If you want to be in DTLA - with everything that comes with DTLA - this is a great location. It felt safe to me as the really dodgy areas of DTLA are far enough away. There are supermarkets, restaurants and bars all walkable and the loft was one of the cleanest I have ever stayed in!
You hear your neighbors from above you if you are sensitive to that... but that is the only little downside to this listing.