The location is great. The neighborhood has a lot of good restaurants, bars, and some breweries which are all easily accessible on foot. We were able to walk into downtown Denver as well (about a 15 minute walk but there's also a free shuttle when you cross over the river). Even though you're close to downtown, the bedroom was still very quiet at night.
The space for the guests is right at the entrance and is separate from the living room/kitchen and the other bedroom. This was nice because we felt that we had our own little space to come back to after exploring.