Airbnb is super central and kid friendly. We had a 2 year old and there were a lot of toys and kid bowls/ utensils. The Airbnb is also about 15 mins away from most things so renting a car or Uber/Lyft prices are reasonable.
One thing — we had 6 adults and 1 two-year old and found the Airbnb a little small for our group. Also, a little outdated.
Otherwise, we really enjoyed our stay and Emily was very helpful and accommodating with any issues or questions we had about San Diego.