I had the opportunity to stay at the Blues Brothers Express in the South Loop while attending the conference. It is conveniently located near an L train stop which provides fast and cheap transport from both O'Hare (my port of entry) and Midway airports. The location was also a short walk from multiple groceries (Trader Joes and Jewel Oscos), drug stores (Walgreens), and many great restaurants and bars (may I recommend Flo & Santos next door, Lou Malnatis deep dish, and Yolk breakfast spot around the corner), some that Charlie pointed out and others I discovered while walking around. It is also a short walk from many famous attractions, including Soldier Field, the aquarium, Cloud Gate Park (the "Bean" is there), and attractions near the river (check out the boat architecture tour!).
The bed (futon) was actually very comfortable and there plenty of extra blankets available in the closet in case you get too cold at night (there is also a heater, though I did not test the AC during my winter trip).
Amenities included a fridge/freezer for any groceries or leftovers, stove and oven, mini keurig (with lots of extra K-cups from prior visitors), and some miscellaneous food items, dinnerware, and cutlery available.
Just a heads up that the L train runs right outside the window and can be a little loud at times. I did not find it too problematic as I normally sleep with earplugs and the train does not run as often at night. I slept through the night during my stay. The bathroom was also a bit on the small side and although I am a bigger guy, I still fit.
Charlie was quick to respond to my questions and the check-in/out process was simple and straight forward. I definitely enjoyed my time while staying here.