We saw Gwens place while trying to find an affordable airbnb here in NOLA. While this place was affordable, it is not in the safest part of town. I traveled with a female friend and we were occasionally uncomfortable with the area and accessibility of the room.
There is a charm to the quirk of Gwens place but keep in mind that it may not be as clean or accommodating as you might expect. Gwen herself was very kind and the place definitely gave us a story to take home. I would tentatively recommend as long as you are comfortable with what you are signing up for!