We couldn't have hoped for a more ideal stay. Cindy is a wonderfully warm and welcoming woman, who happens to know more about the ins & outs of San Francisco than probably anybody. Her home is a beautiful and unique place, within walking distance of everything you need, while having a private little garden where you can't even hear traffic. The room is like a book-lover's fantasy retreat. If we're ever in San Francisco again, there's no doubt about where we'd stay.
There is a good bike-hire shop across the road (The Bike Connection) that is cheaper than most, a couple of decent cafes & restaurants on the block (Brainwash, Rocco's), and an excellent supermarket around the corner (Harvest Urban Market). Folsom Street is probably the most cycle-friendly route straight to the Ferry Building - no more than 10m, or 30m on foot.
As the house is less than 10m walk from the BART stop at Civic Centre, it really couldn't be a better location. If you want to learn about the soul and history of SF, this is the place to come.