We stayed with Melissa 4 days and loved her house the moment we entered it; room was big & clean and sleeping was good and no noise from street. Our daughter even got a room of herself, which we liked so much!
Melissa & her family & Pete were very nice hosts and let us have all the room we wanted.
Parking in street was no problem (although Mill Street is a steep hill).

For visiting San Francisco by public transport, as we did most the time, you must allow at least 45-60 min (depends on rush hours also) from Melissa to Market Street/ Donwtown (we often used Xpress bus 8X, which is popular with the locals). The neighbourhood Visitacion Valley has no infrastructure but is a quiet suburb. Next street for shopping & restaurants is Mission Street.

We can recommend Melissa as a perfect stay especially for families as long as you do not care a longer approach into town.