We could not have asked for a better airbnb from which to explore San Francisco and the Bay Area beyond. The location is on a quiet side street across from a park and playground, but only a couple of blocks from all the Mission has to offer: Tartine, Dolores Park, Bi-Rite, taquerias, murals, coffee shops, designers, and on and on. The unit itself is clean and newly remodeled if somewhat no-frills -- nicer than most in the city. As hosts, Daniel and Shanshan were helpful but mostly gave us our space to enjoy their apartment.
My only caveat is that the Mission is currently the epicenter of a heated debate over gentrification and rising rents in San Francisco, and many neighborhood residents (though none we encountered in this building) view airbnb (rightly or wrongly) as a major culprit. Of course no single owner is to blame, and we had a very enjoyable stay -- but had we been aware of the controversy we might have chosen to stay in a different neighborhood.