We stayed 6 nights at Mary’s house and it was a great base for exploring the city. Potrero Hill is a lovely area but very hilly (great views!] - so do factor that into planning. Mary’s house is spacious, nicely furnished, very well equipped - and spotless. Internally and externally there’s plenty of space to relax ( inc. hot tub ) after a long day out and about.
Others have commented on the many instructions and certain ‘rules’ - but to be honest they weren’t unreasonable requests and didn’t worry us, and it was helpful to have comprehensive information about the features of the house. We’d very happily recommend booking for a San Francisco stay.