Kewl, fun themed room. Located in a good spot between Gaslamp and Little Italy, and within reach of Balboa Park too. We did lots of walking. Eventually rented a car to see the sights outside of the downtown area (Coronado, Ocean Beach, Mission Beach, La Jolla, etc.). Expect to pay $$ for parking in downtown area, although the metered parking is free between 6p-8a near the room if you can find one. We parked at Park-it-on-Market for $15 night (vs $30-$35) just so I didn't have to pay for the meter at 8a (which was only by the single hour-so kind of inconvenient to go back each hour).
We spent 7 days in the room, which was probably a little too long for such a small room, but we made it work. Half that time would have been a better target.
Homeless and street people are more commonly seen in the Gaslamp area vs. Little Italy, but they all seem to keep to themselves and there was never a feeling of being at risk while walking around, even late into the night. I also saw a greater number of private security folks stationed around the area. The main entrance into the building is entered with a code, so that extra security is nice too.
Overall we had a great time experiencing the downtown areas with all the other tourists. Friday and Saturday nights were hopin' with the local party scene, and it was a fun part of the festival atmosphere which is the Gaslamp.
We definitely recommend a stay to experience the Gaslamp/Little Italy neighborhoods, and this room and location are in a great spot to do it!