Excellent location, close to airport, downtown, Gaslamp, Seaport Village, and Balboa Park. Very cheap Uber rides ($5-$6) to these places. There is also a bus stop right around the corner of the house.
The place itself was exactly as pictured. Cozy and nicely decorated. Comfortable bed in a quiet home. There is noise from outside due to highway nearby.
Overall, it was an enjoyable stay at Mario and David's. Location is definitely the #1 advantage of this place.