We stayed at this house for a family trip to San Diego from Texas with five kids 10 and under, and five adults. The rooming situation worked out well for us, though the big upstairs room doesn't have blackouts on the doors if you're trying to find a dark place for a baby or toddler. The beds were all super comfy and the house was very clean and organized / labelled with where we could find all the basics - saves time in a new house for sure! The location was really great for us as it was a very easy drive to the zoo and Balboa park, plus Little Italy and La Jolla which was all on our list! I'd definitely recommend stopping at the Windmill Farms grocery store for a sandwich and grocery essentials - super close and really yummy food.
We did have a nice stay, but I'm not sure we would stay again with small children. The back of the property kind of drops off after a little fence and we were constantly concerned a kid was going to climb the fence or slip through the bars and roll down the sharp drop off. Also, the pool is right outside the door, and there are probably 5 doors to the outside which had the adults constantly watching to make sure our 2 year old didn't take a dive in the pool.
We didn't have any issues with neighbors or anything huge wrong with the house. The one thing I'd mention is that if you are sensitive to fragrance, to know that there's quite a bit of it in this house. I suggested a change to the hosts, but it's something that affects me when I travel so I always want to know about it ahead of time!
The hosts were very responsive to needs during our stay and even had baking sheets delivered next day so we could make cookies for my MIL. All in all, I would recommend this house to someone else, especially if you have a group with older kids or all adults.