Janet's place is a wonderful neighborhood place to anchor near Lincoln Square. It's a spacious suite that is thoughtfully decorated and modern. A few breakfast staples, snacks and a nice bottle of wine await, all of which you may enjoy in the lovely backyard patio and garden just steps from your door. Janet & Chuck are very responsive and offered some specific suggestions on what I might enjoy doing during my visit, and they very graciously agreed to accept a letter on my behalf, which I will need during my travels.
Lincoln Square is a pleasant neighborhood avenue and offers a number of shops and restaurants for browsing and a meal -- breakfast, lunch and dinner. I was not disappointed in any of my restaurant choices. In particular, I enjoyed a dinner at Bistro Compagne one evening, where I sat in the lovely garden. If you visit in Summer and the timing is right, check out Gene's Rooftop beer and wine garden on the weekend, but either way check out Gene's Sausage Shop and Delicatessen to see the wide variety of imported European foods.
If you drive, you can park on the street thanks to parking stickers Janet & Chuck will provide, but public transit is very accessible. I walked a lot, but I also rode the L (nearby Brown line station at Western in Lincoln Square or at Damen), the bus, and rented a Divvy bike, which are ubiquitous in the city.
You can go anywhere in Chicago from here, but I was happy during this AirBnB stay to spend more time exploring nearby neighborhoods and getting a feel for what it would be like to live here.