You're thinking about it. Just do it! pHIll is an amazing location! Grab a Lime and zip to SoMa for work, or ramble the 10 minute walk to the Dog Patch and all the hipster nightlife has to offer, or a quick 5 minute walk to 18th for an array of gastronomy and the local pub. Regardless, you will find yourself back at 455 Pennsylvania, snuggled in a comfy bed in the safety and quietude of potrero hill. It doesn't get much better.
Note, you're in a private flat, but there is a tenant above, so if you are super sensitive to the idea of sharing floor/ceiling space...