I live in San Diego and stayed in this rental for a week while my own house was unavailable. I was able to walk to work near the train station (edge of Little Italy) morning and night very easily. Here's the real value of this place:
1) If you want/need to stay downtown, lil' Italy or Balboa Park, you get a fully functioning room/studio for probably $90 less/night than a comparable hotel. If you are staying for many nights, this is huge savings.
2) The location is great for downtown (gaslamp, east village, padres) as well as Balboa Park, Hillcrest, Little Italy. Frankly, if you are looking to stay in this neighborhood, you probably want to be out *in* these neighborhoods, and IMO overspending on a hotel would be a mistake. You can hop on a rideshare scooter or e-bike and be to any of the "downtown" attractions in minutes.
(Re parking - My advice would be to drop off you bags, go park a mile or two a way, and then rideshare-scoot back to the room.)
This isn't necessarily the solution if you want a fancy/ostentatious downtown location for a big date night or a place with a great view for the 'gram- but that's an entirely different class of visit and not a fair comparison/competitor.
Very easy to get in/out. Host is a great communicator, and very accommodating - but I didn't need to ask for a thing.