First of all, Chan is a very welcoming and communicative host. Checking in and out was easy with a little arrangement beforehand, even at odd hours. He even graciously helped me recover an important item that I stupidly left behind at the end of my trip, for which I am eternally grateful.
If you don't mind some neighborhood noise at night and sharing bathrooms (I'm used to both of those), then the location is great. Lots of walkable food at almost all hours of the day, groceries with lots of fresh produce and international products, bars and restaurants, laundromats, nearby public transportation, and plenty of people out and about. It's especially a nice area to be in if you speak Spanish, since Spanish is ubiquitous in the neighborhood, but of course businesses welcome people who don't speak Spanish, too. It was not usually chilly and never foggy. There are fans in the rooms because it gets warm, so don't pack for just cool weather or you'll probably be hot in the middle of the day and at the start of the night. The kitchen and living area are a good size. I was out most of the time but never felt like the other guests and I were living right on top of each other when I was there. If you're a woman travelling solo, you can confidently stay here. I and two other guests there at overlapping times were young women travelling alone. I had no trouble while riding public transportation and walking the streets alone at night, either.
It's not so close to a lot of the touristy stuff, but I had little trouble getting wherever I wanted in SF, over to Oakland and down to San Jose via public transportation and ridesharing apps. The Mission District always seems to have Uber and Lyft drivers milling around. I scheduled a 4:00 AM Uber ride request to the Oakland airport in advance and had a driver show up promptly.