We stayed for one week and had a delightful time in San Diego. You have to have a car (this is California after all) but one could walk to several restaurants and a new small Target store for the basic necessities including food. Major tourist destinations were within a few minutes driving distance which for us was great. The interior was very clean, the kitchen cabinets stocked with spices and condiments. It is a small place and I wouldn't want to be there with more than just my wife.
As other reviews have said the place is a converted garage so it is cozy and very close to the owner's home. This proved a disadvantage to us as work was being done on their home and workmen were right outside our bedroom window most mornings. Another house was being built behind us and so there was a lot of noise. If those things weren't happening it was a quiet neighborhood.
We never met the owners but had the sense that if we needed anything they could be contacted and would respond quickly.