Fantastic location in Potrero Hill, right near the 22nd st Caltrain and a very short walk from a bunch of great restaurants. The atmosphere is really typical San Francisco.
The hosts Ed and Chris are awesome. I've stayed with them before, and I'll absolutely stay with them again - they're warm, generous, friendly and attentive. The fridge is stocked with various drinks, there are plenty of coupons for local restaurants and I always felt like either Ed or Chris was available to help me if anything came up. I cannot recommend this place highly enough!