I stayed with Michelle for a conference in downtown San Francisco and had a rental car. I parked directly in front of the house. The location of the appartment is such that it takes 15min by car or taxi into town. Public transport is also close by. The location is also great for getting around in the Bay Area and visit places further south or accross the bay.
The appartment was easy to access at any time. There was water and snacks, coffee and tea, shampoo and towels. Basically, it felt like a hotel but improved. I was alone, but 4 people have comfortable space with 2 bed / 2 bath, living room and kitchen.
Totally recommended, specifically for those who prefer to not stay directly in downtown San Francisco. The area is safe, clean and calm and ideal start for exploring San Francisco and its surroundings for families and groups of people.