During a business trip to SF, me and my colleague stayed in Jason's apartment. It was a great option for our trip, well catered for this situation: two equal bedrooms, clothing rack, enough kitchen supplies for breakfast and shops around the corner. The Bart is accesible by bus or a 15 min walk, which brings you downtown SF in 15-20 min. We had lots of meetings in the South Bay, which was in easy reach with a rental car.