This is a really convenient location, as it was never more than 15 minutes away at most fromost of the hit spots in San Diego. For Downtown destinations and the airport, it's only 10 minutes away, and even less than that for the Zoo.
It should be noted that there is no AC. There are several fans, but folks who need AC should keep this in mind. The planes can also be heard as they descend and there's a nearby bar, but the noises from there were surprisingly easy enough to ignore after a little bit.
Overall, very convenient spot to put your head down as you focus on exploring the city. Beth is very communicative and kind, and having her for a host was great!