I recently stayed a Wrigley Hostel for two nights while stopping in Chicago for a couple days, while on a train journey around the country.
It is definitely a great spot to stay if you are looking for a safe space that is also in a lively area of the city.
The hostel was clean, quiet, stocked with all the essentials that you may need, and seemed like it would cultivate a nice sense of community if you were looking to stay a bit longer.
Best of all, though, would be the people who work there. They were very kind, communicative, and helped to make my stay a very pleasant one.