We had a great stay for 8 nights - apartment is very clean and airy - it is only 5 min walk from the MUNI "Castro" stop which gets you down to the Embarcadero in 10 mins, off peak.
The F streetcar stops 5 mins away too but that take a good bit longer, though it is above ground so you can see more of how the city looks - it takes about 45 mins to get to Fisherman's Wharf at the end of the line.
The 16th and Mission BART stop is a 10-15 min walk from the house.
There is a wonderful array of food nearby - we ate mainly on Valencia St, about 10 min walk away - that had big crowds filling up the many spots - Beretta and West of Pecos were two we liked especially.
Todd and Amy were very friendly and welcoming and were available if we had any questions.
SF is a great city and is changing a lot - Market St is being overhauled big time so there are (slightly) fewer homeless crazies wandering about in its mid section.
And weather was superb - it beats the Jan snow in NYC.
Recommend it highly!