We enjoyed our stay at this house in New Islington, it's in a good location and gave our family (1 grandparent/2 parents/1child) the space we needed. We found the location excellent, with easy access from the airport and on to the ring road when we were driving, with offstreet parking in the paved backyard.
But most of the time we walked into the city as it's comfortable walking distance (<20min) to the Northern Quarter, either by main road or via the nicer canals/mills walking routes. We also walked from near the house via the Ashton Canal towpath all the way to Deansgate, or took the quick route to the city centre via Ancoats & Northern Quarter on the Rochford Canal. An Uber was just 3-4 pounds into town.
The house is compact but had enough seating (lounge and dining), to comfortably seat 4 of us. It does have internal stairs that my elderly mother struggled with a bit at times (bathroom is upstairs) but was fine for the rest of the family. The decor is modern with floorboards and the kitchen and bathroom were good. In fact it had the best shower I've had in the UK, and continuous hot water. There was a nice large tv and good WIFI too plus some good tech for the heating system. There was also a washing machine, iron and hair dryer which were handy. The only thing it didn't have that we missed was a dishwasher.
This house is in an up and coming neighbourhood, while it looks a bit average (not unsafe, just not very beautiful) on this part of the street, nearby are a number of redevelopments of mill buildings and canal which are close to being finished. There should be more food/shop options even closer then, although there is an Aldi about 10min walk away on the main road into town.
Leo was a communicative host and his info and responsiveness were good. Overall would definitely stay here again on a return visit to Manchester.