Great stay in San Diego! This place worked well as a home base for our first multi-day trip with a young toddler. The hosts were very thoughtful about putting out the highchair and pack'n'play, which meant much less packing for us!
If you are traveling with little ones, you'll need to do a quick sweep of the place to childproof it - move the pretty but breakable glass items, etc. There's also a floor level transition bump between the kitchen and hallway area, which both my wife and toddler slipped on a couple times - be sure to watch your step there.
That said: nice central location. Listing was as advertised, tastefully decorated and with plenty of all amenities both indoors and in the backyard. The upstairs tenant was pretty quiet, did not disturb us or our sleeping child. Street parking was easy, though you do hear quite a bit of the street traffic from inside. Good communication with hosts, and the personalized Scrabble board welcome at the entrance was a memorable touch. We would definitely stay here again.