We had a wonderful long-weekend stay at the Josephine! The location was amazing, so close to the French Quarter and Business District. There are a few restaurants, coffee shops, and bars located steps away from the front door. It is about a 10 minute walk from Jackson Square, making it easy to walk back after a night on Bourbon Street. We felt incredibly safe in this area. I had no issues during the stay, the hosts were incredibly responsive and it was everything I would expect from the listing.
That being said, there are two flights of steep stairs that need to be climbed to get to the unit. It was fine for a girl's weekend, but you may want to be aware of that if you are traveling with young children or anyone that has issues with climbing stairs. Being that this location is smack dab in the middle of New Orleans, don't expect a quiet and peaceful night. Sounds of people on the street and traffic travel through the walls pretty clearly all through the night. It's something I expected staying in the city, but consider it if that's something that may really bother you.