I really enjoyed my stay at Casa Mayra, here are some pros and cons.
Pros: perfect location, very walkable. Close to Amtrak train station and easy drive to airport. Location was also safe and well populated even at night. Great food nearby. Bed was comfortable, everything was clean. It was only noisy if the air conditioning unit was turned off, which I had no problem with because I kept it on. If you bring your own car they have a parking pass included. The hosts are very easy to communicate with. They also let me check in an hour early which was a great help.
Cons: The smell of marijuana was extreme some nights. It was not a HUGE deal if I closed the bathroom door however it did smell significantly in the bathroom because of the window in there. No elevator and very steep staircase. No deadbolt on the door which is really a personal safety preference as a solo female traveler. The door does have a lock! Just not a deadbolt.
Overall I enjoyed my stay and would stay again if in San Diego, but I would probably pack lighter because of carrying my suitcase up the stairs! :)