If location is your top concern, this location is next to everything. The same goes if you value a responsive host.
However, we do not recommend here as 1) the dishwasher contained dirty dishes; 2) the windows do not provide much protection from the elements and noise; and 3) mice.

We discovered dirty dishes in the dishwasher, the host sent over a cleaner the next day.

During rain, water leaked from some windows. The cracks were not surprising, as the windows provided almost no sound absorption.
Those in the alley sounded practically next to you; which makes for an unideal place to work remotely.

The biggest detractor was waking up to a mouse and then having to catch and exterminate the critter is unacceptable. We had purchased our own traps to expedite things (wisely, as it took 3 days for the host's shipment). The handyman confirmed there was a hole behind the stove and insinuated mice lived in the garage below too.

The host never apologized and denied any refund.