This place offers great value for the money. I stayed here while at the conference at the near-by (and very expensive) Hilton at Union Square. The Hilton is only 1.5 blocks away, close enough to go with ease back and forth from The Bartlett with ease as needed. Also on the bright side, the The Bartlett is just 2 short blocks away from Powell St. Station; it was easy for me to walk that with two full pieces of luggage to get on the BART or historic cable cars. As you'll find in other reviews, the area has homeless around the clock and hookers at night offering their services, yet I had no issue walking past them at any time.
If your room is on the street side, you will get the expected noise, which may be an issue for you if you don't have a deep enough sleep. I was on the 5th floor and slept well.
Keep in mind that the elevator is going out of service in February 2020 (so I was told), and the stairs are pretty steep. Thus, if you are coming in with heavy of big luggage, make sure you are on the lower floors. Granted the elevator comes back to service in the future, I'd be glad to stay here again.