This is about as central as you can get in San Diego. Great, vibrant neighborhood and very stylish but comfortable place. We got to and from the airport and the harbor Sheraton in less than 10 minutes many times, and I even rode a rental bike a few times on that route during our stay. We also could jet out (via rideshare apps) to Balboa Park, Old Town San Diego, the multiplex at the mall, and other sites/sights in a breeze.