We just finished our week long stay at Hotel Bianca and found it to be an awesome experience.
It is not the most central apartment in San Francisco, however the Public Transport access is very close and easy to use, and the neighbourhood is lovely and quiet with interesting shops close by. Also the Stonestown Galleria is a short bus ride away if you fancy some local shopping.
The apartment itself is perfect for a couple. It is clean and bright with an ocean view and an amazingly comfortable bed.
We will definitely be revisiting this "hotel" next time we are in SF.