What. A. Find. For a few dollars less and in the same area, you can sleep on other people's sofas and share a bathroom with them. This place gives you the privacy and comfort of your very own studio apartment with your own bathroom, closet (with hangers!), coffee maker, microwave, and mini fridge. The decor is great, quirky but tasteful. It's also clean, no dust bunnies, no grunge. And Bill is very responsive!
The location is wonderful. The street is relatively quiet for downtown San Diego (you will still have some street noise, but it's not outrageous), but you're about a 10-20 minute walk from everything: the harbor, the zoo, the Gaslamp district. The food offerings within a 2-3 minute walk are also great (I recommend the Coffee & Talk, personally).
I can't speak to parking, because I walked everywhere or took an Uber. But from a safety perspective, I walked through the area from 8 am-1:30 am and did not feel threatened (at 1:30, I didn't feel smart, but I also didn't feel endangered).
So, 5 out of 5, would even recommend to friends and family.