Nathan's place is east of downtown San Diego. If you use public transportation to get around, I would highly recommend using the nearby 12 bus, about a 30 minute ride into downtown. The Orange line does make a stop about a 15 minute walk away but there are a couple of hills to climb along the way. There's no air conditioning in the room but if you leave the window open during the day, the room will be comfortable when you return at night. You will be a guest in a family home but if you're laid back and respectful, this is a great place for the value. I would definitely stay here again.