My friend and I were in town for Mardi Gras - not only was Brenna and Nick's the perfect place to stay for this, but it was also a prime location when you're trying to explore New Orleans in general.
Because we stayed during Mardi Gras weekend, the parades that moved through Uptown were pretty much a few steps out on the next cross street (this also gave us some quiet and privacy needed whenever we needed to walk back home). Mardi Gras aside, this was a prime location, because we were close to the streetcar and bus stops (easy access to public transportation to the French Quarter). We were also close to good restaurants/cafes around Magazine St & St Charles. The neighborhood was safe and quiet.
The place itself was clean, cozy, and comfortable. Everything looked exactly like the pictures. A comfy bed, clean bathroom, closet, and some extra storage space - just what we needed for a few days' stay in NOLA. I'd definitely recommend.