We loved our stay at Marie and Charles's place! We already love Ocean Beach so I would tell anyone looking for a laidback visit to the San Diego area to check this neighborhood out. The place is very close to the beach and main shopping/dining area of Ocean Beach. Technically it is walking distance but with two children, we just drove the five minutes to the main strip and always found parking (which is free up to two hours) no problem. We love breweries and there are several (Belching Beaver, Culture, Mike Hess, Kilowatt, and others) located within walking distance of each other. The beach is very relaxed and not too busy.
As far as the guest house itself, it is the perfect size for a couple or a small family. It definitely started to feel a little cramped if we stayed for too long but since we spent most of our time exploring, it was a perfect cozy spot to come back to. My favorite spot was the balcony. It is so spacious and has comfy furniture where you can just relax after spending the day at the beach.