Serena's place is very comfortable. Plenty of local cafés, shops, main bus routes within a 15 minute walk. St Francis Fountain diner was great for breakfast. We mainly used Uber/Lyft to the city approx 15 to 20 dollars a ride. Local Walgreens sell you clipper cards with a one day visitor transport pass for 12 dollars includes unlimited cable car rides. The clipper card also gets you Sausalito ferry for 7 dollars each way. Tommy's Joynt diner on Van Ness/Geary is fantastic. Also liked the Wipeout diner on Pier 39. Best tour was San Francisco love bus with Doug, 2 hours and goes down all the streets the big tour buses can't - hilarious trip.