This place is in an excellent location.
Our grouped walked to Little Italy a couple of times and even though it was uphill on the way back, we did walk back twice. Its location also makes your Uber charges minimal for city sites and the zoo.
We were a group of 6 and were comfortable staying here for 5 nights. The kitchen area is small but does has pretty much everything you need. We were able to cook breakfast for our group each day. We used the dining table for our evening area, playing card games and such since the sitting area (couches) are located in the front bedroom which was in use.
There are a couple of smaller grocery/liquor stores close by and some really good restaurant choices within walking distance or a short Uber.
If we return to San Diego, we would definitely consider staying here again.