We came to SF for a specific event but I wished we'd booked the space for more days and stayed to visit SF longer. The host is wonderful, very easy to communicate with and helpful. The place is really nice, at night it's very quiet specially for me living in Atlanta I noticed the lack of traffic noise, sirens, bar & nightclub noise, etc. Even though, there's all kinds of activity and night life less than half a block away on 16th street.
The bedrooms are at opposite ends of the apartment, the kitchen is nice and the hosts provide you coffee, snacks and even food!
The only caveat I'd offer is to avoid renting a car unless you must have it. Parking around the neighborhood and much of SF is not easy to find. Walking, public transport and Uber/Lift will serve you better.
All said and done, I'd come back to Doris' AirBnB in a heart beat if possible. Great place to stay in the Mission District.