My girlfriend and I arrived late at the house, but it wasn't a big deal for Irene.
She showed us our room with private bathroom, awesome by the way, and gave us a lot of brochures and good tips on what to do the next days.
The last day she even allowed us to leave the luggage in the house so we could go around the city free of them till the late afternoon, time of our fly.
The house is really beautiful, up to a hill, with an amazing view from the living room. I don't know how easy is to reach the house without a car though, we had one and we used it especially to go to Daly city station to take the Bart to the city.
Irene is a really nice host, always available and ready to chat with her guests.
Highly recommended