Very close to Union Station.
Can walk to Museums if you don't mind the humidity and it's about 3-5km depending on where you want to go.
Bike hire (cheap and convenient) literally the next street and there are bike stations all over the place - and quite flat so it's not too strenuous.
Good restaurants very close by, and there are a couple of markets if you wan to prepare simple stuff in the BnB.
Perfect place for me - 3 nights and couldn't have been happier.