If you're outside, then yes, you will hear the planes flying directly above as they make their descent into San Diego airport. However when you're inside, you won't notice it. At least the 4 of us that stayed there for 4 nights didn't! We do slept just fine and we're all from the burbs.
It's a great location.. walking distance to a pretty good New York style pizza joint named Luigi's. Taking a Lyft in and out was super easy too (and we were here during Comic Con 2019).
Janna was super communicative from booking to checkout.