This downtown location is outstanding! Everything you need is walkable. I decided not to rent a car and I rarely needed an Uber. Walk to gaslamp, Balboa Park, Little Italy. Very short Uber/Lyft to Old Town, Pacific Beach, Ocean Beach, Coronado Island and the airport. Even getting to Tijuana was simple and fast via Uber or light rail.
Location is most important to me, but the apartment itself is also perfect. I was concerned about reviews regarding the bed, but it felt great to me and I slept well each night. Temperature was always comfortable with the AC unit. Also huge perk is the option to store luggage a couple hours before or after checkin/checkout in secure closet.
Tip: get morning coffee across the street at Achilles and enjoy it in the apartment garden out back. I watched hummingbirds drink in the birdbath.