We really had a great time in SF, enjoying both the city and the flat : great location, really clean, veeeeeeery confortable (you really have to want to visit the city to get out the sofa), the person at the desk was very helpful, and there is an extraordinary view from the roof of the building.
There's a cable car stop right outside the building, and several bus stops a few meters further, so it's really easy to move in SF from there.
Only one drawback : having a cable car stop just below the window is cool, but also very noisy, so you may near some earplugs (hope I'm using the right word) if you sleep in the bedroom by the street.
I'll certainly try to go back there if I come back in SF.