Vita nicely exemplifies the spirit of Airbnb. She and her family were very hospitable, incredibly helpful, and pleasant to hang out with. There is not one thing I asked them to help me with and didn't get what I needed. At the same time, everyone was very discreet and privacy was never an issue. The house is big and has everything you'll (normally) need. The only problem with the room is that, because it's right in the center of the house, things can get a bit loud or busy sometimes. But I generally didn't mind and I'm sure Vita would be more than happy to accommodate your needs.
The house may not in the best part of the city, but I never felt unsafe, the neighbors are friendly and helpful, and connections to downtown are good (by DC standards, which means bad in every other major city).
I'll pay Vita a visit next time I'm in DC and you should too.