The guesthouse was exactly as described and pictured. Rita allowed me to check-in a couple hours earlier than 4pm, though I never met Rita (though I didn't try and seek her out). Never felt nervous in the neighborhood coming and going to Frenchman street and the quarter.
The upstairs area was absolutely wonderful with its awesome windows that allow plenty of natural light in. Bed was comfortable and nice to lay in after a day of walking around. The spiral stairs did require a tiny bit of extra work in getting my luggage up, but I wouldn't really count that against the place. There was a several occasions that you could hear train whistles in the wee hours of the morning, but they didn't really bother me.
All in all, a great listing and the first place I'd look at if I return to New Orleans.