What an awesome stay!
Michael and Nicole's place is situated in a really calm and lovely area of San Francisco. It was super close to the main city (using the buses which stop about a minute or two's walk from the home) and thus provides really easy access to the city centre (Union Square, Chinatown) as well as the more hip areas (like the Mission!)
San Francisco itself is a great place to explore but be prepared for a lot of walking once your there but one thing is for sure - Michael and Nicole's place is a gem for exploring as well as returning too after a long day!
The area itself felt really safe compared to other areas in SF and has some great breakfast places (Moonlight cafe healthy breakfast was yummmmm) as well as plenty of restaurants and a brewery (Barebottle) which usually has a good food truck too.
Don't hesitate - book!