I booked Isaac's place on Galvez for my friend's bachelor party, a 3-day weekend checking in on Friday and out on Monday, and I couldn't be more satisfied with the stay. You'd think that when trying to accommodate 17 guys, some things would fall through the crack, but this spot had everything we needed to spend our down-time in comfort.
Almost every sleeping location in the two side-by-side units is a full-size bed besides a couple couches, but Isaac includes blow-up mattresses as well, so no one even has to sleep on a couch if they don't want too. Each unit has a full kitchen, two bathrooms and access to a shared backyard. Isaac provides additional furniture so that the entire group can hang out in the same spot and all the basics you'd need (towels, garbage bags, etc.).
In terms of location, we took Lyfts and Ubers almost everywhere we went, but they never turned out to be more than around $13 -- which means splitting them made transportation to and from the place almost a non-factor. The address is right in the middle of where you want to be, about a mile from the French Quarter, but also near the highway if you're looking to go explore the greater surrounding area like we did. There's also a gas station and Whole Foods in very close proximity.
And as a host, Isaac was always incredibly helpful, responsive and accommodating. If we ever needed something or some information about the place, I was able to reach him through the Airbnb app in less than 10 minutes. Isaac was also totally understanding of the large group / bachelor party atmosphere and aimed to be as helpful as he could in that regard as well.
Basically, if you're looking for an awesome time in New Orleans with a large group of people, this is the place you want to be.