stocked with dining and cooking wear, as well as some spices and oils, etc. It is located conveniently close to the French Quarter. The neighborhood is what we call "transitional" in NYC - an abandoned house was visited by the police, while renovations take place on a lovely home next door, for example. I wouldn't let this be a deterrent, however. Just an FYI. We felt safe, regardless of time of day.
I happily recommend Leda and Don's home for your stay! It's perfect for families or groups of friends who want to be within walking distance of the Quarter and/or Bywater, but in a quiet neighborhood.