Jake and Charlotte's place is absolutely lovely, especially if you're bringing a dog with you! It is in a quiet neighborhood that gives you easy access to Santa Monica, Venice, Culver City, and so on, includes a parking spot, and has a wonderfully decorated back garden you can relax in and let your dog roam around (hence the previous comment around bringing a dog). It has all the amenities you'd need, and I was especially glad to have AC since it can get quite hot – the guesthouse seems to have previously been a detached garage, so you're right under the roof.
The check-in process was smooth with clear descriptions, which was useful due to arriving after midnight, and Jake and Charlotte were overall very accommodating. They made it possible to have slightly later check-out, and even offered to refund us one night after there was a power and internet outage (which was obviously out of their control, but came back quickly enough).
The only con that'd I'd call out – although it didn't particularly affect my experience – is that the listing is slightly misleading. The guesthouse is listed as having 1 bedroom, but it's actually a studio (which isn't apparent from the photos), and the dedicated workspace with wi-fi well-suited for working was a small dining table with internet on the slower side.
So, would I recommend the place? Absolutely, it was extremely pleasant to be there. Is it good for a business trip? Depends on the type of the trip and the kind of work you do, but it was fine for me.